CIOIN|Ensembl=ENSCING00000004717.3|UniProtKB=F6QN05 F6QN05 LOC100184826 PTHR23149:SF9 G PATCH DOMAIN CONTAINING PROTEIN G PATCH DOMAIN-CONTAINING PROTEIN 4 intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000018059.1|UniProtKB=Q2PEE2 Q2PEE2 Ci-LC3 PTHR21255:SF4 T-COMPLEX-ASSOCIATED-TESTIS-EXPRESSED 1/ DYNEIN LIGHT CHAIN DYNEIN LIGHT CHAIN TCTEX-TYPE protein binding#GO:0005515;binding#GO:0005488 microtubule-based movement#GO:0007018;cellular process#GO:0009987;microtubule-based process#GO:0007017 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;microtubule cytoskeleton#GO:0015630;dynein complex#GO:0030286;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic dynein complex#GO:0005868;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;microtubule or microtubule-binding cytoskeletal protein#PC00157 CIOIN|Ensembl=ENSCING00000006648.3|UniProtKB=F6U088 F6U088 PTHR24212:SF8 ZYXIN/TRIP6 LIM ZINC FINGER DOMAIN CONTAINING PROTEIN cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 CIOIN|Ensembl=ENSCING00000024579.1|UniProtKB=H2Y3H7 H2Y3H7 PTHR14647:SF87 GALACTOSE-3-O-SULFOTRANSFERASE PUTATIVE-RELATED transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000004871.3|UniProtKB=F6SPL0 F6SPL0 PTHR11474:SF126 TYROSINASE FAMILY MEMBER TYROSINASE-LIKE PROTEIN TYR-1-RELATED oxygenase#PC00177;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000005025.3|UniProtKB=F6TXH2 F6TXH2 PTHR10699:SF27 NEUROMODULIN RIIA DOMAIN-CONTAINING PROTEIN protein binding#GO:0005515;calmodulin binding#GO:0005516;binding#GO:0005488 CIOIN|Ensembl=ENSCING00000004588.3|UniProtKB=F6WPZ9 F6WPZ9 PTHR23302:SF24 TRANSMEMBRANE CHANNEL-RELATED TMC DOMAIN-CONTAINING PROTEIN ion channel#PC00133;transporter#PC00227 CIOIN|Ensembl=ENSCING00000012246.2|UniProtKB=H2XY38 H2XY38 LOC100181653 PTHR12143:SF19 PEPTIDE N-GLYCANASE PNGASE -RELATED PEPTIDE-N(4)-(N-ACETYL-BETA-GLUCOSAMINYL)ASPARAGINE AMIDASE hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824 carbohydrate derivative metabolic process#GO:1901135;macromolecule catabolic process#GO:0009057;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;carbohydrate derivative catabolic process#GO:1901136;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycoprotein metabolic process#GO:0009100 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 hydrolase#PC00121 Oxidative stress response#P00046>TRX#P01122;Hypoxia response via HIF activation#P00030>Thioredoxin#P00825 CIOIN|Ensembl=ENSCING00000006948.3|UniProtKB=F6UZU2 F6UZU2 LOC100180904 PTHR10253:SF5 POLYCOMB PROTEIN POLYCOMB PROTEIN EED nucleosome binding#GO:0031491;protein-containing complex binding#GO:0044877;chromatin binding#GO:0003682;binding#GO:0005488 negative regulation of gene expression#GO:0010629;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;protein-DNA complex organization#GO:0071824;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;regulation of transcription by RNA polymerase II#GO:0006357;heterochromatin formation#GO:0031507;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;negative regulation of biosynthetic process#GO:0009890;regulation of DNA-templated transcription#GO:0006355;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;negative regulation of gene expression, epigenetic#GO:0045814;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;epigenetic regulation of gene expression#GO:0040029;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;negative regulation of macromolecule biosynthetic process#GO:0010558;heterochromatin organization#GO:0070828;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;protein-containing complex organization#GO:0043933;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;chromatin organization#GO:0006325;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;chromatin remodeling#GO:0006338;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;histone methyltransferase complex#GO:0035097;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nucleoplasm#GO:0005654;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;methyltransferase complex#GO:0034708;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;PcG protein complex#GO:0031519;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 chromatin/chromatin-binding, or -regulatory protein#PC00077 CIOIN|Ensembl=ENSCING00000006636.3|UniProtKB=F6U189 F6U189 PTHR46437:SF1 MORN REPEAT-CONTAINING PROTEIN 5 MORN REPEAT-CONTAINING PROTEIN 5 CIOIN|Ensembl=ENSCING00000018641.1|UniProtKB=H2XQN0 H2XQN0 PTHR11480:SF93 SAPOSIN-RELATED SAPOSIN B-TYPE DOMAIN-CONTAINING PROTEIN scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000012913.2|UniProtKB=F6Q0V4 F6Q0V4 LOC100180880 PTHR31220:SF1 HYCCIN RELATED GH21176P lipid metabolic process#GO:0006629;cellular localization#GO:0051641;phospholipid biosynthetic process#GO:0008654;macromolecule localization#GO:0033036;organophosphate biosynthetic process#GO:0090407;phosphatidylinositol biosynthetic process#GO:0006661;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;lipid biosynthetic process#GO:0008610;phosphatidylinositol phosphate biosynthetic process#GO:0046854;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;protein localization to plasma membrane#GO:0072659;localization within membrane#GO:0051668;protein localization to membrane#GO:0072657;glycerolipid biosynthetic process#GO:0045017;cellular metabolic process#GO:0044237;glycerophospholipid metabolic process#GO:0006650;phosphatidylinositol metabolic process#GO:0046488;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;protein localization#GO:0008104;primary metabolic process#GO:0044238;localization#GO:0051179;protein localization to cell periphery#GO:1990778;cellular macromolecule localization#GO:0070727;glycerophospholipid biosynthetic process#GO:0046474;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 CIOIN|Ensembl=ENSCING00000012408.2|UniProtKB=F6YPW9 F6YPW9 PTHR43539:SF23 FLAVIN-BINDING MONOOXYGENASE-LIKE PROTEIN (AFU_ORTHOLOGUE AFUA_4G09220) FAD-DEPENDENT OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN 2 nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;flavin adenine dinucleotide binding#GO:0050660;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;anion binding#GO:0043168;oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497 response to organic substance#GO:0010033;macromolecule catabolic process#GO:0009057;cellular response to stimulus#GO:0051716;response to endoplasmic reticulum stress#GO:0034976;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;response to organonitrogen compound#GO:0010243;ERAD pathway#GO:0036503;cellular process#GO:0009987;primary metabolic process#GO:0044238;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;cellular response to stress#GO:0033554;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;endoplasmic reticulum lumen#GO:0005788;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 oxygenase#PC00177;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000014429.1|UniProtKB=F6YUW7 F6YUW7 PTHR15467:SF9 ZINC-FINGERS AND HOMEOBOXES RELATED HOMEOBOX DOMAIN-CONTAINING PROTEIN transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 CIOIN|Ensembl=ENSCING00000020383.1|UniProtKB=H2XVK4 H2XVK4 PTHR46680:SF3 NF-KAPPA-B INHIBITOR ALPHA NF-KAPPA-B INHIBITOR CACTUS Toll pathway-drosophila#P06217>CACT#P06342 CIOIN|Ensembl=ENSCING00000014907.2|UniProtKB=F6Y813 F6Y813 PTHR31102:SF1 FAMILY NOT NAMED CATION_H+ EXCHANGER DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000023255.1|UniProtKB=H2XY48 H2XY48 LOC100177421 PTHR10426:SF88 STRICTOSIDINE SYNTHASE-RELATED ADIPOCYTE PLASMA MEMBRANE-ASSOCIATED PROTEIN HEMOMUCIN-RELATED hydrolase activity#GO:0016787;catalytic activity#GO:0003824 CIOIN|Ensembl=ENSCING00000024193.1|UniProtKB=H2XSN9 H2XSN9 PTHR20889:SF12 PHOSPHATASE, ORPHAN 1, 2 LP01149P hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 hydrolase#PC00121;phosphatase#PC00181 CIOIN|Ensembl=ENSCING00000003208.3|UniProtKB=F6S3H3 F6S3H3 PTHR16138:SF7 MYCOPHENOLIC ACID ACYL-GLUCURONIDE ESTERASE, MITOCHONDRIAL PALMITOYL-PROTEIN THIOESTERASE ABHD10, MITOCHONDRIAL esterase#PC00097 CIOIN|Ensembl=ENSCING00000003346.3|UniProtKB=F6TE43 F6TE43 PTHR46830:SF1 TRANSFERASE, PUTATIVE-RELATED ALPHA-1,4-N-ACETYLGLUCOSAMINYLTRANSFERASE transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000014458.2|UniProtKB=F6YAS9 F6YAS9 PTHR45617:SF173 LEUCINE RICH REPEAT FAMILY PROTEIN RE54577P scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000007024.3|UniProtKB=F7AE51 F7AE51 LOC100186818 PTHR12949:SF0 RNA POLYMERASE III DNA DIRECTED -RELATED DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC3 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;DNA-directed RNA polymerase complex#GO:0000428;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695;RNA polymerase complex#GO:0030880;protein-containing complex#GO:0032991;nuclear DNA-directed RNA polymerase complex#GO:0055029;RNA polymerase III complex#GO:0005666;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 RNA metabolism protein#PC00031;DNA-directed RNA polymerase#PC00019 CIOIN|Ensembl=ENSCING00000009048.3|UniProtKB=F6R6C4 F6R6C4 PTHR14152:SF5 SQUAMOUS CELL CARCINOMA ANTIGEN RECOGNISED BY CYTOTOXIC T LYMPHOCYTES U4_U6.U5 TRI-SNRNP-ASSOCIATED PROTEIN 1 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;RNA processing#GO:0006396;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;mRNA cis splicing, via spliceosome#GO:0045292;ncRNA metabolic process#GO:0034660;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;ribosome biogenesis#GO:0042254;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;rRNA metabolic process#GO:0016072;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;ribonucleoprotein complex biogenesis#GO:0022613;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375 ribonucleoprotein complex#GO:1990904;spliceosomal snRNP complex#GO:0097525;small nuclear ribonucleoprotein complex#GO:0030532;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;spliceosomal tri-snRNP complex#GO:0097526;U4/U6 x U5 tri-snRNP complex#GO:0046540;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 extracellular matrix protein#PC00102 CIOIN|Ensembl=ENSCING00000024304.1|UniProtKB=H2XTF1 H2XTF1 PTHR43290:SF2 MEVALONATE KINASE MEVALONATE KINASE carbohydrate kinase#PC00065 Cholesterol biosynthesis#P00014>Mevalonate kinase#P00492 CIOIN|Ensembl=ENSCING00000020305.1|UniProtKB=F6TE65 F6TE65 PTHR31102:SF1 FAMILY NOT NAMED CATION_H+ EXCHANGER DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000005060.3|UniProtKB=F7A4V3 F7A4V3 PTHR15140:SF31 TUBULIN-SPECIFIC CHAPERONE E TUBULIN-SPECIFIC CHAPERONE E chaperone#PC00072 CIOIN|Ensembl=ENSCING00000020123.1|UniProtKB=H2XZQ0 H2XZQ0 PTHR45973:SF23 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT SDS22-RELATED PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 7 phosphatase modulator#PC00184 CIOIN|Ensembl=ENSCING00000005140.3|UniProtKB=F6VAX6 F6VAX6 PTHR12294:SF1 EF HAND DOMAIN FAMILY A1,A2-RELATED CALCIUM UPTAKE PROTEIN 1, MITOCHONDRIAL cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488 inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;calcium ion transmembrane transport#GO:0070588;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;homeostatic process#GO:0042592;monoatomic cation homeostasis#GO:0055080;inorganic ion transmembrane transport#GO:0098660;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;cellular process#GO:0009987;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;calcium ion transport#GO:0006816;monoatomic ion homeostasis#GO:0050801;localization#GO:0051179;mitochondrial transport#GO:0006839;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation transport#GO:0006812;mitochondrial calcium ion homeostasis#GO:0051560;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion transport#GO:0006811;mitochondrial transmembrane transport#GO:1990542;monoatomic cation transmembrane transport#GO:0098655 envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;transporter complex#GO:1990351;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;calcium channel complex#GO:0034704;membrane#GO:0016020;organelle envelope#GO:0031967;cation channel complex#GO:0034703;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;mitochondrial envelope#GO:0005740;transmembrane transporter complex#GO:1902495;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227;mitochondrial protein-containing complex#GO:0098798 calmodulin-related#PC00061 CIOIN|Ensembl=ENSCING00000001428.3|UniProtKB=F6YRG2 F6YRG2 PTHR10844:SF32 CAVEOLIN CAVEOLIN-3-LIKE cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;membrane assembly#GO:0071709;membrane organization#GO:0061024;plasma membrane organization#GO:0007009;endomembrane system organization#GO:0010256;cellular component organization#GO:0016043;cellular process#GO:0009987 plasma membrane raft#GO:0044853;caveola#GO:0005901;plasma membrane region#GO:0098590;membrane raft#GO:0045121;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;membrane microdomain#GO:0098857;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000022315.1|UniProtKB=H2XKQ2 H2XKQ2 LOC100182309 PTHR24024:SF18 PULMONARY SURFACTANT-ASSOCIATED PROTEIN A SHORT-CHAIN COLLAGEN C4-LIKE extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 surfactant#PC00212;structural protein#PC00211 CIOIN|Ensembl=ENSCING00000003107.3|UniProtKB=F6RD78 F6RD78 rcc1 PTHR45982:SF1 REGULATOR OF CHROMOSOME CONDENSATION REGULATOR OF CHROMOSOME CONDENSATION CIOIN|Ensembl=ENSCING00000002598.3|UniProtKB=F6TR45 F6TR45 LOC100178727 PTHR46228:SF2 KELCH DOMAIN-CONTAINING PROTEIN KELCH REPEAT PROTEIN (AFU_ORTHOLOGUE AFUA_4G14350) CIOIN|Ensembl=ENSCING00000013797.1|UniProtKB=F6R9Z3 F6R9Z3 PTHR24253:SF178 TRANSMEMBRANE PROTEASE SERINE TRANSMEMBRANE PROTEASE SERINE 12 serine protease#PC00203;protease#PC00190 CIOIN|Ensembl=ENSCING00000002713.3|UniProtKB=F6UDV5 F6UDV5 LOC100177262 PTHR24240:SF223 OPSIN MELATONIN RECEPTOR 1B signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 signal transduction#GO:0007165;response to light stimulus#GO:0009416;cellular response to stimulus#GO:0051716;detection of stimulus#GO:0051606;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;regulation of cellular process#GO:0050794;response to radiation#GO:0009314;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;response to abiotic stimulus#GO:0009628;signaling#GO:0023052;cellular response to light stimulus#GO:0071482 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 CIOIN|Ensembl=ENSCING00000005222.3|UniProtKB=F6YI64 F6YI64 LOC100183036 PTHR11599:SF12 PROTEASOME SUBUNIT ALPHA/BETA PROTEASOME SUBUNIT ALPHA TYPE-1 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 peptidase complex#GO:1905368;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;proteasome complex#GO:0000502;endopeptidase complex#GO:1905369;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 protease#PC00190;protein modifying enzyme#PC00260 Parkinson disease#P00049>20S proteasome#P01227 CIOIN|Ensembl=ENSCING00000004809.3|UniProtKB=F6RDT5 F6RDT5 PTHR28583:SF4 ACID AMIDASE N-ACYLETHANOLAMINE-HYDROLYZING ACID AMIDASE hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;catalytic activity#GO:0003824 cysteine protease#PC00081;protease#PC00190 CIOIN|Ensembl=ENSCING00000020013.1|UniProtKB=H2XLC8 H2XLC8 PTHR31186:SF1 MODULATOR OF SMOOTHENED PROTEIN MODULATOR OF SMOOTHENED PROTEIN regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;negative regulation of response to stimulus#GO:0048585;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648 bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;ciliary membrane#GO:0060170;Golgi apparatus#GO:0005794;organelle membrane#GO:0031090;cell projection membrane#GO:0031253;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;plasma membrane region#GO:0098590;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cilium#GO:0005929;plasma membrane#GO:0005886 CIOIN|Ensembl=ENSCING00000014465.2|UniProtKB=F6YAH3 F6YAH3 PTHR12913:SF1 UNR PROTEIN N-RAS UPSTREAM GENE PROTEIN COLD SHOCK DOMAIN-CONTAINING PROTEIN E1 CIOIN|Ensembl=ENSCING00000009307.3|UniProtKB=F7A5V7 F7A5V7 PTHR19923:SF0 WD40 REPEAT PROTEINPRL1/PRL2-RELATED PLEIOTROPIC REGULATOR 1 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704 ribonucleoprotein complex#GO:1990904;catalytic step 2 spliceosome#GO:0071013;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;precatalytic spliceosome#GO:0071011;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;Prp19 complex#GO:0000974;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000001982.3|UniProtKB=F6X3P0 F6X3P0 LOC100175666 PTHR22599:SF11 MPS ONE BINDER KINASE ACTIVATOR-LIKE MOB MOB KINASE ACTIVATOR-LIKE 3 protein kinase activator activity#GO:0030295;protein kinase regulator activity#GO:0019887;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047;kinase regulator activity#GO:0019207;enzyme regulator activity#GO:0030234;kinase activator activity#GO:0019209 positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of protein modification process#GO:0031401;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;positive regulation of metabolic process#GO:0009893;positive regulation of biological process#GO:0048518;signaling#GO:0023052;positive regulation of protein phosphorylation#GO:0001934;positive regulation of phosphorylation#GO:0042327;cellular response to stimulus#GO:0051716;positive regulation of phosphorus metabolic process#GO:0010562;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;positive regulation of phosphate metabolic process#GO:0045937;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of protein phosphorylation#GO:0001932;biological regulation#GO:0065007;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 kinase modulator#PC00140;kinase activator#PC00138 CIOIN|Ensembl=ENSCING00000014134.1|UniProtKB=F7ASL8 F7ASL8 LOC100183109 PTHR23055:SF198 CALCIUM BINDING PROTEINS NEURONAL CALCIUM SENSOR 1 cation binding#GO:0043169;molecular function activator activity#GO:0140677;small molecule binding#GO:0036094;molecular function regulator activity#GO:0098772;binding#GO:0005488;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;enzyme activator activity#GO:0008047;ion binding#GO:0043167;enzyme regulator activity#GO:0030234 calmodulin-related#PC00061 CIOIN|Ensembl=ENSCING00000012012.2|UniProtKB=F7B757 F7B757 PTHR44942:SF4 METHYLTRANSF_11 DOMAIN-CONTAINING PROTEIN METHYLTRANSFERASE TYPE 11 DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000022660.1|UniProtKB=H2XPZ2 H2XPZ2 PTHR10811:SF5 FRINGE-RELATED FRINGE GLYCOSYLTRANSFERASE acetylglucosaminyltransferase activity#GO:0008375;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194;hexosyltransferase activity#GO:0016758 glycosyltransferase#PC00111;metabolite interconversion enzyme#PC00262 Notch signaling pathway#P00045>Fringe#P01107 CIOIN|Ensembl=ENSCING00000002546.3|UniProtKB=I6L212 I6L212 PTHR42679:SF2 S-METHYL-5'-THIOADENOSINE PHOSPHORYLASE S-METHYL-5'-THIOADENOSINE PHOSPHORYLASE transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;pentosyltransferase activity#GO:0016763;catalytic activity#GO:0003824 organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;proteinogenic amino acid metabolic process#GO:0170039;sulfur compound metabolic process#GO:0006790;proteinogenic amino acid biosynthetic process#GO:0170038;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;aspartate family amino acid biosynthetic process#GO:0009067;alpha-amino acid biosynthetic process#GO:1901607;nitrogen compound metabolic process#GO:0006807;amino acid biosynthetic process#GO:0008652;alpha-amino acid metabolic process#GO:1901605;aspartate family amino acid metabolic process#GO:0009066;small molecule biosynthetic process#GO:0044283;L-amino acid biosynthetic process#GO:0170034;carboxylic acid metabolic process#GO:0019752;L-amino acid metabolic process#GO:0170033;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 nucleotide kinase#PC00172 Purine metabolism#P02769>Nucleoside Phosphorylase#P03115 CIOIN|Ensembl=ENSCING00000020969.1|UniProtKB=H2Y1Y9 H2Y1Y9 LOC100175056 PTHR15691:SF6 WASH COMPLEX SUBUNIT 5 WASH COMPLEX SUBUNIT 5 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;regulation of organelle organization#GO:0033043;protein-containing complex assembly#GO:0065003;endomembrane system organization#GO:0010256;actin polymerization or depolymerization#GO:0008154;regulation of actin filament organization#GO:0110053;actin filament polymerization#GO:0030041;regulation of cellular component organization#GO:0051128;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of supramolecular fiber organization#GO:1902903;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;endosome organization#GO:0007032;regulation of cytoskeleton organization#GO:0051493;actin filament-based process#GO:0030029;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;regulation of cellular process#GO:0050794;supramolecular fiber organization#GO:0097435;biological regulation#GO:0065007;protein polymerization#GO:0051258;actin filament organization#GO:0007015;regulation of actin cytoskeleton organization#GO:0032956;vesicle organization#GO:0016050;organelle fission#GO:0048285;cytoskeleton organization#GO:0007010;regulation of actin filament-based process#GO:0032970;actin cytoskeleton organization#GO:0030036 cytoplasm#GO:0005737;endosome#GO:0005768;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular vesicle#GO:0097708;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150 CIOIN|Ensembl=ENSCING00000007581.3|UniProtKB=F7A429 F7A429 PTHR43195:SF1 TRANSKETOLASE FI06132P-RELATED cation binding#GO:0043169;transferase activity#GO:0016740;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;anion binding#GO:0043168 metabolite interconversion enzyme#PC00262;transketolase#PC00221 CIOIN|Ensembl=ENSCING00000006411.3|UniProtKB=F6QWQ4 F6QWQ4 PTHR42884:SF28 PROPROTEIN CONVERTASE SUBTILISIN/KEXIN-RELATED PROPROTEIN CONVERTASE SUBTILISIN_KEXIN TYPE 7 hydrolase activity#GO:0016787;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;protein processing#GO:0016485;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 bounding membrane of organelle#GO:0098588;trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791;Golgi membrane#GO:0000139 serine protease#PC00203;protein modifying enzyme#PC00260 Alzheimer disease-presenilin pathway#P00004>Furin#P00157;Alzheimer disease-amyloid secretase pathway#P00003>Furin#P00105 CIOIN|Ensembl=ENSCING00000012649.2|UniProtKB=F6URY8 F6URY8 PTHR10472:SF1 D-TYROSYL-TRNA TYR DEACYLASE D-AMINOACYL-TRNA DEACYLASE 2 catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity#GO:0016787;catalytic activity, acting on RNA#GO:0140098;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;tRNA metabolic process#GO:0006399;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 esterase#PC00097;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000020918.1|UniProtKB=F8WQ81 F8WQ81 LOC100185684 PTHR10334:SF591 CYSTEINE-RICH SECRETORY PROTEIN-RELATED GLIOMA PATHOGENESIS-RELATED PROTEIN 1-LIKE extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 defense/immunity protein#PC00090 CIOIN|Ensembl=ENSCING00000001257.3|UniProtKB=F7AEF1 F7AEF1 LOC100184763 PTHR44176:SF1 DNAJ HOMOLOG SUBFAMILY C MEMBER 25 DNAJ HOMOLOG SUBFAMILY C MEMBER 25 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein folding#GO:0006457;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 chaperone#PC00072 CIOIN|Ensembl=ENSCING00000009375.3|UniProtKB=F6WXG6 F6WXG6 PTHR12411:SF642 CYSTEINE PROTEASE FAMILY C1-RELATED PRO-CATHEPSIN H cysteine-type peptidase activity#GO:0008234;peptidase activator activity#GO:0016504;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197;hydrolase activity#GO:0016787;enzyme activator activity#GO:0008047;peptidase regulator activity#GO:0061134;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175;enzyme regulator activity#GO:0030234 positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;protein catabolic process#GO:0030163;positive regulation of molecular function#GO:0044093;organonitrogen compound catabolic process#GO:1901565;regulation of catalytic activity#GO:0050790;regulation of apoptotic signaling pathway#GO:2001233;positive regulation of proteolysis#GO:0045862;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of programmed cell death#GO:0043068;positive regulation of metabolic process#GO:0009893;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;proteolysis#GO:0006508;catabolic process#GO:0009056;regulation of hydrolase activity#GO:0051336;positive regulation of apoptotic signaling pathway#GO:2001235;organic substance catabolic process#GO:1901575;positive regulation of signaling#GO:0023056;protein metabolic process#GO:0019538;positive regulation of biological process#GO:0048518;proteolysis involved in protein catabolic process#GO:0051603;positive regulation of peptidase activity#GO:0010952;organic substance metabolic process#GO:0071704;regulation of programmed cell death#GO:0043067;metabolic process#GO:0008152;positive regulation of apoptotic process#GO:0043065;regulation of proteolysis#GO:0030162;regulation of cell communication#GO:0010646;macromolecule catabolic process#GO:0009057;regulation of apoptotic process#GO:0042981;immune response#GO:0006955;positive regulation of catalytic activity#GO:0043085;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of hydrolase activity#GO:0051345;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of response to stimulus#GO:0048583;immune system process#GO:0002376;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;regulation of peptidase activity#GO:0052547;regulation of metabolic process#GO:0019222 cytoplasm#GO:0005737;lysosome#GO:0005764;intracellular membrane-bounded organelle#GO:0043231;extracellular region#GO:0005576;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;organelle#GO:0043226;lytic vacuole#GO:0000323;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cysteine protease#PC00081;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000000731.3|UniProtKB=F6Q2S6 F6Q2S6 LOC100177538 PTHR21099:SF2 RAD201 SI:CH211-113E8.11 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000024327.1|UniProtKB=H2XSU0 H2XSU0 LOC100181008 PTHR13025:SF6 EF-HAND DOMAIN-CONTAINING PROTEIN D EF-HAND DOMAIN-CONTAINING PROTEIN-RELATED cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488 calmodulin-related#PC00061 CIOIN|Ensembl=ENSCING00000024537.1|UniProtKB=H2XYN5 H2XYN5 PTHR24095:SF14 ACETYL-COENZYME A SYNTHETASE ACETYL-COENZYME A SYNTHETASE 1 ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877 cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;amide metabolic process#GO:0043603;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;acyl-CoA metabolic process#GO:0006637;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 ligase#PC00142;metabolite interconversion enzyme#PC00262 Acetate utilization#P02722>Acetyl-CoA synthetase#P02803 CIOIN|Ensembl=ENSCING00000007437.3|UniProtKB=F7ANR5 F7ANR5 PTHR10644:SF3 DNA REPAIR/RNA PROCESSING CPSF FAMILY DNA DAMAGE-BINDING PROTEIN 1 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA processing factor#PC00147 CIOIN|Ensembl=ENSCING00000001212.3|UniProtKB=F6T8R8 F6T8R8 PTHR12780:SF1 RNA POLYMERASE III DNA DIRECTED , 39KD SUBUNIT-RELATED DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC6 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;DNA-directed RNA polymerase complex#GO:0000428;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695;RNA polymerase complex#GO:0030880;protein-containing complex#GO:0032991;nuclear DNA-directed RNA polymerase complex#GO:0055029;RNA polymerase III complex#GO:0005666;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 DNA metabolism protein#PC00009 CIOIN|Ensembl=ENSCING00000007675.3|UniProtKB=F6T724 F6T724 LOC100187119 PTHR12411:SF586 CYSTEINE PROTEASE FAMILY C1-RELATED CATHEPSIN L-LIKE cysteine-type peptidase activity#GO:0008234;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197 macromolecule catabolic process#GO:0009057;nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;proteolysis#GO:0006508;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;catabolic process#GO:0009056;organonitrogen compound catabolic process#GO:1901565;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;primary metabolic process#GO:0044238 cytoplasm#GO:0005737;lysosome#GO:0005764;intracellular membrane-bounded organelle#GO:0043231;extracellular region#GO:0005576;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;organelle#GO:0043226;lytic vacuole#GO:0000323;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cysteine protease#PC00081;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000000301.3|UniProtKB=F6ZGE9 F6ZGE9 PTHR13303:SF0 PREFOLDIN SUBUNIT 2 PREFOLDIN SUBUNIT 2 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein folding#GO:0006457;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 chaperone#PC00072 CIOIN|Ensembl=ENSCING00000020502.1|UniProtKB=Q1RPY5 Q1RPY5 Ci-ZF(TRAF_RING)-3 PTHR10131:SF152 TNF RECEPTOR ASSOCIATED FACTOR TNF RECEPTOR-ASSOCIATED FACTOR 6 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 response to external biotic stimulus#GO:0043207;signal transduction#GO:0007165;regulation of nitrogen compound metabolic process#GO:0051171;cellular response to lipopolysaccharide#GO:0071222;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;response to lipid#GO:0033993;regulation of RNA biosynthetic process#GO:2001141;regulation of intracellular signal transduction#GO:1902531;cellular response to lipid#GO:0071396;regulation of biological process#GO:0050789;cellular response to oxygen-containing compound#GO:1901701;positive regulation of NF-kappaB transcription factor activity#GO:0051092;response to bacterium#GO:0009617;response to biotic stimulus#GO:0009607;regulation of biosynthetic process#GO:0009889;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;innate immune response#GO:0045087;regulation of macromolecule biosynthetic process#GO:0010556;response to molecule of bacterial origin#GO:0002237;regulation of gene expression#GO:0010468;defense response#GO:0006952;signaling#GO:0023052;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;regulation of DNA-binding transcription factor activity#GO:0051090;immune response#GO:0006955;regulation of DNA-templated transcription#GO:0006355;lipopolysaccharide-mediated signaling pathway#GO:0031663;cellular response to organic substance#GO:0071310;cellular response to biotic stimulus#GO:0071216;cell communication#GO:0007154;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;defense response to symbiont#GO:0140546;response to lipopolysaccharide#GO:0032496;cellular response to molecule of bacterial origin#GO:0071219;positive regulation of DNA-binding transcription factor activity#GO:0051091;regulation of primary metabolic process#GO:0080090;regulation of response to stimulus#GO:0048583;immune system process#GO:0002376;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to stress#GO:0006950;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;defense response to other organism#GO:0098542;response to chemical#GO:0042221;response to other organism#GO:0051707;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of canonical NF-kappaB signal transduction#GO:0043122;cell surface receptor signaling pathway#GO:0007166;biological process involved in interspecies interaction between organisms#GO:0044419;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane protein complex#GO:0098796;receptor complex#GO:0043235;protein-containing complex#GO:0032991;plasma membrane signaling receptor complex#GO:0098802;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 p53 pathway#P00059>TRAF#P04620;p38 MAPK pathway#P05918>TRAF6#P06038;Toll receptor signaling pathway#P00054>TRAF6#P01371;Apoptosis signaling pathway#P00006>TRAF2#P00306 CIOIN|Ensembl=ENSCING00000016910.2|UniProtKB=F6VCE5 F6VCE5 PTHR43050:SF1 SERINE / THREONINE RACEMASE FAMILY MEMBER SERINE RACEMASE carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;magnesium ion binding#GO:0000287;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;metal ion binding#GO:0046872;isomerase activity#GO:0016853;cation binding#GO:0043169;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;lyase activity#GO:0016829;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167;ATP binding#GO:0005524 organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;alpha-amino acid biosynthetic process#GO:1901607;nitrogen compound metabolic process#GO:0006807;amino acid biosynthetic process#GO:0008652;alpha-amino acid metabolic process#GO:1901605;small molecule biosynthetic process#GO:0044283;carboxylic acid metabolic process#GO:0019752;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 epimerase/racemase#PC00096 Isoleucine biosynthesis#P02748>Threonine dehydratase#P02995 CIOIN|Ensembl=ENSCING00000009985.3|UniProtKB=F6QMD4 F6QMD4 LOC100176045 PTHR24343:SF0 SERINE/THREONINE KINASE SERINE_THREONINE-PROTEIN KINASE NIM1 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;nitrogen compound metabolic process#GO:0006807;biological regulation#GO:0065007;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000005958.2|UniProtKB=F6WF75 F6WF75 PTHR10334:SF554 CYSTEINE-RICH SECRETORY PROTEIN-RELATED AT04879P-RELATED extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 defense/immunity protein#PC00090 CIOIN|Ensembl=ENSCING00000005393.3|UniProtKB=F6UB61 F6UB61 PTHR23277:SF108 NECTIN-RELATED FASCICLIN-3 cell-cell adhesion via plasma-membrane adhesion molecules#GO:0098742;heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules#GO:0007157;cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987;homophilic cell adhesion via plasma membrane adhesion molecules#GO:0007156 cell junction#GO:0030054;adherens junction#GO:0005912;cellular anatomical entity#GO:0110165;cell-cell junction#GO:0005911;anchoring junction#GO:0070161 cell adhesion molecule#PC00069 CIOIN|Ensembl=ENSCING00000023073.1|UniProtKB=H2XJN3 H2XJN3 PTHR42919:SF8 N-ALPHA-ACETYLTRANSFERASE N-ALPHA-ACETYLTRANSFERASE 50 acetyltransferase#PC00038 CIOIN|Ensembl=ENSCING00000009196.3|UniProtKB=F6YLW1 F6YLW1 LOC100176733 PTHR14418:SF5 CONDENSIN COMPLEX SUBUNIT 3-RELATED CONDENSIN COMPLEX SUBUNIT 3 nuclear chromosome segregation#GO:0098813;sister chromatid segregation#GO:0000819;nuclear division#GO:0000280;cell cycle process#GO:0022402;chromosome condensation#GO:0030261;cellular component organization#GO:0016043;cellular process#GO:0009987;mitotic cell cycle process#GO:1903047;chromosome segregation#GO:0007059;mitotic chromosome condensation#GO:0007076;cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;chromosome organization#GO:0051276;organelle organization#GO:0006996;cell cycle#GO:0007049;mitotic nuclear division#GO:0140014;organelle fission#GO:0048285;mitotic sister chromatid segregation#GO:0000070 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;chromosome#GO:0005694;condensed chromosome#GO:0000793;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000006720.3|UniProtKB=F7A7M7 F7A7M7 LOC100176001 PTHR21281:SF0 CYTOCHROME B5 DOMAIN-CONTAINING PROTEIN 1 CYTOCHROME B5 DOMAIN-CONTAINING PROTEIN 1 CIOIN|Ensembl=ENSCING00000002681.1|UniProtKB=F6XPY9 F6XPY9 PTHR12242:SF1 OS02G0130600 PROTEIN-RELATED MYND-TYPE DOMAIN-CONTAINING PROTEIN cellular anatomical entity#GO:0110165;membrane#GO:0016020 CIOIN|Ensembl=ENSCING00000014236.2|UniProtKB=F6XZL0 F6XZL0 LOC100182431 PTHR11652:SF1 30S RIBOSOMAL PROTEIN S12 FAMILY MEMBER MITOCHONDRIAL RIBOSOMAL PROTEIN, SMALL structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000019896.1|UniProtKB=H2XV31 H2XV31 LOC100185381 PTHR28595:SF1 39S RIBOSOMAL PROTEIN L54, MITOCHONDRIAL LARGE RIBOSOMAL SUBUNIT PROTEIN ML54 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;mitochondrial large ribosomal subunit#GO:0005762;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;mitochondrial ribosome#GO:0005761;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;ribosomal subunit#GO:0044391;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;organellar ribosome#GO:0000313;protein-containing complex#GO:0032991;large ribosomal subunit#GO:0015934;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;ribosome#GO:0005840;mitochondrial protein-containing complex#GO:0098798 ribosomal protein#PC00202;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000018470.1|UniProtKB=H2Y159 H2Y159 LOC108949271 PTHR10036:SF25 CD59 GLYCOPROTEIN HEP21 PROTEIN CIOIN|Ensembl=ENSCING00000021659.1|UniProtKB=H2XR11 H2XR11 LOC100175406 PTHR28573:SF1 SPINDLE AND KINETOCHORE-ASSOCIATED PROTEIN 1 SPINDLE AND KINETOCHORE-ASSOCIATED PROTEIN 1 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 regulation of biological process#GO:0050789;regulation of microtubule-based process#GO:0032886;regulation of cytoskeleton organization#GO:0051493;cell division#GO:0051301;mitotic cell cycle#GO:0000278;regulation of cellular process#GO:0050794;regulation of organelle organization#GO:0033043;regulation of microtubule cytoskeleton organization#GO:0070507;biological regulation#GO:0065007;cell cycle process#GO:0022402;cell cycle#GO:0007049;regulation of cellular component organization#GO:0051128;regulation of microtubule polymerization or depolymerization#GO:0031110;cellular process#GO:0009987;chromosome segregation#GO:0007059 supramolecular complex#GO:0099080;outer kinetochore#GO:0000940;spindle microtubule#GO:0005876;kinetochore#GO:0000776;condensed chromosome, centromeric region#GO:0000779;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;mitotic spindle#GO:0072686;chromosome#GO:0005694;microtubule cytoskeleton#GO:0015630;chromosomal region#GO:0098687;cytoskeleton#GO:0005856;spindle#GO:0005819;microtubule#GO:0005874 CIOIN|Ensembl=ENSCING00000022049.1|UniProtKB=H2XYB2 H2XYB2 LOC100176975 PTHR21304:SF0 MICOS COMPLEX SUBUNIT MIC10 MICOS COMPLEX SUBUNIT MIC10 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000020258.1|UniProtKB=H2XVS0 H2XVS0 LOC100180652 PTHR23320:SF158 MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MS4A -RELATED CREB-BINDING PROTEIN-LIKE ISOFORM X1 transporter#PC00227 CIOIN|Ensembl=ENSCING00000006030.3|UniProtKB=F6ZZL8 F6ZZL8 PTHR12587:SF20 LAR INTERACTING PROTEIN LIP -RELATED PROTEIN LIPRIN-ALPHA, ISOFORM E cellular component organization or biogenesis#GO:0071840;synapse organization#GO:0050808;cellular component organization#GO:0016043;cellular process#GO:0009987;cell junction organization#GO:0034330 cell junction#GO:0030054;presynapse#GO:0098793;synapse#GO:0045202;cellular anatomical entity#GO:0110165;presynaptic active zone#GO:0048786 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000006703.3|UniProtKB=F7ARF4 F7ARF4 PTHR24291:SF189 CYTOCHROME P450 FAMILY 4 CYTOCHROME P450 4C3-RELATED oxygenase#PC00177;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000024766.1|UniProtKB=H2XZR9 H2XZR9 PTHR14949:SF57 EGF-LIKE-DOMAIN, MULTIPLE 7, 8 EGF-LIKE DOMAIN-CONTAINING PROTEIN protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 anatomical structure development#GO:0048856;developmental process#GO:0032502 cell surface#GO:0009986;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 CIOIN|Ensembl=ENSCING00000005004.3|UniProtKB=F6TXS7 F6TXS7 PTHR11675:SF131 N-ACETYLGALACTOSAMINYLTRANSFERASE POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE 9-RELATED transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;UDP-glycosyltransferase activity#GO:0008194 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;protein O-linked glycosylation#GO:0006493;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000019187.1|UniProtKB=H2XS69 H2XS69 PTHR35968:SF1 CHROMOSOME 6 C6ORF201 HOMOLOG TESTIS EXPRESSED PROTEIN 56 CIOIN|Ensembl=ENSCING00000020499.1|UniProtKB=H2XXS6 H2XXS6 PTHR43764:SF1 MOLYBDENUM COFACTOR BIOSYNTHESIS MOLYBDOPTERIN MOLYBDOTRANSFERASE CIOIN|Ensembl=ENSCING00000004079.3|UniProtKB=F6Z1B8 F6Z1B8 PTHR44154:SF1 QUINONE OXIDOREDUCTASE QUINONE OXIDOREDUCTASE oxidoreductase#PC00176 Huntington disease#P00029>PIG3#G01535 CIOIN|Ensembl=ENSCING00000020415.1|UniProtKB=H2XRL2 H2XRL2 PTHR20003:SF7 GLYCOPROTEIN-RELATED SGNH DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000021124.1|UniProtKB=H2XS44 H2XS44 PTHR13723:SF281 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE PAPILIN metalloprotease#PC00153;protease#PC00190 CIOIN|Ensembl=ENSCING00000007384.3|UniProtKB=F6ULQ2 F6ULQ2 LOC100176570 PTHR23423:SF10 ORGANIC SOLUTE TRANSPORTER-RELATED TRANSMEMBRANE PROTEIN 184C localization#GO:0051179;establishment of localization#GO:0051234;transport#GO:0006810 cellular anatomical entity#GO:0110165;membrane#GO:0016020 transporter#PC00227 CIOIN|Ensembl=ENSCING00000005928.3|UniProtKB=F6ZHC8 F6ZHC8 LOC100181046 PTHR24241:SF188 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR GASTRIN_CHOLECYSTOKININ TYPE B RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;binding#GO:0005488;peptide binding#GO:0042277;transmembrane signaling receptor activity#GO:0004888;amide binding#GO:0033218 response to organic substance#GO:0010033;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to endogenous stimulus#GO:0009719;cellular response to hormone stimulus#GO:0032870;response to hormone#GO:0009725;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 CIOIN|Ensembl=ENSCING00000005093.2|UniProtKB=F6WKT2 F6WKT2 PTHR10404:SF81 N-ACETYLATED-ALPHA-LINKED ACIDIC DIPEPTIDASE N-ACETYLATED ALPHA-LINKED ACIDIC DIPEPTIDASE 2 hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;carboxypeptidase activity#GO:0004180 metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000003706.3|UniProtKB=F6XHN7 F6XHN7 LOC100183977 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE SSU-1 sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824 cellular metabolic process#GO:0044237;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000007464.3|UniProtKB=Q4H363 Q4H363 Ci-Mox PTHR24328:SF7 HOMEOBOX PROTEIN MOX BUTTONLESS sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 CIOIN|Ensembl=ENSCING00000004162.3|UniProtKB=F7BQ30 F7BQ30 PTHR11528:SF44 HEAT SHOCK PROTEIN 90 FAMILY MEMBER HEAT SHOCK PROTEIN 75 KDA, MITOCHONDRIAL-RELATED enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;unfolded protein binding#GO:0051082;binding#GO:0005488;kinase binding#GO:0019900 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein folding#GO:0006457;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 envelope#GO:0031975;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;organelle membrane#GO:0031090;organelle inner membrane#GO:0019866;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227 Hsp90 family chaperone#PC00028 CIOIN|Ensembl=ENSCING00000024983.1|UniProtKB=H2XKD5 H2XKD5 LOC100183335 PTHR11141:SF0 PROTEIN TRANSPORT PROTEIN SEC23 PROTEIN TRANSPORT PROTEIN SEC23 nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;membrane organization#GO:0061024;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;COPII-coated vesicle budding#GO:0090114;establishment of localization in cell#GO:0051649;vesicle organization#GO:0016050;intracellular transport#GO:0046907 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;ER to Golgi transport vesicle membrane#GO:0012507;endoplasmic reticulum exit site#GO:0070971;COPII-coated ER to Golgi transport vesicle#GO:0030134;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;coated vesicle#GO:0030135;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;vesicle coat#GO:0030120;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;transport vesicle membrane#GO:0030658;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;membrane coat#GO:0030117;coated vesicle membrane#GO:0030662;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;transport vesicle#GO:0030133;coated membrane#GO:0048475;cytoplasmic vesicle membrane#GO:0030659;endoplasmic reticulum#GO:0005783 vesicle coat protein#PC00235 CIOIN|Ensembl=ENSCING00000019772.1|UniProtKB=H2XUK5 H2XUK5 LOC100181314 PTHR10762:SF2 DIPHTHAMIDE BIOSYNTHESIS PROTEIN 2-(3-AMINO-3-CARBOXYPROPYL)HISTIDINE SYNTHASE SUBUNIT 2 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;primary metabolic process#GO:0044238 CIOIN|Ensembl=ENSCING00000002989.3|UniProtKB=F6QBL6 F6QBL6 PTHR10082:SF60 INTEGRIN BETA SUBUNIT INTEGRIN BETA-PS cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;integrin binding#GO:0005178;binding#GO:0005488;signaling receptor binding#GO:0005102 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cell adhesion mediated by integrin#GO:0033627;cell-cell adhesion#GO:0098609;cell motility#GO:0048870;cell adhesion#GO:0007155;cell communication#GO:0007154;cell-substrate adhesion#GO:0031589;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cell-matrix adhesion#GO:0007160;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;integrin-mediated signaling pathway#GO:0007229;cell migration#GO:0016477;signaling#GO:0023052 receptor complex#GO:0043235;membrane protein complex#GO:0098796;cell surface#GO:0009986;protein-containing complex#GO:0032991;plasma membrane signaling receptor complex#GO:0098802;anchoring junction#GO:0070161;plasma membrane protein complex#GO:0098797;focal adhesion#GO:0005925;cell junction#GO:0030054;cell-substrate junction#GO:0030055;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cell adhesion molecule#PC00069;integrin#PC00126 Integrin signalling pathway#P00034>Integrin beta#P00931 CIOIN|Ensembl=ENSCING00000021102.1|UniProtKB=H2XP92 H2XP92 LOC104265386 PTHR23306:SF3 TUMOR SUSCEPTIBILITY GENE 101 PROTEIN-RELATED TUMOR SUPPRESSOR PROTEIN 101 protein binding#GO:0005515;ubiquitin-like protein binding#GO:0032182;binding#GO:0005488;ubiquitin binding#GO:0043130 localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;vacuolar transport#GO:0007034;transport#GO:0006810;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;endosome to lysosome transport#GO:0008333;cellular process#GO:0009987;lysosomal transport#GO:0007041 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endosome membrane#GO:0010008;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;ESCRT I complex#GO:0000813;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle membrane#GO:0030659 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000000546.3|UniProtKB=F6QB20 F6QB20 LOC100178709 PTHR11588:SF486 TUBULIN TUBULIN ALPHA-4 CHAIN carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;structural molecule activity#GO:0005198;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167;structural constituent of cytoskeleton#GO:0005200 cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;microtubule-based process#GO:0007017;organelle organization#GO:0006996;microtubule cytoskeleton organization#GO:0000226;cytoskeleton organization#GO:0007010;cell cycle#GO:0007049;cellular component organization#GO:0016043;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622 tubulin#PC00228;microtubule or microtubule-binding cytoskeletal protein#PC00157 CIOIN|Ensembl=ENSCING00000005593.3|UniProtKB=F6U3E1 F6U3E1 PTHR23159:SF31 CENTROSOMAL PROTEIN 2 CENTROSOME-ASSOCIATED PROTEIN CEP250 ISOFORM X1 chromatin/chromatin-binding, or -regulatory protein#PC00077 CIOIN|Ensembl=ENSCING00000006798.4|UniProtKB=F6VD90 F6VD90 PTHR46520:SF1 SERINE BETA-LACTAMASE-LIKE PROTEIN LACTB, MITOCHONDRIAL SERINE BETA-LACTAMASE-LIKE PROTEIN LACTB, MITOCHONDRIAL hydrolase activity#GO:0016787;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;biological regulation#GO:0065007;organonitrogen compound metabolic process#GO:1901564;regulation of lipid metabolic process#GO:0019216;protein metabolic process#GO:0019538;regulation of metabolic process#GO:0019222;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000023341.1|UniProtKB=H2XUY8 H2XUY8 LOC100183220 PTHR21676:SF1 PROTEIN STUM PROTEIN STUM HOMOLOG CIOIN|Ensembl=ENSCING00000003450.3|UniProtKB=F6WXR3 F6WXR3 PTHR22589:SF31 CARNITINE O-ACYLTRANSFERASE CARNITINE O-PALMITOYLTRANSFERASE palmitoyltransferase activity#GO:0016409;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;O-acyltransferase activity#GO:0008374 oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;fatty acid metabolic process#GO:0006631;nitrogen compound metabolic process#GO:0006807;cellular modified amino acid metabolic process#GO:0006575;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transferase#PC00220;acyltransferase#PC00042;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000019158.1|UniProtKB=H2XTI6 H2XTI6 PTHR19444:SF13 UNC-93 RELATED PROTEIN UNC-93 HOMOLOG A membrane-bound signaling molecule#PC00152 CIOIN|Ensembl=ENSCING00000015093.2|UniProtKB=F6ZIG5 F6ZIG5 PTHR12231:SF253 CTX-RELATED TYPE I TRANSMEMBRANE PROTEIN DPR-INTERACTING PROTEIN ETA, ISOFORM B-RELATED immunoglobulin superfamily cell adhesion molecule#PC00125 CIOIN|Ensembl=ENSCING00000006961.3|UniProtKB=F6SZ48 F6SZ48 PTHR24023:SF1112 COLLAGEN ALPHA COL_CUTICLE_N DOMAIN-CONTAINING PROTEIN-RELATED structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;external encapsulating structure organization#GO:0045229;extracellular matrix organization#GO:0030198 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;extracellular region#GO:0005576 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 Integrin signalling pathway#P00034>Collagen#P00922 CIOIN|Ensembl=ENSCING00000001270.3|UniProtKB=A0A1W5BFR6 A0A1W5BFR6 hex PTHR24324:SF5 HOMEOBOX PROTEIN HHEX HEMATOPOIETICALLY-EXPRESSED HOMEOBOX PROTEIN HHEX sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 homeodomain transcription factor#PC00119 CIOIN|Ensembl=ENSCING00000008835.3|UniProtKB=F6YEB1 F6YEB1 PTHR12756:SF11 CYTOSOLIC CARBOXYPEPTIDASE CYTOSOLIC CARBOXYPEPTIDASE 1 metalloprotease#PC00153;protease#PC00190 CIOIN|Ensembl=ENSCING00000020063.1|UniProtKB=H2XPD4 H2XPD4 LOC101242069 PTHR23301:SF0 CHITIN BINDING PERITROPHIN-A CHITIN-BINDING TYPE-2 DOMAIN-CONTAINING PROTEIN-RELATED CIOIN|Ensembl=ENSCING00000002661.3|UniProtKB=F6YDG1 F6YDG1 PTHR45957:SF1 ANAPHASE-PROMOTING COMPLEX SUBUNIT 2 ANAPHASE-PROMOTING COMPLEX SUBUNIT 2 regulation of chromosome segregation#GO:0051983;mitotic cell cycle phase transition#GO:0044772;macromolecule modification#GO:0043412;cell cycle process#GO:0022402;protein modification process#GO:0036211;regulation of cellular component organization#GO:0051128;post-translational protein modification#GO:0043687;mitotic cell cycle process#GO:1903047;regulation of biological process#GO:0050789;mitotic cell cycle#GO:0000278;nitrogen compound metabolic process#GO:0006807;protein polyubiquitination#GO:0000209;protein K11-linked ubiquitination#GO:0070979;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;regulation of chromosome organization#GO:0033044;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;regulation of organelle organization#GO:0033043;organonitrogen compound metabolic process#GO:1901564;cellular process#GO:0009987;cell cycle phase transition#GO:0044770;regulation of cell cycle process#GO:0010564;primary metabolic process#GO:0044238;metaphase/anaphase transition of cell cycle#GO:0044784;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;cell cycle#GO:0007049;regulation of sister chromatid segregation#GO:0033045;metaphase/anaphase transition of mitotic cell cycle#GO:0007091 ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cullin-RING ubiquitin ligase complex#GO:0031461;catalytic complex#GO:1902494;transferase complex#GO:1990234;anaphase-promoting complex#GO:0005680;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;nuclear ubiquitin ligase complex#GO:0000152;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 Cell cycle#P00013>APC#P00481 CIOIN|Ensembl=ENSCING00000011628.2|UniProtKB=A0A1W2WM83 A0A1W2WM83 LOC100180455 PTHR12538:SF0 40S RIBOSOMAL PROTEIN S26 40S RIBOSOMAL PROTEIN S26 structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;RNA binding#GO:0003723;structural molecule activity#GO:0005198;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic small ribosomal subunit#GO:0022627;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;small ribosomal subunit#GO:0015935;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;ribosomal subunit#GO:0044391 ribosomal protein#PC00202;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000021149.1|UniProtKB=H2XMQ5 H2XMQ5 PTHR11157:SF17 FATTY ACID ACYL TRANSFERASE-RELATED ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN 6 acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824 organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;monocarboxylic acid biosynthetic process#GO:0072330;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;organic acid metabolic process#GO:0006082;membrane lipid biosynthetic process#GO:0046467;sphingolipid metabolic process#GO:0006665;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;fatty acid metabolic process#GO:0006631;membrane lipid metabolic process#GO:0006643;nitrogen compound metabolic process#GO:0006807;small molecule biosynthetic process#GO:0044283;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;sphingolipid biosynthetic process#GO:0030148;fatty acid biosynthetic process#GO:0006633;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 acyltransferase#PC00042 CIOIN|Ensembl=ENSCING00000011440.2|UniProtKB=F7AD34 F7AD34 LOC100184729 PTHR10907:SF47 REGUCALCIN REGUCALCIN cation binding#GO:0043169;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167 organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;monosaccharide metabolic process#GO:0005996;heterocycle metabolic process#GO:0046483;carbohydrate biosynthetic process#GO:0016051;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;organic cyclic compound metabolic process#GO:1901360;small molecule biosynthetic process#GO:0044283;carboxylic acid metabolic process#GO:0019752;carbohydrate metabolic process#GO:0005975;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 esterase#PC00097 CIOIN|Ensembl=ENSCING00000009071.3|UniProtKB=F6QIR4 F6QIR4 LOC100175164 PTHR24356:SF210 SERINE/THREONINE-PROTEIN KINASE SERINE_THREONINE-PROTEIN KINASE N transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular process#GO:0009987;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Alzheimer disease-amyloid secretase pathway#P00003>PKC#P00109;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>PKC#P01074 CIOIN|Ensembl=ENSCING00000005875.3|UniProtKB=F6T4Y7 F6T4Y7 PTHR11731:SF193 PROTEASE FAMILY S9B,C DIPEPTIDYL-PEPTIDASE IV-RELATED DIPEPTIDYL PEPTIDASE 9 hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;metabolic process#GO:0008152;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704 serine protease#PC00203;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000018938.1|UniProtKB=H2XNC4 H2XNC4 PTHR47266:SF31 ENDONUCLEASE-RELATED RNA-DIRECTED DNA POLYMERASE CIOIN|Ensembl=ENSCING00000000089.3|UniProtKB=F6TS15 F6TS15 PTHR22619:SF1 ZINC FINGER SWIM DOMAIN CONTAINING PROTEIN 4, 5, 6 ZINC FINGER SWIM DOMAIN-CONTAINING PROTEIN 8 intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;cullin-RING ubiquitin ligase complex#GO:0031461;catalytic complex#GO:1902494;transferase complex#GO:1990234 CIOIN|Ensembl=ENSCING00000007266.3|UniProtKB=F6THW7 F6THW7 LOC100176985 PTHR11132:SF240 SOLUTE CARRIER FAMILY 35 UDP-SUGAR TRANSPORTER UST74C carbohydrate derivative transmembrane transporter activity#GO:1901505;secondary active transmembrane transporter activity#GO:0015291;antiporter activity#GO:0015297;transmembrane transporter activity#GO:0022857;nucleobase-containing compound transmembrane transporter activity#GO:0015932;nucleotide-sugar transmembrane transporter activity#GO:0005338;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215 localization#GO:0051179;organic substance transport#GO:0071702;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;nucleobase-containing compound transport#GO:0015931;nucleotide-sugar transmembrane transport#GO:0015780;transport#GO:0006810;nitrogen compound transport#GO:0071705;cellular process#GO:0009987;carbohydrate derivative transport#GO:1901264 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000002963.3|UniProtKB=F6R3V0 F6R3V0 PTHR13720:SF50 WD-40 REPEAT PROTEIN ECHINODERM MICROTUBULE-ASSOCIATED PROTEIN-LIKE 2 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cellular process#GO:0009987;microtubule-based process#GO:0007017;organelle organization#GO:0006996 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;mitotic spindle#GO:0072686;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;spindle#GO:0005819;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;microtubule or microtubule-binding cytoskeletal protein#PC00157 CIOIN|Ensembl=ENSCING00000021895.1|UniProtKB=H2XZ54 H2XZ54 PTHR11800:SF2 DNA-DIRECTED RNA POLYMERASE DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB3 catalytic activity, acting on RNA#GO:0140098;5'-3' RNA polymerase activity#GO:0034062;transferase activity#GO:0016740;DNA-directed 5'-3' RNA polymerase activity#GO:0003899;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;RNA polymerase activity#GO:0097747;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring phosphorus-containing groups#GO:0016772 RNA metabolism protein#PC00031;DNA-directed RNA polymerase#PC00019 Transcription regulation by bZIP transcription factor#P00055>RNA Polymerase II#P01388;General transcription regulation#P00023>RNA Polymerase II#P00660 CIOIN|Ensembl=ENSCING00000022976.1|UniProtKB=H2Y0X8 H2Y0X8 LOC100181843 PTHR24299:SF21 CYTOCHROME P450 FAMILY 1 OS09G0441600 PROTEIN oxygenase#PC00177;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000012500.2|UniProtKB=F6S5X9 F6S5X9 PTHR10209:SF881 OXIDOREDUCTASE, 2OG-FE II OXYGENASE FAMILY PROTEIN FI07970P-RELATED oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000022806.1|UniProtKB=H2XW94 H2XW94 sir2-a PTHR11085:SF7 NAD-DEPENDENT PROTEIN DEACYLASE SIRTUIN-5, MITOCHONDRIAL-RELATED NAD-DEPENDENT PROTEIN DEACETYLASE nucleotide binding#GO:0000166;histone modifying activity#GO:0140993;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;deacetylase activity#GO:0019213;histone deacetylase activity#GO:0004407;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;anion binding#GO:0043168;catalytic activity, acting on a protein#GO:0140096 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000001836.3|UniProtKB=Q4H2U9 Q4H2U9 Ci-RXR PTHR24083:SF103 NUCLEAR HORMONE RECEPTOR PROTEIN ULTRASPIRACLE cis-regulatory region sequence-specific DNA binding#GO:0000987;signaling receptor activity#GO:0038023;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular transducer activity#GO:0060089;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA metabolic process#GO:0051252;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;anatomical structure development#GO:0048856;biological regulation#GO:0065007;positive regulation of RNA metabolic process#GO:0051254;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C4 zinc finger nuclear receptor#PC00169;zinc finger transcription factor#PC00244 CIOIN|Ensembl=ENSCING00000002353.3|UniProtKB=F6V6X8 F6V6X8 PTHR24347:SF412 SERINE/THREONINE-PROTEIN KINASE SERINE_THREONINE-PROTEIN KINASE H1 HOMOLOG-RELATED non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CaMK#P00847;Ionotropic glutamate receptor pathway#P00037>CaMKII#P01023 CIOIN|Ensembl=ENSCING00000009084.3|UniProtKB=F6QEI5 F6QEI5 PTHR10194:SF142 RAS GTPASE-ACTIVATING PROTEINS NEUROFIBROMIN G-protein modulator#PC00022;protein-binding activity modulator#PC00095;GTPase-activating protein#PC00257 EGF receptor signaling pathway#P00018>GAP#P00546 CIOIN|Ensembl=ENSCING00000009626.3|UniProtKB=F6ZUQ2 F6ZUQ2 PTHR12400:SF21 INOSITOL POLYPHOSPHATE KINASE KINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301 organic hydroxy compound metabolic process#GO:1901615;organophosphate biosynthetic process#GO:0090407;alcohol biosynthetic process#GO:0046165;cellular metabolic process#GO:0044237;alcohol metabolic process#GO:0006066;organic hydroxy compound biosynthetic process#GO:1901617;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;organophosphate metabolic process#GO:0019637;small molecule biosynthetic process#GO:0044283;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 kinase#PC00137 CIOIN|Ensembl=ENSCING00000000139.3|UniProtKB=F7A0P0 F7A0P0 PTHR24350:SF0 SERINE/THREONINE-PROTEIN KINASE IAL-RELATED AURORA KINASE mitotic spindle organization#GO:0007052;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;cellular component organization#GO:0016043;microtubule cytoskeleton organization involved in mitosis#GO:1902850;regulation of cell division#GO:0051302;cellular process#GO:0009987;mitotic cell cycle process#GO:1903047;regulation of cell cycle process#GO:0010564;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;microtubule-based process#GO:0007017;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;biological regulation#GO:0065007;cell cycle#GO:0007049;cytoskeleton organization#GO:0007010;regulation of cell cycle#GO:0051726;spindle organization#GO:0007051;regulation of cytokinesis#GO:0032465 supramolecular complex#GO:0099080;spindle midzone#GO:0051233;spindle microtubule#GO:0005876;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;microtubule#GO:0005874;spindle#GO:0005819 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000008369.3|UniProtKB=F6YWP5 F6YWP5 LOC100181233 PTHR10801:SF0 24-DEHYDROCHOLESTEROL REDUCTASE DELTA(24)-STEROL REDUCTASE reductase#PC00198;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000005243.4|UniProtKB=F6XUV4 F6XUV4 PTHR10629:SF52 CYTOSINE-SPECIFIC METHYLTRANSFERASE DNA (CYTOSINE-5)-METHYLTRANSFERASE 1 DNA methyltransferase#PC00013 CIOIN|Ensembl=ENSCING00000002615.3|UniProtKB=F7B2Y0 F7B2Y0 LOC100178084 PTHR21017:SF19 NIPSNAP-RELATED PROTEIN NIPSNAP HOMOLOG 3B cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000006868.3|UniProtKB=F6ZCY4 F6ZCY4 PTHR12783:SF5 RALA BINDING PROTEIN 1 RALBP1 RALA-BINDING PROTEIN 1 G-protein modulator#PC00022;protein-binding activity modulator#PC00095;GTPase-activating protein#PC00257 CIOIN|Ensembl=ENSCING00000005870.3|UniProtKB=F6TRZ9 F6TRZ9 akr1a PTHR11732:SF175 ALDO/KETO REDUCTASE NADP-DEPENDENT OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 reductase#PC00198;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000004285.3|UniProtKB=F6UGJ2 F6UGJ2 PTHR11675:SF101 N-ACETYLGALACTOSAMINYLTRANSFERASE POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE 5 transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;UDP-glycosyltransferase activity#GO:0008194 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;protein O-linked glycosylation#GO:0006493;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000007642.3|UniProtKB=F6WI49 F6WI49 PTHR11732:SF506 ALDO/KETO REDUCTASE ALDO-KETO REDUCTASE 1B, ISOFORM C-RELATED oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 reductase#PC00198;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000003985.3|UniProtKB=F6S8T2 F6S8T2 PTHR24418:SF384 TYROSINE-PROTEIN KINASE ACTIVATED CDC42 KINASE 1 protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 non-receptor tyrosine protein kinase#PC00168 CIOIN|Ensembl=ENSCING00000005828.3|UniProtKB=F6VVA7 F6VVA7 PTHR10390:SF33 HOMEOBOX PROTEIN SIX PROTEIN OPTIX sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 CIOIN|Ensembl=ENSCING00000010675.3|UniProtKB=F6SD13 F6SD13 PTHR12010:SF2 40S RIBOSOMAL PROTEIN S29 40S RIBOSOMAL PROTEIN S29 cation binding#GO:0043169;structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198;small molecule binding#GO:0036094;zinc ion binding#GO:0008270;binding#GO:0005488;transition metal ion binding#GO:0046914;metal ion binding#GO:0046872;ion binding#GO:0043167 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cytoplasmic translation#GO:0002181;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic small ribosomal subunit#GO:0022627;cytosol#GO:0005829;small ribosomal subunit#GO:0015935;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000008008.3|UniProtKB=F6VHJ0 F6VHJ0 PTHR48106:SF18 QUINONE OXIDOREDUCTASE PIG3-RELATED QUINONE OXIDOREDUCTASE PIG3 nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;oxidoreductase activity, acting on NAD(P)H#GO:0016651;ion binding#GO:0043167;anion binding#GO:0043168;oxidoreductase activity#GO:0016491 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 Huntington disease#P00029>PIG3#G01535 CIOIN|Ensembl=ENSCING00000013381.2|UniProtKB=F6YDT6 F6YDT6 LOC100181515 PTHR19423:SF1 SH3 DOMAIN-BINDING PROTEIN 5 SH3 DOMAIN-BINDING PROTEIN 5 enzyme inhibitor activity#GO:0004857;protein kinase regulator activity#GO:0019887;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;protein kinase inhibitor activity#GO:0004860 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;signaling#GO:0023052 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000009423.3|UniProtKB=F6TLL4 F6TLL4 LOC100176863 PTHR11558:SF11 SPERMIDINE/SPERMINE SYNTHASE SPERMIDINE SYNTHASE transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000008141.3|UniProtKB=F6VGF9 F6VGF9 LOC100184400 PTHR13408:SF0 DNA-DIRECTED RNA POLYMERASE III DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC4 cellular aromatic compound metabolic process#GO:0006725;DNA-templated transcription#GO:0006351;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;transcription by RNA polymerase III#GO:0006383;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;RNA biosynthetic process#GO:0032774;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;ncRNA transcription#GO:0098781;aromatic compound biosynthetic process#GO:0019438;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;DNA-directed RNA polymerase complex#GO:0000428;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;RNA polymerase III complex#GO:0005666;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 RNA metabolism protein#PC00031;DNA-directed RNA polymerase#PC00019 CIOIN|Ensembl=ENSCING00000001763.3|UniProtKB=F7A3X7 F7A3X7 LOC100184020 PTHR12840:SF1 NADH-UBIQUINONE OXIDOREDUCTASE ASHI SUBUNIT NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 8, MITOCHONDRIAL envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;respiratory chain complex#GO:0098803;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transporter complex#GO:1990351;oxidoreductase complex#GO:1990204;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;respirasome#GO:0070469;mitochondrial respiratory chain complex I#GO:0005747;protein-containing complex#GO:0032991;mitochondrial envelope#GO:0005740;inner mitochondrial membrane protein complex#GO:0098800;transmembrane transporter complex#GO:1902495;mitochondrial respirasome#GO:0005746;membrane-bounded organelle#GO:0043227;respiratory chain complex I#GO:0045271;NADH dehydrogenase complex#GO:0030964;mitochondrial protein-containing complex#GO:0098798 oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000022606.1|UniProtKB=H2XVW7 H2XVW7 LOC100185513 PTHR31698:SF8 LYSOZYME G FAMILY MEMBER LYSOZYME G-RELATED CIOIN|Ensembl=ENSCING00000005732.3|UniProtKB=F6U222 F6U222 PTHR22589:SF16 CARNITINE O-ACYLTRANSFERASE CARNITINE O-PALMITOYLTRANSFERASE 2, MITOCHONDRIAL palmitoyltransferase activity#GO:0016409;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;O-acyltransferase activity#GO:0008374 oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;lipid oxidation#GO:0034440;cellular metabolic process#GO:0044237;lipid catabolic process#GO:0016042;lipid modification#GO:0030258;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;fatty acid catabolic process#GO:0009062;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;fatty acid metabolic process#GO:0006631;small molecule catabolic process#GO:0044282;fatty acid beta-oxidation#GO:0006635;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;cellular lipid metabolic process#GO:0044255;cellular lipid catabolic process#GO:0044242;carboxylic acid metabolic process#GO:0019752;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;monocarboxylic acid catabolic process#GO:0072329 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transferase#PC00220;acyltransferase#PC00042;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000023539.1|UniProtKB=H2XY76 H2XY76 LOC100177325 PTHR47979:SF24 DRAB11-RELATED SMALL MONOMERIC GTPASE GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;anion binding#GO:0043168;ion binding#GO:0043167 localization#GO:0051179;regulation of biological process#GO:0050789;regulation of endocytosis#GO:0030100;regulation of transport#GO:0051049;establishment of localization#GO:0051234;regulation of cellular process#GO:0050794;transport#GO:0006810;biological regulation#GO:0065007;regulation of localization#GO:0032879;vesicle-mediated transport#GO:0016192;regulation of cellular component organization#GO:0051128;cellular process#GO:0009987;regulation of vesicle-mediated transport#GO:0060627 cytoplasm#GO:0005737;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular vesicle#GO:0097708;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 small GTPase#PC00208 CIOIN|Ensembl=ENSCING00000013280.2|UniProtKB=F7BLR9 F7BLR9 PTHR24327:SF41 HOMEOBOX PROTEIN BRAIN-SPECIFIC HOMEOBOX PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 homeodomain transcription factor#PC00119 CIOIN|Ensembl=ENSCING00000005668.3|UniProtKB=F6Y178 F6Y178 PTHR11958:SF63 SODIUM/DICARBOXYLATE SYMPORTER-RELATED AMINO ACID TRANSPORTER primary active transporter#PC00068;transporter#PC00227 Ionotropic glutamate receptor pathway#P00037>EAAT#P01011;Metabotropic glutamate receptor group III pathway#P00039>EAAT#P01036 CIOIN|Ensembl=ENSCING00000013493.2|UniProtKB=F7B262 F7B262 PTHR11388:SF157 ORGANIC ANION TRANSPORTER SOLUTE CARRIER ORGANIC ANION TRANSPORTER FAMILY MEMBER 2A1-LIKE secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 localization#GO:0051179;organic substance transport#GO:0071702;establishment of localization#GO:0051234;organic anion transport#GO:0015711;transport#GO:0006810 basal plasma membrane#GO:0009925;basolateral plasma membrane#GO:0016323;plasma membrane region#GO:0098590;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;basal part of cell#GO:0045178;plasma membrane#GO:0005886 transporter#PC00227 CIOIN|Ensembl=ENSCING00000002597.3|UniProtKB=F7B2Q7 F7B2Q7 LOC100179599 PTHR11635:SF152 CAMP-DEPENDENT PROTEIN KINASE REGULATORY CHAIN CAMP-DEPENDENT PROTEIN KINASE TYPE I REGULATORY SUBUNIT-RELATED cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 kinase modulator#PC00140 Metabotropic glutamate receptor group III pathway#P00039>PKA#P01035;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>PKA#P01075;Cell cycle#P00013>Protein kinase subunit#P00482;GABA-B receptor II signaling#P05731>PKA#P05752;5HT1 type receptor mediated signaling pathway#P04373>PKA#P04403;Enkephalin release#P05913>PKA#P05972;Histamine H2 receptor mediated signaling pathway#P04386>PKA#P04491;Dopamine receptor mediated signaling pathway#P05912>PKA#P05946;Transcription regulation by bZIP transcription factor#P00055>PKA#P01384;Beta2 adrenergic receptor signaling pathway#P04378>PKA#P04444;Metabotropic glutamate receptor group II pathway#P00040>PKA#P01050;Hedgehog signaling pathway#P00025>PKA#P00682;Beta1 adrenergic receptor signaling pathway#P04377>PKA#P04437;Metabotropic glutamate receptor group I pathway#P00041>PKA#P01059;Endothelin signaling pathway#P00019>PKA#P00570 CIOIN|Ensembl=ENSCING00000000839.3|UniProtKB=F6R1I0 F6R1I0 PTHR10218:SF329 GTP-BINDING PROTEIN ALPHA SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN G(Q) SUBUNIT ALPHA GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;ribonucleoside triphosphate phosphatase activity#GO:0017111;G protein-coupled receptor binding#GO:0001664;signaling receptor binding#GO:0005102 regulation of biological process#GO:0050789;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cytoplasm#GO:0005737;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;cytoplasmic side of plasma membrane#GO:0009898;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622;extrinsic component of membrane#GO:0019898 heterotrimeric G-protein#PC00117;G-protein#PC00020 Endothelin signaling pathway#P00019>Gq#P00586;Metabotropic glutamate receptor group I pathway#P00041>G-Protein#P01057;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>Gqalpha#P05927;Gonadotropin-releasing hormone receptor pathway#P06664>gnaq/11#P06841;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>G-Protein#P01073;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Galphaq#P00826;Thyrotropin-releasing hormone receptor signaling pathway#P04394>G-Protein#P04584;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Gqalpha#P00732;Oxytocin receptor mediated signaling pathway#P04391>G-Protein#P04534;Histamine H1 receptor mediated signaling pathway#P04385>G-Protein#P04488;Wnt signaling pathway#P00057>Galpha#P01451;5HT2 type receptor mediated signaling pathway#P04374>G-protein#P04416;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Galphai/q#P00873;Cortocotropin releasing factor receptor signaling pathway#P04380>G-Protein#P04458;PI3 kinase pathway#P00048>Galpha#P01199 CIOIN|Ensembl=ENSCING00000006797.3|UniProtKB=F6VDB6 F6VDB6 PTHR22957:SF168 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC DOMAIN-CONTAINING PROTEIN KINASE-LIKE PROTEIN nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 regulation of molecular function#GO:0065009;regulation of GTPase activity#GO:0043087;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;activation of GTPase activity#GO:0090630;biological regulation#GO:0065007;positive regulation of molecular function#GO:0044093;regulation of hydrolase activity#GO:0051336;regulation of catalytic activity#GO:0050790;positive regulation of hydrolase activity#GO:0051345 GTPase-activating protein#PC00257 CIOIN|Ensembl=ENSCING00000011562.2|UniProtKB=F6SZH9 F6SZH9 PTHR24136:SF15 SOWAH (DROSOPHILA) HOMOLOG ANK_REP_REGION DOMAIN-CONTAINING PROTEIN positive regulation of nitrogen compound metabolic process#GO:0051173;protein ubiquitination#GO:0016567;regulation of protein metabolic process#GO:0051246;protein modification by small protein conjugation or removal#GO:0070647;regulation of catabolic process#GO:0009894;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;regulation of nitrogen compound metabolic process#GO:0051171;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;regulation of protein catabolic process#GO:0042176;positive regulation of macromolecule metabolic process#GO:0010604;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;positive regulation of protein metabolic process#GO:0051247;positive regulation of metabolic process#GO:0009893;regulation of macromolecule metabolic process#GO:0060255;nitrogen compound metabolic process#GO:0006807;biological regulation#GO:0065007;positive regulation of catabolic process#GO:0009896;protein metabolic process#GO:0019538;positive regulation of protein catabolic process#GO:0045732;positive regulation of biological process#GO:0048518;protein modification by small protein conjugation#GO:0032446;regulation of metabolic process#GO:0019222;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 CIOIN|Ensembl=ENSCING00000009858.3|UniProtKB=F6XG50 F6XG50 PTHR11046:SF0 OLIGORIBONUCLEASE, MITOCHONDRIAL OLIGORIBONUCLEASE, MITOCHONDRIAL endoribonuclease#PC00094;RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000009426.3|UniProtKB=F6TLE4 F6TLE4 PTHR11142:SF4 PSEUDOURIDYLATE SYNTHASE PSEUDOURIDYLATE SYNTHASE 1 HOMOLOG isomerase activity#GO:0016853;intramolecular transferase activity#GO:0016866;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA modification#GO:0009451;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;mRNA modification#GO:0016556;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;tRNA modification#GO:0006400;primary metabolic process#GO:0044238;pseudouridine synthesis#GO:0001522;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 lyase#PC00144 CIOIN|Ensembl=ENSCING00000021887.1|UniProtKB=Q1RL87 Q1RL87 Ci-ZF(AN1)-2 PTHR14677:SF37 ARSENITE INDUCUBLE RNA ASSOCIATED PROTEIN AIP-1-RELATED AN1-TYPE ZINC FINGER PROTEIN 1 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000008688.3|UniProtKB=F6V3T4 F6V3T4 PTHR24034:SF148 EGF-LIKE DOMAIN-CONTAINING PROTEIN RE58433P extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 CIOIN|Ensembl=ENSCING00000006748.3|UniProtKB=F6Y0N1 F6Y0N1 PTHR15289:SF3 TASTIN TASTIN CIOIN|Ensembl=ENSCING00000018681.1|UniProtKB=H2XL93 H2XL93 LOC100176484 PTHR13387:SF9 PROTEIN HGH1 HOMOLOG PROTEIN HGH1 HOMOLOG CIOIN|Ensembl=ENSCING00000016614.2|UniProtKB=F6UPX6 F6UPX6 LOC100185885 PTHR10559:SF18 TRANSCOBALAMIN-1/GASTRIC INTRINSIC FACTOR TRANSCOBALAMIN II CIOIN|Ensembl=ENSCING00000012499.2|UniProtKB=F6U5A0 F6U5A0 LOC100181901 PTHR24409:SF295 ZINC FINGER PROTEIN 142 AZ2-RELATED sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 CIOIN|Ensembl=ENSCING00000004591.3|UniProtKB=F6WPV3 F6WPV3 LOC100186012 PTHR24346:SF51 MAP/MICROTUBULE AFFINITY-REGULATING KINASE PAS DOMAIN-CONTAINING SERINE_THREONINE-PROTEIN KINASE transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 negative regulation of cellular metabolic process#GO:0031324;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;macromolecule modification#GO:0043412;protein modification process#GO:0036211;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;phosphorylation#GO:0016310;regulation of macromolecule biosynthetic process#GO:0010556;intracellular signal transduction#GO:0035556;protein metabolic process#GO:0019538;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;negative regulation of biosynthetic process#GO:0009890;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cell communication#GO:0007154;negative regulation of metabolic process#GO:0009892;cellular process#GO:0009987;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000005023.3|UniProtKB=F6TA22 F6TA22 LOC100180929 PTHR22950:SF702 AMINO ACID TRANSPORTER AMINO ACID TRANSPORTER PROTEIN L-amino acid transmembrane transporter activity#GO:0015179;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;amino acid transmembrane transporter activity#GO:0015171;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215;organic acid transmembrane transporter activity#GO:0005342 localization#GO:0051179;organic substance transport#GO:0071702;amino acid transmembrane transport#GO:0003333;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;amino acid transport#GO:0006865;organic anion transport#GO:0015711;organic acid transport#GO:0015849;transport#GO:0006810;nitrogen compound transport#GO:0071705;organic acid transmembrane transport#GO:1903825;carboxylic acid transport#GO:0046942;cellular process#GO:0009987;carboxylic acid transmembrane transport#GO:1905039 cellular anatomical entity#GO:0110165;membrane#GO:0016020 amino acid transporter#PC00046;transporter#PC00227 CIOIN|Ensembl=ENSCING00000002867.3|UniProtKB=F6TML4 F6TML4 LOC100183594 PTHR11274:SF0 RAD25/XP-B DNA REPAIR HELICASE GENERAL TRANSCRIPTION AND DNA REPAIR FACTOR IIH HELICASE SUBUNIT XPB DNA metabolism protein#PC00009;DNA helicase#PC00011 CIOIN|Ensembl=ENSCING00000015811.2|UniProtKB=F6RW32 F6RW32 PTHR46551:SF1 SAP DOMAIN-CONTAINING RIBONUCLEOPROTEIN SAP DOMAIN-CONTAINING RIBONUCLEOPROTEIN poly(A)+ mRNA export from nucleus#GO:0016973;mRNA export from nucleus#GO:0006406;cellular localization#GO:0051641;macromolecule biosynthetic process#GO:0009059;macromolecule localization#GO:0033036;establishment of RNA localization#GO:0051236;macromolecule metabolic process#GO:0043170;transport#GO:0006810;nucleic acid transport#GO:0050657;nitrogen compound transport#GO:0071705;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;mRNA transport#GO:0051028;RNA localization#GO:0006403;localization#GO:0051179;organic substance transport#GO:0071702;nuclear export#GO:0051168;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;RNA transport#GO:0050658;nucleobase-containing compound transport#GO:0015931;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;nuclear transport#GO:0051169;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000014993.2|UniProtKB=F6UV64 F6UV64 PTHR11216:SF174 EH DOMAIN GH06923P localization#GO:0051179;endosomal transport#GO:0016197;cellular localization#GO:0051641;establishment of localization#GO:0051234;transport#GO:0006810;endocytosis#GO:0006897;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;cellular process#GO:0009987;import into cell#GO:0098657 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 membrane traffic protein#PC00150 CIOIN|Ensembl=ENSCING00000010535.3|UniProtKB=F7BBB5 F7BBB5 LOC100180441 PTHR10671:SF108 EPITHELIAL MEMBRANE PROTEIN-RELATED CLAUDIN FAMILY PROTEIN-RELATED cytoskeletal protein#PC00085 CIOIN|Ensembl=ENSCING00000004801.3|UniProtKB=F6REI3 F6REI3 LOC100176459 PTHR14490:SF5 ZINC FINGER, ZZ TYPE PROTEIN KRI1 HOMOLOG cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;RNA processing#GO:0006396;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;ribosome biogenesis#GO:0042254;maturation of 5.8S rRNA#GO:0000460;endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000447;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;maturation of SSU-rRNA#GO:0030490;ribosomal small subunit biogenesis#GO:0042274 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;nuclear lumen#GO:0031981;90S preribosome#GO:0030686 CIOIN|Ensembl=ENSCING00000013021.2|UniProtKB=F6UG73 F6UG73 PTHR19212:SF0 LEUCINE RICH REPEAT IN FLII INTERACTING PROTEIN LD07988P DNA-binding transcription factor#PC00218 CIOIN|Ensembl=ENSCING00000012683.2|UniProtKB=F6U3I5 F6U3I5 LOC778872 PTHR46927:SF3 AGAP005574-PA THAP-TYPE DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000001709.3|UniProtKB=A0A1W2WC94 A0A1W2WC94 LOC100183378 PTHR16231:SF2 COMM DOMAIN-CONTAINING PROTEIN 4-8 FAMILY MEMBER COMM DOMAIN-CONTAINING PROTEIN 7 NF-kappaB binding#GO:0051059;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;protein binding#GO:0005515;transcription factor binding#GO:0008134;binding#GO:0005488;DNA-binding transcription factor binding#GO:0140297 negative regulation of cellular metabolic process#GO:0031324;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;response to cytokine#GO:0034097;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;regulation of RNA biosynthetic process#GO:2001141;negative regulation of NF-kappaB transcription factor activity#GO:0032088;regulation of biological process#GO:0050789;regulation of molecular function#GO:0065009;regulation of biosynthetic process#GO:0009889;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;cytokine-mediated signaling pathway#GO:0019221;negative regulation of DNA-templated transcription#GO:0045892;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;regulation of DNA-binding transcription factor activity#GO:0051090;negative regulation of biosynthetic process#GO:0009890;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;regulation of DNA-templated transcription#GO:0006355;tumor necrosis factor-mediated signaling pathway#GO:0033209;negative regulation of metabolic process#GO:0009892;cell communication#GO:0007154;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;negative regulation of macromolecule biosynthetic process#GO:0010558;response to tumor necrosis factor#GO:0034612;regulation of cellular biosynthetic process#GO:0031326;response to chemical#GO:0042221;cellular response to cytokine stimulus#GO:0071345;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;cellular response to tumor necrosis factor#GO:0071356;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;negative regulation of molecular function#GO:0044092;regulation of cellular metabolic process#GO:0031323;negative regulation of DNA-binding transcription factor activity#GO:0043433 CIOIN|Ensembl=ENSCING00000021290.1|UniProtKB=H2XV92 H2XV92 PTHR24020:SF87 COLLAGEN ALPHA COLLAGEN ALPHA-1(VI) CHAIN-LIKE external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 CIOIN|Ensembl=ENSCING00000013694.2|UniProtKB=F6PS78 F6PS78 PTHR43296:SF2 PEROXISOMAL 2,4-DIENOYL-COA REDUCTASE PEROXISOMAL 2,4-DIENOYL-COA REDUCTASE [(3E)-ENOYL-COA-PRODUCING] oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor#GO:0016628 lipid metabolic process#GO:0006629;oxoacid metabolic process#GO:0043436;fatty acid metabolic process#GO:0006631;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular lipid metabolic process#GO:0044255;organic acid metabolic process#GO:0006082;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;peroxisome#GO:0005777;microbody#GO:0042579;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 reductase#PC00198;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000009651.3|UniProtKB=F6WV94 F6WV94 PTHR14402:SF10 RECEPTOR TRANSPORTING PROTEIN 3CXXC-TYPE DOMAIN-CONTAINING PROTEIN protein binding#GO:0005515;G protein-coupled receptor binding#GO:0001664;binding#GO:0005488;signaling receptor binding#GO:0005102 localization within membrane#GO:0051668;cellular localization#GO:0051641;macromolecule localization#GO:0033036;membrane organization#GO:0061024;protein localization to membrane#GO:0072657;protein targeting#GO:0006605;cellular component organization#GO:0016043;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of protein localization to membrane#GO:0090150;protein targeting to membrane#GO:0006612;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein insertion into membrane#GO:0051205 membrane traffic protein#PC00150 CIOIN|Ensembl=ENSCING00000005808.3|UniProtKB=F6RGX1 F6RGX1 PTHR24068:SF135 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 J2 ubiquitin-like protein conjugating enzyme activity#GO:0061650;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin conjugating enzyme activity#GO:0061631;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 macromolecule modification#GO:0043412;protein catabolic process#GO:0030163;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;post-translational protein modification#GO:0043687;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;protein polyubiquitination#GO:0000209;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;protein ubiquitination#GO:0016567;macromolecule catabolic process#GO:0009057;response to endoplasmic reticulum stress#GO:0034976;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;ERAD pathway#GO:0036503;response to organonitrogen compound#GO:0010243;cellular process#GO:0009987;primary metabolic process#GO:0044238;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;cellular response to stress#GO:0033554 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 Parkinson disease#P00049>Ubc6#P01222 CIOIN|Ensembl=ENSCING00000003574.3|UniProtKB=F6Y8T6 F6Y8T6 PTHR12228:SF0 TRANSCRIPTION INITIATION FACTOR TFIID 55 KD SUBUNIT-RELATED TATA-BOX BINDING PROTEIN ASSOCIATED FACTOR 7 cellular aromatic compound metabolic process#GO:0006725;DNA-templated transcription#GO:0006351;cellular component biogenesis#GO:0044085;protein-DNA complex organization#GO:0071824;RNA metabolic process#GO:0016070;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;protein-DNA complex assembly#GO:0065004;nucleobase-containing compound metabolic process#GO:0006139;RNA polymerase II preinitiation complex assembly#GO:0051123;transcription initiation at RNA polymerase II promoter#GO:0006367;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;DNA-templated transcription initiation#GO:0006352;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular component assembly#GO:0022607;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;protein-containing complex organization#GO:0043933;aromatic compound biosynthetic process#GO:0019438;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;DNA-directed RNA polymerase complex#GO:0000428;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nucleoplasm#GO:0005654;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;transcription factor TFIID complex#GO:0005669;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622;RNA polymerase II, holoenzyme#GO:0016591;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;transcription regulator complex#GO:0005667;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 general transcription factor#PC00259 General transcription regulation#P00023>TBP-associated factors#P00658;Transcription regulation by bZIP transcription factor#P00055>TBP-associated factors#P01385 CIOIN|Ensembl=ENSCING00000004092.4|UniProtKB=F6YHN3 F6YHN3 PTHR16074:SF4 BARDET-BIEDL SYNDROME 7 PROTEIN BARDET-BIEDL SYNDROME 7 PROTEIN cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;cilium assembly#GO:0060271;cell projection organization#GO:0030030;macromolecule localization#GO:0033036;transport#GO:0006810;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031;protein localization#GO:0008104;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;organelle organization#GO:0006996;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031 axoneme#GO:0005930;microtubule organizing center#GO:0005815;cytoplasmic region#GO:0099568;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;ciliary basal body#GO:0036064;ciliary plasm#GO:0097014;plasma membrane bounded cell projection cytoplasm#GO:0032838;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cytoskeleton#GO:0005856;BBSome#GO:0034464;cilium#GO:0005929 CIOIN|Ensembl=ENSCING00000022903.1|UniProtKB=H2XY09 H2XY09 PTHR12504:SF0 MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM22 MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM22 HOMOLOG primary active transporter#PC00068;transporter#PC00227 CIOIN|Ensembl=ENSCING00000012590.2|UniProtKB=F6Y3U3 F6Y3U3 PTHR19957:SF411 SYNTAXIN LD23667P molecular adaptor activity#GO:0060090;protein binding#GO:0005515;SNAP receptor activity#GO:0005484;binding#GO:0005488;SNARE binding#GO:0000149;protein-macromolecule adaptor activity#GO:0030674 vesicle fusion#GO:0006906;cellular localization#GO:0051641;organelle localization#GO:0051640;macromolecule localization#GO:0033036;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;membrane fusion#GO:0061025;establishment of localization#GO:0051234;organelle organization#GO:0006996;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;vesicle organization#GO:0016050;intracellular transport#GO:0046907;organelle fusion#GO:0048284 presynapse#GO:0098793;membrane protein complex#GO:0098796;synapse#GO:0045202;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;synaptic vesicle#GO:0008021;SNARE complex#GO:0031201;cell junction#GO:0030054;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;transport vesicle#GO:0030133;secretory vesicle#GO:0099503 SNARE protein#PC00034;membrane traffic protein#PC00150 Adrenaline and noradrenaline biosynthesis#P00001>SNARE#P00072;Parkinson disease#P00049>Syntaxin#P01215 CIOIN|Ensembl=ENSCING00000015490.2|UniProtKB=F6TVN3 F6TVN3 LOC100175543 PTHR11863:SF228 STEROL DESATURASE C-5 STEROL DESATURASE-LIKE PROTEIN-RELATED oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497 sterol metabolic process#GO:0016125;organic hydroxy compound metabolic process#GO:1901615;steroid metabolic process#GO:0008202;lipid metabolic process#GO:0006629;organic cyclic compound metabolic process#GO:1901360;organic hydroxy compound biosynthetic process#GO:1901617;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;lipid biosynthetic process#GO:0008610;steroid biosynthetic process#GO:0006694;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;sterol biosynthetic process#GO:0016126;metabolic process#GO:0008152 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 oxidase#PC00175;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000003370.3|UniProtKB=F7AQ62 F7AQ62 PTHR10519:SF77 GABA-B RECEPTOR GAMMA-AMINOBUTYRIC ACID TYPE B RECEPTOR SUBUNIT 1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 biological regulation#GO:0065007;regulation of biological process#GO:0050789;cell communication#GO:0007154;cellular process#GO:0009987;cell-cell signaling#GO:0007267;signaling#GO:0023052 receptor complex#GO:0043235;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;plasma membrane signaling receptor complex#GO:0098802;plasma membrane protein complex#GO:0098797;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 GABA-B receptor II signaling#P05731>GABA-B receptor#P05756 CIOIN|Ensembl=ENSCING00000021458.1|UniProtKB=H2XNV1 H2XNV1 PTHR10459:SF108 DNA LIGASE POLY [ADP-RIBOSE] POLYMERASE transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;glycosyltransferase activity#GO:0016757;pentosyltransferase activity#GO:0016763;catalytic activity#GO:0003824 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;double-strand break repair#GO:0006302;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;post-translational protein modification#GO:0043687;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;response to stress#GO:0006950;nitrogen compound metabolic process#GO:0006807;cellular response to stress#GO:0033554;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259;metabolic process#GO:0008152 intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA metabolism protein#PC00009 CIOIN|Ensembl=ENSCING00000002491.3|UniProtKB=F7AK99 F7AK99 PTHR23077:SF171 AAA-FAMILY ATPASE NUCLEAR VALOSIN-CONTAINING PROTEIN-LIKE pyrophosphatase activity#GO:0016462;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;ATP hydrolysis activity#GO:0016887 primary active transporter#PC00068;transporter#PC00227 CIOIN|Ensembl=ENSCING00000023713.1|UniProtKB=H2XVQ5 H2XVQ5 PTHR11929:SF145 ALPHA- 1,3 -FUCOSYLTRANSFERASE ALPHA-(1,3)-FUCOSYLTRANSFERASE FUT-1 transferase activity#GO:0016740;fucosyltransferase activity#GO:0008417;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 glycosylation#GO:0070085;metabolic process#GO:0008152 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000006109.3|UniProtKB=F6YWJ3 F6YWJ3 LOC100181970 PTHR46661:SF4 E3 UBIQUITIN-PROTEIN LIGASE ZNRF1-LIKE PROTEIN RING-TYPE DOMAIN-CONTAINING PROTEIN transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein K48-linked ubiquitination#GO:0070936;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein polyubiquitination#GO:0000209;proteasomal protein catabolic process#GO:0010498;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;membrane#GO:0016020;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000012729.2|UniProtKB=F7A9T3 F7A9T3 LOC100179830 PTHR13345:SF9 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 10 PROTEIN UXT molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;protein-macromolecule adaptor activity#GO:0030674 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of RNA metabolic process#GO:0051254;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;mediator complex#GO:0016592;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031;general transcription factor#PC00259 CIOIN|Ensembl=ENSCING00000018578.1|UniProtKB=H2XM88 H2XM88 LOC104265547 PTHR31879:SF2 DET1- AND DDB1-ASSOCIATED PROTEIN 1 DET1- AND DDB1-ASSOCIATED PROTEIN 1 positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of proteolysis#GO:0030162;regulation of protein metabolic process#GO:0051246;regulation of catabolic process#GO:0009894;positive regulation of proteolysis involved in protein catabolic process#GO:1903052;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of proteasomal protein catabolic process#GO:1901800;regulation of protein catabolic process#GO:0042176;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060;regulation of proteolysis involved in protein catabolic process#GO:1903050;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of proteolysis#GO:0045862;regulation of proteasomal protein catabolic process#GO:0061136;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;positive regulation of protein metabolic process#GO:0051247;positive regulation of metabolic process#GO:0009893;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;positive regulation of catabolic process#GO:0009896;positive regulation of protein catabolic process#GO:0045732;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434;positive regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032436 intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;cullin-RING ubiquitin ligase complex#GO:0031461;catalytic complex#GO:1902494;transferase complex#GO:1990234;Cul4-RING E3 ubiquitin ligase complex#GO:0080008 CIOIN|Ensembl=ENSCING00000021630.1|UniProtKB=H2Y2D1 H2Y2D1 LOC100180817 PTHR10264:SF130 BAND 7 PROTEIN-RELATED STOMATIN-LIKE PROTEIN 1 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cytoskeletal protein#PC00085 CIOIN|Ensembl=ENSCING00000002152.3|UniProtKB=F6SMU1 F6SMU1 ror PTHR45805:SF2 NUCLEAR HORMONE RECEPTOR HR3-RELATED NUCLEAR HORMONE RECEPTOR HR3-RELATED cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;signaling receptor activity#GO:0038023;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular transducer activity#GO:0060089;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C4 zinc finger nuclear receptor#PC00169;zinc finger transcription factor#PC00244 CIOIN|Ensembl=ENSCING00000015053.2|UniProtKB=F6S8F6 F6S8F6 PTHR22812:SF112 CHROMOBOX PROTEIN CHROMATOR, ISOFORM A-RELATED protein binding#GO:0005515;protein-containing complex binding#GO:0044877;methylated histone binding#GO:0035064;histone binding#GO:0042393;binding#GO:0005488;chromatin binding#GO:0003682;modification-dependent protein binding#GO:0140030 negative regulation of gene expression#GO:0010629;negative regulation of cellular metabolic process#GO:0031324;protein-DNA complex organization#GO:0071824;negative regulation of biological process#GO:0048519;negative regulation of biosynthetic process#GO:0009890;heterochromatin formation#GO:0031507;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;negative regulation of gene expression, epigenetic#GO:0045814;cellular process#GO:0009987;epigenetic regulation of gene expression#GO:0040029;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;negative regulation of macromolecule biosynthetic process#GO:0010558;heterochromatin organization#GO:0070828;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;protein-containing complex organization#GO:0043933;regulation of cellular process#GO:0050794;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;chromatin remodeling#GO:0006338;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromatin#GO:0000785;protein-DNA complex#GO:0032993;chromosome#GO:0005694;chromosome, centromeric region#GO:0000775;chromosomal region#GO:0098687;heterochromatin#GO:0000792;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000005562.3|UniProtKB=F6USV3 F6USV3 LOC100176696 PTHR23277:SF108 NECTIN-RELATED FASCICLIN-3 cell-cell adhesion via plasma-membrane adhesion molecules#GO:0098742;heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules#GO:0007157;cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987;homophilic cell adhesion via plasma membrane adhesion molecules#GO:0007156 cell junction#GO:0030054;adherens junction#GO:0005912;cellular anatomical entity#GO:0110165;cell-cell junction#GO:0005911;anchoring junction#GO:0070161 cell adhesion molecule#PC00069 CIOIN|Ensembl=ENSCING00000008699.3|UniProtKB=A0A1W3JV80 A0A1W3JV80 LOC100185373 PTHR46600:SF11 THAP DOMAIN-CONTAINING THAP DOMAIN-CONTAINING PROTEIN 10 zinc finger transcription factor#PC00244 CIOIN|Ensembl=ENSCING00000007759.3|UniProtKB=F6XTV8 F6XTV8 LOC100183293 PTHR11477:SF0 TRANSCRIPTION FACTOR S-II ZINC FINGER DOMAIN-CONTAINING PROTEIN IP08861P-RELATED cellular aromatic compound metabolic process#GO:0006725;DNA-templated transcription#GO:0006351;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;RNA biosynthetic process#GO:0032774;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;aromatic compound biosynthetic process#GO:0019438;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 general transcription factor#PC00259 CIOIN|Ensembl=ENSCING00000010580.3|UniProtKB=F6Z4Q8 F6Z4Q8 PTHR23282:SF101 APICAL ENDOSOMAL GLYCOPROTEIN PRECURSOR. MAM DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000005134.3|UniProtKB=F6VXU3 F6VXU3 fli_erg4 PTHR11849:SF59 ETS ETS DOMAIN-CONTAINING PROTEIN transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 CIOIN|Ensembl=ENSCING00000025200.1|UniProtKB=Q8HIN8 Q8HIN8 ATPase 6 PTHR11410:SF0 ATP SYNTHASE SUBUNIT A ATP SYNTHASE SUBUNIT A monoatomic cation channel activity#GO:0005261;ligase activity#GO:0016874;inorganic molecular entity transmembrane transporter activity#GO:0015318;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;catalytic activity#GO:0003824;proton transmembrane transporter activity#GO:0015078;proton channel activity#GO:0015252;proton-transporting ATP synthase activity, rotational mechanism#GO:0046933;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;inorganic cation transmembrane transporter activity#GO:0022890;channel activity#GO:0015267;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 cellular aromatic compound metabolic process#GO:0006725;ribonucleoside triphosphate metabolic process#GO:0009199;nucleoside triphosphate metabolic process#GO:0009141;carbohydrate derivative metabolic process#GO:1901135;ATP biosynthetic process#GO:0006754;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ATP metabolic process#GO:0046034;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;purine nucleoside triphosphate biosynthetic process#GO:0009145;heterocycle metabolic process#GO:0046483;purine ribonucleoside triphosphate metabolic process#GO:0009205;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;ribonucleoside triphosphate biosynthetic process#GO:0009201;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;proton motive force-driven ATP synthesis#GO:0015986;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;nucleoside triphosphate biosynthetic process#GO:0009142;organophosphate metabolic process#GO:0019637;purine nucleoside triphosphate metabolic process#GO:0009144;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;ATPase complex#GO:1904949;cellular anatomical entity#GO:0110165;membrane#GO:0016020;proton-transporting ATP synthase complex#GO:0045259;proton-transporting two-sector ATPase complex#GO:0016469 ATP synthase#PC00002;primary active transporter#PC00068;transporter#PC00227 ATP synthesis#P02721>ATP synthetase F0#P02797 CIOIN|Ensembl=ENSCING00000000420.3|UniProtKB=H2Y1M2 H2Y1M2 PTHR19134:SF527 RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 7 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;protein tyrosine phosphatase activity#GO:0004725;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 protein phosphatase#PC00195;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000024900.1|UniProtKB=H2XS91 H2XS91 LOC100178149 PTHR47170:SF2 MALONYL-COA ACP TRANSACYLASE, ACP-BINDING MALONYL-COA:ACP TRANSACYLASE (MAT) DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000000668.3|UniProtKB=F6QWW6 F6QWW6 LOC100185905 PTHR11934:SF0 RIBOSE-5-PHOSPHATE ISOMERASE RIBOSE-5-PHOSPHATE ISOMERASE isomerase activity#GO:0016853;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;monosaccharide metabolic process#GO:0005996;heterocycle metabolic process#GO:0046483;carbohydrate derivative metabolic process#GO:1901135;generation of precursor metabolites and energy#GO:0006091;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;pyridine nucleotide metabolic process#GO:0019362;nicotinamide nucleotide metabolic process#GO:0046496;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;glucose 6-phosphate metabolic process#GO:0051156;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;pyridine-containing compound metabolic process#GO:0072524;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;carbohydrate metabolic process#GO:0005975;NADP metabolic process#GO:0006739;purine nucleotide metabolic process#GO:0006163;small molecule metabolic process#GO:0044281;nucleobase-containing small molecule metabolic process#GO:0055086;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 isomerase#PC00135;metabolite interconversion enzyme#PC00262 Pentose phosphate pathway#P02762>Ribulose 5-P Isomerase#P03071 CIOIN|Ensembl=ENSCING00000015738.2|UniProtKB=F6R2P7 F6R2P7 PTHR45686:SF4 ADP-RIBOSYLATION FACTOR GTPASE ACTIVATING PROTEIN 3, ISOFORM H-RELATED ADP-RIBOSYLATION FACTOR GTPASE ACTIVATING PROTEIN 3, ISOFORM H vesicle targeting, to, from or within Golgi#GO:0048199;cellular localization#GO:0051641;organelle localization#GO:0051640;vesicle localization#GO:0051648;membrane organization#GO:0061024;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;vesicle targeting#GO:0006903;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;vesicle budding from membrane#GO:0006900;establishment of vesicle localization#GO:0051650;organelle organization#GO:0006996;vesicle organization#GO:0016050;establishment of localization in cell#GO:0051649;establishment of organelle localization#GO:0051656 GTPase-activating protein#PC00257 CIOIN|Ensembl=ENSCING00000006722.3|UniProtKB=F7A7C3 F7A7C3 PTHR22836:SF0 WD40 REPEAT PROTEIN PRE-MRNA 3' END PROCESSING PROTEIN WDR33 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;RNA processing#GO:0006396;mRNA polyadenylation#GO:0006378;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;mRNA 3'-end processing#GO:0031124;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;mRNA processing#GO:0006397;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;mRNA cleavage factor complex#GO:0005849;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;mRNA cleavage and polyadenylation specificity factor complex#GO:0005847;intracellular anatomical structure#GO:0005622 RNA processing factor#PC00147;RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000003189.3|UniProtKB=F6SQE1 F6SQE1 PTHR12622:SF45 DELTEX-RELATED RING-TYPE E3 UBIQUITIN TRANSFERASE transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein ubiquitination#GO:0016567;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cell communication#GO:0007154;cellular process#GO:0009987;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;nitrogen compound metabolic process#GO:0006807;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;signaling#GO:0023052;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;Notch signaling pathway#GO:0007219 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000009848.3|UniProtKB=F6XGM8 F6XGM8 PTHR21064:SF1 AMINOGLYCOSIDE PHOSPHOTRANSFERASE DOMAIN-CONTAINING PROTEIN-RELATED HYDROXYLYSINE KINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301 CIOIN|Ensembl=ENSCING00000003591.3|UniProtKB=F6XK10 F6XK10 PTHR43740:SF2 LEUCYL-TRNA SYNTHETASE LEUCINE--TRNA LIGASE, MITOCHONDRIAL catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;ligase activity#GO:0016874;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;peptide biosynthetic process#GO:0043043;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 aminoacyl-tRNA synthetase#PC00047;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000003945.3|UniProtKB=F6ZLL3 F6ZLL3 LOC100177796 PTHR43895:SF164 CALCIUM/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE-RELATED CALCIUM_CALMODULIN-DEPENDENT PROTEIN KINASE KINASE transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;nitrogen compound metabolic process#GO:0006807;biological regulation#GO:0065007;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 CIOIN|Ensembl=ENSCING00000005825.3|UniProtKB=F6VVT3 F6VVT3 LOC100179181 PTHR36978:SF4 P-LOOP CONTAINING NUCLEOTIDE TRIPHOSPHATE HYDROLASE P-LOOP CONTAINING NUCLEOSIDE TRIPHOSPHATE HYDROLASE PROTEIN metabolite interconversion enzyme#PC00262;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000008770.3|UniProtKB=F6T010 F6T010 PTHR24291:SF201 CYTOCHROME P450 FAMILY 4 CYTOCHROME P450, FAMILY 4, SUBFAMILY B, POLYPEPTIDE 7 oxygenase#PC00177;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000011356.2|UniProtKB=F6UNA3 F6UNA3 PTHR10926:SF0 CELL CYCLE CONTROL PROTEIN 50 CDC50, ISOFORM A cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000010092.3|UniProtKB=F6PIT2 F6PIT2 PTHR46473:SF23 GH08155P GH08155P CIOIN|Ensembl=ENSCING00000024788.1|UniProtKB=H2XJM7 H2XJM7 PTHR10924:SF4 MAJOR FACILITATOR SUPERFAMILY PROTEIN-RELATED GH15861P tetrapyrrole binding#GO:0046906;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;binding#GO:0005488;organic cyclic compound binding#GO:0097159;heme binding#GO:0020037 localization#GO:0051179;organic substance transport#GO:0071702;metal ion transport#GO:0030001;establishment of localization#GO:0051234;transport#GO:0006810;monoatomic cation transport#GO:0006812;nitrogen compound transport#GO:0071705;iron ion transport#GO:0006826;transition metal ion transport#GO:0000041;monoatomic ion transport#GO:0006811 cellular anatomical entity#GO:0110165;membrane#GO:0016020 secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000001519.3|UniProtKB=F6Z4G6 F6Z4G6 LOC108950147 PTHR11630:SF46 DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER DNA REPLICATION LICENSING FACTOR MCM3-RELATED ATP-dependent activity, acting on DNA#GO:0008094;nucleic acid binding#GO:0003676;helicase activity#GO:0004386;ATP-dependent activity#GO:0140657;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;single-stranded DNA binding#GO:0003697;DNA binding#GO:0003677;catalytic activity, acting on a nucleic acid#GO:0140640;DNA helicase activity#GO:0003678;catalytic activity, acting on DNA#GO:0140097;single-stranded DNA helicase activity#GO:0017116 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;double-strand break repair#GO:0006302;cell cycle process#GO:0022402;nucleobase-containing compound metabolic process#GO:0006139;mitotic cell cycle process#GO:1903047;DNA damage response#GO:0006974;mitotic cell cycle#GO:0000278;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;recombinational repair#GO:0000725;DNA-templated DNA replication#GO:0006261;cell cycle DNA replication#GO:0044786;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;nuclear DNA replication#GO:0033260;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;double-strand break repair via homologous recombination#GO:0000724;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;mitotic DNA replication initiation#GO:1902975;response to stress#GO:0006950;double-strand break repair via break-induced replication#GO:0000727;mitotic DNA replication#GO:1902969;cell cycle#GO:0007049;cellular response to stress#GO:0033554;DNA replication#GO:0006260;DNA replication initiation#GO:0006270;DNA strand elongation involved in DNA replication#GO:0006271;DNA metabolic process#GO:0006259 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;MCM complex#GO:0042555;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA metabolism protein#PC00009 CIOIN|Ensembl=ENSCING00000011883.2|UniProtKB=F6YJE0 F6YJE0 PTHR44499:SF1 JOUBERIN JOUBERIN organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cell projection organization#GO:0030030;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection assembly#GO:0120031;motile cilium assembly#GO:0044458;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;microtubule cytoskeleton#GO:0015630;ciliary basal body#GO:0036064;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cilium#GO:0005929;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000001829.3|UniProtKB=F6WII1 F6WII1 LOC100179515 PTHR12694:SF8 TRANSCRIPTION INITIATION FACTOR IIA SUBUNIT 1 TRANSCRIPTION INITIATION FACTOR IIA SUBUNIT 1 cellular aromatic compound metabolic process#GO:0006725;DNA-templated transcription#GO:0006351;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;gene expression#GO:0010467;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;aromatic compound biosynthetic process#GO:0019438;transcription by RNA polymerase II#GO:0006366;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 RNA metabolism protein#PC00031;general transcription factor#PC00259 General transcription regulation#P00023>TFIIA complex#P00662;Transcription regulation by bZIP transcription factor#P00055>TFIIA complex#P01390 CIOIN|Ensembl=ENSCING00000005626.3|UniProtKB=F7ASM9 F7ASM9 LOC100180757 PTHR23055:SF172 CALCIUM BINDING PROTEINS EF-HAND DOMAIN-CONTAINING PROTEIN cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488 calmodulin-related#PC00061 CIOIN|Ensembl=ENSCING00000006783.3|UniProtKB=H2XV03 H2XV03 PTHR19134:SF540 RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE TYROSINE-PROTEIN PHOSPHATASE 99A hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;protein tyrosine phosphatase activity#GO:0004725;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 protein phosphatase#PC00195;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000005489.3|UniProtKB=F6X923 F6X923 PTHR11731:SF202 PROTEASE FAMILY S9B,C DIPEPTIDYL-PEPTIDASE IV-RELATED DIPEPTIDYL PEPTIDASE FAMILY MEMBER 2 hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 serine protease#PC00203;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000001357.3|UniProtKB=F7ABR6 F7ABR6 LOC100186673 PTHR10909:SF250 ELECTRON TRANSPORT OXIDOREDUCTASE PEROXISOMAL ACYL-COENZYME A OXIDASE 1 nucleotide binding#GO:0000166;fatty acid binding#GO:0005504;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;organic cyclic compound binding#GO:0097159;carboxylic acid binding#GO:0031406;nucleoside phosphate binding#GO:1901265;flavin adenine dinucleotide binding#GO:0050660;heterocyclic compound binding#GO:1901363;lipid binding#GO:0008289;anion binding#GO:0043168;ion binding#GO:0043167;organic acid binding#GO:0043177 oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;lipid oxidation#GO:0034440;cellular metabolic process#GO:0044237;homeostatic process#GO:0042592;lipid catabolic process#GO:0016042;lipid modification#GO:0030258;chemical homeostasis#GO:0048878;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;fatty acid catabolic process#GO:0009062;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;fatty acid metabolic process#GO:0006631;small molecule catabolic process#GO:0044282;fatty acid beta-oxidation#GO:0006635;lipid homeostasis#GO:0055088;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;cellular lipid metabolic process#GO:0044255;cellular lipid catabolic process#GO:0044242;carboxylic acid metabolic process#GO:0019752;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;monocarboxylic acid catabolic process#GO:0072329 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;microbody#GO:0042579;membrane-bounded organelle#GO:0043227;peroxisome#GO:0005777;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000004953.3|UniProtKB=F7A6L8 F7A6L8 LOC100181768 PTHR14938:SF2 HCLS1-ASSOCIATED PROTEIN X-1 HCLS1-ASSOCIATED PROTEIN X-1 regulation of anatomical structure size#GO:0090066;negative regulation of biological process#GO:0048519;regulation of apoptotic process#GO:0042981;regulation of actin filament length#GO:0030832;regulation of organelle organization#GO:0033043;regulation of actin filament organization#GO:0110053;regulation of cellular component organization#GO:0051128;cellular component organization#GO:0016043;regulation of actin polymerization or depolymerization#GO:0008064;cellular process#GO:0009987;negative regulation of apoptotic process#GO:0043066;regulation of actin filament polymerization#GO:0030833;regulation of cellular component size#GO:0032535;regulation of supramolecular fiber organization#GO:1902903;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of cytoskeleton organization#GO:0051493;regulation of protein-containing complex assembly#GO:0043254;regulation of biological quality#GO:0065008;regulation of cellular process#GO:0050794;negative regulation of programmed cell death#GO:0043069;regulation of cellular component biogenesis#GO:0044087;biological regulation#GO:0065007;regulation of actin cytoskeleton organization#GO:0032956;regulation of actin filament-based process#GO:0032970;regulation of protein polymerization#GO:0032271;negative regulation of cellular process#GO:0048523;regulation of programmed cell death#GO:0043067 sarcoplasmic reticulum#GO:0016529;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;coated vesicle#GO:0030135;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;apical part of cell#GO:0045177;intracellular anatomical structure#GO:0005622;apical plasma membrane#GO:0016324;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;clathrin-coated vesicle#GO:0030136;actin cytoskeleton#GO:0015629;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;plasma membrane region#GO:0098590;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;endoplasmic reticulum#GO:0005783;plasma membrane#GO:0005886 CIOIN|Ensembl=ENSCING00000021790.1|UniProtKB=H2Y040 H2Y040 LOC100184752 PTHR11711:SF30 ADP RIBOSYLATION FACTOR-RELATED ADP-RIBOSYLATION FACTOR 1 carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;anion binding#GO:0043168 cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 G-protein#PC00020 Integrin signalling pathway#P00034>Arf1#P00923;Huntington disease#P00029>ARF#P00786 CIOIN|Ensembl=ENSCING00000003287.3|UniProtKB=F6WN20 F6WN20 LOC100179647 PTHR28618:SF1 CENTROSOMAL PROTEIN POC5 CENTROSOMAL PROTEIN POC5 CIOIN|Ensembl=ENSCING00000008357.3|UniProtKB=F7AK31 F7AK31 LOC100179311 PTHR23122:SF69 MEMBRANE-ASSOCIATED GUANYLATE KINASE MAGUK FI17352P1 cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000011252.2|UniProtKB=F7AF81 F7AF81 PTHR21286:SF0 NUCLEAR PORE COMPLEX PROTEIN NUP160 NUCLEAR PORE COMPLEX PROTEIN NUP160 structural molecule activity#GO:0005198;structural constituent of nuclear pore#GO:0017056 envelope#GO:0031975;nuclear pore#GO:0005643;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear envelope#GO:0005635;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622 transporter#PC00227 CIOIN|Ensembl=ENSCING00000006207.3|UniProtKB=F6ZE87 F6ZE87 PTHR23356:SF16 DPY30-RELATED DPY30 DOMAIN CONTAINING 2 membrane-enclosed lumen#GO:0031974;histone methyltransferase complex#GO:0035097;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;methyltransferase complex#GO:0034708;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;Set1C/COMPASS complex#GO:0048188;nuclear protein-containing complex#GO:0140513 CIOIN|Ensembl=ENSCING00000024396.1|UniProtKB=F6T4X9 F6T4X9 PTHR19143:SF458 FIBRINOGEN/TENASCIN/ANGIOPOEITIN FIBRINOGEN C-TERMINAL DOMAIN-CONTAINING PROTEIN-RELATED external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 CIOIN|Ensembl=ENSCING00000023253.1|UniProtKB=H2XVM2 H2XVM2 LOC100180378 PTHR20583:SF1 TRIPLE QXXK/R MOTIF-CONTAINING PROTEIN TRIPLE QXXK_R MOTIF-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000019637.1|UniProtKB=H2XU60 H2XU60 selk PTHR16875:SF0 SELENOPROTEIN K SELENOPROTEIN K inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;metal ion transport#GO:0030001;transport#GO:0006810;homeostatic process#GO:0042592;monoatomic cation homeostasis#GO:0055080;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;calcium ion transport#GO:0006816;monoatomic ion homeostasis#GO:0050801;localization#GO:0051179;establishment of localization#GO:0051234;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation transport#GO:0006812;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion transport#GO:0006811 intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 CIOIN|Ensembl=ENSCING00000016237.2|UniProtKB=F6ZT75 F6ZT75 LOC100179758 PTHR11929:SF145 ALPHA- 1,3 -FUCOSYLTRANSFERASE ALPHA-(1,3)-FUCOSYLTRANSFERASE FUT-1 transferase activity#GO:0016740;fucosyltransferase activity#GO:0008417;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 glycosylation#GO:0070085;metabolic process#GO:0008152 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000004166.3|UniProtKB=F7BQ44 F7BQ44 PTHR12357:SF89 YTH YT521-B HOMOLOGY DOMAIN-CONTAINING YTH DOMAIN-CONTAINING FAMILY PROTEIN nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of mRNA stability#GO:0043488;regulation of catabolic process#GO:0009894;regulation of mRNA catabolic process#GO:0061013;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of cellular catabolic process#GO:0031331;RNA destabilization#GO:0050779;regulation of biological process#GO:0050789;positive regulation of metabolic process#GO:0009893;regulation of biological quality#GO:0065008;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;positive regulation of mRNA metabolic process#GO:1903313;regulation of RNA stability#GO:0043487;regulation of cellular catabolic process#GO:0031329;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;positive regulation of mRNA catabolic process#GO:0061014;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;post-transcriptional regulation of gene expression#GO:0010608;biological regulation#GO:0065007;positive regulation of catabolic process#GO:0009896;positive regulation of RNA metabolic process#GO:0051254;mRNA destabilization#GO:0061157;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;regulation of mRNA metabolic process#GO:1903311 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000005250.3|UniProtKB=F6V9A1 F6V9A1 LOC100185869 PTHR10744:SF9 40S RIBOSOMAL PROTEIN S11 FAMILY MEMBER 40S RIBOSOMAL PROTEIN S11-RELATED structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic small ribosomal subunit#GO:0022627;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;small ribosomal subunit#GO:0015935;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000011886.2|UniProtKB=F6WK64 F6WK64 PTHR24064:SF577 SOLUTE CARRIER FAMILY 22 MEMBER GH09241P secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000018455.1|UniProtKB=H2XWB7 H2XWB7 LOC100179548 PTHR31548:SF1 CLARIN LD47387P CIOIN|Ensembl=ENSCING00000001738.3|UniProtKB=F7AMR5 F7AMR5 LOC100181712 PTHR11502:SF6 40S RIBOSOMAL PROTEIN S6 SMALL RIBOSOMAL SUBUNIT PROTEIN ES6 ribosomal protein#PC00202;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000009381.3|UniProtKB=F6WBI7 F6WBI7 LOC100180018 PTHR43353:SF5 SUCCINATE-SEMIALDEHYDE DEHYDROGENASE, MITOCHONDRIAL SUCCINATE-SEMIALDEHYDE DEHYDROGENASE, MITOCHONDRIAL nitrogen compound metabolic process#GO:0006807;metabolic process#GO:0008152 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 5-Hydroxytryptamine degredation#P04372>Aldehyde Dehydrogenase#P04402;Aminobutyrate degradation#P02726>Succinate semi-aldehyde dehydrogenase#P02824;Gamma-aminobutyric acid synthesis#P04384>Succinic semialdehyde dehydrogenase#P04481 CIOIN|Ensembl=ENSCING00000022814.1|UniProtKB=H2XKL8 H2XKL8 PTHR10751:SF29 GUANYLATE BINDING PROTEIN ATLASTIN GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;ion binding#GO:0043167;anion binding#GO:0043168 heterotrimeric G-protein#PC00117;G-protein#PC00020 CIOIN|Ensembl=ENSCING00000000010.3|UniProtKB=Q1RL20 Q1RL20 Ci-ZicL-2 PTHR19818:SF139 ZINC FINGER PROTEIN ZIC AND GLI PAIR-RULE PROTEIN ODD-PAIRED sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 CIOIN|Ensembl=ENSCING00000002067.3|UniProtKB=F7AAM4 F7AAM4 PTHR13847:SF200 SARCOSINE DEHYDROGENASE-RELATED SARCOSINE DEHYDROGENASE, MITOCHONDRIAL oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 oxoacid metabolic process#GO:0043436;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;amino acid catabolic process#GO:0009063;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;nitrogen compound metabolic process#GO:0006807;cellular modified amino acid metabolic process#GO:0006575;alpha-amino acid metabolic process#GO:1901605;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;carboxylic acid metabolic process#GO:0019752;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 dehydrogenase#PC00092;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000013009.2|UniProtKB=F6V610 F6V610 PTHR23282:SF146 APICAL ENDOSOMAL GLYCOPROTEIN PRECURSOR. RT07201P-RELATED CIOIN|Ensembl=ENSCING00000003588.3|UniProtKB=Q8T885 Q8T885 Ci-CGRP-RCP PTHR15561:SF0 CALCITONIN GENE-RELATED PEPTIDE-RECEPTOR COMPONENT PROTEIN DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC9 cellular aromatic compound metabolic process#GO:0006725;DNA-templated transcription#GO:0006351;heterocycle metabolic process#GO:0046483;transcription by RNA polymerase III#GO:0006383;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;RNA biosynthetic process#GO:0032774;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;DNA-templated transcription initiation#GO:0006352;aromatic compound biosynthetic process#GO:0019438;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;DNA-directed RNA polymerase complex#GO:0000428;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;RNA polymerase III complex#GO:0005666;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 G-protein coupled receptor#PC00021 CIOIN|Ensembl=ENSCING00000018905.1|UniProtKB=H2XZV1 H2XZV1 PTHR18901:SF38 2-DEOXYGLUCOSE-6-PHOSPHATE PHOSPHATASE 2 PSEUDOURIDINE-5'-PHOSPHATASE hydrolase#PC00121;phosphatase#PC00181 CIOIN|Ensembl=ENSCING00000003113.3|UniProtKB=F6TK98 F6TK98 LOC100177726 PTHR40237:SF1 LD44813P LD44813P CIOIN|Ensembl=ENSCING00000024838.1|UniProtKB=H2XSM5 H2XSM5 PTHR15382:SF8 CTG4A-RELATED CANOPY B CIOIN|Ensembl=ENSCING00000005324.3|UniProtKB=F7BPC2 F7BPC2 PTHR14817:SF2 COILED-COIL DOMAIN-CONTAINING PROTEIN 15 COILED-COIL DOMAIN-CONTAINING PROTEIN 15 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;centrosome#GO:0005813 CIOIN|Ensembl=ENSCING00000001174.3|UniProtKB=F6WAT8 F6WAT8 PTHR12984:SF6 SCY1-RELATED S/T PROTEIN KINASE-LIKE SCY1-LIKE PROTEIN 2 non-receptor serine/threonine protein kinase#PC00167 CIOIN|Ensembl=ENSCING00000003453.3|UniProtKB=F6WXQ7 F6WXQ7 PTHR24299:SF21 CYTOCHROME P450 FAMILY 1 OS09G0441600 PROTEIN oxygenase#PC00177;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000002697.3|UniProtKB=F6X134 F6X134 PTHR10288:SF340 KH DOMAIN CONTAINING RNA BINDING PROTEIN HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN K nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000008282.3|UniProtKB=F6QH95 F6QH95 PTHR10926:SF0 CELL CYCLE CONTROL PROTEIN 50 CDC50, ISOFORM A cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000018372.1|UniProtKB=F6W7L1 F6W7L1 PTHR11119:SF3 XANTHINE-URACIL / VITAMIN C PERMEASE FAMILY MEMBER LD30822P transporter#PC00227 CIOIN|Ensembl=ENSCING00000003645.3|UniProtKB=A0A1W2WLM4 A0A1W2WLM4 LOC100183857 PTHR11552:SF147 GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE CHOLINE DEHYDROGENASE, MITOCHONDRIAL oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000006973.3|UniProtKB=F6SZ37 F6SZ37 PTHR12811:SF0 VACUOLAR PROTEIN SORTING VPS16 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 16 HOMOLOG cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;actin binding#GO:0003779;binding#GO:0005488 localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;endosomal transport#GO:0016197;cellular localization#GO:0051641;vacuole organization#GO:0007033;establishment of localization#GO:0051234;organelle organization#GO:0006996;vacuole fusion, non-autophagic#GO:0042144;transport#GO:0006810;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;cellular component organization#GO:0016043;cellular process#GO:0009987;organelle fusion#GO:0048284 bounding membrane of organelle#GO:0098588;lytic vacuole membrane#GO:0098852;membrane protein complex#GO:0098796;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle tethering complex#GO:0099023;vacuolar membrane#GO:0005774;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;lytic vacuole#GO:0000323;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;lysosomal membrane#GO:0005765;protein-containing complex#GO:0032991;lysosome#GO:0005764;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227 membrane traffic protein#PC00150 CIOIN|Ensembl=ENSCING00000004261.3|UniProtKB=F6V6S8 F6V6S8 LOC100182293 PTHR11404:SF6 SUPEROXIDE DISMUTASE 2 SUPEROXIDE DISMUTASE [MN], MITOCHONDRIAL metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000011423.2|UniProtKB=F7AWP0 F7AWP0 PTHR11482:SF6 ARGININE/DIAMINOPIMELATE/ORNITHINE DECARBOXYLASE ORNITHINE DECARBOXYLASE 1-RELATED lyase activity#GO:0016829;carboxy-lyase activity#GO:0016831;carbon-carbon lyase activity#GO:0016830;catalytic activity#GO:0003824 amine metabolic process#GO:0009308;oxoacid metabolic process#GO:0043436;biogenic amine metabolic process#GO:0006576;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;polyamine metabolic process#GO:0006595;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;alpha-amino acid metabolic process#GO:1901605;polyamine biosynthetic process#GO:0006596;carboxylic acid metabolic process#GO:0019752;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 decarboxylase#PC00089 Ornithine degradation#P02758>Ornithine decarboxylase#P03053 CIOIN|Ensembl=ENSCING00000013962.2|UniProtKB=F6PUC9 F6PUC9 LOC100183772 PTHR43115:SF4 DEHYDROGENASE/REDUCTASE SDR FAMILY MEMBER 11 DEHYDROGENASE_REDUCTASE SDR FAMILY MEMBER 11 oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000006494.3|UniProtKB=F7AB27 F7AB27 LOC100175191 PTHR31017:SF2 LATE SECRETORY PATHWAY PROTEIN AVL9-RELATED DENN DOMAIN-CONTAINING PROTEIN 11 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000007713.3|UniProtKB=F6Z479 F6Z479 PTHR24637:SF377 COLLAGEN COLLAGEN TYPE IX ALPHA 1 CHAIN CIOIN|Ensembl=ENSCING00000021731.1|UniProtKB=H2Y0C6 H2Y0C6 LOC104265311 PTHR31195:SF2 GEO02494P1 GEO02494P1 CIOIN|Ensembl=ENSCING00000008778.3|UniProtKB=F6Y516 F6Y516 PTHR47385:SF18 CALPONIN CALPONIN cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000006217.3|UniProtKB=F6YVU0 F6YVU0 PTHR11377:SF5 N-MYRISTOYL TRANSFERASE GLYCYLPEPTIDE N-TETRADECANOYLTRANSFERASE transferase activity#GO:0016740;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity#GO:0003824;N-acyltransferase activity#GO:0016410 macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular biosynthetic process#GO:0044249;protein acylation#GO:0043543;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;lipoprotein biosynthetic process#GO:0042158;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;lipoprotein metabolic process#GO:0042157;protein metabolic process#GO:0019538;protein lipidation#GO:0006497;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000013426.2|UniProtKB=F6V386 F6V386 PTHR12137:SF33 CARBOHYDRATE SULFOTRANSFERASE CARBOHYDRATE SULFOTRANSFERASE 14 sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824 transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000002131.3|UniProtKB=F6ZV87 F6ZV87 LOC100182749 PTHR24020:SF87 COLLAGEN ALPHA COLLAGEN ALPHA-1(VI) CHAIN-LIKE external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 CIOIN|Ensembl=ENSCING00000007500.3|UniProtKB=F6X7X8 F6X7X8 PTHR23115:SF36 TRANSLATION FACTOR G1 TO S PHASE TRANSITION 2 GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;nucleic acid binding#GO:0003676;translation regulator activity#GO:0045182;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;translation regulator activity, nucleic acid binding#GO:0090079;translation factor activity, RNA binding#GO:0008135 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622 translation factor#PC00223;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000019998.1|UniProtKB=H2XKN2 H2XKN2 LOC100175857 PTHR45624:SF61 MITOCHONDRIAL BASIC AMINO ACIDS TRANSPORTER-RELATED MITOCHONDRIAL BASIC AMINO ACIDS TRANSPORTER transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;organic acid transmembrane transporter activity#GO:0005342;basic amino acid transmembrane transporter activity#GO:0015174;L-amino acid transmembrane transporter activity#GO:0015179;organic anion transmembrane transporter activity#GO:0008514;amino acid transmembrane transporter activity#GO:0015171;transporter activity#GO:0005215 L-amino acid transport#GO:0015807;transmembrane transport#GO:0055085;organic anion transport#GO:0015711;amino acid transport#GO:0006865;organic acid transport#GO:0015849;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942;cellular process#GO:0009987;carboxylic acid transmembrane transport#GO:1905039;localization#GO:0051179;mitochondrial transport#GO:0006839;organic substance transport#GO:0071702;amino acid transmembrane transport#GO:0003333;establishment of localization#GO:0051234;L-alpha-amino acid transmembrane transport#GO:1902475;organic acid transmembrane transport#GO:1903825;mitochondrial transmembrane transport#GO:1990542 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transporter#PC00227 CIOIN|Ensembl=ENSCING00000011555.2|UniProtKB=F6TBU9 F6TBU9 PTHR13132:SF29 ALPHA- 1,6 -FUCOSYLTRANSFERASE ALPHA-(1,6)-FUCOSYLTRANSFERASE transferase activity#GO:0016740;fucosyltransferase activity#GO:0008417;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein glycosylation#GO:0006486;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein N-linked glycosylation#GO:0006487;protein metabolic process#GO:0019538;glycosylation#GO:0070085;glycoprotein metabolic process#GO:0009100;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 glycosyltransferase#PC00111 Notch signaling pathway#P00045>Neurotic#P01115 CIOIN|Ensembl=ENSCING00000009078.3|UniProtKB=F6QES8 F6QES8 LOC100180594 PTHR21277:SF5 TRANSCRIPTIONAL ADAPTER 1 TRANSCRIPTIONAL ADAPTER 1 transcription coactivator activity#GO:0003713;molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;protein-macromolecule adaptor activity#GO:0030674 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 SAGA-type complex#GO:0070461;peptidase complex#GO:1905368;histone acetyltransferase complex#GO:0000123;acetyltransferase complex#GO:1902493;chromatin#GO:0000785;protein-DNA complex#GO:0032993;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein acetyltransferase complex#GO:0031248;protein-containing complex#GO:0032991;chromosome#GO:0005694;SAGA complex#GO:0000124 CIOIN|Ensembl=ENSCING00000011744.1|UniProtKB=F6TAU3 F6TAU3 PTHR31964:SF113 ADENINE NUCLEOTIDE ALPHA HYDROLASES-LIKE SUPERFAMILY PROTEIN USPA DOMAIN-CONTAINING PROTEIN metabolite interconversion enzyme#PC00262;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000017130.2|UniProtKB=F6PKM8 F6PKM8 PTHR24254:SF6 PROTHROMBIN CUBILIN serine protease#PC00203;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000009134.3|UniProtKB=F6S2T0 F6S2T0 PTHR24221:SF636 ATP-BINDING CASSETTE SUB-FAMILY B BILE SALT EXPORT PUMP transmembrane transporter activity#GO:0022857;primary active transmembrane transporter activity#GO:0015399;ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 localization#GO:0051179;cellular process#GO:0009987;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810 plasma membrane region#GO:0098590;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;apical part of cell#GO:0045177;plasma membrane#GO:0005886;apical plasma membrane#GO:0016324 ATP-binding cassette (ABC) transporter#PC00003;transporter#PC00227 CIOIN|Ensembl=ENSCING00000004082.3|UniProtKB=F6Z156 F6Z156 PTHR24073:SF1125 DRAB5-RELATED RE48347P GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;macroautophagy#GO:0016236;macromolecule localization#GO:0033036;transport#GO:0006810;nitrogen compound transport#GO:0071705;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;organelle assembly#GO:0070925;process utilizing autophagic mechanism#GO:0061919;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;vacuole organization#GO:0007033;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;organelle organization#GO:0006996;protein transport#GO:0015031;autophagosome assembly#GO:0000045;catabolic process#GO:0009056;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;autophagy#GO:0006914;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 cellular anatomical entity#GO:0110165;endomembrane system#GO:0012505 small GTPase#PC00208;G-protein#PC00020 CIOIN|Ensembl=ENSCING00000013383.2|UniProtKB=F6VSJ3 F6VSJ3 LOC778708 PTHR13935:SF106 ACHAETE-SCUTE TRANSCRIPTION FACTOR-RELATED ACHAETE-SCUTE COMPLEX PROTEIN T5-RELATED sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;basic helix-loop-helix transcription factor#PC00055 CIOIN|Ensembl=ENSCING00000008995.2|UniProtKB=F6PKC1 F6PKC1 LOC100178123 PTHR20883:SF14 PHYTANOYL-COA DIOXYGENASE DOMAIN CONTAINING 1 PHYTANOYL-COA DIOXYGENASE oxygenase#PC00177;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000006067.3|UniProtKB=F6ZG18 F6ZG18 PTHR23281:SF39 MERLIN/MOESIN/EZRIN/RADIXIN MOESIN_EZRIN_RADIXIN HOMOLOG 2 cytoskeletal protein binding#GO:0008092;integrin binding#GO:0005178;binding#GO:0005488;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;signaling receptor binding#GO:0005102;actin binding#GO:0003779 regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;regulation of cell population proliferation#GO:0042127;regulation of anatomical structure morphogenesis#GO:0022603;regulation of organelle organization#GO:0033043;regulation of signaling#GO:0023051;positive regulation of transport#GO:0051050;regulation of localization#GO:0032879;regulation of cellular component organization#GO:0051128;regulation of cellular localization#GO:0060341;regulation of intracellular signal transduction#GO:1902531;regulation of vesicle-mediated transport#GO:0060627;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of transport#GO:0051049;regulation of cell shape#GO:0008360;regulation of biological quality#GO:0065008;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of cellular component biogenesis#GO:0044087;regulation of signal transduction#GO:0009966;regulation of organelle assembly#GO:1902115;biological regulation#GO:0065007;negative regulation of cell population proliferation#GO:0008285;positive regulation of protein localization#GO:1903829;positive regulation of biological process#GO:0048518;negative regulation of cellular process#GO:0048523;regulation of protein localization#GO:0032880 filopodium#GO:0030175;anchoring junction#GO:0070161;cell-cell junction#GO:0005911;cell junction#GO:0030054;actin-based cell projection#GO:0098858;adherens junction#GO:0005912;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;plasma membrane#GO:0005886;apical part of cell#GO:0045177 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 CIOIN|Ensembl=ENSCING00000022359.1|UniProtKB=H2XK16 H2XK16 LOC100186757 PTHR11426:SF280 HISTONE H3 HISTONE H3.3 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 DNA replication#P00017>Histones#P00527 CIOIN|Ensembl=ENSCING00000018889.1|UniProtKB=H2XVM3 H2XVM3 PTHR15704:SF7 SUPERKILLER 3 PROTEIN-RELATED SUPERKILLER COMPLEX PROTEIN 3 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;heterocycle catabolic process#GO:0046700;RNA metabolic process#GO:0016070;nucleobase-containing compound metabolic process#GO:0006139;cellular nitrogen compound catabolic process#GO:0044270;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;mRNA catabolic process#GO:0006402;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;organic substance catabolic process#GO:1901575;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;negative regulation of biosynthetic process#GO:0009890;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;nuclear-transcribed mRNA catabolic process#GO:0000956;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;nucleobase-containing compound catabolic process#GO:0034655;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000003328.3|UniProtKB=F6SFI7 F6SFI7 PTHR22624:SF52 CYSTEINE PROTEASE ATG4 CYSTEINE PROTEASE cysteine-type peptidase activity#GO:0008234;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197 microautophagy#GO:0016237;cellular component biogenesis#GO:0044085;macroautophagy#GO:0016236;macromolecule modification#GO:0043412;mitophagy#GO:0000423;protein modification process#GO:0036211;gene expression#GO:0010467;autophagy of mitochondrion#GO:0000422;biosynthetic process#GO:0009058;post-translational protein modification#GO:0043687;protein processing#GO:0016485;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;cellular component disassembly#GO:0022411;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;mitochondrion organization#GO:0007005;protein metabolic process#GO:0019538;protein lipidation#GO:0006497;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular component assembly#GO:0022607;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular component organization#GO:0016043;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organelle disassembly#GO:1903008;lipoprotein biosynthetic process#GO:0042158;primary metabolic process#GO:0044238;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;autophagosome assembly#GO:0000045;lipoprotein metabolic process#GO:0042157;autophagy#GO:0006914;piecemeal microautophagy of the nucleus#GO:0034727 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 cysteine protease#PC00081;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000017391.2|UniProtKB=Q1RQ09 Q1RQ09 Ci-ZF(C2H2)-53 PTHR24399:SF23 ZINC FINGER AND BTB DOMAIN-CONTAINING C2H2-TYPE DOMAIN-CONTAINING PROTEIN cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription repressor activity#GO:0001217;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 CIOIN|Ensembl=ENSCING00000023386.1|UniProtKB=H2XSG8 H2XSG8 PTHR11909:SF300 CASEIN KINASE-RELATED TAU-TUBULIN KINASE HOMOLOG ASATOR transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular process#GO:0009987;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 Wnt signaling pathway#P00057>Casein Kinase 1#P01460;Parkinson disease#P00049>Casein kinase I#P01242 CIOIN|Ensembl=ENSCING00000024189.1|UniProtKB=H2XYX4 H2XYX4 PTHR24125:SF5 ANKYRIN REPEAT AND DEATH DOMAIN-CONTAINING PROTEIN ANKYRIN REPEAT PROTEIN CIOIN|Ensembl=ENSCING00000019338.1|UniProtKB=H2Y3T2 H2Y3T2 PTHR38681:SF1 RETROVIRUS-RELATED POL POLYPROTEIN FROM TRANSPOSON 412-LIKE PROTEIN-RELATED RETROVIRUS-RELATED POL POLYPROTEIN FROM TRANSPOSON 412-LIKE PROTEIN CIOIN|Ensembl=ENSCING00000014128.2|UniProtKB=F6SQW0 F6SQW0 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE SSU-1 sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824 cellular metabolic process#GO:0044237;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000001526.3|UniProtKB=F6ZGD4 F6ZGD4 LOC100185122 PTHR23323:SF26 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 18 HOMOLOG molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 organelle localization#GO:0051640;transport#GO:0006810;endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;exocytic process#GO:0140029;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;endosome organization#GO:0007032;vacuole organization#GO:0007033;exocytosis#GO:0006887;establishment of localization#GO:0051234;secretion#GO:0046903;organelle organization#GO:0006996;vesicle organization#GO:0016050;export from cell#GO:0140352;organelle fusion#GO:0048284;secretion by cell#GO:0032940 membrane protein complex#GO:0098796;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle tethering complex#GO:0099023;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227 membrane trafficking regulatory protein#PC00151 CIOIN|Ensembl=ENSCING00000016010.2|UniProtKB=F6VVE9 F6VVE9 PTHR24173:SF78 ANKYRIN REPEAT CONTAINING PROTEIN FEM-1 HOMOLOG B scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000003817.3|UniProtKB=F6ZT56 F6ZT56 PTHR15453:SF8 TUMOR SUPPRESSOR CANDIDATE 2 TUMOR SUPPRESSOR CANDIDATE 2 biological regulation#GO:0065007;regulation of biological quality#GO:0065008;regulation of membrane potential#GO:0042391 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000003634.3|UniProtKB=Q4H3G2 Q4H3G2 Ci-FXR PTHR24083:SF98 NUCLEAR HORMONE RECEPTOR NUCLEAR RECEPTOR SUBFAMILY 2 GROUP E MEMBER 1 cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;signaling receptor activity#GO:0038023;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular transducer activity#GO:0060089;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C4 zinc finger nuclear receptor#PC00169;zinc finger transcription factor#PC00244 CIOIN|Ensembl=ENSCING00000022144.1|UniProtKB=H2Y1P4 H2Y1P4 PTHR10671:SF96 EPITHELIAL MEMBRANE PROTEIN-RELATED CLC-LIKE PROTEIN 5 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cytoskeletal protein#PC00085 CIOIN|Ensembl=ENSCING00000014326.2|UniProtKB=F6TZN8 F6TZN8 PTHR15911:SF6 WW DOMAIN-CONTAINING ADAPTER PROTEIN WITH COILED-COIL WW DOMAIN-CONTAINING ADAPTER PROTEIN WITH COILED-COIL basal RNA polymerase II transcription machinery binding#GO:0001099;RNA polymerase binding#GO:0070063;binding#GO:0005488;chromatin binding#GO:0003682;RNA polymerase core enzyme binding#GO:0043175;RNA polymerase II complex binding#GO:0000993;enzyme binding#GO:0019899;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;basal transcription machinery binding#GO:0001098 regulation of cell communication#GO:0010646;positive regulation of TORC1 signaling#GO:1904263;regulation of TORC1 signaling#GO:1903432;regulation of catabolic process#GO:0009894;positive regulation of signal transduction#GO:0009967;regulation of autophagy#GO:0010506;regulation of signaling#GO:0023051;regulation of cellular catabolic process#GO:0031329;regulation of intracellular signal transduction#GO:1902531;regulation of TOR signaling#GO:0032006;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;regulation of cellular process#GO:0050794;positive regulation of TOR signaling#GO:0032008;regulation of signal transduction#GO:0009966;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000014800.2|UniProtKB=F6UYN1 F6UYN1 PTHR22674:SF6 NTPASE, KAP FAMILY P-LOOP DOMAIN-CONTAINING 1 NTPASE KAP FAMILY P-LOOP DOMAIN-CONTAINING PROTEIN 1 CIOIN|Ensembl=ENSCING00000003141.3|UniProtKB=F6QJM4 F6QJM4 LOC100179396 PTHR10082:SF42 INTEGRIN BETA SUBUNIT INTEGRIN BETA-4 cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;integrin binding#GO:0005178;binding#GO:0005488;signaling receptor binding#GO:0005102 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cell adhesion mediated by integrin#GO:0033627;cell-cell adhesion#GO:0098609;cell motility#GO:0048870;cell adhesion#GO:0007155;cell communication#GO:0007154;cell-substrate adhesion#GO:0031589;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cell-matrix adhesion#GO:0007160;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;integrin-mediated signaling pathway#GO:0007229;cell migration#GO:0016477;signaling#GO:0023052 receptor complex#GO:0043235;membrane protein complex#GO:0098796;cell surface#GO:0009986;protein-containing complex#GO:0032991;plasma membrane signaling receptor complex#GO:0098802;anchoring junction#GO:0070161;plasma membrane protein complex#GO:0098797;focal adhesion#GO:0005925;cell junction#GO:0030054;cell-substrate junction#GO:0030055;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cell adhesion molecule#PC00069;integrin#PC00126 Integrin signalling pathway#P00034>Integrin beta#P00931 CIOIN|Ensembl=ENSCING00000006358.3|UniProtKB=F6RS75 F6RS75 LOC100187137 PTHR33588:SF1 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 299 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 299 structural protein#PC00211 CIOIN|Ensembl=ENSCING00000007529.3|UniProtKB=F6TVZ8 F6TVZ8 PTHR11937:SF155 ACTIN ACTIN-RELATED PROTEIN 1 actin and actin related protein#PC00039;cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 Nicotinic acetylcholine receptor signaling pathway#P00044>Actin#P01090 CIOIN|Ensembl=ENSCING00000015156.2|UniProtKB=F6ZSG1 F6ZSG1 LOC100186978 PTHR11785:SF512 AMINO ACID TRANSPORTER SOBREMESA, ISOFORM B L-amino acid transmembrane transporter activity#GO:0015179;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;amino acid transmembrane transporter activity#GO:0015171;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215;organic acid transmembrane transporter activity#GO:0005342 localization#GO:0051179;organic substance transport#GO:0071702;amino acid transmembrane transport#GO:0003333;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;amino acid transport#GO:0006865;organic anion transport#GO:0015711;organic acid transport#GO:0015849;transport#GO:0006810;nitrogen compound transport#GO:0071705;organic acid transmembrane transport#GO:1903825;carboxylic acid transport#GO:0046942;cellular process#GO:0009987;carboxylic acid transmembrane transport#GO:1905039 transporter#PC00227 CIOIN|Ensembl=ENSCING00000009142.3|UniProtKB=F6TJD9 F6TJD9 tgfbeta-na4 PTHR11848:SF119 TGF-BETA FAMILY TGF-BETA FAMILY PROFILE DOMAIN-CONTAINING PROTEIN molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;cytokine activity#GO:0005125;protein binding#GO:0005515;signaling receptor binding#GO:0005102 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 TGF-beta signaling pathway#P00052>TGFbeta#P01286 CIOIN|Ensembl=ENSCING00000008198.3|UniProtKB=F6PJX9 F6PJX9 LOC100182071 PTHR31531:SF2 E3 UBIQUITIN-PROTEIN LIGASE E3D FAMILY MEMBER E3 UBIQUITIN-PROTEIN LIGASE E3D ubiquitin-like protein conjugating enzyme binding#GO:0044390;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;enzyme binding#GO:0019899;protein binding#GO:0005515;aminoacyltransferase activity#GO:0016755;cyclin binding#GO:0030332;catalytic activity, acting on a protein#GO:0140096 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;protein monoubiquitination#GO:0006513;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein polyubiquitination#GO:0000209;proteasomal protein catabolic process#GO:0010498;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000023310.1|UniProtKB=H2XLY8 H2XLY8 PTHR15583:SF7 INTERLEUKIN-17 RECEPTOR INTERLEUKIN CYTOKINE RECEPTOR-RELATED PROTEIN 2 signaling receptor activity#GO:0038023;cytokine receptor activity#GO:0004896;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 transmembrane signal receptor#PC00197 CIOIN|Ensembl=ENSCING00000006124.3|UniProtKB=F6VS86 F6VS86 PTHR23195:SF27 YEATS DOMAIN ENL_AF9-RELATED, ISOFORM B protein binding#GO:0005515;histone binding#GO:0042393;binding#GO:0005488 protein-DNA complex organization#GO:0071824;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;cellular component organization#GO:0016043;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;protein-containing complex organization#GO:0043933;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;chromatin remodeling#GO:0006338;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 histone acetyltransferase complex#GO:0000123;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;acetyltransferase complex#GO:1902493;chromatin#GO:0000785;protein-DNA complex#GO:0032993;catalytic complex#GO:1902494;NuA4 histone acetyltransferase complex#GO:0035267;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein acetyltransferase complex#GO:0031248;protein-containing complex#GO:0032991;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227 general transcription factor#PC00259 CIOIN|Ensembl=ENSCING00000007051.3|UniProtKB=F6ZBX3 F6ZBX3 PTHR24260:SF136 FAMILY NOT NAMED GH08193P-RELATED CIOIN|Ensembl=ENSCING00000002417.3|UniProtKB=F6QHG7 F6QHG7 LOC100182362 PTHR14094:SF9 SIGNAL RECOGNITION PARTICLE 72 SIGNAL RECOGNITION PARTICLE SUBUNIT SRP72 ribonucleoprotein complex binding#GO:0043021;ribosome binding#GO:0043022;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;protein-containing complex binding#GO:0044877;binding#GO:0005488;organic cyclic compound binding#GO:0097159 localization within membrane#GO:0051668;cotranslational protein targeting to membrane#GO:0006613;cellular localization#GO:0051641;protein localization to endoplasmic reticulum#GO:0070972;macromolecule localization#GO:0033036;protein localization to membrane#GO:0072657;protein targeting#GO:0006605;protein targeting to ER#GO:0045047;establishment of protein localization to organelle#GO:0072594;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;SRP-dependent cotranslational protein targeting to membrane#GO:0006614;establishment of protein localization to membrane#GO:0090150;protein targeting to membrane#GO:0006612;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein localization to organelle#GO:0033365;establishment of protein localization to endoplasmic reticulum#GO:0072599 cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000008820.3|UniProtKB=F6UEB6 F6UEB6 soxh PTHR10270:SF161 SOX TRANSCRIPTION FACTOR SEX-DETERMINING REGION Y PROTEIN DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;cell differentiation#GO:0030154;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA metabolic process#GO:0051252;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;positive regulation of RNA metabolic process#GO:0051254;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;HMG box transcription factor#PC00024 CIOIN|Ensembl=ENSCING00000003205.3|UniProtKB=F6S3K3 F6S3K3 PTHR15654:SF2 COILED-COIL DOMAIN-CONTAINING PROTEIN 113-RELATED COILED-COIL DOMAIN-CONTAINING PROTEIN 113 organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cell projection organization#GO:0030030;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031 axoneme#GO:0005930;microtubule organizing center#GO:0005815;cytoplasmic region#GO:0099568;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;ciliary basal body#GO:0036064;ciliary plasm#GO:0097014;plasma membrane bounded cell projection cytoplasm#GO:0032838;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;cell projection#GO:0042995;cilium#GO:0005929 CIOIN|Ensembl=ENSCING00000021734.1|UniProtKB=H2XS65 H2XS65 PTHR20765:SF1 SOLUTE CARRIER FAMILY 43 MEMBER 3-RELATED EQUILIBRATIVE NUCLEOBASE TRANSPORTER 1 amino acid transporter#PC00046;secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000021331.1|UniProtKB=H2XNI9 H2XNI9 PTHR12219:SF8 NADH-UBIQUINONE OXIDOREDUCTASE NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 4, MITOCHONDRIAL oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000011553.2|UniProtKB=F6TC27 F6TC27 PTHR22572:SF104 SUGAR-1-PHOSPHATE GUANYL TRANSFERASE MANNOSE-1-PHOSPHATE GUANYLTRANSFERASE ALPHA transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 Mannose metabolism#P02752>Mannose 1-P guanylyl transferase#P03018 CIOIN|Ensembl=ENSCING00000005084.3|UniProtKB=F6ZKY0 F6ZKY0 LOC100185312 PTHR22406:SF7 NASCENT POLYPEPTIDE-ASSOCIATED COMPLEX SUBUNIT ALPHA, MUSCLE-SPECIFIC FORM NASCENT POLYPEPTIDE-ASSOCIATED COMPLEX SUBUNIT ALPHA, MUSCLE-SPECIFIC FORM regulation of microtubule-based process#GO:0032886;cellular component biogenesis#GO:0044085;positive regulation of organelle organization#GO:0010638;microtubule cytoskeleton organization#GO:0000226;protein-containing complex assembly#GO:0065003;regulation of cellular component organization#GO:0051128;microtubule polymerization or depolymerization#GO:0031109;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;regulation of protein-containing complex assembly#GO:0043254;microtubule polymerization#GO:0046785;regulation of cellular component biogenesis#GO:0044087;supramolecular fiber organization#GO:0097435;regulation of microtubule cytoskeleton organization#GO:0070507;cytoskeleton organization#GO:0007010;positive regulation of cellular component biogenesis#GO:0044089;regulation of protein polymerization#GO:0032271;positive regulation of biological process#GO:0048518;cytoplasmic microtubule organization#GO:0031122;cellular component assembly#GO:0022607;regulation of organelle organization#GO:0033043;cellular component organization#GO:0016043;regulation of microtubule polymerization or depolymerization#GO:0031110;cellular process#GO:0009987;positive regulation of protein polymerization#GO:0032273;positive regulation of cellular process#GO:0048522;regulation of supramolecular fiber organization#GO:1902903;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;regulation of cellular process#GO:0050794;protein-containing complex organization#GO:0043933;organelle organization#GO:0006996;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;protein polymerization#GO:0051258;microtubule nucleation#GO:0007020 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;microtubule plus-end#GO:0035371;intracellular organelle#GO:0043229;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000020057.1|UniProtKB=F6WC00 F6WC00 LOC100175166 PTHR34491:SF164 A-TYPE INCLUSION PROTEIN, PUTATIVE-RELATED HOLOCENTRIC CHROMOSOME BINDING PROTEIN-RELATED CIOIN|Ensembl=ENSCING00000025095.1|UniProtKB=H2XW79 H2XW79 LOC100184834 PTHR21683:SF3 COILED-COIL DOMAIN-CONTAINING PROTEIN 42 LIKE-2-LIKE-RELATED CILIA AND FLAGELLA ASSOCIATED PROTEIN 100 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 CIOIN|Ensembl=ENSCING00000009051.3|UniProtKB=F6R2L1 F6R2L1 LOC100185443 PTHR34639:SF1 PROTEIN FLATTOP PROTEIN FLATTOP cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782;cellular component organization#GO:0016043;cellular process#GO:0009987;cell projection organization#GO:0030030;organelle organization#GO:0006996;plasma membrane bounded cell projection organization#GO:0120036 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;microtubule cytoskeleton#GO:0015630;ciliary basal body#GO:0036064;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cilium#GO:0005929;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000014588.2|UniProtKB=A0A1W5BKL9 A0A1W5BKL9 LOC100175476 PTHR21508:SF5 MITOGUARDIN MITOGUARDIN mitochondrial fusion#GO:0008053;cellular component organization or biogenesis#GO:0071840;mitochondrion organization#GO:0007005;cellular component organization#GO:0016043;cellular process#GO:0009987;organelle organization#GO:0006996;organelle fusion#GO:0048284 CIOIN|Ensembl=ENSCING00000020515.1|UniProtKB=H2Y2I3 H2Y2I3 PTHR24250:SF50 CHYMOTRYPSIN-RELATED PEPTIDASE S1 DOMAIN-CONTAINING PROTEIN hydrolase activity#GO:0016787;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 serine protease#PC00203;protease#PC00190 CIOIN|Ensembl=ENSCING00000011322.2|UniProtKB=F6QQE0 F6QQE0 PTHR24020:SF87 COLLAGEN ALPHA COLLAGEN ALPHA-1(VI) CHAIN-LIKE external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 CIOIN|Ensembl=ENSCING00000011952.2|UniProtKB=F6UKJ4 F6UKJ4 LOC100181662 PTHR10671:SF108 EPITHELIAL MEMBRANE PROTEIN-RELATED CLAUDIN FAMILY PROTEIN-RELATED cytoskeletal protein#PC00085 CIOIN|Ensembl=ENSCING00000002428.3|UniProtKB=F6Q8W5 F6Q8W5 PTHR45628:SF7 VOLTAGE-DEPENDENT CALCIUM CHANNEL TYPE A SUBUNIT ALPHA-1 VOLTAGE-DEPENDENT CALCIUM CHANNEL TYPE A SUBUNIT ALPHA-1 calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;calcium channel activity#GO:0005262;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;transporter activity#GO:0005215;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated calcium channel activity#GO:0005245;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;calcium ion transmembrane transport#GO:0070588;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;calcium ion transport#GO:0006816;localization#GO:0051179;calcium ion import#GO:0070509;import across plasma membrane#GO:0098739;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;calcium ion transmembrane import into cytosol#GO:0097553;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;import into cell#GO:0098657 voltage-gated calcium channel complex#GO:0005891;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;calcium channel complex#GO:0034704;membrane#GO:0016020;cation channel complex#GO:0034703;plasma membrane#GO:0005886 transporter#PC00227;voltage-gated ion channel#PC00241 Ionotropic glutamate receptor pathway#P00037>Ca2+ channel#P01022;Thyrotropin-releasing hormone receptor signaling pathway#P04394>Ca2+ channel#P04587;Metabotropic glutamate receptor group II pathway#P00040>Ca2+#P01051;Metabotropic glutamate receptor group III pathway#P00039>Ca2+#P01041 CIOIN|Ensembl=ENSCING00000016455.2|UniProtKB=F6USM8 F6USM8 inx PTHR15759:SF6 PANNEXIN INNEXIN CIOIN|Ensembl=ENSCING00000008897.3|UniProtKB=F6QF10 F6QF10 LOC100175606 PTHR24058:SF17 DUAL SPECIFICITY PROTEIN KINASE HOMEODOMAIN INTERACTING PROTEIN KINASE, ISOFORM D protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;protein phosphorylation#GO:0006468;cellular process#GO:0009987;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;peptidyl-threonine phosphorylation#GO:0018107;nitrogen compound metabolic process#GO:0006807;peptidyl-serine modification#GO:0018209;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000023509.1|UniProtKB=H2Y0M1 H2Y0M1 LOC113474977 PTHR22552:SF25 GEO11429P1 GEO11429P1 CIOIN|Ensembl=ENSCING00000009639.3|UniProtKB=F6ZTX9 F6ZTX9 PTHR13069:SF21 ALKYLATED DNA REPAIR PROTEIN ALKB HOMOLOG 8 ALKYLATED DNA REPAIR PROTEIN ALKB HOMOLOG 8 CIOIN|Ensembl=ENSCING00000003292.3|UniProtKB=F7A4P8 F7A4P8 PTHR43028:SF3 3'(2'),5'-BISPHOSPHATE NUCLEOTIDASE 1 INOSITOL POLYPHOSPHATE 1-PHOSPHATASE hydrolase activity#GO:0016787;inositol phosphate phosphatase activity#GO:0052745;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 phosphatase#PC00181;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000011317.2|UniProtKB=A0A1W2W027 A0A1W2W027 LOC100184259 PTHR13145:SF0 SSM4 PROTEIN E3 UBIQUITIN-PROTEIN LIGASE MARCHF6 response to organic substance#GO:0010033;macromolecule catabolic process#GO:0009057;cellular response to stimulus#GO:0051716;response to endoplasmic reticulum stress#GO:0034976;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;response to organonitrogen compound#GO:0010243;ERAD pathway#GO:0036503;cellular process#GO:0009987;primary metabolic process#GO:0044238;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;cellular response to stress#GO:0033554;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000018288.1|UniProtKB=H2XQT1 H2XQT1 PTHR22526:SF2 ANAPHASE PROMOTING COMPLEX C SUBUNIT 15, PSEUDOGENE-RELATED ANAPHASE PROMOTING COMPLEX C SUBUNIT 15, PSEUDOGENE-RELATED regulation of chromosome organization#GO:0033044;regulation of cell communication#GO:0010646;regulation of mitotic nuclear division#GO:0007088;regulation of mitotic sister chromatid separation#GO:0010965;regulation of chromosome segregation#GO:0051983;regulation of nuclear division#GO:0051783;regulation of mitotic cell cycle phase transition#GO:1901990;regulation of organelle organization#GO:0033043;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;regulation of chromosome separation#GO:1905818;regulation of signaling#GO:0023051;regulation of cell cycle phase transition#GO:1901987;regulation of cellular component organization#GO:0051128;regulation of intracellular signal transduction#GO:1902531;regulation of mitotic metaphase/anaphase transition#GO:0030071;regulation of cell cycle process#GO:0010564;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of mitotic sister chromatid segregation#GO:0033047;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;regulation of sister chromatid segregation#GO:0033045;regulation of mitotic cell cycle#GO:0007346 ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cullin-RING ubiquitin ligase complex#GO:0031461;catalytic complex#GO:1902494;transferase complex#GO:1990234;anaphase-promoting complex#GO:0005680;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;nuclear ubiquitin ligase complex#GO:0000152;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 CIOIN|Ensembl=ENSCING00000001265.3|UniProtKB=Q95P33 Q95P33 Ci-opsin1 PTHR24240:SF192 OPSIN C-TYPE OPSIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 response to light stimulus#GO:0009416;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;detection of stimulus#GO:0051606;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;regulation of cellular process#GO:0050794;response to radiation#GO:0009314;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;response to abiotic stimulus#GO:0009628;signaling#GO:0023052;cellular response to light stimulus#GO:0071482 9+0 non-motile cilium#GO:0097731;non-motile cilium#GO:0097730;neuron projection#GO:0043005;photoreceptor outer segment#GO:0001750;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;cilium#GO:0005929;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 CIOIN|Ensembl=ENSCING00000014710.2|UniProtKB=F6ZC01 F6ZC01 PTHR11086:SF18 DEOXYCYTIDYLATE DEAMINASE-RELATED DEOXYCYTIDYLATE DEAMINASE hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;deaminase activity#GO:0019239;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;nucleoside metabolic process#GO:0009116;glycosyl compound catabolic process#GO:1901658;carbohydrate derivative metabolic process#GO:1901135;heterocycle catabolic process#GO:0046700;pyrimidine-containing compound metabolic process#GO:0072527;organonitrogen compound catabolic process#GO:1901565;nucleobase-containing compound metabolic process#GO:0006139;cellular nitrogen compound catabolic process#GO:0044270;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;catabolic process#GO:0009056;nucleoside catabolic process#GO:0009164;organic substance catabolic process#GO:1901575;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248;heterocycle metabolic process#GO:0046483;carbohydrate derivative catabolic process#GO:1901136;cellular metabolic process#GO:0044237;organonitrogen compound metabolic process#GO:1901564;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;small molecule catabolic process#GO:0044282;aromatic compound catabolic process#GO:0019439;nucleobase-containing small molecule catabolic process#GO:0034656;organic cyclic compound catabolic process#GO:1901361;nucleobase-containing compound catabolic process#GO:0034655;glycosyl compound metabolic process#GO:1901657;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 deaminase#PC00088;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000024137.1|UniProtKB=F6SLI9 F6SLI9 LOC100176601 PTHR22802:SF396 C-TYPE LECTIN SUPERFAMILY MEMBER C-TYPE LECTIN DOMAIN-CONTAINING PROTEIN membrane traffic protein#PC00150 CIOIN|Ensembl=ENSCING00000023991.1|UniProtKB=H2XLS7 H2XLS7 LOC100187325 PTHR15371:SF0 TIM23 SD19278P protein transmembrane transporter activity#GO:0008320;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 cellular localization#GO:0051641;transmembrane transport#GO:0055085;macromolecule localization#GO:0033036;transport#GO:0006810;protein transmembrane transport#GO:0071806;protein targeting#GO:0006605;nitrogen compound transport#GO:0071705;establishment of protein localization to organelle#GO:0072594;protein localization to mitochondrion#GO:0070585;cellular process#GO:0009987;protein transmembrane import into intracellular organelle#GO:0044743;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;mitochondrial transport#GO:0006839;organic substance transport#GO:0071702;protein import into mitochondrial matrix#GO:0030150;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein targeting to mitochondrion#GO:0006626;establishment of protein localization to mitochondrion#GO:0072655;protein transport#GO:0015031;protein localization to organelle#GO:0033365;mitochondrial transmembrane transport#GO:1990542 envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;TIM23 mitochondrial import inner membrane translocase complex#GO:0005744;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial envelope#GO:0005740;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227;mitochondrial protein-containing complex#GO:0098798 amino acid transporter#PC00046;transporter#PC00227 CIOIN|Ensembl=ENSCING00000018512.1|UniProtKB=H2XWH1 H2XWH1 LOC100180531 PTHR10915:SF1 SYNDECAN SYNDECAN cell motility#GO:0048870;cellular process#GO:0009987;cell migration#GO:0016477 cell surface#GO:0009986;cellular anatomical entity#GO:0110165 transmembrane signal receptor#PC00197 CIOIN|Ensembl=ENSCING00000003759.3|UniProtKB=F6U6C0 F6U6C0 PTHR21600:SF83 MITOCHONDRIAL RNA PSEUDOURIDINE SYNTHASE PSEUDOURIDYLATE SYNTHASE RPUSD4, MITOCHONDRIAL RNA metabolism protein#PC00031;RNA processing factor#PC00147 CIOIN|Ensembl=ENSCING00000005088.3|UniProtKB=F6WKV2 F6WKV2 PTHR15036:SF89 PIKACHURIN-LIKE PROTEIN NEUREXIN 1, ISOFORM F cell adhesion molecule#PC00069 CIOIN|Ensembl=ENSCING00000008122.3|UniProtKB=F6YM72 F6YM72 LOC100177988 PTHR18849:SF4 LEUCINE RICH REPEAT PROTEIN GENE 29133-RELATED CIOIN|Ensembl=ENSCING00000023295.1|UniProtKB=H2XW59 H2XW59 PTHR13101:SF1 PHOSPHOMEVALONATE KINASE PHOSPHOMEVALONATE KINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;phosphotransferase activity, phosphate group as acceptor#GO:0016776 sterol metabolic process#GO:0016125;cellular aromatic compound metabolic process#GO:0006725;lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;phospholipid biosynthetic process#GO:0008654;organophosphate biosynthetic process#GO:0090407;alcohol biosynthetic process#GO:0046165;cholesterol biosynthetic process#GO:0006695;cholesterol metabolic process#GO:0008203;organic hydroxy compound biosynthetic process#GO:1901617;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;lipid biosynthetic process#GO:0008610;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;steroid metabolic process#GO:0008202;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;secondary alcohol biosynthetic process#GO:1902653;secondary alcohol metabolic process#GO:1902652;amide metabolic process#GO:0043603;purine nucleotide metabolic process#GO:0006163;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;organic hydroxy compound metabolic process#GO:1901615;heterocycle metabolic process#GO:0046483;acyl-CoA metabolic process#GO:0006637;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;alcohol metabolic process#GO:0006066;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;isoprenoid metabolic process#GO:0006720;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;isoprenoid biosynthetic process#GO:0008299;organophosphate metabolic process#GO:0019637;small molecule biosynthetic process#GO:0044283;cellular lipid metabolic process#GO:0044255;nucleotide metabolic process#GO:0009117;steroid biosynthetic process#GO:0006694;sterol biosynthetic process#GO:0016126;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 kinase#PC00137 Cholesterol biosynthesis#P00014>Phosphomevalonate kinase#P00500 CIOIN|Ensembl=ENSCING00000023558.1|UniProtKB=H2XTM8 H2XTM8 PTHR19325:SF560 COMPLEMENT COMPONENT-RELATED SUSHI DOMAIN-CONTAINING SUSHI, VON WILLEBRAND FACTOR TYPE A, EGF AND PENTRAXIN DOMAIN-CONTAINING PROTEIN 1 complement component#PC00078 CIOIN|Ensembl=ENSCING00000022310.1|UniProtKB=H2XK31 H2XK31 ets_pointed1 PTHR11849:SF289 ETS ETS-LIKE PROTEIN POINTED transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 PDGF signaling pathway#P00047>Ets#P01167 CIOIN|Ensembl=ENSCING00000007584.3|UniProtKB=F7BGY7 F7BGY7 PTHR23065:SF57 PROLINE-SERINE-THREONINE PHOSPHATASE INTERACTING PROTEIN 1 GROWTH ARREST-SPECIFIC PROTEIN 7 cellular component biogenesis#GO:0044085;neurogenesis#GO:0022008;cell projection organization#GO:0030030;transport#GO:0006810;developmental process#GO:0032502;protein-containing complex assembly#GO:0065003;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cellular anatomical entity morphogenesis#GO:0032989;system development#GO:0048731;cell differentiation#GO:0030154;establishment of localization#GO:0051234;anatomical structure morphogenesis#GO:0009653;neuron differentiation#GO:0030182;receptor-mediated endocytosis#GO:0006898;plasma membrane bounded cell projection morphogenesis#GO:0120039;cellular developmental process#GO:0048869;cellular component assembly#GO:0022607;clathrin-dependent endocytosis#GO:0072583;multicellular organism development#GO:0007275;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell morphogenesis#GO:0000902;cellular process#GO:0009987;localization#GO:0051179;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;protein-containing complex organization#GO:0043933;anatomical structure development#GO:0048856;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;import into cell#GO:0098657 intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;coated vesicle#GO:0030135;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;clathrin-coated vesicle#GO:0030136;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;clathrin-coated pit#GO:0005905;plasma membrane#GO:0005886 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 CIOIN|Ensembl=ENSCING00000020807.1|UniProtKB=H2XXR8 H2XXR8 PTHR11216:SF166 EH DOMAIN DYNAMIN N-TERMINAL DOMAIN-CONTAINING PROTEIN localization#GO:0051179;endosomal transport#GO:0016197;cellular localization#GO:0051641;establishment of localization#GO:0051234;transport#GO:0006810;endocytosis#GO:0006897;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;cellular process#GO:0009987;import into cell#GO:0098657 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 membrane traffic protein#PC00150 CIOIN|Ensembl=ENSCING00000017064.2|UniProtKB=F6X245 F6X245 PTHR11783:SF43 SULFOTRANSFERASE SULT AMINE SULFOTRANSFERASE-RELATED sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824 cellular metabolic process#GO:0044237;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000002936.3|UniProtKB=F7BIM6 F7BIM6 LOC100178689 PTHR23220:SF133 INTEGRIN ALPHA INTEGRIN ALPHA-PS2 cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;integrin binding#GO:0005178;binding#GO:0005488;signaling receptor binding#GO:0005102 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cell adhesion mediated by integrin#GO:0033627;cell-cell adhesion#GO:0098609;cell communication#GO:0007154;cell adhesion#GO:0007155;cell-substrate adhesion#GO:0031589;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cell-matrix adhesion#GO:0007160;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;integrin-mediated signaling pathway#GO:0007229;biological regulation#GO:0065007;signaling#GO:0023052 receptor complex#GO:0043235;membrane protein complex#GO:0098796;external side of plasma membrane#GO:0009897;cell surface#GO:0009986;protein-containing complex#GO:0032991;plasma membrane signaling receptor complex#GO:0098802;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 cell adhesion molecule#PC00069;integrin#PC00126 Integrin signalling pathway#P00034>Integrin alpha#P00941 CIOIN|Ensembl=ENSCING00000014934.2|UniProtKB=F6Y6W3 F6Y6W3 LOC100182394 PTHR21321:SF4 PNAS-3 RELATED EXOSOME COMPLEX COMPONENT RRP4 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159 negative regulation of gene expression#GO:0010629;cellular component biogenesis#GO:0044085;regulation of catabolic process#GO:0009894;heterocycle catabolic process#GO:0046700;regulation of nitrogen compound metabolic process#GO:0051171;rRNA processing#GO:0006364;positive regulation of cellular metabolic process#GO:0031325;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;RNA destabilization#GO:0050779;regulation of biological process#GO:0050789;ncRNA metabolic process#GO:0034660;mRNA metabolic process#GO:0016071;regulation of biological quality#GO:0065008;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;snRNA 3'-end processing#GO:0034472;ribosome biogenesis#GO:0042254;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;regulation of RNA stability#GO:0043487;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;positive regulation of mRNA catabolic process#GO:0061014;regulation of cellular process#GO:0050794;rRNA metabolic process#GO:0016072;post-transcriptional regulation of gene expression#GO:0010608;positive regulation of catabolic process#GO:0009896;mRNA destabilization#GO:0061157;nucleobase-containing compound catabolic process#GO:0034655;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of mRNA stability#GO:0043488;regulation of mRNA catabolic process#GO:0061013;RNA metabolic process#GO:0016070;positive regulation of cellular catabolic process#GO:0031331;RNA processing#GO:0006396;biosynthetic process#GO:0009058;cellular nitrogen compound catabolic process#GO:0044270;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;mRNA catabolic process#GO:0006402;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;snRNA processing#GO:0016180;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance catabolic process#GO:1901575;maturation of 5.8S rRNA#GO:0000460;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;positive regulation of mRNA metabolic process#GO:1903313;heterocycle metabolic process#GO:0046483;snRNA metabolic process#GO:0016073;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;RNA 3'-end processing#GO:0031123;cellular biosynthetic process#GO:0044249;nuclear-transcribed mRNA catabolic process#GO:0000956;organic substance biosynthetic process#GO:1901576;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;aromatic compound catabolic process#GO:0019439;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;ribonucleoprotein complex biogenesis#GO:0022613;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;positive regulation of RNA metabolic process#GO:0051254 cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;exosome (RNase complex)#GO:0000178;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622 RNA processing factor#PC00147 CIOIN|Ensembl=ENSCING00000023587.1|UniProtKB=F6QJ74 F6QJ74 LOC100175450 PTHR10961:SF46 PEROXISOMAL SARCOSINE OXIDASE PEROXISOMAL SARCOSINE OXIDASE oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 oxidase#PC00175;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000021103.1|UniProtKB=H2Y247 H2Y247 LOC100179332 PTHR11036:SF127 SEMAPHORIN SEMAPHORIN-1A molecular function activator activity#GO:0140677;binding#GO:0005488;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;protein binding#GO:0005515;signaling receptor binding#GO:0005102 cellular developmental process#GO:0048869;regulation of cell motility#GO:2000145;regulation of locomotion#GO:0040012;stem cell development#GO:0048864;animal organ development#GO:0048513;neural crest cell development#GO:0014032;developmental process#GO:0032502;positive regulation of locomotion#GO:0040017;ameboidal-type cell migration#GO:0001667;cell motility#GO:0048870;cellular process#GO:0009987;tissue development#GO:0009888;mesenchymal cell differentiation#GO:0048762;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;cell development#GO:0048468;cell differentiation#GO:0030154;regulation of cell migration#GO:0030334;positive regulation of cell migration#GO:0030335;neural crest cell differentiation#GO:0014033;regulation of cellular process#GO:0050794;mesenchyme development#GO:0060485;anatomical structure development#GO:0048856;positive regulation of cell motility#GO:2000147;biological regulation#GO:0065007;stem cell differentiation#GO:0048863;neural crest cell migration#GO:0001755;cell migration#GO:0016477;positive regulation of biological process#GO:0048518 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 membrane-bound signaling molecule#PC00152;intercellular signal molecule#PC00207 CIOIN|Ensembl=ENSCING00000004600.3|UniProtKB=F6WPA1 F6WPA1 PTHR48041:SF139 ABC TRANSPORTER G FAMILY MEMBER 28 PROTEIN SCARLET transmembrane transporter activity#GO:0022857;primary active transmembrane transporter activity#GO:0015399;ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 localization#GO:0051179;establishment of localization#GO:0051234;cellular process#GO:0009987;transmembrane transport#GO:0055085;transport#GO:0006810 cellular anatomical entity#GO:0110165;membrane#GO:0016020 ATP-binding cassette (ABC) transporter#PC00003;transporter#PC00227 CIOIN|Ensembl=ENSCING00000006233.3|UniProtKB=F6YVF5 F6YVF5 LOC100181538 PTHR23050:SF417 CALCIUM BINDING PROTEIN CALMODULIN-LIKE PROTEIN 6 cation binding#GO:0043169;small molecule binding#GO:0036094;molecular function regulator activity#GO:0098772;binding#GO:0005488;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;enzyme regulator activity#GO:0030234 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 calmodulin-related#PC00061 CIOIN|Ensembl=ENSCING00000022119.1|UniProtKB=H2XNQ6 H2XNQ6 LOC100187358 PTHR10671:SF108 EPITHELIAL MEMBRANE PROTEIN-RELATED CLAUDIN FAMILY PROTEIN-RELATED cytoskeletal protein#PC00085 CIOIN|Ensembl=ENSCING00000011652.2|UniProtKB=F6ZN07 F6ZN07 PTHR16146:SF46 INTELECTIN INTELECTIN-1A-RELATED CIOIN|Ensembl=ENSCING00000011412.2|UniProtKB=F7AXF4 F7AXF4 PTHR24256:SF570 TRYPTASE-RELATED CLIP-DOMAIN SERINE PROTEASE hydrolase activity#GO:0016787;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 serine protease#PC00203;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000023060.1|UniProtKB=H2XS39 H2XS39 PTHR10151:SF114 ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE ECTONUCLEOTIDE PYROPHOSPHATASE_PHOSPHODIESTERASE C27A7.3 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000018615.1|UniProtKB=H2XPT9 H2XPT9 PTHR10516:SF443 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FK506-BINDING PROTEIN 59-RELATED chaperone#PC00072 TGF-beta signaling pathway#P00052>FKBP12#P01288 CIOIN|Ensembl=ENSCING00000002914.3|UniProtKB=F6SCC6 F6SCC6 PTHR20003:SF7 GLYCOPROTEIN-RELATED SGNH DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000009383.3|UniProtKB=F6WBF5 F6WBF5 PTHR48408:SF1 FAMILY NOT NAMED XYLOSE ISOMERASE CIOIN|Ensembl=ENSCING00000016291.2|UniProtKB=F6W573 F6W573 PTHR14002:SF20 ENDOGLIN/TGF-BETA RECEPTOR TYPE III ZONA PELLUCIDA-LIKE DOMAIN-CONTAINING PROTEIN 1 transmembrane signal receptor#PC00197 CIOIN|Ensembl=ENSCING00000020810.1|UniProtKB=H2Y364 H2Y364 PTHR34490:SF1 PROTEIN CBG12054-RELATED GALAXIN-LIKE CIOIN|Ensembl=ENSCING00000019039.1|UniProtKB=H2XJF8 H2XJF8 PTHR45996:SF3 AGAP001464-PB CREB-H TRANSCRIPTION FACTOR HOMOLOG LET-607 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 Transcription regulation by bZIP transcription factor#P00055>CREB#P01383 CIOIN|Ensembl=ENSCING00000015312.2|UniProtKB=F7B819 F7B819 PTHR23405:SF5 MAINTENANCE OF KILLER 16 MAK16 PROTEIN-RELATED THO COMPLEX SUBUNIT 7 HOMOLOG mRNA export from nucleus#GO:0006406;cellular localization#GO:0051641;macromolecule biosynthetic process#GO:0009059;macromolecule localization#GO:0033036;establishment of RNA localization#GO:0051236;macromolecule metabolic process#GO:0043170;transport#GO:0006810;nucleic acid transport#GO:0050657;nitrogen compound transport#GO:0071705;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;mRNA transport#GO:0051028;RNA localization#GO:0006403;localization#GO:0051179;organic substance transport#GO:0071702;nuclear export#GO:0051168;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;RNA transport#GO:0050658;nucleobase-containing compound transport#GO:0015931;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;nuclear transport#GO:0051169;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;THO complex#GO:0000347;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;transcription export complex#GO:0000346;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000003122.3|UniProtKB=F6RCR0 F6RCR0 PTHR12670:SF1 CERAMIDASE NEUTRAL CERAMIDASE hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;alcohol biosynthetic process#GO:0046165;organonitrogen compound catabolic process#GO:1901565;organic hydroxy compound biosynthetic process#GO:1901617;lipid catabolic process#GO:0016042;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;sphingolipid metabolic process#GO:0006665;carboxylic acid biosynthetic process#GO:0046394;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;sphingolipid catabolic process#GO:0030149;cellular lipid catabolic process#GO:0044242;amide metabolic process#GO:0043603;sphingolipid biosynthetic process#GO:0030148;fatty acid biosynthetic process#GO:0006633;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;long-chain fatty acid metabolic process#GO:0001676;organic hydroxy compound metabolic process#GO:1901615;organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;monocarboxylic acid biosynthetic process#GO:0072330;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;alcohol metabolic process#GO:0006066;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;membrane lipid biosynthetic process#GO:0046467;monocarboxylic acid metabolic process#GO:0032787;ceramide metabolic process#GO:0006672;primary metabolic process#GO:0044238;fatty acid metabolic process#GO:0006631;membrane lipid metabolic process#GO:0006643;small molecule biosynthetic process#GO:0044283;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281 cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 CIOIN|Ensembl=ENSCING00000000924.3|UniProtKB=F6U019 F6U019 LOC100175935 PTHR10589:SF16 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE ISOZYME L5 cysteine-type peptidase activity#GO:0008234;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;cysteine-type deubiquitinase activity#GO:0004843 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;protein modification by small protein removal#GO:0070646;protein deubiquitination#GO:0016579;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 cysteine protease#PC00081;protease#PC00190 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489 CIOIN|Ensembl=ENSCING00000023607.1|UniProtKB=H2XVT2 H2XVT2 PTHR13826:SF14 INTESTINAL TREFOIL FACTOR-RELATED TREFOIL FACTOR 2 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 CIOIN|Ensembl=ENSCING00000002730.3|UniProtKB=F6TPA2 F6TPA2 LOC100184779 PTHR12786:SF2 SPLICING FACTOR SF3A-RELATED SPLICING FACTOR 3A SUBUNIT 3 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA splicing factor#PC00148;RNA processing factor#PC00147;RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000022791.1|UniProtKB=F6X972 F6X972 PTHR46771:SF5 DETERIN DETERIN CIOIN|Ensembl=ENSCING00000008757.2|UniProtKB=F6T0B7 F6T0B7 LOC100180966 PTHR23147:SF270 SERINE/ARGININE RICH SPLICING FACTOR RNA-BINDING PROTEIN RNP-1 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;nuclear speck#GO:0016607;organelle#GO:0043226;nuclear body#GO:0016604;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA splicing factor#PC00148;RNA processing factor#PC00147;RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000008073.3|UniProtKB=F6ZG55 F6ZG55 PTHR24388:SF90 ZINC FINGER PROTEIN C2H2-TYPE DOMAIN-CONTAINING PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 CIOIN|Ensembl=ENSCING00000006215.3|UniProtKB=F6XJU3 F6XJU3 PTHR45748:SF7 1-PHOSPHATIDYLINOSITOL 3-PHOSPHATE 5-KINASE-RELATED 1-PHOSPHATIDYLINOSITOL 3-PHOSPHATE 5-KINASE-RELATED transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301;lipid kinase activity#GO:0001727 lipid metabolic process#GO:0006629;phospholipid biosynthetic process#GO:0008654;organophosphate biosynthetic process#GO:0090407;phosphatidylinositol biosynthetic process#GO:0006661;glycerolipid biosynthetic process#GO:0045017;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;phosphatidylinositol metabolic process#GO:0046488;glycerophospholipid metabolic process#GO:0006650;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;phosphatidylinositol phosphate biosynthetic process#GO:0046854;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;glycerophospholipid biosynthetic process#GO:0046474;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 bounding membrane of organelle#GO:0098588;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endosome membrane#GO:0010008;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle membrane#GO:0030659 kinase#PC00137 CIOIN|Ensembl=ENSCING00000011528.2|UniProtKB=F6W804 F6W804 PTHR10983:SF16 1-ACYLGLYCEROL-3-PHOSPHATE ACYLTRANSFERASE-RELATED LYSOCARDIOLIPIN ACYLTRANSFERASE 1 acyltransferase#PC00042 CIOIN|Ensembl=ENSCING00000006389.3|UniProtKB=F6RJZ1 F6RJZ1 LOC100184120 PTHR22932:SF1 TELOMERASE-BINDING PROTEIN P23 HSP90 CO-CHAPERONE CO-CHAPERONE PROTEIN DAF-41 heat shock protein binding#GO:0031072;protein binding#GO:0005515;protein-folding chaperone binding#GO:0051087;binding#GO:0005488;Hsp90 protein binding#GO:0051879 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein-containing complex assembly#GO:0065003;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;chaperone-mediated protein complex assembly#GO:0051131;cellular biosynthetic process#GO:0044249;cellular component organization#GO:0016043;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;protein folding#GO:0006457;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chaperone#PC00072 CIOIN|Ensembl=ENSCING00000005640.3|UniProtKB=F7A8T7 F7A8T7 ikk-epsilon PTHR22969:SF15 IKB KINASE FI05319P transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;peptidyl-amino acid modification#GO:0018193;cellular process#GO:0009987;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;nitrogen compound metabolic process#GO:0006807;peptidyl-serine modification#GO:0018209;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000006058.3|UniProtKB=F6ZZ57 F6ZZ57 LOC100186990 PTHR11214:SF283 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE N-ACETYLLACTOSAMINIDE BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE 4-LIKE transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;protein O-linked glycosylation#GO:0006493;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 bounding membrane of organelle#GO:0098588;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;Golgi membrane#GO:0000139;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111 CIOIN|Ensembl=ENSCING00000004783.4|UniProtKB=F6RK88 F6RK88 LOC100176504 PTHR12747:SF0 ELONGATOR COMPLEX PROTEIN 1 ELONGATOR COMPLEX PROTEIN 1 tRNA binding#GO:0000049;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA modification#GO:0009451;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;tRNA modification#GO:0006400;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;tRNA wobble uridine modification#GO:0002098;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 elongator holoenzyme complex#GO:0033588;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031;general transcription factor#PC00259 PDGF signaling pathway#P00047>Ikk#P01146 CIOIN|Ensembl=ENSCING00000020578.1|UniProtKB=H2XQT4 H2XQT4 PTHR19134:SF562 RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE PROTEIN-TYROSINE-PHOSPHATASE hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;protein tyrosine phosphatase activity#GO:0004725;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 protein phosphatase#PC00195;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000021959.1|UniProtKB=H2XWS8 H2XWS8 PTHR24034:SF205 EGF-LIKE DOMAIN-CONTAINING PROTEIN NIDOGEN extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 CIOIN|Ensembl=ENSCING00000006263.3|UniProtKB=F6RRU7 F6RRU7 PTHR10201:SF331 MATRIX METALLOPROTEINASE MATRIX METALLOPROTEINASE-14-LIKE ISOFORM X1 hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular component organization or biogenesis#GO:0071840;extracellular structure organization#GO:0043062;external encapsulating structure organization#GO:0045229;catabolic process#GO:0009056;cellular component organization#GO:0016043;cellular process#GO:0009987;extracellular matrix organization#GO:0030198;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000001131.3|UniProtKB=Q6XLI4 Q6XLI4 rbm12 PTHR13976:SF88 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN-RELATED FI22004P1 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nitrogen compound metabolic process#GO:0051171;regulation of biosynthetic process#GO:0009889;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA splicing factor#PC00148;RNA processing factor#PC00147;RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000005764.3|UniProtKB=F6PTX7 F6PTX7 PTHR24251:SF30 OVOCHYMASE-RELATED MEMBRANE FRIZZLED-RELATED PROTEIN serine protease#PC00203;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000003982.3|UniProtKB=F6WJQ0 F6WJQ0 PTHR11726:SF10 60S RIBOSOMAL PROTEIN L10 LARGE RIBOSOMAL SUBUNIT PROTEIN UL16 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;cellular process#GO:0009987;ribosomal large subunit biogenesis#GO:0042273;organelle assembly#GO:0070925;protein-RNA complex assembly#GO:0022618;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;organelle organization#GO:0006996;ribosomal large subunit assembly#GO:0000027;ribonucleoprotein complex biogenesis#GO:0022613;protein-RNA complex organization#GO:0071826;ribosome biogenesis#GO:0042254;non-membrane-bounded organelle assembly#GO:0140694 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic large ribosomal subunit#GO:0022625;large ribosomal subunit#GO:0015934;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000005445.3|UniProtKB=F6UUV5 F6UUV5 PTHR13799:SF13 NGG1 INTERACTING FACTOR 3 NIF3-LIKE PROTEIN 1 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000023853.1|UniProtKB=H2XRR2 H2XRR2 LOC100176990 PTHR19282:SF519 TETRASPANIN TETRASPANIN cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000018871.1|UniProtKB=H2XSQ8 H2XSQ8 PTHR10792:SF1 60S RIBOSOMAL PROTEIN L24 RIBOSOMAL PROTEIN L24 ribosomal protein#PC00202;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000008989.3|UniProtKB=Q1RPV0 Q1RPV0 Ci-ZF(RING)-26 PTHR13363:SF6 RING FINGER AND SRY DOMAIN-CONTAINING RING FINGER AND SPRY DOMAIN-CONTAINING PROTEIN 1 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787 macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;catabolic process#GO:0009056;organonitrogen compound catabolic process#GO:1901565;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000013034.2|UniProtKB=F6TTC3 F6TTC3 PTHR47186:SF61 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 57 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 57-RELATED CIOIN|Ensembl=ENSCING00000004117.3|UniProtKB=F6XUP6 F6XUP6 PTHR22957:SF502 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN SMALL G PROTEIN SIGNALING MODULATOR 2-RELATED nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 regulation of molecular function#GO:0065009;regulation of GTPase activity#GO:0043087;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;activation of GTPase activity#GO:0090630;biological regulation#GO:0065007;positive regulation of molecular function#GO:0044093;regulation of hydrolase activity#GO:0051336;regulation of catalytic activity#GO:0050790;positive regulation of hydrolase activity#GO:0051345 GTPase-activating protein#PC00257 CIOIN|Ensembl=ENSCING00000002465.3|UniProtKB=F7B4P3 F7B4P3 PTHR23063:SF52 PHOSPHOLIPID ACYLTRANSFERASE LYSOPHOSPHATIDYLCHOLINE ACYLTRANSFERASE acyltransferase#PC00042 CIOIN|Ensembl=ENSCING00000020959.1|UniProtKB=H2XQU7 H2XQU7 PTHR16146:SF46 INTELECTIN INTELECTIN-1A-RELATED CIOIN|Ensembl=ENSCING00000021010.1|UniProtKB=H2XRX1 H2XRX1 LOC100177701 PTHR24193:SF128 ANKYRIN REPEAT PROTEIN GA-BINDING PROTEIN SUBUNIT BETA-1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of RNA metabolic process#GO:0051254;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000018067.1|UniProtKB=F6VKS9 F6VKS9 LOC100180021 PTHR11772:SF23 ASPARAGINE SYNTHETASE ASPARAGINE SYNTHETASE [GLUTAMINE-HYDROLYZING] ligase activity#GO:0016874;catalytic activity#GO:0003824 organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;proteinogenic amino acid metabolic process#GO:0170039;proteinogenic amino acid biosynthetic process#GO:0170038;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;aspartate family amino acid biosynthetic process#GO:0009067;alpha-amino acid biosynthetic process#GO:1901607;nitrogen compound metabolic process#GO:0006807;amino acid biosynthetic process#GO:0008652;alpha-amino acid metabolic process#GO:1901605;aspartate family amino acid metabolic process#GO:0009066;small molecule biosynthetic process#GO:0044283;L-amino acid biosynthetic process#GO:0170034;carboxylic acid metabolic process#GO:0019752;L-amino acid metabolic process#GO:0170033;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ligase#PC00142;metabolite interconversion enzyme#PC00262 Asparagine and aspartate biosynthesis#P02730>Asparagine synthetase#P02853 CIOIN|Ensembl=ENSCING00000013954.2|UniProtKB=F6RPT1 F6RPT1 PTHR11929:SF145 ALPHA- 1,3 -FUCOSYLTRANSFERASE ALPHA-(1,3)-FUCOSYLTRANSFERASE FUT-1 transferase activity#GO:0016740;fucosyltransferase activity#GO:0008417;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 glycosylation#GO:0070085;metabolic process#GO:0008152 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000009076.3|UniProtKB=F6QEV0 F6QEV0 LOC100184538 PTHR45954:SF1 LD33695P LD33695P nucleoside-triphosphatase regulator activity#GO:0060589;protein binding#GO:0005515;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;binding#GO:0005488;molecular function regulator activity#GO:0098772 establishment or maintenance of cell polarity#GO:0007163;cellular localization#GO:0051641;organelle localization#GO:0051640;establishment of spindle orientation#GO:0051294;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;cellular component organization#GO:0016043;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cellular process#GO:0009987;establishment of spindle localization#GO:0051293;mitotic cell cycle process#GO:1903047;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of mitotic spindle localization#GO:0040001;establishment of mitotic spindle orientation#GO:0000132;establishment of cell polarity#GO:0030010;mitotic cell cycle#GO:0000278;establishment of localization#GO:0051234;microtubule-based process#GO:0007017;organelle organization#GO:0006996;cell cycle#GO:0007049;establishment of localization in cell#GO:0051649;cytoskeleton organization#GO:0007010;establishment of organelle localization#GO:0051656;spindle localization#GO:0051653 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;cell cortex#GO:0005938;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000007637.3|UniProtKB=F6WI66 F6WI66 PTHR47958:SF32 ATP-DEPENDENT RNA HELICASE DBP3 RNA HELICASE nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 RNA helicase#PC00032 CIOIN|Ensembl=ENSCING00000007406.3|UniProtKB=F6RZ52 F6RZ52 PTHR16525:SF0 PROTEIN C12ORF4 PROTEIN C12ORF4 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000008349.3|UniProtKB=F7B404 F7B404 LOC100176500 PTHR45828:SF31 CYTOCHROME B561/FERRIC REDUCTASE TRANSMEMBRANE CYTOCHROME B561 DOMAIN-CONTAINING PROTEIN cellular anatomical entity#GO:0110165;membrane#GO:0016020 reductase#PC00198;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000001853.3|UniProtKB=F6T780 F6T780 LOC100182857 PTHR10024:SF348 SYNAPTOTAGMIN SYNAPTOTAGMIN-17 cation binding#GO:0043169;small molecule binding#GO:0036094;binding#GO:0005488;phosphatidylserine binding#GO:0001786;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;protein binding#GO:0005515;clathrin binding#GO:0030276;lipid binding#GO:0008289;ion binding#GO:0043167;phospholipid binding#GO:0005543;SNARE binding#GO:0000149 localization#GO:0051179;regulated exocytosis#GO:0045055;exocytosis#GO:0006887;establishment of localization#GO:0051234;secretion#GO:0046903;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;calcium-ion regulated exocytosis#GO:0017156;export from cell#GO:0140352;secretion by cell#GO:0032940 intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;transport vesicle#GO:0030133;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 membrane trafficking regulatory protein#PC00151 CIOIN|Ensembl=ENSCING00000007696.3|UniProtKB=F6SIM0 F6SIM0 PTHR22618:SF2 PROTEIN O-MANNOSE KINASE PROTEIN O-MANNOSE KINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;carbohydrate kinase activity#GO:0019200;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate phosphorylation#GO:0046835;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;protein O-linked glycosylation#GO:0006493;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;carbohydrate metabolic process#GO:0005975;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000020481.1|UniProtKB=H2XK69 H2XK69 LOC100183985 PTHR13007:SF19 PRE-MRNA SPLICING FACTOR-RELATED PRE-MRNA-SPLICING FACTOR 18 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;RNA processing#GO:0006396;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;protein-RNA complex assembly#GO:0022618;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;mRNA splicing, via spliceosome#GO:0000398;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;protein-containing complex organization#GO:0043933;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;ribonucleoprotein complex biogenesis#GO:0022613;mRNA processing#GO:0006397;protein-RNA complex organization#GO:0071826;RNA splicing, via transesterification reactions#GO:0000375 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;U4/U6 x U5 tri-snRNP complex#GO:0046540;U2-type spliceosomal complex#GO:0005684;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;U5 snRNP#GO:0005682;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;spliceosomal snRNP complex#GO:0097525;small nuclear ribonucleoprotein complex#GO:0030532;protein-containing complex#GO:0032991;spliceosomal tri-snRNP complex#GO:0097526;membrane-bounded organelle#GO:0043227;Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513 RNA splicing factor#PC00148;RNA processing factor#PC00147;RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000004361.3|UniProtKB=F6S5M6 F6S5M6 PTHR24033:SF224 EGF-LIKE DOMAIN-CONTAINING PROTEIN C-TYPE LECTIN CIOIN|Ensembl=ENSCING00000005752.3|UniProtKB=F6PZ24 F6PZ24 LOC100176919 PTHR22811:SF50 TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN 2 endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;Golgi organization#GO:0007030;macromolecule localization#GO:0033036;transport#GO:0006810;endomembrane system organization#GO:0010256;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;organelle organization#GO:0006996;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 COPII-coated ER to Golgi transport vesicle#GO:0030134;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;cellular anatomical entity#GO:0110165;organelle#GO:0043226;coated vesicle#GO:0030135;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;endoplasmic reticulum#GO:0005783;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793 vesicle coat protein#PC00235 CIOIN|Ensembl=ENSCING00000004254.3|UniProtKB=F6YFX5 F6YFX5 PTHR18945:SF916 NEUROTRANSMITTER GATED ION CHANNEL GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT BETA-LIKE inorganic molecular entity transmembrane transporter activity#GO:0015318;signaling receptor activity#GO:0038023;chloride channel activity#GO:0005254;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;molecular transducer activity#GO:0060089;chloride transmembrane transporter activity#GO:0015108;monoatomic anion transmembrane transporter activity#GO:0008509;inorganic anion transmembrane transporter activity#GO:0015103;transporter activity#GO:0005215;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267;transmembrane signaling receptor activity#GO:0004888 ligand-gated ion channel#PC00141;ion channel#PC00133;transporter#PC00227 CIOIN|Ensembl=ENSCING00000019976.1|UniProtKB=F6XEX3 F6XEX3 PTHR45847:SF6 FATTY ACID AMIDE HYDROLASE FATTY ACID AMIDE HYDROLASE hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;oxoacid metabolic process#GO:0043436;cellular metabolic process#GO:0044237;lipid catabolic process#GO:0016042;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;fatty acid catabolic process#GO:0009062;primary metabolic process#GO:0044238;fatty acid metabolic process#GO:0006631;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;cellular lipid metabolic process#GO:0044255;carboxylic acid catabolic process#GO:0046395;carboxylic acid metabolic process#GO:0019752;cellular lipid catabolic process#GO:0044242;monocarboxylic acid catabolic process#GO:0072329;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000013363.2|UniProtKB=F6YWI2 F6YWI2 LOC100182504 PTHR13296:SF0 BCAS2 PROTEIN PRE-MRNA-SPLICING FACTOR SPF27 ribonucleoprotein complex#GO:1990904;catalytic step 2 spliceosome#GO:0071013;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;precatalytic spliceosome#GO:0071011;cellular anatomical entity#GO:0110165;organelle#GO:0043226;Prp19 complex#GO:0000974;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622 RNA splicing factor#PC00148;RNA processing factor#PC00147;RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000007012.3|UniProtKB=F6VAL7 F6VAL7 PTHR10151:SF126 ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE ECTONUCLEOTIDE PYROPHOSPHATASE_PHOSPHODIESTERASE FAMILY MEMBER 7-LIKE metabolite interconversion enzyme#PC00262;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000000028.3|UniProtKB=F6WGY1 F6WGY1 PTHR20208:SF10 STRUCTURE-SPECIFIC ENDONUCLEASE SUBUNIT SLX1 STRUCTURE-SPECIFIC ENDONUCLEASE SUBUNIT SLX1 hydrolase activity, acting on ester bonds#GO:0016788;DNA endonuclease activity#GO:0004520;nuclease activity#GO:0004518;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a nucleic acid#GO:0140640;endonuclease activity#GO:0004519;DNA nuclease activity#GO:0004536;catalytic activity, acting on DNA#GO:0140097 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;double-strand break repair via homologous recombination#GO:0000724;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;response to stress#GO:0006950;nitrogen compound metabolic process#GO:0006807;recombinational repair#GO:0000725;cellular response to stress#GO:0033554;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 endodeoxyribonuclease#PC00093 Transcription regulation by bZIP transcription factor#P00055>RNA Polymerase II#P01388 CIOIN|Ensembl=ENSCING00000011815.2|UniProtKB=F7A536 F7A536 LOC100182239 PTHR23320:SF165 MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MS4A -RELATED MARVEL DOMAIN-CONTAINING PROTEIN transporter#PC00227 CIOIN|Ensembl=ENSCING00000020486.1|UniProtKB=F6X0N8 F6X0N8 LOC100183780 PTHR10806:SF6 SIGNAL PEPTIDASE COMPLEX CATALYTIC SUBUNIT SEC11 SIGNAL PEPTIDASE COMPLEX CATALYTIC SUBUNIT SEC11 serine protease#PC00203;protein modifying enzyme#PC00260 Endothelin signaling pathway#P00019>signal peptidase#P00573;Vasopressin synthesis#P04395>Signal Peptidase#P04589 CIOIN|Ensembl=ENSCING00000012000.2|UniProtKB=F6RWZ5 F6RWZ5 PTHR24410:SF48 HL07962P-RELATED BTB DOMAIN-CONTAINING PROTEIN defense/immunity protein#PC00090 CIOIN|Ensembl=ENSCING00000007208.3|UniProtKB=F6Y7N9 F6Y7N9 LOC100183669 PTHR47992:SF150 PROTEIN PHOSPHATASE PROTEIN PHOSPHATASE 1D hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;protein serine/threonine phosphatase activity#GO:0004722;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;dephosphorylation#GO:0016311;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein dephosphorylation#GO:0006470;cellular metabolic process#GO:0044237;cellular process#GO:0009987;protein metabolic process#GO:0019538;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 protein phosphatase#PC00195;protein modifying enzyme#PC00260 p53 pathway feedback loops 2#P04398>WIP-1#P04650;p53 pathway#P00059>WIP-1#G04693;p53 pathway feedback loops 2#P04398>WIP-1#G04708 CIOIN|Ensembl=ENSCING00000023995.1|UniProtKB=H2XVN4 H2XVN4 LOC100184165 PTHR12831:SF0 TRANSCRIPTION INITIATION FACTOR IIH TFIIH , POLYPEPTIDE 3-RELATED GENERAL TRANSCRIPTION FACTOR IIH SUBUNIT 3 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;nucleotide-excision repair#GO:0006289;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;DNA damage response#GO:0006974;response to stress#GO:0006950;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular response to stress#GO:0033554;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;DNA-directed RNA polymerase complex#GO:0000428;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;serine/threonine protein kinase complex#GO:1902554;RNA polymerase II transcription regulator complex#GO:0090575;protein kinase complex#GO:1902911;transcription factor TFIIH core complex#GO:0000439;intracellular protein-containing complex#GO:0140535;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695;RNA polymerase II, holoenzyme#GO:0016591;RNA polymerase complex#GO:0030880;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;transcription factor TFIIH holo complex#GO:0005675;nuclear protein-containing complex#GO:0140513 RNA metabolism protein#PC00031;general transcription factor#PC00259 Transcription regulation by bZIP transcription factor#P00055>TFIIH complex#P01392;General transcription regulation#P00023>TFIIH complex#P00664 CIOIN|Ensembl=ENSCING00000002326.3|UniProtKB=F6PJU1 F6PJU1 LOC100183184 PTHR13489:SF0 MINI-CHROMOSOME MAINTENANCE COMPLEX-BINDING PROTEIN MINI-CHROMOSOME MAINTENANCE COMPLEX-BINDING PROTEIN protein-containing complex binding#GO:0044877;binding#GO:0005488;chromatin binding#GO:0003682 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;DNA-templated DNA replication#GO:0006261;DNA replication#GO:0006260;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259;metabolic process#GO:0008152 CIOIN|Ensembl=ENSCING00000008615.3|UniProtKB=F6T2C1 F6T2C1 PTHR23050:SF530 CALCIUM BINDING PROTEIN CALMODULIN cation binding#GO:0043169;small molecule binding#GO:0036094;molecular function regulator activity#GO:0098772;binding#GO:0005488;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;enzyme regulator activity#GO:0030234 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 calmodulin-related#PC00061 CIOIN|Ensembl=ENSCING00000012788.2|UniProtKB=F6XCL4 F6XCL4 LOC100179352 PTHR21013:SF10 ATP SYNTHASE MITOCHONDRIAL F1 COMPLEX ASSEMBLY FACTOR 2/ATP12 PROTEIN, MITOCHONDRIAL PRECURSOR ATP SYNTHASE MITOCHONDRIAL F1 COMPLEX ASSEMBLY FACTOR 2 chaperone#PC00072 CIOIN|Ensembl=ENSCING00000012386.2|UniProtKB=F6YQV7 F6YQV7 LOC100179801 PTHR11709:SF518 MULTI-COPPER OXIDASE MULTICOPPER OXIDASE oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 oxidase#PC00175;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000000191.3|UniProtKB=F6WFF8 F6WFF8 PTHR12326:SF12 PLECKSTRIN HOMOLOGY DOMAIN CONTAINING PROTEIN PLECKSTRIN HOMOLOGY AND RUN DOMAIN CONTAINING M1 CIOIN|Ensembl=ENSCING00000014578.2|UniProtKB=F6UYP5 F6UYP5 PTHR34400:SF4 FAMILY NOT NAMED MEMBRANE PROTEIN CIOIN|Ensembl=ENSCING00000006244.3|UniProtKB=F6YBW7 F6YBW7 LOC100184010 PTHR10971:SF11 MRNA EXPORT FACTOR AND BUB3 MRNA EXPORT FACTOR RAE1 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;protein binding#GO:0005515;ubiquitin-like protein binding#GO:0032182;binding#GO:0005488;organic cyclic compound binding#GO:0097159;ubiquitin binding#GO:0043130 cellular localization#GO:0051641;macromolecule localization#GO:0033036;establishment of RNA localization#GO:0051236;transport#GO:0006810;nucleic acid transport#GO:0050657;nitrogen compound transport#GO:0071705;cellular component organization#GO:0016043;cellular process#GO:0009987;RNA localization#GO:0006403;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery#GO:0000972;nuclear export#GO:0051168;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;organelle organization#GO:0006996;chromosome organization#GO:0051276;RNA transport#GO:0050658;nucleobase-containing compound transport#GO:0015931;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;nuclear transport#GO:0051169 envelope#GO:0031975;nuclear pore#GO:0005643;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear envelope#GO:0005635;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;organelle envelope#GO:0031967;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000009100.3|UniProtKB=F6QDG1 F6QDG1 LOC100181112 PTHR19861:SF0 WD40 REPEAT PROTEIN SWD2 WD REPEAT-CONTAINING PROTEIN 82 protein-containing complex binding#GO:0044877;binding#GO:0005488;chromatin binding#GO:0003682 membrane-enclosed lumen#GO:0031974;histone methyltransferase complex#GO:0035097;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;methyltransferase complex#GO:0034708;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;Set1C/COMPASS complex#GO:0048188;nuclear protein-containing complex#GO:0140513 methyltransferase#PC00155;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000005675.3|UniProtKB=F6YXX9 F6YXX9 PTHR12442:SF5 DYNEIN INTERMEDIATE CHAIN DYNEIN AXONEMAL INTERMEDIATE CHAIN 3 protein binding#GO:0005515;binding#GO:0005488 cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cell projection organization#GO:0030030;inner dynein arm assembly#GO:0036159;microtubule-based movement#GO:0007018;microtubule cytoskeleton organization#GO:0000226;cilium or flagellum-dependent cell motility#GO:0001539;protein-containing complex assembly#GO:0065003;cell motility#GO:0048870;cellular component organization#GO:0016043;axoneme assembly#GO:0035082;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031;cilium movement involved in cell motility#GO:0060294;cilium movement#GO:0003341;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cilium-dependent cell motility#GO:0060285;microtubule-based process#GO:0007017;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;microtubule bundle formation#GO:0001578;axonemal dynein complex assembly#GO:0070286;cytoskeleton organization#GO:0007010;plasma membrane bounded cell projection assembly#GO:0120031 axoneme#GO:0005930;inner dynein arm#GO:0036156;catalytic complex#GO:1902494;cytoplasmic region#GO:0099568;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;microtubule associated complex#GO:0005875;axonemal dynein complex#GO:0005858;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;ciliary plasm#GO:0097014;plasma membrane bounded cell projection cytoplasm#GO:0032838;membrane-bounded organelle#GO:0043227;dynein complex#GO:0030286;cell projection#GO:0042995;cytoskeleton#GO:0005856;cilium#GO:0005929 microtubule or microtubule-binding cytoskeletal protein#PC00157 CIOIN|Ensembl=ENSCING00000017667.2|UniProtKB=F6X638 F6X638 PTHR20920:SF5 RPE-SPONDIN SMB DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000000864.3|UniProtKB=F6QVW6 F6QVW6 PTHR11265:SF0 S-ADENOSYL-METHYLTRANSFERASE MRAW 12S RRNA N4-METHYLCYTIDINE METHYLTRANSFERASE catalytic activity, acting on RNA#GO:0140098;N-methyltransferase activity#GO:0008170;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on a rRNA#GO:0140102;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;rRNA methyltransferase activity#GO:0008649;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;RNA methyltransferase activity#GO:0008173 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;RNA modification#GO:0009451;rRNA modification#GO:0000154;RNA processing#GO:0006396;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;ribosome biogenesis#GO:0042254;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;rRNA methylation#GO:0031167;nucleic acid metabolic process#GO:0090304;methylation#GO:0032259;macromolecule methylation#GO:0043414;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;rRNA base methylation#GO:0070475;RNA methylation#GO:0001510 methyltransferase#PC00155;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000000067.3|UniProtKB=F6V6F4 F6V6F4 PTHR45887:SF1 TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT EPSILON TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT EPSILON nucleoside-triphosphatase regulator activity#GO:0060589;nucleic acid binding#GO:0003676;translation initiation factor binding#GO:0031369;translation regulator activity#GO:0045182;GTPase regulator activity#GO:0030695;binding#GO:0005488;organic cyclic compound binding#GO:0097159;molecular function regulator activity#GO:0098772;translation initiation factor activity#GO:0003743;protein binding#GO:0005515;translation regulator activity, nucleic acid binding#GO:0090079;enzyme regulator activity#GO:0030234;translation factor activity, RNA binding#GO:0008135;guanyl-nucleotide exchange factor activity#GO:0005085 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622 translation initiation factor#PC00224;translation factor#PC00223;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000007259.3|UniProtKB=F6U7S8 F6U7S8 PTHR24412:SF498 KELCH PROTEIN KELCH-LIKE PROTEIN 26 ISOFORM X1 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000024718.1|UniProtKB=H2XY34 H2XY34 PTHR23003:SF51 RNA RECOGNITION MOTIF RRM DOMAIN CONTAINING PROTEIN SERINE-ARGININE PROTEIN 55 nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA splicing factor#PC00148;RNA processing factor#PC00147;RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000021159.1|UniProtKB=H2XLP1 H2XLP1 PTHR43675:SF8 ARSENITE METHYLTRANSFERASE ARSENITE METHYLTRANSFERASE methyltransferase activity#GO:0008168;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824 methyltransferase#PC00155;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000020052.1|UniProtKB=H2XV90 H2XV90 LOC100179235 PTHR20930:SF0 OVARIAN CARCINOMA ANTIGEN CA125-RELATED PROTEIN ILRUN CIOIN|Ensembl=ENSCING00000024383.1|UniProtKB=H2Y3S8 H2Y3S8 PTHR22870:SF155 REGULATOR OF CHROMOSOME CONDENSATION E3 UBIQUITIN-PROTEIN LIGASE HERC1-RELATED guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 CIOIN|Ensembl=ENSCING00000003133.3|UniProtKB=F6RBW8 F6RBW8 LOC100182315 PTHR18929:SF240 PROTEIN DISULFIDE ISOMERASE PROTEIN DISULFIDE-ISOMERASE isomerase activity#GO:0016853;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;protein disulfide isomerase activity#GO:0003756 cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;response to endoplasmic reticulum stress#GO:0034976;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;response to stress#GO:0006950;protein folding#GO:0006457;nitrogen compound metabolic process#GO:0006807;cellular response to stress#GO:0033554;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chaperone#PC00072 CIOIN|Ensembl=ENSCING00000005566.3|UniProtKB=F6URP5 F6URP5 PTHR24026:SF51 FAT ATYPICAL CADHERIN-RELATED PROTOCADHERIN-LIKE WING POLARITY PROTEIN STAN cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987 cell adhesion molecule#PC00069;cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 CIOIN|Ensembl=ENSCING00000014250.2|UniProtKB=F6XB39 F6XB39 LOC100176157 PTHR45788:SF4 SUCCINATE/FUMARATE MITOCHONDRIAL TRANSPORTER-RELATED TRICARBOXYLATE TRANSPORT PROTEIN, MITOCHONDRIAL secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;organic acid transmembrane transporter activity#GO:0005342;citrate transmembrane transporter activity#GO:0015137;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 localization#GO:0051179;mitochondrial transport#GO:0006839;organic substance transport#GO:0071702;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;organic anion transport#GO:0015711;organic acid transport#GO:0015849;transport#GO:0006810;carboxylic acid transport#GO:0046942;organic acid transmembrane transport#GO:1903825;cellular process#GO:0009987;mitochondrial transmembrane transport#GO:1990542;citrate transport#GO:0015746;tricarboxylic acid transport#GO:0006842;carboxylic acid transmembrane transport#GO:1905039 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transporter#PC00227 CIOIN|Ensembl=ENSCING00000002654.3|UniProtKB=F6YDG7 F6YDG7 PTHR18934:SF109 ATP-DEPENDENT RNA HELICASE ATP-DEPENDENT RNA HELICASE DHX15 HOMOLOG nucleic acid binding#GO:0003676;RNA binding#GO:0003723;helicase activity#GO:0004386;ATP-dependent activity#GO:0140657;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;catalytic activity, acting on a nucleic acid#GO:0140640 cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 RNA helicase#PC00032 CIOIN|Ensembl=ENSCING00000002798.3|UniProtKB=F6XMV6 F6XMV6 PTHR22909:SF24 GOLGI INTEGRAL MEMBRANE PROTEIN 4 GOLGI INTEGRAL MEMBRANE PROTEIN 4-RELATED cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000011509.2|UniProtKB=F6WUC3 F6WUC3 LOC100185530 PTHR44156:SF5 SUPERNUMERARY LIMBS, ISOFORM B-RELATED WD REPEAT-CONTAINING PROTEIN 55 CIOIN|Ensembl=ENSCING00000016042.2|UniProtKB=F6W6Z3 F6W6Z3 LOC100178781 PTHR10701:SF0 SMALL NUCLEAR RIBONUCLEOPROTEIN-ASSOCIATED PROTEIN B AND N SMALL NUCLEAR RIBONUCLEOPROTEIN-ASSOCIATED PROTEIN B ribonucleoprotein complex binding#GO:0043021;protein-containing complex binding#GO:0044877;binding#GO:0005488 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;mRNA splicing, via spliceosome#GO:0000398;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 catalytic step 2 spliceosome#GO:0071013;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;U4/U6 x U5 tri-snRNP complex#GO:0046540;U1 snRNP#GO:0005685;U2-type spliceosomal complex#GO:0005684;cellular anatomical entity#GO:0110165;organelle#GO:0043226;U4 snRNP#GO:0005687;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;U5 snRNP#GO:0005682;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;spliceosomal snRNP complex#GO:0097525;small nuclear ribonucleoprotein complex#GO:0030532;protein-containing complex#GO:0032991;U2 snRNP#GO:0005686;U2-type prespliceosome#GO:0071004;spliceosomal tri-snRNP complex#GO:0097526;membrane-bounded organelle#GO:0043227;Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513 RNA splicing factor#PC00148;RNA processing factor#PC00147;RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000005015.3|UniProtKB=F6TXJ2 F6TXJ2 ncam PTHR23277:SF108 NECTIN-RELATED FASCICLIN-3 cell-cell adhesion via plasma-membrane adhesion molecules#GO:0098742;heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules#GO:0007157;cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987;homophilic cell adhesion via plasma membrane adhesion molecules#GO:0007156 cell junction#GO:0030054;adherens junction#GO:0005912;cellular anatomical entity#GO:0110165;cell-cell junction#GO:0005911;anchoring junction#GO:0070161 cell adhesion molecule#PC00069 CIOIN|Ensembl=ENSCING00000021570.1|UniProtKB=H2XL64 H2XL64 PTHR19306:SF6 STRUCTURAL MAINTENANCE OF CHROMOSOMES 5,6 SMC5, SMC6 STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 6 damaged DNA binding#GO:0003684;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;single-stranded DNA binding#GO:0003697;DNA binding#GO:0003677 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;double-strand break repair via homologous recombination#GO:0000724;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;response to stress#GO:0006950;nitrogen compound metabolic process#GO:0006807;recombinational repair#GO:0000725;cellular response to stress#GO:0033554;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;site of DNA damage#GO:0090734;catalytic complex#GO:1902494;transferase complex#GO:1990234;condensed chromosome#GO:0000793;site of double-strand break#GO:0035861;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227 DNA metabolism protein#PC00009 CIOIN|Ensembl=ENSCING00000005800.3|UniProtKB=F6RHH3 F6RHH3 PTHR13803:SF39 SEC24-RELATED PROTEIN SECRETORY 24AB, ISOFORM A cation binding#GO:0043169;small molecule binding#GO:0036094;zinc ion binding#GO:0008270;binding#GO:0005488;transition metal ion binding#GO:0046914;metal ion binding#GO:0046872;protein binding#GO:0005515;ion binding#GO:0043167;SNARE binding#GO:0000149 endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;membrane organization#GO:0061024;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;COPII-coated vesicle budding#GO:0090114;establishment of localization in cell#GO:0051649;vesicle organization#GO:0016050;intracellular transport#GO:0046907 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;ER to Golgi transport vesicle membrane#GO:0012507;endoplasmic reticulum exit site#GO:0070971;COPII-coated ER to Golgi transport vesicle#GO:0030134;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;coated vesicle#GO:0030135;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;vesicle coat#GO:0030120;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;transport vesicle membrane#GO:0030658;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;membrane coat#GO:0030117;coated vesicle membrane#GO:0030662;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;transport vesicle#GO:0030133;coated membrane#GO:0048475;cytoplasmic vesicle membrane#GO:0030659;endoplasmic reticulum#GO:0005783 vesicle coat protein#PC00235 CIOIN|Ensembl=ENSCING00000007712.3|UniProtKB=F7A2F3 F7A2F3 PTHR34924:SF1 UPF0573 PROTEIN C2ORF70 PROTEIN FAM166C CIOIN|Ensembl=ENSCING00000019032.1|UniProtKB=H2XZ38 H2XZ38 LOC100182886 PTHR14742:SF0 RIBONUCLEASE P SUBUNIT P21 RIBONUCLEASE P PROTEIN SUBUNIT P21 endoribonuclease#PC00094;RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000013857.1|UniProtKB=F6QGJ1 F6QGJ1 PTHR22750:SF47 G-PROTEIN COUPLED RECEPTOR CANNABINOID RECEPTOR 1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052;regulation of metabolic process#GO:0019222 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Endogenous cannabinoid signaling#P05730>CB1#P05743 CIOIN|Ensembl=ENSCING00000022335.1|UniProtKB=F7B503 F7B503 LOC100183401 PTHR12087:SF0 ORIGIN RECOGNITION COMPLEX SUBUNIT 4 ORIGIN RECOGNITION COMPLEX SUBUNIT 4 sequence-specific double-stranded DNA binding#GO:1990837;DNA replication origin binding#GO:0003688;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;DNA-templated DNA replication#GO:0006261;DNA replication#GO:0006260;DNA replication initiation#GO:0006270;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 origin recognition complex#GO:0000808;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;nuclear origin of replication recognition complex#GO:0005664;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 DNA metabolism protein#PC00009;replication origin binding protein#PC00199 CIOIN|Ensembl=ENSCING00000021529.1|UniProtKB=H2XYK8 H2XYK8 PTHR14744:SF15 N-ALPHA-ACETYLTRANSFERASE 60 N-ALPHA-ACETYLTRANSFERASE 60 histone modifying activity#GO:0140993;histone acetyltransferase activity#GO:0004402;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;N-acetyltransferase activity#GO:0008080;acetyltransferase activity#GO:0016407;peptide-lysine-N-acetyltransferase activity#GO:0061733;peptide N-acetyltransferase activity#GO:0034212;catalytic activity#GO:0003824;peptide alpha-N-acetyltransferase activity#GO:0004596;catalytic activity, acting on a protein#GO:0140096;N-acyltransferase activity#GO:0016410 macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;protein acylation#GO:0043543;cellular process#GO:0009987;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;protein acetylation#GO:0006473;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 bounding membrane of organelle#GO:0098588;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;Golgi membrane#GO:0000139;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 acetyltransferase#PC00038 CIOIN|Ensembl=ENSCING00000005267.3|UniProtKB=F6V9C5 F6V9C5 tbx20 PTHR11267:SF190 T-BOX PROTEIN-RELATED T-BOX TRANSCRIPTION FACTOR TBX20 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cell fate commitment#GO:0045165;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;cell fate specification#GO:0001708;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;Rel homology transcription factor#PC00252;immunoglobulin fold transcription factor#PC00251 CIOIN|Ensembl=ENSCING00000024288.1|UniProtKB=H2XNA4 H2XNA4 PTHR42861:SF127 CALCIUM-TRANSPORTING ATPASE CALCIUM-TRANSPORTING ATPASE SARCOPLASMIC_ENDOPLASMIC RETICULUM TYPE calcium ion transmembrane transporter activity#GO:0015085;inorganic molecular entity transmembrane transporter activity#GO:0015318;transmembrane transporter activity#GO:0022857;primary active transmembrane transporter activity#GO:0015399;ATP-dependent activity#GO:0140657;metal ion transmembrane transporter activity#GO:0046873;active monoatomic ion transmembrane transporter activity#GO:0022853;P-type ion transporter activity#GO:0015662;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;ATPase-coupled transmembrane transporter activity#GO:0042626;monoatomic cation transmembrane transporter activity#GO:0008324;monoatomic ion transmembrane transporter activity#GO:0015075;inorganic cation transmembrane transporter activity#GO:0022890;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;calcium ion transmembrane transport#GO:0070588;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;homeostatic process#GO:0042592;monoatomic cation homeostasis#GO:0055080;inorganic ion transmembrane transport#GO:0098660;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;cellular process#GO:0009987;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;calcium ion transport#GO:0006816;monoatomic ion homeostasis#GO:0050801;localization#GO:0051179;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation transport#GO:0006812;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655 cellular anatomical entity#GO:0110165;membrane#GO:0016020 primary active transporter#PC00068;transporter#PC00227 CIOIN|Ensembl=ENSCING00000022268.1|UniProtKB=H2XSB5 H2XSB5 LOC100179837 PTHR12406:SF41 CALCIUM-INDEPENDENT PHOSPHOLIPASE A2 IPLA2 -RELATED BRUMMER, ISOFORM B-RELATED hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;catalytic activity#GO:0003824;triglyceride lipase activity#GO:0004806 lipid metabolic process#GO:0006629;triglyceride metabolic process#GO:0006641;neutral lipid catabolic process#GO:0046461;cellular metabolic process#GO:0044237;homeostatic process#GO:0042592;glycerolipid catabolic process#GO:0046503;lipid catabolic process#GO:0016042;triglyceride catabolic process#GO:0019433;chemical homeostasis#GO:0048878;cellular process#GO:0009987;acylglycerol metabolic process#GO:0006639;primary metabolic process#GO:0044238;acylglycerol catabolic process#GO:0046464;neutral lipid metabolic process#GO:0006638;glycerolipid metabolic process#GO:0046486;lipid homeostasis#GO:0055088;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;cellular lipid metabolic process#GO:0044255;cellular lipid catabolic process#GO:0044242;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;lipid droplet#GO:0005811;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 phospholipase#PC00186 CIOIN|Ensembl=ENSCING00000006580.3|UniProtKB=F6R107 F6R107 LOC100187100 PTHR10742:SF386 FLAVIN MONOAMINE OXIDASE LYSINE-SPECIFIC HISTONE DEMETHYLASE 1A oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 oxidase#PC00175;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000010006.3|UniProtKB=F6QM57 F6QM57 PTHR15944:SF0 FARNESYLCYSTEINE LYASE PRENYLCYSTEINE LYASE DOMAIN-CONTAINING PROTEIN oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;primary metabolic process#GO:0044238;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 lyase#PC00144 CIOIN|Ensembl=ENSCING00000000574.3|UniProtKB=H2Y079 H2Y079 LOC100176680 PTHR10157:SF29 DOPAMINE BETA HYDROXYLASE RELATED DOPAMINE BETA-HYDROXYLASE cation binding#GO:0043169;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;transition metal ion binding#GO:0046914;copper ion binding#GO:0005507;metal ion binding#GO:0046872;ion binding#GO:0043167;oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497 organic hydroxy compound metabolic process#GO:1901615;cellular aromatic compound metabolic process#GO:0006725;amine metabolic process#GO:0009308;alcohol biosynthetic process#GO:0046165;biogenic amine metabolic process#GO:0006576;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;alcohol metabolic process#GO:0006066;organic hydroxy compound biosynthetic process#GO:1901617;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;catecholamine metabolic process#GO:0006584;biosynthetic process#GO:0009058;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;organic cyclic compound metabolic process#GO:1901360;aromatic compound catabolic process#GO:0019439;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;organic cyclic compound catabolic process#GO:1901361;catabolic process#GO:0009056;aromatic compound biosynthetic process#GO:0019438;small molecule biosynthetic process#GO:0044283;organic substance catabolic process#GO:1901575;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152 bounding membrane of organelle#GO:0098588;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;secretory granule membrane#GO:0030667;extracellular region#GO:0005576;secretory granule#GO:0030141;organelle membrane#GO:0031090;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;vesicle membrane#GO:0012506;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cytoplasmic vesicle membrane#GO:0030659;secretory vesicle#GO:0099503 hydroxylase#PC00122 Adrenaline and noradrenaline biosynthesis#P00001>DBH#P00063;Dopamine receptor mediated signaling pathway#P05912>DBH#P05955 CIOIN|Ensembl=ENSCING00000002214.3|UniProtKB=F6ZPX3 F6ZPX3 LOC100178591 PTHR45655:SF6 GUANYLATE CYCLASE SOLUBLE SUBUNIT BETA-2 HEAD-SPECIFIC GUANYLATE CYCLASE lyase activity#GO:0016829;cyclase activity#GO:0009975;phosphorus-oxygen lyase activity#GO:0016849;catalytic activity#GO:0003824 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;response to abiotic stimulus#GO:0009628;intracellular signaling cassette#GO:0141124;cGMP-mediated signaling#GO:0019934;cellular process#GO:0009987;signaling#GO:0023052;response to oxygen levels#GO:0070482;cyclic-nucleotide-mediated signaling#GO:0019935 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622 guanylate cyclase#PC00114 CIOIN|Ensembl=ENSCING00000017952.1|UniProtKB=H2XQR2 H2XQR2 PTHR47385:SF18 CALPONIN CALPONIN cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000005877.3|UniProtKB=F6T5R3 F6T5R3 PTHR11949:SF53 INTERFERON REGULATORY FACTOR IRF TRYPTOPHAN PENTAD REPEAT DOMAIN-CONTAINING PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 CIOIN|Ensembl=ENSCING00000007043.3|UniProtKB=F6ZCE0 F6ZCE0 PTHR48015:SF35 SERINE/THREONINE-PROTEIN KINASE TAO SERINE_THREONINE-PROTEIN KINASE PAK transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of MAPK cascade#GO:0043408;signal transduction#GO:0007165;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;regulation of signaling#GO:0023051;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular process#GO:0009987;regulation of intracellular signal transduction#GO:1902531;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PAK#P00837;Cytoskeletal regulation by Rho GTPase#P00016>PAK#P00517;Angiogenesis#P00005>PAK#P00249 CIOIN|Ensembl=ENSCING00000001618.3|UniProtKB=F6RYX9 F6RYX9 PTHR15665:SF1 ASTEROID PROTEIN PROTEIN ASTEROID HOMOLOG 1 CIOIN|Ensembl=ENSCING00000023927.1|UniProtKB=F6WAB5 F6WAB5 LOC100182325 PTHR10333:SF89 INHIBITOR OF GROWTH PROTEIN INHIBITOR OF GROWTH PROTEIN protein binding#GO:0005515;methylated histone binding#GO:0035064;histone binding#GO:0042393;binding#GO:0005488;modification-dependent protein binding#GO:0140030 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of RNA biosynthetic process#GO:2001141;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of RNA metabolic process#GO:0051254;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 CIOIN|Ensembl=ENSCING00000012865.2|UniProtKB=F6PZV6 F6PZV6 PTHR12496:SF2 CGI-41 METHYLTRANSFERASE METHYLTRANSFERASE-LIKE PROTEIN 25B RNA metabolism protein#PC00031;RNA methyltransferase#PC00033 CIOIN|Ensembl=ENSCING00000000760.3|UniProtKB=F6PW14 F6PW14 PTHR11461:SF211 SERINE PROTEASE INHIBITOR, SERPIN GH10112P-RELATED protease inhibitor#PC00191 CIOIN|Ensembl=ENSCING00000021740.1|UniProtKB=H2XSH5 H2XSH5 PTHR10924:SF4 MAJOR FACILITATOR SUPERFAMILY PROTEIN-RELATED GH15861P tetrapyrrole binding#GO:0046906;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;binding#GO:0005488;organic cyclic compound binding#GO:0097159;heme binding#GO:0020037 localization#GO:0051179;organic substance transport#GO:0071702;metal ion transport#GO:0030001;establishment of localization#GO:0051234;transport#GO:0006810;monoatomic cation transport#GO:0006812;nitrogen compound transport#GO:0071705;iron ion transport#GO:0006826;transition metal ion transport#GO:0000041;monoatomic ion transport#GO:0006811 cellular anatomical entity#GO:0110165;membrane#GO:0016020 secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000000955.3|UniProtKB=F7BAT7 F7BAT7 PTHR23222:SF0 PROHIBITIN PROHIBITIN 1 CIOIN|Ensembl=ENSCING00000002918.3|UniProtKB=F7BJW8 F7BJW8 PTHR45617:SF170 LEUCINE RICH REPEAT FAMILY PROTEIN MIP14966P scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000013447.2|UniProtKB=F6V2M0 F6V2M0 LOC100180839 PTHR10151:SF120 ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE BIS(5'-ADENOSYL)-TRIPHOSPHATASE metabolite interconversion enzyme#PC00262;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000006391.3|UniProtKB=F6X6Z3 F6X6Z3 LOC100181743 PTHR24012:SF796 RNA BINDING PROTEIN PROTEIN ALAN SHEPARD nucleic acid binding#GO:0003676;single-stranded RNA binding#GO:0003727;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159;mRNA binding#GO:0003729;poly(A) binding#GO:0008143;mRNA 3'-UTR binding#GO:0003730 cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000001401.3|UniProtKB=F6ZB26 F6ZB26 LOC100184311 PTHR46212:SF3 PEFLIN GH27120P CIOIN|Ensembl=ENSCING00000011339.2|UniProtKB=F6UXP7 F6UXP7 LOC100181722 PTHR13015:SF0 PROTEIN AD-016-RELATED WASH COMPLEX SUBUNIT 3 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;transport#GO:0006810;protein-containing complex assembly#GO:0065003;vesicle-mediated transport#GO:0016192;actin polymerization or depolymerization#GO:0008154;actin filament polymerization#GO:0030041;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;exocytosis#GO:0006887;establishment of localization#GO:0051234;secretion#GO:0046903;protein-containing complex organization#GO:0043933;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;protein polymerization#GO:0051258;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;export from cell#GO:0140352;secretion by cell#GO:0032940 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000016990.2|UniProtKB=F7A141 F7A141 PTHR24418:SF460 TYROSINE-PROTEIN KINASE PROTEIN KINASE DOMAIN-CONTAINING PROTEIN protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;non-membrane spanning protein tyrosine kinase activity#GO:0004715;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 non-receptor tyrosine protein kinase#PC00168 CIOIN|Ensembl=ENSCING00000021058.1|UniProtKB=H2XLJ4 H2XLJ4 LOC100181990 PTHR43161:SF23 SORBITOL DEHYDROGENASE (R,R)-BUTANEDIOL DEHYDROGENASE-RELATED dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000001571.3|UniProtKB=F6VZA9 F6VZA9 LOC100181052 PTHR12736:SF7 LANC-LIKE PROTEIN LANC-LIKE PROTEIN 3 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 CIOIN|Ensembl=ENSCING00000003296.3|UniProtKB=F6WMR5 F6WMR5 LOC100175116 PTHR24074:SF56 CO-CHAPERONE PROTEIN DJLA LD30543P chaperone#PC00072 CIOIN|Ensembl=ENSCING00000019523.1|UniProtKB=H2Y0H7 H2Y0H7 LOC100178514 PTHR20996:SF1 NUCLEAR ENVELOPE PHOSPHATASE-REGULATORY SUBUNIT 1 NUCLEAR ENVELOPE PHOSPHATASE-REGULATORY SUBUNIT 1 cytoplasm#GO:0005737;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;catalytic complex#GO:1902494;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;protein serine/threonine phosphatase complex#GO:0008287;cellular anatomical entity#GO:0110165;membrane#GO:0016020;intracellular anatomical structure#GO:0005622 phosphatase modulator#PC00184 CIOIN|Ensembl=ENSCING00000005168.3|UniProtKB=F6PZR6 F6PZR6 PTHR15605:SF2 KINESIN-ASSOCIATED PROTEINS KINESIN-ASSOCIATED PROTEIN 3 cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782;cell projection organization#GO:0030030;microtubule-based process#GO:0007017;organelle organization#GO:0006996;microtubule-based movement#GO:0007018;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036 axoneme#GO:0005930;cytoplasmic region#GO:0099568;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;ciliary transition zone#GO:0035869;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;microtubule associated complex#GO:0005875;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;ciliary plasm#GO:0097014;plasma membrane bounded cell projection cytoplasm#GO:0032838;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;cell projection#GO:0042995;cilium#GO:0005929 cytoskeletal protein#PC00085;microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 CIOIN|Ensembl=ENSCING00000023015.1|UniProtKB=H2XVZ6 H2XVZ6 PTHR31399:SF0 DNA-DIRECTED PRIMASE / POLYMERASE PROTEIN DNA-DIRECTED PRIMASE_POLYMERASE PROTEIN catalytic activity, acting on RNA#GO:0140098;DNA-directed DNA polymerase activity#GO:0003887;5'-3' RNA polymerase activity#GO:0034062;transferase activity#GO:0016740;DNA-directed 5'-3' RNA polymerase activity#GO:0003899;chromatin binding#GO:0003682;binding#GO:0005488;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a nucleic acid#GO:0140640;RNA polymerase activity#GO:0097747;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on DNA#GO:0140097;protein-containing complex binding#GO:0044877;DNA polymerase activity#GO:0034061 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;response to radiation#GO:0009314;cellular nitrogen compound biosynthetic process#GO:0044271;DNA-templated DNA replication#GO:0006261;mitochondrion organization#GO:0007005;replication fork processing#GO:0031297;response to abiotic stimulus#GO:0009628;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;mitochondrial genome maintenance#GO:0000002;response to light stimulus#GO:0009416;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;postreplication repair#GO:0006301;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular component organization#GO:0016043;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;translesion synthesis#GO:0019985;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;response to stress#GO:0006950;mitochondrial DNA metabolic process#GO:0032042;organelle organization#GO:0006996;response to UV#GO:0009411;DNA biosynthetic process#GO:0071897;DNA synthesis involved in DNA repair#GO:0000731;aromatic compound biosynthetic process#GO:0019438;cellular response to stress#GO:0033554;DNA replication#GO:0006260;DNA metabolic process#GO:0006259 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA metabolism protein#PC00009 CIOIN|Ensembl=ENSCING00000000654.3|UniProtKB=F6RJQ4 F6RJQ4 PTHR11530:SF15 D-AMINO ACID OXIDASE D-AMINO-ACID OXIDASE catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 oxoacid metabolic process#GO:0043436;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;amino acid catabolic process#GO:0009063;small molecule catabolic process#GO:0044282;nitrogen compound metabolic process#GO:0006807;alpha-amino acid metabolic process#GO:1901605;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;carboxylic acid metabolic process#GO:0019752;amino acid metabolic process#GO:0006520;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 oxidase#PC00175;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000018485.1|UniProtKB=H2XM24 H2XM24 PTHR19143:SF458 FIBRINOGEN/TENASCIN/ANGIOPOEITIN FIBRINOGEN C-TERMINAL DOMAIN-CONTAINING PROTEIN-RELATED external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 CIOIN|Ensembl=ENSCING00000021992.1|UniProtKB=H2XYC1 H2XYC1 PTHR19143:SF459 FIBRINOGEN/TENASCIN/ANGIOPOEITIN FIBRINOGEN C-TERMINAL DOMAIN-CONTAINING PROTEIN external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 CIOIN|Ensembl=ENSCING00000024140.1|UniProtKB=H2XW46 H2XW46 PTHR19308:SF53 PHOSPHATIDYLCHOLINE TRANSFER PROTEIN CERAMIDE TRANSFER PROTEIN amide transport#GO:0042886;localization#GO:0051179;organic substance transport#GO:0071702;cellular localization#GO:0051641;establishment of localization#GO:0051234;macromolecule localization#GO:0033036;transport#GO:0006810;nitrogen compound transport#GO:0071705;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;lipid localization#GO:0010876;cellular process#GO:0009987;lipid transport#GO:0006869;intracellular lipid transport#GO:0032365 CIOIN|Ensembl=ENSCING00000024299.1|UniProtKB=F6T614 F6T614 LOC100185967 PTHR22802:SF396 C-TYPE LECTIN SUPERFAMILY MEMBER C-TYPE LECTIN DOMAIN-CONTAINING PROTEIN membrane traffic protein#PC00150 CIOIN|Ensembl=ENSCING00000002776.3|UniProtKB=F6ZZ26 F6ZZ26 PTHR10825:SF29 RING FINGER DOMAIN-CONTAINING, POLYCOMB GROUP COMPONENT POLYCOMB GROUP RING FINGER PROTEIN 1 chromatin/chromatin-binding, or -regulatory protein#PC00077;histone modifying enzyme#PC00261 CIOIN|Ensembl=ENSCING00000008322.1|UniProtKB=F6Q7E0 F6Q7E0 LOC100184513 PTHR10671:SF96 EPITHELIAL MEMBRANE PROTEIN-RELATED CLC-LIKE PROTEIN 5 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cytoskeletal protein#PC00085 CIOIN|Ensembl=ENSCING00000023646.1|UniProtKB=H2XU51 H2XU51 LOC100180046 PTHR45445:SF2 FAMILY NOT NAMED METHYLTRANSFERASE TYPE 11 DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000019826.1|UniProtKB=H2XJL4 H2XJL4 PTHR45710:SF26 C-TYPE LECTIN DOMAIN-CONTAINING PROTEIN 180 RH26557P defense/immunity protein#PC00090 CIOIN|Ensembl=ENSCING00000021306.1|UniProtKB=H2XT76 H2XT76 PTHR46901:SF2 GH04942P GH04942P CIOIN|Ensembl=ENSCING00000012910.2|UniProtKB=F6RN60 F6RN60 PTHR10803:SF3 ARSENICAL PUMP-DRIVING ATPASE ARSENITE-TRANSLOCATING ATPASE ATPASE GET3 pyrophosphatase activity#GO:0016462;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;ATP hydrolysis activity#GO:0016887 transporter#PC00227 CIOIN|Ensembl=ENSCING00000011860.2|UniProtKB=F6Z2L4 F6Z2L4 LOC100179674 PTHR13678:SF27 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 37 LD45836P cellular localization#GO:0051641;macromolecule localization#GO:0033036;protein targeting to vacuole#GO:0006623;transport#GO:0006810;protein catabolic process#GO:0030163;nitrogen compound transport#GO:0071705;organonitrogen compound catabolic process#GO:1901565;establishment of protein localization#GO:0045184;ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043162;modification-dependent macromolecule catabolic process#GO:0043632;organic substance transport#GO:0071702;establishment of protein localization to membrane#GO:0090150;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;protein localization to organelle#GO:0033365;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;localization within membrane#GO:0051668;macromolecule catabolic process#GO:0009057;establishment of protein localization to vacuole#GO:0072666;modification-dependent protein catabolic process#GO:0019941;vacuolar transport#GO:0007034;macromolecule metabolic process#GO:0043170;protein localization to membrane#GO:0072657;protein localization to vacuole#GO:0072665;protein targeting#GO:0006605;organonitrogen compound metabolic process#GO:1901564;establishment of protein localization to organelle#GO:0072594;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein localization#GO:0008104;ubiquitin-dependent protein catabolic process#GO:0006511;localization#GO:0051179;protein targeting to membrane#GO:0006612;cellular macromolecule localization#GO:0070727;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;endosome#GO:0005768;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endosome membrane#GO:0010008;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;ESCRT I complex#GO:0000813;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cytoplasmic vesicle membrane#GO:0030659 membrane trafficking regulatory protein#PC00151 CIOIN|Ensembl=ENSCING00000023158.1|UniProtKB=H2XK15 H2XK15 PTHR31784:SF2 BIOGENESIS OF LYSOSOME-RELATED ORGANELLES COMPLEX 1 SUBUNIT 5 BIOGENESIS OF LYSOSOME-RELATED ORGANELLES COMPLEX 1 SUBUNIT 5 intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991 CIOIN|Ensembl=ENSCING00000000848.3|UniProtKB=F6SCP4 F6SCP4 PTHR11937:SF545 ACTIN ACTIN, CYTOSKELETAL 3B actin and actin related protein#PC00039;cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 Alzheimer disease-presenilin pathway#P00004>actin#P00114;Nicotinic acetylcholine receptor signaling pathway#P00044>Actin#P01090;Huntington disease#P00029>Actin#P00807;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>F-actin#P00858;Cadherin signaling pathway#P00012>F-actin#P00470;Cytoskeletal regulation by Rho GTPase#P00016>Actin#P00512 CIOIN|Ensembl=ENSCING00000022062.1|UniProtKB=H2XZC9 H2XZC9 PTHR42858:SF1 AMINOTRANSFERASE LD15494P transaminase activity#GO:0008483;transferase activity#GO:0016740;catalytic activity#GO:0003824 transaminase#PC00216;transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000022368.1|UniProtKB=H2XYK0 H2XYK0 PTHR21396:SF2 39S RIBOSOMAL PROTEIN L43 LARGE RIBOSOMAL SUBUNIT PROTEIN ML43 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;mitochondrial large ribosomal subunit#GO:0005762;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;mitochondrial ribosome#GO:0005761;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;ribosomal subunit#GO:0044391;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;organellar ribosome#GO:0000313;protein-containing complex#GO:0032991;large ribosomal subunit#GO:0015934;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;ribosome#GO:0005840;mitochondrial protein-containing complex#GO:0098798 ribosomal protein#PC00202;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000004420.3|UniProtKB=A0A1W3JM62 A0A1W3JM62 LOC100183933 PTHR10634:SF149 AN1-TYPE ZINC FINGER PROTEIN AN1-TYPE DOMAIN-CONTAINING PROTEIN-RELATED CIOIN|Ensembl=ENSCING00000022175.1|UniProtKB=H2XYY3 H2XYY3 PTHR24299:SF21 CYTOCHROME P450 FAMILY 1 OS09G0441600 PROTEIN oxygenase#PC00177;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000019714.1|UniProtKB=H2XK95 H2XK95 LOC100177882 PTHR13031:SF0 RIBONUCLEASE P SUBUNIT P30 RIBONUCLEASE P PROTEIN SUBUNIT P30 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 endoribonuclease#PC00094;RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000005351.3|UniProtKB=F7ALN9 F7ALN9 LOC100187479 PTHR24412:SF172 KELCH PROTEIN KELCH-LIKE PROTEIN 10 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000022863.1|UniProtKB=H2XSA6 H2XSA6 PTHR11640:SF164 NEPHRIN MAM DOMAIN-CONTAINING GLYCOSYLPHOSPHATIDYLINOSITOL ANCHOR PROTEIN 1 cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;binding#GO:0005488 cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987 cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;plasma membrane#GO:0005886 immunoglobulin superfamily cell adhesion molecule#PC00125;cell adhesion molecule#PC00069 CIOIN|Ensembl=ENSCING00000007594.3|UniProtKB=F6ZKU9 F6ZKU9 LOC100183004 PTHR46458:SF1 BLR2807 PROTEIN GEO09476P1 transporter#PC00227 CIOIN|Ensembl=ENSCING00000023008.1|UniProtKB=F6X211 F6X211 LOC100180619 PTHR42861:SF127 CALCIUM-TRANSPORTING ATPASE CALCIUM-TRANSPORTING ATPASE SARCOPLASMIC_ENDOPLASMIC RETICULUM TYPE calcium ion transmembrane transporter activity#GO:0015085;inorganic molecular entity transmembrane transporter activity#GO:0015318;transmembrane transporter activity#GO:0022857;primary active transmembrane transporter activity#GO:0015399;ATP-dependent activity#GO:0140657;metal ion transmembrane transporter activity#GO:0046873;active monoatomic ion transmembrane transporter activity#GO:0022853;P-type ion transporter activity#GO:0015662;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;ATPase-coupled transmembrane transporter activity#GO:0042626;monoatomic cation transmembrane transporter activity#GO:0008324;monoatomic ion transmembrane transporter activity#GO:0015075;inorganic cation transmembrane transporter activity#GO:0022890;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;calcium ion transmembrane transport#GO:0070588;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;homeostatic process#GO:0042592;monoatomic cation homeostasis#GO:0055080;inorganic ion transmembrane transport#GO:0098660;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;cellular process#GO:0009987;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;calcium ion transport#GO:0006816;monoatomic ion homeostasis#GO:0050801;localization#GO:0051179;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation transport#GO:0006812;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655 cellular anatomical entity#GO:0110165;membrane#GO:0016020 primary active transporter#PC00068;transporter#PC00227 CIOIN|Ensembl=ENSCING00000006721.3|UniProtKB=F7A7F8 F7A7F8 PTHR24211:SF20 LIM DOMAIN-CONTAINING PROTEIN PROTEIN ESPINAS-RELATED scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000020364.1|UniProtKB=H2XR04 H2XR04 PTHR46138:SF1 PROTEIN DR1 PROTEIN DR1 protein binding#GO:0005515;transcription factor binding#GO:0008134;binding#GO:0005488;TBP-class protein binding#GO:0017025 cellular aromatic compound metabolic process#GO:0006725;DNA-templated transcription#GO:0006351;cellular component biogenesis#GO:0044085;protein-DNA complex organization#GO:0071824;RNA metabolic process#GO:0016070;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;protein-DNA complex assembly#GO:0065004;RNA polymerase II preinitiation complex assembly#GO:0051123;nucleobase-containing compound metabolic process#GO:0006139;transcription initiation at RNA polymerase II promoter#GO:0006367;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;DNA-templated transcription initiation#GO:0006352;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular component organization#GO:0016043;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;protein-containing complex organization#GO:0043933;aromatic compound biosynthetic process#GO:0019438;transcription by RNA polymerase II#GO:0006366 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000012841.2|UniProtKB=F6W318 F6W318 LOC100180498 PTHR45919:SF1 GDP-MAN:MAN(3)GLCNAC(2)-PP-DOL ALPHA-1,2-MANNOSYLTRANSFERASE GDP-MAN:MAN(3)GLCNAC(2)-PP-DOL ALPHA-1,2-MANNOSYLTRANSFERASE mannosyltransferase activity#GO:0000030;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein N-linked glycosylation#GO:0006487;cellular lipid metabolic process#GO:0044255;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 cellular anatomical entity#GO:0110165;membrane#GO:0016020 transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000005525.3|UniProtKB=F6Y4K6 F6Y4K6 PTHR45630:SF7 CATION-TRANSPORTING ATPASE-RELATED ENDOPLASMIC RETICULUM TRANSMEMBRANE HELIX TRANSLOCASE transmembrane transporter activity#GO:0022857;primary active transmembrane transporter activity#GO:0015399;ATP-dependent activity#GO:0140657;active monoatomic ion transmembrane transporter activity#GO:0022853;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;P-type ion transporter activity#GO:0015662;ATPase-coupled transmembrane transporter activity#GO:0042626;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804;monoatomic ion transmembrane transporter activity#GO:0015075 inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;transmembrane transport#GO:0055085;transport#GO:0006810;homeostatic process#GO:0042592;monoatomic cation homeostasis#GO:0055080;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;cellular process#GO:0009987;chemical homeostasis#GO:0048878;intracellular calcium ion homeostasis#GO:0006874;monoatomic ion homeostasis#GO:0050801;localization#GO:0051179;establishment of localization#GO:0051234;intracellular monoatomic cation homeostasis#GO:0030003;intracellular monoatomic ion homeostasis#GO:0006873 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 primary active transporter#PC00068;transporter#PC00227 CIOIN|Ensembl=ENSCING00000004248.3|UniProtKB=F6YFZ5 F6YFZ5 PTHR45897:SF4 HIGH-AFFINITY CHOLINE TRANSPORTER 1 HIGH-AFFINITY CHOLINE TRANSPORTER 1 inorganic molecular entity transmembrane transporter activity#GO:0015318;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;sodium ion transmembrane transporter activity#GO:0015081;organic cation transmembrane transporter activity#GO:0015101;metal ion transmembrane transporter activity#GO:0046873;active monoatomic ion transmembrane transporter activity#GO:0022853;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;inorganic cation transmembrane transporter activity#GO:0022890;active transmembrane transporter activity#GO:0022804;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transporter#PC00227 Nicotinic acetylcholine receptor signaling pathway#P00044>CHT1#P01098;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>CHT1#P01084;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>CHT1#P01072 CIOIN|Ensembl=ENSCING00000012334.2|UniProtKB=F7ABL1 F7ABL1 PTHR10811:SF110 FRINGE-RELATED BETA-1,3-GLUCOSYLTRANSFERASE acetylglucosaminyltransferase activity#GO:0008375;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194;hexosyltransferase activity#GO:0016758 glycosyltransferase#PC00111;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000023848.1|UniProtKB=Q1RPX5 Q1RPX5 Ci-ZF(C3H)-14 PTHR12547:SF174 CCCH ZINC FINGER/TIS11-RELATED MRNA DECAY ACTIVATOR PROTEIN ZFP36L2 RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000024760.1|UniProtKB=H2XU77 H2XU77 PTHR19325:SF574 COMPLEMENT COMPONENT-RELATED SUSHI DOMAIN-CONTAINING SUSHI, VON WILLEBRAND FACTOR TYPE A, EGF AND PENTRAXIN DOMAIN-CONTAINING PROTEIN 1 complement component#PC00078 CIOIN|Ensembl=ENSCING00000009770.3|UniProtKB=Q1RL29 Q1RL29 Ci-ZF(PARP)-3 PTHR10459:SF112 DNA LIGASE POLY [ADP-RIBOSE] POLYMERASE 1 transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;glycosyltransferase activity#GO:0016757;pentosyltransferase activity#GO:0016763;catalytic activity#GO:0003824 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;double-strand break repair#GO:0006302;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;post-translational protein modification#GO:0043687;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;response to stress#GO:0006950;nitrogen compound metabolic process#GO:0006807;cellular response to stress#GO:0033554;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259;metabolic process#GO:0008152 intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA metabolism protein#PC00009 FAS signaling pathway#P00020>PARP#P00600 CIOIN|Ensembl=ENSCING00000006917.3|UniProtKB=F6WAM1 F6WAM1 LOC100183152 PTHR45011:SF1 DAP3-BINDING CELL DEATH ENHANCER 1 DAP3-BINDING CELL DEATH ENHANCER 1 CIOIN|Ensembl=ENSCING00000002321.2|UniProtKB=F6PP61 F6PP61 PTHR11599:SF5 PROTEASOME SUBUNIT ALPHA/BETA PROTEASOME SUBUNIT BETA TYPE-4 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;peptidase complex#GO:1905368;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;proteasome complex#GO:0000502;membrane-bounded organelle#GO:0043227;endopeptidase complex#GO:1905369;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protease#PC00190;protein modifying enzyme#PC00260 Parkinson disease#P00049>20S proteasome#P01227 CIOIN|Ensembl=ENSCING00000006401.3|UniProtKB=F6QSK8 F6QSK8 LOC100177545 PTHR19980:SF0 RNA CLEAVAGE STIMULATION FACTOR CLEAVAGE STIMULATION FACTOR SUBUNIT 3 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 mRNA polyadenylation factor#PC00146;RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000013325.2|UniProtKB=F6ZFT6 F6ZFT6 PTHR22761:SF5 CHARGED MULTIVESICULAR BODY PROTEIN CHARGED MULTIVESICULAR BODY PROTEIN 6 endosomal transport#GO:0016197;cellular localization#GO:0051641;membrane organization#GO:0061024;vacuolar transport#GO:0007034;transport#GO:0006810;late endosome to vacuole transport via multivesicular body sorting pathway#GO:0032511;vesicle-mediated transport#GO:0016192;late endosome to vacuole transport#GO:0045324;cellular component organization#GO:0016043;cellular process#GO:0009987;multivesicular body sorting pathway#GO:0071985;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;vesicle budding from membrane#GO:0006900;establishment of localization#GO:0051234;organelle organization#GO:0006996;endosome transport via multivesicular body sorting pathway#GO:0032509;establishment of localization in cell#GO:0051649;vesicle organization#GO:0016050;intracellular transport#GO:0046907 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endosome membrane#GO:0010008;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle membrane#GO:0030659;late endosome#GO:0005770 membrane traffic protein#PC00150 CIOIN|Ensembl=ENSCING00000021016.1|UniProtKB=H2Y2A4 H2Y2A4 PTHR48105:SF19 THIOREDOXIN REDUCTASE 1-RELATED-RELATED THIOREDOXIN-DISULFIDE REDUCTASE protein-disulfide reductase activity#GO:0015035;disulfide oxidoreductase activity#GO:0015036;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;antioxidant activity#GO:0016209;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 homeostatic process#GO:0042592;cellular homeostasis#GO:0019725 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 reductase#PC00198;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000004174.3|UniProtKB=F7BP82 F7BP82 PTHR11567:SF211 ACID PHOSPHATASE-RELATED PROSTATIC ACID PHOSPHATASE hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 cellular metabolic process#GO:0044237;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;dephosphorylation#GO:0016311;metabolic process#GO:0008152 metabolite interconversion enzyme#PC00262;phosphatase#PC00181 CIOIN|Ensembl=ENSCING00000001371.3|UniProtKB=F6SWM7 F6SWM7 MED15 PTHR31804:SF3 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 15 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 15 CIOIN|Ensembl=ENSCING00000005196.3|UniProtKB=F7B710 F7B710 LOC100185661 PTHR45686:SF4 ADP-RIBOSYLATION FACTOR GTPASE ACTIVATING PROTEIN 3, ISOFORM H-RELATED ADP-RIBOSYLATION FACTOR GTPASE ACTIVATING PROTEIN 3, ISOFORM H vesicle targeting, to, from or within Golgi#GO:0048199;cellular localization#GO:0051641;organelle localization#GO:0051640;vesicle localization#GO:0051648;membrane organization#GO:0061024;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;vesicle targeting#GO:0006903;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;vesicle budding from membrane#GO:0006900;establishment of vesicle localization#GO:0051650;organelle organization#GO:0006996;vesicle organization#GO:0016050;establishment of localization in cell#GO:0051649;establishment of organelle localization#GO:0051656 GTPase-activating protein#PC00257 CIOIN|Ensembl=ENSCING00000002805.3|UniProtKB=F6XMM6 F6XMM6 LOC100176649 PTHR10683:SF18 TRANSALDOLASE TRANSALDOLASE cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 aldolase#PC00044;lyase#PC00144 Pentose phosphate pathway#P02762>Transaldolase#P03081 CIOIN|Ensembl=ENSCING00000009566.3|UniProtKB=Q4H3D5 Q4H3D5 Ci-HNF4 PTHR24083:SF104 NUCLEAR HORMONE RECEPTOR TRANSCRIPTION FACTOR HNF-4 HOMOLOG cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;signaling receptor activity#GO:0038023;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular transducer activity#GO:0060089;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C4 zinc finger nuclear receptor#PC00169;zinc finger transcription factor#PC00244 CIOIN|Ensembl=ENSCING00000005164.3|UniProtKB=F6SKK8 F6SKK8 PTHR43205:SF5 PROSTAGLANDIN REDUCTASE PROSTAGLANDIN REDUCTASE 2 oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor#GO:0016628 lipid metabolic process#GO:0006629;oxoacid metabolic process#GO:0043436;icosanoid metabolic process#GO:0006690;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;prostaglandin metabolic process#GO:0006693;fatty acid metabolic process#GO:0006631;unsaturated fatty acid metabolic process#GO:0033559;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 reductase#PC00198;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000018239.1|UniProtKB=H2XW62 H2XW62 PTHR13376:SF0 INTRAFLAGELLAR TRANSPORT PROTEIN 46 HOMOLOG INTRAFLAGELLAR TRANSPORT PROTEIN 46 HOMOLOG cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;cilium assembly#GO:0060271;cell projection organization#GO:0030030;transport#GO:0006810;microtubule-based movement#GO:0007018;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;transport along microtubule#GO:0010970;cell projection assembly#GO:0030031;intraciliary transport#GO:0042073;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based transport#GO:0099111;microtubule-based process#GO:0007017;establishment of localization#GO:0051234;organelle organization#GO:0006996;cytoskeleton-dependent intracellular transport#GO:0030705;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;protein-containing complex localization#GO:0031503 microtubule organizing center#GO:0005815;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;motile cilium#GO:0031514;intraciliary transport particle B#GO:0030992;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;cell projection#GO:0042995;cilium#GO:0005929;intraciliary transport particle#GO:0030990 CIOIN|Ensembl=ENSCING00000003383.3|UniProtKB=F7A693 F7A693 PTHR46396:SF1 PROTEIN O-LINKED-MANNOSE BETA-1,2-N-ACETYLGLUCOSAMINYLTRANSFERASE 1 PROTEIN O-LINKED-MANNOSE BETA-1,2-N-ACETYLGLUCOSAMINYLTRANSFERASE 1 acetylglucosaminyltransferase activity#GO:0008375;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;UDP-glycosyltransferase activity#GO:0008194 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;protein O-linked glycosylation#GO:0006493;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 bounding membrane of organelle#GO:0098588;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;Golgi membrane#GO:0000139;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000002050.3|UniProtKB=F6TGD6 F6TGD6 LOC100176419 PTHR22803:SF161 MANNOSE, PHOSPHOLIPASE, LECTIN RECEPTOR RELATED C-TYPE LECTIN DOMAIN-CONTAINING PROTEIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 membrane trafficking regulatory protein#PC00151 CIOIN|Ensembl=ENSCING00000009879.3|UniProtKB=F6WTU8 F6WTU8 LOC100175137 PTHR15104:SF0 DIHYDROPTERIDINE REDUCTASE DIHYDROPTERIDINE REDUCTASE nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167;oxidoreductase activity#GO:0016491 cellular aromatic compound metabolic process#GO:0006725;alcohol biosynthetic process#GO:0046165;organonitrogen compound catabolic process#GO:1901565;organic hydroxy compound biosynthetic process#GO:1901617;biosynthetic process#GO:0009058;amino acid catabolic process#GO:0009063;organic cyclic compound metabolic process#GO:1901360;aromatic amino acid metabolic process#GO:0009072;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;alpha-amino acid metabolic process#GO:1901605;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;L-amino acid metabolic process#GO:0170033;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248;organic hydroxy compound metabolic process#GO:1901615;oxoacid metabolic process#GO:0043436;proteinogenic amino acid metabolic process#GO:0170039;heterocycle metabolic process#GO:0046483;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;alcohol metabolic process#GO:0006066;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;aromatic compound catabolic process#GO:0019439;organic cyclic compound catabolic process#GO:1901361;aromatic compound biosynthetic process#GO:0019438;small molecule biosynthetic process#GO:0044283;carboxylic acid metabolic process#GO:0019752;aromatic amino acid family catabolic process#GO:0009074;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 reductase#PC00198;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000007694.3|UniProtKB=F6RVQ6 F6RVQ6 PTHR24039:SF58 FIBRILLIN-RELATED EGF-LIKE DOMAIN-CONTAINING PROTEIN extracellular matrix structural protein#PC00103 CIOIN|Ensembl=ENSCING00000006484.3|UniProtKB=F7ATZ1 F7ATZ1 PTHR24347:SF412 SERINE/THREONINE-PROTEIN KINASE SERINE_THREONINE-PROTEIN KINASE H1 HOMOLOG-RELATED non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CaMK#P00847;Ionotropic glutamate receptor pathway#P00037>CaMKII#P01023 CIOIN|Ensembl=ENSCING00000013146.2|UniProtKB=F6YYL7 F6YYL7 PTHR23010:SF1 MIDNOLIN MIDNOLIN membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000023712.1|UniProtKB=H2Y100 H2Y100 PTHR14374:SF0 FOIE GRAS TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 11 CIOIN|Ensembl=ENSCING00000019765.1|UniProtKB=H2XQ60 H2XQ60 LOC100184464 PTHR35081:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 105 COILED-COIL DOMAIN-CONTAINING PROTEIN 105 CIOIN|Ensembl=ENSCING00000012060.2|UniProtKB=F6Z0L7 F6Z0L7 PTHR21771:SF1 MITOCHONDRIA-EATING PROTEIN-RELATED MITOCHONDRIA-EATING PROTEIN macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;autophagy of mitochondrion#GO:0000422;cellular process#GO:0009987;organelle disassembly#GO:1903008;primary metabolic process#GO:0044238;process utilizing autophagic mechanism#GO:0061919;cellular component organization or biogenesis#GO:0071840;cellular component disassembly#GO:0022411;organelle organization#GO:0006996;nitrogen compound metabolic process#GO:0006807;catabolic process#GO:0009056;mitochondrion organization#GO:0007005;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;autophagy#GO:0006914;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248 envelope#GO:0031975;bounding membrane of organelle#GO:0098588;mitochondrial membrane#GO:0031966;intracellular membrane-bounded organelle#GO:0043231;mitochondrial outer membrane#GO:0005741;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867 CIOIN|Ensembl=ENSCING00000011476.2|UniProtKB=Q1RLE3 Q1RLE3 Ci-ArfGAP-8 PTHR45899:SF2 RHO GTPASE ACTIVATING PROTEIN AT 15B, ISOFORM C RHO GTPASE ACTIVATING PROTEIN AT 15B, ISOFORM C GTPase-activating protein#PC00257 CIOIN|Ensembl=ENSCING00000014208.2|UniProtKB=F6ZPF8 F6ZPF8 LOC100186391 PTHR39490:SF9 ARRESTIN DOMAIN-CONTAINING PROTEIN D FYVE-TYPE DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000009662.3|UniProtKB=F6WU83 F6WU83 LOC100176978 PTHR21624:SF1 STEROL DESATURASE-RELATED PROTEIN ALKYLGLYCEROL MONOOXYGENASE oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497 lipid metabolic process#GO:0006629;membrane lipid metabolic process#GO:0006643;cellular metabolic process#GO:0044237;cellular lipid metabolic process#GO:0044255;cellular process#GO:0009987;metabolic process#GO:0008152;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704 CIOIN|Ensembl=ENSCING00000008800.3|UniProtKB=F6SC91 F6SC91 LOC100184049 PTHR16684:SF11 CENTROMERE PROTEIN C CENTROMERE PROTEIN C sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;protein-DNA complex organization#GO:0071824;kinetochore organization#GO:0051383;organelle localization#GO:0051640;homologous chromosome segregation#GO:0045143;nuclear division#GO:0000280;attachment of mitotic spindle microtubules to kinetochore#GO:0051315;cell cycle process#GO:0022402;protein-containing complex assembly#GO:0065003;protein-DNA complex assembly#GO:0065004;mitotic cell cycle process#GO:1903047;chromosome segregation#GO:0007059;mitotic cell cycle#GO:0000278;establishment of localization#GO:0051234;meiotic cell cycle process#GO:1903046;meiosis I cell cycle process#GO:0061982;reproductive process#GO:0022414;attachment of spindle microtubules to kinetochore#GO:0008608;mitotic nuclear division#GO:0140014;mitotic sister chromatid segregation#GO:0000070;kinetochore assembly#GO:0051382;non-membrane-bounded organelle assembly#GO:0140694;establishment of organelle localization#GO:0051656;meiosis I#GO:0007127;cellular component assembly#GO:0022607;nuclear chromosome segregation#GO:0098813;sister chromatid segregation#GO:0000819;establishment of chromosome localization#GO:0051303;meiotic cell cycle#GO:0051321;cellular component organization#GO:0016043;cellular process#GO:0009987;meiotic chromosome segregation#GO:0045132;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;reproduction#GO:0000003;mitotic metaphase chromosome alignment#GO:0007080;meiotic nuclear division#GO:0140013;organelle organization#GO:0006996;chromosome organization#GO:0051276;protein-containing complex organization#GO:0043933;sexual reproduction#GO:0019953;cell cycle#GO:0007049;organelle fission#GO:0048285;establishment of localization in cell#GO:0051649;chromosome localization#GO:0050000;metaphase chromosome alignment#GO:0051310 centromere DNA-binding protein#PC00071 CIOIN|Ensembl=ENSCING00000022764.1|UniProtKB=H2XW91 H2XW91 PTHR10869:SF244 PROLYL 4-HYDROXYLASE ALPHA SUBUNIT PROLYL 4-HYDROXYLASE SUBUNIT ALPHA-2 2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;dioxygenase activity#GO:0051213 oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular modified amino acid metabolic process#GO:0006575;protein hydroxylation#GO:0018126;alpha-amino acid metabolic process#GO:1901605;protein metabolic process#GO:0019538;carboxylic acid metabolic process#GO:0019752;L-amino acid metabolic process#GO:0170033;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000002379.3|UniProtKB=F6R4Z1 F6R4Z1 LOC100182434 PTHR12305:SF81 PHOSPHATASE WITH HOMOLOGY TO TENSIN PHOSPHATIDYLINOSITOL 3,4,5-TRISPHOSPHATE 3-PHOSPHATASE AND DUAL-SPECIFICITY PROTEIN PHOSPHATASE PTEN hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 cellular metabolic process#GO:0044237;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;metabolic process#GO:0008152;phosphate-containing compound metabolic process#GO:0006796;dephosphorylation#GO:0016311 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 protein phosphatase#PC00195;protein modifying enzyme#PC00260 p53 pathway#P00059>PTEN#G01579;p53 pathway feedback loops 2#P04398>PTEN#G04714;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>PTEN#P00905;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>PTEN#G04675;p53 pathway#P00059>PTEN#P01480;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PTEN#P00849;Hypoxia response via HIF activation#P00030>PTEN#P00824;PI3 kinase pathway#P00048>PTEN#P01189;CCKR signaling map#P06959>PTEN#P07071;p53 pathway feedback loops 2#P04398>PTEN#P04658 CIOIN|Ensembl=ENSCING00000017107.2|UniProtKB=F6WFW0 F6WFW0 LOC100183603 PTHR23415:SF29 CYCLIN-DEPENDENT KINASES REGULATORY SUBUNIT/60S RIBOSOME SUBUNIT BIOGENESIS PROTEIN NIP7 CYCLIN-DEPENDENT KINASES REGULATORY SUBUNIT-RELATED protein kinase regulator activity#GO:0019887;molecular function activator activity#GO:0140677;binding#GO:0005488;molecular function regulator activity#GO:0098772;enzyme binding#GO:0019899;enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;histone binding#GO:0042393;kinase regulator activity#GO:0019207;kinase binding#GO:0019900;kinase activator activity#GO:0019209;protein kinase activator activity#GO:0030295;ubiquitin-like protein binding#GO:0032182;protein serine/threonine kinase activator activity#GO:0043539;ubiquitin binding#GO:0043130;protein binding#GO:0005515;protein kinase binding#GO:0019901 biological regulation#GO:0065007;regulation of biological process#GO:0050789;regulation of cell cycle#GO:0051726;regulation of mitotic cell cycle#GO:0007346;regulation of cellular process#GO:0050794 SCF ubiquitin ligase complex#GO:0019005;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;cullin-RING ubiquitin ligase complex#GO:0031461;catalytic complex#GO:1902494;transferase complex#GO:1990234;serine/threonine protein kinase complex#GO:1902554;protein kinase complex#GO:1902911;intracellular protein-containing complex#GO:0140535;transferase complex, transferring phosphorus-containing groups#GO:0061695 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000005546.3|UniProtKB=F6XEP4 F6XEP4 LOC100178431 PTHR10845:SF254 REGULATOR OF G PROTEIN SIGNALING RGS DOMAIN-CONTAINING PROTEIN-RELATED G-protein modulator#PC00022;protein-binding activity modulator#PC00095;GTPase-activating protein#PC00257 CIOIN|Ensembl=ENSCING00000002640.3|UniProtKB=F6ZJ18 F6ZJ18 LOC100182244 PTHR10822:SF30 GLYPICAN DALLY-LIKE, ISOFORM A regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of protein localization to membrane#GO:1905475;biological regulation#GO:0065007;regulation of localization#GO:0032879;cell motility#GO:0048870;cellular process#GO:0009987;cell migration#GO:0016477;regulation of cellular localization#GO:0060341;regulation of protein localization#GO:0032880 cell surface#GO:0009986;extracellular matrix#GO:0031012;synapse#GO:0045202;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;cell junction#GO:0030054;collagen-containing extracellular matrix#GO:0062023;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000002439.3|UniProtKB=F6QD80 F6QD80 PTHR10334:SF590 CYSTEINE-RICH SECRETORY PROTEIN-RELATED SCP DOMAIN-CONTAINING PROTEIN extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 defense/immunity protein#PC00090 CIOIN|Ensembl=ENSCING00000017354.2|UniProtKB=F6UNK6 F6UNK6 PTHR24412:SF172 KELCH PROTEIN KELCH-LIKE PROTEIN 10 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000008102.3|UniProtKB=F6YNE2 F6YNE2 arnt PTHR23042:SF76 CIRCADIAN PROTEIN CLOCK/ARNT/BMAL/PAS ARYL HYDROCARBON RECEPTOR NUCLEAR TRANSLOCATOR HOMOLOG sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 receptor complex#GO:0043235;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 basic helix-loop-helix transcription factor#PC00055 CIOIN|Ensembl=ENSCING00000006362.3|UniProtKB=F6RS38 F6RS38 PTHR11848:SF270 TGF-BETA FAMILY BONE MORPHOGENETIC PROTEIN 3-LIKE molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;cytokine activity#GO:0005125;protein binding#GO:0005515;signaling receptor binding#GO:0005102 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 CIOIN|Ensembl=ENSCING00000018117.1|UniProtKB=H2Y099 H2Y099 PTHR24256:SF545 TRYPTASE-RELATED INACTIVE SERINE PROTEASE 54 hydrolase activity#GO:0016787;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 serine protease#PC00203;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000000345.3|UniProtKB=F6WDS6 F6WDS6 PTHR21245:SF2 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN RNA-BINDING PROTEIN 18-RELATED nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000019030.1|UniProtKB=H2XLM9 H2XLM9 PTHR12859:SF0 PRA1 PROTEIN PRA1 FAMILY PROTEIN cellular anatomical entity#GO:0110165;membrane#GO:0016020 amino acid transporter#PC00046;secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000004888.3|UniProtKB=F6SNK4 F6SNK4 PTHR42753:SF9 MITOCHONDRIAL RIBOSOME PROTEIN L39/PROLYL-TRNA LIGASE FAMILY MEMBER LARGE RIBOSOMAL SUBUNIT PROTEIN ML39 catalytic activity, acting on RNA#GO:0140098;ligase activity#GO:0016874;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;catalytic activity, acting on a nucleic acid#GO:0140640 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;peptide biosynthetic process#GO:0043043;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 aminoacyl-tRNA synthetase#PC00047;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000012722.2|UniProtKB=F7AT69 F7AT69 PTHR24372:SF77 GLYCOPROTEIN HORMONE RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 response to organic substance#GO:0010033;positive regulation of adenylate cyclase activity#GO:0045762;regulation of lyase activity#GO:0051339;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;cellular response to stimulus#GO:0051716;regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;cellular response to endogenous stimulus#GO:0071495;cellular response to chemical stimulus#GO:0070887;positive regulation of catalytic activity#GO:0043085;cellular response to organic substance#GO:0071310;regulation of cyclase activity#GO:0031279;positive regulation of molecular function#GO:0044093;cell communication#GO:0007154;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;positive regulation of cyclase activity#GO:0031281;hormone-mediated signaling pathway#GO:0009755;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to endogenous stimulus#GO:0009719;response to hormone#GO:0009725;cellular response to hormone stimulus#GO:0032870;response to chemical#GO:0042221;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of lyase activity#GO:0051349;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 CIOIN|Ensembl=ENSCING00000004140.3|UniProtKB=F6UI47 F6UI47 PTHR11817:SF3 PYRUVATE KINASE AT14039P-RELATED transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;ribonucleoside triphosphate metabolic process#GO:0009199;nucleoside triphosphate metabolic process#GO:0009141;carbohydrate derivative metabolic process#GO:1901135;heterocycle catabolic process#GO:0046700;organonitrogen compound catabolic process#GO:1901565;ribonucleotide catabolic process#GO:0009261;pyridine nucleotide metabolic process#GO:0019362;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;cellular nitrogen compound catabolic process#GO:0044270;purine-containing compound catabolic process#GO:0072523;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;purine nucleotide catabolic process#GO:0006195;ATP metabolic process#GO:0046034;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;purine ribonucleotide catabolic process#GO:0009154;nucleoside phosphate metabolic process#GO:0006753;carbohydrate catabolic process#GO:0016052;purine-containing compound metabolic process#GO:0072521;pyridine-containing compound metabolic process#GO:0072524;catabolic process#GO:0009056;nucleoside diphosphate metabolic process#GO:0009132;organic substance catabolic process#GO:1901575;carbohydrate metabolic process#GO:0005975;purine nucleotide metabolic process#GO:0006163;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;oxoacid metabolic process#GO:0043436;nucleoside phosphate catabolic process#GO:1901292;carbohydrate derivative catabolic process#GO:1901136;purine ribonucleoside triphosphate metabolic process#GO:0009205;generation of precursor metabolites and energy#GO:0006091;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;nucleotide catabolic process#GO:0009166;cellular nitrogen compound metabolic process#GO:0034641;nicotinamide nucleotide metabolic process#GO:0046496;cellular process#GO:0009987;nucleoside diphosphate catabolic process#GO:0009134;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;organophosphate catabolic process#GO:0046434;aromatic compound catabolic process#GO:0019439;glycolytic process#GO:0006096;organic cyclic compound catabolic process#GO:1901361;organophosphate metabolic process#GO:0019637;purine nucleoside triphosphate metabolic process#GO:0009144;nucleobase-containing compound catabolic process#GO:0034655;nucleotide metabolic process#GO:0009117;carboxylic acid metabolic process#GO:0019752;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 kinase#PC00137 Pyruvate metabolism#P02772>Pyruvate Kinase#P03132 CIOIN|Ensembl=ENSCING00000004381.3|UniProtKB=F7BD80 F7BD80 PTHR10933:SF9 IMMUNOGLOBULIN-BINDING PROTEIN 1 IMMUNOGLOBULIN-BINDING PROTEIN 1 phosphatase binding#GO:0019902;enzyme binding#GO:0019899;protein binding#GO:0005515;protein phosphatase binding#GO:0019903;binding#GO:0005488 regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;regulation of phosphate metabolic process#GO:0019220;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of dephosphorylation#GO:0035303;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 chaperone#PC00072 CIOIN|Ensembl=ENSCING00000005613.3|UniProtKB=F7AT12 F7AT12 PTHR45858:SF5 FERM DOMAIN CONTAINING PROTEIN MOESIN_EZRIN_RADIXIN HOMOLOG 1 nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 CIOIN|Ensembl=ENSCING00000012142.2|UniProtKB=F6UIH2 F6UIH2 zf(c2h2)-24 PTHR23235:SF156 KRUEPPEL-LIKE TRANSCRIPTION FACTOR KRUPPEL-LIKE FACTOR 18 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 CIOIN|Ensembl=ENSCING00000001880.3|UniProtKB=F6SJG5 F6SJG5 PTHR22906:SF43 PROPERDIN PROPERDIN CIOIN|Ensembl=ENSCING00000019844.1|UniProtKB=H2XQY9 H2XQY9 LOC100176521 PTHR10671:SF108 EPITHELIAL MEMBRANE PROTEIN-RELATED CLAUDIN FAMILY PROTEIN-RELATED cytoskeletal protein#PC00085 CIOIN|Ensembl=ENSCING00000000529.3|UniProtKB=Q4H2L1 Q4H2L1 Ci-ZF(BTB_C2H2) PTHR24409:SF295 ZINC FINGER PROTEIN 142 AZ2-RELATED sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 CIOIN|Ensembl=ENSCING00000023096.1|UniProtKB=H2XWK0 H2XWK0 PTHR12232:SF15 SH3 DOMAIN-BINDING GLUTAMIC ACID-RICH-LIKE PROTEIN SH3 DOMAIN-BINDING GLUTAMIC ACID-RICH PROTEIN HOMOLOG cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000001947.3|UniProtKB=F6XU21 F6XU21 PTHR24373:SF393 SLIT RELATED LEUCINE-RICH REPEAT NEURONAL PROTEIN PROTEIN SLIT-LIKE PROTEIN transmembrane signal receptor#PC00197 CIOIN|Ensembl=ENSCING00000002585.3|UniProtKB=F6UEE4 F6UEE4 LOC100182475 PTHR13948:SF3 RNA-BINDING PROTEIN FI21118P1 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000007946.3|UniProtKB=F6ZRB6 F6ZRB6 LOC100177476 PTHR11599:SF10 PROTEASOME SUBUNIT ALPHA/BETA PROTEASOME SUBUNIT ALPHA TYPE-3 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 peptidase complex#GO:1905368;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;proteasome complex#GO:0000502;endopeptidase complex#GO:1905369;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protease#PC00190;protein modifying enzyme#PC00260 Parkinson disease#P00049>20S proteasome#P01227 CIOIN|Ensembl=ENSCING00000000152.3|UniProtKB=F6ZHM4 F6ZHM4 LOC100176223 PTHR43381:SF20 TRANSLATION INITIATION FACTOR IF-2-RELATED TRANSLATION INITIATION FACTOR IF-2, MITOCHONDRIAL nucleic acid binding#GO:0003676;translation regulator activity#GO:0045182;translation regulator activity, nucleic acid binding#GO:0090079;binding#GO:0005488;organic cyclic compound binding#GO:0097159;translation initiation factor activity#GO:0003743;translation factor activity, RNA binding#GO:0008135 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;translational initiation#GO:0006413;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 translation initiation factor#PC00224;translation factor#PC00223;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000005264.3|UniProtKB=F6V9J8 F6V9J8 LOC100179755 PTHR42985:SF2 SODIUM-COUPLED MONOCARBOXYLATE TRANSPORTER SODIUM-DEPENDENT MULTIVITAMIN TRANSPORTER symporter activity#GO:0015293;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 localization#GO:0051179;monoatomic cation transport#GO:0006812;sodium ion transport#GO:0006814;metal ion transport#GO:0030001;establishment of localization#GO:0051234;monoatomic ion transport#GO:0006811;transport#GO:0006810 secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000024163.1|UniProtKB=A0A1W2WFK8 A0A1W2WFK8 LOC100176226 PTHR11732:SF506 ALDO/KETO REDUCTASE ALDO-KETO REDUCTASE 1B, ISOFORM C-RELATED oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 reductase#PC00198;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000008645.3|UniProtKB=F6ZYU1 F6ZYU1 LOC100179669 PTHR43968:SF6 FAMILY NOT NAMED GLUTATHIONE S-TRANSFERASE OMEGA cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000024205.1|UniProtKB=H2Y2G8 H2Y2G8 PTHR22977:SF5 COX ASSEMBLY MITOCHONDRIAL PROTEIN COX ASSEMBLY MITOCHONDRIAL PROTEIN HOMOLOG cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000009984.3|UniProtKB=F6QME2 F6QME2 PTHR46105:SF28 AGAP004733-PA ZINC FINGER PROTEIN 37-LIKE sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 CIOIN|Ensembl=ENSCING00000007801.3|UniProtKB=F6X383 F6X383 ciad70l24 PTHR22750:SF57 G-PROTEIN COUPLED RECEPTOR RHODOPSIN, GQ-COUPLED-LIKE signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052;regulation of metabolic process#GO:0019222 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 CIOIN|Ensembl=ENSCING00000011490.2|UniProtKB=F6WVC9 F6WVC9 LOC100184605 PTHR13522:SF3 U6 SNRNA PHOSPHODIESTERASE 1 U6 SNRNA PHOSPHODIESTERASE 1 catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;catalytic activity#GO:0003824;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters#GO:0016796;hydrolase activity#GO:0016787;catalytic activity, acting on a nucleic acid#GO:0140640;3'-5'-RNA exonuclease activity#GO:0000175;exonuclease activity#GO:0004527;3'-5' exonuclease activity#GO:0008408;RNA nuclease activity#GO:0004540 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;snRNA metabolic process#GO:0016073;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;snRNA 3'-end processing#GO:0034472;snRNA processing#GO:0016180;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000016336.2|UniProtKB=F6VHD2 F6VHD2 LOC100184416 PTHR24024:SF19 PULMONARY SURFACTANT-ASSOCIATED PROTEIN A FARMER, ISOFORM H extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 surfactant#PC00212;structural protein#PC00211 CIOIN|Ensembl=ENSCING00000008912.3|UniProtKB=F6QB35 F6QB35 LOC100183428 PTHR12205:SF0 CENTROMERE/KINETOCHORE PROTEIN ZW10 CENTROMERE_KINETOCHORE PROTEIN ZW10 HOMOLOG endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;negative regulation of sister chromatid segregation#GO:0033046;negative regulation of mitotic sister chromatid separation#GO:2000816;cellular localization#GO:0051641;negative regulation of biological process#GO:0048519;regulation of mitotic nuclear division#GO:0007088;signal transduction#GO:0007165;negative regulation of mitotic metaphase/anaphase transition#GO:0045841;regulation of chromosome segregation#GO:0051983;mitotic cell cycle checkpoint signaling#GO:0007093;negative regulation of chromosome organization#GO:2001251;regulation of chromosome separation#GO:1905818;negative regulation of mitotic nuclear division#GO:0045839;transport#GO:0006810;cell cycle process#GO:0022402;regulation of cellular component organization#GO:0051128;negative regulation of cell cycle process#GO:0010948;negative regulation of nuclear division#GO:0051784;negative regulation of mitotic sister chromatid segregation#GO:0033048;mitotic cell cycle process#GO:1903047;regulation of biological process#GO:0050789;cell cycle checkpoint signaling#GO:0000075;negative regulation of mitotic cell cycle phase transition#GO:1901991;mitotic cell cycle#GO:0000278;establishment of localization#GO:0051234;negative regulation of organelle organization#GO:0010639;regulation of mitotic sister chromatid segregation#GO:0033047;intracellular signal transduction#GO:0035556;negative regulation of cellular component organization#GO:0051129;negative regulation of cellular process#GO:0048523;signaling#GO:0023052;regulation of chromosome organization#GO:0033044;cellular response to stimulus#GO:0051716;regulation of mitotic sister chromatid separation#GO:0010965;regulation of nuclear division#GO:0051783;negative regulation of cell cycle#GO:0045786;regulation of mitotic cell cycle phase transition#GO:1901990;regulation of organelle organization#GO:0033043;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;mitotic spindle assembly checkpoint signaling#GO:0007094;negative regulation of chromosome segregation#GO:0051985;regulation of cell cycle phase transition#GO:1901987;negative regulation of cell cycle phase transition#GO:1901988;vesicle-mediated transport#GO:0016192;negative regulation of mitotic cell cycle#GO:0045930;cell communication#GO:0007154;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;regulation of mitotic metaphase/anaphase transition#GO:0030071;regulation of cell cycle process#GO:0010564;localization#GO:0051179;response to stimulus#GO:0050896;negative regulation of chromosome separation#GO:1905819;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;regulation of sister chromatid segregation#GO:0033045;regulation of mitotic cell cycle#GO:0007346;negative regulation of metaphase/anaphase transition of cell cycle#GO:1902100 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;kinetochore#GO:0000776;chromosome#GO:0005694;condensed chromosome, centromeric region#GO:0000779;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;chromosomal region#GO:0098687;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 microtubule or microtubule-binding cytoskeletal protein#PC00157 CIOIN|Ensembl=ENSCING00000006851.3|UniProtKB=F6ZXN6 F6ZXN6 LOC100174990 PTHR45652:SF21 GLIAL FIBRILLARY ACIDIC PROTEIN ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 13-LIKE ISOFORM X1 structural molecule activity#GO:0005198;structural constituent of cytoskeleton#GO:0005200 cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;intermediate filament organization#GO:0045109;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cellular process#GO:0009987;intermediate filament cytoskeleton organization#GO:0045104;intermediate filament-based process#GO:0045103 supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intermediate filament#GO:0005882;intermediate filament cytoskeleton#GO:0045111;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;supramolecular fiber#GO:0099512;supramolecular polymer#GO:0099081;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 intermediate filament#PC00129 CIOIN|Ensembl=ENSCING00000005985.3|UniProtKB=F6PWP3 F6PWP3 PTHR14222:SF2 CONDENSIN CONDENSIN COMPLEX SUBUNIT 1 protein binding#GO:0005515;histone binding#GO:0042393;binding#GO:0005488 nuclear chromosome segregation#GO:0098813;sister chromatid segregation#GO:0000819;meiotic cell cycle#GO:0051321;nuclear division#GO:0000280;cell cycle process#GO:0022402;chromosome condensation#GO:0030261;cellular component organization#GO:0016043;cellular process#GO:0009987;mitotic cell cycle process#GO:1903047;mitotic chromosome condensation#GO:0007076;chromosome segregation#GO:0007059;cellular component organization or biogenesis#GO:0071840;chromosome organization involved in meiotic cell cycle#GO:0070192;mitotic cell cycle#GO:0000278;reproduction#GO:0000003;organelle organization#GO:0006996;chromosome organization#GO:0051276;meiotic cell cycle process#GO:1903046;sexual reproduction#GO:0019953;reproductive process#GO:0022414;cell cycle#GO:0007049;mitotic nuclear division#GO:0140014;organelle fission#GO:0048285;mitotic sister chromatid segregation#GO:0000070 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;condensed chromosome, centromeric region#GO:0000779;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;chromosomal region#GO:0098687;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 CIOIN|Ensembl=ENSCING00000013886.2|UniProtKB=F6Q249 F6Q249 PTHR21041:SF9 DENDRITIC CELL-SPECIFIC TRANSMEMBRANE PROTEIN DENDRITIC CELL-SPECIFIC TRANSMEMBRANE PROTEIN-LIKE DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000008017.3|UniProtKB=F6SSP0 F6SSP0 LOC100176522 PTHR22780:SF5 ADAPTIN, ALPHA/GAMMA/EPSILON AP-1 COMPLEX SUBUNIT GAMMA molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 localization#GO:0051179;cellular localization#GO:0051641;Golgi to vacuole transport#GO:0006896;establishment of localization#GO:0051234;vacuolar transport#GO:0007034;post-Golgi vesicle-mediated transport#GO:0006892;transport#GO:0006810;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987 bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;clathrin vesicle coat#GO:0030125;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;AP-type membrane coat adaptor complex#GO:0030119;transport vesicle membrane#GO:0030658;clathrin-coated vesicle#GO:0030136;membrane coat#GO:0030117;coated membrane#GO:0048475;cytoplasmic vesicle membrane#GO:0030659;trans-Golgi network transport vesicle#GO:0030140;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;membrane#GO:0016020;coated vesicle#GO:0030135;vesicle coat#GO:0030120;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;Golgi-associated vesicle membrane#GO:0030660;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;coated vesicle membrane#GO:0030662;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;Golgi-associated vesicle#GO:0005798;transport vesicle#GO:0030133 membrane traffic protein#PC00150 CIOIN|Ensembl=ENSCING00000004622.3|UniProtKB=F6VXM0 F6VXM0 PTHR10138:SF0 TRYPTOPHAN 2,3-DIOXYGENASE TRYPTOPHAN 2,3-DIOXYGENASE oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;dioxygenase activity#GO:0051213;tetrapyrrole binding#GO:0046906;oxidoreductase activity#GO:0016491;heme binding#GO:0020037 cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;heterocycle catabolic process#GO:0046700;biogenic amine metabolic process#GO:0006576;organonitrogen compound catabolic process#GO:1901565;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;cellular nitrogen compound catabolic process#GO:0044270;amino acid catabolic process#GO:0009063;organic cyclic compound metabolic process#GO:1901360;aromatic amino acid metabolic process#GO:0009072;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;alpha-amino acid metabolic process#GO:1901605;purine-containing compound metabolic process#GO:0072521;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;amide metabolic process#GO:0043603;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;amine metabolic process#GO:0009308;acyl-CoA metabolic process#GO:0006637;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;aromatic compound catabolic process#GO:0019439;small molecule catabolic process#GO:0044282;organic cyclic compound catabolic process#GO:1901361;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;carboxylic acid metabolic process#GO:0019752;aromatic amino acid family catabolic process#GO:0009074;amino acid metabolic process#GO:0006520;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 oxygenase#PC00177;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000014980.2|UniProtKB=F6RSE2 F6RSE2 PTHR23226:SF371 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 112-LIKE PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 CIOIN|Ensembl=ENSCING00000013817.2|UniProtKB=F6QRC2 F6QRC2 LOC100181213 PTHR23055:SF172 CALCIUM BINDING PROTEINS EF-HAND DOMAIN-CONTAINING PROTEIN cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488 calmodulin-related#PC00061 CIOIN|Ensembl=ENSCING00000016996.2|UniProtKB=F7A102 F7A102 PTHR46507:SF4 AFADIN- AND ALPHA-ACTININ-BINDING PROTEIN SSX FAMILY MEMBER 2 INTERACTING PROTEIN cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;cilium assembly#GO:0060271;cell projection organization#GO:0030030;transport#GO:0006810;microtubule-based movement#GO:0007018;cellular component organization#GO:0016043;intraciliary transport involved in cilium assembly#GO:0035735;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;transport along microtubule#GO:0010970;cell projection assembly#GO:0030031;intraciliary transport#GO:0042073;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based transport#GO:0099111;microtubule-based process#GO:0007017;establishment of localization#GO:0051234;organelle organization#GO:0006996;cytoskeleton-dependent intracellular transport#GO:0030705;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;protein-containing complex localization#GO:0031503 microtubule organizing center#GO:0005815;centriolar satellite#GO:0034451;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;centrosome#GO:0005813;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;ciliary basal body#GO:0036064;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;cell projection#GO:0042995;cilium#GO:0005929 CIOIN|Ensembl=ENSCING00000000748.3|UniProtKB=F6PVI5 F6PVI5 LOC100181012 PTHR43651:SF3 1,4-ALPHA-GLUCAN-BRANCHING ENZYME 1,4-ALPHA-GLUCAN-BRANCHING ENZYME transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 carbohydrate metabolic process#GO:0005975;organic substance metabolic process#GO:0071704;primary metabolic process#GO:0044238;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 amylase#PC00048;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000000549.3|UniProtKB=F6Q874 F6Q874 PTHR24026:SF136 FAT ATYPICAL CADHERIN-RELATED PROTOCADHERIN-23 cell adhesion molecule#PC00069;cadherin#PC00057 CIOIN|Ensembl=ENSCING00000022685.1|UniProtKB=H2XXY9 H2XXY9 PTHR23104:SF17 MULTIPLE COAGULATION FACTOR DEFICIENCY PROTEIN 2 NEURAL STEM CELL DERIVED NEURONAL SURVIVAL PROTEIN EF-HAND DOMAIN-CONTAINING PROTEIN membrane traffic protein#PC00150 CIOIN|Ensembl=ENSCING00000005789.3|UniProtKB=F6RGG4 F6RGG4 LOC100185405 PTHR10218:SF212 GTP-BINDING PROTEIN ALPHA SUBUNIT G PROTEIN ALPHA S SUBUNIT GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;ribonucleoside triphosphate phosphatase activity#GO:0017111;G protein-coupled receptor binding#GO:0001664;signaling receptor binding#GO:0005102 response to organic substance#GO:0010033;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;response to organic cyclic compound#GO:0014070;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cellular response to endogenous stimulus#GO:0071495;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;cellular response to organic substance#GO:0071310;response to organonitrogen compound#GO:0010243;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to nitrogen compound#GO:1901699;response to nitrogen compound#GO:1901698;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;response to chemical#GO:0042221;dopamine receptor signaling pathway#GO:0007212;cellular response to organonitrogen compound#GO:0071417;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cellular response to organic cyclic compound#GO:0071407;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052 cytoplasm#GO:0005737;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;cytoplasmic side of plasma membrane#GO:0009898;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622;extrinsic component of membrane#GO:0019898 heterotrimeric G-protein#PC00117;G-protein#PC00020 5HT4 type receptor mediated signaling pathway#P04376>G-protein#P04430;Endothelin signaling pathway#P00019>Gs#P00584;Enkephalin release#P05913>G-Protein (s)#P05977;Histamine H2 receptor mediated signaling pathway#P04386>G-Protein#P04490;Beta3 adrenergic receptor signaling pathway#P04379>G-Protein#P04448;Beta1 adrenergic receptor signaling pathway#P04377>G-Protein#P04436;Beta2 adrenergic receptor signaling pathway#P04378>G-Protein#P04443;Cortocotropin releasing factor receptor signaling pathway#P04380>G-Protein#P04458 CIOIN|Ensembl=ENSCING00000009752.3|UniProtKB=F7ABT2 F7ABT2 PTHR22625:SF70 PLEXIN PLEXIN A, ISOFORM A transmembrane signal receptor#PC00197 CIOIN|Ensembl=ENSCING00000009598.3|UniProtKB=F7AWX4 F7AWX4 PTHR11984:SF53 CONNEXIN GAP JUNCTION PROTEIN wide pore channel activity#GO:0022829;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;channel activity#GO:0015267 biological regulation#GO:0065007;regulation of biological process#GO:0050789;cell communication#GO:0007154;cellular process#GO:0009987;cell-cell signaling#GO:0007267;signaling#GO:0023052 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 cell junction protein#PC00070;gap junction#PC00105 CIOIN|Ensembl=ENSCING00000017046.2|UniProtKB=F6X2R6 F6X2R6 PTHR31711:SF1 ARGININE AND GLUTAMATE-RICH PROTEIN 1 ARGININE AND GLUTAMATE-RICH PROTEIN 1 cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;binding#GO:0005488 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000019409.1|UniProtKB=H2XST5 H2XST5 PTHR11559:SF424 CARBOXYLESTERASE CARBOXYLESTERASE 1D-LIKE ISOFORM X1 esterase#PC00097;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000025053.1|UniProtKB=H2XRX2 H2XRX2 PTHR24064:SF577 SOLUTE CARRIER FAMILY 22 MEMBER GH09241P secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000023616.1|UniProtKB=F7BLX7 F7BLX7 PTHR10155:SF10 PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT PI3K21B, ISOFORM B enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207 lipid metabolic process#GO:0006629;phospholipid biosynthetic process#GO:0008654;organophosphate biosynthetic process#GO:0090407;phosphatidylinositol biosynthetic process#GO:0006661;glycerolipid biosynthetic process#GO:0045017;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;phosphatidylinositol metabolic process#GO:0046488;glycerophospholipid metabolic process#GO:0006650;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;phosphatidylinositol phosphate biosynthetic process#GO:0046854;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;glycerophospholipid biosynthetic process#GO:0046474;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;phosphatidylinositol 3-kinase complex#GO:0005942;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;membrane#GO:0016020;transferase complex, transferring phosphorus-containing groups#GO:0061695;extrinsic component of membrane#GO:0019898 kinase modulator#PC00140 p53 pathway feedback loops 2#P04398>PI3K#P04661;p53 pathway#P00059>PI3K#P04609;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>PI3K#P00900;Endothelin signaling pathway#P00019>PI3K#P00577;Angiogenesis#P00005>PI3K#P00236;Integrin signalling pathway#P00034>PI3K#P00936;VEGF signaling pathway#P00056>PI3K#P01413 CIOIN|Ensembl=ENSCING00000003410.3|UniProtKB=F6ZMB2 F6ZMB2 PTHR24361:SF613 MITOGEN-ACTIVATED KINASE KINASE KINASE NUCLEAR RECEPTOR-BINDING PROTEIN-RELATED transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000008368.3|UniProtKB=F7A1S8 F7A1S8 PTHR10953:SF102 UBIQUITIN-ACTIVATING ENZYME E1 ADENYLYLTRANSFERASE AND SULFURTRANSFERASE MOCS3 thiosulfate sulfurtransferase activity#GO:0004792;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824;sulfurtransferase activity#GO:0016783;nucleotidyltransferase activity#GO:0016779 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000005991.3|UniProtKB=F6V5A7 F6V5A7 PTHR11640:SF164 NEPHRIN MAM DOMAIN-CONTAINING GLYCOSYLPHOSPHATIDYLINOSITOL ANCHOR PROTEIN 1 cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;binding#GO:0005488 cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987 cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;plasma membrane#GO:0005886 immunoglobulin superfamily cell adhesion molecule#PC00125;cell adhesion molecule#PC00069 CIOIN|Ensembl=ENSCING00000007927.3|UniProtKB=F6WR85 F6WR85 PTHR22912:SF151 DISULFIDE OXIDOREDUCTASE DIHYDROLIPOYL DEHYDROGENASE, MITOCHONDRIAL nucleotide binding#GO:0000166;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;flavin adenine dinucleotide binding#GO:0050660;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167;oxidoreductase activity#GO:0016491 oxoacid metabolic process#GO:0043436;dicarboxylic acid metabolic process#GO:0043648;cellular metabolic process#GO:0044237;cellular process#GO:0009987;carboxylic acid metabolic process#GO:0019752;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000004599.3|UniProtKB=F6U2M6 F6U2M6 PTHR23127:SF0 CENTROMERE/MICROTUBULE BINDING PROTEIN CBF5 H_ACA RIBONUCLEOPROTEIN COMPLEX SUBUNIT DKC1 isomerase activity#GO:0016853;intramolecular transferase activity#GO:0016866;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;RNA modification#GO:0009451;rRNA modification#GO:0000154;RNA processing#GO:0006396;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;ncRNA metabolic process#GO:0034660;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;ribosome biogenesis#GO:0042254;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;snRNA metabolic process#GO:0016073;macromolecule biosynthetic process#GO:0009059;RNA 3'-end processing#GO:0031123;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;mRNA modification#GO:0016556;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;pseudouridine synthesis#GO:0001522;nucleic acid metabolic process#GO:0090304;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613 centromere DNA-binding protein#PC00071 CIOIN|Ensembl=ENSCING00000007164.3|UniProtKB=F6ZB81 F6ZB81 LOC494372 PTHR24248:SF200 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR 5-HYDROXYTRYPTAMINE RECEPTOR 1B-LIKE ISOFORM X1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of MAPK cascade#GO:0043408;signal transduction#GO:0007165;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;cell communication#GO:0007154;cellular process#GO:0009987;regulation of intracellular signal transduction#GO:1902531;positive regulation of MAPK cascade#GO:0043410;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 CIOIN|Ensembl=ENSCING00000021639.1|UniProtKB=H2XV00 H2XV00 PTHR45632:SF27 LD33804P KELCH-LIKE PROTEIN 9 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000013902.2|UniProtKB=F6PWA8 F6PWA8 PTHR46135:SF3 NME/NM23 FAMILY MEMBER 8 NME_NM23 FAMILY MEMBER 8 CIOIN|Ensembl=ENSCING00000024049.1|UniProtKB=H2Y3K2 H2Y3K2 LOC100176204 PTHR13848:SF2 PROTEIN YIPPEE-LIKE CG15309-RELATED PROTEIN YIPPEE-LIKE ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000002837.3|UniProtKB=Q1RLG9 Q1RLG9 Ci-ArfGAP-3 PTHR46097:SF3 G PROTEIN-COUPLED RECEPTOR KINASE INTERACTING ARFGAP ARF GTPASE-ACTIVATING PROTEIN GIT nucleoside-triphosphatase regulator activity#GO:0060589;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;binding#GO:0005488;molecular function regulator activity#GO:0098772;enzyme binding#GO:0019899;protein binding#GO:0005515;enzyme activator activity#GO:0008047;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234 regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;regulation of signaling#GO:0023051;biological regulation#GO:0065007;regulation of G protein-coupled receptor signaling pathway#GO:0008277;regulation of intracellular signal transduction#GO:1902531;regulation of small GTPase mediated signal transduction#GO:0051056 CIOIN|Ensembl=ENSCING00000002807.3|UniProtKB=A0A1W5BHL0 A0A1W5BHL0 LOC100182009 PTHR32251:SF17 3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE STEROID 5-ALPHA REDUCTASE C-TERMINAL DOMAIN-CONTAINING PROTEIN cellular anatomical entity#GO:0110165;membrane#GO:0016020 dehydrogenase#PC00092;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000005953.3|UniProtKB=F6WFD9 F6WFD9 LOC100178291 PTHR10517:SF14 FOLATE RECEPTOR FOLATE RECEPTOR 1-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 membrane trafficking regulatory protein#PC00151 CIOIN|Ensembl=ENSCING00000011800.2|UniProtKB=F7A8M5 F7A8M5 PTHR45700:SF3 UBIQUITIN-PROTEIN LIGASE E3C UBIQUITIN-PROTEIN LIGASE E3B transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;protein polyubiquitination#GO:0000209;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 Ubiquitin proteasome pathway#P00060>E3#P01490 CIOIN|Ensembl=ENSCING00000005999.3|UniProtKB=F6V4L6 F6V4L6 LOC100182001 PTHR22951:SF5 CLATHRIN ASSEMBLY PROTEIN PHOSPHATIDYLINOSITOL-BINDING CLATHRIN ASSEMBLY PROTEIN LAP phosphatidylinositol bisphosphate binding#GO:1902936;small molecule binding#GO:0036094;phosphatidylinositol-4,5-bisphosphate binding#GO:0005546;binding#GO:0005488;protein binding#GO:0005515;clathrin binding#GO:0030276;lipid binding#GO:0008289;ion binding#GO:0043167;anion binding#GO:0043168;phosphatidylinositol binding#GO:0035091;phospholipid binding#GO:0005543;phosphatidylinositol phosphate binding#GO:1901981;SNARE binding#GO:0000149 localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;vesicle budding from membrane#GO:0006900;establishment of localization#GO:0051234;membrane organization#GO:0061024;organelle organization#GO:0006996;clathrin-dependent endocytosis#GO:0072583;transport#GO:0006810;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;vesicle organization#GO:0016050;cellular component organization#GO:0016043;receptor-mediated endocytosis#GO:0006898;cellular process#GO:0009987;import into cell#GO:0098657 cytoplasm#GO:0005737;clathrin-coated vesicle#GO:0030136;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular vesicle#GO:0097708;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;coated vesicle#GO:0030135;membrane#GO:0016020;vesicle#GO:0031982;clathrin-coated pit#GO:0005905;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 vesicle coat protein#PC00235 CIOIN|Ensembl=ENSCING00000009710.3|UniProtKB=F6U6J2 F6U6J2 LOC100185638 PTHR45712:SF26 AGAP008170-PA LRRNT DOMAIN-CONTAINING PROTEIN extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 CIOIN|Ensembl=ENSCING00000014941.2|UniProtKB=F6Y6P2 F6Y6P2 PTHR11036:SF127 SEMAPHORIN SEMAPHORIN-1A molecular function activator activity#GO:0140677;binding#GO:0005488;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;protein binding#GO:0005515;signaling receptor binding#GO:0005102 cellular developmental process#GO:0048869;regulation of cell motility#GO:2000145;regulation of locomotion#GO:0040012;stem cell development#GO:0048864;animal organ development#GO:0048513;neural crest cell development#GO:0014032;developmental process#GO:0032502;positive regulation of locomotion#GO:0040017;ameboidal-type cell migration#GO:0001667;cell motility#GO:0048870;cellular process#GO:0009987;tissue development#GO:0009888;mesenchymal cell differentiation#GO:0048762;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;cell development#GO:0048468;cell differentiation#GO:0030154;regulation of cell migration#GO:0030334;positive regulation of cell migration#GO:0030335;neural crest cell differentiation#GO:0014033;regulation of cellular process#GO:0050794;mesenchyme development#GO:0060485;anatomical structure development#GO:0048856;positive regulation of cell motility#GO:2000147;biological regulation#GO:0065007;stem cell differentiation#GO:0048863;neural crest cell migration#GO:0001755;cell migration#GO:0016477;positive regulation of biological process#GO:0048518 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 membrane-bound signaling molecule#PC00152;intercellular signal molecule#PC00207 CIOIN|Ensembl=ENSCING00000006726.3|UniProtKB=F6YLC8 F6YLC8 PTHR24416:SF539 TYROSINE-PROTEIN KINASE RECEPTOR RECEPTOR PROTEIN-TYROSINE KINASE signaling receptor activity#GO:0038023;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;molecular transducer activity#GO:0060089;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672;transmembrane signaling receptor activity#GO:0004888 signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;positive regulation of cellular metabolic process#GO:0031325;developmental process#GO:0032502;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;regulation of molecular function#GO:0065009;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;positive regulation of phosphorylation#GO:0042327;cellular response to stimulus#GO:0051716;positive regulation of catalytic activity#GO:0043085;multicellular organism development#GO:0007275;positive regulation of phosphorus metabolic process#GO:0010562;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphate metabolic process#GO:0045937;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;multicellular organismal process#GO:0032501;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 receptor complex#GO:0043235;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 CIOIN|Ensembl=ENSCING00000014878.2|UniProtKB=F6ZA35 F6ZA35 LOC100186832 PTHR10488:SF1 GLYCINE AMIDINOTRANSFERASE, MITOCHONDRIAL GLYCINE AMIDINOTRANSFERASE, MITOCHONDRIAL transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000006064.3|UniProtKB=F6ZZ65 F6ZZ65 PTHR20870:SF0 BARDET-BIEDL SYNDROME 1 PROTEIN BARDET-BIEDL SYNDROME 1 PROTEIN protein binding#GO:0005515;G protein-coupled receptor binding#GO:0001664;binding#GO:0005488;signaling receptor binding#GO:0005102 non-motile cilium assembly#GO:1905515;cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;cilium assembly#GO:0060271;cell projection organization#GO:0030030;macromolecule localization#GO:0033036;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031;protein localization#GO:0008104;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;protein localization to cilium#GO:0061512;organelle organization#GO:0006996;protein localization to organelle#GO:0033365;plasma membrane bounded cell projection assembly#GO:0120031 axoneme#GO:0005930;microtubule organizing center#GO:0005815;cytoplasmic region#GO:0099568;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;ciliary plasm#GO:0097014;plasma membrane bounded cell projection cytoplasm#GO:0032838;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cytoskeleton#GO:0005856;BBSome#GO:0034464;cilium#GO:0005929 CIOIN|Ensembl=ENSCING00000022819.1|UniProtKB=H2Y3V0 H2Y3V0 LOC100181651 PTHR13551:SF2 BRAIN PROTEIN I3 BRAIN PROTEIN I3 CIOIN|Ensembl=ENSCING00000018056.1|UniProtKB=F6U823 F6U823 PTHR10110:SF187 SODIUM/HYDROGEN EXCHANGER SODIUM_HYDROGEN EXCHANGER secondary active transmembrane transporter activity#GO:0015291;inorganic molecular entity transmembrane transporter activity#GO:0015318;antiporter activity#GO:0015297;transmembrane transporter activity#GO:0022857;potassium ion transmembrane transporter activity#GO:0015079;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;proton transmembrane transporter activity#GO:0015078;metal cation:proton antiporter activity#GO:0051139;active monoatomic ion transmembrane transporter activity#GO:0022853;monoatomic cation transmembrane transporter activity#GO:0008324;monoatomic ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;inorganic cation transmembrane transporter activity#GO:0022890;transporter activity#GO:0005215 regulation of intracellular pH#GO:0051453;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;homeostatic process#GO:0042592;inorganic ion transmembrane transport#GO:0098660;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;cellular process#GO:0009987;intracellular chemical homeostasis#GO:0055082;monoatomic ion homeostasis#GO:0050801;localization#GO:0051179;regulation of pH#GO:0006885;import across plasma membrane#GO:0098739;sodium ion transport#GO:0006814;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;intracellular monoatomic cation homeostasis#GO:0030003;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;monoatomic cation transport#GO:0006812;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion transport#GO:0006811;regulation of cellular pH#GO:0030641;import into cell#GO:0098657;monoatomic cation transmembrane transport#GO:0098655;sodium ion transmembrane transport#GO:0035725;potassium ion transport#GO:0006813 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000001593.3|UniProtKB=F6UM67 F6UM67 PTHR16047:SF7 RFWD3 PROTEIN E3 UBIQUITIN-PROTEIN LIGASE RFWD3 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000002986.3|UniProtKB=F6QYC9 F6QYC9 LOC100180564 PTHR23309:SF49 3-HYDROXYACYL-COA DEHYROGENASE PEROXISOMAL BIFUNCTIONAL ENZYME oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;lipid oxidation#GO:0034440;cellular metabolic process#GO:0044237;lipid catabolic process#GO:0016042;lipid modification#GO:0030258;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;fatty acid catabolic process#GO:0009062;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;fatty acid metabolic process#GO:0006631;small molecule catabolic process#GO:0044282;fatty acid beta-oxidation#GO:0006635;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;cellular lipid metabolic process#GO:0044255;cellular lipid catabolic process#GO:0044242;carboxylic acid metabolic process#GO:0019752;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;monocarboxylic acid catabolic process#GO:0072329 dehydrogenase#PC00092;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000010918.3|UniProtKB=F6TL19 F6TL19 PTHR10242:SF2 8-OXOGUANINE DNA GLYCOSYLASE N-GLYCOSYLASE_DNA LYASE DNA metabolism protein#PC00009 CIOIN|Ensembl=ENSCING00000000953.3|UniProtKB=F6VD64 F6VD64 LOC100181391 PTHR13477:SF0 MITOCHONDRIAL 39S RIBOSOMAL PROTEIN L49 LARGE RIBOSOMAL SUBUNIT PROTEIN ML49 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;mitochondrial large ribosomal subunit#GO:0005762;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;mitochondrial ribosome#GO:0005761;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;ribosomal subunit#GO:0044391;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;organellar ribosome#GO:0000313;protein-containing complex#GO:0032991;large ribosomal subunit#GO:0015934;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;ribosome#GO:0005840;mitochondrial protein-containing complex#GO:0098798 ribosomal protein#PC00202;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000018584.1|UniProtKB=F6Y4T2 F6Y4T2 PTHR32261:SF1 CALCIUM HOMEOSTASIS MODULATOR PROTEIN CALCIUM HOMEOSTASIS MODULATOR PROTEIN monoatomic cation channel activity#GO:0005261;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;transporter activity#GO:0005215 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 transporter#PC00227;voltage-gated ion channel#PC00241 CIOIN|Ensembl=ENSCING00000000220.3|UniProtKB=F6U3N6 F6U3N6 LOC100184731 PTHR24221:SF636 ATP-BINDING CASSETTE SUB-FAMILY B BILE SALT EXPORT PUMP transmembrane transporter activity#GO:0022857;primary active transmembrane transporter activity#GO:0015399;ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 localization#GO:0051179;cellular process#GO:0009987;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810 plasma membrane region#GO:0098590;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;apical part of cell#GO:0045177;plasma membrane#GO:0005886;apical plasma membrane#GO:0016324 ATP-binding cassette (ABC) transporter#PC00003;transporter#PC00227 CIOIN|Ensembl=ENSCING00000004780.3|UniProtKB=F6PLR0 F6PLR0 gnrh1 PTHR10522:SF5 GONADOLIBERIN PREPROGONADOTROPIN-RELEASING HORMONE 2 peptide hormone#PC00179 CIOIN|Ensembl=ENSCING00000009574.3|UniProtKB=F6TJN1 F6TJN1 PTHR46439:SF1 CYSTEINE-RICH MOTOR NEURON 1 PROTEIN CYSTEINE-RICH MOTOR NEURON 1 PROTEIN cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 CIOIN|Ensembl=ENSCING00000024719.1|UniProtKB=H2XX23 H2XX23 PTHR31661:SF1 SIMILAR TO CDNA SEQUENCE BC052040 CDAN1-INTERACTING NUCLEASE 1 CIOIN|Ensembl=ENSCING00000006592.3|UniProtKB=F6QQM7 F6QQM7 LOC100180875 PTHR11132:SF250 SOLUTE CARRIER FAMILY 35 SOLUTE CARRIER FAMILY 35 MEMBER E3 carbohydrate derivative transmembrane transporter activity#GO:1901505;secondary active transmembrane transporter activity#GO:0015291;antiporter activity#GO:0015297;transmembrane transporter activity#GO:0022857;nucleobase-containing compound transmembrane transporter activity#GO:0015932;nucleotide-sugar transmembrane transporter activity#GO:0005338;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215 localization#GO:0051179;cellular process#GO:0009987;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000012283.2|UniProtKB=F7BEP5 F7BEP5 LOC104265750 PTHR13126:SF0 CHAPERONE ATP11 ATP SYNTHASE MITOCHONDRIAL F1 COMPLEX ASSEMBLY FACTOR 1 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;protein-containing complex assembly#GO:0065003;mitochondrial proton-transporting ATP synthase complex assembly#GO:0033615;cellular component organization#GO:0016043;mitochondrion organization#GO:0007005;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chaperone#PC00072 CIOIN|Ensembl=ENSCING00000015910.2|UniProtKB=F6UFD0 F6UFD0 LOC100185111 PTHR46469:SF1 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 8 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 8 cellular aromatic compound metabolic process#GO:0006725;DNA-templated transcription#GO:0006351;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;RNA biosynthetic process#GO:0032774;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;transcription initiation at RNA polymerase II promoter#GO:0006367;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nucleobase-containing compound biosynthetic process#GO:0034654;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;DNA-templated transcription initiation#GO:0006352;aromatic compound biosynthetic process#GO:0019438;transcription by RNA polymerase II#GO:0006366;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;DNA-directed RNA polymerase complex#GO:0000428;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;transcription factor TFIID complex#GO:0005669;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695;RNA polymerase II, holoenzyme#GO:0016591;RNA polymerase complex#GO:0030880;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 General transcription by RNA polymerase I#P00022>TAF-IA#P00651;General transcription by RNA polymerase I#P00022>SL1 complex#P00653;General transcription by RNA polymerase I#P00022>TAF-IB#P00650;General transcription regulation#P00023>TBP-associated factors#P00658;Transcription regulation by bZIP transcription factor#P00055>TBP-associated factors#P01385;General transcription by RNA polymerase I#P00022>TAF-IC#P00649 CIOIN|Ensembl=ENSCING00000000198.3|UniProtKB=F6WF86 F6WF86 PTHR23255:SF104 TRANSFORMING GROWTH FACTOR-BETA RECEPTOR TYPE I AND II TGF-BETA RECEPTOR TYPE-2-LIKE ISOFORM X1 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular response to endogenous stimulus#GO:0071495;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;response to growth factor#GO:0070848;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;response to stimulus#GO:0050896;response to endogenous stimulus#GO:0009719;cellular response to growth factor stimulus#GO:0071363;nitrogen compound metabolic process#GO:0006807;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 receptor complex#GO:0043235;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 serine/threonine protein kinase receptor#PC00205 CIOIN|Ensembl=ENSCING00000020808.1|UniProtKB=H2XR96 H2XR96 LOC100183634 PTHR11360:SF284 MONOCARBOXYLATE TRANSPORTER EG:103B4.3 PROTEIN-RELATED transporter#PC00227 CIOIN|Ensembl=ENSCING00000006813.3|UniProtKB=F6TZX4 F6TZX4 LOC100178584 PTHR24031:SF25 RNA HELICASE ATP-DEPENDENT RNA HELICASE DDX46-RELATED cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA helicase#PC00032 CIOIN|Ensembl=ENSCING00000009645.3|UniProtKB=F6XHU3 F6XHU3 PTHR46799:SF1 HOMEOBOX PROTEIN UNC-4 HOMOLOG HOMEOBOX PROTEIN UNC-4 HOMOLOG sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of biosynthetic process#GO:0009889;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 CIOIN|Ensembl=ENSCING00000011945.2|UniProtKB=F6VA41 F6VA41 PTHR24126:SF14 ANKYRIN REPEAT, PH AND SEC7 DOMAIN CONTAINING PROTEIN SECG-RELATED ANK_REP_REGION DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000009881.3|UniProtKB=F6RB18 F6RB18 PTHR22775:SF48 SORTING NEXIN SORTING NEXIN-25 lipid binding#GO:0008289;phosphatidylinositol binding#GO:0035091;phospholipid binding#GO:0005543;binding#GO:0005488 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000009809.3|UniProtKB=F6Y677 F6Y677 PTHR44177:SF1 TETRATRICOPEPTIDE REPEAT PROTEIN 8 TETRATRICOPEPTIDE REPEAT PROTEIN 8 organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;non-motile cilium assembly#GO:1905515;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cell projection organization#GO:0030030;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031 microtubule organizing center#GO:0005815;non-motile cilium#GO:0097730;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;ciliary basal body#GO:0036064;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cytoskeleton#GO:0005856;BBSome#GO:0034464;cilium#GO:0005929 CIOIN|Ensembl=ENSCING00000020146.1|UniProtKB=H2Y0F9 H2Y0F9 PTHR28680:SF1 CENTROMERE PROTEIN X CENTROMERE PROTEIN X cellular aromatic compound metabolic process#GO:0006725;nuclear division#GO:0000280;cell cycle process#GO:0022402;nucleobase-containing compound metabolic process#GO:0006139;reciprocal homologous recombination#GO:0140527;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;meiotic cell cycle process#GO:1903046;DNA-templated DNA replication#GO:0006261;meiosis I cell cycle process#GO:0061982;reproductive process#GO:0022414;reciprocal meiotic recombination#GO:0007131;replication fork processing#GO:0031297;meiosis I#GO:0007127;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;meiotic cell cycle#GO:0051321;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;DNA recombination#GO:0006310;resolution of meiotic recombination intermediates#GO:0000712;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;reproduction#GO:0000003;meiotic nuclear division#GO:0140013;organelle organization#GO:0006996;sexual reproduction#GO:0019953;cell cycle#GO:0007049;organelle fission#GO:0048285;homologous recombination#GO:0035825;DNA replication#GO:0006260;DNA metabolic process#GO:0006259 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000004405.3|UniProtKB=F7AB40 F7AB40 PTHR19300:SF57 BETA-1,4-GALACTOSYLTRANSFERASE BETA-1,4-N-ACETYLGALACTOSAMINYLTRANSFERASE galactosyltransferase activity#GO:0008378;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 glycosylation#GO:0070085;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000007663.3|UniProtKB=F6T7M7 F6T7M7 PTHR13265:SF0 THO COMPLEX SUBUNIT 1 HPR1 mRNA export from nucleus#GO:0006406;cellular localization#GO:0051641;macromolecule biosynthetic process#GO:0009059;macromolecule localization#GO:0033036;establishment of RNA localization#GO:0051236;macromolecule metabolic process#GO:0043170;transport#GO:0006810;nucleic acid transport#GO:0050657;nitrogen compound transport#GO:0071705;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;mRNA transport#GO:0051028;RNA localization#GO:0006403;localization#GO:0051179;organic substance transport#GO:0071702;nuclear export#GO:0051168;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;RNA transport#GO:0050658;nucleobase-containing compound transport#GO:0015931;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;nuclear transport#GO:0051169;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;THO complex#GO:0000347;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;transcription export complex#GO:0000346;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000003765.3|UniProtKB=F6TIJ9 F6TIJ9 PTHR10127:SF861 DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING DORSAL-VENTRAL PATTERNING PROTEIN TOLLOID-RELATED hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 SCW signaling pathway#P06216>TLD#P06327;DPP-SCW signaling pathway#P06212>TLD#P06264;TGF-beta signaling pathway#P00052>TGFbeta#P01286;DPP signaling pathway#P06213>TLD#P06283;BMP/activin signaling pathway-drosophila#P06211>TLD#P06249 CIOIN|Ensembl=ENSCING00000022072.1|UniProtKB=H2XYH4 H2XYH4 PTHR13132:SF29 ALPHA- 1,6 -FUCOSYLTRANSFERASE ALPHA-(1,6)-FUCOSYLTRANSFERASE transferase activity#GO:0016740;fucosyltransferase activity#GO:0008417;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein glycosylation#GO:0006486;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein N-linked glycosylation#GO:0006487;protein metabolic process#GO:0019538;glycosylation#GO:0070085;glycoprotein metabolic process#GO:0009100;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 glycosyltransferase#PC00111 Notch signaling pathway#P00045>Neurotic#P01115 CIOIN|Ensembl=ENSCING00000002531.3|UniProtKB=F6XRZ3 F6XRZ3 LOC100184660 PTHR16146:SF46 INTELECTIN INTELECTIN-1A-RELATED CIOIN|Ensembl=ENSCING00000011307.2|UniProtKB=F6XJX5 F6XJX5 PTHR45998:SF2 SERINE/THREONINE-PROTEIN KINASE 16 SERINE_THREONINE-PROTEIN KINASE 16 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 CIOIN|Ensembl=ENSCING00000012537.2|UniProtKB=F7AUT5 F7AUT5 PTHR11211:SF40 IROQUOIS-CLASS HOMEODOMAIN PROTEIN IRX MIRROR, ISOFORM C sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;neurogenesis#GO:0022008;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;multicellular organism development#GO:0007275;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell development#GO:0048468;system development#GO:0048731;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;neuron differentiation#GO:0030182;multicellular organismal process#GO:0032501;regulation of macromolecule biosynthetic process#GO:0010556;generation of neurons#GO:0048699;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 CIOIN|Ensembl=ENSCING00000023825.1|UniProtKB=H2XND0 H2XND0 PTHR24372:SF77 GLYCOPROTEIN HORMONE RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 response to organic substance#GO:0010033;positive regulation of adenylate cyclase activity#GO:0045762;regulation of lyase activity#GO:0051339;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;cellular response to stimulus#GO:0051716;regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;cellular response to endogenous stimulus#GO:0071495;cellular response to chemical stimulus#GO:0070887;positive regulation of catalytic activity#GO:0043085;cellular response to organic substance#GO:0071310;regulation of cyclase activity#GO:0031279;positive regulation of molecular function#GO:0044093;cell communication#GO:0007154;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;positive regulation of cyclase activity#GO:0031281;hormone-mediated signaling pathway#GO:0009755;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to endogenous stimulus#GO:0009719;response to hormone#GO:0009725;cellular response to hormone stimulus#GO:0032870;response to chemical#GO:0042221;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of lyase activity#GO:0051349;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 CIOIN|Ensembl=ENSCING00000011437.2|UniProtKB=F6Y5N8 F6Y5N8 PTHR21210:SF0 TRNA (URACIL-O(2)-)-METHYLTRANSFERASE-RELATED TRNA (URACIL-O(2)-)-METHYLTRANSFERASE-RELATED tRNA methyltransferase activity#GO:0008175;catalytic activity, acting on RNA#GO:0140098;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;RNA methyltransferase activity#GO:0008173 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA modification#GO:0009451;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;tRNA modification#GO:0006400;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;macromolecule methylation#GO:0043414;tRNA methylation#GO:0030488;organic cyclic compound metabolic process#GO:1901360;methylation#GO:0032259;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;RNA methylation#GO:0001510;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 CIOIN|Ensembl=ENSCING00000012887.2|UniProtKB=F6R1B9 F6R1B9 LOC100176880 PTHR15651:SF7 ARMADILLO REPEAT-CONTAINING PROTEIN 8 ARMADILLO REPEAT-CONTAINING PROTEIN 8 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;transferase complex#GO:1990234 CIOIN|Ensembl=ENSCING00000011746.1|UniProtKB=F6TAI3 F6TAI3 PTHR34400:SF4 FAMILY NOT NAMED MEMBRANE PROTEIN CIOIN|Ensembl=ENSCING00000020904.1|UniProtKB=H2XT03 H2XT03 PTHR10924:SF6 MAJOR FACILITATOR SUPERFAMILY PROTEIN-RELATED SOLUTE CARRIER FAMILY 49 MEMBER A3 cellular anatomical entity#GO:0110165;membrane#GO:0016020 secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000009408.3|UniProtKB=F6U9J6 F6U9J6 LOC100185377 PTHR24300:SF417 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 508B1-RELATED oxygenase#PC00177;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000014589.2|UniProtKB=F6SYN7 F6SYN7 LOC100186963 PTHR24228:SF72 B2 BRADYKININ RECEPTOR/ANGIOTENSIN II RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 G-protein coupled receptor#PC00021 CIOIN|Ensembl=ENSCING00000003531.3|UniProtKB=F7AZ43 F7AZ43 PTHR31859:SF1 TETRATRICOPEPTIDE REPEAT PROTEIN 39 FAMILY MEMBER TETRATRICOPEPTIDE REPEAT PROTEIN 39C CIOIN|Ensembl=ENSCING00000003326.3|UniProtKB=F6SNL0 F6SNL0 LOC100177507 PTHR11994:SF8 60S RIBOSOMAL PROTEIN L11-RELATED 60S RIBOSOMAL PROTEIN L11 structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;structural molecule activity#GO:0005198;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic large ribosomal subunit#GO:0022625;large ribosomal subunit#GO:0015934;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;ribosomal subunit#GO:0044391 ribosomal protein#PC00202;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000018450.1|UniProtKB=H2XW44 H2XW44 LOC100177853 PTHR12113:SF6 DICKKOPF3-LIKE 3 DICKKOPF N-TERMINAL CYSTEINE-RICH DOMAIN-CONTAINING PROTEIN signaling receptor regulator activity#GO:0030545;protein binding#GO:0005515;molecular function inhibitor activity#GO:0140678;binding#GO:0005488;molecular function regulator activity#GO:0098772;signaling receptor binding#GO:0005102 regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;negative regulation of response to stimulus#GO:0048585;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;regulation of canonical Wnt signaling pathway#GO:0060828;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;regulation of Wnt signaling pathway#GO:0030111;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of canonical Wnt signaling pathway#GO:0090090;negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 membrane trafficking regulatory protein#PC00151 CIOIN|Ensembl=ENSCING00000008839.3|UniProtKB=A0A1W2WK21 A0A1W2WK21 PTHR22968:SF24 PROTEIN KINASE C, MU SERINE_THREONINE-PROTEIN KINASE transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;signaling#GO:0023052 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 VEGF signaling pathway#P00056>PKC#P01425;Angiogenesis#P00005>PKC#P00219;EGF receptor signaling pathway#P00018>PKC#P00565 CIOIN|Ensembl=ENSCING00000012078.2|UniProtKB=F6YH71 F6YH71 PTHR10869:SF244 PROLYL 4-HYDROXYLASE ALPHA SUBUNIT PROLYL 4-HYDROXYLASE SUBUNIT ALPHA-2 2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;dioxygenase activity#GO:0051213 oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular modified amino acid metabolic process#GO:0006575;protein hydroxylation#GO:0018126;alpha-amino acid metabolic process#GO:1901605;protein metabolic process#GO:0019538;carboxylic acid metabolic process#GO:0019752;L-amino acid metabolic process#GO:0170033;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000021669.1|UniProtKB=F6UWB9 F6UWB9 PTHR12867:SF6 GLYCOSYL TRANSFERASE-RELATED N-ACETYLGLUCOSAMINYLDIPHOSPHODOLICHOL N-ACETYLGLUCOSAMINYLTRANSFERASE transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000019110.1|UniProtKB=H2XL27 H2XL27 nr41_42_43 PTHR24085:SF4 NUCLEAR HORMONE RECEPTOR NUCLEAR HORMONE RECEPTOR HR38-RELATED cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;double-stranded DNA binding#GO:0003690;transcription factor binding#GO:0008134;DNA-binding transcription factor binding#GO:0140297;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;nuclear receptor binding#GO:0016922;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;protein binding#GO:0005515;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;response to peptide hormone#GO:0043434;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;cellular response to nitrogen compound#GO:1901699;regulation of biological process#GO:0050789;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;cellular response to hormone stimulus#GO:0032870;response to peptide#GO:1901652;regulation of biosynthetic process#GO:0009889;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;cellular response to endogenous stimulus#GO:0071495;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;cellular response to organic substance#GO:0071310;regulation of DNA-templated transcription#GO:0006355;response to organonitrogen compound#GO:0010243;cellular response to peptide#GO:1901653;cellular response to peptide hormone stimulus#GO:0071375;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to hormone#GO:0009725;regulation of cellular biosynthetic process#GO:0031326;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;cellular response to organonitrogen compound#GO:0071417;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C4 zinc finger nuclear receptor#PC00169;zinc finger transcription factor#PC00244 CIOIN|Ensembl=ENSCING00000024033.1|UniProtKB=H2XUB4 H2XUB4 PTHR34629:SF1 PROLINE-RICH EXTENSIN-LIKE PROTEIN EPR1 PROLINE-RICH EXTENSIN-LIKE PROTEIN EPR1 CIOIN|Ensembl=ENSCING00000005348.2|UniProtKB=F7ALS7 F7ALS7 LOC100183530 PTHR10706:SF160 F-BOX FAMILY PROTEIN F-BOX ONLY PROTEIN 39 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 SCF ubiquitin ligase complex#GO:0019005;intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;cullin-RING ubiquitin ligase complex#GO:0031461;transferase complex#GO:1990234 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000022595.1|UniProtKB=H2XX94 H2XX94 PTHR36978:SF4 P-LOOP CONTAINING NUCLEOTIDE TRIPHOSPHATE HYDROLASE P-LOOP CONTAINING NUCLEOSIDE TRIPHOSPHATE HYDROLASE PROTEIN metabolite interconversion enzyme#PC00262;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000005261.3|UniProtKB=F6V9P3 F6V9P3 PTHR31551:SF1 PRE-MRNA-SPLICING FACTOR CWF18 COILED-COIL DOMAIN-CONTAINING PROTEIN 12 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;U2-type spliceosomal complex#GO:0005684;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;post-mRNA release spliceosomal complex#GO:0071014;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622 RNA splicing factor#PC00148;RNA processing factor#PC00147;RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000009439.3|UniProtKB=F6TKR9 F6TKR9 LOC100180278 PTHR43401:SF2 L-THREONINE 3-DEHYDROGENASE L-THREONINE 3-DEHYDROGENASE dehydrogenase#PC00092;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000018515.1|UniProtKB=F7AX69 F7AX69 PTHR11984:SF53 CONNEXIN GAP JUNCTION PROTEIN wide pore channel activity#GO:0022829;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;channel activity#GO:0015267 biological regulation#GO:0065007;regulation of biological process#GO:0050789;cell communication#GO:0007154;cellular process#GO:0009987;cell-cell signaling#GO:0007267;signaling#GO:0023052 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 cell junction protein#PC00070;gap junction#PC00105 CIOIN|Ensembl=ENSCING00000001928.3|UniProtKB=A0A1W2W8Q4 A0A1W2W8Q4 LOC100179818 PTHR19315:SF9 ER MEMBRANE PROTEIN COMPLEX SUBUNIT 4 ER MEMBRANE PROTEIN COMPLEX SUBUNIT 4 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein folding#GO:0006457;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane protein complex#GO:0098796;endoplasmic reticulum protein-containing complex#GO:0140534;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;EMC complex#GO:0072546;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 CIOIN|Ensembl=ENSCING00000019233.1|UniProtKB=H2XT07 H2XT07 LOC100181541 PTHR23320:SF165 MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MS4A -RELATED MARVEL DOMAIN-CONTAINING PROTEIN transporter#PC00227 CIOIN|Ensembl=ENSCING00000008638.3|UniProtKB=F7AGX6 F7AGX6 PTHR36978:SF4 P-LOOP CONTAINING NUCLEOTIDE TRIPHOSPHATE HYDROLASE P-LOOP CONTAINING NUCLEOSIDE TRIPHOSPHATE HYDROLASE PROTEIN metabolite interconversion enzyme#PC00262;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000020400.1|UniProtKB=H2Y0K3 H2Y0K3 LOC100186953 PTHR48176:SF1 DDRGK DOMAIN-CONTAINING PROTEIN 1 DDRGK DOMAIN-CONTAINING PROTEIN 1 enzyme binding#GO:0019899;protein binding#GO:0005515;binding#GO:0005488;ubiquitin-like protein ligase binding#GO:0044389 CIOIN|Ensembl=ENSCING00000018710.1|UniProtKB=H2XM75 H2XM75 PTHR10036:SF3 CD59 GLYCOPROTEIN PROTEIN SLEEPLESS-RELATED CIOIN|Ensembl=ENSCING00000002517.3|UniProtKB=F6WI19 F6WI19 LOC100181145 PTHR19818:SF139 ZINC FINGER PROTEIN ZIC AND GLI PAIR-RULE PROTEIN ODD-PAIRED sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 CIOIN|Ensembl=ENSCING00000005187.3|UniProtKB=F7B7H5 F7B7H5 PTHR11465:SF9 CATALASE CATALASE antioxidant activity#GO:0016209;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;tetrapyrrole binding#GO:0046906;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;oxidoreductase activity#GO:0016491;heme binding#GO:0020037 response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;response to oxygen-containing compound#GO:1901700;catabolic process#GO:0009056;cellular metabolic process#GO:0044237;response to reactive oxygen species#GO:0000302;response to oxidative stress#GO:0006979;cellular process#GO:0009987;cellular catabolic process#GO:0044248;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 peroxidase#PC00180;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000013793.2|UniProtKB=F6RE18 F6RE18 PTHR11693:SF22 ATP SYNTHASE GAMMA CHAIN ATP SYNTHASE SUBUNIT GAMMA, MITOCHONDRIAL monoatomic cation channel activity#GO:0005261;ligase activity#GO:0016874;inorganic molecular entity transmembrane transporter activity#GO:0015318;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;catalytic activity#GO:0003824;proton transmembrane transporter activity#GO:0015078;proton channel activity#GO:0015252;proton-transporting ATP synthase activity, rotational mechanism#GO:0046933;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;inorganic cation transmembrane transporter activity#GO:0022890;channel activity#GO:0015267;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 cellular aromatic compound metabolic process#GO:0006725;ribonucleoside triphosphate metabolic process#GO:0009199;nucleoside triphosphate metabolic process#GO:0009141;carbohydrate derivative metabolic process#GO:1901135;ATP biosynthetic process#GO:0006754;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ATP metabolic process#GO:0046034;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;purine nucleoside triphosphate biosynthetic process#GO:0009145;heterocycle metabolic process#GO:0046483;purine ribonucleoside triphosphate metabolic process#GO:0009205;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;ribonucleoside triphosphate biosynthetic process#GO:0009201;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;proton motive force-driven ATP synthesis#GO:0015986;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;nucleoside triphosphate biosynthetic process#GO:0009142;organophosphate metabolic process#GO:0019637;purine nucleoside triphosphate metabolic process#GO:0009144;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 ATP synthase#PC00002;primary active transporter#PC00068;transporter#PC00227 ATP synthesis#P02721>F1 gamma#P02796 CIOIN|Ensembl=ENSCING00000008385.3|UniProtKB=F6YEI6 F6YEI6 LOC100179672 PTHR43289:SF6 MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 20-RELATED SERINE_THREONINE-PROTEIN KINASE NEKL-3 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;peptidyl-amino acid modification#GO:0018193;cellular process#GO:0009987;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;nitrogen compound metabolic process#GO:0006807;peptidyl-serine modification#GO:0018209;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000012430.2|UniProtKB=F6VID6 F6VID6 PTHR12480:SF41 ARGININE DEMETHYLASE AND LYSYL-HYDROXYLASE JMJD JMJC DOMAIN-CONTAINING PROTEIN sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;dioxygenase activity#GO:0051213;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity#GO:0016491 positive regulation of gene expression#GO:0010628;positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of protein metabolic process#GO:0051246;regulation of amide metabolic process#GO:0034248;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;protein modification process#GO:0036211;regulation of cellular component organization#GO:0051128;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;protein hydroxylation#GO:0018126;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;positive regulation of biological process#GO:0048518;positive regulation of translation#GO:0045727;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;regulation of protein-containing complex disassembly#GO:0043244;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;positive regulation of protein metabolic process#GO:0051247;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;post-transcriptional regulation of gene expression#GO:0010608;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;regulation of translation#GO:0006417;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000003368.4|UniProtKB=F7BA03 F7BA03 PTHR48075:SF1 3-HYDROXYACYL-COA DEHYDROGENASE FAMILY PROTEIN LAMBDA-CRYSTALLIN HOMOLOG oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 dehydrogenase#PC00092;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000008075.3|UniProtKB=F6Z768 F6Z768 PTHR22916:SF3 GLYCOSYLTRANSFERASE UDP-GLCNAC:BETAGAL BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE-LIKE PROTEIN 1 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000013688.2|UniProtKB=F6QY76 F6QY76 LOC104266815 PTHR33887:SF5 PB1 DOMAIN-CONTAINING PROTEIN PB1 DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000008397.3|UniProtKB=F6X229 F6X229 PTHR42861:SF127 CALCIUM-TRANSPORTING ATPASE CALCIUM-TRANSPORTING ATPASE SARCOPLASMIC_ENDOPLASMIC RETICULUM TYPE calcium ion transmembrane transporter activity#GO:0015085;inorganic molecular entity transmembrane transporter activity#GO:0015318;transmembrane transporter activity#GO:0022857;primary active transmembrane transporter activity#GO:0015399;ATP-dependent activity#GO:0140657;metal ion transmembrane transporter activity#GO:0046873;active monoatomic ion transmembrane transporter activity#GO:0022853;P-type ion transporter activity#GO:0015662;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;ATPase-coupled transmembrane transporter activity#GO:0042626;monoatomic cation transmembrane transporter activity#GO:0008324;monoatomic ion transmembrane transporter activity#GO:0015075;inorganic cation transmembrane transporter activity#GO:0022890;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;calcium ion transmembrane transport#GO:0070588;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;homeostatic process#GO:0042592;monoatomic cation homeostasis#GO:0055080;inorganic ion transmembrane transport#GO:0098660;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;cellular process#GO:0009987;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;calcium ion transport#GO:0006816;monoatomic ion homeostasis#GO:0050801;localization#GO:0051179;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation transport#GO:0006812;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655 cellular anatomical entity#GO:0110165;membrane#GO:0016020 primary active transporter#PC00068;transporter#PC00227 CIOIN|Ensembl=ENSCING00000008580.3|UniProtKB=F6ZUV7 F6ZUV7 PTHR10656:SF70 CELL FATE DETERMINING PROTEIN MAB21-RELATED PROTEIN MAB-21-RELATED transferase#PC00220;nucleotidyltransferase#PC00174;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000011947.2|UniProtKB=F6SAX8 F6SAX8 LOC100184468 PTHR11843:SF0 40S RIBOSOMAL PROTEIN S12 SMALL RIBOSOMAL SUBUNIT PROTEIN ES12 cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;translation#GO:0006412;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;cellular component organization or biogenesis#GO:0071840;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;ribosomal small subunit biogenesis#GO:0042274;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 ribosomal protein#PC00202;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000007015.3|UniProtKB=F7AEK6 F7AEK6 PTHR22726:SF1 METALLOENDOPEPTIDASE OMA1 METALLOENDOPEPTIDASE OMA1, MITOCHONDRIAL hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;catabolic process#GO:0009056;organonitrogen compound catabolic process#GO:1901565;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;membrane#GO:0016020 metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000006448.3|UniProtKB=F6QKM5 F6QKM5 PTHR22959:SF0 PYM PROTEIN PARTNER OF Y14 AND MAGO nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;cellular component disassembly#GO:0022411;protein-containing complex disassembly#GO:0032984;cellular process#GO:0009987;protein-containing complex organization#GO:0043933 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000015610.2|UniProtKB=F6ZK97 F6ZK97 PTHR12733:SF3 MITOCHONDRIAL ATP SYNTHASE B CHAIN ATP SYNTHASE F(0) COMPLEX SUBUNIT B1, MITOCHONDRIAL ATP synthase#PC00002;primary active transporter#PC00068;transporter#PC00227 CIOIN|Ensembl=ENSCING00000014446.2|UniProtKB=F6YB59 F6YB59 PTHR12547:SF18 CCCH ZINC FINGER/TIS11-RELATED PROTEIN TIS11 RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000016235.2|UniProtKB=F6Z8A3 F6Z8A3 LOC100176529 PTHR43289:SF33 MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 20-RELATED SERINE_THREONINE KINASE 31 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;peptidyl-amino acid modification#GO:0018193;cellular process#GO:0009987;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;nitrogen compound metabolic process#GO:0006807;peptidyl-serine modification#GO:0018209;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000007504.3|UniProtKB=F6X753 F6X753 PTHR48041:SF116 ABC TRANSPORTER G FAMILY MEMBER 28 PROTEIN BROWN transmembrane transporter activity#GO:0022857;primary active transmembrane transporter activity#GO:0015399;ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 localization#GO:0051179;cellular process#GO:0009987;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 ATP-binding cassette (ABC) transporter#PC00003;transporter#PC00227 CIOIN|Ensembl=ENSCING00000022941.1|UniProtKB=H2XTS9 H2XTS9 PTHR45720:SF10 CHLORIDE CHANNEL PROTEIN 2 CHLORIDE CHANNEL PROTEIN 2 voltage-gated monoatomic ion channel activity#GO:0005244;inorganic molecular entity transmembrane transporter activity#GO:0015318;chloride channel activity#GO:0005254;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;voltage-gated channel activity#GO:0022832;gated channel activity#GO:0022836;chloride transmembrane transporter activity#GO:0015108;monoatomic anion transmembrane transporter activity#GO:0008509;inorganic anion transmembrane transporter activity#GO:0015103;transporter activity#GO:0005215;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267 localization#GO:0051179;chloride transport#GO:0006821;monoatomic ion transport#GO:0006811;establishment of localization#GO:0051234;inorganic anion transport#GO:0015698;monoatomic anion transport#GO:0006820;transport#GO:0006810 ion channel#PC00133;transporter#PC00227 CIOIN|Ensembl=ENSCING00000014225.2|UniProtKB=F6Y0S7 F6Y0S7 PTHR24416:SF620 TYROSINE-PROTEIN KINASE RECEPTOR TYROSINE-PROTEIN KINASE RECEPTOR TORSO signaling receptor activity#GO:0038023;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;molecular transducer activity#GO:0060089;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672;transmembrane signaling receptor activity#GO:0004888 signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;positive regulation of cellular metabolic process#GO:0031325;developmental process#GO:0032502;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;regulation of molecular function#GO:0065009;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;positive regulation of phosphorylation#GO:0042327;cellular response to stimulus#GO:0051716;positive regulation of catalytic activity#GO:0043085;multicellular organism development#GO:0007275;positive regulation of phosphorus metabolic process#GO:0010562;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphate metabolic process#GO:0045937;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;multicellular organismal process#GO:0032501;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 receptor complex#GO:0043235;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 CIOIN|Ensembl=ENSCING00000003272.3|UniProtKB=F6WN97 F6WN97 PTHR38537:SF8 JITTERBUG, ISOFORM N FILAMIN-A CIOIN|Ensembl=ENSCING00000003810.3|UniProtKB=F6ZTM3 F6ZTM3 LOC101242989 PTHR45817:SF4 LYSYL OXIDASE-LIKE-RELATED LYSYL OXIDASE-LIKE-RELATED catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 oxidase#PC00175;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000000047.3|UniProtKB=F6ZIX0 F6ZIX0 PTHR12400:SF21 INOSITOL POLYPHOSPHATE KINASE KINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301 organic hydroxy compound metabolic process#GO:1901615;organophosphate biosynthetic process#GO:0090407;alcohol biosynthetic process#GO:0046165;cellular metabolic process#GO:0044237;alcohol metabolic process#GO:0006066;organic hydroxy compound biosynthetic process#GO:1901617;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;organophosphate metabolic process#GO:0019637;small molecule biosynthetic process#GO:0044283;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 kinase#PC00137 CIOIN|Ensembl=ENSCING00000018836.1|UniProtKB=H2XXM9 H2XXM9 LOC100184668 PTHR10663:SF372 GUANYL-NUCLEOTIDE EXCHANGE FACTOR F-BOX ONLY PROTEIN 8 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 CIOIN|Ensembl=ENSCING00000008816.3|UniProtKB=F7BJA7 F7BJA7 LOC100184003 PTHR23316:SF28 IMPORTIN ALPHA IMPORTIN SUBUNIT ALPHA signal sequence binding#GO:0005048;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277 cellular localization#GO:0051641;NLS-bearing protein import into nucleus#GO:0006607;macromolecule localization#GO:0033036;transport#GO:0006810;protein localization to nucleus#GO:0034504;nitrogen compound transport#GO:0071705;establishment of protein localization to organelle#GO:0072594;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;protein import into nucleus#GO:0006606;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;protein localization to organelle#GO:0033365;nuclear transport#GO:0051169;import into nucleus#GO:0051170 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transporter#PC00227 CIOIN|Ensembl=ENSCING00000008020.3|UniProtKB=F6SSL3 F6SSL3 LOC100183164 PTHR12227:SF0 GLYCERATE KINASE GLYCERATE KINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;phosphorylation#GO:0016310;protein phosphorylation#GO:0006468;cellular process#GO:0009987;protein metabolic process#GO:0019538;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;carbohydrate kinase#PC00065 CIOIN|Ensembl=ENSCING00000005194.3|UniProtKB=F7B6X8 F7B6X8 PTHR11675:SF134 N-ACETYLGALACTOSAMINYLTRANSFERASE N-ACETYLGALACTOSAMINYLTRANSFERASE 4-RELATED transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;UDP-glycosyltransferase activity#GO:0008194 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;protein O-linked glycosylation#GO:0006493;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000017355.2|UniProtKB=F6XP80 F6XP80 PTHR24126:SF14 ANKYRIN REPEAT, PH AND SEC7 DOMAIN CONTAINING PROTEIN SECG-RELATED ANK_REP_REGION DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000008321.3|UniProtKB=Q1RL40 Q1RL40 Ci-ZF(RING)-55 PTHR12683:SF13 CDK-ACTIVATING KINASE ASSEMBLY FACTOR MAT1 CDK-ACTIVATING KINASE ASSEMBLY FACTOR MAT1 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;regulation of DNA-templated transcription#GO:0006355;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;response to stress#GO:0006950;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;cellular response to stress#GO:0033554;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;DNA metabolic process#GO:0006259 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;DNA-directed RNA polymerase complex#GO:0000428;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nucleoplasm#GO:0005654;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;serine/threonine protein kinase complex#GO:1902554;RNA polymerase II transcription regulator complex#GO:0090575;protein kinase complex#GO:1902911;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622;RNA polymerase II, holoenzyme#GO:0016591;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;transcription regulator complex#GO:0005667;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;transcription factor TFIIH holo complex#GO:0005675;nuclear protein-containing complex#GO:0140513 chaperone#PC00072 CIOIN|Ensembl=ENSCING00000006889.3|UniProtKB=F6YU08 F6YU08 PTHR24372:SF77 GLYCOPROTEIN HORMONE RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 response to organic substance#GO:0010033;positive regulation of adenylate cyclase activity#GO:0045762;regulation of lyase activity#GO:0051339;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;cellular response to stimulus#GO:0051716;regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;cellular response to endogenous stimulus#GO:0071495;cellular response to chemical stimulus#GO:0070887;positive regulation of catalytic activity#GO:0043085;cellular response to organic substance#GO:0071310;regulation of cyclase activity#GO:0031279;positive regulation of molecular function#GO:0044093;cell communication#GO:0007154;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;positive regulation of cyclase activity#GO:0031281;hormone-mediated signaling pathway#GO:0009755;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to endogenous stimulus#GO:0009719;response to hormone#GO:0009725;cellular response to hormone stimulus#GO:0032870;response to chemical#GO:0042221;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of lyase activity#GO:0051349;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 CIOIN|Ensembl=ENSCING00000018185.1|UniProtKB=A0A1W5B320 A0A1W5B320 LOC100180651 PTHR44086:SF10 THIOSULFATE SULFURTRANSFERASE RDL2, MITOCHONDRIAL-RELATED THIOSULFATE SULFURTRANSFERASE_RHODANESE-LIKE DOMAIN-CONTAINING PROTEIN 3 thiosulfate sulfurtransferase activity#GO:0004792;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824;sulfurtransferase activity#GO:0016783 transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000012738.2|UniProtKB=F7A9D9 F7A9D9 LOC100183193 PTHR23092:SF15 POLY(A) RNA POLYMERASE INACTIVE NON-CANONICAL POLY(A) RNA POLYMERASE PROTEIN TRF4-2-RELATED adenylyltransferase activity#GO:0070566;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;transferase activity#GO:0016740;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;nucleotidyltransferase activity#GO:0016779;transferase activity, transferring phosphorus-containing groups#GO:0016772;mRNA binding#GO:0003729 cellular aromatic compound metabolic process#GO:0006725;heterocycle catabolic process#GO:0046700;RNA metabolic process#GO:0016070;RNA processing#GO:0006396;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;cellular nitrogen compound catabolic process#GO:0044270;modification-dependent macromolecule catabolic process#GO:0043632;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;organic substance catabolic process#GO:1901575;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;macromolecule biosynthetic process#GO:0009059;RNA 3'-end processing#GO:0031123;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;organic cyclic compound catabolic process#GO:1901361;nucleobase-containing compound catabolic process#GO:0034655;polyadenylation-dependent ncRNA catabolic process#GO:0043634 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 mRNA polyadenylation factor#PC00146;RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000005717.3|UniProtKB=F6U302 F6U302 PTHR11304:SF29 EPHRIN EPHRIN protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 neuron projection guidance#GO:0097485;signal transduction#GO:0007165;neurogenesis#GO:0022008;cell projection organization#GO:0030030;developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cellular anatomical entity morphogenesis#GO:0032989;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;axon guidance#GO:0007411;anatomical structure morphogenesis#GO:0009653;neuron differentiation#GO:0030182;axonogenesis#GO:0007409;plasma membrane bounded cell projection morphogenesis#GO:0120039;signaling#GO:0023052;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;multicellular organism development#GO:0007275;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;cell communication#GO:0007154;cellular process#GO:0009987;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;neuron projection development#GO:0031175;axon development#GO:0061564;enzyme-linked receptor protein signaling pathway#GO:0007167;cell morphogenesis involved in neuron differentiation#GO:0048667;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 membrane-bound signaling molecule#PC00152;intercellular signal molecule#PC00207 CIOIN|Ensembl=ENSCING00000024403.1|UniProtKB=H2XUW4 H2XUW4 PTHR24068:SF128 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 H ubiquitin-like protein conjugating enzyme activity#GO:0061650;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin conjugating enzyme activity#GO:0061631;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;protein polyubiquitination#GO:0000209;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 Ubiquitin proteasome pathway#P00060>E3#P01490;Ubiquitin proteasome pathway#P00060>E2#P01491 CIOIN|Ensembl=ENSCING00000021238.1|UniProtKB=H2Y1F2 H2Y1F2 PTHR31428:SF6 RGM DOMAIN FAMILY MEMBER DRAG-1 REPULSIVE GUIDANCE MOLECULE B HOMOLOG DRAG-1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular response to endogenous stimulus#GO:0071495;response to growth factor#GO:0070848;BMP signaling pathway#GO:0030509;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;cellular response to BMP stimulus#GO:0071773;response to stimulus#GO:0050896;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;enzyme-linked receptor protein signaling pathway#GO:0007167;response to endogenous stimulus#GO:0009719;regulation of cellular process#GO:0050794;cellular response to growth factor stimulus#GO:0071363;cell surface receptor signaling pathway#GO:0007166;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007;response to BMP#GO:0071772;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 CIOIN|Ensembl=ENSCING00000006809.3|UniProtKB=F6UMN4 F6UMN4 LOC100181763 PTHR15901:SF16 TESTICULAR HAPLOID EXPRESSED GENE PROTEIN TESTICULAR HAPLOID EXPRESSED GENE PROTEIN CIOIN|Ensembl=ENSCING00000006427.3|UniProtKB=F6QRK3 F6QRK3 PTHR10985:SF138 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, HES-RELATED HAIRY_ENHANCER-OF-SPLIT RELATED WITH YRPW MOTIF PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;basic helix-loop-helix transcription factor#PC00055 Notch signaling pathway#P00045>E(spl)-C genes#G01541 CIOIN|Ensembl=ENSCING00000022134.1|UniProtKB=H2XY81 H2XY81 LOC100180305 PTHR10553:SF5 SMALL NUCLEAR RIBONUCLEOPROTEIN U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM7 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 RNA splicing factor#PC00148;RNA processing factor#PC00147 CIOIN|Ensembl=ENSCING00000006138.3|UniProtKB=F6R9B7 F6R9B7 PTHR16146:SF48 INTELECTIN FIBRILLAR COLLAGEN NC1 DOMAIN-CONTAINING PROTEIN carbohydrate binding#GO:0030246;binding#GO:0005488;oligosaccharide binding#GO:0070492 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 CIOIN|Ensembl=ENSCING00000014281.2|UniProtKB=F6WP26 F6WP26 PTHR16290:SF0 TRANSCRIPTION FACTOR SMIF DECAPPING ENZYME DCP1 DECAPPING PROTEIN 1, ISOFORM A RNA binding#GO:0003723;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 negative regulation of gene expression#GO:0010629;regulation of catabolic process#GO:0009894;heterocycle catabolic process#GO:0046700;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;nucleobase-containing compound metabolic process#GO:0006139;RNA destabilization#GO:0050779;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;regulation of RNA stability#GO:0043487;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;positive regulation of mRNA catabolic process#GO:0061014;regulation of cellular process#GO:0050794;post-transcriptional regulation of gene expression#GO:0010608;positive regulation of catabolic process#GO:0009896;mRNA destabilization#GO:0061157;nucleobase-containing compound catabolic process#GO:0034655;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;regulation of mRNA stability#GO:0043488;RNA metabolic process#GO:0016070;positive regulation of cellular catabolic process#GO:0031331;cellular nitrogen compound catabolic process#GO:0044270;RNA decapping#GO:0110154;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;mRNA catabolic process#GO:0006402;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;regulation of gene expression#GO:0010468;organic substance catabolic process#GO:1901575;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;positive regulation of mRNA metabolic process#GO:1903313;heterocycle metabolic process#GO:0046483;negative regulation of biosynthetic process#GO:0009890;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;positive regulation of RNA metabolic process#GO:0051254 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;P-body#GO:0000932;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic ribonucleoprotein granule#GO:0036464 RNA processing factor#PC00147;mRNA capping factor#PC00145 TGF-beta signaling pathway#P00052>Co-activators corepressors#P01282 CIOIN|Ensembl=ENSCING00000003791.3|UniProtKB=F7AVN5 F7AVN5 PTHR23504:SF1 MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 10 GH21943P-RELATED secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000001754.3|UniProtKB=F7AM61 F7AM61 LOC100184901 PTHR12692:SF0 DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE-RELATED GH11935P glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein N-linked glycosylation#GO:0006487;protein metabolic process#GO:0019538;protein N-linked glycosylation via asparagine#GO:0018279;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 membrane protein complex#GO:0098796;endoplasmic reticulum protein-containing complex#GO:0140534;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endoplasmic reticulum subcompartment#GO:0098827;oligosaccharyltransferase complex#GO:0008250;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 glycosyltransferase#PC00111 CIOIN|Ensembl=ENSCING00000021858.1|UniProtKB=H2XVI6 H2XVI6 PTHR48228:SF5 SUCCINYL-COA--D-CITRAMALATE COA-TRANSFERASE ALPHA-METHYLACYL-COA RACEMASE transferase#PC00220;metabolite interconversion enzyme#PC00262 Coenzyme A linked carnitine metabolism#P02732>L-carnitine dehydratase#P02864;Carnitine metabolism#P02733>Carnitine dehydratase#P02866 CIOIN|Ensembl=ENSCING00000012164.2|UniProtKB=F6UHP1 F6UHP1 PTHR15706:SF2 SH3 MULTIPLE DOMAIN SH3 AND PX DOMAIN-CONTAINING PROTEIN 2A scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000002696.3|UniProtKB=F6XNX3 F6XNX3 PTHR12103:SF38 5'-NUCLEOTIDASE DOMAIN-CONTAINING 5'-NUCLEOTIDASE DOMAIN-CONTAINING PROTEIN 1 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;5'-nucleotidase activity#GO:0008253;catalytic activity#GO:0003824;nucleotidase activity#GO:0008252;phosphoric ester hydrolase activity#GO:0042578 nucleotide phosphatase#PC00173;phosphatase#PC00181;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000021438.1|UniProtKB=H2Y2Q4 H2Y2Q4 PTHR11211:SF40 IROQUOIS-CLASS HOMEODOMAIN PROTEIN IRX MIRROR, ISOFORM C sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;neurogenesis#GO:0022008;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;multicellular organism development#GO:0007275;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell development#GO:0048468;system development#GO:0048731;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;neuron differentiation#GO:0030182;multicellular organismal process#GO:0032501;regulation of macromolecule biosynthetic process#GO:0010556;generation of neurons#GO:0048699;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 CIOIN|Ensembl=ENSCING00000003615.3|UniProtKB=Q1RL92 Q1RL92 Ci-ZF(C2H2)-130 PTHR12487:SF7 TEASHIRT-RELATED PROTEIN TEASHIRT-RELATED nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 zinc finger transcription factor#PC00244 CIOIN|Ensembl=ENSCING00000012032.2|UniProtKB=F7AND3 F7AND3 LOC100178690 PTHR13088:SF3 FAS APOPTOTIC INHIBITORY MOLECULE FAIM FAS APOPTOTIC INHIBITORY MOLECULE 1 regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;regulation of apoptotic process#GO:0042981;negative regulation of apoptotic signaling pathway#GO:2001234;negative regulation of response to stimulus#GO:0048585;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;regulation of extrinsic apoptotic signaling pathway#GO:2001236;regulation of apoptotic signaling pathway#GO:2001233;negative regulation of apoptotic process#GO:0043066;regulation of response to stimulus#GO:0048583;negative regulation of extrinsic apoptotic signaling pathway#GO:2001237;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;negative regulation of programmed cell death#GO:0043069;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648;regulation of programmed cell death#GO:0043067 CIOIN|Ensembl=ENSCING00000009202.3|UniProtKB=F6WNN3 F6WNN3 PTHR19278:SF9 OROTATE PHOSPHORIBOSYLTRANSFERASE URIDINE 5'-MONOPHOSPHATE SYNTHASE transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;pentosyltransferase activity#GO:0016763;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;pyrimidine nucleotide metabolic process#GO:0006220;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;pyrimidine-containing compound metabolic process#GO:0072527;biosynthetic process#GO:0009058;nucleobase metabolic process#GO:0009112;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;pyrimidine nucleobase metabolic process#GO:0006206;nucleoside monophosphate metabolic process#GO:0009123;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;ribonucleoside monophosphate metabolic process#GO:0009161;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 transferase#PC00220;metabolite interconversion enzyme#PC00262 De novo pyrimidine ribonucleotides biosythesis#P02740>Orotate phosphoribosyltransferase#P02922 CIOIN|Ensembl=ENSCING00000022015.1|UniProtKB=H2XZV4 H2XZV4 LOC100185742 PTHR19850:SF36 GUANINE NUCLEOTIDE-BINDING PROTEIN BETA G PROTEIN BETA GUANINE NUCLEOTIDE-BINDING PROTEIN SUBUNIT BETA-5 molecular adaptor activity#GO:0060090;signaling adaptor activity#GO:0035591;signaling receptor complex adaptor activity#GO:0030159;protein-macromolecule adaptor activity#GO:0030674 response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;response to organic cyclic compound#GO:0014070;signal transduction#GO:0007165;cellular response to endogenous stimulus#GO:0071495;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;cellular response to organic substance#GO:0071310;response to organonitrogen compound#GO:0010243;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to nitrogen compound#GO:1901699;response to nitrogen compound#GO:1901698;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;response to chemical#GO:0042221;dopamine receptor signaling pathway#GO:0007212;cellular response to organonitrogen compound#GO:0071417;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cellular response to organic cyclic compound#GO:0071407;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052 cytoplasm#GO:0005737;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;cytoplasmic side of plasma membrane#GO:0009898;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622;extrinsic component of membrane#GO:0019898 heterotrimeric G-protein#PC00117;G-protein#PC00020 5HT1 type receptor mediated signaling pathway#P04373>G-protein#P04408;5HT4 type receptor mediated signaling pathway#P04376>G-protein#P04430;Histamine H2 receptor mediated signaling pathway#P04386>G-Protein#P04490;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>G-Protein#P01073;Thyrotropin-releasing hormone receptor signaling pathway#P04394>G-Protein#P04584;Beta1 adrenergic receptor signaling pathway#P04377>G-Protein#P04436;Oxytocin receptor mediated signaling pathway#P04391>G-Protein#P04534;Histamine H1 receptor mediated signaling pathway#P04385>G-Protein#P04488;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>G-Protein#P01085;Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Gbeta5L#P00748;5HT2 type receptor mediated signaling pathway#P04374>G-protein#P04416;Opioid prodynorphin pathway#P05916>G-protein#P06002;Metabotropic glutamate receptor group III pathway#P00039>G-Protein#P01045;Cortocotropin releasing factor receptor signaling pathway#P04380>G-Protein#P04458;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>Gbeta#P05930;Metabotropic glutamate receptor group II pathway#P00040>G-protein#P01047;Enkephalin release#P05913>G-Protein (i)#P05974;PI3 kinase pathway#P00048>Gbetagamma#P01188;Enkephalin release#P05913>G-Protein (s)#P05977;Opioid proenkephalin pathway#P05915>G-protein#P05994;Beta3 adrenergic receptor signaling pathway#P04379>G-Protein#P04448;Gonadotropin-releasing hormone receptor pathway#P06664>Gbeta#P06769;Opioid proopiomelanocortin pathway#P05917>G-protein#P06012;Beta2 adrenergic receptor signaling pathway#P04378>G-Protein#P04443 CIOIN|Ensembl=ENSCING00000022563.1|UniProtKB=H2Y2Z4 H2Y2Z4 PTHR12480:SF41 ARGININE DEMETHYLASE AND LYSYL-HYDROXYLASE JMJD JMJC DOMAIN-CONTAINING PROTEIN sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;dioxygenase activity#GO:0051213;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity#GO:0016491 positive regulation of gene expression#GO:0010628;positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of protein metabolic process#GO:0051246;regulation of amide metabolic process#GO:0034248;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;protein modification process#GO:0036211;regulation of cellular component organization#GO:0051128;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;protein hydroxylation#GO:0018126;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;positive regulation of biological process#GO:0048518;positive regulation of translation#GO:0045727;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;regulation of protein-containing complex disassembly#GO:0043244;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;positive regulation of protein metabolic process#GO:0051247;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;post-transcriptional regulation of gene expression#GO:0010608;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;regulation of translation#GO:0006417;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000022372.1|UniProtKB=C6SUS0 C6SUS0 gpb5 PTHR11515:SF13 GLYCOPROTEIN HORMONE BETA CHAIN GLYCOPROTEIN HORMONE BETA 5, ISOFORM A regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576;intracellular anatomical structure#GO:0005622 peptide hormone#PC00179 CIOIN|Ensembl=ENSCING00000000040.3|UniProtKB=F6VV46 F6VV46 LOC100176713 PTHR11675:SF138 N-ACETYLGALACTOSAMINYLTRANSFERASE GLYCOSYLTRANSFERASE 2-LIKE DOMAIN-CONTAINING PROTEIN transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;UDP-glycosyltransferase activity#GO:0008194 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;protein O-linked glycosylation#GO:0006493;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000003658.3|UniProtKB=F7AWQ7 F7AWQ7 LOC100183137 PTHR43028:SF5 3'(2'),5'-BISPHOSPHATE NUCLEOTIDASE 1 3'(2'),5'-BISPHOSPHATE NUCLEOTIDASE 1 hydrolase#PC00121;phosphatase#PC00181 CIOIN|Ensembl=ENSCING00000021769.1|UniProtKB=F7ARY3 F7ARY3 PTHR43539:SF23 FLAVIN-BINDING MONOOXYGENASE-LIKE PROTEIN (AFU_ORTHOLOGUE AFUA_4G09220) FAD-DEPENDENT OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN 2 nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;flavin adenine dinucleotide binding#GO:0050660;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;anion binding#GO:0043168;oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497 response to organic substance#GO:0010033;macromolecule catabolic process#GO:0009057;cellular response to stimulus#GO:0051716;response to endoplasmic reticulum stress#GO:0034976;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;response to organonitrogen compound#GO:0010243;ERAD pathway#GO:0036503;cellular process#GO:0009987;primary metabolic process#GO:0044238;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;cellular response to stress#GO:0033554;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;endoplasmic reticulum lumen#GO:0005788;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 oxygenase#PC00177;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000019021.1|UniProtKB=H2Y356 H2Y356 PTHR10209:SF881 OXIDOREDUCTASE, 2OG-FE II OXYGENASE FAMILY PROTEIN FI07970P-RELATED oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000020416.1|UniProtKB=H2XN70 H2XN70 PTHR13281:SF0 TRANSMEMBRANE PROTEIN 70, MITOCHONDRIAL TRANSMEMBRANE PROTEIN 70, MITOCHONDRIAL cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;protein-containing complex assembly#GO:0065003;mitochondrial proton-transporting ATP synthase complex assembly#GO:0033615;cellular component organization#GO:0016043;mitochondrion organization#GO:0007005;cellular process#GO:0009987 envelope#GO:0031975;cytoplasm#GO:0005737;mitochondrial membrane#GO:0031966;intracellular membrane-bounded organelle#GO:0043231;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000004007.3|UniProtKB=F6VY51 F6VY51 LOC100178877 PTHR31350:SF27 SI:DKEY-261L7.2 HEMIMETHYLATED DNA-BINDING DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000021996.1|UniProtKB=H2XLQ6 H2XLQ6 PTHR12480:SF6 ARGININE DEMETHYLASE AND LYSYL-HYDROXYLASE JMJD 2-OXOGLUTARATE AND IRON-DEPENDENT OXYGENASE JMJD4 sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;dioxygenase activity#GO:0051213;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity#GO:0016491 positive regulation of gene expression#GO:0010628;positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of protein metabolic process#GO:0051246;regulation of amide metabolic process#GO:0034248;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;protein modification process#GO:0036211;regulation of cellular component organization#GO:0051128;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;protein hydroxylation#GO:0018126;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;positive regulation of biological process#GO:0048518;positive regulation of translation#GO:0045727;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;regulation of protein-containing complex disassembly#GO:0043244;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;positive regulation of protein metabolic process#GO:0051247;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;post-transcriptional regulation of gene expression#GO:0010608;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;regulation of translation#GO:0006417;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000007133.3|UniProtKB=F6S9F0 F6S9F0 LOC100176171 PTHR12480:SF32 ARGININE DEMETHYLASE AND LYSYL-HYDROXYLASE JMJD BIFUNCTIONAL ARGININE DEMETHYLASE AND LYSYL-HYDROXYLASE JMJD6 histone modifying activity#GO:0140993;demethylase activity#GO:0032451;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;histone demethylase activity#GO:0032452;binding#GO:0005488;catalytic activity#GO:0003824;dioxygenase activity#GO:0051213;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;protein-containing complex binding#GO:0044877;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000013252.2|UniProtKB=F6SFW9 F6SFW9 PTHR11829:SF363 FORKHEAD BOX PROTEIN FORKHEAD BOX PROTEIN FKH-2 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;anatomical structure morphogenesis#GO:0009653;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 CIOIN|Ensembl=ENSCING00000003515.3|UniProtKB=F7BH75 F7BH75 LOC100185785 PTHR23320:SF171 MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MS4A -RELATED AGAP000247-PA transporter#PC00227 CIOIN|Ensembl=ENSCING00000016252.2|UniProtKB=F6VPL1 F6VPL1 LOC100184820 PTHR34921:SF1 MEIOTIC RECOMBINATION PROTEIN REC114 MEIOTIC RECOMBINATION PROTEIN REC114 CIOIN|Ensembl=ENSCING00000006660.3|UniProtKB=F6TDZ5 F6TDZ5 LOC100179351 PTHR19384:SF10 NITRIC OXIDE SYNTHASE-RELATED NADPH-DEPENDENT DIFLAVIN OXIDOREDUCTASE 1 carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;flavin adenine dinucleotide binding#GO:0050660;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167;oxidoreductase activity#GO:0016491 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000001564.3|UniProtKB=F6VZQ9 F6VZQ9 LOC100176240 PTHR13107:SF0 N6-ADENOSINE-METHYLTRANSFERASE NON-CATALYTIC SUBUNIT N6-ADENOSINE-METHYLTRANSFERASE NON-CATALYTIC SUBUNIT nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA modification#GO:0009451;cellular metabolic process#GO:0044237;mRNA modification#GO:0016556;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;macromolecule methylation#GO:0043414;methylation#GO:0032259;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA methylation#GO:0001510;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;methyltransferase complex#GO:0034708;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA processing factor#PC00147;RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000000113.3|UniProtKB=F6T569 F6T569 PTHR43836:SF2 CATECHOL O-METHYLTRANSFERASE 1-RELATED CATECHOL O-METHYLTRANSFERASE 1-RELATED methyltransferase activity#GO:0008168;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;O-methyltransferase activity#GO:0008171;catalytic activity#GO:0003824 methyltransferase#PC00155;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000022959.1|UniProtKB=H2XVS6 H2XVS6 PTHR12428:SF66 OXA1 MITOCHONDRIAL INNER MEMBRANE PROTEIN OXA1L localization within membrane#GO:0051668;cellular localization#GO:0051641;macromolecule localization#GO:0033036;membrane organization#GO:0061024;protein localization to membrane#GO:0072657;establishment of protein localization to organelle#GO:0072594;cellular component organization#GO:0016043;protein localization to mitochondrion#GO:0070585;cellular process#GO:0009987;establishment of protein localization#GO:0045184;inner mitochondrial membrane organization#GO:0007007;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of protein localization to membrane#GO:0090150;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;establishment of protein localization to mitochondrion#GO:0072655;organelle organization#GO:0006996;establishment of localization in cell#GO:0051649;protein localization to organelle#GO:0033365;mitochondrion organization#GO:0007005;mitochondrial membrane organization#GO:0007006;protein insertion into membrane#GO:0051205 envelope#GO:0031975;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;organelle membrane#GO:0031090;organelle inner membrane#GO:0019866;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227 transporter#PC00227 CIOIN|Ensembl=ENSCING00000000875.3|UniProtKB=F6QQF5 F6QQF5 fgfr PTHR24416:SF550 TYROSINE-PROTEIN KINASE RECEPTOR FIBROBLAST GROWTH FACTOR RECEPTOR HOMOLOG 1-RELATED signaling receptor activity#GO:0038023;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;molecular transducer activity#GO:0060089;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672;transmembrane signaling receptor activity#GO:0004888 signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;positive regulation of cellular metabolic process#GO:0031325;developmental process#GO:0032502;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;regulation of molecular function#GO:0065009;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;positive regulation of phosphorylation#GO:0042327;cellular response to stimulus#GO:0051716;positive regulation of catalytic activity#GO:0043085;multicellular organism development#GO:0007275;positive regulation of phosphorus metabolic process#GO:0010562;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphate metabolic process#GO:0045937;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;multicellular organismal process#GO:0032501;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 receptor complex#GO:0043235;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 CIOIN|Ensembl=ENSCING00000011426.2|UniProtKB=F7ADU2 F7ADU2 zf(nfx1) PTHR12360:SF1 NUCLEAR TRANSCRIPTION FACTOR, X-BOX BINDING 1 NFX1 NF-X1-TYPE ZINC FINGER PROTEIN NFXL1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 zinc finger transcription factor#PC00244 CIOIN|Ensembl=ENSCING00000004197.3|UniProtKB=F6XWN6 F6XWN6 LOC100187159 PTHR45859:SF1 TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT BETA TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT BETA nucleoside-triphosphatase regulator activity#GO:0060589;nucleic acid binding#GO:0003676;translation regulator activity#GO:0045182;GTPase regulator activity#GO:0030695;binding#GO:0005488;organic cyclic compound binding#GO:0097159;molecular function regulator activity#GO:0098772;translation initiation factor activity#GO:0003743;translation regulator activity, nucleic acid binding#GO:0090079;enzyme regulator activity#GO:0030234;translation factor activity, RNA binding#GO:0008135;guanyl-nucleotide exchange factor activity#GO:0005085 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;translational initiation#GO:0006413;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622 translation initiation factor#PC00224;translation factor#PC00223;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000023254.1|UniProtKB=H2XTB6 H2XTB6 PTHR13317:SF4 TRANSMEMBRANE ANTERIOR POSTERIOR TRANSFORMATION PROTEIN 1 HOMOLOG TRANSMEMBRANE ANTERIOR POSTERIOR TRANSFORMATION PROTEIN 1 HOMOLOG cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000002748.3|UniProtKB=F7AHM4 F7AHM4 PTHR12153:SF15 SELENOPROTEIN O PROTEIN ADENYLYLTRANSFERASE SELO, MITOCHONDRIAL CIOIN|Ensembl=ENSCING00000019330.1|UniProtKB=H2XP26 H2XP26 LOC101243380 PTHR10093:SF8 IRON-SULFUR CLUSTER ASSEMBLY ENZYME NIFU HOMOLOG IRON-SULFUR CLUSTER ASSEMBLY ENZYME cation binding#GO:0043169;ferrous iron binding#GO:0008198;small molecule binding#GO:0036094;binding#GO:0005488;iron-sulfur cluster binding#GO:0051536;iron ion binding#GO:0005506;transition metal ion binding#GO:0046914;metal ion binding#GO:0046872;ion binding#GO:0043167 inorganic ion homeostasis#GO:0098771;intracellular iron ion homeostasis#GO:0006879;intracellular monoatomic cation homeostasis#GO:0030003;homeostatic process#GO:0042592;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic ion homeostasis#GO:0006873;chemical homeostasis#GO:0048878;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;monoatomic ion homeostasis#GO:0050801 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 chaperone#PC00072 CIOIN|Ensembl=ENSCING00000008081.3|UniProtKB=F6Z6L6 F6Z6L6 LOC100177936 PTHR18866:SF33 CARBOXYLASE:PYRUVATE/ACETYL-COA/PROPIONYL-COA CARBOXYLASE METHYLCROTONOYL-COA CARBOXYLASE SUBUNIT ALPHA, MITOCHONDRIAL-RELATED ligase#PC00142 Methylmalonyl pathway#P02755>Propionyl-CoA carboxylase#P03033 CIOIN|Ensembl=ENSCING00000021621.1|UniProtKB=H2Y0T2 H2Y0T2 PTHR45618:SF12 MITOCHONDRIAL DICARBOXYLATE CARRIER-RELATED MITOCHONDRIAL UNCOUPLING PROTEIN 1 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 localization#GO:0051179;mitochondrial transport#GO:0006839;establishment of localization#GO:0051234;cellular process#GO:0009987;transmembrane transport#GO:0055085;mitochondrial transmembrane transport#GO:1990542;transport#GO:0006810 secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000015940.2|UniProtKB=F6XSQ9 F6XSQ9 PTHR46075:SF2 CHIMERIN FAMILY MEMBER RHO GTPASE ACTIVATING PROTEIN AT 5A, ISOFORM A CIOIN|Ensembl=ENSCING00000005798.3|UniProtKB=F6RLX1 F6RLX1 LOC100183843 PTHR23430:SF7 HISTONE H2A HISTONE H2A.V nucleosome binding#GO:0031491;nucleic acid binding#GO:0003676;chromatin DNA binding#GO:0031490;binding#GO:0005488;organic cyclic compound binding#GO:0097159;chromatin binding#GO:0003682;DNA binding#GO:0003677;protein-containing complex binding#GO:0044877 negative regulation of gene expression#GO:0010629;negative regulation of cellular metabolic process#GO:0031324;protein-DNA complex organization#GO:0071824;negative regulation of biological process#GO:0048519;negative regulation of biosynthetic process#GO:0009890;heterochromatin formation#GO:0031507;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;negative regulation of gene expression, epigenetic#GO:0045814;cellular process#GO:0009987;epigenetic regulation of gene expression#GO:0040029;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;negative regulation of macromolecule biosynthetic process#GO:0010558;heterochromatin organization#GO:0070828;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;protein-containing complex organization#GO:0043933;regulation of cellular process#GO:0050794;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;chromatin remodeling#GO:0006338;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 CIOIN|Ensembl=ENSCING00000023594.1|UniProtKB=H2XUX4 H2XUX4 PTHR11829:SF402 FORKHEAD BOX PROTEIN FORK HEAD DOMAIN-CONTAINING PROTEIN FD3-RELATED sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;anatomical structure morphogenesis#GO:0009653;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 CIOIN|Ensembl=ENSCING00000018220.1|UniProtKB=H2Y1L1 H2Y1L1 PTHR44942:SF4 METHYLTRANSF_11 DOMAIN-CONTAINING PROTEIN METHYLTRANSFERASE TYPE 11 DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000014197.2|UniProtKB=F6ZPP4 F6ZPP4 LOC100178780 PTHR12441:SF10 ATP SYNTHASE COUPLING FACTOR 6, MITOCHONDRIAL ATP SYNTHASE-COUPLING FACTOR 6, MITOCHONDRIAL envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;ATPase complex#GO:1904949;organelle inner membrane#GO:0019866;mitochondrial proton-transporting ATP synthase complex#GO:0005753;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;proton-transporting two-sector ATPase complex#GO:0016469;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial envelope#GO:0005740;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227;proton-transporting ATP synthase complex#GO:0045259;mitochondrial protein-containing complex#GO:0098798 ATP synthase#PC00002;primary active transporter#PC00068;transporter#PC00227 CIOIN|Ensembl=ENSCING00000007187.3|UniProtKB=F6ZA91 F6ZA91 PTHR21320:SF3 CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX11-RELATED CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX11, MITOCHONDRIAL-RELATED chaperone#PC00072 CIOIN|Ensembl=ENSCING00000014817.2|UniProtKB=F6SA18 F6SA18 PTHR23327:SF42 RING FINGER PROTEIN 127 LON PEPTIDASE N-TERMINAL DOMAIN AND RING FINGER PROTEIN C14F5.10C transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000007104.3|UniProtKB=F6VLR0 F6VLR0 LOC100182783 PTHR31935:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 13 COILED-COIL DOMAIN-CONTAINING PROTEIN 13 CIOIN|Ensembl=ENSCING00000003095.3|UniProtKB=F6PKF9 F6PKF9 PTHR23280:SF25 4.1 G PROTEIN MOESIN_EZRIN_RADIXIN HOMOLOG 1 cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;actomyosin structure organization#GO:0031032;cellular component organization#GO:0016043;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165 CIOIN|Ensembl=ENSCING00000019677.1|UniProtKB=H2XQN8 H2XQN8 LOC100182270 PTHR11452:SF83 ALPHA-GALACTOSIDASE/ALPHA-N-ACETYLGALACTOSAMINIDASE ALPHA-GALACTOSIDASE hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 carbohydrate derivative metabolic process#GO:1901135;glycosyl compound catabolic process#GO:1901658;carbohydrate derivative catabolic process#GO:1901136;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;glycosyl compound metabolic process#GO:1901657;carbohydrate metabolic process#GO:0005975;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 galactosidase#PC00104;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000004462.3|UniProtKB=H2Y1K9 H2Y1K9 PTHR23170:SF3 NY-REN-58 ANTIGEN LEUCINE-RICH REPEAT-CONTAINING PROTEIN 45 CIOIN|Ensembl=ENSCING00000007817.3|UniProtKB=F6WTL7 F6WTL7 PTHR24023:SF1112 COLLAGEN ALPHA COL_CUTICLE_N DOMAIN-CONTAINING PROTEIN-RELATED structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;external encapsulating structure organization#GO:0045229;extracellular matrix organization#GO:0030198 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;extracellular region#GO:0005576 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 Integrin signalling pathway#P00034>Collagen#P00922 CIOIN|Ensembl=ENSCING00000005864.3|UniProtKB=F6ZVC5 F6ZVC5 PTHR24416:SF539 TYROSINE-PROTEIN KINASE RECEPTOR RECEPTOR PROTEIN-TYROSINE KINASE signaling receptor activity#GO:0038023;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;molecular transducer activity#GO:0060089;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672;transmembrane signaling receptor activity#GO:0004888 signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;positive regulation of cellular metabolic process#GO:0031325;developmental process#GO:0032502;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;regulation of molecular function#GO:0065009;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;positive regulation of phosphorylation#GO:0042327;cellular response to stimulus#GO:0051716;positive regulation of catalytic activity#GO:0043085;multicellular organism development#GO:0007275;positive regulation of phosphorus metabolic process#GO:0010562;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphate metabolic process#GO:0045937;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;multicellular organismal process#GO:0032501;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 receptor complex#GO:0043235;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 CIOIN|Ensembl=ENSCING00000019083.1|UniProtKB=H2XS95 H2XS95 PTHR16038:SF4 NOP SEVEN ASSOCIATED PROTEIN 1 WD REPEAT-CONTAINING PROTEIN 74 cellular component organization or biogenesis#GO:0071840;cellular component biogenesis#GO:0044085;ribosome biogenesis#GO:0042254;cellular process#GO:0009987;ribosomal large subunit biogenesis#GO:0042273;ribonucleoprotein complex biogenesis#GO:0022613 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;preribosome, large subunit precursor#GO:0030687;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;nuclear lumen#GO:0031981 RNA processing factor#PC00147;RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000005558.3|UniProtKB=F6UTA8 F6UTA8 PTHR45999:SF4 UNC-13-4A, ISOFORM B UNC-13-4A, ISOFORM B CIOIN|Ensembl=ENSCING00000024888.1|UniProtKB=H2XSV0 H2XSV0 PTHR15601:SF0 STRESS ASSOCIATED ENDOPLASMIC RETICULUM PROTEIN SERP1/RAMP4 GEO09675P1 response to organic substance#GO:0010033;signal transduction#GO:0007165;endoplasmic reticulum unfolded protein response#GO:0030968;cellular response to stimulus#GO:0051716;response to endoplasmic reticulum stress#GO:0034976;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to topologically incorrect protein#GO:0035967;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;response to topologically incorrect protein#GO:0035966;response to unfolded protein#GO:0006986;cellular response to unfolded protein#GO:0034620;biological regulation#GO:0065007;cellular response to stress#GO:0033554;signaling#GO:0023052 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chaperone#PC00072 CIOIN|Ensembl=ENSCING00000023627.1|UniProtKB=H2XY86 H2XY86 PTHR11040:SF140 ZINC/IRON TRANSPORTER ZRT (ZRT), IRT- (IRT-) LIKE PROTEIN TRANSPORTER inorganic molecular entity transmembrane transporter activity#GO:0015318;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;inorganic cation transmembrane transporter activity#GO:0022890;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075 localization#GO:0051179;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;monoatomic cation transport#GO:0006812;transition metal ion transport#GO:0000041;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655 cellular anatomical entity#GO:0110165;membrane#GO:0016020 secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000004946.3|UniProtKB=F7A765 F7A765 PTHR12121:SF34 CARBON CATABOLITE REPRESSOR PROTEIN 4 PROTEIN ANGEL catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters#GO:0016796;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity#GO:0016787;3'-5'-RNA exonuclease activity#GO:0000175;exonuclease activity#GO:0004527;3'-5' exonuclease activity#GO:0008408;RNA nuclease activity#GO:0004540 mRNA polyadenylation factor#PC00146 CIOIN|Ensembl=ENSCING00000000673.3|UniProtKB=F6QSC7 F6QSC7 LOC100180238 PTHR10589:SF17 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE cysteine-type peptidase activity#GO:0008234;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;cysteine-type deubiquitinase activity#GO:0004843 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;protein modification by small protein removal#GO:0070646;protein deubiquitination#GO:0016579;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 cysteine protease#PC00081;protease#PC00190 CIOIN|Ensembl=ENSCING00000001817.3|UniProtKB=F6WJD2 F6WJD2 PTHR10361:SF55 SODIUM-BILE ACID COTRANSPORTER SODIUM-DEPENDENT ORGANIC ANION TRANSPORTER secondary active monocarboxylate transmembrane transporter activity#GO:0015355;inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;organic acid:sodium symporter activity#GO:0005343;organic acid transmembrane transporter activity#GO:0005342;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;bile acid transmembrane transporter activity#GO:0015125;organic anion transmembrane transporter activity#GO:0008514;monoatomic cation transmembrane transporter activity#GO:0008324;active transmembrane transporter activity#GO:0022804;lipid transporter activity#GO:0005319;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;metal ion transmembrane transporter activity#GO:0046873;active monoatomic ion transmembrane transporter activity#GO:0022853;monocarboxylic acid transmembrane transporter activity#GO:0008028;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294 localization#GO:0051179;organic hydroxy compound transport#GO:0015850;organic substance transport#GO:0071702;monocarboxylic acid transport#GO:0015718;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;organic anion transport#GO:0015711;organic acid transport#GO:0015849;transport#GO:0006810;carboxylic acid transport#GO:0046942;lipid localization#GO:0010876;bile acid and bile salt transport#GO:0015721;lipid transport#GO:0006869 primary active transporter#PC00068;transporter#PC00227 CIOIN|Ensembl=ENSCING00000013799.2|UniProtKB=F6R9Y6 F6R9Y6 LOC100185132 PTHR20883:SF51 PHYTANOYL-COA DIOXYGENASE DOMAIN CONTAINING 1 PHYTANOYL-COA HYDROXYLASE oxygenase#PC00177;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000005003.3|UniProtKB=F6TXT5 F6TXT5 LOC100176033 PTHR11760:SF32 30S/40S RIBOSOMAL PROTEIN S3 SMALL RIBOSOMAL SUBUNIT PROTEIN US3 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic small ribosomal subunit#GO:0022627;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;small ribosomal subunit#GO:0015935;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000022634.1|UniProtKB=H2XML4 H2XML4 LOC100186348 PTHR42943:SF2 GLUTATHIONE S-TRANSFERASE KAPPA GLUTATHIONE S-TRANSFERASE KAPPA 1 transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000022506.1|UniProtKB=F6X1F4 F6X1F4 LOC100175794 PTHR24412:SF172 KELCH PROTEIN KELCH-LIKE PROTEIN 10 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000024405.1|UniProtKB=H2XK10 H2XK10 LOC100177999 PTHR23503:SF8 SOLUTE CARRIER FAMILY 2 FACILITATED GLUCOSE TRANSPORTER PROTEIN 1 transmembrane transporter activity#GO:0022857;sugar transmembrane transporter activity#GO:0051119;transporter activity#GO:0005215;carbohydrate transmembrane transporter activity#GO:0015144 localization#GO:0051179;organic substance transport#GO:0071702;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810;cellular process#GO:0009987;carbohydrate transmembrane transport#GO:0034219;carbohydrate transport#GO:0008643 cellular anatomical entity#GO:0110165;membrane#GO:0016020 secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000014901.2|UniProtKB=F6YRB7 F6YRB7 LOC100178450 PTHR14365:SF1 APOPTOSIS REGULATORY PROTEIN SIVA APOPTOSIS REGULATORY PROTEIN SIVA protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102;tumor necrosis factor receptor superfamily binding#GO:0032813;cytokine receptor binding#GO:0005126 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;apoptotic signaling pathway#GO:0097190;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;extrinsic apoptotic signaling pathway#GO:0097191;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;apoptotic process#GO:0006915;biological regulation#GO:0065007;cell death#GO:0008219;programmed cell death#GO:0012501;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 CIOIN|Ensembl=ENSCING00000025156.1|UniProtKB=H2XP99 H2XP99 LOC100175427 PTHR45964:SF9 WSCD FAMILY MEMBER CG9164 SULFOTRANSFERASE CIOIN|Ensembl=ENSCING00000011739.2|UniProtKB=F6TAY9 F6TAY9 LOC100185052 PTHR11839:SF15 UDP/ADP-SUGAR PYROPHOSPHATASE URIDINE DIPHOSPHATE GLUCOSE PYROPHOSPHATASE NUDT14 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;carbohydrate derivative metabolic process#GO:1901135;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;organophosphate metabolic process#GO:0019637;nucleobase-containing small molecule metabolic process#GO:0055086;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152 pyrophosphatase#PC00196 CIOIN|Ensembl=ENSCING00000012634.2|UniProtKB=F6WS92 F6WS92 LOC108950015 PTHR46041:SF2 MITOCHONDRIAL INNER MEMBRANE PROTEASE SUBUNIT 2 MITOCHONDRIAL INNER MEMBRANE PROTEASE SUBUNIT 2 hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular localization#GO:0051641;mitochondrial protein processing#GO:0034982;macromolecule localization#GO:0033036;gene expression#GO:0010467;biosynthetic process#GO:0009058;establishment of protein localization#GO:0045184;protein processing#GO:0016485;establishment of localization#GO:0051234;protein targeting to mitochondrion#GO:0006626;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;protein localization to organelle#GO:0033365;protein metabolic process#GO:0019538;protein processing involved in protein targeting to mitochondrion#GO:0006627;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein targeting#GO:0006605;cellular metabolic process#GO:0044237;establishment of protein localization to organelle#GO:0072594;protein maturation#GO:0051604;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;protein localization to mitochondrion#GO:0070585;protein localization#GO:0008104;primary metabolic process#GO:0044238;localization#GO:0051179;cellular macromolecule localization#GO:0070727;establishment of protein localization to mitochondrion#GO:0072655 envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial envelope#GO:0005740;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227;mitochondrial protein-containing complex#GO:0098798 protease#PC00190;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000001396.3|UniProtKB=F6ZBD0 F6ZBD0 LOC104265605 PTHR12693:SF3 MENIN MENIN sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;chromatin binding#GO:0003682;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;protein-containing complex binding#GO:0044877 negative regulation of biological process#GO:0048519;regulation of cell population proliferation#GO:0042127;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of cell cycle#GO:0045786;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;negative regulation of cell population proliferation#GO:0008285;regulation of cell cycle#GO:0051726;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;histone methyltransferase complex#GO:0035097;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;methyltransferase complex#GO:0034708;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 CCKR signaling map#P06959>MEN1#P07084 CIOIN|Ensembl=ENSCING00000019019.1|UniProtKB=F7A8X9 F7A8X9 PTHR43684:SF1 FAMILY NOT NAMED ENOYL-COA DELTA ISOMERASE 2 CIOIN|Ensembl=ENSCING00000015598.2|UniProtKB=F6ZKL4 F6ZKL4 PTHR24256:SF470 TRYPTASE-RELATED INACTIVE CLIP DOMAIN-CONTAINING SERINE PROTEASE A30 serine protease#PC00203;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000018443.1|UniProtKB=H2XQ32 H2XQ32 PTHR24221:SF656 ATP-BINDING CASSETTE SUB-FAMILY B ABC-TYPE ANTIGEN PEPTIDE TRANSPORTER transmembrane transporter activity#GO:0022857;primary active transmembrane transporter activity#GO:0015399;ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 localization#GO:0051179;establishment of localization#GO:0051234;cellular process#GO:0009987;transmembrane transport#GO:0055085;transport#GO:0006810 cellular anatomical entity#GO:0110165;membrane#GO:0016020 ATP-binding cassette (ABC) transporter#PC00003;transporter#PC00227 CIOIN|Ensembl=ENSCING00000002033.3|UniProtKB=H2Y307 H2Y307 LOC100180570 PTHR12241:SF147 TUBULIN POLYGLUTAMYLASE TUBULIN POLYGLUTAMYLASE TTLL7 cytoskeletal protein binding#GO:0008092;ligase activity#GO:0016874;protein binding#GO:0005515;tubulin binding#GO:0015631;catalytic activity, acting on a protein#GO:0140096;binding#GO:0005488;catalytic activity#GO:0003824 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;microtubule cytoskeleton organization#GO:0000226;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;cellular component organization#GO:0016043;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;nitrogen compound metabolic process#GO:0006807;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;microtubule cytoskeleton#GO:0015630;ciliary basal body#GO:0036064;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;cilium#GO:0005929;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;microtubule or microtubule-binding cytoskeletal protein#PC00157 CIOIN|Ensembl=ENSCING00000002467.3|UniProtKB=F7B4R2 F7B4R2 PTHR15681:SF1 MAD2L1-BINDING PROTEIN MAD2L1-BINDING PROTEIN membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000019389.1|UniProtKB=H2XK74 H2XK74 PTHR13382:SF83 MITOCHONDRIAL ATP SYNTHASE COUPLING FACTOR B F-BOX DOMAIN-CONTAINING PROTEIN cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ATP synthase#PC00002;primary active transporter#PC00068;transporter#PC00227 CIOIN|Ensembl=ENSCING00000012125.2|UniProtKB=F6V7Z4 F6V7Z4 PTHR11709:SF518 MULTI-COPPER OXIDASE MULTICOPPER OXIDASE oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 oxidase#PC00175;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000007175.3|UniProtKB=F6ZAX4 F6ZAX4 PTHR24201:SF2 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 42 kinase modulator#PC00140;kinase inhibitor#PC00139 CIOIN|Ensembl=ENSCING00000010137.3|UniProtKB=A0A1W2WNJ8 A0A1W2WNJ8 LOC100182378 PTHR21244:SF1 MITOCHONDRIAL 28S RIBOSOMAL PROTEIN S24 SMALL RIBOSOMAL SUBUNIT PROTEIN US3M macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;translation#GO:0006412;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 ribosomal protein#PC00202;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000009526.3|UniProtKB=F6XCQ7 F6XCQ7 LOC100175425 PTHR47979:SF33 DRAB11-RELATED DRAB11 GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;anion binding#GO:0043168;ion binding#GO:0043167 localization#GO:0051179;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization#GO:0051234;transport#GO:0006810 cytoplasm#GO:0005737;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular vesicle#GO:0097708;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 small GTPase#PC00208 CIOIN|Ensembl=ENSCING00000011568.2|UniProtKB=A0A1W2W8I4 A0A1W2W8I4 LOC100184404 PTHR11593:SF10 60S RIBOSOMAL PROTEIN L17 60S RIBOSOMAL PROTEIN L17 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cytoplasmic translation#GO:0002181;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic large ribosomal subunit#GO:0022625;large ribosomal subunit#GO:0015934;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000013138.2|UniProtKB=F6ZH24 F6ZH24 PTHR15036:SF83 PIKACHURIN-LIKE PROTEIN AGRIN cell adhesion molecule#PC00069 CIOIN|Ensembl=ENSCING00000008624.3|UniProtKB=F6T1J8 F6T1J8 LOC100175298 PTHR19384:SF17 NITRIC OXIDE SYNTHASE-RELATED NADPH--CYTOCHROME P450 REDUCTASE carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;flavin adenine dinucleotide binding#GO:0050660;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167;oxidoreductase activity#GO:0016491 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 oxidoreductase#PC00176 Vitamin D metabolism and pathway#P04396>P450 reductase#P04605 CIOIN|Ensembl=ENSCING00000014180.2|UniProtKB=F7A7R4 F7A7R4 PTHR10983:SF24 1-ACYLGLYCEROL-3-PHOSPHATE ACYLTRANSFERASE-RELATED 1-ACYLGLYCEROL-3-PHOSPHATE O-ACYLTRANSFERASE 3, ISOFORM E-RELATED acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;O-acyltransferase activity#GO:0008374 cellular anatomical entity#GO:0110165;endomembrane system#GO:0012505 acyltransferase#PC00042 CIOIN|Ensembl=ENSCING00000021776.1|UniProtKB=H2Y3D9 H2Y3D9 PTHR16852:SF2 GTP CYCLOHYDROLASE 1 FEEDBACK REGULATORY PROTEIN GTP CYCLOHYDROLASE 1 FEEDBACK REGULATORY PROTEIN enzyme binding#GO:0019899;protein binding#GO:0005515;binding#GO:0005488 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein-binding activity modulator#PC00095 CIOIN|Ensembl=ENSCING00000002603.3|UniProtKB=F7B369 F7B369 LOC100179866 PTHR23285:SF7 RING FINGER AND KH DOMAIN CONTAINING PROTEIN 1 LD09246P1 RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000008960.3|UniProtKB=F6Q5T5 F6Q5T5 PTHR13723:SF200 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE ADAM METALLOPEPTIDASE WITH THROMBOSPONDIN TYPE 1 MOTIF B, ISOFORM B hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular component organization or biogenesis#GO:0071840;extracellular structure organization#GO:0043062;external encapsulating structure organization#GO:0045229;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;cellular component organization#GO:0016043;cellular process#GO:0009987;protein metabolic process#GO:0019538;extracellular matrix organization#GO:0030198;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944 metalloprotease#PC00153;protease#PC00190 CIOIN|Ensembl=ENSCING00000009198.3|UniProtKB=F6WNR2 F6WNR2 LOC100179058 PTHR12730:SF0 HSDA/SDA1-RELATED PROTEIN SDA1 HOMOLOG cellular component biogenesis#GO:0044085;ribosomal subunit export from nucleus#GO:0000054;cellular localization#GO:0051641;organelle localization#GO:0051640;transport#GO:0006810;cellular process#GO:0009987;ribosomal large subunit biogenesis#GO:0042273;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;nuclear export#GO:0051168;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;ribonucleoprotein complex biogenesis#GO:0022613;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;ribosome biogenesis#GO:0042254;nuclear transport#GO:0051169;establishment of organelle localization#GO:0051656;protein-containing complex localization#GO:0031503 intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000007113.3|UniProtKB=F6SWY4 F6SWY4 PTHR45820:SF4 FI23527P1 ZINC TRANSPORTER 63C, ISOFORM F inorganic molecular entity transmembrane transporter activity#GO:0015318;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;inorganic cation transmembrane transporter activity#GO:0022890;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075 inorganic ion homeostasis#GO:0098771;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;homeostatic process#GO:0042592;inorganic ion transmembrane transport#GO:0098660;chemical homeostasis#GO:0048878;cellular process#GO:0009987;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;monoatomic ion homeostasis#GO:0050801;localization#GO:0051179;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation transport#GO:0006812;transition metal ion transport#GO:0000041;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655 cellular anatomical entity#GO:0110165;membrane#GO:0016020 CIOIN|Ensembl=ENSCING00000003712.3|UniProtKB=F6WUP4 F6WUP4 PTHR24418:SF367 TYROSINE-PROTEIN KINASE INACTIVE TYROSINE-PROTEIN KINASE KIN-32 protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;non-membrane spanning protein tyrosine kinase activity#GO:0004715;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cell junction#GO:0030054;cell-substrate junction#GO:0030055;cellular anatomical entity#GO:0110165;anchoring junction#GO:0070161;focal adhesion#GO:0005925 non-receptor tyrosine protein kinase#PC00168 Angiogenesis#P00005>FAK#P00209;VEGF signaling pathway#P00056>FAK#P01420;Integrin signalling pathway#P00034>FAK#P00932 CIOIN|Ensembl=ENSCING00000000035.3|UniProtKB=F6VV86 F6VV86 LOC101242901 PTHR13291:SF0 JOSEPHIN 1, 2 JOSEPHIN-LIKE PROTEIN cysteine-type peptidase activity#GO:0008234;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;cysteine-type deubiquitinase activity#GO:0004843 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;protein modification by small protein removal#GO:0070646;protein deubiquitination#GO:0016579;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cysteine protease#PC00081;protease#PC00190 CIOIN|Ensembl=ENSCING00000000502.3|UniProtKB=F6VQ02 F6VQ02 LOC100176230 PTHR19877:SF13 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT I SERINE-THREONINE KINASE RECEPTOR-ASSOCIATED PROTEIN nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;RNA processing#GO:0006396;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;protein-RNA complex assembly#GO:0022618;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;spliceosomal snRNP assembly#GO:0000387;organic substance metabolic process#GO:0071704;mRNA splicing, via spliceosome#GO:0000398;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;protein-containing complex organization#GO:0043933;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;ribonucleoprotein complex biogenesis#GO:0022613;mRNA processing#GO:0006397;protein-RNA complex organization#GO:0071826;RNA splicing, via transesterification reactions#GO:0000375 SMN-Sm protein complex#GO:0034719;cytoplasm#GO:0005737;SMN complex#GO:0032797;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;Sm-like protein family complex#GO:0120114;intracellular anatomical structure#GO:0005622 translation initiation factor#PC00224;translation factor#PC00223 CIOIN|Ensembl=ENSCING00000018114.1|UniProtKB=H2Y1X0 H2Y1X0 PTHR43620:SF7 GLYCEROPHOSPHORYL DIESTER PHOSPHODIESTERASE GLYCEROPHOSPHODIESTER PHOSPHODIESTERASE GDPD5-RELATED hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphoric diester hydrolase activity#GO:0008081;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 phosphodiesterase#PC00185;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000010738.3|UniProtKB=F6S4U2 F6S4U2 PTHR11089:SF30 GTP-BINDING PROTEIN-RELATED GUANINE NUCLEOTIDE-BINDING PROTEIN-LIKE 3 HOMOLOG CIOIN|Ensembl=ENSCING00000002620.3|UniProtKB=F7B2W7 F7B2W7 PTHR46102:SF2 AXIN AXIN binding#GO:0005488;ubiquitin-like protein ligase binding#GO:0044389;protein binding#GO:0005515;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;ubiquitin protein ligase binding#GO:0031625;beta-catenin binding#GO:0008013;kinase binding#GO:0019900 regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of catabolic process#GO:0009894;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of proteolysis involved in protein catabolic process#GO:1903050;positive regulation of protein modification process#GO:0031401;positive regulation of proteolysis#GO:0045862;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;positive regulation of biological process#GO:0048518;negative regulation of cell communication#GO:0010648;regulation of kinase activity#GO:0043549;cellular developmental process#GO:0048869;positive regulation of proteolysis involved in protein catabolic process#GO:1903052;negative regulation of signaling#GO:0023057;positive regulation of phosphorus metabolic process#GO:0010562;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;positive regulation of catabolic process#GO:0009896;negative regulation of signal transduction#GO:0009968;negative regulation of Wnt signaling pathway#GO:0030178;positive regulation of protein catabolic process#GO:0045732;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;negative regulation of biological process#GO:0048519;regulation of phosphate metabolic process#GO:0019220;regulation of signaling#GO:0023051;developmental process#GO:0032502;positive regulation of molecular function#GO:0044093;positive regulation of proteasomal protein catabolic process#GO:1901800;regulation of protein catabolic process#GO:0042176;regulation of catalytic activity#GO:0050790;cell differentiation#GO:0030154;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;negative regulation of cellular process#GO:0048523;positive regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032436;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;regulation of cell communication#GO:0010646;regulation of protein kinase activity#GO:0045859;regulation of proteolysis#GO:0030162;positive regulation of protein phosphorylation#GO:0001934;positive regulation of phosphorylation#GO:0042327;negative regulation of response to stimulus#GO:0048585;positive regulation of catalytic activity#GO:0043085;cellular process#GO:0009987;regulation of canonical Wnt signaling pathway#GO:0060828;regulation of proteasomal protein catabolic process#GO:0061136;regulation of primary metabolic process#GO:0080090;cell development#GO:0048468;positive regulation of protein metabolic process#GO:0051247;regulation of macromolecule metabolic process#GO:0060255;positive regulation of protein kinase activity#GO:0045860;regulation of Wnt signaling pathway#GO:0030111;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;negative regulation of canonical Wnt signaling pathway#GO:0090090;regulation of transferase activity#GO:0051338;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 Wnt signaling pathway#P00057>Wnt Target Genes#G01558;Angiogenesis#P00005>Axin#P00253;Wnt signaling pathway#P00057>Axin#P01429 CIOIN|Ensembl=ENSCING00000025050.1|UniProtKB=H2XUR5 H2XUR5 PTHR22906:SF52 PROPERDIN ADHESION G PROTEIN-COUPLED RECEPTOR B1 CIOIN|Ensembl=ENSCING00000009496.3|UniProtKB=F6Y921 F6Y921 PTHR15172:SF1 GALACTOCEREBROSIDASE GALACTOCEREBROSIDASE hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;carbohydrate derivative catabolic process#GO:1901136;glycolipid metabolic process#GO:0006664;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;lipid catabolic process#GO:0016042;cellular process#GO:0009987;liposaccharide metabolic process#GO:1903509;sphingolipid metabolic process#GO:0006665;primary metabolic process#GO:0044238;ceramide metabolic process#GO:0006672;membrane lipid metabolic process#GO:0006643;nitrogen compound metabolic process#GO:0006807;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;sphingolipid catabolic process#GO:0030149;cellular lipid metabolic process#GO:0044255;cellular lipid catabolic process#GO:0044242;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248 cytoplasm#GO:0005737;lysosome#GO:0005764;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;lytic vacuole#GO:0000323;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 galactosidase#PC00104 CIOIN|Ensembl=ENSCING00000024533.1|UniProtKB=H2Y2N4 H2Y2N4 PTHR28632:SF2 TRANSLATION MACHINERY-ASSOCIATED PROTEIN 7 TRANSLATION MACHINERY-ASSOCIATED PROTEIN 7 CIOIN|Ensembl=ENSCING00000016651.2|UniProtKB=F6X7P9 F6X7P9 PTHR47272:SF1 DDE_TNP_1_7 DOMAIN-CONTAINING PROTEIN PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 3-LIKE CIOIN|Ensembl=ENSCING00000021541.1|UniProtKB=H2XXE3 H2XXE3 PTHR23282:SF142 APICAL ENDOSOMAL GLYCOPROTEIN PRECURSOR. MAM DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000018973.1|UniProtKB=H2XN57 H2XN57 PTHR22588:SF3 VWFA DOMAIN-CONTAINING PROTEIN VWFA DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000002955.3|UniProtKB=F6R472 F6R472 PTHR11932:SF168 CULLIN CULLIN-3 enzyme binding#GO:0019899;protein binding#GO:0005515;ubiquitin protein ligase binding#GO:0031625;binding#GO:0005488;ubiquitin-like protein ligase binding#GO:0044389 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;cullin-RING ubiquitin ligase complex#GO:0031461;transferase complex#GO:1990234 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000018202.1|UniProtKB=H2XUN7 H2XUN7 LOC100183202 PTHR19325:SF560 COMPLEMENT COMPONENT-RELATED SUSHI DOMAIN-CONTAINING SUSHI, VON WILLEBRAND FACTOR TYPE A, EGF AND PENTRAXIN DOMAIN-CONTAINING PROTEIN 1 complement component#PC00078 CIOIN|Ensembl=ENSCING00000014494.2|UniProtKB=F6XLS2 F6XLS2 PTHR13283:SF11 KREV INTERACTION TRAPPED 1-RELATED KREV INTERACTION TRAPPED PROTEIN 1 regulation of biological process#GO:0050789;negative regulation of multicellular organismal process#GO:0051241;negative regulation of biological process#GO:0048519;regulation of multicellular organismal process#GO:0051239;regulation of developmental process#GO:0050793;regulation of anatomical structure morphogenesis#GO:0022603;regulation of vasculature development#GO:1901342;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;homeostatic process#GO:0042592;regulation of angiogenesis#GO:0045765;negative regulation of angiogenesis#GO:0016525;regulation of multicellular organismal development#GO:2000026;cellular homeostasis#GO:0019725 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000006960.3|UniProtKB=F6SZE1 F6SZE1 LOC100177711 PTHR23509:SF10 PA-PL1 PHOSPHOLIPASE FAMILY LD21067P hydrolase activity#GO:0016787;lipase activity#GO:0016298;hydrolase activity, acting on ester bonds#GO:0016788;phospholipase activity#GO:0004620;catalytic activity#GO:0003824 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 phospholipase#PC00186;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000003241.3|UniProtKB=F6Z5P6 F6Z5P6 hdcl PTHR11999:SF167 GROUP II PYRIDOXAL-5-PHOSPHATE DECARBOXYLASE AROMATIC-L-AMINO-ACID DECARBOXYLASE lyase activity#GO:0016829;carboxy-lyase activity#GO:0016831;carbon-carbon lyase activity#GO:0016830;catalytic activity#GO:0003824 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 decarboxylase#PC00089 Nicotine pharmacodynamics pathway#P06587>DDC#P06608;5-Hydroxytryptamine biosynthesis#P04371>Aromatic L-amino acid decarboxylase#P04400;Dopamine receptor mediated signaling pathway#P05912>DOPA decarb.#P05961;Adrenaline and noradrenaline biosynthesis#P00001>DOPA decarb.#P00066 CIOIN|Ensembl=ENSCING00000015297.2|UniProtKB=F7B8E9 F7B8E9 PTHR22802:SF396 C-TYPE LECTIN SUPERFAMILY MEMBER C-TYPE LECTIN DOMAIN-CONTAINING PROTEIN membrane traffic protein#PC00150 CIOIN|Ensembl=ENSCING00000002377.3|UniProtKB=F6R554 F6R554 LOC100175975 PTHR11675:SF68 N-ACETYLGALACTOSAMINYLTRANSFERASE N-ACETYLGALACTOSAMINYLTRANSFERASE 7 transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;UDP-glycosyltransferase activity#GO:0008194 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;protein O-linked glycosylation#GO:0006493;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000019037.1|UniProtKB=H2XVQ0 H2XVQ0 PTHR13826:SF14 INTESTINAL TREFOIL FACTOR-RELATED TREFOIL FACTOR 2 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 CIOIN|Ensembl=ENSCING00000021108.1|UniProtKB=H2XLC7 H2XLC7 PTHR24016:SF0 CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 4 CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 4 membrane traffic protein#PC00150 CIOIN|Ensembl=ENSCING00000006444.3|UniProtKB=F6QKP0 F6QKP0 PTHR22972:SF8 SERINE/THREONINE PROTEIN KINASE PROTEIN KINASE DOMAIN-CONTAINING PROTEIN transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;phosphorylation#GO:0016310;protein phosphorylation#GO:0006468;cellular process#GO:0009987;protein metabolic process#GO:0019538;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000023556.1|UniProtKB=H2XN59 H2XN59 PTHR11929:SF145 ALPHA- 1,3 -FUCOSYLTRANSFERASE ALPHA-(1,3)-FUCOSYLTRANSFERASE FUT-1 transferase activity#GO:0016740;fucosyltransferase activity#GO:0008417;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 glycosylation#GO:0070085;metabolic process#GO:0008152 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000023385.1|UniProtKB=H2XS72 H2XS72 PTHR22808:SF3 NCL1 YEAST -RELATED NOL1/NOP2/FMU SUN DOMAIN-CONTAINING 5-METHYLCYTOSINE RRNA METHYLTRANSFERASE NSUN4 methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;RNA modification#GO:0009451;rRNA modification#GO:0000154;RNA processing#GO:0006396;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;ribosome biogenesis#GO:0042254;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;rRNA methylation#GO:0031167;nucleic acid metabolic process#GO:0090304;methylation#GO:0032259;macromolecule methylation#GO:0043414;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;RNA methylation#GO:0001510 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;mitochondrial large ribosomal subunit#GO:0005762;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;mitochondrial ribosome#GO:0005761;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;ribosomal subunit#GO:0044391;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;organellar ribosome#GO:0000313;protein-containing complex#GO:0032991;large ribosomal subunit#GO:0015934;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;ribosome#GO:0005840;mitochondrial protein-containing complex#GO:0098798 RNA methyltransferase#PC00033 CIOIN|Ensembl=ENSCING00000020584.1|UniProtKB=H2XR28 H2XR28 PTHR23147:SF270 SERINE/ARGININE RICH SPLICING FACTOR RNA-BINDING PROTEIN RNP-1 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;nuclear speck#GO:0016607;organelle#GO:0043226;nuclear body#GO:0016604;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA splicing factor#PC00148;RNA processing factor#PC00147;RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000003812.3|UniProtKB=F6ZT62 F6ZT62 LOC100187539 PTHR46010:SF1 PROTEIN IWS1 HOMOLOG PROTEIN IWS1 HOMOLOG poly(A)+ mRNA export from nucleus#GO:0016973;mRNA export from nucleus#GO:0006406;cellular localization#GO:0051641;macromolecule biosynthetic process#GO:0009059;macromolecule localization#GO:0033036;establishment of RNA localization#GO:0051236;macromolecule metabolic process#GO:0043170;transport#GO:0006810;nucleic acid transport#GO:0050657;nitrogen compound transport#GO:0071705;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;mRNA transport#GO:0051028;RNA localization#GO:0006403;localization#GO:0051179;organic substance transport#GO:0071702;nuclear export#GO:0051168;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;RNA transport#GO:0050658;nucleobase-containing compound transport#GO:0015931;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;nuclear transport#GO:0051169;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000004204.3|UniProtKB=A0A1W3JF95 A0A1W3JF95 LOC100184616 PTHR14413:SF16 RIBOSOMAL PROTEIN L17 LARGE RIBOSOMAL SUBUNIT PROTEIN BL17M structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;large ribosomal subunit#GO:0015934;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000015619.2|UniProtKB=F6ZK09 F6ZK09 LOC100183802 PTHR16064:SF3 BTB POZ DOMAIN CONTAINING 7 BTB_POZ DOMAIN-CONTAINING PROTEIN 7 CIOIN|Ensembl=ENSCING00000001478.3|UniProtKB=F6TI28 F6TI28 PTHR24055:SF79 MITOGEN-ACTIVATED PROTEIN KINASE MITOGEN-ACTIVATED PROTEIN KINASE 15 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;signaling#GO:0023052 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Integrin signalling pathway#P00034>ERK#P00907;EGF receptor signaling pathway#P00018>ERK1-2#P00543;Ras Pathway#P04393>ERK#P04542;Interleukin signaling pathway#P00036>ERK#P00965;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>MAPK#P00835;PDGF signaling pathway#P00047>ERK#P01143;FGF signaling pathway#P00021>ERK1-2#P00627;Interferon-gamma signaling pathway#P00035>Serine kinase#P00955;Alzheimer disease-amyloid secretase pathway#P00003>MAPK#P00099;Toll receptor signaling pathway#P00054>ERK1#P01358;Apoptosis signaling pathway#P00006>MAPK#P00269;TGF-beta signaling pathway#P00052>p42/p44MAPKs#P01293;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>ERK#P00889;Parkinson disease#P00049>ERK#P01211;Endothelin signaling pathway#P00019>ERK#P00566 CIOIN|Ensembl=ENSCING00000002811.4|UniProtKB=F6WZS8 F6WZS8 PTHR10012:SF0 SERINE/THREONINE-PROTEIN PHOSPHATASE 2A REGULATORY SUBUNIT B SERINE_THREONINE-PROTEIN PHOSPHATASE 2A ACTIVATOR phosphatase regulator activity#GO:0019208;molecular function activator activity#GO:0140677;catalytic activity#GO:0003824;molecular function regulator activity#GO:0098772;protein phosphatase regulator activity#GO:0019888;peptidyl-prolyl cis-trans isomerase activity#GO:0003755;enzyme activator activity#GO:0008047;isomerase activity#GO:0016853;catalytic activity, acting on a protein#GO:0140096;enzyme regulator activity#GO:0030234 cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;mitotic spindle organization#GO:0007052;microtubule-based process#GO:0007017;organelle organization#GO:0006996;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;cell cycle#GO:0007049;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;spindle organization#GO:0007051;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cellular process#GO:0009987;mitotic cell cycle process#GO:1903047 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;protein serine/threonine phosphatase complex#GO:0008287;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 phosphatase activator#PC00182;phosphatase modulator#PC00184 CIOIN|Ensembl=ENSCING00000001856.3|UniProtKB=F6T6Y0 F6T6Y0 prx1 PTHR46271:SF4 HOMEOBOX PROTEIN, PUTATIVE-RELATED HOMEOBOX PROTEIN, PUTATIVE-RELATED sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 homeodomain transcription factor#PC00119 CIOIN|Ensembl=ENSCING00000021067.1|UniProtKB=H2XT70 H2XT70 PTHR11441:SF0 THYMIDINE KINASE THYMIDINE KINASE, CYTOSOLIC transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;nucleoside metabolic process#GO:0009116;carbohydrate derivative metabolic process#GO:1901135;pyrimidine-containing compound metabolic process#GO:0072527;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;glycosyl compound metabolic process#GO:1901657;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086 nucleotide kinase#PC00172;metabolite interconversion enzyme#PC00262 Salvage pyrimidine deoxyribonucleotides#P02774>Thymidine kinase#P03147;Salvage pyrimidine deoxyribonucleotides#P02774>Deoxyuridine kinase#P03146 CIOIN|Ensembl=ENSCING00000019733.1|UniProtKB=H2XYZ0 H2XYZ0 PTHR24208:SF105 LIM/HOMEOBOX PROTEIN LHX DLIM1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;neurogenesis#GO:0022008;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;multicellular organism development#GO:0007275;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;system development#GO:0048731;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;neuron differentiation#GO:0030182;multicellular organismal process#GO:0032501;regulation of macromolecule biosynthetic process#GO:0010556;generation of neurons#GO:0048699;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 CIOIN|Ensembl=ENSCING00000001681.3|UniProtKB=F6X873 F6X873 PTHR24046:SF7 SIGNAL PEPTIDE, CUB AND EGF-LIKE DOMAIN-CONTAINING CUB DOMAIN-CONTAINING PROTEIN regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cell surface#GO:0009986;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 extracellular matrix glycoprotein#PC00100;extracellular matrix protein#PC00102 CIOIN|Ensembl=ENSCING00000012491.2|UniProtKB=F6ZK74 F6ZK74 PTHR10336:SF80 PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C FAMILY PROTEIN C2 DOMAIN-CONTAINING PROTEIN hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;phospholipase C activity#GO:0004629;phospholipase activity#GO:0004620;phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578 lipid metabolic process#GO:0006629;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;regulation of sequestering of calcium ion#GO:0051282;regulation of localization#GO:0032879;inorganic ion transmembrane transport#GO:0098660;phospholipid metabolic process#GO:0006644;phosphorus metabolic process#GO:0006793;calcium ion transport#GO:0006816;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;glycerolipid metabolic process#GO:0046486;establishment of localization#GO:0051234;monoatomic cation transport#GO:0006812;intracellular signal transduction#GO:0035556;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;calcium ion transmembrane transport#GO:0070588;cellular metabolic process#GO:0044237;release of sequestered calcium ion into cytosol#GO:0051209;cell communication#GO:0007154;glycerophospholipid metabolic process#GO:0006650;phosphatidylinositol metabolic process#GO:0046488;cellular process#GO:0009987;primary metabolic process#GO:0044238;localization#GO:0051179;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;monoatomic ion transmembrane transport#GO:0034220;calcium ion transmembrane import into cytosol#GO:0097553;biological regulation#GO:0065007;organophosphate metabolic process#GO:0019637;monoatomic ion transport#GO:0006811;cellular lipid metabolic process#GO:0044255;negative regulation of sequestering of calcium ion#GO:0051283;monoatomic cation transmembrane transport#GO:0098655 phospholipase#PC00186 CIOIN|Ensembl=ENSCING00000018429.1|UniProtKB=H2XLX2 H2XLX2 PTHR21716:SF4 TRANSMEMBRANE PROTEIN TRANSMEMBRANE PROTEIN 245 CIOIN|Ensembl=ENSCING00000022055.1|UniProtKB=H2XP64 H2XP64 PTHR23050:SF518 CALCIUM BINDING PROTEIN AT16150P-RELATED cation binding#GO:0043169;small molecule binding#GO:0036094;molecular function regulator activity#GO:0098772;binding#GO:0005488;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;enzyme regulator activity#GO:0030234 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 calmodulin-related#PC00061 B cell activation#P00010>Calmodulin#P00375;Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Calmodulin#P00755;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Phosphorylase b kinase#P00716;T cell activation#P00053>Calmodulin#P01305 CIOIN|Ensembl=ENSCING00000014505.2|UniProtKB=F6WA40 F6WA40 LOC100182868 PTHR23320:SF158 MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MS4A -RELATED CREB-BINDING PROTEIN-LIKE ISOFORM X1 transporter#PC00227 CIOIN|Ensembl=ENSCING00000006661.3|UniProtKB=F6TE09 F6TE09 PTHR12484:SF4 B-LYMPHOCYTE ANTIGEN-RELATED A-KINASE ANCHOR PROTEIN 17A CIOIN|Ensembl=ENSCING00000011481.2|UniProtKB=F6XI39 F6XI39 LOC113475831 PTHR24251:SF30 OVOCHYMASE-RELATED MEMBRANE FRIZZLED-RELATED PROTEIN serine protease#PC00203;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000013720.2|UniProtKB=F6Z0W4 F6Z0W4 PTHR12910:SF2 NADH-UBIQUINONE OXIDOREDUCTASE SUBUNIT B17.2 NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 12 response to stimulus#GO:0050896;response to stress#GO:0006950;response to oxidative stress#GO:0006979 envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;respiratory chain complex#GO:0098803;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transporter complex#GO:1990351;oxidoreductase complex#GO:1990204;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;respirasome#GO:0070469;mitochondrial respiratory chain complex I#GO:0005747;protein-containing complex#GO:0032991;mitochondrial envelope#GO:0005740;mitochondrial respirasome#GO:0005746;transmembrane transporter complex#GO:1902495;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227;respiratory chain complex I#GO:0045271;NADH dehydrogenase complex#GO:0030964;mitochondrial protein-containing complex#GO:0098798 oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000009942.3|UniProtKB=F6R5R8 F6R5R8 LOC100177389 PTHR10671:SF34 EPITHELIAL MEMBRANE PROTEIN-RELATED PROTEIN NKG7 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cytoskeletal protein#PC00085 CIOIN|Ensembl=ENSCING00000012223.2|UniProtKB=F7BP11 F7BP11 PTHR21646:SF74 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 19 cysteine protease#PC00081;protease#PC00190 CIOIN|Ensembl=ENSCING00000007134.3|UniProtKB=F6S925 F6S925 PTHR12560:SF0 LONGEVITY ASSURANCE FACTOR 1 LAG1 LD18904P transferase activity#GO:0016740;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity#GO:0003824;N-acyltransferase activity#GO:0016410 lipid metabolic process#GO:0006629;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;membrane lipid biosynthetic process#GO:0046467;sphingolipid metabolic process#GO:0006665;ceramide metabolic process#GO:0006672;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;membrane lipid metabolic process#GO:0006643;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;ceramide biosynthetic process#GO:0046513;cellular lipid metabolic process#GO:0044255;amide metabolic process#GO:0043603;sphingolipid biosynthetic process#GO:0030148;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000006131.3|UniProtKB=F6VR17 F6VR17 PTHR11485:SF34 TRANSFERRIN SIGNAL RECOGNITION PARTICLE RECEPTOR SUBUNIT BETA localization#GO:0051179;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;protein localization to endoplasmic reticulum#GO:0070972;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;protein targeting#GO:0006605;protein targeting to ER#GO:0045047;establishment of protein localization to organelle#GO:0072594;protein localization to organelle#GO:0033365;establishment of protein localization to endoplasmic reticulum#GO:0072599;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;endoplasmic reticulum protein-containing complex#GO:0140534;rough endoplasmic reticulum membrane#GO:0030867;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;rough endoplasmic reticulum#GO:0005791;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 transfer/carrier protein#PC00219 CIOIN|Ensembl=ENSCING00000004961.3|UniProtKB=F6X9K2 F6X9K2 LOC100183149 PTHR24073:SF263 DRAB5-RELATED RAB-LIKE PROTEIN 2A-RELATED GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824 localization#GO:0051179;organic substance transport#GO:0071702;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;transport#GO:0006810;protein transport#GO:0015031;nitrogen compound transport#GO:0071705;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104 cellular anatomical entity#GO:0110165;endomembrane system#GO:0012505 small GTPase#PC00208;G-protein#PC00020 CIOIN|Ensembl=ENSCING00000019043.1|UniProtKB=H2XWK2 H2XWK2 PTHR36916:SF3 TRANSMEMBRANE PROTEIN SI:DKEY-229D11.5 CIOIN|Ensembl=ENSCING00000006931.3|UniProtKB=F6VPC0 F6VPC0 PTHR10075:SF100 BASIGIN RELATED FASCICLIN-2 cell adhesion molecule binding#GO:0050839;cell-cell adhesion mediator activity#GO:0098632;protein binding#GO:0005515;binding#GO:0005488 neuron projection guidance#GO:0097485;cell recognition#GO:0008037;neurogenesis#GO:0022008;cell projection organization#GO:0030030;developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cellular anatomical entity morphogenesis#GO:0032989;system development#GO:0048731;cell differentiation#GO:0030154;axon guidance#GO:0007411;anatomical structure morphogenesis#GO:0009653;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;axonogenesis#GO:0007409;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;homophilic cell adhesion via plasma membrane adhesion molecules#GO:0007156;cell-cell adhesion via plasma-membrane adhesion molecules#GO:0098742;cell-cell adhesion#GO:0098609;cellular component organization#GO:0016043;cell adhesion#GO:0007155;cell morphogenesis#GO:0000902;cellular process#GO:0009987;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;cell morphogenesis involved in neuron differentiation#GO:0048667;anatomical structure development#GO:0048856;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699 neuron projection#GO:0043005;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886;axon#GO:0030424 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000024018.1|UniProtKB=H2XPC8 H2XPC8 PTHR10676:SF365 DYNEIN HEAVY CHAIN FAMILY PROTEIN AAA+ ATPASE DOMAIN-CONTAINING PROTEIN cytoskeletal motor activity#GO:0003774;microtubule motor activity#GO:0003777;protein binding#GO:0005515;ATP-dependent activity#GO:0140657;binding#GO:0005488 cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;outer dynein arm assembly#GO:0036158;cell projection organization#GO:0030030;microtubule-based movement#GO:0007018;microtubule cytoskeleton organization#GO:0000226;cilium or flagellum-dependent cell motility#GO:0001539;protein-containing complex assembly#GO:0065003;cell motility#GO:0048870;cellular component organization#GO:0016043;axoneme assembly#GO:0035082;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031;cilium movement involved in cell motility#GO:0060294;cilium movement#GO:0003341;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cilium-dependent cell motility#GO:0060285;microtubule-based process#GO:0007017;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;microtubule bundle formation#GO:0001578;axonemal dynein complex assembly#GO:0070286;cytoskeleton organization#GO:0007010;plasma membrane bounded cell projection assembly#GO:0120031 axoneme#GO:0005930;outer dynein arm#GO:0036157;catalytic complex#GO:1902494;cytoplasmic region#GO:0099568;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;microtubule associated complex#GO:0005875;axonemal dynein complex#GO:0005858;non-membrane-bounded organelle#GO:0043228;motile cilium#GO:0031514;protein-containing complex#GO:0032991;9+2 motile cilium#GO:0097729;microtubule cytoskeleton#GO:0015630;ciliary plasm#GO:0097014;plasma membrane bounded cell projection cytoplasm#GO:0032838;membrane-bounded organelle#GO:0043227;dynein complex#GO:0030286;cell projection#GO:0042995;cytoskeleton#GO:0005856;cilium#GO:0005929 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 CIOIN|Ensembl=ENSCING00000019613.1|UniProtKB=H2XKW8 H2XKW8 LOC100179180 PTHR45640:SF26 HEAT SHOCK PROTEIN HSP-12.2-RELATED RE23625P chaperone#PC00072 VEGF signaling pathway#P00056>HSP27#P01412;Angiogenesis#P00005>HSP27#P00231 CIOIN|Ensembl=ENSCING00000001272.3|UniProtKB=F6ZVR9 F6ZVR9 PTHR19325:SF560 COMPLEMENT COMPONENT-RELATED SUSHI DOMAIN-CONTAINING SUSHI, VON WILLEBRAND FACTOR TYPE A, EGF AND PENTRAXIN DOMAIN-CONTAINING PROTEIN 1 complement component#PC00078 CIOIN|Ensembl=ENSCING00000011262.2|UniProtKB=F6YTB6 F6YTB6 LOC100185723 PTHR23048:SF45 MYOSIN LIGHT CHAIN 1, 3 CALMODULIN LIKE 4 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;myosin complex#GO:0016459;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 CIOIN|Ensembl=ENSCING00000021192.1|UniProtKB=H2XP08 H2XP08 PTHR45710:SF26 C-TYPE LECTIN DOMAIN-CONTAINING PROTEIN 180 RH26557P defense/immunity protein#PC00090 CIOIN|Ensembl=ENSCING00000003147.3|UniProtKB=F6QIX3 F6QIX3 LOC100183139 PTHR13980:SF15 CDC68 RELATED FACT COMPLEX SUBUNIT SPT16 nucleosome binding#GO:0031491;protein-containing complex binding#GO:0044877;binding#GO:0005488;chromatin binding#GO:0003682 cellular aromatic compound metabolic process#GO:0006725;DNA-templated transcription#GO:0006351;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;DNA-templated transcription elongation#GO:0006354;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;RNA biosynthetic process#GO:0032774;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nucleobase-containing compound biosynthetic process#GO:0034654;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;aromatic compound biosynthetic process#GO:0019438;transcription elongation by RNA polymerase II#GO:0006368;transcription by RNA polymerase II#GO:0006366;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;transcription elongation factor complex#GO:0008023;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 chromatin/chromatin-binding, or -regulatory protein#PC00077 CIOIN|Ensembl=ENSCING00000014586.2|UniProtKB=F6SYR3 F6SYR3 LOC100179118 PTHR18952:SF124 CARBONIC ANHYDRASE CARBONIC ANHYDRASE 7 carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829;hydro-lyase activity#GO:0016836;catalytic activity#GO:0003824 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 dehydratase#PC00091;lyase#PC00144 CIOIN|Ensembl=ENSCING00000006351.3|UniProtKB=F6UFN6 F6UFN6 PTHR24300:SF397 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 2U1 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;tetrapyrrole binding#GO:0046906;steroid hydroxylase activity#GO:0008395;oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497;heme binding#GO:0020037 response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;response to chemical#GO:0042221;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 oxygenase#PC00177;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000016701.2|UniProtKB=F6RTT6 F6RTT6 PTHR47972:SF28 KINESIN-LIKE PROTEIN KLP-3 KINESIN-LIKE PROTEIN KLP-3 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 cellular process#GO:0009987;microtubule-based process#GO:0007017 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 CIOIN|Ensembl=ENSCING00000005305.3|UniProtKB=Q8WSS1 Q8WSS1 CiGi1 PTHR10218:SF227 GTP-BINDING PROTEIN ALPHA SUBUNIT G PROTEIN ALPHA I SUBUNIT GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;ribonucleoside triphosphate phosphatase activity#GO:0017111;G protein-coupled receptor binding#GO:0001664;signaling receptor binding#GO:0005102 regulation of biological process#GO:0050789;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cytoplasm#GO:0005737;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;cytoplasmic side of plasma membrane#GO:0009898;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622;extrinsic component of membrane#GO:0019898 heterotrimeric G-protein#PC00117;G-protein#PC00020 Enkephalin release#P05913>G-Protein (i)#P05974;5HT1 type receptor mediated signaling pathway#P04373>G-protein#P04408;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Gialpha#P00712;Opioid proenkephalin pathway#P05915>G-protein#P05994;Opioid proopiomelanocortin pathway#P05917>G-protein#P06012;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>G-Protein#P01085;Metabotropic glutamate receptor group III pathway#P00039>G-Protein#P01045;Opioid prodynorphin pathway#P05916>G-protein#P06002;PI3 kinase pathway#P00048>Galpha#P01199;Metabotropic glutamate receptor group II pathway#P00040>G-protein#P01047 CIOIN|Ensembl=ENSCING00000009223.3|UniProtKB=F6W1Y5 F6W1Y5 LOC100187421 PTHR13078:SF56 PEROXISOMAL MULTIFUNCTIONAL ENZYME TYPE 2-RELATED PEROXISOMAL MULTIFUNCTIONAL ENZYME TYPE 2 lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;hydro-lyase activity#GO:0016836;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;lipid oxidation#GO:0034440;cellular metabolic process#GO:0044237;lipid catabolic process#GO:0016042;lipid modification#GO:0030258;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;fatty acid catabolic process#GO:0009062;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;fatty acid metabolic process#GO:0006631;small molecule catabolic process#GO:0044282;fatty acid beta-oxidation#GO:0006635;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;cellular lipid metabolic process#GO:0044255;cellular lipid catabolic process#GO:0044242;carboxylic acid metabolic process#GO:0019752;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;monocarboxylic acid catabolic process#GO:0072329 CIOIN|Ensembl=ENSCING00000009058.3|UniProtKB=F6R2A5 F6R2A5 LOC100178764 PTHR10199:SF110 THROMBOSPONDIN TSP C-TERMINAL DOMAIN-CONTAINING PROTEIN external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165 cell adhesion molecule#PC00069 CIOIN|Ensembl=ENSCING00000001864.3|UniProtKB=F6T6X1 F6T6X1 PTHR13681:SF24 SURVIVAL OF MOTOR NEURON-RELATED-SPLICING FACTOR 30-RELATED TUDOR DOMAIN-CONTAINING PROTEIN 3 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA splicing factor#PC00148;RNA processing factor#PC00147 CIOIN|Ensembl=ENSCING00000019211.1|UniProtKB=H2XUN3 H2XUN3 LOC100184078 PTHR28637:SF1 DNA REPLICATION FACTOR CDT1 DNA REPLICATION FACTOR CDT1 enzyme binding#GO:0019899;protein binding#GO:0005515;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;negative regulation of biological process#GO:0048519;protein-DNA complex organization#GO:0071824;signal transduction#GO:0007165;regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA metabolic process#GO:0051052;cell cycle process#GO:0022402;protein-containing complex assembly#GO:0065003;negative regulation of cell cycle process#GO:0010948;protein-DNA complex assembly#GO:0065004;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;cell cycle checkpoint signaling#GO:0000075;mitotic cell cycle#GO:0000278;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;DNA-templated DNA replication#GO:0006261;intracellular signal transduction#GO:0035556;negative regulation of cellular process#GO:0048523;signaling#GO:0023052;cell cycle DNA replication#GO:0044786;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;nuclear DNA replication#GO:0033260;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;negative regulation of cell cycle#GO:0045786;regulation of cell cycle phase transition#GO:1901987;negative regulation of cell cycle phase transition#GO:1901988;cellular metabolic process#GO:0044237;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;regulation of cell cycle process#GO:0010564;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;DNA integrity checkpoint signaling#GO:0031570;nucleic acid metabolic process#GO:0090304;regulation of macromolecule metabolic process#GO:0060255;protein-containing complex organization#GO:0043933;regulation of nucleobase-containing compound metabolic process#GO:0019219;DNA replication checkpoint signaling#GO:0000076;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;DNA replication#GO:0006260;regulation of metabolic process#GO:0019222;DNA metabolic process#GO:0006259;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA metabolism protein#PC00009 CIOIN|Ensembl=ENSCING00000001877.3|UniProtKB=F6SJU9 F6SJU9 LOC100187361 PTHR11220:SF72 HEME-BINDING PROTEIN-RELATED HEME-BINDING PROTEIN 2-LIKE ISOFORM X2 tetrapyrrole binding#GO:0046906;binding#GO:0005488;organic cyclic compound binding#GO:0097159;heme binding#GO:0020037 CIOIN|Ensembl=ENSCING00000012011.2|UniProtKB=F7B763 F7B763 PTHR44942:SF4 METHYLTRANSF_11 DOMAIN-CONTAINING PROTEIN METHYLTRANSFERASE TYPE 11 DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000019492.1|UniProtKB=H2XR17 H2XR17 PTHR12570:SF92 FAMILY NOT NAMED SPICHTHYIN, ISOFORM B localization#GO:0051179;monoatomic cation transport#GO:0006812;metal ion transport#GO:0030001;establishment of localization#GO:0051234;monoatomic ion transport#GO:0006811;transport#GO:0006810 cellular anatomical entity#GO:0110165;membrane#GO:0016020 secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000008283.3|UniProtKB=F6QH68 F6QH68 LOC100179243 PTHR12737:SF9 DIMETHYLARGININE DIMETHYLAMINOHYDROLASE DIMETHYLARGININASE amino acid binding#GO:0016597;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;carboxylic acid binding#GO:0031406;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;anion binding#GO:0043168;ion binding#GO:0043167;organic acid binding#GO:0043177 positive regulation of nitrogen compound metabolic process#GO:0051173;oxoacid metabolic process#GO:0043436;regulation of nitrogen compound metabolic process#GO:0051171;arginine metabolic process#GO:0006525;positive regulation of cellular metabolic process#GO:0031325;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of cellular biosynthetic process#GO:0031326;regulation of cellular process#GO:0050794;regulation of biosynthetic process#GO:0009889;nitrogen compound metabolic process#GO:0006807;biological regulation#GO:0065007;alpha-amino acid metabolic process#GO:1901605;carboxylic acid metabolic process#GO:0019752;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;amino acid metabolic process#GO:0006520;regulation of cellular metabolic process#GO:0031323;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000005977.3|UniProtKB=F6VTF7 F6VTF7 pax2_5_8-b PTHR45636:SF41 PAIRED BOX PROTEIN PAX-6-RELATED-RELATED PAIRED BOX PROTEIN PAX-6-RELATED sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 homeodomain transcription factor#PC00119 CIOIN|Ensembl=ENSCING00000002503.3|UniProtKB=F7AJJ2 F7AJJ2 PTHR19325:SF560 COMPLEMENT COMPONENT-RELATED SUSHI DOMAIN-CONTAINING SUSHI, VON WILLEBRAND FACTOR TYPE A, EGF AND PENTRAXIN DOMAIN-CONTAINING PROTEIN 1 complement component#PC00078 CIOIN|Ensembl=ENSCING00000006848.3|UniProtKB=F7AFK8 F7AFK8 PTHR12210:SF139 DULLARD PROTEIN PHOSPHATASE CARBOXY-TERMINAL DOMAIN RNA POLYMERASE II POLYPEPTIDE A SMALL PHOSPHATASE 1 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;protein serine/threonine phosphatase activity#GO:0004722;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 protein phosphatase#PC00195;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000007323.3|UniProtKB=F6YKJ2 F6YKJ2 LOC100182371 PTHR10807:SF128 MYOTUBULARIN-RELATED PHOSPHATIDYLINOSITOL-3,5-BISPHOSPHATE 3-PHOSPHATASE cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;phosphatase#PC00181 CIOIN|Ensembl=ENSCING00000009330.3|UniProtKB=F6ZM65 F6ZM65 PTHR44019:SF8 WD REPEAT-CONTAINING PROTEIN 55 POC1 CENTRIOLAR PROTEIN HOMOLOG cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 CIOIN|Ensembl=ENSCING00000018564.1|UniProtKB=H2XU26 H2XU26 LOC100179550 PTHR24369:SF211 ANTIGEN BSP, PUTATIVE-RELATED LEUCINE-RICH REPEAT-CONTAINING PROTEIN 15-LIKE cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 CIOIN|Ensembl=ENSCING00000014646.2|UniProtKB=F7BI82 F7BI82 LOC100181326 PTHR24291:SF201 CYTOCHROME P450 FAMILY 4 CYTOCHROME P450, FAMILY 4, SUBFAMILY B, POLYPEPTIDE 7 oxygenase#PC00177;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000000995.3|UniProtKB=F6YLE1 F6YLE1 PTHR15495:SF7 NEGATIVE REGULATOR OF VESICLE FORMATION-RELATED GPI INOSITOL-DEACYLASE hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;lipid metabolic process#GO:0006629;cellular localization#GO:0051641;carbohydrate derivative metabolic process#GO:1901135;transport#GO:0006810;glycolipid metabolic process#GO:0006664;vesicle-mediated transport#GO:0016192;cellular metabolic process#GO:0044237;phosphatidylinositol metabolic process#GO:0046488;glycerophospholipid metabolic process#GO:0006650;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;liposaccharide metabolic process#GO:1903509;Golgi vesicle transport#GO:0048193;GPI anchor metabolic process#GO:0006505;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;localization#GO:0051179;glycerolipid metabolic process#GO:0046486;membrane lipid metabolic process#GO:0006643;establishment of localization#GO:0051234;establishment of localization in cell#GO:0051649;organophosphate metabolic process#GO:0019637;intracellular transport#GO:0046907;cellular lipid metabolic process#GO:0044255;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transporter#PC00227 CIOIN|Ensembl=ENSCING00000021752.1|UniProtKB=H2XLI2 H2XLI2 LOC100180225 PTHR44129:SF13 WD REPEAT-CONTAINING PROTEIN POP1 LISSENCEPHALY-1 HOMOLOG A-RELATED CIOIN|Ensembl=ENSCING00000001740.3|UniProtKB=F7AMQ9 F7AMQ9 PTHR12570:SF65 FAMILY NOT NAMED MAGNESIUM TRANSPORTER NIPA9-RELATED localization#GO:0051179;monoatomic cation transport#GO:0006812;metal ion transport#GO:0030001;establishment of localization#GO:0051234;monoatomic ion transport#GO:0006811;transport#GO:0006810 cellular anatomical entity#GO:0110165;membrane#GO:0016020 secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000022232.1|UniProtKB=H2XSK9 H2XSK9 LOC100180911 PTHR12011:SF471 ADHESION G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 2 PROFILE 2 DOMAIN-CONTAINING PROTEIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 CIOIN|Ensembl=ENSCING00000003915.3|UniProtKB=F6SML2 F6SML2 LOC445772 PTHR10218:SF365 GTP-BINDING PROTEIN ALPHA SUBUNIT EGL-30 GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;ribonucleoside triphosphate phosphatase activity#GO:0017111;G protein-coupled receptor binding#GO:0001664;signaling receptor binding#GO:0005102 response to organic substance#GO:0010033;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;response to organic cyclic compound#GO:0014070;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cellular response to endogenous stimulus#GO:0071495;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;cellular response to organic substance#GO:0071310;response to organonitrogen compound#GO:0010243;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to nitrogen compound#GO:1901699;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;response to nitrogen compound#GO:1901698;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;response to chemical#GO:0042221;dopamine receptor signaling pathway#GO:0007212;cellular response to organonitrogen compound#GO:0071417;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cellular response to organic cyclic compound#GO:0071407;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052 cytoplasm#GO:0005737;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;cytoplasmic side of plasma membrane#GO:0009898;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622;extrinsic component of membrane#GO:0019898 heterotrimeric G-protein#PC00117;G-protein#PC00020 Endothelin signaling pathway#P00019>Gq#P00586;Metabotropic glutamate receptor group I pathway#P00041>G-Protein#P01057;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>G-Protein#P01073;Thyrotropin-releasing hormone receptor signaling pathway#P04394>G-Protein#P04584;Oxytocin receptor mediated signaling pathway#P04391>G-Protein#P04534;Wnt signaling pathway#P00057>Galpha#P01451;Histamine H1 receptor mediated signaling pathway#P04385>G-Protein#P04488;5HT2 type receptor mediated signaling pathway#P04374>G-protein#P04416;PI3 kinase pathway#P00048>Galpha#P01199;Cortocotropin releasing factor receptor signaling pathway#P04380>G-Protein#P04458 CIOIN|Ensembl=ENSCING00000004110.3|UniProtKB=Q4H2Q8 Q4H2Q8 Ci-SWI_SNF PTHR10799:SF879 SNF2/RAD54 HELICASE FAMILY CHROMATIN-REMODELING COMPLEX ATPASE CHAIN ISWI ATP-dependent activity, acting on DNA#GO:0008094;nucleic acid binding#GO:0003676;ATP-dependent activity#GO:0140657;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on DNA#GO:0140097 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-DNA complex#GO:0032993;chromosome#GO:0005694;chromatin#GO:0000785;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA helicase#PC00011;DNA metabolism protein#PC00009 Wnt signaling pathway#P00057>SWI/SNF#P01435 CIOIN|Ensembl=ENSCING00000006304.3|UniProtKB=F7ANK8 F7ANK8 LOC100180969 PTHR14499:SF67 POTASSIUM CHANNEL TETRAMERIZATION DOMAIN-CONTAINING BTB_POZ DOMAIN-CONTAINING PROTEIN TIWAZ scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000018332.1|UniProtKB=H2XWL5 H2XWL5 PTHR10161:SF14 TARTRATE-RESISTANT ACID PHOSPHATASE TYPE 5 TARTRATE-RESISTANT ACID PHOSPHATASE TYPE 5 hydrolase#PC00121;phosphatase#PC00181 CIOIN|Ensembl=ENSCING00000003144.3|UniProtKB=F6R725 F6R725 PTHR10746:SF6 50S RIBOSOMAL PROTEIN L4 LARGE RIBOSOMAL SUBUNIT PROTEIN UL4M structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 ribosomal protein#PC00202;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000014388.2|UniProtKB=F7AFE0 F7AFE0 PTHR45762:SF3 ZINC FINGER RNA-BINDING PROTEIN ZINC-FINGER PROTEIN AT 72D, ISOFORM B RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000019940.1|UniProtKB=H2XP51 H2XP51 PTHR23072:SF0 PHOSPHATIDYLINOSITOL GLYCAN-RELATED GPI ETHANOLAMINE PHOSPHATE TRANSFERASE 2 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;phospholipid biosynthetic process#GO:0008654;macromolecule modification#GO:0043412;organophosphate biosynthetic process#GO:0090407;phosphatidylinositol biosynthetic process#GO:0006661;glycolipid metabolic process#GO:0006664;protein modification process#GO:0036211;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;lipid biosynthetic process#GO:0008610;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;protein lipidation#GO:0006497;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;glycerolipid biosynthetic process#GO:0045017;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;glycerophospholipid metabolic process#GO:0006650;phosphatidylinositol metabolic process#GO:0046488;organic substance biosynthetic process#GO:1901576;liposaccharide metabolic process#GO:1903509;cellular process#GO:0009987;GPI anchor metabolic process#GO:0006505;membrane lipid biosynthetic process#GO:0046467;lipoprotein biosynthetic process#GO:0042158;primary metabolic process#GO:0044238;GPI anchor biosynthetic process#GO:0006506;carbohydrate derivative biosynthetic process#GO:1901137;membrane lipid metabolic process#GO:0006643;glycerophospholipid biosynthetic process#GO:0046474;glycolipid biosynthetic process#GO:0009247;organophosphate metabolic process#GO:0019637;lipoprotein metabolic process#GO:0042157;cellular lipid metabolic process#GO:0044255 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000022961.1|UniProtKB=H2Y1M1 H2Y1M1 LOC100182997 PTHR13183:SF0 AXONEMAL INNER ARM DYNEIN LIGHT CHAIN 28 AXONEMAL DYNEIN LIGHT INTERMEDIATE POLYPEPTIDE 1 protein binding#GO:0005515;binding#GO:0005488 axoneme#GO:0005930;cytoplasmic region#GO:0099568;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;plasma membrane bounded cell projection cytoplasm#GO:0032838;ciliary plasm#GO:0097014;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cytoskeleton#GO:0005856;cilium#GO:0005929 cytoskeletal protein#PC00085;microtubule or microtubule-binding cytoskeletal protein#PC00157 CIOIN|Ensembl=ENSCING00000005320.3|UniProtKB=F7BPM7 F7BPM7 PTHR22588:SF3 VWFA DOMAIN-CONTAINING PROTEIN VWFA DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000003447.3|UniProtKB=Q4H352 Q4H352 Ci-NF45 PTHR46447:SF1 INTERLEUKIN ENHANCER-BINDING FACTOR INTERLEUKIN ENHANCER-BINDING FACTOR 2 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;double-stranded RNA binding#GO:0003725;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of RNA biosynthetic process#GO:2001141;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of RNA metabolic process#GO:0051254;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 ribonucleoprotein complex#GO:1990904;catalytic step 2 spliceosome#GO:0071013;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transcription cofactor#PC00217 CIOIN|Ensembl=ENSCING00000024074.1|UniProtKB=H2XPR0 H2XPR0 LOC100180604 PTHR45775:SF6 RAD, GEM/KIR FAMILY MEMBER 2, ISOFORM C RAD, GEM_KIR FAMILY MEMBER 2, ISOFORM C CIOIN|Ensembl=ENSCING00000004164.3|UniProtKB=F7B623 F7B623 PTHR21771:SF0 MITOCHONDRIA-EATING PROTEIN-RELATED MITOCHONDRIA-EATING PROTEIN macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;autophagy of mitochondrion#GO:0000422;cellular process#GO:0009987;organelle disassembly#GO:1903008;primary metabolic process#GO:0044238;process utilizing autophagic mechanism#GO:0061919;cellular component organization or biogenesis#GO:0071840;cellular component disassembly#GO:0022411;organelle organization#GO:0006996;nitrogen compound metabolic process#GO:0006807;catabolic process#GO:0009056;mitochondrion organization#GO:0007005;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;autophagy#GO:0006914;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248 envelope#GO:0031975;bounding membrane of organelle#GO:0098588;mitochondrial membrane#GO:0031966;intracellular membrane-bounded organelle#GO:0043231;mitochondrial outer membrane#GO:0005741;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867 CIOIN|Ensembl=ENSCING00000003549.3|UniProtKB=F7AYB2 F7AYB2 LOC100177404 PTHR11237:SF4 COENZYME Q10 BIOSYNTHESIS PROTEIN 7 5-DEMETHOXYUBIQUINONE HYDROXYLASE, MITOCHONDRIAL CIOIN|Ensembl=ENSCING00000004977.3|UniProtKB=F7B0W3 F7B0W3 PTHR46240:SF1 SER/THR PROTEIN KINASE ULK4 SERINE_THREONINE-PROTEIN KINASE ULK4 non-receptor serine/threonine protein kinase#PC00167 CIOIN|Ensembl=ENSCING00000019119.1|UniProtKB=H2XPX7 H2XPX7 PTHR23220:SF133 INTEGRIN ALPHA INTEGRIN ALPHA-PS2 cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;integrin binding#GO:0005178;binding#GO:0005488;signaling receptor binding#GO:0005102 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cell adhesion mediated by integrin#GO:0033627;cell-cell adhesion#GO:0098609;cell communication#GO:0007154;cell adhesion#GO:0007155;cell-substrate adhesion#GO:0031589;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cell-matrix adhesion#GO:0007160;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;integrin-mediated signaling pathway#GO:0007229;biological regulation#GO:0065007;signaling#GO:0023052 receptor complex#GO:0043235;membrane protein complex#GO:0098796;external side of plasma membrane#GO:0009897;cell surface#GO:0009986;protein-containing complex#GO:0032991;plasma membrane signaling receptor complex#GO:0098802;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 cell adhesion molecule#PC00069;integrin#PC00126 Integrin signalling pathway#P00034>Integrin alpha#P00941 CIOIN|Ensembl=ENSCING00000023325.1|UniProtKB=H2XKX9 H2XKX9 LOC100179516 PTHR35348:SF1 TESTIS, PROSTATE AND PLACENTA-EXPRESSED PROTEIN TESTIS, PROSTATE AND PLACENTA-EXPRESSED PROTEIN CIOIN|Ensembl=ENSCING00000009762.3|UniProtKB=F6ZTJ9 F6ZTJ9 PTHR23236:SF119 EUKARYOTIC TRANSLATION INITIATION FACTOR 4B/4H NUCLEAR RNA-BINDING PROTEIN SART-3 translation initiation factor#PC00224;translation factor#PC00223 CIOIN|Ensembl=ENSCING00000008725.3|UniProtKB=F6VQX3 F6VQX3 LOC494428 PTHR12100:SF0 SEC10 EXOCYST COMPLEX COMPONENT 5 localization#GO:0051179;localization within membrane#GO:0051668;cellular localization#GO:0051641;vesicle-mediated transport to the plasma membrane#GO:0098876;exocytosis#GO:0006887;establishment of localization#GO:0051234;secretion#GO:0046903;post-Golgi vesicle-mediated transport#GO:0006892;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;Golgi to plasma membrane transport#GO:0006893;export from cell#GO:0140352;secretion by cell#GO:0032940 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;vesicle tethering complex#GO:0099023;exocyst#GO:0000145;cell cortex#GO:0005938;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 membrane trafficking regulatory protein#PC00151 CIOIN|Ensembl=ENSCING00000022880.1|UniProtKB=H2XTW4 H2XTW4 PTHR35836:SF1 VCBS REPEAT-CONTAINING PROTEIN VCBS REPEAT-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000002992.3|UniProtKB=F6QFI4 F6QFI4 LOC100178515 PTHR13085:SF0 MICROSOMAL SIGNAL PEPTIDASE 25 KDA SUBUNIT SIGNAL PEPTIDASE COMPLEX SUBUNIT 2 cellular localization#GO:0051641;macromolecule localization#GO:0033036;peptide metabolic process#GO:0006518;gene expression#GO:0010467;biosynthetic process#GO:0009058;establishment of protein localization#GO:0045184;protein processing#GO:0016485;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;protein localization to organelle#GO:0033365;establishment of protein localization to endoplasmic reticulum#GO:0072599;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;protein localization to endoplasmic reticulum#GO:0070972;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein targeting#GO:0006605;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;establishment of protein localization to organelle#GO:0072594;protein targeting to ER#GO:0045047;protein maturation#GO:0051604;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;protein localization#GO:0008104;primary metabolic process#GO:0044238;localization#GO:0051179;cellular macromolecule localization#GO:0070727;signal peptide processing#GO:0006465 membrane protein complex#GO:0098796;peptidase complex#GO:1905368;endoplasmic reticulum protein-containing complex#GO:0140534;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 protease#PC00190;protein modifying enzyme#PC00260 Vasopressin synthesis#P04395>Signal Peptidase#P04589 CIOIN|Ensembl=ENSCING00000011868.2|UniProtKB=F6Z2A5 F6Z2A5 PTHR10272:SF0 PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE carboxylic ester hydrolase activity#GO:0052689;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000008707.3|UniProtKB=F6WCT6 F6WCT6 PTHR16528:SF2 GOLGI-ASSOCIATED PDZ AND COILED-COIL MOTIF-CONTAINING GOLGI-ASSOCIATED PDZ AND COILED-COIL MOTIF-CONTAINING PROTEIN protein binding#GO:0005515;transmembrane transporter binding#GO:0044325;binding#GO:0005488 regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of localization#GO:0032879;regulation of cellular localization#GO:0060341;negative regulation of cellular process#GO:0048523;regulation of protein localization#GO:0032880 intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;coated vesicle#GO:0030135;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;clathrin-coated vesicle#GO:0030136;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;Golgi-associated vesicle#GO:0005798;membrane-bounded organelle#GO:0043227;transport vesicle#GO:0030133;trans-Golgi network transport vesicle#GO:0030140 membrane traffic protein#PC00150 CIOIN|Ensembl=ENSCING00000020534.1|UniProtKB=H2Y1V9 H2Y1V9 LOC100179400 PTHR12002:SF116 CLAUDIN CLAUDIN-11-LIKE cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cell-cell junction organization#GO:0045216;cellular component biogenesis#GO:0044085;cell-cell junction assembly#GO:0007043;cell junction organization#GO:0034330;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;cell adhesion#GO:0007155;cellular process#GO:0009987 tight junction#GO:0070160;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cell junction#GO:0030054;bicellular tight junction#GO:0005923;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;apical junction complex#GO:0043296;plasma membrane#GO:0005886 cell junction protein#PC00070;tight junction#PC00214 CIOIN|Ensembl=ENSCING00000005603.3|UniProtKB=F7BBV8 F7BBV8 PTHR12894:SF27 CNH DOMAIN CONTAINING TRANSFORMING GROWTH FACTOR-BETA RECEPTOR-ASSOCIATED PROTEIN 1 vesicle fusion#GO:0006906;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;process utilizing autophagic mechanism#GO:0061919;cellular component organization or biogenesis#GO:0071840;membrane fusion#GO:0061025;establishment of localization#GO:0051234;organelle organization#GO:0006996;catabolic process#GO:0009056;vesicle organization#GO:0016050;autophagy#GO:0006914;organelle fusion#GO:0048284;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;membrane#GO:0016020;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000005659.3|UniProtKB=F6Y1Q3 F6Y1Q3 LOC100182144 PTHR11135:SF0 HISTONE ACETYLTRANSFERASE-RELATED ELONGATOR COMPLEX PROTEIN 3 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA modification#GO:0009451;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;tRNA modification#GO:0006400;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;tRNA wobble uridine modification#GO:0002098;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077;histone modifying enzyme#PC00261 CIOIN|Ensembl=ENSCING00000003784.3|UniProtKB=F6TIK7 F6TIK7 PTHR23254:SF15 EIF4G DOMAIN PROTEIN POLYADENYLATE-BINDING PROTEIN-INTERACTING PROTEIN 1 nucleic acid binding#GO:0003676;translation regulator activity#GO:0045182;translation regulator activity, nucleic acid binding#GO:0090079;binding#GO:0005488;organic cyclic compound binding#GO:0097159 regulation of protein metabolic process#GO:0051246;regulation of amide metabolic process#GO:0034248;regulation of nitrogen compound metabolic process#GO:0051171;regulation of translational initiation#GO:0006446;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biosynthetic process#GO:0009889;post-transcriptional regulation of gene expression#GO:0010608;biological regulation#GO:0065007;regulation of translation#GO:0006417;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000002193.3|UniProtKB=F6S4Q0 F6S4Q0 LOC100177845 PTHR18919:SF156 ACETYL-COA C-ACYLTRANSFERASE ACETYL-COA ACETYLTRANSFERASE, MITOCHONDRIAL acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;acetyltransferase activity#GO:0016407;catalytic activity#GO:0003824 oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;lipid oxidation#GO:0034440;cellular metabolic process#GO:0044237;lipid catabolic process#GO:0016042;lipid modification#GO:0030258;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;fatty acid catabolic process#GO:0009062;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;fatty acid metabolic process#GO:0006631;small molecule catabolic process#GO:0044282;fatty acid beta-oxidation#GO:0006635;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;cellular lipid metabolic process#GO:0044255;cellular lipid catabolic process#GO:0044242;carboxylic acid metabolic process#GO:0019752;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;monocarboxylic acid catabolic process#GO:0072329 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 acyltransferase#PC00042 CCKR signaling map#P06959>ACAT1#G07285;CCKR signaling map#P06959>ACAT1#G06992 CIOIN|Ensembl=ENSCING00000007194.3|UniProtKB=F6YRX9 F6YRX9 PTHR43899:SF13 RH59310P RH59310P oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 CIOIN|Ensembl=ENSCING00000019919.1|UniProtKB=H2XZ93 H2XZ93 PTHR14843:SF2 DEUBIQUITINATING PROTEIN VCIP135 DEUBIQUITINATING PROTEIN VCPIP1 cysteine-type peptidase activity#GO:0008234;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;cysteine-type deubiquitinase activity#GO:0004843 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;endoplasmic reticulum organization#GO:0007029;Golgi organization#GO:0007030;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;membrane organization#GO:0061024;macromolecule metabolic process#GO:0043170;protein K48-linked deubiquitination#GO:0071108;organelle membrane fusion#GO:0090174;endomembrane system organization#GO:0010256;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular component organization#GO:0016043;cellular process#GO:0009987;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;membrane fusion#GO:0061025;organelle organization#GO:0006996;nitrogen compound metabolic process#GO:0006807;protein modification by small protein removal#GO:0070646;protein deubiquitination#GO:0016579;protein metabolic process#GO:0019538;organelle fusion#GO:0048284;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cysteine protease#PC00081;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000019681.1|UniProtKB=H2XSC8 H2XSC8 PTHR36978:SF4 P-LOOP CONTAINING NUCLEOTIDE TRIPHOSPHATE HYDROLASE P-LOOP CONTAINING NUCLEOSIDE TRIPHOSPHATE HYDROLASE PROTEIN metabolite interconversion enzyme#PC00262;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000023356.1|UniProtKB=H2XYC6 H2XYC6 PTHR46420:SF1 BETA-1,4-GLUCURONYLTRANSFERASE 1 BETA-1,4-GLUCURONYLTRANSFERASE 1 glucuronosyltransferase activity#GO:0015020;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;UDP-glycosyltransferase activity#GO:0008194 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;protein O-linked glycosylation#GO:0006493;protein O-linked mannosylation#GO:0035269;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;protein mannosylation#GO:0035268;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085;mannosylation#GO:0097502 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000003848.3|UniProtKB=A0A1W2WEA2 A0A1W2WEA2 LOC100181027 PTHR23359:SF234 NUCLEOTIDE KINASE ADENYLATE KINASE 2, MITOCHONDRIAL transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, phosphate group as acceptor#GO:0016776;catalytic activity#GO:0003824;kinase activity#GO:0016301 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 nucleotide kinase#PC00172;kinase#PC00137 De novo purine biosynthesis#P02738>Adenylate kinase#P02896 CIOIN|Ensembl=ENSCING00000013203.2|UniProtKB=F6VT42 F6VT42 PTHR11829:SF384 FORKHEAD BOX PROTEIN FORK-HEAD DOMAIN-CONTAINING PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;anatomical structure morphogenesis#GO:0009653;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 CIOIN|Ensembl=ENSCING00000021823.1|UniProtKB=H2XPW5 H2XPW5 PTHR22957:SF497 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN ECOTROPIC VIRAL INTEGRATION SITE 5 ORTHOLOG nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 regulation of molecular function#GO:0065009;regulation of GTPase activity#GO:0043087;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;activation of GTPase activity#GO:0090630;biological regulation#GO:0065007;positive regulation of molecular function#GO:0044093;regulation of hydrolase activity#GO:0051336;regulation of catalytic activity#GO:0050790;positive regulation of hydrolase activity#GO:0051345 GTPase-activating protein#PC00257 CIOIN|Ensembl=ENSCING00000002123.3|UniProtKB=F6WRV9 F6WRV9 PTHR11136:SF5 FOLYLPOLYGLUTAMATE SYNTHASE-RELATED FOLYLPOLYGLUTAMATE SYNTHASE, MITOCHONDRIAL ligase activity#GO:0016874;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;folic acid-containing compound metabolic process#GO:0006760;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;heterocycle biosynthetic process#GO:0018130;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;cellular modified amino acid metabolic process#GO:0006575;aromatic compound biosynthetic process#GO:0019438;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ligase#PC00142;metabolite interconversion enzyme#PC00262 Formyltetrahydrofolate biosynthesis#P02743>Dihydrofolate synthase#P02958;Tetrahydrofolate biosynthesis#P02742>Dihydrofolate synthase#P02943 CIOIN|Ensembl=ENSCING00000007798.3|UniProtKB=F6WH66 F6WH66 PTHR11984:SF53 CONNEXIN GAP JUNCTION PROTEIN wide pore channel activity#GO:0022829;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;channel activity#GO:0015267 biological regulation#GO:0065007;regulation of biological process#GO:0050789;cell communication#GO:0007154;cellular process#GO:0009987;cell-cell signaling#GO:0007267;signaling#GO:0023052 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 cell junction protein#PC00070;gap junction#PC00105 CIOIN|Ensembl=ENSCING00000018394.1|UniProtKB=H2XX74 H2XX74 PTHR12419:SF7 OTU DOMAIN CONTAINING PROTEIN OTU DOMAIN-CONTAINING PROTEIN 3 cysteine-type peptidase activity#GO:0008234;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;cysteine-type deubiquitinase activity#GO:0004843 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;protein modification by small protein removal#GO:0070646;protein deubiquitination#GO:0016579;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cysteine protease#PC00081;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000018589.1|UniProtKB=H2XMU3 H2XMU3 PTHR46473:SF22 GH08155P ELRR (EXTRACELLULAR LEUCINE-RICH REPEAT) ONLY CIOIN|Ensembl=ENSCING00000013310.2|UniProtKB=F6ZGK8 F6ZGK8 PTHR48182:SF2 PROTEIN SERAC1 PROTEIN SERAC1 CIOIN|Ensembl=ENSCING00000009093.3|UniProtKB=F6QE47 F6QE47 PTHR10876:SF0 ZINC FINGER PROTEIN ZPR1 ZINC FINGER PROTEIN ZPR1 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000002357.3|UniProtKB=F6PJ79 F6PJ79 PTHR12482:SF67 LIPASE ROG1-RELATED-RELATED DUF676 DOMAIN-CONTAINING PROTEIN lipid metabolic process#GO:0006629;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular lipid metabolic process#GO:0044255;organic substance metabolic process#GO:0071704;primary metabolic process#GO:0044238;metabolic process#GO:0008152 CIOIN|Ensembl=ENSCING00000001565.3|UniProtKB=Q4H2J7 Q4H2J7 Ci-ZF(C2H2)-2 PTHR23235:SF170 KRUEPPEL-LIKE TRANSCRIPTION FACTOR FI01014P-RELATED sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 CIOIN|Ensembl=ENSCING00000020097.1|UniProtKB=H2XWA1 H2XWA1 PTHR10880:SF15 MORTALITY FACTOR 4-LIKE PROTEIN MSL COMPLEX SUBUNIT 3 histone acetyltransferase complex#GO:0000123;acetyltransferase complex#GO:1902493;protein-DNA complex#GO:0032993;chromatin#GO:0000785;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein acetyltransferase complex#GO:0031248;protein-containing complex#GO:0032991;chromosome#GO:0005694 chromatin/chromatin-binding, or -regulatory protein#PC00077 CIOIN|Ensembl=ENSCING00000008569.3|UniProtKB=F6X0I3 F6X0I3 adh3 PTHR43880:SF12 ALCOHOL DEHYDROGENASE ALCOHOL DEHYDROGENASE CLASS-3 cation binding#GO:0043169;small molecule binding#GO:0036094;zinc ion binding#GO:0008270;binding#GO:0005488;catalytic activity#GO:0003824;transition metal ion binding#GO:0046914;metal ion binding#GO:0046872;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;ion binding#GO:0043167;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;cellular metabolic process#GO:0044237;cellular process#GO:0009987;response to stimulus#GO:0050896;detoxification#GO:0098754;cellular response to oxygen-containing compound#GO:1901701;small molecule catabolic process#GO:0044282;response to chemical#GO:0042221;catabolic process#GO:0009056;response to toxic substance#GO:0009636;organic substance catabolic process#GO:1901575;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 dehydrogenase#PC00092;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000005648.3|UniProtKB=F6Y1Z7 F6Y1Z7 LOC100176070 PTHR23168:SF0 MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD1 MITOTIC ARREST DEFICIENT-LIKE PROTEIN 1 MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD1 negative regulation of sister chromatid segregation#GO:0033046;cellular localization#GO:0051641;regulation of mitotic nuclear division#GO:0007088;organelle localization#GO:0051640;regulation of chromosome segregation#GO:0051983;mitotic cell cycle checkpoint signaling#GO:0007093;nuclear division#GO:0000280;negative regulation of chromosome organization#GO:2001251;attachment of mitotic spindle microtubules to kinetochore#GO:0051315;negative regulation of mitotic nuclear division#GO:0045839;regulation of cellular component organization#GO:0051128;negative regulation of nuclear division#GO:0051784;negative regulation of mitotic sister chromatid segregation#GO:0033048;chromosome segregation#GO:0007059;regulation of biological process#GO:0050789;cell cycle checkpoint signaling#GO:0000075;mitotic cell cycle#GO:0000278;establishment of localization#GO:0051234;regulation of mitotic sister chromatid segregation#GO:0033047;attachment of spindle microtubules to kinetochore#GO:0008608;intracellular signal transduction#GO:0035556;negative regulation of cellular component organization#GO:0051129;establishment of organelle localization#GO:0051656;nuclear chromosome segregation#GO:0098813;sister chromatid segregation#GO:0000819;negative regulation of cell cycle#GO:0045786;regulation of mitotic cell cycle phase transition#GO:1901990;regulation of organelle organization#GO:0033043;mitotic spindle assembly checkpoint signaling#GO:0007094;negative regulation of chromosome segregation#GO:0051985;regulation of cell cycle phase transition#GO:1901987;cellular component organization#GO:0016043;cell communication#GO:0007154;regulation of mitotic metaphase/anaphase transition#GO:0030071;regulation of cell cycle process#GO:0010564;cellular component organization or biogenesis#GO:0071840;mitotic metaphase chromosome alignment#GO:0007080;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;chromosome localization#GO:0050000;negative regulation of metaphase/anaphase transition of cell cycle#GO:1902100;negative regulation of mitotic sister chromatid separation#GO:2000816;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;negative regulation of mitotic metaphase/anaphase transition#GO:0045841;regulation of chromosome separation#GO:1905818;cell cycle process#GO:0022402;negative regulation of cell cycle process#GO:0010948;mitotic cell cycle process#GO:1903047;negative regulation of mitotic cell cycle phase transition#GO:1901991;negative regulation of organelle organization#GO:0010639;mitotic nuclear division#GO:0140014;mitotic sister chromatid segregation#GO:0000070;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;regulation of chromosome organization#GO:0033044;cellular response to stimulus#GO:0051716;regulation of mitotic sister chromatid separation#GO:0010965;regulation of nuclear division#GO:0051783;establishment of chromosome localization#GO:0051303;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of mitotic cell cycle#GO:0045930;cellular process#GO:0009987;localization#GO:0051179;response to stimulus#GO:0050896;negative regulation of chromosome separation#GO:1905819;organelle organization#GO:0006996;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;establishment of localization in cell#GO:0051649;organelle fission#GO:0048285;regulation of sister chromatid segregation#GO:0033045;regulation of mitotic cell cycle#GO:0007346;metaphase chromosome alignment#GO:0051310 envelope#GO:0031975;supramolecular complex#GO:0099080;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;kinetochore#GO:0000776;nuclear envelope#GO:0005635;condensed chromosome, centromeric region#GO:0000779;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;cellular anatomical entity#GO:0110165;organelle#GO:0043226;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;endomembrane system#GO:0012505;mitotic spindle#GO:0072686;chromosome#GO:0005694;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;chromosomal region#GO:0098687;cytoskeleton#GO:0005856;spindle#GO:0005819 CIOIN|Ensembl=ENSCING00000013763.2|UniProtKB=F6RK63 F6RK63 LOC100185027 PTHR43675:SF8 ARSENITE METHYLTRANSFERASE ARSENITE METHYLTRANSFERASE methyltransferase activity#GO:0008168;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824 methyltransferase#PC00155;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000004055.3|UniProtKB=F7B7B5 F7B7B5 PTHR24064:SF577 SOLUTE CARRIER FAMILY 22 MEMBER GH09241P secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000016102.2|UniProtKB=F7BHN2 F7BHN2 PTHR16560:SF2 ALPHA-2-MACROGLOBULIN RECEPTOR-ASSOCIATED PROTEIN ALPHA-2-MACROGLOBULIN RECEPTOR-ASSOCIATED PROTEIN regulation of biological process#GO:0050789;regulation of endocytosis#GO:0030100;regulation of transport#GO:0051049;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of localization#GO:0032879;regulation of cellular component organization#GO:0051128;regulation of vesicle-mediated transport#GO:0060627;regulation of receptor-mediated endocytosis#GO:0048259 cellular anatomical entity#GO:0110165;endomembrane system#GO:0012505 chaperone#PC00072 CIOIN|Ensembl=ENSCING00000010642.3|UniProtKB=F6TM93 F6TM93 PTHR12062:SF0 N-ACETYLGLUCOSAMINYLTRANSFERASE VI ALPHA-1,3-MANNOSYL-GLYCOPROTEIN 4-BETA-N-ACETYLGLUCOSAMINYLTRANSFERASE B acetylglucosaminyltransferase activity#GO:0008375;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;UDP-glycosyltransferase activity#GO:0008194 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein N-linked glycosylation#GO:0006487;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000006950.3|UniProtKB=F6UZS7 F6UZS7 LOC100181104 PTHR11728:SF8 GLYCEROL-3-PHOSPHATE DEHYDROGENASE GLYCEROL-3-PHOSPHATE DEHYDROGENASE [NAD(+)]-RELATED oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;carbohydrate derivative metabolic process#GO:1901135;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;pyridine nucleotide metabolic process#GO:0019362;nicotinamide nucleotide metabolic process#GO:0046496;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;glycerol-3-phosphate metabolic process#GO:0006072;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;pyridine-containing compound metabolic process#GO:0072524;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;purine nucleotide metabolic process#GO:0006163;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 dehydrogenase#PC00092;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000004637.3|UniProtKB=F6PTF9 F6PTF9 PTHR14611:SF2 TECTONIC FAMILY MEMBER TECTONIC CIOIN|Ensembl=ENSCING00000014827.2|UniProtKB=F6S959 F6S959 PTHR11711:SF30 ADP RIBOSYLATION FACTOR-RELATED ADP-RIBOSYLATION FACTOR 1 carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;anion binding#GO:0043168 cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 G-protein#PC00020 Integrin signalling pathway#P00034>Arf1#P00923;Huntington disease#P00029>ARF#P00786 CIOIN|Ensembl=ENSCING00000022413.1|UniProtKB=H2XLU5 H2XLU5 PTHR45742:SF8 COMPLEMENT COMPONENT C6 FLOCCULATION PROTEIN FLO11 complement component#PC00078 CIOIN|Ensembl=ENSCING00000002701.3|UniProtKB=F6UE50 F6UE50 PTHR46452:SF1 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 3 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 3 protein binding#GO:0005515;transcription factor binding#GO:0008134;binding#GO:0005488 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of RNA metabolic process#GO:0051254;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;DNA-directed RNA polymerase complex#GO:0000428;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;transcription factor TFIID complex#GO:0005669;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695;RNA polymerase II, holoenzyme#GO:0016591;RNA polymerase complex#GO:0030880;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 CIOIN|Ensembl=ENSCING00000023363.1|UniProtKB=H2XQ46 H2XQ46 LOC100180134 PTHR11214:SF346 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE HEXOSYLTRANSFERASE transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;protein O-linked glycosylation#GO:0006493;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 bounding membrane of organelle#GO:0098588;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;Golgi membrane#GO:0000139;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111 CIOIN|Ensembl=ENSCING00000019406.1|UniProtKB=H2XX53 H2XX53 PTHR12241:SF39 TUBULIN POLYGLUTAMYLASE TUBULIN POLYGLUTAMYLASE TTLL9-RELATED cytoskeletal protein binding#GO:0008092;ligase activity#GO:0016874;protein binding#GO:0005515;tubulin binding#GO:0015631;catalytic activity, acting on a protein#GO:0140096;binding#GO:0005488;catalytic activity#GO:0003824 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;microtubule cytoskeleton organization#GO:0000226;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;cellular component organization#GO:0016043;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;nitrogen compound metabolic process#GO:0006807;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;microtubule cytoskeleton#GO:0015630;ciliary basal body#GO:0036064;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;cilium#GO:0005929;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;microtubule or microtubule-binding cytoskeletal protein#PC00157 CIOIN|Ensembl=ENSCING00000013151.2|UniProtKB=F6YYA5 F6YYA5 PTHR12729:SF6 TRNA(HIS) GUANYLYLTRANSFERASE-RELATED TRNA(HIS) GUANYLYLTRANSFERASE-RELATED catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on RNA#GO:0140098;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;tRNA metabolic process#GO:0006399;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 CIOIN|Ensembl=ENSCING00000003553.3|UniProtKB=F6YTM1 F6YTM1 PTHR43867:SF2 CELLULOSE SYNTHASE CATALYTIC SUBUNIT A [UDP-FORMING] CELLULOSE SYNTHASE CATALYTIC SUBUNIT A [UDP-FORMING] CIOIN|Ensembl=ENSCING00000013628.2|UniProtKB=F7B6X2 F7B6X2 LOC100179718 PTHR19282:SF544 TETRASPANIN TETRASPANIN cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000002933.3|UniProtKB=F7BIX8 F7BIX8 PTHR23317:SF26 DEDICATOR OF CYTOKINESIS DOCK ZIZIMIN, ISOFORM K nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 regulation of molecular function#GO:0065009;regulation of GTPase activity#GO:0043087;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;biological regulation#GO:0065007;positive regulation of molecular function#GO:0044093;regulation of hydrolase activity#GO:0051336;regulation of catalytic activity#GO:0050790;positive regulation of hydrolase activity#GO:0051345 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022 CIOIN|Ensembl=ENSCING00000021274.1|UniProtKB=H2XXY6 H2XXY6 PTHR13452:SF10 THUMP DOMAIN CONTAINING PROTEIN 1-RELATED THUMP DOMAIN-CONTAINING PROTEIN 1 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;tRNA metabolic process#GO:0006399;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;RNA modification#GO:0009451;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;tRNA modification#GO:0006400;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 CIOIN|Ensembl=ENSCING00000018599.1|UniProtKB=H2XTR9 H2XTR9 PTHR30289:SF8 UNCHARACTERIZED PROTEIN YBCL-RELATED YHYH DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000006216.3|UniProtKB=F6YW68 F6YW68 PTHR10668:SF103 PHYTOENE DEHYDROGENASE PYRIDINE NUCLEOTIDE-DISULFIDE OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN 2 dehydrogenase#PC00092;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000012508.1|UniProtKB=F7BE99 F7BE99 PTHR10924:SF4 MAJOR FACILITATOR SUPERFAMILY PROTEIN-RELATED GH15861P tetrapyrrole binding#GO:0046906;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;binding#GO:0005488;organic cyclic compound binding#GO:0097159;heme binding#GO:0020037 localization#GO:0051179;organic substance transport#GO:0071702;metal ion transport#GO:0030001;establishment of localization#GO:0051234;transport#GO:0006810;monoatomic cation transport#GO:0006812;nitrogen compound transport#GO:0071705;iron ion transport#GO:0006826;transition metal ion transport#GO:0000041;monoatomic ion transport#GO:0006811 cellular anatomical entity#GO:0110165;membrane#GO:0016020 secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000014336.2|UniProtKB=F6TZA0 F6TZA0 PTHR12461:SF53 HYPOXIA-INDUCIBLE FACTOR 1 ALPHA INHIBITOR-RELATED JMJC DOMAIN-CONTAINING PROTEIN protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000007894.3|UniProtKB=F6STU7 F6STU7 LOC100181475 PTHR21231:SF3 XPA-BINDING PROTEIN 1-RELATED GPN-LOOP GTPASE 2 hydrolase activity#GO:0016787;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 small GTPase#PC00208;G-protein#PC00020;protein-binding activity modulator#PC00095 CIOIN|Ensembl=ENSCING00000004719.3|UniProtKB=H2XU65 H2XU65 PTHR21321:SF1 PNAS-3 RELATED EXOSOME COMPLEX COMPONENT RRP40 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159 negative regulation of gene expression#GO:0010629;tRNA metabolic process#GO:0006399;cellular component biogenesis#GO:0044085;regulation of catabolic process#GO:0009894;heterocycle catabolic process#GO:0046700;regulation of nitrogen compound metabolic process#GO:0051171;rRNA processing#GO:0006364;positive regulation of cellular metabolic process#GO:0031325;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;RNA destabilization#GO:0050779;modification-dependent macromolecule catabolic process#GO:0043632;regulation of biological process#GO:0050789;ncRNA metabolic process#GO:0034660;mRNA metabolic process#GO:0016071;regulation of biological quality#GO:0065008;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;snRNA 3'-end processing#GO:0034472;ribosome biogenesis#GO:0042254;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;regulation of RNA stability#GO:0043487;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;positive regulation of mRNA catabolic process#GO:0061014;regulation of cellular process#GO:0050794;rRNA metabolic process#GO:0016072;post-transcriptional regulation of gene expression#GO:0010608;positive regulation of catabolic process#GO:0009896;mRNA destabilization#GO:0061157;nucleobase-containing compound catabolic process#GO:0034655;polyadenylation-dependent ncRNA catabolic process#GO:0043634;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of mRNA stability#GO:0043488;regulation of mRNA catabolic process#GO:0061013;RNA metabolic process#GO:0016070;positive regulation of cellular catabolic process#GO:0031331;RNA processing#GO:0006396;biosynthetic process#GO:0009058;cellular nitrogen compound catabolic process#GO:0044270;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;mRNA catabolic process#GO:0006402;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;snRNA processing#GO:0016180;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance catabolic process#GO:1901575;maturation of 5.8S rRNA#GO:0000460;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;positive regulation of mRNA metabolic process#GO:1903313;heterocycle metabolic process#GO:0046483;snRNA metabolic process#GO:0016073;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;RNA 3'-end processing#GO:0031123;cellular biosynthetic process#GO:0044249;nuclear-transcribed mRNA catabolic process#GO:0000956;organic substance biosynthetic process#GO:1901576;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;aromatic compound catabolic process#GO:0019439;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;ribonucleoprotein complex biogenesis#GO:0022613;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;positive regulation of RNA metabolic process#GO:0051254 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513;exosome (RNase complex)#GO:0000178 RNA processing factor#PC00147 CIOIN|Ensembl=ENSCING00000021738.1|UniProtKB=H2XTW7 H2XTW7 LOC100184867 PTHR28556:SF4 TRANSMEMBRANE PROTEIN 106B TRANSMEMBRANE PROTEIN 106A CIOIN|Ensembl=ENSCING00000001933.3|UniProtKB=F6YFM8 F6YFM8 PTHR23505:SF79 SPINSTER PROTEIN SPINSTER cellular anatomical entity#GO:0110165;membrane#GO:0016020 transporter#PC00227 CIOIN|Ensembl=ENSCING00000014768.2|UniProtKB=F6ZTE7 F6ZTE7 PTHR28441:SF2 PROTEIN FAM91A1 PROTEIN FAM91A1 CIOIN|Ensembl=ENSCING00000003768.3|UniProtKB=F7AW67 F7AW67 LOC100182745 PTHR19850:SF25 GUANINE NUCLEOTIDE-BINDING PROTEIN BETA G PROTEIN BETA GUANINE NUCLEOTIDE-BINDING PROTEIN SUBUNIT BETA-1 molecular adaptor activity#GO:0060090;signaling adaptor activity#GO:0035591;signaling receptor complex adaptor activity#GO:0030159;protein-macromolecule adaptor activity#GO:0030674 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cytoplasm#GO:0005737;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;plasma membrane protein complex#GO:0098797;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;cytoplasmic side of plasma membrane#GO:0009898;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886;extrinsic component of membrane#GO:0019898 heterotrimeric G-protein#PC00117;G-protein#PC00020 5HT1 type receptor mediated signaling pathway#P04373>G-protein#P04408;5HT4 type receptor mediated signaling pathway#P04376>G-protein#P04430;Histamine H2 receptor mediated signaling pathway#P04386>G-Protein#P04490;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>G-Protein#P01073;Thyrotropin-releasing hormone receptor signaling pathway#P04394>G-Protein#P04584;Beta1 adrenergic receptor signaling pathway#P04377>G-Protein#P04436;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Gbeta#P00710;Oxytocin receptor mediated signaling pathway#P04391>G-Protein#P04534;Histamine H1 receptor mediated signaling pathway#P04385>G-Protein#P04488;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>G-Protein#P01085;5HT2 type receptor mediated signaling pathway#P04374>G-protein#P04416;Opioid prodynorphin pathway#P05916>G-protein#P06002;Metabotropic glutamate receptor group III pathway#P00039>G-Protein#P01045;Cortocotropin releasing factor receptor signaling pathway#P04380>G-Protein#P04458;Wnt signaling pathway#P00057>GBeta#P01457;Metabotropic glutamate receptor group II pathway#P00040>G-protein#P01047;Enkephalin release#P05913>G-Protein (i)#P05974;PI3 kinase pathway#P00048>Gbetagamma#P01188;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Gbeta#P00727;Enkephalin release#P05913>G-Protein (s)#P05977;Opioid proenkephalin pathway#P05915>G-protein#P05994;Beta3 adrenergic receptor signaling pathway#P04379>G-Protein#P04448;Opioid proopiomelanocortin pathway#P05917>G-protein#P06012;Beta2 adrenergic receptor signaling pathway#P04378>G-Protein#P04443;Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Gbeta#P00753 CIOIN|Ensembl=ENSCING00000020615.1|UniProtKB=H2XM22 H2XM22 LOC100187016 PTHR12388:SF0 MITOCHONDRIA ASSOCIATED GRANULOCYTE MACROPHAGE CSF SIGNALING MOLECULE MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM16 cellular localization#GO:0051641;transmembrane transport#GO:0055085;macromolecule localization#GO:0033036;transport#GO:0006810;protein transmembrane transport#GO:0071806;protein targeting#GO:0006605;nitrogen compound transport#GO:0071705;establishment of protein localization to organelle#GO:0072594;protein localization to mitochondrion#GO:0070585;cellular process#GO:0009987;protein transmembrane import into intracellular organelle#GO:0044743;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;mitochondrial transport#GO:0006839;organic substance transport#GO:0071702;protein import into mitochondrial matrix#GO:0030150;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein targeting to mitochondrion#GO:0006626;establishment of protein localization to mitochondrion#GO:0072655;protein transport#GO:0015031;protein localization to organelle#GO:0033365;mitochondrial transmembrane transport#GO:1990542 envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;TIM23 mitochondrial import inner membrane translocase complex#GO:0005744;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial envelope#GO:0005740;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227;mitochondrial protein-containing complex#GO:0098798 transporter#PC00227 CIOIN|Ensembl=ENSCING00000015952.2|UniProtKB=F6XI30 F6XI30 PTHR24251:SF30 OVOCHYMASE-RELATED MEMBRANE FRIZZLED-RELATED PROTEIN serine protease#PC00203;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000011594.2|UniProtKB=F6S1R7 F6S1R7 PTHR18860:SF159 14-3-3 PROTEIN 14-3-3 PROTEIN ZETA localization#GO:0051179;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular localization#GO:0051641;cellular response to stimulus#GO:0051716;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052;protein localization#GO:0008104 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 Parkinson disease#P00049>14-3-3#P01238;FGF signaling pathway#P00021>14-3-3#P00624;EGF receptor signaling pathway#P00018>14-3-3#P00539;PI3 kinase pathway#P00048>14-3-3#P01206 CIOIN|Ensembl=ENSCING00000005199.3|UniProtKB=F6Z1E3 F6Z1E3 LOC100183027 PTHR11830:SF0 40S RIBOSOMAL PROTEIN S3A SMALL RIBOSOMAL SUBUNIT PROTEIN ES1 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202 CIOIN|Ensembl=ENSCING00000015300.2|UniProtKB=A0A1W5BGT3 A0A1W5BGT3 LOC100179196 PTHR46468:SF1 SENTRIN-SPECIFIC PROTEASE 8 SENTRIN-SPECIFIC PROTEASE 8 hydrolase activity#GO:0016787;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;protein modification by small protein removal#GO:0070646;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;post-translational protein modification#GO:0043687;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 protease#PC00190 CIOIN|Ensembl=ENSCING00000004664.3|UniProtKB=F6RPI4 F6RPI4 LOC100175937 PTHR43115:SF4 DEHYDROGENASE/REDUCTASE SDR FAMILY MEMBER 11 DEHYDROGENASE_REDUCTASE SDR FAMILY MEMBER 11 oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000018091.1|UniProtKB=F6YQI1 F6YQI1 PTHR20855:SF15 ADIPOR/PROGESTIN RECEPTOR-RELATED PROGESTIN AND ADIPOQ RECEPTOR FAMILY MEMBER 3 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 G-protein coupled receptor#PC00021 CIOIN|Ensembl=ENSCING00000009295.3|UniProtKB=Q86SD3 Q86SD3 Ci-betaTrCP PTHR14604:SF4 WD40 REPEAT PF20 F-BOX DOMAIN-CONTAINING PROTEIN microtubule or microtubule-binding cytoskeletal protein#PC00157 Hedgehog signaling pathway#P00025>Slimb#P00683;Wnt signaling pathway#P00057>betaTrCP#P01454 CIOIN|Ensembl=ENSCING00000024996.1|UniProtKB=H2XXW5 H2XXW5 PTHR13809:SF27 GUANINE NUCLEOTIDE-BINDING PROTEIN GAMMA SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN SUBUNIT GAMMA protein binding#GO:0005515;binding#GO:0005488 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;plasma membrane protein complex#GO:0098797;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;cytoplasmic side of plasma membrane#GO:0009898;extrinsic component of membrane#GO:0019898;plasma membrane#GO:0005886 heterotrimeric G-protein#PC00117;G-protein#PC00020 Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>G-Protein#P01085;5HT2 type receptor mediated signaling pathway#P04374>G-protein#P04416;Cortocotropin releasing factor receptor signaling pathway#P04380>G-Protein#P04458;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>G-Protein#P01073;Metabotropic glutamate receptor group II pathway#P00040>G-protein#P01047 CIOIN|Ensembl=ENSCING00000020532.1|UniProtKB=H2XRG9 H2XRG9 PTHR31397:SF1 BLOC-1-RELATED COMPLEX SUBUNIT 7 BORSC7 BLOC-1-RELATED COMPLEX SUBUNIT 7 intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991 CIOIN|Ensembl=ENSCING00000004957.3|UniProtKB=F6X9E5 F6X9E5 LOC100177120 PTHR23300:SF0 METHANETHIOL OXIDASE METHANETHIOL OXIDASE defense/immunity protein#PC00090 CIOIN|Ensembl=ENSCING00000001900.3|UniProtKB=F6TEQ0 F6TEQ0 LOC100185283 PTHR24070:SF258 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY RAS-RELATED PROTEIN RAL-A GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;ion binding#GO:0043167;anion binding#GO:0043168 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 small GTPase#PC00208;G-protein#PC00020 Ras Pathway#P04393>Ral#P04550 CIOIN|Ensembl=ENSCING00000013502.2|UniProtKB=F7B1S6 F7B1S6 PTHR24088:SF0 28S RIBOSOMAL PROTEIN S17, MITOCHONDRIAL SMALL RIBOSOMAL SUBUNIT PROTEIN US17M structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;mitochondrial gene expression#GO:0140053;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;mitochondrial translation#GO:0032543;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;mitochondrial ribosome#GO:0005761;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;ribosomal subunit#GO:0044391;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;organellar ribosome#GO:0000313;protein-containing complex#GO:0032991;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;small ribosomal subunit#GO:0015935;ribosome#GO:0005840;mitochondrial small ribosomal subunit#GO:0005763;mitochondrial protein-containing complex#GO:0098798 ribosomal protein#PC00202;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000004224.3|UniProtKB=F6YGM8 F6YGM8 PTHR15921:SF7 PRE-MRNA CLEAVAGE COMPLEX II SR-RELATED AND CTD-ASSOCIATED FACTOR 8 nucleic acid binding#GO:0003676;basal RNA polymerase II transcription machinery binding#GO:0001099;RNA binding#GO:0003723;RNA polymerase binding#GO:0070063;binding#GO:0005488;organic cyclic compound binding#GO:0097159;RNA polymerase core enzyme binding#GO:0043175;RNA polymerase II complex binding#GO:0000993;enzyme binding#GO:0019899;protein binding#GO:0005515;mRNA binding#GO:0003729;basal transcription machinery binding#GO:0001098 cellular aromatic compound metabolic process#GO:0006725;DNA-templated transcription#GO:0006351;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;RNA biosynthetic process#GO:0032774;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;aromatic compound biosynthetic process#GO:0019438;transcription by RNA polymerase II#GO:0006366;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;mRNA cleavage factor complex#GO:0005849;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA processing factor#PC00147;RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000004692.3|UniProtKB=F6QNH2 F6QNH2 LOC100185271 PTHR35826:SF1 PROTEIN ATP6V1FNB-LIKE PROTEIN ATP6V1FNB-LIKE CIOIN|Ensembl=ENSCING00000018890.1|UniProtKB=H2XP14 H2XP14 LOC113474176 PTHR13511:SF0 KXDL MOTIF-CONTAINING PROTEIN 1 KXDL MOTIF-CONTAINING PROTEIN 1 lysosome localization#GO:0032418;localization#GO:0051179;organelle localization#GO:0051640 intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991 CIOIN|Ensembl=ENSCING00000008579.3|UniProtKB=F6X056 F6X056 PTHR13743:SF162 BEIGE/BEACH-RELATED NEUROBEACHIN enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;binding#GO:0005488;kinase binding#GO:0019900 localization#GO:0051179;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;cellular process#GO:0009987;macromolecule localization#GO:0033036;protein localization#GO:0008104 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;membrane#GO:0016020;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000012194.2|UniProtKB=F6TTX9 F6TTX9 PTHR45712:SF26 AGAP008170-PA LRRNT DOMAIN-CONTAINING PROTEIN extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 CIOIN|Ensembl=ENSCING00000009074.3|UniProtKB=F6QIM1 F6QIM1 LOC101242578 PTHR23050:SF23 CALCIUM BINDING PROTEIN AT22559P-RELATED cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488 microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cellular process#GO:0009987;microtubule-based process#GO:0007017;organelle organization#GO:0006996 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;centriole#GO:0005814;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 calmodulin-related#PC00061 CIOIN|Ensembl=ENSCING00000005139.3|UniProtKB=F6VBD0 F6VBD0 PTHR12546:SF60 FER-1-LIKE MISFIRE, ISOFORM F endomembrane system organization#GO:0010256;cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;cellular process#GO:0009987;membrane organization#GO:0061024;plasma membrane organization#GO:0007009 membrane trafficking regulatory protein#PC00151 CIOIN|Ensembl=ENSCING00000024855.1|UniProtKB=H2Y1A4 H2Y1A4 LOC100175912 PTHR32026:SF10 METHYLTRANSFERASE-LIKE PROTEIN 24 METHYLTRANSFERASE-LIKE PROTEIN 24-RELATED methyltransferase#PC00155 CIOIN|Ensembl=ENSCING00000007577.3|UniProtKB=F7A4H3 F7A4H3 PTHR10030:SF37 ALPHA-L-FUCOSIDASE ALPHA-L-FUCOSIDASE-RELATED hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 monosaccharide metabolic process#GO:0005996;carbohydrate derivative metabolic process#GO:1901135;glycosyl compound catabolic process#GO:1901658;carbohydrate derivative catabolic process#GO:1901136;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;hexose metabolic process#GO:0019318;glycosyl compound metabolic process#GO:1901657;carbohydrate metabolic process#GO:0005975;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;lysosome#GO:0005764;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;lytic vacuole#GO:0000323;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosidase#PC00110;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000013718.2|UniProtKB=F6PMQ9 F6PMQ9 PTHR34349:SF1 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 32 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 32 phosphatase binding#GO:0019902;enzyme binding#GO:0019899;protein binding#GO:0005515;binding#GO:0005488 protein-binding activity modulator#PC00095;phosphatase modulator#PC00184 CIOIN|Ensembl=ENSCING00000006542.3|UniProtKB=H2XSL3 H2XSL3 PTHR21497:SF39 UBIQUITIN LIGASE E3 ALPHA-RELATED E3 UBIQUITIN-PROTEIN LIGASE UBR3 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000003926.3|UniProtKB=F7A5D0 F7A5D0 cirgg1 PTHR23236:SF119 EUKARYOTIC TRANSLATION INITIATION FACTOR 4B/4H NUCLEAR RNA-BINDING PROTEIN SART-3 translation initiation factor#PC00224;translation factor#PC00223 CIOIN|Ensembl=ENSCING00000011708.1|UniProtKB=F6WLI7 F6WLI7 PTHR32026:SF10 METHYLTRANSFERASE-LIKE PROTEIN 24 METHYLTRANSFERASE-LIKE PROTEIN 24-RELATED methyltransferase#PC00155 CIOIN|Ensembl=ENSCING00000000283.3|UniProtKB=F6PR32 F6PR32 PTHR10218:SF302 GTP-BINDING PROTEIN ALPHA SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN ALPHA-5 SUBUNIT GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;ribonucleoside triphosphate phosphatase activity#GO:0017111;G protein-coupled receptor binding#GO:0001664;signaling receptor binding#GO:0005102 regulation of biological process#GO:0050789;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cytoplasm#GO:0005737;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;cytoplasmic side of plasma membrane#GO:0009898;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622;extrinsic component of membrane#GO:0019898 heterotrimeric G-protein#PC00117;G-protein#PC00020 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Galphai#P00828;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Galphai/q#P00873 CIOIN|Ensembl=ENSCING00000005042.3|UniProtKB=F6SM85 F6SM85 LOC100181882 PTHR12363:SF42 TRANSPORTIN 3 AND IMPORTIN 13 TRANSPORTIN-3 cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;protein localization to nucleus#GO:0034504;nitrogen compound transport#GO:0071705;establishment of protein localization to organelle#GO:0072594;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;protein import into nucleus#GO:0006606;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;protein localization to organelle#GO:0033365;nuclear transport#GO:0051169;import into nucleus#GO:0051170 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 transporter#PC00227 CIOIN|Ensembl=ENSCING00000012876.2|UniProtKB=F6PHT6 F6PHT6 PTHR22829:SF5 DEP DOMAIN PROTEIN INTEGRAL MEMBRANE PROTEIN GPR155 regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;negative regulation of response to stimulus#GO:0048585;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;regulation of BMP signaling pathway#GO:0030510;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;negative regulation of BMP signaling pathway#GO:0030514;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cellular response to growth factor stimulus#GO:0090287;negative regulation of signal transduction#GO:0009968;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 CIOIN|Ensembl=ENSCING00000006449.3|UniProtKB=F6QKL4 F6QKL4 PTHR11211:SF40 IROQUOIS-CLASS HOMEODOMAIN PROTEIN IRX MIRROR, ISOFORM C sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;neurogenesis#GO:0022008;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;multicellular organism development#GO:0007275;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell development#GO:0048468;system development#GO:0048731;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;neuron differentiation#GO:0030182;multicellular organismal process#GO:0032501;regulation of macromolecule biosynthetic process#GO:0010556;generation of neurons#GO:0048699;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 CIOIN|Ensembl=ENSCING00000017044.2|UniProtKB=F6X329 F6X329 PTHR11783:SF274 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4A1 sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824 cellular metabolic process#GO:0044237;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000023431.1|UniProtKB=H2XK79 H2XK79 PTHR45635:SF14 ADP,ATP CARRIER PROTEIN 1-RELATED-RELATED ADP_ATP TRANSLOCASE transfer/carrier protein#PC00219 CIOIN|Ensembl=ENSCING00000002352.3|UniProtKB=F6PJI0 F6PJI0 PTHR24082:SF473 NUCLEAR HORMONE RECEPTOR ECDYSONE-INDUCED PROTEIN 75B, ISOFORM B cis-regulatory region sequence-specific DNA binding#GO:0000987;signaling receptor activity#GO:0038023;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular transducer activity#GO:0060089;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of nitrogen compound metabolic process#GO:0051173;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;signal transduction#GO:0007165;positive regulation of RNA biosynthetic process#GO:1902680;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;hormone-mediated signaling pathway#GO:0009755;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;positive regulation of biosynthetic process#GO:0009891;response to endogenous stimulus#GO:0009719;cellular response to hormone stimulus#GO:0032870;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;positive regulation of biological process#GO:0048518;negative regulation of cellular process#GO:0048523;signaling#GO:0023052;response to organic substance#GO:0010033;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;cellular response to endogenous stimulus#GO:0071495;negative regulation of biosynthetic process#GO:0009890;cellular response to chemical stimulus#GO:0070887;regulation of DNA-templated transcription#GO:0006355;cellular response to organic substance#GO:0071310;negative regulation of metabolic process#GO:0009892;cell communication#GO:0007154;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;negative regulation of nitrogen compound metabolic process#GO:0051172;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;negative regulation of macromolecule biosynthetic process#GO:0010558;response to hormone#GO:0009725;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;response to chemical#GO:0042221;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;positive regulation of RNA metabolic process#GO:0051254;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 C4 zinc finger nuclear receptor#PC00169;zinc finger transcription factor#PC00244 CIOIN|Ensembl=ENSCING00000012056.2|UniProtKB=F6Z0X9 F6Z0X9 LOC100178773 PTHR24104:SF57 E3 UBIQUITIN-PROTEIN LIGASE NHLRC1-RELATED BEE-MILK PROTEIN transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein polyubiquitination#GO:0000209;proteasomal protein catabolic process#GO:0010498;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000005430.3|UniProtKB=F6YQ66 F6YQ66 PTHR24251:SF28 OVOCHYMASE-RELATED NEUROPILIN AND TOLLOID-LIKE, ISOFORM B serine protease#PC00203;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000002929.3|UniProtKB=F6R8H4 F6R8H4 LOC100185664 PTHR48099:SF5 C-1-TETRAHYDROFOLATE SYNTHASE, CYTOPLASMIC-RELATED C-1-TETRAHYDROFOLATE SYNTHASE, CYTOPLASMIC hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular modified amino acid metabolic process#GO:0006575;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;folic acid-containing compound metabolic process#GO:0006760;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262 Formyltetrahydrofolate biosynthesis#P02743>Methylene tetrahydrofolate dehydrogenase#P02952 CIOIN|Ensembl=ENSCING00000017067.2|UniProtKB=F7A2G6 F7A2G6 KYNU PTHR14084:SF0 KYNURENINASE KYNURENINASE hydrolase activity#GO:0016787;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;heterocycle catabolic process#GO:0046700;biogenic amine metabolic process#GO:0006576;organonitrogen compound catabolic process#GO:1901565;cellular nitrogen compound catabolic process#GO:0044270;amino acid catabolic process#GO:0009063;organic cyclic compound metabolic process#GO:1901360;aromatic amino acid metabolic process#GO:0009072;nitrogen compound metabolic process#GO:0006807;alpha-amino acid metabolic process#GO:1901605;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248;heterocycle metabolic process#GO:0046483;amine metabolic process#GO:0009308;oxoacid metabolic process#GO:0043436;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;aromatic compound catabolic process#GO:0019439;organic cyclic compound catabolic process#GO:1901361;aromatic amino acid family catabolic process#GO:0009074;carboxylic acid metabolic process#GO:0019752;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000004154.3|UniProtKB=F6TUF1 F6TUF1 PTHR19325:SF560 COMPLEMENT COMPONENT-RELATED SUSHI DOMAIN-CONTAINING SUSHI, VON WILLEBRAND FACTOR TYPE A, EGF AND PENTRAXIN DOMAIN-CONTAINING PROTEIN 1 complement component#PC00078 CIOIN|Ensembl=ENSCING00000023081.1|UniProtKB=H2XL87 H2XL87 LOC100185850 PTHR24073:SF212 DRAB5-RELATED FI01544P GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824 localization#GO:0051179;organic substance transport#GO:0071702;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;transport#GO:0006810;protein transport#GO:0015031;nitrogen compound transport#GO:0071705;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104 cellular anatomical entity#GO:0110165;endomembrane system#GO:0012505 small GTPase#PC00208;G-protein#PC00020 CIOIN|Ensembl=ENSCING00000018829.1|UniProtKB=H2XXI7 H2XXI7 PTHR12674:SF2 PREFOLDIN SUBUNIT 5 PREFOLDIN SUBUNIT 5 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 chaperone#PC00072 CIOIN|Ensembl=ENSCING00000025099.1|UniProtKB=H2XS77 H2XS77 PTHR43975:SF2 ZGC:101858 EG:BACR7A4.14 PROTEIN-RELATED CIOIN|Ensembl=ENSCING00000013204.2|UniProtKB=F6VT35 F6VT35 PTHR11829:SF384 FORKHEAD BOX PROTEIN FORK-HEAD DOMAIN-CONTAINING PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;anatomical structure morphogenesis#GO:0009653;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 CIOIN|Ensembl=ENSCING00000007833.3|UniProtKB=F6WTN3 F6WTN3 LOC100179294 PTHR35845:SF1 SPERMATOGENESIS-ASSOCIATED SERINE-RICH PROTEIN 1 SPERMATOGENESIS-ASSOCIATED SERINE-RICH PROTEIN 1 CIOIN|Ensembl=ENSCING00000000082.3|UniProtKB=F6TS99 F6TS99 LOC100180323 PTHR12011:SF471 ADHESION G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 2 PROFILE 2 DOMAIN-CONTAINING PROTEIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 CIOIN|Ensembl=ENSCING00000021871.1|UniProtKB=H2XVG6 H2XVG6 LOC100179155 PTHR34174:SF1 HYDROLETHALUS SYNDROME PROTEIN 1 CENTRIOLAR AND CILIOGENESIS-ASSOCIATED PROTEIN HYLS1 organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cell projection organization#GO:0030030;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;non-motile cilium#GO:0097730;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;centriole#GO:0005814;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cilium#GO:0005929;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000019886.1|UniProtKB=H2Y219 H2Y219 PTHR22306:SF2 CHROMOSOME 7 OPEN READING FRAME 50 CHROMOSOME 7 OPEN READING FRAME 50 CIOIN|Ensembl=ENSCING00000021802.1|UniProtKB=H2Y3N3 H2Y3N3 PTHR22618:SF2 PROTEIN O-MANNOSE KINASE PROTEIN O-MANNOSE KINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;carbohydrate kinase activity#GO:0019200;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate phosphorylation#GO:0046835;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;protein O-linked glycosylation#GO:0006493;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;carbohydrate metabolic process#GO:0005975;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000006743.3|UniProtKB=F6VET4 F6VET4 LOC100187395 PTHR24096:SF149 LONG-CHAIN-FATTY-ACID--COA LIGASE AMP-BINDING DOMAIN-CONTAINING PROTEIN-RELATED ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877 metabolite interconversion enzyme#PC00262;ligase#PC00142 CIOIN|Ensembl=ENSCING00000018126.1|UniProtKB=H2XPJ6 H2XPJ6 PTHR13056:SF0 VACUOLAR FUSION PROTEIN CCZ1 HOMOLOG-RELATED VACUOLAR FUSION PROTEIN CCZ1 HOMOLOG-RELATED localization#GO:0051179;vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234;cellular process#GO:0009987;transport#GO:0006810 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000005043.3|UniProtKB=F7A4X2 F7A4X2 PTHR11749:SF3 RIBULOSE-5-PHOSPHATE-3-EPIMERASE RIBULOSE-PHOSPHATE 3-EPIMERASE cation binding#GO:0043169;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;metal ion binding#GO:0046872;racemase and epimerase activity, acting on carbohydrates and derivatives#GO:0016857;ion binding#GO:0043167;isomerase activity#GO:0016853 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;carbohydrate derivative metabolic process#GO:1901135;generation of precursor metabolites and energy#GO:0006091;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;pyridine nucleotide metabolic process#GO:0019362;nicotinamide nucleotide metabolic process#GO:0046496;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;glucose 6-phosphate metabolic process#GO:0051156;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;pyridine-containing compound metabolic process#GO:0072524;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;carbohydrate metabolic process#GO:0005975;NADP metabolic process#GO:0006739;purine nucleotide metabolic process#GO:0006163;small molecule metabolic process#GO:0044281;nucleobase-containing small molecule metabolic process#GO:0055086;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 Ascorbate degradation#P02729>L-xylulose-5-phosphate-3-epimerase#P02852 CIOIN|Ensembl=ENSCING00000009285.3|UniProtKB=Q4H3A1 Q4H3A1 Ci-Jun PTHR11462:SF35 JUN TRANSCRIPTION FACTOR-RELATED TRANSCRIPTION FACTOR JRA sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667 DNA-binding transcription factor#PC00218;basic leucine zipper transcription factor#PC00056 TGF-beta signaling pathway#P00052>Co-activators corepressors#P01282;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>AP-1#P00838 CIOIN|Ensembl=ENSCING00000000511.3|UniProtKB=F6VPZ1 F6VPZ1 LOC100185604 PTHR23162:SF10 OUTER DENSE FIBER OF SPERM TAILS 2 FI13205P regulation of biological process#GO:0050789;regulation of plasma membrane bounded cell projection assembly#GO:0120032;regulation of cellular component biogenesis#GO:0044087;regulation of cellular process#GO:0050794;regulation of organelle assembly#GO:1902115;regulation of organelle organization#GO:0033043;regulation of cell projection assembly#GO:0060491;regulation of cell projection organization#GO:0031344;biological regulation#GO:0065007;regulation of cellular component organization#GO:0051128;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of cilium assembly#GO:1902017 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000023118.1|UniProtKB=H2XNH4 H2XNH4 PTHR12002:SF116 CLAUDIN CLAUDIN-11-LIKE cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cell-cell junction organization#GO:0045216;cellular component biogenesis#GO:0044085;cell-cell junction assembly#GO:0007043;cell junction organization#GO:0034330;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;cell adhesion#GO:0007155;cellular process#GO:0009987 tight junction#GO:0070160;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cell junction#GO:0030054;bicellular tight junction#GO:0005923;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;apical junction complex#GO:0043296;plasma membrane#GO:0005886 cell junction protein#PC00070;tight junction#PC00214 CIOIN|Ensembl=ENSCING00000019308.1|UniProtKB=F6T518 F6T518 PTHR10426:SF88 STRICTOSIDINE SYNTHASE-RELATED ADIPOCYTE PLASMA MEMBRANE-ASSOCIATED PROTEIN HEMOMUCIN-RELATED hydrolase activity#GO:0016787;catalytic activity#GO:0003824 CIOIN|Ensembl=ENSCING00000006514.3|UniProtKB=F6PVM8 F6PVM8 LOC100175981 PTHR11716:SF101 PHOSPHOLIPASE A2 FAMILY MEMBER BASIC PHOSPHOLIPASE A2 PA-11-LIKE cation binding#GO:0043169;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;phospholipase A2 activity#GO:0004623;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;lipid binding#GO:0008289;phospholipase activity#GO:0004620;ion binding#GO:0043167;phospholipid binding#GO:0005543 lipid metabolic process#GO:0006629;cellular metabolic process#GO:0044237;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;phospholipid metabolic process#GO:0006644;cellular lipid metabolic process#GO:0044255;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 phospholipase#PC00186 CIOIN|Ensembl=ENSCING00000007790.3|UniProtKB=F6X3U5 F6X3U5 PTHR23503:SF8 SOLUTE CARRIER FAMILY 2 FACILITATED GLUCOSE TRANSPORTER PROTEIN 1 transmembrane transporter activity#GO:0022857;sugar transmembrane transporter activity#GO:0051119;transporter activity#GO:0005215;carbohydrate transmembrane transporter activity#GO:0015144 localization#GO:0051179;organic substance transport#GO:0071702;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810;cellular process#GO:0009987;carbohydrate transmembrane transport#GO:0034219;carbohydrate transport#GO:0008643 cellular anatomical entity#GO:0110165;membrane#GO:0016020 secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000007607.3|UniProtKB=F6X5W4 F6X5W4 LOC100186269 PTHR12281:SF31 RP42 RELATED DCN1-LIKE PROTEIN 3 cullin family protein binding#GO:0097602;enzyme binding#GO:0019899;ubiquitin-like protein conjugating enzyme binding#GO:0044390;protein binding#GO:0005515;ubiquitin-like protein binding#GO:0032182;binding#GO:0005488 protein neddylation#GO:0045116;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;transferase complex#GO:1990234 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000012340.2|UniProtKB=F6ZDX4 F6ZDX4 PTHR23084:SF263 PHOSPHATIDYLINOSITOL-4-PHOSPHATE 5-KINASE RELATED MORN REPEAT-CONTAINING PROTEIN 1 transferase#PC00220;kinase#PC00137;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000022202.1|UniProtKB=F6RAN6 F6RAN6 LOC100184403 PTHR12636:SF5 NEP1/MRA1 RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE NEP1 catalytic activity, acting on RNA#GO:0140098;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;transferase activity#GO:0016740;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on a rRNA#GO:0140102;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;rRNA methyltransferase activity#GO:0008649;rRNA binding#GO:0019843;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;RNA methyltransferase activity#GO:0008173 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;RNA modification#GO:0009451;rRNA modification#GO:0000154;RNA processing#GO:0006396;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;ribosome biogenesis#GO:0042254;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;rRNA methylation#GO:0031167;nucleic acid metabolic process#GO:0090304;methylation#GO:0032259;macromolecule methylation#GO:0043414;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;rRNA base methylation#GO:0070475;RNA methylation#GO:0001510 transferase#PC00220;methyltransferase#PC00155;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000009129.3|UniProtKB=F6S3B3 F6S3B3 msxb PTHR24338:SF0 HOMEOBOX PROTEIN MSX MUSCLE SEGMENTATION HOMEOBOX sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;multicellular organism development#GO:0007275;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;embryo development#GO:0009790;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;anatomical structure morphogenesis#GO:0009653;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;embryonic morphogenesis#GO:0048598;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 CIOIN|Ensembl=ENSCING00000014735.2|UniProtKB=F6WVH9 F6WVH9 PTHR10961:SF46 PEROXISOMAL SARCOSINE OXIDASE PEROXISOMAL SARCOSINE OXIDASE oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 oxidase#PC00175;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000001908.3|UniProtKB=F7A2L3 F7A2L3 PTHR10334:SF591 CYSTEINE-RICH SECRETORY PROTEIN-RELATED GLIOMA PATHOGENESIS-RELATED PROTEIN 1-LIKE extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 defense/immunity protein#PC00090 CIOIN|Ensembl=ENSCING00000015277.2|UniProtKB=F6TYB0 F6TYB0 PTHR11276:SF42 DNA POLYMERASE TYPE-X FAMILY MEMBER DNA POLYMERASE BETA DNA-directed DNA polymerase activity#GO:0003887;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on DNA#GO:0140097;DNA polymerase activity#GO:0034061 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;base-excision repair#GO:0006284;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;double-strand break repair via nonhomologous end joining#GO:0006303;nucleic acid metabolic process#GO:0090304;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;response to stress#GO:0006950;nitrogen compound metabolic process#GO:0006807;cellular response to stress#GO:0033554;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-directed DNA polymerase#PC00018 CIOIN|Ensembl=ENSCING00000008390.3|UniProtKB=F6YEH2 F6YEH2 LOC100181998 PTHR12103:SF12 5'-NUCLEOTIDASE DOMAIN-CONTAINING FI20020P1 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;5'-nucleotidase activity#GO:0008253;catalytic activity#GO:0003824;nucleotidase activity#GO:0008252;phosphoric ester hydrolase activity#GO:0042578 nucleotide phosphatase#PC00173;phosphatase#PC00181;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000009308.3|UniProtKB=F6ZN89 F6ZN89 PTHR45766:SF6 DNA ANNEALING HELICASE AND ENDONUCLEASE ZRANB3 FAMILY MEMBER SWI_SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY A-LIKE PROTEIN 1 DNA metabolism protein#PC00009 Wnt signaling pathway#P00057>SWI/SNF#P01435 CIOIN|Ensembl=ENSCING00000004003.3|UniProtKB=F6VXS0 F6VXS0 LOC100186035 PTHR13861:SF2 VACUOLAR ATP SYNTHASE SUBUNIT F V-TYPE PROTON ATPASE SUBUNIT F cellular anatomical entity#GO:0110165;membrane#GO:0016020 ATP synthase#PC00002;primary active transporter#PC00068;transporter#PC00227 CIOIN|Ensembl=ENSCING00000003117.3|UniProtKB=F6RD19 F6RD19 PTHR11937:SF47 ACTIN ACTIN-RELATED PROTEIN 6 nucleosome binding#GO:0031491;protein-containing complex binding#GO:0044877;binding#GO:0005488;chromatin binding#GO:0003682 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;ATPase complex#GO:1904949;intracellular organelle lumen#GO:0070013;INO80-type complex#GO:0097346;SWI/SNF superfamily-type complex#GO:0070603;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;histone deacetylase complex#GO:0000118;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;Swr1 complex#GO:0000812;nuclear protein-containing complex#GO:0140513 actin and actin related protein#PC00039;cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 CIOIN|Ensembl=ENSCING00000024270.1|UniProtKB=H2XPT5 H2XPT5 LOC100184069 PTHR12377:SF2 CYTOSOLIC IRON-SULFUR ASSEMBLY COMPONENT 2B-RELATED CYTOSOLIC IRON-SULFUR ASSEMBLY COMPONENT 2A macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;gene expression#GO:0010467;protein maturation#GO:0051604;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;primary metabolic process#GO:0044238 CIOIN|Ensembl=ENSCING00000022952.1|UniProtKB=A0A1W3JPF5 A0A1W3JPF5 LOC100187386 PTHR12290:SF2 CORNICHON-RELATED PHOSPHOPANTOTHENATE--CYSTEINE LIGASE membrane traffic protein#PC00150 Coenzyme A biosynthesis#P02736>Pantothenate cysteine ligase#P02882 CIOIN|Ensembl=ENSCING00000004625.3|UniProtKB=F6Y6M4 F6Y6M4 PTHR44656:SF7 DEHYDROGENASE/REDUCTASE SDR FAMILY MEMBER 12 DEHYDROGENASE_REDUCTASE SDR FAMILY MEMBER 12 dehydrogenase#PC00092;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000024982.1|UniProtKB=H2XYG9 H2XYG9 PTHR12246:SF13 PALMITOYLTRANSFERASE ZDHHC16 PALMITOYLTRANSFERASE ZDHHC16 protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000020876.1|UniProtKB=H2XK52 H2XK52 LOC100187253 PTHR23506:SF26 GH10249P MFS-TYPE TRANSPORTER SLC18B1 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000005533.3|UniProtKB=F6Y3K6 F6Y3K6 PTHR10783:SF103 XENOTROPIC AND POLYTROPIC RETROVIRUS RECEPTOR 1-RELATED SOLUTE CARRIER FAMILY 53 MEMBER 1 inorganic molecular entity transmembrane transporter activity#GO:0015318;transmembrane transporter activity#GO:0022857;small molecule binding#GO:0036094;binding#GO:0005488;anion binding#GO:0043168;ion binding#GO:0043167;inorganic anion transmembrane transporter activity#GO:0015103;transporter activity#GO:0005215;alcohol binding#GO:0043178 cellular response to stimulus#GO:0051716;transport#GO:0006810;cell communication#GO:0007154;response to nutrient levels#GO:0031667;response to extracellular stimulus#GO:0009991;cellular process#GO:0009987;localization#GO:0051179;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;phosphate ion transport#GO:0006817;cellular response to starvation#GO:0009267;response to stress#GO:0006950;establishment of localization#GO:0051234;cellular response to nutrient levels#GO:0031669;response to starvation#GO:0042594;cellular response to external stimulus#GO:0071496;cellular response to stress#GO:0033554;inorganic anion transport#GO:0015698;cellular response to extracellular stimulus#GO:0031668 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000002482.3|UniProtKB=F6QK56 F6QK56 LOC100184708 PTHR12234:SF0 FORMIMINOTRANSFERASE-CYCLODEAMINASE FORMIMIDOYLTRANSFERASE-CYCLODEAMINASE CIOIN|Ensembl=ENSCING00000007782.3|UniProtKB=F6X4H6 F6X4H6 PTHR22906:SF43 PROPERDIN PROPERDIN CIOIN|Ensembl=ENSCING00000020687.1|UniProtKB=H2XL18 H2XL18 PTHR24253:SF176 TRANSMEMBRANE PROTEASE SERINE CORIN, ISOFORM B serine protease#PC00203;protease#PC00190 CIOIN|Ensembl=ENSCING00000022221.1|UniProtKB=H2XLA0 H2XLA0 PTHR43620:SF7 GLYCEROPHOSPHORYL DIESTER PHOSPHODIESTERASE GLYCEROPHOSPHODIESTER PHOSPHODIESTERASE GDPD5-RELATED hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphoric diester hydrolase activity#GO:0008081;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 phosphodiesterase#PC00185;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000004025.3|UniProtKB=F6SK29 F6SK29 LOC100179473 PTHR19868:SF0 RECEPTOR FOR ACTIVATED PROTEIN KINASE C RACK1 SMALL RIBOSOMAL SUBUNIT PROTEIN RACK1 binding#GO:0005488;ribonucleoprotein complex binding#GO:0043021;ribosome binding#GO:0043022;protein binding#GO:0005515;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;protein-containing complex binding#GO:0044877;kinase binding#GO:0019900 positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;peptide metabolic process#GO:0006518;positive regulation of cellular metabolic process#GO:0031325;gene expression#GO:0010467;biosynthetic process#GO:0009058;positive regulation of protein modification process#GO:0031401;translation#GO:0006412;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;cellular component disassembly#GO:0022411;positive regulation of metabolic process#GO:0009893;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;positive regulation of biological process#GO:0048518;amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;positive regulation of protein phosphorylation#GO:0001934;positive regulation of phosphorylation#GO:0042327;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;positive regulation of phosphorus metabolic process#GO:0010562;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular component organization#GO:0016043;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;organelle disassembly#GO:1903008;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;amide biosynthetic process#GO:0043604;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;positive regulation of protein metabolic process#GO:0051247;peptide biosynthetic process#GO:0043043;positive regulation of phosphate metabolic process#GO:0045937;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;translational elongation#GO:0006414;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000018139.1|UniProtKB=H2XJH6 H2XJH6 PTHR22961:SF16 SER/THR PROTEIN KINASE-TRB SERINE_THREONINE-PROTEIN KINASE 40 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000015215.2|UniProtKB=F6QXQ1 F6QXQ1 LOC100185199 PTHR11959:SF1 4-HYDROXYPHENYLPYRUVATE DIOXYGENASE 4-HYDROXYPHENYLPYRUVATE DIOXYGENASE oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;dioxygenase activity#GO:0051213 cellular aromatic compound metabolic process#GO:0006725;oxoacid metabolic process#GO:0043436;tyrosine metabolic process#GO:0006570;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;aromatic compound catabolic process#GO:0019439;aromatic amino acid metabolic process#GO:0009072;organic cyclic compound metabolic process#GO:1901360;small molecule catabolic process#GO:0044282;nitrogen compound metabolic process#GO:0006807;alpha-amino acid metabolic process#GO:1901605;organic cyclic compound catabolic process#GO:1901361;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;carboxylic acid metabolic process#GO:0019752;aromatic amino acid family catabolic process#GO:0009074;amino acid metabolic process#GO:0006520;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 oxygenase#PC00177;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000007516.3|UniProtKB=F6UJI9 F6UJI9 PTHR23339:SF27 TYROSINE SPECIFIC PROTEIN PHOSPHATASE AND DUAL SPECIFICITY PROTEIN PHOSPHATASE PROTEIN-TYROSINE-PHOSPHATASE hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;protein tyrosine phosphatase activity#GO:0004725;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 regulation of mitotic cell cycle phase transition#GO:1901990;microtubule cytoskeleton organization#GO:0000226;regulation of cell cycle phase transition#GO:1901987;positive regulation of cell cycle#GO:0045787;cellular component organization#GO:0016043;regulation of cell division#GO:0051302;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;regulation of cell cycle process#GO:0010564;regulation of biological process#GO:0050789;positive regulation of cell division#GO:0051781;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;positive regulation of cell cycle process#GO:0090068;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;regulation of cell cycle#GO:0051726;regulation of cytokinesis#GO:0032465;regulation of mitotic cell cycle#GO:0007346;positive regulation of biological process#GO:0048518 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 protein phosphatase#PC00195;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000012778.2|UniProtKB=Q1RPZ3 Q1RPZ3 Ci-ArfGAP-9 PTHR46021:SF2 ARF-GAP WITH DUAL PH DOMAIN-CONTAINING PROTEIN 1-LIKE PROTEIN ARF-GAP WITH DUAL PH DOMAIN-CONTAINING PROTEIN 1 nucleoside-triphosphatase regulator activity#GO:0060589;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;small molecule binding#GO:0036094;binding#GO:0005488;molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047;lipid binding#GO:0008289;anion binding#GO:0043168;phosphatidylinositol binding#GO:0035091;ion binding#GO:0043167;phospholipid binding#GO:0005543;phosphatidylinositol phosphate binding#GO:1901981;enzyme regulator activity#GO:0030234 biological regulation#GO:0065007;regulation of hydrolase activity#GO:0051336;regulation of catalytic activity#GO:0050790;regulation of GTPase activity#GO:0043087;regulation of molecular function#GO:0065009 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 CIOIN|Ensembl=ENSCING00000015330.2|UniProtKB=F7APE7 F7APE7 LOC100187314 PTHR24342:SF12 SERINE/THREONINE-PROTEIN KINASE 17 DEATH-ASSOCIATED PROTEIN KINASE RELATED transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 positive regulation of apoptotic process#GO:0043065;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of apoptotic process#GO:0042981;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;positive regulation of programmed cell death#GO:0043068;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;intracellular signal transduction#GO:0035556;signaling#GO:0023052;positive regulation of biological process#GO:0048518;regulation of programmed cell death#GO:0043067 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000008014.3|UniProtKB=F6SSM8 F6SSM8 PTHR19431:SF0 60S RIBOSOMAL PROTEIN L4 LARGE RIBOSOMAL SUBUNIT PROTEIN UL4 structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;structural molecule activity#GO:0005198;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic large ribosomal subunit#GO:0022625;large ribosomal subunit#GO:0015934;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;ribosomal subunit#GO:0044391 ribosomal protein#PC00202;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000012421.3|UniProtKB=F6Y5C7 F6Y5C7 PTHR11056:SF0 HOMOGENTISATE 1,2-DIOXYGENASE HOMOGENTISATE 1,2-DIOXYGENASE oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;dioxygenase activity#GO:0051213 cellular aromatic compound metabolic process#GO:0006725;oxoacid metabolic process#GO:0043436;proteinogenic amino acid metabolic process#GO:0170039;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;amino acid catabolic process#GO:0009063;organic acid catabolic process#GO:0016054;aromatic compound catabolic process#GO:0019439;aromatic amino acid metabolic process#GO:0009072;organic cyclic compound metabolic process#GO:1901360;small molecule catabolic process#GO:0044282;nitrogen compound metabolic process#GO:0006807;organic cyclic compound catabolic process#GO:1901361;alpha-amino acid metabolic process#GO:1901605;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;carboxylic acid metabolic process#GO:0019752;L-amino acid metabolic process#GO:0170033;aromatic amino acid family catabolic process#GO:0009074;amino acid metabolic process#GO:0006520;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 oxygenase#PC00177;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000023907.1|UniProtKB=H2XJY5 H2XJY5 PTHR14421:SF3 SPERMATOGENESIS-ASSOCIATED PROTEIN 1 SPERMATOGENESIS-ASSOCIATED PROTEIN 1 CIOIN|Ensembl=ENSCING00000007932.3|UniProtKB=F6PH58 F6PH58 PTHR18902:SF25 NUCLEAR MITOTIC APPARATUS PROTEIN 1-RELATED GRIP AND COILED-COIL DOMAIN-CONTAINING PROTEIN 2 cytoskeletal protein#PC00085;microtubule or microtubule-binding cytoskeletal protein#PC00157 CIOIN|Ensembl=ENSCING00000006635.3|UniProtKB=F6U182 F6U182 PTHR22599:SF1 MPS ONE BINDER KINASE ACTIVATOR-LIKE MOB MOB-LIKE PROTEIN PHOCEIN cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 kinase modulator#PC00140;kinase activator#PC00138 CIOIN|Ensembl=ENSCING00000008448.3|UniProtKB=F6UEG1 F6UEG1 PTHR11814:SF55 SULFATE TRANSPORTER SODIUM-INDEPENDENT SULFATE ANION TRANSPORTER cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 transporter#PC00227 CIOIN|Ensembl=ENSCING00000004770.3|UniProtKB=F6PM63 F6PM63 LOC100176424 PTHR11671:SF1 V-TYPE ATP SYNTHASE SUBUNIT D V-TYPE PROTON ATPASE SUBUNIT D ATPase complex#GO:1904949;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;cellular anatomical entity#GO:0110165;membrane#GO:0016020;proton-transporting two-sector ATPase complex#GO:0016469;catalytic complex#GO:1902494 ATP synthase#PC00002;primary active transporter#PC00068;transporter#PC00227 CIOIN|Ensembl=ENSCING00000014594.2|UniProtKB=F6SYE0 F6SYE0 PTHR24419:SF34 INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASE PROTEIN TUBE-RELATED histone modifying activity#GO:0140993;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;mitotic cell cycle#GO:0000278;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell cycle#GO:0007049;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;signaling#GO:0023052 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 Toll pathway-drosophila#P06217>PLL#P06338 CIOIN|Ensembl=ENSCING00000006198.3|UniProtKB=L7N0S6 L7N0S6 PTHR10806:SF6 SIGNAL PEPTIDASE COMPLEX CATALYTIC SUBUNIT SEC11 SIGNAL PEPTIDASE COMPLEX CATALYTIC SUBUNIT SEC11 serine protease#PC00203;protein modifying enzyme#PC00260 Endothelin signaling pathway#P00019>signal peptidase#P00573;Vasopressin synthesis#P04395>Signal Peptidase#P04589 CIOIN|Ensembl=ENSCING00000022057.1|UniProtKB=H2XYP5 H2XYP5 PTHR45973:SF9 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT SDS22-RELATED LEUCINE-RICH REPEAT-CONTAINING PROTEIN 46 phosphatase modulator#PC00184 CIOIN|Ensembl=ENSCING00000022191.1|UniProtKB=F6RFS0 F6RFS0 LOC104266020 PTHR10218:SF212 GTP-BINDING PROTEIN ALPHA SUBUNIT G PROTEIN ALPHA S SUBUNIT GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;ribonucleoside triphosphate phosphatase activity#GO:0017111;G protein-coupled receptor binding#GO:0001664;signaling receptor binding#GO:0005102 response to organic substance#GO:0010033;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;response to organic cyclic compound#GO:0014070;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cellular response to endogenous stimulus#GO:0071495;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;cellular response to organic substance#GO:0071310;response to organonitrogen compound#GO:0010243;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to nitrogen compound#GO:1901699;response to nitrogen compound#GO:1901698;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;response to chemical#GO:0042221;dopamine receptor signaling pathway#GO:0007212;cellular response to organonitrogen compound#GO:0071417;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cellular response to organic cyclic compound#GO:0071407;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052 cytoplasm#GO:0005737;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;cytoplasmic side of plasma membrane#GO:0009898;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622;extrinsic component of membrane#GO:0019898 heterotrimeric G-protein#PC00117;G-protein#PC00020 5HT4 type receptor mediated signaling pathway#P04376>G-protein#P04430;Endothelin signaling pathway#P00019>Gs#P00584;Enkephalin release#P05913>G-Protein (s)#P05977;Histamine H2 receptor mediated signaling pathway#P04386>G-Protein#P04490;Beta3 adrenergic receptor signaling pathway#P04379>G-Protein#P04448;Beta1 adrenergic receptor signaling pathway#P04377>G-Protein#P04436;Beta2 adrenergic receptor signaling pathway#P04378>G-Protein#P04443;Cortocotropin releasing factor receptor signaling pathway#P04380>G-Protein#P04458 CIOIN|Ensembl=ENSCING00000000976.3|UniProtKB=F7ARQ8 F7ARQ8 LOC100184215 PTHR45710:SF26 C-TYPE LECTIN DOMAIN-CONTAINING PROTEIN 180 RH26557P defense/immunity protein#PC00090 CIOIN|Ensembl=ENSCING00000005156.3|UniProtKB=F6SKV4 F6SKV4 LOC100184140 PTHR12013:SF0 SIGNAL RECOGNITION PARTICLE 14 KD PROTEIN SIGNAL RECOGNITION PARTICLE 14 KDA PROTEIN localization#GO:0051179;cellular localization#GO:0051641;protein localization to endoplasmic reticulum#GO:0070972;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;protein targeting#GO:0006605;establishment of protein localization to organelle#GO:0072594;protein targeting to ER#GO:0045047;protein localization to organelle#GO:0033365;cellular process#GO:0009987;establishment of protein localization to endoplasmic reticulum#GO:0072599;establishment of protein localization#GO:0045184;protein localization#GO:0008104 cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000002185.3|UniProtKB=F6SS00 F6SS00 PTHR22847:SF637 WD40 REPEAT PROTEIN WD REPEAT DOMAIN 5B CIOIN|Ensembl=ENSCING00000016005.2|UniProtKB=F6WGN7 F6WGN7 LOC100180537 PTHR10625:SF23 HISTONE DEACETYLASE HDAC1-RELATED HISTONE DEACETYLASE 11 histone modifying activity#GO:0140993;histone deacetylase activity#GO:0004407;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;deacetylase activity#GO:0019213;catalytic activity, acting on a protein#GO:0140096 protein-DNA complex organization#GO:0071824;cellular component organization#GO:0016043;cellular process#GO:0009987;epigenetic regulation of gene expression#GO:0040029;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biosynthetic process#GO:0009889;protein-containing complex organization#GO:0043933;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;chromatin remodeling#GO:0006338;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;histone deacetylase complex#GO:0000118;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 CIOIN|Ensembl=ENSCING00000009583.3|UniProtKB=F6SXS1 F6SXS1 PTHR46024:SF1 HISTONE-LYSINE N-METHYLTRANSFERASE EGGLESS HISTONE-LYSINE N-METHYLTRANSFERASE EGGLESS chromatin/chromatin-binding, or -regulatory protein#PC00077;histone modifying enzyme#PC00261 CIOIN|Ensembl=ENSCING00000020407.1|UniProtKB=H2XRN9 H2XRN9 LOC100187163 PTHR24134:SF9 ANKYRIN REPEAT-CONTAINING PROTEIN DDB_G0279043 ANKYRIN REPEAT AND SOCS BOX PROTEIN 8 CIOIN|Ensembl=ENSCING00000021593.1|UniProtKB=H2XWP0 H2XWP0 LOC100182780 PTHR47980:SF19 LD44762P RAS-RELATED PROTEIN RAB-3 GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;cytoskeletal protein binding#GO:0008092;myosin binding#GO:0017022;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;ribonucleoside triphosphate phosphatase activity#GO:0017111 cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;protein secretion#GO:0009306;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;establishment of protein localization to extracellular region#GO:0035592;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;exocytosis#GO:0006887;establishment of localization#GO:0051234;secretion#GO:0046903;protein transport#GO:0015031;protein localization to extracellular region#GO:0071692;export from cell#GO:0140352;secretion by cell#GO:0032940 presynapse#GO:0098793;synapse#GO:0045202;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;synaptic vesicle#GO:0008021;cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;transport vesicle#GO:0030133;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 CIOIN|Ensembl=ENSCING00000021394.1|UniProtKB=F6SR61 F6SR61 PTHR24412:SF497 KELCH PROTEIN KELCH-LIKE PROTEIN 18 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000008216.3|UniProtKB=F6RU68 F6RU68 PTHR20916:SF26 CYSTEINE AND GLYCINE-RICH PROTEIN 2 BINDING PROTEIN CYSTEINE-RICH PROTEIN 2-BINDING PROTEIN histone modifying activity#GO:0140993;histone acetyltransferase activity#GO:0004402;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;N-acetyltransferase activity#GO:0008080;acyltransferase activity#GO:0016746;acetyltransferase activity#GO:0016407;peptide-lysine-N-acetyltransferase activity#GO:0061733;peptide N-acetyltransferase activity#GO:0034212;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;N-acyltransferase activity#GO:0016410 CIOIN|Ensembl=ENSCING00000003462.3|UniProtKB=F6UB18 F6UB18 LOC100049066 PTHR11473:SF24 AROMATIC AMINO ACID HYDROXYLASE PHENYLALANINE-4-HYDROXYLASE oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000017039.2|UniProtKB=F6U7R3 F6U7R3 LOC100185379 PTHR23399:SF2 DEOXYNUCLEOTIDYLTRANSFERASE TERMINAL-INTERACTING PROTEIN 1 DEOXYNUCLEOTIDYLTRANSFERASE TERMINAL-INTERACTING PROTEIN 1 nucleosome binding#GO:0031491;nucleic acid binding#GO:0003676;protein-containing complex binding#GO:0044877;chromatin binding#GO:0003682;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218 CIOIN|Ensembl=ENSCING00000007505.3|UniProtKB=F6TWU9 F6TWU9 LOC100181512 PTHR43778:SF2 PYRUVATE CARBOXYLASE PYRUVATE CARBOXYLASE, MITOCHONDRIAL ligase activity#GO:0016874;catalytic activity#GO:0003824 oxoacid metabolic process#GO:0043436;monosaccharide metabolic process#GO:0005996;carbohydrate biosynthetic process#GO:0016051;cellular metabolic process#GO:0044237;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;glucose metabolic process#GO:0006006;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;hexose biosynthetic process#GO:0019319;small molecule biosynthetic process#GO:0044283;hexose metabolic process#GO:0019318;carbohydrate metabolic process#GO:0005975;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ligase#PC00142;metabolite interconversion enzyme#PC00262 Pyruvate metabolism#P02772>Pyruvate Carboxylase#P03140 CIOIN|Ensembl=ENSCING00000001160.2|UniProtKB=F6YTU3 F6YTU3 LOC100181500 PTHR11214:SF283 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE N-ACETYLLACTOSAMINIDE BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE 4-LIKE transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;protein O-linked glycosylation#GO:0006493;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 bounding membrane of organelle#GO:0098588;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;Golgi membrane#GO:0000139;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111 CIOIN|Ensembl=ENSCING00000005062.3|UniProtKB=F7A4U1 F7A4U1 PTHR11486:SF160 FIBROBLAST GROWTH FACTOR FIBROBLAST GROWTH FACTOR 22-LIKE ISOFORM X1 molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;binding#GO:0005488;growth factor activity#GO:0008083;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;growth factor receptor binding#GO:0070851;protein binding#GO:0005515;signaling receptor binding#GO:0005102;fibroblast growth factor receptor binding#GO:0005104 positive regulation of gene expression#GO:0010628;regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;positive regulation of cell population proliferation#GO:0008284;positive regulation of protein modification process#GO:0031401;regulation of intracellular signal transduction#GO:1902531;response to fibroblast growth factor#GO:0071774;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;regulation of cell migration#GO:0030334;anatomical structure morphogenesis#GO:0009653;regulation of signal transduction#GO:0009966;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;cellular developmental process#GO:0048869;cellular response to endogenous stimulus#GO:0071495;positive regulation of phosphorus metabolic process#GO:0010562;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;positive regulation of cell communication#GO:0010647;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;fibroblast growth factor receptor signaling pathway#GO:0008543;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;regulation of locomotion#GO:0040012;response to growth factor#GO:0070848;animal organ development#GO:0048513;regulation of signaling#GO:0023051;developmental process#GO:0032502;positive regulation of MAPK cascade#GO:0043410;positive regulation of response to stimulus#GO:0048584;positive regulation of biosynthetic process#GO:0009891;cell differentiation#GO:0030154;response to endogenous stimulus#GO:0009719;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of intracellular signal transduction#GO:1902533;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;signaling#GO:0023052;regulation of cell communication#GO:0010646;positive regulation of protein phosphorylation#GO:0001934;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;regulation of cell population proliferation#GO:0042127;regulation of cell motility#GO:2000145;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;cellular response to growth factor stimulus#GO:0071363;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;animal organ morphogenesis#GO:0009887;cellular response to fibroblast growth factor stimulus#GO:0044344 cytoplasm#GO:0005737;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576;intracellular anatomical structure#GO:0005622 intercellular signal molecule#PC00207;growth factor#PC00112 CIOIN|Ensembl=ENSCING00000021962.1|UniProtKB=H2XVX0 H2XVX0 PTHR45718:SF7 TRANSCRIPTIONAL ACTIVATOR CUBITUS INTERRUPTUS C2H2-TYPE DOMAIN-CONTAINING PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218 CIOIN|Ensembl=ENSCING00000018344.1|UniProtKB=F6PMW1 F6PMW1 PTHR43591:SF101 METHYLTRANSFERASE METHYLTRANSFERASE-LIKE PROTEIN 27 methyltransferase#PC00155;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000013561.2|UniProtKB=F6YBZ8 F6YBZ8 PTHR24329:SF543 HOMEOBOX PROTEIN ARISTALESS FI01017P-RELATED sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 CIOIN|Ensembl=ENSCING00000019571.1|UniProtKB=H2XZ07 H2XZ07 LOC100177065 PTHR28398:SF1 SYNAPTONEMAL COMPLEX CENTRAL ELEMENT PROTEIN 2 SYNAPTONEMAL COMPLEX CENTRAL ELEMENT PROTEIN 2 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;condensed chromosome#GO:0000793;intracellular organelle lumen#GO:0070013;condensed nuclear chromosome#GO:0000794;synaptonemal structure#GO:0099086;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;central element#GO:0000801;synaptonemal complex#GO:0000795 CIOIN|Ensembl=ENSCING00000008111.3|UniProtKB=F6YN13 F6YN13 PTHR11347:SF206 CYCLIC NUCLEOTIDE PHOSPHODIESTERASE HIGH AFFINITY CAMP-SPECIFIC AND IBMX-INSENSITIVE 3',5'-CYCLIC PHOSPHODIESTERASE 8 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;cyclic-nucleotide phosphodiesterase activity#GO:0004112;phosphoric diester hydrolase activity#GO:0008081;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of MAPK cascade#GO:0043408;signal transduction#GO:0007165;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;cell communication#GO:0007154;cellular process#GO:0009987;regulation of intracellular signal transduction#GO:1902531;positive regulation of MAPK cascade#GO:0043410;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of ERK1 and ERK2 cascade#GO:0070372;regulation of signal transduction#GO:0009966;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;positive regulation of intracellular signal transduction#GO:1902533;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;positive regulation of ERK1 and ERK2 cascade#GO:0070374;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;signaling#GO:0023052;cAMP-mediated signaling#GO:0019933;cyclic-nucleotide-mediated signaling#GO:0019935 phosphodiesterase#PC00185 CIOIN|Ensembl=ENSCING00000022200.1|UniProtKB=H2XZK5 H2XZK5 PTHR13382:SF81 MITOCHONDRIAL ATP SYNTHASE COUPLING FACTOR B F-BOX DOMAIN-CONTAINING PROTEIN cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ATP synthase#PC00002;primary active transporter#PC00068;transporter#PC00227 CIOIN|Ensembl=ENSCING00000013919.2|UniProtKB=F6PUR6 F6PUR6 PTHR24300:SF397 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 2U1 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;tetrapyrrole binding#GO:0046906;steroid hydroxylase activity#GO:0008395;oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497;heme binding#GO:0020037 response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;response to chemical#GO:0042221;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 oxygenase#PC00177;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000016431.2|UniProtKB=F7BCF2 F7BCF2 PTHR12112:SF39 BNIP - RELATED EG:152A3.5 PROTEIN (FBGN0003116_PN PROTEIN) hydrolase activity#GO:0016787;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;exopolyphosphatase activity#GO:0004309;catalytic activity#GO:0003824 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 phosphodiesterase#PC00185;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000003472.3|UniProtKB=F6UAN9 F6UAN9 PTHR24044:SF502 NOTCH LIGAND FAMILY MEMBER ANTERIOR PHARYNX IN EXCESS PROTEIN 1-RELATED protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 intercellular signal molecule#PC00207 CIOIN|Ensembl=ENSCING00000000140.3|UniProtKB=F7A0H4 F7A0H4 PTHR43050:SF1 SERINE / THREONINE RACEMASE FAMILY MEMBER SERINE RACEMASE carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;magnesium ion binding#GO:0000287;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;metal ion binding#GO:0046872;isomerase activity#GO:0016853;cation binding#GO:0043169;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;lyase activity#GO:0016829;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167;ATP binding#GO:0005524 organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;alpha-amino acid biosynthetic process#GO:1901607;nitrogen compound metabolic process#GO:0006807;amino acid biosynthetic process#GO:0008652;alpha-amino acid metabolic process#GO:1901605;small molecule biosynthetic process#GO:0044283;carboxylic acid metabolic process#GO:0019752;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 epimerase/racemase#PC00096 Isoleucine biosynthesis#P02748>Threonine dehydratase#P02995 CIOIN|Ensembl=ENSCING00000018550.1|UniProtKB=H2XQX5 H2XQX5 PTHR45765:SF1 METHIONINE--TRNA LIGASE METHIONINE--TRNA LIGASE, CYTOPLASMIC catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;ligase activity#GO:0016874;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;peptide biosynthetic process#GO:0043043;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 aminoacyl-tRNA synthetase#PC00047;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000000736.3|UniProtKB=F6YDS2 F6YDS2 PTHR46223:SF4 HISTONE-LYSINE N-METHYLTRANSFERASE SUV39H HISTONE-LYSINE N-METHYLTRANSFERASE-RELATED N-methyltransferase activity#GO:0008170;histone modifying activity#GO:0140993;transferase activity#GO:0016740;histone methyltransferase activity#GO:0042054;catalytic activity#GO:0003824;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;protein-lysine N-methyltransferase activity#GO:0016279;catalytic activity, acting on a protein#GO:0140096;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;lysine N-methyltransferase activity#GO:0016278;protein methyltransferase activity#GO:0008276 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077;histone modifying enzyme#PC00261 CIOIN|Ensembl=ENSCING00000008704.3|UniProtKB=F6WD96 F6WD96 PTHR10811:SF5 FRINGE-RELATED FRINGE GLYCOSYLTRANSFERASE acetylglucosaminyltransferase activity#GO:0008375;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194;hexosyltransferase activity#GO:0016758 glycosyltransferase#PC00111;metabolite interconversion enzyme#PC00262 Notch signaling pathway#P00045>Fringe#P01107 CIOIN|Ensembl=ENSCING00000006213.3|UniProtKB=F6YWA2 F6YWA2 PTHR45689:SF5 I[[H]] CHANNEL, ISOFORM E I[[H]] CHANNEL, ISOFORM E monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated potassium channel activity#GO:0005249;channel activity#GO:0015267;transporter activity#GO:0005215;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;regulation of membrane potential#GO:0042391;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;localization#GO:0051179;regulation of biological process#GO:0050789;sodium ion transport#GO:0006814;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;regulation of cellular process#GO:0050794;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;regulation of membrane depolarization#GO:0003254;sodium ion transmembrane transport#GO:0035725;potassium ion transport#GO:0006813 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;voltage-gated potassium channel complex#GO:0008076;cation channel complex#GO:0034703;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 CIOIN|Ensembl=ENSCING00000007459.3|UniProtKB=F6YIU9 F6YIU9 PTHR13532:SF3 FAMILY NOT NAMED INTEGRATOR COMPLEX SUBUNIT 14 CIOIN|Ensembl=ENSCING00000005761.3|UniProtKB=F6RSZ1 F6RSZ1 PTHR13322:SF2 C1ORF73 PROTEIN INTEGRATOR COMPLEX SUBUNIT 7 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;snRNA metabolic process#GO:0016073;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;snRNA 3'-end processing#GO:0034472;snRNA processing#GO:0016180;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;integrator complex#GO:0032039 CIOIN|Ensembl=ENSCING00000019314.1|UniProtKB=H2XRN5 H2XRN5 LOC100183424 PTHR11915:SF422 SPECTRIN/FILAMIN RELATED CYTOSKELETAL PROTEIN SPECTRIN ALPHA CHAIN, NON-ERYTHROCYTIC 1-RELATED cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actin filament-based process#GO:0030029;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987;organelle organization#GO:0006996 cortical cytoskeleton#GO:0030863;cell junction#GO:0030054;cellular anatomical entity#GO:0110165;cell cortex#GO:0005938;cell periphery#GO:0071944;cortical actin cytoskeleton#GO:0030864;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cytoskeleton#GO:0005856;cell projection#GO:0042995;plasma membrane#GO:0005886 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 CIOIN|Ensembl=ENSCING00000005460.3|UniProtKB=F6UTN2 F6UTN2 LOC100182711 PTHR11559:SF424 CARBOXYLESTERASE CARBOXYLESTERASE 1D-LIKE ISOFORM X1 esterase#PC00097;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000003563.3|UniProtKB=F6YSX7 F6YSX7 PTHR11800:SF13 DNA-DIRECTED RNA POLYMERASE DNA-DIRECTED RNA POLYMERASES I AND III SUBUNIT RPAC1 catalytic activity, acting on RNA#GO:0140098;5'-3' RNA polymerase activity#GO:0034062;transferase activity#GO:0016740;DNA-directed 5'-3' RNA polymerase activity#GO:0003899;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;RNA polymerase activity#GO:0097747;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring phosphorus-containing groups#GO:0016772;RNA polymerase III activity#GO:0001056;RNA polymerase I activity#GO:0001054 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;DNA-directed RNA polymerase complex#GO:0000428;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular protein-containing complex#GO:0140535;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;RNA polymerase complex#GO:0030880;protein-containing complex#GO:0032991;RNA polymerase III complex#GO:0005666;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;RNA polymerase I complex#GO:0005736;nuclear protein-containing complex#GO:0140513 RNA metabolism protein#PC00031;DNA-directed RNA polymerase#PC00019 CIOIN|Ensembl=ENSCING00000007392.3|UniProtKB=F6ULA8 F6ULA8 LOC100185721 PTHR20883:SF48 PHYTANOYL-COA DIOXYGENASE DOMAIN CONTAINING 1 ECTOINE DIOXYGENASE oxygenase#PC00177;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000004120.3|UniProtKB=F6XUF7 F6XUF7 otp PTHR24329:SF543 HOMEOBOX PROTEIN ARISTALESS FI01017P-RELATED sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 CIOIN|Ensembl=ENSCING00000002334.3|UniProtKB=F6PNN6 F6PNN6 LOC100182083 PTHR22802:SF379 C-TYPE LECTIN SUPERFAMILY MEMBER CHONDROITIN SULFATE PROTEOGLYCAN 2 ISOFORM X1 membrane traffic protein#PC00150 CIOIN|Ensembl=ENSCING00000022790.1|UniProtKB=H2XNZ2 H2XNZ2 PTHR44942:SF4 METHYLTRANSF_11 DOMAIN-CONTAINING PROTEIN METHYLTRANSFERASE TYPE 11 DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000006719.3|UniProtKB=F7A7P7 F7A7P7 PTHR21490:SF0 ENKURIN-RELATED ENKURIN protein binding#GO:0005515;calmodulin binding#GO:0005516;binding#GO:0005488 CIOIN|Ensembl=ENSCING00000002320.3|UniProtKB=F6PN41 F6PN41 LOC100176278 PTHR10286:SF3 INORGANIC PYROPHOSPHATASE INORGANIC PYROPHOSPHATASE hydrolase activity#GO:0016787;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824 cellular metabolic process#GO:0044237;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;metabolic process#GO:0008152 pyrophosphatase#PC00196 CIOIN|Ensembl=ENSCING00000022765.1|UniProtKB=F7AXE7 F7AXE7 LOC100184644 PTHR21637:SF0 BTB/POZ DOMAIN-CONTAINING PROTEIN 10-RELATED AT10158P regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;positive regulation of phosphorylation#GO:0042327;regulation of phosphate metabolic process#GO:0019220;positive regulation of metabolic process#GO:0009893;positive regulation of phosphate metabolic process#GO:0045937;regulation of cellular process#GO:0050794;positive regulation of cellular metabolic process#GO:0031325;biological regulation#GO:0065007;positive regulation of phosphorus metabolic process#GO:0010562;regulation of phosphorylation#GO:0042325;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000004699.3|UniProtKB=F6QNG1 F6QNG1 PTHR28457:SF3 COILED-COIL DOMAIN-CONTAINING PROTEIN 189 CILIARY-ASSOCIATED CALCIUM-BINDING COILED-COIL PROTEIN 1 CIOIN|Ensembl=ENSCING00000005463.3|UniProtKB=F6UTP0 F6UTP0 PTHR11689:SF136 CHLORIDE CHANNEL PROTEIN CLC FAMILY MEMBER H(+)_CL(-) EXCHANGE TRANSPORTER 7 inorganic molecular entity transmembrane transporter activity#GO:0015318;transmembrane transporter activity#GO:0022857;chloride transmembrane transporter activity#GO:0015108;monoatomic anion transmembrane transporter activity#GO:0008509;inorganic anion transmembrane transporter activity#GO:0015103;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ion channel#PC00133;transporter#PC00227 CIOIN|Ensembl=ENSCING00000006509.3|UniProtKB=F6PW34 F6PW34 LOC100183839 PTHR44006:SF1 U5 SMALL NUCLEAR RIBONUCLEOPROTEIN 40 KDA PROTEIN U5 SMALL NUCLEAR RIBONUCLEOPROTEIN 40 KDA PROTEIN nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 ribonucleoprotein complex#GO:1990904;catalytic step 2 spliceosome#GO:0071013;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622 mRNA splicing#P00058>U5#P01474 CIOIN|Ensembl=ENSCING00000001501.3|UniProtKB=L7N0Q6 L7N0Q6 LOC104265699 PTHR13132:SF29 ALPHA- 1,6 -FUCOSYLTRANSFERASE ALPHA-(1,6)-FUCOSYLTRANSFERASE transferase activity#GO:0016740;fucosyltransferase activity#GO:0008417;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein glycosylation#GO:0006486;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein N-linked glycosylation#GO:0006487;protein metabolic process#GO:0019538;glycosylation#GO:0070085;glycoprotein metabolic process#GO:0009100;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 glycosyltransferase#PC00111 Notch signaling pathway#P00045>Neurotic#P01115 CIOIN|Ensembl=ENSCING00000012906.2|UniProtKB=F6PSZ6 F6PSZ6 PTHR12274:SF3 GRANULIN PROGRANULIN cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 CIOIN|Ensembl=ENSCING00000017337.2|UniProtKB=F6XPS9 F6XPS9 LOC100183847 PTHR11241:SF0 DEOXYURIDINE 5'-TRIPHOSPHATE NUCLEOTIDOHYDROLASE DEOXYURIDINE 5'-TRIPHOSPHATE NUCLEOTIDOHYDROLASE cation binding#GO:0043169;pyrophosphatase activity#GO:0016462;magnesium ion binding#GO:0000287;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;metal ion binding#GO:0046872;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ion binding#GO:0043167 cellular aromatic compound metabolic process#GO:0006725;nucleoside triphosphate metabolic process#GO:0009141;pyrimidine nucleotide metabolic process#GO:0006220;carbohydrate derivative metabolic process#GO:1901135;heterocycle catabolic process#GO:0046700;organophosphate biosynthetic process#GO:0090407;pyrimidine-containing compound metabolic process#GO:0072527;organonitrogen compound catabolic process#GO:1901565;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;cellular nitrogen compound catabolic process#GO:0044270;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;nucleoside monophosphate metabolic process#GO:0009123;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;nucleoside phosphate catabolic process#GO:1901292;carbohydrate derivative catabolic process#GO:1901136;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;nucleoside triphosphate catabolic process#GO:0009143;cellular metabolic process#GO:0044237;nucleotide catabolic process#GO:0009166;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;organophosphate catabolic process#GO:0046434;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound catabolic process#GO:0019439;organic cyclic compound catabolic process#GO:1901361;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;small molecule metabolic process#GO:0044281;nucleobase-containing small molecule metabolic process#GO:0055086 metabolite interconversion enzyme#PC00262;phosphatase#PC00181 De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>dUTP pyrophosphatase#P02918 CIOIN|Ensembl=ENSCING00000006732.3|UniProtKB=F6YL86 F6YL86 LOC100178631 PTHR43710:SF2 2-HYDROXYACYL-COA LYASE 2-HYDROXYACYL-COA LYASE 1 cation binding#GO:0043169;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159 oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;lipid oxidation#GO:0034440;cellular metabolic process#GO:0044237;lipid catabolic process#GO:0016042;lipid modification#GO:0030258;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;fatty acid catabolic process#GO:0009062;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;fatty acid metabolic process#GO:0006631;small molecule catabolic process#GO:0044282;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;cellular lipid metabolic process#GO:0044255;cellular lipid catabolic process#GO:0044242;carboxylic acid metabolic process#GO:0019752;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;monocarboxylic acid catabolic process#GO:0072329 lyase#PC00144 CIOIN|Ensembl=ENSCING00000007017.3|UniProtKB=F7AED7 F7AED7 PTHR11689:SF158 CHLORIDE CHANNEL PROTEIN CLC FAMILY MEMBER H(+)_CL(-) EXCHANGE TRANSPORTER 6 inorganic molecular entity transmembrane transporter activity#GO:0015318;transmembrane transporter activity#GO:0022857;chloride transmembrane transporter activity#GO:0015108;monoatomic anion transmembrane transporter activity#GO:0008509;inorganic anion transmembrane transporter activity#GO:0015103;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ion channel#PC00133;transporter#PC00227 CIOIN|Ensembl=ENSCING00000004363|UniProtKB=Q5QQ55 Q5QQ55 xt PTHR46025:SF3 XYLOSYLTRANSFERASE OXT XYLOSYLTRANSFERASE OXT transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000021958.1|UniProtKB=H2XYY9 H2XYY9 LOC100178228 PTHR44755:SF11 NATRIURETIC PEPTIDE RECEPTOR 3-RELATED ATRIAL NATRIURETIC PEPTIDE RECEPTOR 3 ISOFORM X1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;peptide hormone binding#GO:0017046;hormone binding#GO:0042562;binding#GO:0005488;peptide binding#GO:0042277;amide binding#GO:0033218 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 transmembrane signal receptor#PC00197 CIOIN|Ensembl=ENSCING00000012473.2|UniProtKB=F6UTG5 F6UTG5 LOC100186367 PTHR10969:SF33 MICROTUBULE-ASSOCIATED PROTEINS 1A/1B LIGHT CHAIN 3-RELATED GABA(A) RECEPTOR-ASSOCIATED PROTEIN B binding#GO:0005488;ubiquitin-like protein ligase binding#GO:0044389;enzyme binding#GO:0019899;protein binding#GO:0005515;lipid binding#GO:0008289;ubiquitin protein ligase binding#GO:0031625;phospholipid binding#GO:0005543;signaling receptor binding#GO:0005102;GABA receptor binding#GO:0050811 cellular component biogenesis#GO:0044085;macroautophagy#GO:0016236;autophagy of mitochondrion#GO:0000422;response to extracellular stimulus#GO:0009991;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;cellular component disassembly#GO:0022411;cellular response to starvation#GO:0009267;catabolic process#GO:0009056;mitochondrion organization#GO:0007005;autophagosome maturation#GO:0097352;cellular response to extracellular stimulus#GO:0031668;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;cellular component assembly#GO:0022607;cellular response to stimulus#GO:0051716;protein-containing complex disassembly#GO:0032984;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cell communication#GO:0007154;response to nutrient levels#GO:0031667;cellular process#GO:0009987;organelle disassembly#GO:1903008;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;response to stress#GO:0006950;cellular response to nutrient levels#GO:0031669;protein-containing complex organization#GO:0043933;organelle organization#GO:0006996;response to starvation#GO:0042594;cellular response to external stimulus#GO:0071496;autophagosome assembly#GO:0000045;cellular response to stress#GO:0033554;autophagy#GO:0006914 bounding membrane of organelle#GO:0098588;cytoplasm#GO:0005737;autophagosome membrane#GO:0000421;intracellular membrane-bounded organelle#GO:0043231;vacuolar membrane#GO:0005774;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;autophagosome#GO:0005776;intracellular anatomical structure#GO:0005622 non-motor microtubule binding protein#PC00166 CIOIN|Ensembl=ENSCING00000012479.2|UniProtKB=F6W0L1 F6W0L1 PTHR43716:SF1 D-2-HYDROXYGLUTARATE DEHYDROGENASE, MITOCHONDRIAL D-2-HYDROXYGLUTARATE DEHYDROGENASE, MITOCHONDRIAL dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000024200.1|UniProtKB=H2XZH5 H2XZH5 PTHR28080:SF1 PEROXISOMAL BIOGENESIS FACTOR 3 PEROXISOMAL BIOGENESIS FACTOR 3 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 localization within membrane#GO:0051668;cellular localization#GO:0051641;macromolecule localization#GO:0033036;protein localization to membrane#GO:0072657;transport#GO:0006810;nitrogen compound transport#GO:0071705;establishment of protein localization to organelle#GO:0072594;cellular component organization#GO:0016043;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of protein localization to membrane#GO:0090150;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;organelle organization#GO:0006996;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;protein localization to organelle#GO:0033365;peroxisome organization#GO:0007031 bounding membrane of organelle#GO:0098588;peroxisomal membrane#GO:0005778;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;peroxisome#GO:0005777;microbody#GO:0042579;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000003807.3|UniProtKB=F6YH77 F6YH77 PTHR10869:SF244 PROLYL 4-HYDROXYLASE ALPHA SUBUNIT PROLYL 4-HYDROXYLASE SUBUNIT ALPHA-2 2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;dioxygenase activity#GO:0051213 oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular modified amino acid metabolic process#GO:0006575;protein hydroxylation#GO:0018126;alpha-amino acid metabolic process#GO:1901605;protein metabolic process#GO:0019538;carboxylic acid metabolic process#GO:0019752;L-amino acid metabolic process#GO:0170033;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000013882.2|UniProtKB=F6QFM3 F6QFM3 LOC100183327 PTHR21433:SF0 TRANSMEMBRANE PROTEIN INDUCED BY TUMOR NECROSIS FACTOR ALPHA TRANSMEMBRANE PROTEIN 120 HOMOLOG cellular anatomical entity#GO:0110165;membrane#GO:0016020 CIOIN|Ensembl=ENSCING00000018667.1|UniProtKB=H2XNG5 H2XNG5 LOC100181283 PTHR21113:SF4 AGAP001705-PA CHITIN-BINDING TYPE-4 DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000008938.3|UniProtKB=F6Q9P1 F6Q9P1 LOC100177393 PTHR12595:SF0 POS9-ACTIVATING FACTOR FAP7-RELATED ADENYLATE KINASE ISOENZYME 6 chromatin/chromatin-binding, or -regulatory protein#PC00077 CIOIN|Ensembl=ENSCING00000013221.1|UniProtKB=F6V542 F6V542 PTHR10300:SF14 CALCIPRESSIN PROTEIN SARAH phosphatase regulator activity#GO:0019208;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;protein phosphatase regulator activity#GO:0019888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;calcium-mediated signaling#GO:0019722;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;cellular process#GO:0009987;signaling#GO:0023052 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 intercellular signal molecule#PC00207 CIOIN|Ensembl=ENSCING00000005635.3|UniProtKB=H2XTC5 H2XTC5 PTHR12268:SF13 E3 UBIQUITIN-PROTEIN LIGASE KCMF1 E3 UBIQUITIN-PROTEIN LIGASE KCMF1 biological regulation#GO:0065007;synaptic signaling#GO:0099536;regulation of biological process#GO:0050789;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052;cell-cell signaling#GO:0007267 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000002472.3|UniProtKB=F7B480 F7B480 LOC100185737 PTHR12945:SF0 TRANSLATION INITIATION FACTOR EIF3-RELATED TRNA (ADENINE(58)-N(1))-METHYLTRANSFERASE NON-CATALYTIC SUBUNIT TRM6 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;membrane-bounded organelle#GO:0043227;methyltransferase complex#GO:0034708;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 translation initiation factor#PC00224;translation factor#PC00223;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000003333.3|UniProtKB=F6S271 F6S271 LOC100185315 PTHR24064:SF683 SOLUTE CARRIER FAMILY 22 MEMBER CATION_CARNITINE TRANSPORTER, PUTATIVE-RELATED secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000007457.3|UniProtKB=F6YIU2 F6YIU2 PTHR13923:SF11 SEC31-RELATED PROTEIN SECRETORY 31, ISOFORM D endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;endoplasmic reticulum organization#GO:0007029;membrane organization#GO:0061024;transport#GO:0006810;endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;COPII-coated vesicle budding#GO:0090114;establishment of localization in cell#GO:0051649;vesicle organization#GO:0016050;intracellular transport#GO:0046907 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;ER to Golgi transport vesicle membrane#GO:0012507;endoplasmic reticulum exit site#GO:0070971;COPII-coated ER to Golgi transport vesicle#GO:0030134;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;coated vesicle#GO:0030135;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;vesicle coat#GO:0030120;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;transport vesicle membrane#GO:0030658;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;membrane coat#GO:0030117;coated vesicle membrane#GO:0030662;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;transport vesicle#GO:0030133;coated membrane#GO:0048475;cytoplasmic vesicle membrane#GO:0030659;endoplasmic reticulum#GO:0005783 vesicle coat protein#PC00235 CIOIN|Ensembl=ENSCING00000019198.1|UniProtKB=H2XZW2 H2XZW2 PTHR11038:SF16 MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM10 MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM10 cellular localization#GO:0051641;protein insertion into mitochondrial inner membrane#GO:0045039;macromolecule localization#GO:0033036;membrane organization#GO:0061024;transport#GO:0006810;nitrogen compound transport#GO:0071705;establishment of protein localization#GO:0045184;organic substance transport#GO:0071702;establishment of protein localization to membrane#GO:0090150;establishment of localization#GO:0051234;protein targeting to mitochondrion#GO:0006626;mitochondrion organization#GO:0007005;protein localization to organelle#GO:0033365;localization within membrane#GO:0051668;protein localization to membrane#GO:0072657;protein targeting#GO:0006605;establishment of protein localization to organelle#GO:0072594;cellular component organization#GO:0016043;cellular process#GO:0009987;protein localization to mitochondrion#GO:0070585;protein localization#GO:0008104;inner mitochondrial membrane organization#GO:0007007;mitochondrial transport#GO:0006839;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;organelle organization#GO:0006996;establishment of protein localization to mitochondrion#GO:0072655;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;mitochondrial membrane organization#GO:0007006 envelope#GO:0031975;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;organelle membrane#GO:0031090;organelle inner membrane#GO:0019866;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227 transporter#PC00227 CIOIN|Ensembl=ENSCING00000007127.3|UniProtKB=F6S9I2 F6S9I2 LOC100186802 PTHR46014:SF1 TETRATRICOPEPTIDE REPEAT PROTEIN 1 TETRATRICOPEPTIDE REPEAT PROTEIN 1 CIOIN|Ensembl=ENSCING00000001621.3|UniProtKB=F6RYV9 F6RYV9 PTHR45829:SF4 MITOCHONDRIAL CARRIER PROTEIN RIM2 MITOCHONDRIAL CARRIER PROTEIN RIM2 nucleobase-containing compound transmembrane transporter activity#GO:0015932;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 mitochondrial genome maintenance#GO:0000002;organophosphate ester transport#GO:0015748;transmembrane transport#GO:0055085;transport#GO:0006810;nitrogen compound transport#GO:0071705;cellular component organization#GO:0016043;cellular process#GO:0009987;mitochondrial transport#GO:0006839;localization#GO:0051179;organic substance transport#GO:0071702;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;organelle organization#GO:0006996;nucleobase-containing compound transport#GO:0015931;mitochondrion organization#GO:0007005;mitochondrial transmembrane transport#GO:1990542 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 mitochondrial carrier protein#PC00158;secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000009520.3|UniProtKB=F6WWW9 F6WWW9 PTHR13045:SF0 5'-NUCLEOTIDASE 7-METHYLGUANOSINE PHOSPHATE-SPECIFIC 5'-NUCLEOTIDASE hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;5'-nucleotidase activity#GO:0008253;catalytic activity#GO:0003824;nucleotidase activity#GO:0008252;phosphoric ester hydrolase activity#GO:0042578 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 esterase#PC00097 CIOIN|Ensembl=ENSCING00000015865.2|UniProtKB=F6ZIX6 F6ZIX6 LOC100181209 PTHR43675:SF8 ARSENITE METHYLTRANSFERASE ARSENITE METHYLTRANSFERASE methyltransferase activity#GO:0008168;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824 methyltransferase#PC00155;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000001143.3|UniProtKB=F6YV05 F6YV05 LOC100177156 PTHR11920:SF494 GUANYLYL CYCLASE ATRIAL NATRIURETIC PEPTIDE RECEPTOR 2 adenylate cyclase activity#GO:0004016;signaling receptor activity#GO:0038023;cyclase activity#GO:0009975;phosphorus-oxygen lyase activity#GO:0016849;catalytic activity#GO:0003824;lyase activity#GO:0016829;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653 cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;signal transduction#GO:0007165;cyclic nucleotide metabolic process#GO:0009187;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;signaling#GO:0023052;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cell communication#GO:0007154;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;response to stimulus#GO:0050896;ribonucleotide biosynthetic process#GO:0009260;enzyme-linked receptor protein signaling pathway#GO:0007167;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;cGMP biosynthetic process#GO:0006182;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 guanylate cyclase#PC00114 Gonadotropin-releasing hormone receptor pathway#P06664>Npr2#P06796;Endothelin signaling pathway#P00019>Guanylate cyclase#P00581 CIOIN|Ensembl=ENSCING00000001276.3|UniProtKB=F6ZVR2 F6ZVR2 LOC100175803 PTHR12001:SF69 GERANYLGERANYL PYROPHOSPHATE SYNTHASE ALL TRANS-POLYPRENYL-DIPHOSPHATE SYNTHASE PDSS1 prenyltransferase activity#GO:0004659;transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;cellular lipid metabolic process#GO:0044255;isoprenoid metabolic process#GO:0006720;metabolic process#GO:0008152;isoprenoid biosynthetic process#GO:0008299;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704 metabolite interconversion enzyme#PC00262 Cholesterol biosynthesis#P00014>Dimethylallyl trans-transferase#P00490 CIOIN|Ensembl=ENSCING00000017490.2|UniProtKB=F6T1T3 F6T1T3 PTHR21252:SF2 TB1 PROTEIN-RELATED MITOCHONDRIAL OUTER MEMBRANE PROTEIN SLC25A46 cellular component organization or biogenesis#GO:0071840;organelle fission#GO:0048285;mitochondrion organization#GO:0007005;cellular component organization#GO:0016043;cellular process#GO:0009987;organelle organization#GO:0006996;mitochondrial fission#GO:0000266 envelope#GO:0031975;bounding membrane of organelle#GO:0098588;mitochondrial membrane#GO:0031966;intracellular membrane-bounded organelle#GO:0043231;mitochondrial outer membrane#GO:0005741;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867 CIOIN|Ensembl=ENSCING00000018629.1|UniProtKB=H2XQG7 H2XQG7 PTHR43048:SF3 METHYLMALONYL-COA EPIMERASE METHYLMALONYL-COA EPIMERASE, MITOCHONDRIAL isomerase activity#GO:0016853;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;acyl-CoA metabolic process#GO:0006637;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;phosphate-containing compound metabolic process#GO:0006796;primary metabolic process#GO:0044238;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;amide metabolic process#GO:0043603;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 epimerase/racemase#PC00096 Methylmalonyl pathway#P02755>Methylmalonyl-CoA epimerase#P03032 CIOIN|Ensembl=ENSCING00000007006.3|UniProtKB=F7BIC8 F7BIC8 LOC100180479 PTHR23291:SF127 BAX INHIBITOR-RELATED PROTEIN LIFEGUARD 1-LIKE regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;regulation of apoptotic process#GO:0042981;negative regulation of apoptotic signaling pathway#GO:2001234;negative regulation of response to stimulus#GO:0048585;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;regulation of apoptotic signaling pathway#GO:2001233;negative regulation of apoptotic process#GO:0043066;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;negative regulation of programmed cell death#GO:0043069;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648;regulation of programmed cell death#GO:0043067 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ion channel#PC00133;transporter#PC00227 CIOIN|Ensembl=ENSCING00000007364.3|UniProtKB=F6VCT2 F6VCT2 PTHR21597:SF0 THO2 PROTEIN THO COMPLEX SUBUNIT 2 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 mRNA export from nucleus#GO:0006406;cellular localization#GO:0051641;macromolecule biosynthetic process#GO:0009059;macromolecule localization#GO:0033036;establishment of RNA localization#GO:0051236;macromolecule metabolic process#GO:0043170;transport#GO:0006810;nucleic acid transport#GO:0050657;nitrogen compound transport#GO:0071705;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;mRNA transport#GO:0051028;RNA localization#GO:0006403;localization#GO:0051179;organic substance transport#GO:0071702;nuclear export#GO:0051168;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;RNA transport#GO:0050658;nucleobase-containing compound transport#GO:0015931;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;nuclear transport#GO:0051169;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;THO complex#GO:0000347;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;transcription export complex#GO:0000346;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transcription cofactor#PC00217 CIOIN|Ensembl=ENSCING00000015801.2|UniProtKB=H2Y0R5 H2Y0R5 PTHR14336:SF8 TANDEM PH DOMAIN CONTAINING PROTEIN PROTEIN OPY1 CIOIN|Ensembl=ENSCING00000023774.1|UniProtKB=H2XYM0 H2XYM0 LOC100176209 PTHR22146:SF8 CAT EYE SYNDROME CRITICAL REGION PROTEIN 6 PROTEIN FAM166B CIOIN|Ensembl=ENSCING00000020587.1|UniProtKB=H2XM94 H2XM94 LOC100182592 PTHR15186:SF5 RE48077P BNIP3, ISOFORM A cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;apoptotic mitochondrial changes#GO:0008637;membrane organization#GO:0061024;transport#GO:0006810;programmed cell death#GO:0012501;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;regulation of biological process#GO:0050789;mitochondrial transport#GO:0006839;cellular component organization or biogenesis#GO:0071840;apoptotic signaling pathway#GO:0097190;response to stimulus#GO:0050896;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;apoptotic process#GO:0006915;biological regulation#GO:0065007;cell death#GO:0008219;mitochondrial membrane organization#GO:0007006;mitochondrion organization#GO:0007005;signaling#GO:0023052;regulation of programmed cell death#GO:0043067 envelope#GO:0031975;bounding membrane of organelle#GO:0098588;mitochondrial membrane#GO:0031966;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;mitochondrial outer membrane#GO:0005741;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867 CIOIN|Ensembl=ENSCING00000024119.1|UniProtKB=H2XLZ5 H2XLZ5 zf(c2h2_swim)-1 PTHR33936:SF24 PROTEIN CBG17840 C2H2-TYPE DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000003699.3|UniProtKB=F6XIJ2 F6XIJ2 PTHR24241:SF59 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR ADIPOKINETIC HORMONE RECEPTOR, ISOFORM C signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;binding#GO:0005488;peptide binding#GO:0042277;transmembrane signaling receptor activity#GO:0004888;amide binding#GO:0033218 response to organic substance#GO:0010033;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to endogenous stimulus#GO:0009719;cellular response to hormone stimulus#GO:0032870;response to hormone#GO:0009725;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GsPCR#P00720;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GqPCR#P00730 CIOIN|Ensembl=ENSCING00000022137.1|UniProtKB=Q1RLI5 Q1RLI5 Ci-ZF(C2H2)-42 PTHR23235:SF60 KRUEPPEL-LIKE TRANSCRIPTION FACTOR STRIPE, ISOFORM D sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 CIOIN|Ensembl=ENSCING00000004992.3|UniProtKB=F6WLK6 F6WLK6 LOC100185083 PTHR11242:SF0 ARYL HYDROCARBON RECEPTOR INTERACTING PROTEIN RELATED TPR_REGION DOMAIN-CONTAINING PROTEIN chaperone#PC00072 CIOIN|Ensembl=ENSCING00000007930.3|UniProtKB=F6ZS22 F6ZS22 PTHR11785:SF512 AMINO ACID TRANSPORTER SOBREMESA, ISOFORM B L-amino acid transmembrane transporter activity#GO:0015179;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;amino acid transmembrane transporter activity#GO:0015171;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215;organic acid transmembrane transporter activity#GO:0005342 localization#GO:0051179;organic substance transport#GO:0071702;amino acid transmembrane transport#GO:0003333;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;amino acid transport#GO:0006865;organic anion transport#GO:0015711;organic acid transport#GO:0015849;transport#GO:0006810;nitrogen compound transport#GO:0071705;organic acid transmembrane transport#GO:1903825;carboxylic acid transport#GO:0046942;cellular process#GO:0009987;carboxylic acid transmembrane transport#GO:1905039 transporter#PC00227 CIOIN|Ensembl=ENSCING00000011292.2|UniProtKB=F6Y8H0 F6Y8H0 LOC100180921 PTHR15364:SF0 2'-DEOXYNUCLEOSIDE 5'-PHOSPHATE N-HYDROLASE 1 2'-DEOXYNUCLEOSIDE 5'-PHOSPHATE N-HYDROLASE 1 hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;nucleoside phosphate catabolic process#GO:1901292;heterocycle catabolic process#GO:0046700;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate catabolic process#GO:0046434;phosphate-containing compound metabolic process#GO:0006796;cellular nitrogen compound catabolic process#GO:0044270;nucleoside monophosphate metabolic process#GO:0009123;aromatic compound catabolic process#GO:0019439;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;organic cyclic compound catabolic process#GO:1901361;catabolic process#GO:0009056;organophosphate metabolic process#GO:0019637;organic substance catabolic process#GO:1901575;nucleobase-containing compound catabolic process#GO:0034655;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248;nucleobase-containing small molecule metabolic process#GO:0055086 hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000002996.3|UniProtKB=F6QXU2 F6QXU2 PTHR24412:SF272 KELCH PROTEIN KELCH-LIKE PROTEIN DIABLO scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000007740.3|UniProtKB=F6Z015 F6Z015 LOC100179479 PTHR11771:SF153 LIPOXYGENASE LIPOXYGENASE DOMAIN-CONTAINING PROTEIN oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;dioxygenase activity#GO:0051213 lipid metabolic process#GO:0006629;lipid oxidation#GO:0034440;cellular metabolic process#GO:0044237;lipid modification#GO:0030258;cellular lipid metabolic process#GO:0044255;cellular process#GO:0009987;metabolic process#GO:0008152;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704 oxygenase#PC00177;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000001122.3|UniProtKB=F6ZDC7 F6ZDC7 PTHR22573:SF2 PHOSPHOHEXOMUTASE FAMILY MEMBER PHOSPHOGLUCOMUTASE isomerase activity#GO:0016853;intramolecular transferase activity#GO:0016866;catalytic activity#GO:0003824 carbohydrate metabolic process#GO:0005975;organic substance metabolic process#GO:0071704;primary metabolic process#GO:0044238;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 mutase#PC00160 CIOIN|Ensembl=ENSCING00000009742.3|UniProtKB=A0A1W3JP67 A0A1W3JP67 LOC100184245 PTHR24543:SF327 MULTICOPPER OXIDASE-RELATED EGF-LIKE REPEAT AND DISCOIDIN I-LIKE DOMAIN-CONTAINING PROTEIN 3 oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000002946.3|UniProtKB=F6R8U2 F6R8U2 PTHR10157:SF23 DOPAMINE BETA HYDROXYLASE RELATED MOXD1 HOMOLOG 1 hydroxylase#PC00122 CIOIN|Ensembl=ENSCING00000007580.3|UniProtKB=F7A435 F7A435 PTHR22115:SF4 C3ORF6 PROTEIN-RELATED COILED-COIL DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000006270.3|UniProtKB=F6V299 F6V299 PTHR48012:SF16 STERILE20-LIKE KINASE, ISOFORM B-RELATED NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;phosphorylation#GO:0016310;protein phosphorylation#GO:0006468;cellular process#GO:0009987;protein metabolic process#GO:0019538;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000013549.2|UniProtKB=F6YCF6 F6YCF6 PTHR11849:SF190 ETS ETS-DOMAIN PROTEIN transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 CIOIN|Ensembl=ENSCING00000011576.2|UniProtKB=F6SPG6 F6SPG6 PTHR24241:SF196 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR QRFP-LIKE PEPTIDE RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;binding#GO:0005488;peptide binding#GO:0042277;transmembrane signaling receptor activity#GO:0004888;amide binding#GO:0033218 response to organic substance#GO:0010033;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to endogenous stimulus#GO:0009719;cellular response to hormone stimulus#GO:0032870;response to hormone#GO:0009725;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 CIOIN|Ensembl=ENSCING00000024011.1|UniProtKB=H2XV14 H2XV14 LOC100181945 PTHR19282:SF452 TETRASPANIN LD03691P scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000003235.3|UniProtKB=F6ZP18 F6ZP18 PTHR10887:SF5 DNA2/NAM7 HELICASE FAMILY RNA HELICASE AQUARIUS nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 ribonucleoprotein complex#GO:1990904;catalytic step 2 spliceosome#GO:0071013;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622 RNA helicase#PC00032 CIOIN|Ensembl=ENSCING00000018796.1|UniProtKB=H2XW20 H2XW20 LOC101242233 PTHR46780:SF9 PROTEIN EVA-1 D-GALACTOSIDE_L-RHAMNOSE BINDING SUEL LECTIN PROTEIN CIOIN|Ensembl=ENSCING00000023393.1|UniProtKB=H2XVI2 H2XVI2 LOC100179084 PTHR10174:SF225 ALPHA-TOCOPHEROL TRANSFER PROTEIN-RELATED ALPHA-TOCOPHEROL TRANSFER PROTEIN phosphatidylinositol bisphosphate binding#GO:1902936;lipid binding#GO:0008289;phosphatidylinositol binding#GO:0035091;phospholipid binding#GO:0005543;phosphatidylinositol phosphate binding#GO:1901981;binding#GO:0005488 cellular anatomical entity#GO:0110165;membrane#GO:0016020 transfer/carrier protein#PC00219 CIOIN|Ensembl=ENSCING00000003911.3|UniProtKB=F6SN12 F6SN12 LOC100183672 PTHR33560:SF1 PROTEIN FAM227B PROTEIN FAM227A CIOIN|Ensembl=ENSCING00000008902.3|UniProtKB=F6QBJ1 F6QBJ1 PTHR11937:SF526 ACTIN ACTIN, CYTOPLASMIC 1-RELATED intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 actin and actin related protein#PC00039;cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 Integrin signalling pathway#P00034>Actin#P00944;Alzheimer disease-presenilin pathway#P00004>actin#P00114;Nicotinic acetylcholine receptor signaling pathway#P00044>Actin#P01090;Huntington disease#P00029>Actin#P00807;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>F-actin#P00858;Cadherin signaling pathway#P00012>F-actin#P00470;Cytoskeletal regulation by Rho GTPase#P00016>Actin#P00512 CIOIN|Ensembl=ENSCING00000012102.2|UniProtKB=F6X6P0 F6X6P0 PTHR46513:SF41 VITELLOGENIN RECEPTOR-LIKE PROTEIN-RELATED-RELATED LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN transmembrane signal receptor#PC00197 Wnt signaling pathway#P00057>LRP5/6#P01431 CIOIN|Ensembl=ENSCING00000020313.1|UniProtKB=H2XLN9 H2XLN9 PTHR21964:SF13 BREAST CANCER METASTASIS-SUPPRESSOR 1 BRMS1 TRANSCRIPTIONAL REPRESSOR CIOIN|Ensembl=ENSCING00000008098.4|UniProtKB=F6YNG6 F6YNG6 LOC100186564 PTHR10738:SF0 PROTEIN ARGININE N-METHYLTRANSFERASE 5 PROTEIN ARGININE N-METHYLTRANSFERASE 5 N-methyltransferase activity#GO:0008170;histone modifying activity#GO:0140993;transferase activity#GO:0016740;catalytic activity#GO:0003824;histone methyltransferase activity#GO:0042054;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a protein#GO:0140096;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;protein methyltransferase activity#GO:0008276 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000018625.1|UniProtKB=H2XVR9 H2XVR9 PTHR36527:SF3 OS01G0282866 PROTEIN OS01G0282866 PROTEIN CIOIN|Ensembl=ENSCING00000004578.3|UniProtKB=D2KZ69 D2KZ69 Ci-GnRHR4 PTHR24241:SF59 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR ADIPOKINETIC HORMONE RECEPTOR, ISOFORM C signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;binding#GO:0005488;peptide binding#GO:0042277;transmembrane signaling receptor activity#GO:0004888;amide binding#GO:0033218 response to organic substance#GO:0010033;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to endogenous stimulus#GO:0009719;cellular response to hormone stimulus#GO:0032870;response to hormone#GO:0009725;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GsPCR#P00720;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GqPCR#P00730 CIOIN|Ensembl=ENSCING00000004465.3|UniProtKB=F6US42 F6US42 PTHR16146:SF46 INTELECTIN INTELECTIN-1A-RELATED CIOIN|Ensembl=ENSCING00000009497.3|UniProtKB=F6Y901 F6Y901 PTHR42707:SF2 ACYL-COA DEHYDROGENASE ACD11 DEHYDROGENASE oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 dehydrogenase#PC00092;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000021678.1|UniProtKB=H2XZI0 H2XZI0 PTHR24304:SF4 CYTOCHROME P450 FAMILY 7 CYTOCHROME P450 steroid hydroxylase activity#GO:0008395;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497 organic acid biosynthetic process#GO:0016053;organic hydroxy compound metabolic process#GO:1901615;oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;monocarboxylic acid biosynthetic process#GO:0072330;cellular metabolic process#GO:0044237;homeostatic process#GO:0042592;cellular biosynthetic process#GO:0044249;organic hydroxy compound biosynthetic process#GO:1901617;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;chemical homeostasis#GO:0048878;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;organic acid metabolic process#GO:0006082;cholesterol homeostasis#GO:0042632;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;steroid metabolic process#GO:0008202;organic cyclic compound metabolic process#GO:1901360;lipid homeostasis#GO:0055088;small molecule biosynthetic process#GO:0044283;carboxylic acid metabolic process#GO:0019752;steroid biosynthetic process#GO:0006694;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 oxygenase#PC00177;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000001471.3|UniProtKB=F6UVY6 F6UVY6 PTHR10219:SF25 GLYCOLIPID TRANSFER PROTEIN-RELATED PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY A MEMBER 8 lipid transfer activity#GO:0120013;small molecule binding#GO:0036094;binding#GO:0005488;amide binding#GO:0033218;phospholipid transporter activity#GO:0005548;lipid binding#GO:0008289;ion binding#GO:0043167;anion binding#GO:0043168;phospholipid binding#GO:0005543;transporter activity#GO:0005215;lipid transporter activity#GO:0005319 amide transport#GO:0042886;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;membrane organization#GO:0061024;transport#GO:0006810;nitrogen compound transport#GO:0071705;cellular component organization#GO:0016043;lipid localization#GO:0010876;intermembrane lipid transfer#GO:0120009;cellular process#GO:0009987;lipid transport#GO:0006869 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;membrane#GO:0016020;intracellular anatomical structure#GO:0005622 transfer/carrier protein#PC00219 CIOIN|Ensembl=ENSCING00000009694.3|UniProtKB=F6U6R8 F6U6R8 LOC100186403 PTHR21223:SF2 CBY1-INTERACTING BAR DOMAIN-CONTAINING PROTEIN HOMOLOG CBY1-INTERACTING BAR DOMAIN-CONTAINING PROTEIN HOMOLOG organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cell projection organization#GO:0030030;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;microtubule cytoskeleton#GO:0015630;ciliary basal body#GO:0036064;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cilium#GO:0005929;intracellular organelle#GO:0043229;ciliary transition zone#GO:0035869;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000005623.3|UniProtKB=F7AT24 F7AT24 PTHR10845:SF192 REGULATOR OF G PROTEIN SIGNALING DOUBLE HIT, ISOFORM B G-protein modulator#PC00022;protein-binding activity modulator#PC00095;GTPase-activating protein#PC00257 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>RGS#P00704;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>RGS#P00731 CIOIN|Ensembl=ENSCING00000005927.3|UniProtKB=F6ZHD7 F6ZHD7 PTHR46362:SF1 GEM-ASSOCIATED PROTEIN 5 GEM-ASSOCIATED PROTEIN 5 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159;mRNA 3'-UTR binding#GO:0003730 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;RNA processing#GO:0006396;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;protein-RNA complex assembly#GO:0022618;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;spliceosomal snRNP assembly#GO:0000387;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;protein-containing complex organization#GO:0043933;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;ribonucleoprotein complex biogenesis#GO:0022613;mRNA processing#GO:0006397;protein-RNA complex organization#GO:0071826;RNA splicing, via transesterification reactions#GO:0000375 SMN-Sm protein complex#GO:0034719;cytoplasm#GO:0005737;SMN complex#GO:0032797;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;Sm-like protein family complex#GO:0120114;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000022382.1|UniProtKB=H2XKF1 H2XKF1 LOC100180313 PTHR13019:SF25 GOLGI APPARATUS MEMBRANE PROTEIN TVP23 GOLGI APPARATUS MEMBRANE PROTEIN TVP23 HOMOLOG cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;protein secretion#GO:0009306;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;establishment of protein localization to extracellular region#GO:0035592;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;secretion#GO:0046903;protein transport#GO:0015031;protein localization to extracellular region#GO:0071692;export from cell#GO:0140352;secretion by cell#GO:0032940 bounding membrane of organelle#GO:0098588;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;Golgi membrane#GO:0000139;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000003679.3|UniProtKB=F6ZUZ5 F6ZUZ5 PTHR45620:SF42 PDF RECEPTOR-LIKE PROTEIN-RELATED G-PROTEIN COUPLED RECEPTOR SEB-2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 CIOIN|Ensembl=ENSCING00000002382.3|UniProtKB=F6R4Q0 F6R4Q0 PTHR12137:SF54 CARBOHYDRATE SULFOTRANSFERASE CARBOHYDRATE SULFOTRANSFERASE sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824 transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000000991.3|UniProtKB=F6YLP6 F6YLP6 PTHR45664:SF12 PROTEIN ZERKNUELLT 1-RELATED PANCREAS_DUODENUM HOMEOBOX PROTEIN 1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 CIOIN|Ensembl=ENSCING00000012642.2|UniProtKB=F6WS42 F6WS42 PTHR13192:SF3 MY011 PROTEIN COBALAMIN TRAFFICKING PROTEIN CBLD CIOIN|Ensembl=ENSCING00000017374.2|UniProtKB=F7B1Z2 F7B1Z2 PTHR48027:SF18 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN 87F-RELATED HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN 87F-RELATED CIOIN|Ensembl=ENSCING00000004292.3|UniProtKB=F6TST6 F6TST6 PTHR46018:SF2 ZINC PHOSPHODIESTERASE ELAC PROTEIN 1 ZINC PHOSPHODIESTERASE ELAC PROTEIN 1 catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a nucleic acid#GO:0140640;endonuclease activity#GO:0004519;RNA nuclease activity#GO:0004540;RNA endonuclease activity#GO:0004521 phosphodiesterase#PC00185;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000016946.2|UniProtKB=F7AK80 F7AK80 PTHR23101:SF104 RAB GDP/GTP EXCHANGE FACTOR PROTEIN SPRINT nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;binding#GO:0005488;molecular function regulator activity#GO:0098772;enzyme binding#GO:0019899;protein binding#GO:0005515;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;guanyl-nucleotide exchange factor activity#GO:0005085 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;endocytic vesicle#GO:0030139;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 CIOIN|Ensembl=ENSCING00000024199.1|UniProtKB=H2XLW7 H2XLW7 LOC100179066 PTHR13389:SF0 PUMILIO HOMOLOG 3 PUMILIO HOMOLOG 3 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 regulation of protein metabolic process#GO:0051246;regulation of amide metabolic process#GO:0034248;regulation of nitrogen compound metabolic process#GO:0051171;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biosynthetic process#GO:0009889;post-transcriptional regulation of gene expression#GO:0010608;biological regulation#GO:0065007;regulation of translation#GO:0006417;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000008160.3|UniProtKB=F6UR25 F6UR25 LOC100177766 PTHR11101:SF80 PHOSPHATE TRANSPORTER PHOSPHATE TRANSPORTER inorganic molecular entity transmembrane transporter activity#GO:0015318;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 localization#GO:0051179;inorganic anion transmembrane transport#GO:0098661;phosphate ion transport#GO:0006817;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;transport#GO:0006810;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;inorganic anion transport#GO:0015698 transporter#PC00227 CIOIN|Ensembl=ENSCING00000018798.1|UniProtKB=H2XX55 H2XX55 PTHR20935:SF0 PHOSPHOGLYCERATE MUTASE-RELATED SERINE_THREONINE-PROTEIN PHOSPHATASE PGAM5, MITOCHONDRIAL mutase#PC00160 CIOIN|Ensembl=ENSCING00000007743.3|UniProtKB=F6Z010 F6Z010 LOC100175495 PTHR10794:SF63 ABHYDROLASE DOMAIN-CONTAINING PROTEIN ALPHA_BETA HYDROLASE 1, ISOFORM A hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;lipase activity#GO:0016298;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular lipid metabolic process#GO:0044255;organic substance metabolic process#GO:0071704;primary metabolic process#GO:0044238;metabolic process#GO:0008152 serine protease#PC00203;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000012209.1|UniProtKB=F7BPH5 F7BPH5 LOC100183675 PTHR10517:SF14 FOLATE RECEPTOR FOLATE RECEPTOR 1-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 membrane trafficking regulatory protein#PC00151 CIOIN|Ensembl=ENSCING00000005575.3|UniProtKB=F6U4M6 F6U4M6 LOC100177703 PTHR11955:SF57 FATTY ACID BINDING PROTEIN FATTY ACID-BINDING PROTEIN, BRAIN fatty acid binding#GO:0005504;small molecule binding#GO:0036094;binding#GO:0005488;carboxylic acid binding#GO:0031406;lipid binding#GO:0008289;ion binding#GO:0043167;organic acid binding#GO:0043177;anion binding#GO:0043168 localization#GO:0051179;monocarboxylic acid transport#GO:0015718;organic substance transport#GO:0071702;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;organic anion transport#GO:0015711;fatty acid transport#GO:0015908;organic acid transport#GO:0015849;transport#GO:0006810;carboxylic acid transport#GO:0046942;lipid localization#GO:0010876;lipid transport#GO:0006869 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transfer/carrier protein#PC00219 CIOIN|Ensembl=ENSCING00000011303.2|UniProtKB=F6XKD5 F6XKD5 PTHR24372:SF77 GLYCOPROTEIN HORMONE RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 response to organic substance#GO:0010033;positive regulation of adenylate cyclase activity#GO:0045762;regulation of lyase activity#GO:0051339;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;cellular response to stimulus#GO:0051716;regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;cellular response to endogenous stimulus#GO:0071495;cellular response to chemical stimulus#GO:0070887;positive regulation of catalytic activity#GO:0043085;cellular response to organic substance#GO:0071310;regulation of cyclase activity#GO:0031279;positive regulation of molecular function#GO:0044093;cell communication#GO:0007154;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;positive regulation of cyclase activity#GO:0031281;hormone-mediated signaling pathway#GO:0009755;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to endogenous stimulus#GO:0009719;response to hormone#GO:0009725;cellular response to hormone stimulus#GO:0032870;response to chemical#GO:0042221;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of lyase activity#GO:0051349;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 CIOIN|Ensembl=ENSCING00000001560.3|UniProtKB=F6XZ31 F6XZ31 PTHR10468:SF0 PROTEIN O-LINKED-MANNOSE BETA-1,2-N-ACETYLGLUCOSAMINYLTRANSFERASE 1/ALPHA-1,3-MANNOSYL-GLYCOPROTEIN 2-BETA-N-ACETYLGLUCOSAMINYLTRANSFERASE ALPHA-1,3-MANNOSYL-GLYCOPROTEIN 2-BETA-N-ACETYLGLUCOSAMINYLTRANSFERASE acetylglucosaminyltransferase activity#GO:0008375;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;UDP-glycosyltransferase activity#GO:0008194 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000018650.1|UniProtKB=H2XMH0 H2XMH0 PTHR31214:SF2 PROTEIN FAM221A-RELATED PROTEIN FAM221A CIOIN|Ensembl=ENSCING00000004096.3|UniProtKB=F6YHL8 F6YHL8 PTHR11136:SF5 FOLYLPOLYGLUTAMATE SYNTHASE-RELATED FOLYLPOLYGLUTAMATE SYNTHASE, MITOCHONDRIAL ligase activity#GO:0016874;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;folic acid-containing compound metabolic process#GO:0006760;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;heterocycle biosynthetic process#GO:0018130;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;cellular modified amino acid metabolic process#GO:0006575;aromatic compound biosynthetic process#GO:0019438;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ligase#PC00142;metabolite interconversion enzyme#PC00262 Formyltetrahydrofolate biosynthesis#P02743>Dihydrofolate synthase#P02958;Tetrahydrofolate biosynthesis#P02742>Dihydrofolate synthase#P02943 CIOIN|Ensembl=ENSCING00000004351.3|UniProtKB=F7BMK8 F7BMK8 PTHR36978:SF4 P-LOOP CONTAINING NUCLEOTIDE TRIPHOSPHATE HYDROLASE P-LOOP CONTAINING NUCLEOSIDE TRIPHOSPHATE HYDROLASE PROTEIN metabolite interconversion enzyme#PC00262;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000005957.3|UniProtKB=F6WFB4 F6WFB4 PTHR10605:SF56 HEPARAN SULFATE SULFOTRANSFERASE BIFUNCTIONAL HEPARAN SULFATE N-DEACETYLASE_N-SULFOTRANSFERASE transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000024796.1|UniProtKB=F6ZI65 F6ZI65 PTHR46190:SF1 SI:CH211-201H21.5-RELATED SI:CH211-201H21.5 CIOIN|Ensembl=ENSCING00000004293.3|UniProtKB=F6TTJ0 F6TTJ0 PTHR21324:SF18 FASTING-INDUCIBLE INTEGRAL MEMBRANE PROTEIN TM6P1-RELATED DNA DAMAGE-REGULATED AUTOPHAGY MODULATOR PROTEIN 1-LIKE scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000003257.3|UniProtKB=F6Z535 F6Z535 PTHR43811:SF19 FKBP-TYPE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKPA 39 KDA FK506-BINDING NUCLEAR PROTEIN peptidyl-prolyl cis-trans isomerase activity#GO:0003755;isomerase activity#GO:0016853;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 chaperone#PC00072 TGF-beta signaling pathway#P00052>FKBP12#P01288 CIOIN|Ensembl=ENSCING00000002429.3|UniProtKB=F6QH26 F6QH26 PTHR10334:SF590 CYSTEINE-RICH SECRETORY PROTEIN-RELATED SCP DOMAIN-CONTAINING PROTEIN extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 defense/immunity protein#PC00090 CIOIN|Ensembl=ENSCING00000007763.3|UniProtKB=F6XTP5 F6XTP5 LOC100180132 PTHR28336:SF3 BA1-643 CHROMOSOME 11 C6ORF62 HOMOLOG CIOIN|Ensembl=ENSCING00000006876.3|UniProtKB=F6ZCR7 F6ZCR7 PTHR12151:SF5 ELECTRON TRANSPORT PROTIN SCO1/SENC FAMILY MEMBER AT19154P cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;respiratory chain complex IV assembly#GO:0008535;mitochondrial respiratory chain complex assembly#GO:0033108;protein-containing complex organization#GO:0043933;organelle organization#GO:0006996;cytochrome complex assembly#GO:0017004;protein-containing complex assembly#GO:0065003;mitochondrial cytochrome c oxidase assembly#GO:0033617;cellular component organization#GO:0016043;mitochondrion organization#GO:0007005;cellular process#GO:0009987 oxidase#PC00175;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000016136.2|UniProtKB=F6VY76 F6VY76 PTHR47977:SF26 RAS-RELATED PROTEIN RAB RAB1B, MEMBER RAS ONCO FAMILY GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;ion binding#GO:0043167;anion binding#GO:0043168 localization#GO:0051179;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization#GO:0051234;transport#GO:0006810 small GTPase#PC00208;G-protein#PC00020 CIOIN|Ensembl=ENSCING00000014778.2|UniProtKB=F6VM90 F6VM90 LOC100181322 PTHR19282:SF551 TETRASPANIN RE08073P-RELATED cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000024815.1|UniProtKB=H2XYE0 H2XYE0 LOC100180579 PTHR10091:SF0 ALDOSE-1-EPIMERASE GALACTOSE MUTAROTASE racemase and epimerase activity, acting on carbohydrates and derivatives#GO:0016857;isomerase activity#GO:0016853;catalytic activity#GO:0003824 monosaccharide metabolic process#GO:0005996;small molecule catabolic process#GO:0044282;carbohydrate catabolic process#GO:0016052;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;hexose metabolic process#GO:0019318;carbohydrate metabolic process#GO:0005975;glucose metabolic process#GO:0006006;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704 epimerase/racemase#PC00096;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000006183.3|UniProtKB=F7BK27 F7BK27 LOC100180627 PTHR21530:SF7 PHEROMONE SHUTDOWN PROTEIN TRAB DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000000352.3|UniProtKB=F6WDK3 F6WDK3 PTHR10865:SF28 METASTASIS-ASSOCIATED PROTEIN AND MESODERM INDUCTION EARLY RESPONSE PROTEIN ELM2 DOMAIN-CONTAINING PROTEIN molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;histone deacetylase binding#GO:0042826;transcription corepressor activity#GO:0003714;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;enzyme binding#GO:0019899;protein binding#GO:0005515 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of biosynthetic process#GO:0009890;negative regulation of RNA metabolic process#GO:0051253;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 CIOIN|Ensembl=ENSCING00000024666.1|UniProtKB=H2XQX2 H2XQX2 PTHR23320:SF158 MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MS4A -RELATED CREB-BINDING PROTEIN-LIKE ISOFORM X1 transporter#PC00227 CIOIN|Ensembl=ENSCING00000002198.3|UniProtKB=F6S4S1 F6S4S1 PTHR24349:SF527 SERINE/THREONINE-PROTEIN KINASE LD17393P transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;protein binding#GO:0005515;calmodulin binding#GO:0005516;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular process#GO:0009987;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000011514.2|UniProtKB=F6WU12 F6WU12 PTHR44085:SF2 SEPIAPTERIN REDUCTASE SEPIAPTERIN REDUCTASE oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 cellular aromatic compound metabolic process#GO:0006725;organic hydroxy compound metabolic process#GO:1901615;heterocycle metabolic process#GO:0046483;alcohol biosynthetic process#GO:0046165;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic hydroxy compound biosynthetic process#GO:1901617;alcohol metabolic process#GO:0006066;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;heterocycle biosynthetic process#GO:0018130;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;aromatic compound biosynthetic process#GO:0019438;small molecule biosynthetic process#GO:0044283;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 reductase#PC00198;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000002197.3|UniProtKB=F6Z7A9 F6Z7A9 LOC100185712 PTHR12883:SF0 ADIPOCYTE-SPECIFIC PROTEIN 4-RELATED PAT COMPLEX SUBUNIT CCDC47 cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000002951.3|UniProtKB=F6R8G4 F6R8G4 LOC100186495 PTHR13906:SF14 PORCUPINE LYSOPHOSPHOLIPID ACYLTRANSFERASE 5 acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;O-acyltransferase activity#GO:0008374 lipid metabolic process#GO:0006629;phospholipid biosynthetic process#GO:0008654;organophosphate biosynthetic process#GO:0090407;glycerolipid biosynthetic process#GO:0045017;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;glycerophospholipid metabolic process#GO:0006650;organic substance biosynthetic process#GO:1901576;lipid modification#GO:0030258;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;phosphatidylcholine biosynthetic process#GO:0006656;glycerolipid metabolic process#GO:0046486;nitrogen compound metabolic process#GO:0006807;glycerophospholipid biosynthetic process#GO:0046474;organophosphate metabolic process#GO:0019637;phosphatidylcholine metabolic process#GO:0046470;cellular lipid metabolic process#GO:0044255;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;membrane#GO:0016020 transferase#PC00220;acetyltransferase#PC00038;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000020518.1|UniProtKB=H2XQ16 H2XQ16 PTHR24240:SF223 OPSIN MELATONIN RECEPTOR 1B signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 signal transduction#GO:0007165;response to light stimulus#GO:0009416;cellular response to stimulus#GO:0051716;detection of stimulus#GO:0051606;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;regulation of cellular process#GO:0050794;response to radiation#GO:0009314;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;response to abiotic stimulus#GO:0009628;signaling#GO:0023052;cellular response to light stimulus#GO:0071482 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 CIOIN|Ensembl=ENSCING00000005542.3|UniProtKB=F6XEW4 F6XEW4 PTHR45847:SF6 FATTY ACID AMIDE HYDROLASE FATTY ACID AMIDE HYDROLASE hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;oxoacid metabolic process#GO:0043436;cellular metabolic process#GO:0044237;lipid catabolic process#GO:0016042;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;fatty acid catabolic process#GO:0009062;primary metabolic process#GO:0044238;fatty acid metabolic process#GO:0006631;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;cellular lipid metabolic process#GO:0044255;carboxylic acid catabolic process#GO:0046395;carboxylic acid metabolic process#GO:0019752;cellular lipid catabolic process#GO:0044242;monocarboxylic acid catabolic process#GO:0072329;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000004703.3|UniProtKB=F6QND3 F6QND3 PTHR13454:SF11 PROTEIN MCM10 HOMOLOG PROTEIN MCM10 HOMOLOG sequence-specific double-stranded DNA binding#GO:1990837;DNA replication origin binding#GO:0003688;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;single-stranded DNA binding#GO:0003697;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;DNA-templated DNA replication#GO:0006261;DNA replication#GO:0006260;DNA replication initiation#GO:0006270;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;chromosome#GO:0005694;nuclear replication fork#GO:0043596;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;replication fork#GO:0005657 CIOIN|Ensembl=ENSCING00000004748.3|UniProtKB=F6PRL5 F6PRL5 PTHR10390:SF44 HOMEOBOX PROTEIN SIX SIX HOMEOBOX 4 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 CIOIN|Ensembl=ENSCING00000008196.3|UniProtKB=F6PK03 F6PK03 LOC100186836 PTHR24369:SF211 ANTIGEN BSP, PUTATIVE-RELATED LEUCINE-RICH REPEAT-CONTAINING PROTEIN 15-LIKE cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 CIOIN|Ensembl=ENSCING00000002213.3|UniProtKB=F6Z743 F6Z743 LOC100175227 PTHR10635:SF0 COATOMER SUBUNIT BETA COATOMER SUBUNIT BETA localization#GO:0051179;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;intra-Golgi vesicle-mediated transport#GO:0006891;establishment of localization#GO:0051234;transport#GO:0006810;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;coated vesicle#GO:0030135;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;vesicle coat#GO:0030120;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;Golgi-associated vesicle membrane#GO:0030660;protein-containing complex#GO:0032991;COPI vesicle coat#GO:0030126;endomembrane system#GO:0012505;membrane coat#GO:0030117;coated vesicle membrane#GO:0030662;COPI-coated vesicle#GO:0030137;Golgi-associated vesicle#GO:0005798;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;coated membrane#GO:0048475;cytoplasmic vesicle membrane#GO:0030659 vesicle coat protein#PC00235 CIOIN|Ensembl=ENSCING00000007561.3|UniProtKB=F6T7Y6 F6T7Y6 LOC100177347 PTHR24068:SF132 UBIQUITIN-CONJUGATING ENZYME E2 NEDD8-CONJUGATING ENZYME UBC12 ubiquitin-like protein conjugating enzyme activity#GO:0061650;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin conjugating enzyme activity#GO:0061631;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein neddylation#GO:0045116;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein polyubiquitination#GO:0000209;post-translational protein modification#GO:0043687;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000002394.3|UniProtKB=F6QI54 F6QI54 PTHR10027:SF33 CALCIUM-ACTIVATED POTASSIUM CHANNEL ALPHA CHAIN CALCIUM-ACTIVATED POTASSIUM CHANNEL SUBUNIT ALPHA-1-RELATED monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;potassium ion transmembrane transporter activity#GO:0015079;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;channel activity#GO:0015267;monoatomic ion-gated channel activity#GO:0022839;calcium-activated potassium channel activity#GO:0015269;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;calcium-activated cation channel activity#GO:0005227;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;ligand-gated monoatomic cation channel activity#GO:0099094;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;ligand-gated channel activity#GO:0022834 localization#GO:0051179;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;potassium ion transmembrane transport#GO:0071805;monoatomic cation transport#GO:0006812;inorganic ion transmembrane transport#GO:0098660;monoatomic ion transport#GO:0006811;cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;potassium ion transport#GO:0006813 cellular anatomical entity#GO:0110165;membrane#GO:0016020 ion channel#PC00133;transporter#PC00227 CIOIN|Ensembl=ENSCING00000019722.1|UniProtKB=H2Y1A1 H2Y1A1 LOC113474017 PTHR14942:SF0 U11/U12 SMALL NUCLEAR RIBONUCLEOPROTEIN 25 KDA PROTEIN U11_U12 SMALL NUCLEAR RIBONUCLEOPROTEIN 25 KDA PROTEIN CIOIN|Ensembl=ENSCING00000012094.2|UniProtKB=A0A1W2WML0 A0A1W2WML0 LOC100182832 PTHR15679:SF8 PCNA-ASSOCIATED FACTOR PCNA-ASSOCIATED FACTOR protein-containing complex binding#GO:0044877;binding#GO:0005488;chromatin binding#GO:0003682 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;postreplication repair#GO:0006301;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;translesion synthesis#GO:0019985;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;nucleobase-containing compound biosynthetic process#GO:0034654;DNA biosynthetic process#GO:0071897;DNA synthesis involved in DNA repair#GO:0000731;aromatic compound biosynthetic process#GO:0019438;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000008882.3|UniProtKB=F6QXH6 F6QXH6 LOC100177752 PTHR11071:SF561 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE D-RELATED peptidyl-prolyl cis-trans isomerase activity#GO:0003755;isomerase activity#GO:0016853;catalytic activity, acting on a protein#GO:0140096;binding#GO:0005488;catalytic activity#GO:0003824;peptide binding#GO:0042277;amide binding#GO:0033218 macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein peptidyl-prolyl isomerization#GO:0000413;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein folding#GO:0006457;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 chaperone#PC00072 CIOIN|Ensembl=ENSCING00000008021.3|UniProtKB=H2XZL7 H2XZL7 LOC100180280 PTHR34441:SF1 MOTILE SPERM DOMAIN-CONTAINING PROTEIN 1 MOTILE SPERM DOMAIN-CONTAINING 1 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000011386.2|UniProtKB=F6TJR3 F6TJR3 PTHR46139:SF3 ALKALINE CERAMIDASE ALKALINE CERAMIDASE lipid metabolic process#GO:0006629;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;lipid catabolic process#GO:0016042;cellular process#GO:0009987;sphingolipid metabolic process#GO:0006665;ceramide metabolic process#GO:0006672;primary metabolic process#GO:0044238;membrane lipid metabolic process#GO:0006643;nitrogen compound metabolic process#GO:0006807;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;cellular lipid metabolic process#GO:0044255;sphingolipid catabolic process#GO:0030149;amide metabolic process#GO:0043603;cellular lipid catabolic process#GO:0044242;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 CIOIN|Ensembl=ENSCING00000024457.1|UniProtKB=H2XZ27 H2XZ27 PTHR23053:SF0 DLEC1 DELETED IN LUNG AND ESOPHAGEAL CANCER 1 HYDROCEPHALUS-INDUCING PROTEIN HOMOLOG cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cell projection organization#GO:0030030;microtubule cytoskeleton organization#GO:0000226;microtubule-based movement#GO:0007018;cellular component organization#GO:0016043;axoneme assembly#GO:0035082;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031;cilium movement#GO:0003341;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;microtubule bundle formation#GO:0001578;cytoskeleton organization#GO:0007010;plasma membrane bounded cell projection assembly#GO:0120031 axoneme#GO:0005930;cytoplasmic region#GO:0099568;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;plasma membrane bounded cell projection cytoplasm#GO:0032838;membrane-bounded organelle#GO:0043227;ciliary plasm#GO:0097014;cytoskeleton#GO:0005856;cell projection#GO:0042995;cilium#GO:0005929 CIOIN|Ensembl=ENSCING00000004419.3|UniProtKB=F6XI54 F6XI54 LOC100178850 PTHR24251:SF30 OVOCHYMASE-RELATED MEMBRANE FRIZZLED-RELATED PROTEIN serine protease#PC00203;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000003693.3|UniProtKB=F6XIM3 F6XIM3 gnrhr2 PTHR24241:SF59 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR ADIPOKINETIC HORMONE RECEPTOR, ISOFORM C signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;binding#GO:0005488;peptide binding#GO:0042277;transmembrane signaling receptor activity#GO:0004888;amide binding#GO:0033218 response to organic substance#GO:0010033;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to endogenous stimulus#GO:0009719;cellular response to hormone stimulus#GO:0032870;response to hormone#GO:0009725;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GsPCR#P00720;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GqPCR#P00730 CIOIN|Ensembl=ENSCING00000006195.3|UniProtKB=F7B1K2 F7B1K2 PTHR14186:SF26 INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN-RELATED KAZAL TYPE SERINE PEPTIDASE INHIBITOR DOMAIN 1 biological regulation#GO:0065007;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;regulation of signaling#GO:0023051 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 CIOIN|Ensembl=ENSCING00000013917.2|UniProtKB=F6PUY5 F6PUY5 PTHR24372:SF77 GLYCOPROTEIN HORMONE RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 response to organic substance#GO:0010033;positive regulation of adenylate cyclase activity#GO:0045762;regulation of lyase activity#GO:0051339;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;cellular response to stimulus#GO:0051716;regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;cellular response to endogenous stimulus#GO:0071495;cellular response to chemical stimulus#GO:0070887;positive regulation of catalytic activity#GO:0043085;cellular response to organic substance#GO:0071310;regulation of cyclase activity#GO:0031279;positive regulation of molecular function#GO:0044093;cell communication#GO:0007154;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;positive regulation of cyclase activity#GO:0031281;hormone-mediated signaling pathway#GO:0009755;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to endogenous stimulus#GO:0009719;response to hormone#GO:0009725;cellular response to hormone stimulus#GO:0032870;response to chemical#GO:0042221;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of lyase activity#GO:0051349;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 CIOIN|Ensembl=ENSCING00000003124.3|UniProtKB=F6RCR9 F6RCR9 LOC100184788 PTHR24343:SF466 SERINE/THREONINE KINASE AMP-ACTIVATED PROTEIN KINASE ALPHA SUBUNIT, ISOFORM A transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;phosphorylation#GO:0016310;protein phosphorylation#GO:0006468;cellular process#GO:0009987;protein metabolic process#GO:0019538;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000004083.3|UniProtKB=F6Z0T1 F6Z0T1 PTHR24356:SF418 SERINE/THREONINE-PROTEIN KINASE SERINE_THREONINE-PROTEIN KINASE WARTS transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular process#GO:0009987;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000008747.3|UniProtKB=F6T0Z3 F6T0Z3 PTHR11984:SF53 CONNEXIN GAP JUNCTION PROTEIN wide pore channel activity#GO:0022829;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;channel activity#GO:0015267 biological regulation#GO:0065007;regulation of biological process#GO:0050789;cell communication#GO:0007154;cellular process#GO:0009987;cell-cell signaling#GO:0007267;signaling#GO:0023052 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 cell junction protein#PC00070;gap junction#PC00105 CIOIN|Ensembl=ENSCING00000018313.1|UniProtKB=H2XMD1 H2XMD1 PTHR10751:SF29 GUANYLATE BINDING PROTEIN ATLASTIN GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;ion binding#GO:0043167;anion binding#GO:0043168 heterotrimeric G-protein#PC00117;G-protein#PC00020 CIOIN|Ensembl=ENSCING00000007779.3|UniProtKB=F6XSK1 F6XSK1 LOC100176892 PTHR28259:SF1 FLUORIDE EXPORT PROTEIN 1-RELATED FLUORIDE EXPORT PROTEIN 1-RELATED inorganic molecular entity transmembrane transporter activity#GO:0015318;transmembrane transporter activity#GO:0022857;monoatomic anion transmembrane transporter activity#GO:0008509;inorganic anion transmembrane transporter activity#GO:0015103;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075 localization#GO:0051179;inorganic anion transmembrane transport#GO:0098661;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic anion transmembrane transport#GO:0098656;monoatomic ion transmembrane transport#GO:0034220;monoatomic anion transport#GO:0006820;transport#GO:0006810;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 CIOIN|Ensembl=ENSCING00000001672.3|UniProtKB=F6XWC8 F6XWC8 PTHR45739:SF1 MATRIX PROTEIN, PUTATIVE-RELATED EXTRACELLULAR MATRIX ORGANIZING PROTEIN FRAS1 anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;developmental process#GO:0032502 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165 CIOIN|Ensembl=ENSCING00000009859.3|UniProtKB=F6XG40 F6XG40 PTHR11220:SF72 HEME-BINDING PROTEIN-RELATED HEME-BINDING PROTEIN 2-LIKE ISOFORM X2 tetrapyrrole binding#GO:0046906;binding#GO:0005488;organic cyclic compound binding#GO:0097159;heme binding#GO:0020037 CIOIN|Ensembl=ENSCING00000002864.3|UniProtKB=F6TMB6 F6TMB6 LOC100184914 PTHR47979:SF33 DRAB11-RELATED DRAB11 GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;anion binding#GO:0043168;ion binding#GO:0043167 localization#GO:0051179;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization#GO:0051234;transport#GO:0006810 cytoplasm#GO:0005737;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular vesicle#GO:0097708;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 small GTPase#PC00208 CIOIN|Ensembl=ENSCING00000003824.3|UniProtKB=F6ZSV0 F6ZSV0 LOC100175536 PTHR24064:SF650 SOLUTE CARRIER FAMILY 22 MEMBER MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000009124.3|UniProtKB=F6TJT5 F6TJT5 PTHR12137:SF54 CARBOHYDRATE SULFOTRANSFERASE CARBOHYDRATE SULFOTRANSFERASE sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824 transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000000630.3|UniProtKB=F6RRD5 F6RRD5 LOC104266474 PTHR12815:SF18 SORTING AND ASSEMBLY MACHINERY SAMM50 PROTEIN FAMILY MEMBER SORTING AND ASSEMBLY MACHINERY COMPONENT 50 HOMOLOG CIOIN|Ensembl=ENSCING00000009510.3|UniProtKB=F6XJ50 F6XJ50 LOC100178472 PTHR45828:SF33 CYTOCHROME B561/FERRIC REDUCTASE TRANSMEMBRANE DOMON DOMAIN-CONTAINING PROTEIN cellular anatomical entity#GO:0110165;membrane#GO:0016020 reductase#PC00198;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000007677.3|UniProtKB=L7N0T5 L7N0T5 LOC100181688 PTHR11588:SF486 TUBULIN TUBULIN ALPHA-4 CHAIN carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;structural molecule activity#GO:0005198;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167;structural constituent of cytoskeleton#GO:0005200 cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;microtubule-based process#GO:0007017;organelle organization#GO:0006996;microtubule cytoskeleton organization#GO:0000226;cytoskeleton organization#GO:0007010;cell cycle#GO:0007049;cellular component organization#GO:0016043;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622 tubulin#PC00228;microtubule or microtubule-binding cytoskeletal protein#PC00157 CIOIN|Ensembl=ENSCING00000013805.2|UniProtKB=F6R9K5 F6R9K5 PTHR24300:SF397 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 2U1 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;tetrapyrrole binding#GO:0046906;steroid hydroxylase activity#GO:0008395;oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497;heme binding#GO:0020037 response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;response to chemical#GO:0042221;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 oxygenase#PC00177;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000009022.3|UniProtKB=F6RBZ6 F6RBZ6 smad6_7 PTHR13703:SF54 SMAD MOTHERS AGAINST DECAPENTAPLEGIC HOMOLOG cis-regulatory region sequence-specific DNA binding#GO:0000987;SMAD binding#GO:0046332;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;molecular function regulator activity#GO:0098772;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;protein binding#GO:0005515;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;molecular function inhibitor activity#GO:0140678 signal transduction#GO:0007165;regulation of nitrogen compound metabolic process#GO:0051171;response to growth factor#GO:0070848;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;cellular response to BMP stimulus#GO:0071773;cell differentiation#GO:0030154;response to endogenous stimulus#GO:0009719;anatomical structure morphogenesis#GO:0009653;regulation of biosynthetic process#GO:0009889;response to BMP#GO:0071772;regulation of macromolecule biosynthetic process#GO:0010556;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;regulation of gene expression#GO:0010468;signaling#GO:0023052;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;cellular response to endogenous stimulus#GO:0071495;regulation of DNA-templated transcription#GO:0006355;BMP signaling pathway#GO:0030509;cell communication#GO:0007154;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;cellular response to growth factor stimulus#GO:0071363;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;cell surface receptor signaling pathway#GO:0007166;anatomical structure development#GO:0048856;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218 TGF-beta signaling pathway#P00052>RSmads#P01292 CIOIN|Ensembl=ENSCING00000013226.2|UniProtKB=F6V4V0 F6V4V0 PTHR12106:SF27 SORTILIN RELATED SORTILIN-RELATED RECEPTOR membrane traffic protein#PC00150 CIOIN|Ensembl=ENSCING00000001223.3|UniProtKB=F6SY55 F6SY55 PTHR46481:SF10 ZINC FINGER BED DOMAIN-CONTAINING PROTEIN 4 ZINC FINGER BED DOMAIN-CONTAINING PROTEIN 39 CIOIN|Ensembl=ENSCING00000006256.3|UniProtKB=F6VPX3 F6VPX3 PTHR23063:SF2 PHOSPHOLIPID ACYLTRANSFERASE GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE 4, ISOFORM D-RELATED acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;O-acyltransferase activity#GO:0008374 lipid metabolic process#GO:0006629;triglyceride metabolic process#GO:0006641;glycerolipid biosynthetic process#GO:0045017;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;acylglycerol metabolic process#GO:0006639;lipid biosynthetic process#GO:0008610;primary metabolic process#GO:0044238;neutral lipid metabolic process#GO:0006638;glycerolipid metabolic process#GO:0046486;triglyceride biosynthetic process#GO:0019432;cellular lipid metabolic process#GO:0044255;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 acyltransferase#PC00042 CIOIN|Ensembl=ENSCING00000006253.3|UniProtKB=F6YBI0 F6YBI0 PTHR22906:SF54 PROPERDIN IG-LIKE DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000024306.1|UniProtKB=H2XWC8 H2XWC8 PTHR19325:SF574 COMPLEMENT COMPONENT-RELATED SUSHI DOMAIN-CONTAINING SUSHI, VON WILLEBRAND FACTOR TYPE A, EGF AND PENTRAXIN DOMAIN-CONTAINING PROTEIN 1 complement component#PC00078 CIOIN|Ensembl=ENSCING00000020988.1|UniProtKB=H2XQL8 H2XQL8 PTHR12419:SF115 OTU DOMAIN CONTAINING PROTEIN PROTEIN OVARIAN TUMOR LOCUS-RELATED cysteine-type peptidase activity#GO:0008234;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;cysteine-type deubiquitinase activity#GO:0004843 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;protein modification by small protein removal#GO:0070646;protein deubiquitination#GO:0016579;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cysteine protease#PC00081;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000024279.1|UniProtKB=F6XMT9 F6XMT9 PTHR24012:SF491 RNA BINDING PROTEIN LD36772P-RELATED nucleic acid binding#GO:0003676;single-stranded RNA binding#GO:0003727;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159;mRNA binding#GO:0003729;poly(A) binding#GO:0008143;mRNA 3'-UTR binding#GO:0003730 cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000001515.3|UniProtKB=F6S855 F6S855 LOC100185129 PTHR43157:SF31 PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN-RELATED PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000021034.1|UniProtKB=H2Y0E6 H2Y0E6 LOC100175646 PTHR45665:SF9 AQUAPORIN-8 AQUAPORIN-8 inorganic molecular entity transmembrane transporter activity#GO:0015318;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;channel activity#GO:0015267;water transmembrane transporter activity#GO:0005372 localization#GO:0051179;water transport#GO:0006833;establishment of localization#GO:0051234;fluid transport#GO:0042044;transport#GO:0006810 cellular anatomical entity#GO:0110165;membrane#GO:0016020 CIOIN|Ensembl=ENSCING00000002602.3|UniProtKB=F7B376 F7B376 LOC100180419 PTHR12704:SF2 TRANS-GOLGI PROTEIN GMX33 GOLGI PHOSPHOPROTEIN 3 HOMOLOG SAURON CIOIN|Ensembl=ENSCING00000008359.3|UniProtKB=F7AK09 F7AK09 PTHR20961:SF148 GLYCOSYLTRANSFERASE EGF DOMAIN-SPECIFIC O-LINKED N-ACETYLGLUCOSAMINE TRANSFERASE transferase activity#GO:0016740;catalytic activity#GO:0003824;glycosyltransferase activity#GO:0016757 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000011742.2|UniProtKB=F6TAV4 F6TAV4 PTHR22996:SF0 MAHOGUNIN RE60872P-RELATED transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000006174.3|UniProtKB=Q1RPU5 Q1RPU5 Ci-ZF(RING)-30 PTHR44080:SF1 E3 UBIQUITIN-PROTEIN LIGASE COP1 E3 UBIQUITIN-PROTEIN LIGASE COP1 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 P53 pathway feedback loops 1#P04392>Cop-1#P04540;P53 pathway feedback loops 1#P04392>Cop-1#G04683 CIOIN|Ensembl=ENSCING00000005645.3|UniProtKB=F6ZQX2 F6ZQX2 PTHR13132:SF29 ALPHA- 1,6 -FUCOSYLTRANSFERASE ALPHA-(1,6)-FUCOSYLTRANSFERASE transferase activity#GO:0016740;fucosyltransferase activity#GO:0008417;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein glycosylation#GO:0006486;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein N-linked glycosylation#GO:0006487;protein metabolic process#GO:0019538;glycosylation#GO:0070085;glycoprotein metabolic process#GO:0009100;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 glycosyltransferase#PC00111 Notch signaling pathway#P00045>Neurotic#P01115 CIOIN|Ensembl=ENSCING00000006481.3|UniProtKB=F6Q2H6 F6Q2H6 PTHR11884:SF1 SELECTIN LIGAND RELATED GOLGI APPARATUS PROTEIN 1 CIOIN|Ensembl=ENSCING00000015656.2|UniProtKB=F6Z1H7 F6Z1H7 LOC100185535 PTHR46384:SF1 MOTILE SPERM DOMAIN-CONTAINING PROTEIN 2 MOTILE SPERM DOMAIN-CONTAINING PROTEIN 2 cellular anatomical entity#GO:0110165;organelle membrane contact site#GO:0044232;organelle#GO:0043226;endomembrane system#GO:0012505 CIOIN|Ensembl=ENSCING00000012879.2|UniProtKB=F6PUL1 F6PUL1 LOC100185472 PTHR24180:SF14 CYCLIN-DEPENDENT KINASE INHIBITOR 2C-RELATED ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 45 kinase inhibitor#PC00139 CIOIN|Ensembl=ENSCING00000007275.3|UniProtKB=F6SVM8 F6SVM8 PTHR11339:SF386 EXTRACELLULAR MATRIX GLYCOPROTEIN RELATED HEMOLECTIN, ISOFORM A external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 extracellular matrix protein#PC00102 CIOIN|Ensembl=ENSCING00000007170.3|UniProtKB=F6ZB45 F6ZB45 LOC100186846 PTHR23195:SF7 YEATS DOMAIN YEATS DOMAIN-CONTAINING PROTEIN 2 protein binding#GO:0005515;histone binding#GO:0042393;binding#GO:0005488 protein-DNA complex organization#GO:0071824;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;cellular component organization#GO:0016043;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;protein-containing complex organization#GO:0043933;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;chromatin remodeling#GO:0006338;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 histone acetyltransferase complex#GO:0000123;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;acetyltransferase complex#GO:1902493;chromatin#GO:0000785;protein-DNA complex#GO:0032993;catalytic complex#GO:1902494;NuA4 histone acetyltransferase complex#GO:0035267;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein acetyltransferase complex#GO:0031248;protein-containing complex#GO:0032991;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227 general transcription factor#PC00259 CIOIN|Ensembl=ENSCING00000023469.1|UniProtKB=H2XKY2 H2XKY2 PTHR11214:SF283 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE N-ACETYLLACTOSAMINIDE BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE 4-LIKE transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;protein O-linked glycosylation#GO:0006493;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 bounding membrane of organelle#GO:0098588;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;Golgi membrane#GO:0000139;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111 CIOIN|Ensembl=ENSCING00000008560.3|UniProtKB=F6X189 F6X189 LOC100181892 PTHR10766:SF41 TRANSMEMBRANE 9 SUPERFAMILY PROTEIN TRANSMEMBRANE 9 SUPERFAMILY MEMBER 3 localization#GO:0051179;localization within membrane#GO:0051668;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;protein localization to membrane#GO:0072657;cellular process#GO:0009987;protein localization#GO:0008104 cellular anatomical entity#GO:0110165;membrane#GO:0016020 transporter#PC00227 CIOIN|Ensembl=ENSCING00000012970.2|UniProtKB=F6RBE5 F6RBE5 PTHR31733:SF1 RIBONUCLEASE KAPPA RIBONUCLEASE KAPPA catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a nucleic acid#GO:0140640;endonuclease activity#GO:0004519;RNA nuclease activity#GO:0004540;RNA endonuclease activity#GO:0004521 endoribonuclease#PC00094;RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000006353.3|UniProtKB=F6PR16 F6PR16 PTHR11153:SF6 SIDEROFLEXIN SIDEROFLEXIN-5 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 localization#GO:0051179;mitochondrial transport#GO:0006839;cellular process#GO:0009987;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;mitochondrial transmembrane transport#GO:1990542;transport#GO:0006810 envelope#GO:0031975;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227 primary active transporter#PC00068;transporter#PC00227 CIOIN|Ensembl=ENSCING00000001152.3|UniProtKB=F6YUM3 F6YUM3 LOC100179992 PTHR13225:SF3 MISEXPRESSION SUPPRESSOR OF RAS 6 UPF0489 PROTEIN C5ORF22 CIOIN|Ensembl=ENSCING00000006085.3|UniProtKB=F6ZFJ9 F6ZFJ9 PTHR45992:SF2 EUKARYOTIC ELONGATION FACTOR 2 KINASE-RELATED EUKARYOTIC ELONGATION FACTOR 2 KINASE transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 response to organic substance#GO:0010033;response to organic cyclic compound#GO:0014070;protein-containing complex disassembly#GO:0032984;response to oxygen-containing compound#GO:1901700;cellular component organization#GO:0016043;cellular process#GO:0009987;response to stimulus#GO:0050896;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;cellular component disassembly#GO:0022411;response to chemical#GO:0042221;protein-containing complex organization#GO:0043933;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036 Oxidative stress response#P00046>eEF2K#P01127;p38 MAPK pathway#P05918>eEF2K#P06022 CIOIN|Ensembl=ENSCING00000023956.1|UniProtKB=H2XWY5 H2XWY5 PTHR24064:SF577 SOLUTE CARRIER FAMILY 22 MEMBER GH09241P secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000014063.2|UniProtKB=F6QNW0 F6QNW0 PTHR11829:SF142 FORKHEAD BOX PROTEIN FORK-HEAD DOMAIN-CONTAINING PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;anatomical structure morphogenesis#GO:0009653;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 CIOIN|Ensembl=ENSCING00000011816.2|UniProtKB=F7A515 F7A515 LOC100178798 PTHR43677:SF3 SHORT-CHAIN DEHYDROGENASE/REDUCTASE PROSTAGLANDIN REDUCTASE 3 oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000012105.2|UniProtKB=F6X6H9 F6X6H9 LOC100187521 PTHR13236:SF0 DYNEIN 2 LIGHT INTERMEDIATE CHAIN, ISOFORM 2 CYTOPLASMIC DYNEIN 2 LIGHT INTERMEDIATE CHAIN 1 protein binding#GO:0005515;binding#GO:0005488 cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;cilium assembly#GO:0060271;cell projection organization#GO:0030030;transport#GO:0006810;microtubule-based movement#GO:0007018;cellular component organization#GO:0016043;intraciliary transport involved in cilium assembly#GO:0035735;intraciliary retrograde transport#GO:0035721;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;transport along microtubule#GO:0010970;cell projection assembly#GO:0030031;intraciliary transport#GO:0042073;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based transport#GO:0099111;microtubule-based process#GO:0007017;establishment of localization#GO:0051234;organelle organization#GO:0006996;cytoskeleton-dependent intracellular transport#GO:0030705;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;protein-containing complex localization#GO:0031503 axoneme#GO:0005930;microtubule organizing center#GO:0005815;catalytic complex#GO:1902494;cytoplasmic region#GO:0099568;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;microtubule associated complex#GO:0005875;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;ciliary basal body#GO:0036064;ciliary plasm#GO:0097014;plasma membrane bounded cell projection cytoplasm#GO:0032838;membrane-bounded organelle#GO:0043227;dynein complex#GO:0030286;cell projection#GO:0042995;cytoskeleton#GO:0005856;cilium#GO:0005929;cytoplasmic dynein complex#GO:0005868 cytoskeletal protein#PC00085;microtubule or microtubule-binding cytoskeletal protein#PC00157 CIOIN|Ensembl=ENSCING00000007882.2|UniProtKB=F6TGJ7 F6TGJ7 PTHR19325:SF571 COMPLEMENT COMPONENT-RELATED SUSHI DOMAIN-CONTAINING SUSHI DOMAIN-CONTAINING PROTEIN complement component#PC00078 CIOIN|Ensembl=ENSCING00000002208.3|UniProtKB=F6ZPZ7 F6ZPZ7 PTHR46584:SF1 HMG DOMAIN-CONTAINING PROTEIN 4 HMG DOMAIN-CONTAINING PROTEIN 4 HMG box transcription factor#PC00024 CIOIN|Ensembl=ENSCING00000002689.3|UniProtKB=F6XPF5 F6XPF5 PTHR22802:SF379 C-TYPE LECTIN SUPERFAMILY MEMBER CHONDROITIN SULFATE PROTEOGLYCAN 2 ISOFORM X1 membrane traffic protein#PC00150 CIOIN|Ensembl=ENSCING00000023561.1|UniProtKB=H2XRJ8 H2XRJ8 PTHR13501:SF8 CHLOROPLAST 50S RIBOSOMAL PROTEIN L22-RELATED LARGE RIBOSOMAL SUBUNIT PROTEIN UL22M structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;large ribosomal subunit#GO:0015934;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000004038.3|UniProtKB=F6RXC5 F6RXC5 PTHR12659:SF7 RHO-TYPE GTPASE ACTIVATING PROTEIN CROSSVEINLESS C, ISOFORM C nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 regulation of cell communication#GO:0010646;regulation of Rho protein signal transduction#GO:0035023;regulation of signaling#GO:0023051;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of intracellular signal transduction#GO:1902531;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036 GTPase-activating protein#PC00257 CIOIN|Ensembl=ENSCING00000009210.4|UniProtKB=F6WN54 F6WN54 PTHR21422:SF9 RAB3 GTPASE-ACTIVATING PROTEIN CATALYTIC SUBUNIT RAB3 GTPASE-ACTIVATING PROTEIN CATALYTIC SUBUNIT nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 regulation of molecular function#GO:0065009;regulation of GTPase activity#GO:0043087;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;biological regulation#GO:0065007;positive regulation of molecular function#GO:0044093;regulation of hydrolase activity#GO:0051336;regulation of catalytic activity#GO:0050790;positive regulation of hydrolase activity#GO:0051345 GTPase-activating protein#PC00257 CIOIN|Ensembl=ENSCING00000014082.2|UniProtKB=F6U0A7 F6U0A7 PTHR14453:SF67 PARP/ZINC FINGER CCCH TYPE DOMAIN CONTAINING PROTEIN POLY [ADP-RIBOSE] POLYMERASE molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714;protein-macromolecule adaptor activity#GO:0030674 negative regulation of gene expression#GO:0010629;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of biosynthetic process#GO:0009890;negative regulation of metabolic process#GO:0009892;regulation of biological process#GO:0050789;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000022534.1|UniProtKB=H2Y1K8 H2Y1K8 PTHR45751:SF11 COPINE FAMILY PROTEIN 1 COPINE FAMILY PROTEIN 2 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 calcium-binding protein#PC00060 CIOIN|Ensembl=ENSCING00000022356.1|UniProtKB=H2XNG1 H2XNG1 PTHR46063:SF1 KELCH DOMAIN-CONTAINING PROTEIN KELCH DOMAIN-CONTAINING PROTEIN 4 CIOIN|Ensembl=ENSCING00000003770.3|UniProtKB=F6TIR0 F6TIR0 PTHR43073:SF2 DIHYDROPYRIMIDINE DEHYDROGENASE [NADP(+)] DIHYDROPYRIMIDINE DEHYDROGENASE [NADP(+)] dehydrogenase#PC00092;oxidoreductase#PC00176 Pyrimidine Metabolism#P02771>Dihydrouracil Dehydrogenase#P03128 CIOIN|Ensembl=ENSCING00000021679.1|UniProtKB=H2XQ91 H2XQ91 PTHR19855:SF12 WD40 REPEAT PROTEIN 12, 37 WD REPEAT-CONTAINING PROTEIN 37 CIOIN|Ensembl=ENSCING00000006447.3|UniProtKB=F6UFU8 F6UFU8 PTHR13891:SF1 CYTOCHROME C OXIDASE ASSEMBLY FACTOR 7 CYTOCHROME C OXIDASE ASSEMBLY FACTOR 7 CIOIN|Ensembl=ENSCING00000007893.3|UniProtKB=F6STW3 F6STW3 PTHR22774:SF11 CHOREIN N-TERMINAL DOMAIN-CONTAINING PROTEIN CHOREIN N-TERMINAL DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000014149.2|UniProtKB=F7ARK5 F7ARK5 LOC100185828 PTHR36978:SF4 P-LOOP CONTAINING NUCLEOTIDE TRIPHOSPHATE HYDROLASE P-LOOP CONTAINING NUCLEOSIDE TRIPHOSPHATE HYDROLASE PROTEIN metabolite interconversion enzyme#PC00262;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000023723.1|UniProtKB=H2XQI0 H2XQI0 PTHR10887:SF322 DNA2/NAM7 HELICASE FAMILY HELICASE MOV-10 negative regulation of gene expression#GO:0010629;regulatory ncRNA-mediated gene silencing#GO:0031047;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of biosynthetic process#GO:0009890;negative regulation of metabolic process#GO:0009892;regulation of biological process#GO:0050789;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulatory ncRNA-mediated post-transcriptional gene silencing#GO:0035194;regulation of cellular process#GO:0050794;regulation of biosynthetic process#GO:0009889;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;P granule#GO:0043186;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464;intracellular anatomical structure#GO:0005622 RNA helicase#PC00032 CIOIN|Ensembl=ENSCING00000002423.3|UniProtKB=F6SWZ3 F6SWZ3 bf-3 PTHR46393:SF7 SUSHI DOMAIN-CONTAINING PROTEIN COMPLEMENT C2 CIOIN|Ensembl=ENSCING00000003152.3|UniProtKB=F6QJH8 F6QJH8 PTHR22426:SF2 ARGININE_SERINE-RICH COILED-COIL PROTEIN 2 ARGININE_SERINE-RICH COILED-COIL PROTEIN 2 CIOIN|Ensembl=ENSCING00000008360.3|UniProtKB=F7AK04 F7AK04 PTHR14269:SF4 CDP-DIACYLGLYCEROL--GLYCEROL-3-PHOSPHATE 3-PHOSPHATIDYLTRANSFERASE-RELATED CAT EYE SYNDROME CRITICAL REGION PROTEIN 5 lipid metabolic process#GO:0006629;phospholipid biosynthetic process#GO:0008654;organophosphate biosynthetic process#GO:0090407;glycerolipid biosynthetic process#GO:0045017;cellular metabolic process#GO:0044237;glycerophospholipid metabolic process#GO:0006650;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;phospholipid metabolic process#GO:0006644;lipid biosynthetic process#GO:0008610;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;primary metabolic process#GO:0044238;glycerolipid metabolic process#GO:0046486;glycerophospholipid biosynthetic process#GO:0046474;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000006483.3|UniProtKB=F6Q106 F6Q106 LOC100184635 PTHR42807:SF1 GLUTARYL-COA DEHYDROGENASE, MITOCHONDRIAL GLUTARYL-COA DEHYDROGENASE, MITOCHONDRIAL dehydrogenase#PC00092;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000002366.3|UniProtKB=F6RA55 F6RA55 LOC100179341 PTHR12461:SF27 HYPOXIA-INDUCIBLE FACTOR 1 ALPHA INHIBITOR-RELATED JMJC DOMAIN-CONTAINING PROTEIN protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000002556.3|UniProtKB=F6UFK1 F6UFK1 LOC100182205 PTHR24253:SF55 TRANSMEMBRANE PROTEASE SERINE TRANSMEMBRANE PROTEASE SERINE 13 serine protease#PC00203;protease#PC00190 CIOIN|Ensembl=ENSCING00000020046.1|UniProtKB=H2XUZ6 H2XUZ6 PTHR16705:SF4 COMPLEXIN COMPLEXIN protein binding#GO:0005515;binding#GO:0005488;SNARE binding#GO:0000149 SNARE complex#GO:0031201;cytoplasm#GO:0005737;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;cellular anatomical entity#GO:0110165;membrane#GO:0016020;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000008093.3|UniProtKB=Q4H2P6 Q4H2P6 Ci-TGFbeta-NA2 PTHR11848:SF302 TGF-BETA FAMILY TGF-BETA FAMILY PROFILE DOMAIN-CONTAINING PROTEIN molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;cytokine activity#GO:0005125;protein binding#GO:0005515;signaling receptor binding#GO:0005102 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 CIOIN|Ensembl=ENSCING00000018041.1|UniProtKB=H2XN17 H2XN17 LOC100175061 PTHR10127:SF780 DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING METALLOENDOPEPTIDASE hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000009197.3|UniProtKB=Q67EQ6 Q67EQ6 LOC494419 PTHR12930:SF0 ZINC FINGER PROTEIN 183 RING FINGER PROTEIN 113B cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;U2-type spliceosomal complex#GO:0005684;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA splicing factor#PC00148;RNA processing factor#PC00147;RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000014441.2|UniProtKB=F6YU40 F6YU40 LOC100177822 PTHR11890:SF44 INTERLEUKIN-1 RECEPTOR FAMILY MEMBER X-LINKED INTERLEUKIN-1 RECEPTOR ACCESSORY PROTEIN-LIKE 2 transmembrane signal receptor#PC00197 CIOIN|Ensembl=ENSCING00000018880.1|UniProtKB=H2XYB1 H2XYB1 PTHR45614:SF25 MYB PROTEIN-RELATED MYB PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 CIOIN|Ensembl=ENSCING00000009575.3|UniProtKB=F6TJ76 F6TJ76 LOC113474124 PTHR11599:SF62 PROTEASOME SUBUNIT ALPHA/BETA PROTEASOME SUBUNIT BETA TYPE-3 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;peptidase complex#GO:1905368;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;proteasome complex#GO:0000502;membrane-bounded organelle#GO:0043227;endopeptidase complex#GO:1905369;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protease#PC00190;protein modifying enzyme#PC00260 Parkinson disease#P00049>20S proteasome#P01227 CIOIN|Ensembl=ENSCING00000000643.3|UniProtKB=F6RKI1 F6RKI1 PTHR46176:SF1 LD21662P LD21662P CIOIN|Ensembl=ENSCING00000021535.1|UniProtKB=H2XSE6 H2XSE6 PTHR21551:SF0 TOPOISOMERASE II-ASSOCIATED PROTEIN PAT1 PROTEIN ASSOCIATED WITH TOPO II RELATED-1, ISOFORM A RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159 negative regulation of gene expression#GO:0010629;cellular component biogenesis#GO:0044085;regulation of catabolic process#GO:0009894;heterocycle catabolic process#GO:0046700;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;nucleobase-containing compound metabolic process#GO:0006139;RNA destabilization#GO:0050779;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;P-body assembly#GO:0033962;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular component assembly#GO:0022607;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;regulation of RNA stability#GO:0043487;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;positive regulation of mRNA catabolic process#GO:0061014;regulation of cellular process#GO:0050794;post-transcriptional regulation of gene expression#GO:0010608;positive regulation of catabolic process#GO:0009896;mRNA destabilization#GO:0061157;nucleobase-containing compound catabolic process#GO:0034655;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of mRNA stability#GO:0043488;regulation of mRNA catabolic process#GO:0061013;RNA metabolic process#GO:0016070;positive regulation of cellular catabolic process#GO:0031331;cellular nitrogen compound catabolic process#GO:0044270;RNA decapping#GO:0110154;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;mRNA catabolic process#GO:0006402;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;regulation of gene expression#GO:0010468;organic substance catabolic process#GO:1901575;regulation of macromolecule biosynthetic process#GO:0010556;non-membrane-bounded organelle assembly#GO:0140694;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;positive regulation of mRNA metabolic process#GO:1903313;heterocycle metabolic process#GO:0046483;negative regulation of biosynthetic process#GO:0009890;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;organelle assembly#GO:0070925;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;positive regulation of RNA metabolic process#GO:0051254 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;P-body#GO:0000932;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic ribonucleoprotein granule#GO:0036464 RNA processing factor#PC00147 CIOIN|Ensembl=ENSCING00000023717.1|UniProtKB=Q1RL82 Q1RL82 Ci-CBF-2 PTHR46172:SF1 DNA POLYMERASE EPSILON SUBUNIT 3 DNA POLYMERASE EPSILON SUBUNIT 3 nucleic acid binding#GO:0003676;protein-containing complex binding#GO:0044877;chromatin DNA binding#GO:0031490;chromatin binding#GO:0003682;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;protein-DNA complex organization#GO:0071824;heterochromatin formation#GO:0031507;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;DNA-templated DNA replication#GO:0006261;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;negative regulation of biosynthetic process#GO:0009890;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;negative regulation of gene expression, epigenetic#GO:0045814;epigenetic regulation of gene expression#GO:0040029;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;negative regulation of macromolecule biosynthetic process#GO:0010558;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;heterochromatin organization#GO:0070828;response to stress#GO:0006950;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;protein-containing complex organization#GO:0043933;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;chromatin organization#GO:0006325;cellular response to stress#GO:0033554;chromatin remodeling#GO:0006338;DNA replication#GO:0006260;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;DNA strand elongation involved in DNA replication#GO:0006271;regulation of cellular metabolic process#GO:0031323;DNA metabolic process#GO:0006259 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-DNA complex#GO:0032993;catalytic complex#GO:1902494;chromatin#GO:0000785;transferase complex#GO:1990234;epsilon DNA polymerase complex#GO:0008622;ATPase complex#GO:1904949;intracellular organelle lumen#GO:0070013;SWI/SNF superfamily-type complex#GO:0070603;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622;DNA polymerase complex#GO:0042575;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 DNA metabolism protein#PC00009 CIOIN|Ensembl=ENSCING00000024589.1|UniProtKB=H2XKK3 H2XKK3 PTHR24300:SF397 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 2U1 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;tetrapyrrole binding#GO:0046906;steroid hydroxylase activity#GO:0008395;oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497;heme binding#GO:0020037 response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;response to chemical#GO:0042221;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 oxygenase#PC00177;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000007206.3|UniProtKB=F6Y7Q5 F6Y7Q5 th PTHR11473:SF15 AROMATIC AMINO ACID HYDROXYLASE TYROSINE 3-MONOOXYGENASE oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497 cytoplasm#GO:0005737;somatodendritic compartment#GO:0036477;cell body#GO:0044297;neuron projection#GO:0043005;neuronal cell body#GO:0043025;perikaryon#GO:0043204;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;axon#GO:0030424;intracellular anatomical structure#GO:0005622 oxidoreductase#PC00176 Dopamine receptor mediated signaling pathway#P05912>TH#P05970;Adrenaline and noradrenaline biosynthesis#P00001>TH#P00062 CIOIN|Ensembl=ENSCING00000009135.3|UniProtKB=F6S2J4 F6S2J4 PTHR24221:SF636 ATP-BINDING CASSETTE SUB-FAMILY B BILE SALT EXPORT PUMP transmembrane transporter activity#GO:0022857;primary active transmembrane transporter activity#GO:0015399;ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 localization#GO:0051179;cellular process#GO:0009987;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810 plasma membrane region#GO:0098590;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;apical part of cell#GO:0045177;plasma membrane#GO:0005886;apical plasma membrane#GO:0016324 ATP-binding cassette (ABC) transporter#PC00003;transporter#PC00227 CIOIN|Ensembl=ENSCING00000005582.3|UniProtKB=F6U3T3 F6U3T3 PTHR24351:SF110 RIBOSOMAL PROTEIN S6 KINASE NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;protein phosphorylation#GO:0006468;cellular process#GO:0009987;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;nitrogen compound metabolic process#GO:0006807;peptidyl-serine modification#GO:0018209;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 Interleukin signaling pathway#P00036>p90RSK#P00964;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>P90 RSK#P00888;PDGF signaling pathway#P00047>p90RSK#P01142 CIOIN|Ensembl=ENSCING00000019168.1|UniProtKB=H2XR56 H2XR56 PTHR23123:SF21 PHD/F-BOX CONTAINING PROTEIN JMJC DOMAIN-CONTAINING HISTONE DEMETHYLATION PROTEIN 1 histone modifying activity#GO:0140993;molecular adaptor activity#GO:0060090;demethylase activity#GO:0032451;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;histone demethylase activity#GO:0032452;catalytic activity#GO:0003824;protein-macromolecule adaptor activity#GO:0030674;catalytic activity, acting on a protein#GO:0140096 macromolecule modification#GO:0043412;regulation of DNA-templated transcription#GO:0006355;macromolecule metabolic process#GO:0043170;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;nitrogen compound metabolic process#GO:0006807;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 chromatin/chromatin-binding, or -regulatory protein#PC00077;histone modifying enzyme#PC00261 CIOIN|Ensembl=ENSCING00000020372.1|UniProtKB=H2Y084 H2Y084 PTHR36978:SF4 P-LOOP CONTAINING NUCLEOTIDE TRIPHOSPHATE HYDROLASE P-LOOP CONTAINING NUCLEOSIDE TRIPHOSPHATE HYDROLASE PROTEIN metabolite interconversion enzyme#PC00262;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000008016.3|UniProtKB=F6SSU2 F6SSU2 PTHR12558:SF9 CELL DIVISION CYCLE 16,23,27 CELL DIVISION CYCLE PROTEIN 16 HOMOLOG cell division#GO:0051301;regulation of mitotic nuclear division#GO:0007088;regulation of chromosome segregation#GO:0051983;positive regulation of organelle organization#GO:0010638;macromolecule modification#GO:0043412;regulation of chromosome separation#GO:1905818;protein catabolic process#GO:0030163;organonitrogen compound catabolic process#GO:1901565;protein modification process#GO:0036211;regulation of cellular component organization#GO:0051128;positive regulation of cell cycle#GO:0045787;post-translational protein modification#GO:0043687;modification-dependent macromolecule catabolic process#GO:0043632;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;positive regulation of cell cycle process#GO:0090068;positive regulation of mitotic cell cycle#GO:0045931;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;positive regulation of biological process#GO:0048518;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of chromosome organization#GO:0033044;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;regulation of mitotic sister chromatid separation#GO:0010965;regulation of nuclear division#GO:0051783;protein modification by small protein conjugation or removal#GO:0070647;regulation of mitotic cell cycle phase transition#GO:1901990;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;regulation of organelle organization#GO:0033043;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;positive regulation of mitotic nuclear division#GO:0045840;regulation of cell cycle phase transition#GO:1901987;organonitrogen compound metabolic process#GO:1901564;cellular process#GO:0009987;regulation of mitotic metaphase/anaphase transition#GO:0030071;primary metabolic process#GO:0044238;regulation of cell cycle process#GO:0010564;positive regulation of cellular process#GO:0048522;ubiquitin-dependent protein catabolic process#GO:0006511;anaphase-promoting complex-dependent catabolic process#GO:0031145;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;regulation of cell cycle#GO:0051726;regulation of sister chromatid segregation#GO:0033045;regulation of mitotic cell cycle#GO:0007346 ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;cullin-RING ubiquitin ligase complex#GO:0031461;transferase complex#GO:1990234;anaphase-promoting complex#GO:0005680;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;nuclear ubiquitin ligase complex#GO:0000152;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000020504.1|UniProtKB=H2XNL6 H2XNL6 PTHR19302:SF33 GAMMA TUBULIN COMPLEX PROTEIN GAMMA-TUBULIN COMPLEX COMPONENT 5 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;meiotic cell cycle#GO:0051321;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;cellular process#GO:0009987;microtubule polymerization or depolymerization#GO:0031109;chromosome segregation#GO:0007059;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;reproduction#GO:0000003;microtubule polymerization#GO:0046785;microtubule-based process#GO:0007017;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;supramolecular fiber organization#GO:0097435;sexual reproduction#GO:0019953;protein polymerization#GO:0051258;spindle assembly#GO:0051225;reproductive process#GO:0022414;cell cycle#GO:0007049;cytoskeleton organization#GO:0007010;spindle organization#GO:0007051;non-membrane-bounded organelle assembly#GO:0140694;microtubule nucleation#GO:0007020;cytoplasmic microtubule organization#GO:0031122 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 CIOIN|Ensembl=ENSCING00000002820.3|UniProtKB=F6WZ85 F6WZ85 irf-like-4 PTHR11949:SF53 INTERFERON REGULATORY FACTOR IRF TRYPTOPHAN PENTAD REPEAT DOMAIN-CONTAINING PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 CIOIN|Ensembl=ENSCING00000012468.2|UniProtKB=F6UTK0 F6UTK0 LOC100181118 PTHR23236:SF12 EUKARYOTIC TRANSLATION INITIATION FACTOR 4B/4H EUKARYOTIC INITIATION FACTOR 4B-RELATED single-stranded RNA binding#GO:0003727;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;poly(A) binding#GO:0008143;binding#GO:0005488;organic cyclic compound binding#GO:0097159 translation initiation factor#PC00224;translation factor#PC00223 CIOIN|Ensembl=ENSCING00000011828.2|UniProtKB=F6ZLV3 F6ZLV3 LOC100181710 PTHR31705:SF4 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 30 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 30 molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;protein-macromolecule adaptor activity#GO:0030674 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of RNA biosynthetic process#GO:2001141;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of RNA metabolic process#GO:0051254;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;mediator complex#GO:0016592;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031;general transcription factor#PC00259 CIOIN|Ensembl=ENSCING00000000276.3|UniProtKB=F6ZZP5 F6ZZP5 PTHR11875:SF49 TESTIS-SPECIFIC Y-ENCODED PROTEIN PROTEIN SET protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;chromatin binding#GO:0003682;histone binding#GO:0042393 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-DNA complex#GO:0032993;chromosome#GO:0005694;chromatin#GO:0000785;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 CIOIN|Ensembl=ENSCING00000008343.3|UniProtKB=F6RAS4 F6RAS4 PTHR15615:SF108 FAMILY NOT NAMED PROTEIN CNPPD1 CIOIN|Ensembl=ENSCING00000022967.1|UniProtKB=H2XUW1 H2XUW1 PTHR24112:SF66 LEUCINE-RICH REPEAT, ISOFORM F-RELATED LEUCINE-RICH REPEAT, ISOFORM F regulation of supramolecular fiber organization#GO:1902903;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;regulation of cellular process#GO:0050794;regulation of organelle organization#GO:0033043;biological regulation#GO:0065007;regulation of actin cytoskeleton organization#GO:0032956;regulation of actin filament organization#GO:0110053;regulation of cellular component organization#GO:0051128;regulation of actin filament-based process#GO:0032970;cell motility#GO:0048870;cellular process#GO:0009987;cell migration#GO:0016477 cell leading edge#GO:0031252;lamellipodium#GO:0030027;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886 protein-binding activity modulator#PC00095 CIOIN|Ensembl=ENSCING00000009508.3|UniProtKB=F7B0I1 F7B0I1 LOC100186374 PTHR10678:SF2 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 11/COP9 SIGNALOSOME COMPLEX SUBUNIT 2 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 11 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 peptidase complex#GO:1905368;protein-containing complex#GO:0032991;proteasome accessory complex#GO:0022624;proteasome regulatory particle#GO:0005838;catalytic complex#GO:1902494;proteasome regulatory particle, lid subcomplex#GO:0008541;proteasome complex#GO:0000502;endopeptidase complex#GO:1905369;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489;Cell cycle#P00013>Proteasome#P00480 CIOIN|Ensembl=ENSCING00000018315.1|UniProtKB=H2XTR1 H2XTR1 PTHR19300:SF57 BETA-1,4-GALACTOSYLTRANSFERASE BETA-1,4-N-ACETYLGALACTOSAMINYLTRANSFERASE galactosyltransferase activity#GO:0008378;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 glycosylation#GO:0070085;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000005299.3|UniProtKB=F6RUN6 F6RUN6 LOC100184515 PTHR48015:SF21 SERINE/THREONINE-PROTEIN KINASE TAO MISSHAPEN, ISOFORM A transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of MAPK cascade#GO:0043408;signal transduction#GO:0007165;neurogenesis#GO:0022008;cell projection organization#GO:0030030;macromolecule modification#GO:0043412;developmental process#GO:0032502;regulation of signaling#GO:0023051;protein modification process#GO:0036211;MAPK cascade#GO:0000165;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;regulation of intracellular signal transduction#GO:1902531;plasma membrane bounded cell projection organization#GO:0120036;phosphorus metabolic process#GO:0006793;cellular anatomical entity morphogenesis#GO:0032989;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;neuron differentiation#GO:0030182;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;plasma membrane bounded cell projection morphogenesis#GO:0120039;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular developmental process#GO:0048869;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cell communication#GO:0007154;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;cellular process#GO:0009987;primary metabolic process#GO:0044238;cell development#GO:0048468;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000016654.2|UniProtKB=F6PJS6 F6PJS6 PTHR43329:SF4 EPOXIDE HYDROLASE BIFUNCTIONAL EPOXIDE HYDROLASE 2 hydrolase activity#GO:0016787;catalytic activity#GO:0003824 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000002409.3|UniProtKB=F6QI83 F6QI83 LOC100181411 PTHR11081:SF9 FLAP ENDONUCLEASE FAMILY MEMBER FLAP ENDONUCLEASE 1 DNA endonuclease activity#GO:0004520;hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;catalytic activity#GO:0003824;endonuclease activity#GO:0004519;hydrolase activity#GO:0016787;catalytic activity, acting on a nucleic acid#GO:0140640;DNA nuclease activity#GO:0004536;catalytic activity, acting on DNA#GO:0140097 DNA metabolism protein#PC00009;exodeoxyribonuclease#PC00098 CIOIN|Ensembl=ENSCING00000013777.2|UniProtKB=F6SH63 F6SH63 LOC100176523 PTHR14520:SF4 MITOCHONDRIAL RIBOSOMAL PROTEIN 63 LARGE RIBOSOMAL SUBUNIT PROTEIN ML63 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;mitochondrial gene expression#GO:0140053;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;mitochondrial translation#GO:0032543;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;mitochondrial ribosome#GO:0005761;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;organellar ribosome#GO:0000313;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;ribosome#GO:0005840 ribosomal protein#PC00202;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000001970.3|UniProtKB=F6X4T0 F6X4T0 LOC100177158 PTHR11278:SF0 40S RIBOSOMAL PROTEIN S7 SMALL RIBOSOMAL SUBUNIT PROTEIN ES7 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;ribosomal small subunit biogenesis#GO:0042274;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 small-subunit processome#GO:0032040;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;cytosolic small ribosomal subunit#GO:0022627;preribosome#GO:0030684;small ribosomal subunit#GO:0015935;ribosome#GO:0005840;90S preribosome#GO:0030686 ribosomal protein#PC00202;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000020667.1|UniProtKB=H2Y1T8 H2Y1T8 PTHR24243:SF234 G-PROTEIN COUPLED RECEPTOR GROWTH HORMONE SECRETAGOGUE RECEPTOR TYPE 1-LIKE signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 CIOIN|Ensembl=ENSCING00000018051.1|UniProtKB=H2XK75 H2XK75 PTHR43429:SF2 PYRIDINE NUCLEOTIDE-DISULFIDE OXIDOREDUCTASE DOMAIN-CONTAINING PYRIDINE NUCLEOTIDE-DISULFIDE OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN 1 oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000004396.3|UniProtKB=F6YP38 F6YP38 LOC100186213 PTHR13160:SF4 OLIGOSACCHARYLTRANSFERASE COMPLEX SUBUNIT OSTC OLIGOSACCHARYLTRANSFERASE COMPLEX SUBUNIT OSTC membrane protein complex#GO:0098796;endoplasmic reticulum protein-containing complex#GO:0140534;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;oligosaccharyltransferase complex#GO:0008250;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000022754.1|UniProtKB=H2XUL3 H2XUL3 PTHR11119:SF122 XANTHINE-URACIL / VITAMIN C PERMEASE FAMILY MEMBER OS02G0741800 PROTEIN transporter#PC00227 CIOIN|Ensembl=ENSCING00000003863.3|UniProtKB=F6Y5S1 F6Y5S1 PTHR10334:SF590 CYSTEINE-RICH SECRETORY PROTEIN-RELATED SCP DOMAIN-CONTAINING PROTEIN extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 defense/immunity protein#PC00090 CIOIN|Ensembl=ENSCING00000014158.2|UniProtKB=F7A8H3 F7A8H3 PTHR24353:SF147 CYCLIC NUCLEOTIDE-DEPENDENT PROTEIN KINASE CGMP-DEPENDENT SERINE_THREONIN PROTEIN KINASE-RELATED non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Endothelin signaling pathway#P00019>PKG#P00567 CIOIN|Ensembl=ENSCING00000024471.1|UniProtKB=H2XQ44 H2XQ44 LOC100180291 PTHR15717:SF2 PROTEIN KIAA0494 EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 14 CIOIN|Ensembl=ENSCING00000017967.1|UniProtKB=H2XMB6 H2XMB6 PTHR24067:SF248 UBIQUITIN-CONJUGATING ENZYME E2 DORSAL INTERACTING PROTEIN 4 ubiquitin-like protein conjugating enzyme activity#GO:0061650;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;SUMO transferase activity#GO:0019789;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;protein sumoylation#GO:0016925;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000021511.1|UniProtKB=H2XRU8 H2XRU8 PTHR34759:SF1 SPERMATOGENESIS-ASSOCIATED PROTEIN 48 SPERMATOGENESIS-ASSOCIATED PROTEIN 48 CIOIN|Ensembl=ENSCING00000013206.2|UniProtKB=F6VSR6 F6VSR6 PTHR23220:SF133 INTEGRIN ALPHA INTEGRIN ALPHA-PS2 cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;integrin binding#GO:0005178;binding#GO:0005488;signaling receptor binding#GO:0005102 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cell adhesion mediated by integrin#GO:0033627;cell-cell adhesion#GO:0098609;cell communication#GO:0007154;cell adhesion#GO:0007155;cell-substrate adhesion#GO:0031589;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cell-matrix adhesion#GO:0007160;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;integrin-mediated signaling pathway#GO:0007229;biological regulation#GO:0065007;signaling#GO:0023052 receptor complex#GO:0043235;membrane protein complex#GO:0098796;external side of plasma membrane#GO:0009897;cell surface#GO:0009986;protein-containing complex#GO:0032991;plasma membrane signaling receptor complex#GO:0098802;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 cell adhesion molecule#PC00069;integrin#PC00126 Integrin signalling pathway#P00034>Integrin alpha#P00941 CIOIN|Ensembl=ENSCING00000008890.3|UniProtKB=F6QX56 F6QX56 LOC100176014 PTHR43226:SF1 XAA-PRO AMINOPEPTIDASE 3 XAA-PRO DIPEPTIDASE hydrolase activity#GO:0016787;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;metabolic process#GO:0008152;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704 metalloprotease#PC00153;protease#PC00190 CIOIN|Ensembl=ENSCING00000019964.1|UniProtKB=H2Y248 H2Y248 LOC100185173 PTHR11929:SF145 ALPHA- 1,3 -FUCOSYLTRANSFERASE ALPHA-(1,3)-FUCOSYLTRANSFERASE FUT-1 transferase activity#GO:0016740;fucosyltransferase activity#GO:0008417;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 glycosylation#GO:0070085;metabolic process#GO:0008152 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000016444.2|UniProtKB=A0A1W2WGL4 A0A1W2WGL4 LOC100185009 PTHR35378:SF1 UNNAMED PRODUCT C2H2-TYPE DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000021093.1|UniProtKB=H2Y1X5 H2Y1X5 PTHR33802:SF1 SI:CH211-161H7.5-RELATED XK-RELATED PROTEIN CIOIN|Ensembl=ENSCING00000014814.2|UniProtKB=F6SA38 F6SA38 LOC100183390 PTHR12751:SF18 PHOSPHATASE AND ACTIN REGULATOR PHACTR PHOSPHATASE AND ACTIN REGULATOR 1 phosphatase modulator#PC00184 CIOIN|Ensembl=ENSCING00000006327.3|UniProtKB=F6PYH8 F6PYH8 LOC100182277 PTHR43814:SF1 ARGININOSUCCINATE LYASE ARGININOSUCCINATE LYASE lyase activity#GO:0016829;catalytic activity#GO:0003824 organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;proteinogenic amino acid metabolic process#GO:0170039;proteinogenic amino acid biosynthetic process#GO:0170038;arginine metabolic process#GO:0006525;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;alpha-amino acid biosynthetic process#GO:1901607;nitrogen compound metabolic process#GO:0006807;amino acid biosynthetic process#GO:0008652;alpha-amino acid metabolic process#GO:1901605;small molecule biosynthetic process#GO:0044283;L-amino acid biosynthetic process#GO:0170034;carboxylic acid metabolic process#GO:0019752;L-amino acid metabolic process#GO:0170033;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 lyase#PC00144 Arginine biosynthesis#P02728>argininosuccinate lyase#P02841 CIOIN|Ensembl=ENSCING00000005508.3|UniProtKB=F7AV59 F7AV59 PTHR43968:SF6 FAMILY NOT NAMED GLUTATHIONE S-TRANSFERASE OMEGA cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000004020.3|UniProtKB=F6V9X6 F6V9X6 PTHR13617:SF14 PROTEIN ABHD18 PROTEIN ABHD18 CIOIN|Ensembl=ENSCING00000022374.1|UniProtKB=H2Y0B5 H2Y0B5 LOC113474267 PTHR10707:SF10 CYTOCHROME C OXIDASE SUBUNIT IV CYTOCHROME C OXIDASE SUBUNIT 4 mitochondrial ATP synthesis coupled electron transport#GO:0042775;aerobic respiration#GO:0009060;cellular respiration#GO:0045333;respiratory electron transport chain#GO:0022904;aerobic electron transport chain#GO:0019646;oxidative phosphorylation#GO:0006119;generation of precursor metabolites and energy#GO:0006091;electron transport chain#GO:0022900;ATP synthesis coupled electron transport#GO:0042773;cellular metabolic process#GO:0044237;cellular process#GO:0009987;mitochondrial electron transport, cytochrome c to oxygen#GO:0006123;energy derivation by oxidation of organic compounds#GO:0015980;metabolic process#GO:0008152 envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;cytochrome complex#GO:0070069;respiratory chain complex#GO:0098803;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;respirasome#GO:0070469;protein-containing complex#GO:0032991;mitochondrial envelope#GO:0005740;mitochondrial respirasome#GO:0005746;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227;respiratory chain complex IV#GO:0045277;mitochondrial protein-containing complex#GO:0098798 oxidase#PC00175;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000024804.1|UniProtKB=Q1RQ12 Q1RQ12 Ci-ZF(FYVE)-2 PTHR39490:SF8 ARRESTIN DOMAIN-CONTAINING PROTEIN D ZINC FINGER FYVE DOMAIN-CONTAINING PROTEIN 21 CIOIN|Ensembl=ENSCING00000002449.3|UniProtKB=F6QCF4 F6QCF4 PTHR11984:SF53 CONNEXIN GAP JUNCTION PROTEIN wide pore channel activity#GO:0022829;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;channel activity#GO:0015267 biological regulation#GO:0065007;regulation of biological process#GO:0050789;cell communication#GO:0007154;cellular process#GO:0009987;cell-cell signaling#GO:0007267;signaling#GO:0023052 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 cell junction protein#PC00070;gap junction#PC00105 CIOIN|Ensembl=ENSCING00000014509.2|UniProtKB=F6TMZ9 F6TMZ9 PTHR11537:SF252 VOLTAGE-GATED POTASSIUM CHANNEL POTASSIUM VOLTAGE-GATED CHANNEL PROTEIN SHAW monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;delayed rectifier potassium channel activity#GO:0005251;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated potassium channel activity#GO:0005249;transporter activity#GO:0005215;channel activity#GO:0015267;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;regulation of membrane potential#GO:0042391;action potential#GO:0001508;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;localization#GO:0051179;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;monoatomic cation transport#GO:0006812;potassium ion transmembrane transport#GO:0071805;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;potassium ion transport#GO:0006813 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;voltage-gated potassium channel complex#GO:0008076;cation channel complex#GO:0034703;plasma membrane#GO:0005886 transporter#PC00227;voltage-gated ion channel#PC00241 CIOIN|Ensembl=ENSCING00000006955.3|UniProtKB=F6V055 F6V055 PTHR11010:SF107 PROTEASE S28 PRO-X CARBOXYPEPTIDASE-RELATED DIPEPTIDYL PEPTIDASE 2 hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 serine protease#PC00203;protease#PC00190 CIOIN|Ensembl=ENSCING00000003879.3|UniProtKB=F6TXN5 F6TXN5 PTHR10371:SF3 NADH DEHYDROGENASE UBIQUINONE FLAVOPROTEIN 2, MITOCHONDRIAL NADH DEHYDROGENASE [UBIQUINONE] FLAVOPROTEIN 2, MITOCHONDRIAL NADH dehydrogenase activity#GO:0003954;oxidoreductase activity, acting on NAD(P)H#GO:0016651;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 dehydrogenase#PC00092;oxidoreductase#PC00176 Parkinson disease#P00049>Complex I#P01237 CIOIN|Ensembl=ENSCING00000024066.1|UniProtKB=H2Y3A3 H2Y3A3 PTHR31540:SF1 CENTROSOMAL PROTEIN OF 131 KDA CENTROSOMAL PROTEIN OF 131 KDA CIOIN|Ensembl=ENSCING00000018588.1|UniProtKB=H2Y3S1 H2Y3S1 PTHR15162:SF7 ASPARTOACYLASE SUCCINYLGLUTAMATE DESUCCINYLASE CIOIN|Ensembl=ENSCING00000021904.1|UniProtKB=H2XR06 H2XR06 LOC100177665 PTHR23137:SF6 VESICLE TRANSPORT PROTEIN-RELATED VESICLE TRANSPORT PROTEIN CIOIN|Ensembl=ENSCING00000008362.3|UniProtKB=F7AJZ2 F7AJZ2 PTHR12697:SF5 PBS LYASE HEAT-LIKE PROTEIN DEOXYHYPUSINE HYDROXYLASE oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 lyase#PC00144 CIOIN|Ensembl=ENSCING00000021885.1|UniProtKB=H2XKI7 H2XKI7 LOC100177679 PTHR46989:SF3 USP DOMAIN-CONTAINING PROTEIN USPA DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000019975.1|UniProtKB=H2Y1F3 H2Y1F3 PTHR24247:SF265 5-HYDROXYTRYPTAMINE RECEPTOR MUSCARINIC ACETYLCHOLINE RECEPTOR DM1 signaling receptor activity#GO:0038023;G protein-coupled amine receptor activity#GO:0008227;molecular transducer activity#GO:0060089;neurotransmitter receptor activity#GO:0030594;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 response to organic substance#GO:0010033;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to nitrogen compound#GO:1901699;response to nitrogen compound#GO:1901698;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to oxygen-containing compound#GO:1901701;chemical synaptic transmission#GO:0007268;response to chemical#GO:0042221;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;synaptic signaling#GO:0099536;G protein-coupled receptor signaling pathway#GO:0007186;cell-cell signaling#GO:0007267;signaling#GO:0023052;acetylcholine receptor signaling pathway#GO:0095500 synapse#GO:0045202;somatodendritic compartment#GO:0036477;neuron projection#GO:0043005;cell junction#GO:0030054;dendrite#GO:0030425;cell projection#GO:0042995;cell periphery#GO:0071944;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GqPCR#P00730 CIOIN|Ensembl=ENSCING00000011891.2|UniProtKB=F6WK17 F6WK17 PTHR23302:SF43 TRANSMEMBRANE CHANNEL-RELATED TMC DOMAIN-CONTAINING PROTEIN passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;channel activity#GO:0015267;gated channel activity#GO:0022836;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 ion channel#PC00133;transporter#PC00227 CIOIN|Ensembl=ENSCING00000013757.3|UniProtKB=C4B8X0 C4B8X0 Ci-NDK_DM44 PTHR43109:SF2 NUCLEOSIDE DIPHOSPHATE KINASE 7 NUCLEOSIDE DIPHOSPHATE KINASE 7 supramolecular complex#GO:0099080;axoneme#GO:0005930;cytoplasmic microtubule#GO:0005881;cytoplasmic region#GO:0099568;cellular anatomical entity#GO:0110165;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;ciliary plasm#GO:0097014;plasma membrane bounded cell projection cytoplasm#GO:0032838;cytoskeleton#GO:0005856;cell projection#GO:0042995;cilium#GO:0005929;microtubule#GO:0005874;axonemal microtubule#GO:0005879 transferase#PC00220;kinase#PC00137;metabolite interconversion enzyme#PC00262 De novo purine biosynthesis#P02738>dADP kinase#P02907;De novo purine biosynthesis#P02738>GDP kinase#P02891 CIOIN|Ensembl=ENSCING00000020402.1|UniProtKB=H2Y2V2 H2Y2V2 PTHR10579:SF172 CALCIUM-ACTIVATED CHLORIDE CHANNEL REGULATOR CALCIUM-ACTIVATED CHLORIDE CHANNEL REGULATOR 4 PRECURSOR-RELATED ion channel#PC00133;transporter#PC00227 CIOIN|Ensembl=ENSCING00000002014.3|UniProtKB=F6WST8 F6WST8 PTHR46361:SF5 ELECTRON CARRIER/ PROTEIN DISULFIDE OXIDOREDUCTASE DEP DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000016160.2|UniProtKB=F6STM9 F6STM9 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE SSU-1 sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824 cellular metabolic process#GO:0044237;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000003399.2|UniProtKB=F6ZMJ0 F6ZMJ0 LOC100184189 PTHR10522:SF5 GONADOLIBERIN PREPROGONADOTROPIN-RELEASING HORMONE 2 peptide hormone#PC00179 CIOIN|Ensembl=ENSCING00000005110.3|UniProtKB=F6WJT4 F6WJT4 LOC100180621 PTHR11360:SF284 MONOCARBOXYLATE TRANSPORTER EG:103B4.3 PROTEIN-RELATED transporter#PC00227 CIOIN|Ensembl=ENSCING00000024239.1|UniProtKB=H2XJH1 H2XJH1 PTHR10799:SF923 SNF2/RAD54 HELICASE FAMILY LYMPHOID-SPECIFIC HELICASE ATP-dependent activity, acting on DNA#GO:0008094;nucleic acid binding#GO:0003676;ATP-dependent activity#GO:0140657;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on DNA#GO:0140097 DNA helicase#PC00011;DNA metabolism protein#PC00009 Wnt signaling pathway#P00057>SWI/SNF#P01435 CIOIN|Ensembl=ENSCING00000001903.3|UniProtKB=F7A2P1 F7A2P1 LOC100180463 PTHR12907:SF26 EGL NINE HOMOLOG-RELATED HIF PROLYL HYDROXYLASE, ISOFORM C CIOIN|Ensembl=ENSCING00000004386.3|UniProtKB=F7AV03 F7AV03 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE SSU-1 sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824 cellular metabolic process#GO:0044237;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000002457.3|UniProtKB=F6Q8U3 F6Q8U3 PTHR13043:SF1 EXOCYST COMPLEX COMPONENT SEC5 EXOCYST COMPLEX COMPONENT 2 localization#GO:0051179;localization within membrane#GO:0051668;cellular localization#GO:0051641;vesicle-mediated transport to the plasma membrane#GO:0098876;exocytosis#GO:0006887;establishment of localization#GO:0051234;secretion#GO:0046903;post-Golgi vesicle-mediated transport#GO:0006892;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;Golgi to plasma membrane transport#GO:0006893;export from cell#GO:0140352;secretion by cell#GO:0032940 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;vesicle tethering complex#GO:0099023;exocyst#GO:0000145;cell cortex#GO:0005938;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 Ras Pathway#P04393>Sec5#P04545 CIOIN|Ensembl=ENSCING00000013373.2|UniProtKB=F6YE29 F6YE29 LOC100185469 PTHR33865:SF3 PROTEIN FAM183B PROTEIN FAM183B membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;cilium#GO:0005929;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;ciliary base#GO:0097546 CIOIN|Ensembl=ENSCING00000014479.2|UniProtKB=F6ZED8 F6ZED8 PTHR19325:SF567 COMPLEMENT COMPONENT-RELATED SUSHI DOMAIN-CONTAINING SUSHI, VON WILLEBRAND FACTOR TYPE A, EGF AND PENTRAXIN DOMAIN-CONTAINING PROTEIN 1-LIKE complement component#PC00078 CIOIN|Ensembl=ENSCING00000020198.1|UniProtKB=H2XKP6 H2XKP6 PTHR11127:SF2 60S RIBOSOMAL PROTEIN L14 LARGE RIBOSOMAL SUBUNIT PROTEIN EL14 structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;structural molecule activity#GO:0005198;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular component organization or biogenesis#GO:0071840;cellular component biogenesis#GO:0044085;ribosome biogenesis#GO:0042254;cellular process#GO:0009987;ribosomal large subunit biogenesis#GO:0042273;ribonucleoprotein complex biogenesis#GO:0022613 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic large ribosomal subunit#GO:0022625;large ribosomal subunit#GO:0015934;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;ribosomal subunit#GO:0044391 ribosomal protein#PC00202;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000012361.2|UniProtKB=F6SGK0 F6SGK0 PTHR24418:SF372 TYROSINE-PROTEIN KINASE TYROSINE-PROTEIN KINASE SHARK protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 non-receptor tyrosine protein kinase#PC00168 CIOIN|Ensembl=ENSCING00000009099.3|UniProtKB=F6QDJ6 F6QDJ6 LOC100183463 PTHR13377:SF3 PLACENTAL PROTEIN 6 TRANSMEMBRANE PROTEIN 115 localization#GO:0051179;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization#GO:0051234;Golgi vesicle transport#GO:0048193;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;transport#GO:0006810 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 vesicle coat protein#PC00235 CIOIN|Ensembl=ENSCING00000007636.3|UniProtKB=F6WIL6 F6WIL6 PTHR19302:SF14 GAMMA TUBULIN COMPLEX PROTEIN GAMMA-TUBULIN COMPLEX COMPONENT 3 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;meiotic cell cycle#GO:0051321;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;cellular process#GO:0009987;microtubule polymerization or depolymerization#GO:0031109;chromosome segregation#GO:0007059;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;reproduction#GO:0000003;microtubule polymerization#GO:0046785;microtubule-based process#GO:0007017;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;supramolecular fiber organization#GO:0097435;sexual reproduction#GO:0019953;protein polymerization#GO:0051258;spindle assembly#GO:0051225;reproductive process#GO:0022414;cell cycle#GO:0007049;cytoskeleton organization#GO:0007010;spindle organization#GO:0007051;non-membrane-bounded organelle assembly#GO:0140694;microtubule nucleation#GO:0007020;cytoplasmic microtubule organization#GO:0031122 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 CIOIN|Ensembl=ENSCING00000025132.1|UniProtKB=H2XXY4 H2XXY4 PTHR45762:SF3 ZINC FINGER RNA-BINDING PROTEIN ZINC-FINGER PROTEIN AT 72D, ISOFORM B RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000005119.3|UniProtKB=F6VYQ8 F6VYQ8 LOC100177375 PTHR43591:SF101 METHYLTRANSFERASE METHYLTRANSFERASE-LIKE PROTEIN 27 methyltransferase#PC00155;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000001891.3|UniProtKB=F7AKU5 F7AKU5 PTHR24255:SF31 COMPLEMENT COMPONENT 1, S SUBCOMPONENT-RELATED CUBILIN-LIKE PROTEIN hydrolase activity#GO:0016787;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 serine protease#PC00203;protease#PC00190 CIOIN|Ensembl=ENSCING00000004023.3|UniProtKB=F6V9Y2 F6V9Y2 PTHR11827:SF6 SOLUTE CARRIER FAMILY 12, CATION COTRANSPORTERS SOLUTE CARRIER FAMILY 12 MEMBER 8 inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium ion transmembrane transporter activity#GO:0015079;symporter activity#GO:0015293;chloride transmembrane transporter activity#GO:0015108;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;active monoatomic ion transmembrane transporter activity#GO:0022853;monoatomic anion transmembrane transporter activity#GO:0008509;inorganic anion transmembrane transporter activity#GO:0015103;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294 inorganic ion homeostasis#GO:0098771;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;chloride transmembrane transport#GO:1902476;inorganic ion transmembrane transport#GO:0098660;cellular homeostasis#GO:0019725;inorganic anion transmembrane transport#GO:0098661;import across plasma membrane#GO:0098739;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;monoatomic cation transport#GO:0006812;inorganic anion transport#GO:0015698;potassium ion transport#GO:0006813;regulation of anatomical structure size#GO:0090066;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;monoatomic anion transmembrane transport#GO:0098656;chloride transport#GO:0006821;homeostatic process#GO:0042592;monoatomic cation homeostasis#GO:0055080;cellular component organization#GO:0016043;cellular process#GO:0009987;chemical homeostasis#GO:0048878;regulation of cellular component size#GO:0032535;monoatomic ion homeostasis#GO:0050801;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;regulation of cell size#GO:0008361;monoatomic ion transmembrane transport#GO:0034220;monoatomic anion transport#GO:0006820;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;import into cell#GO:0098657;potassium ion import across plasma membrane#GO:1990573 secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000003818.3|UniProtKB=F6ZT48 F6ZT48 PTHR11863:SF226 STEROL DESATURASE FATTY ACID HYDROXYLASE DOMAIN-CONTAINING PROTEIN 2-RELATED oxidase#PC00175;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000000711.3|UniProtKB=F6Q5D4 F6Q5D4 LOC100180226 PTHR45918:SF1 ALPHA-1,3/1,6-MANNOSYLTRANSFERASE ALG2 ALPHA-1,3_1,6-MANNOSYLTRANSFERASE ALG2 transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000006405.3|UniProtKB=F6X6Q2 F6X6Q2 LOC100179428 PTHR10699:SF11 NEUROMODULIN IGLOO, ISOFORM A protein binding#GO:0005515;calmodulin binding#GO:0005516;binding#GO:0005488 CIOIN|Ensembl=ENSCING00000019654.1|UniProtKB=H2XZ00 H2XZ00 LOC100184533 PTHR34094:SF1 FAMILY NOT NAMED PROTEIN FAM185A CIOIN|Ensembl=ENSCING00000003584.3|UniProtKB=F6Y886 F6Y886 PTHR46231:SF1 ANKYRIN REPEAT AND BTB/POZ DOMAIN-CONTAINING PROTEIN 1 ANKYRIN REPEAT AND BTB_POZ DOMAIN-CONTAINING PROTEIN 1 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000002688.3|UniProtKB=F6Z442 F6Z442 PTHR19143:SF459 FIBRINOGEN/TENASCIN/ANGIOPOEITIN FIBRINOGEN C-TERMINAL DOMAIN-CONTAINING PROTEIN external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 CIOIN|Ensembl=ENSCING00000018757.1|UniProtKB=H2XX89 H2XX89 LOC100183559 PTHR24228:SF74 B2 BRADYKININ RECEPTOR/ANGIOTENSIN II RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 G-protein coupled receptor#PC00021 CIOIN|Ensembl=ENSCING00000012518.2|UniProtKB=F7BDS7 F7BDS7 LOC100184230 PTHR13384:SF19 G PATCH DOMAIN-CONTAINING PROTEIN 1 G PATCH DOMAIN-CONTAINING PROTEIN 1 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000014552.1|UniProtKB=L7N0V1 L7N0V1 LOC778624 PTHR10811:SF5 FRINGE-RELATED FRINGE GLYCOSYLTRANSFERASE acetylglucosaminyltransferase activity#GO:0008375;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194;hexosyltransferase activity#GO:0016758 glycosyltransferase#PC00111;metabolite interconversion enzyme#PC00262 Notch signaling pathway#P00045>Fringe#P01107 CIOIN|Ensembl=ENSCING00000002139.3|UniProtKB=F6W5B3 F6W5B3 LOC100184970 PTHR21064:SF1 AMINOGLYCOSIDE PHOSPHOTRANSFERASE DOMAIN-CONTAINING PROTEIN-RELATED HYDROXYLYSINE KINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301 CIOIN|Ensembl=ENSCING00000008907.3|UniProtKB=F6QBE1 F6QBE1 PTHR12863:SF1 FATTY ACID HYDROXYLASE FATTY ACID 2-HYDROXYLASE hydroxylase#PC00122 CIOIN|Ensembl=ENSCING00000008132.3|UniProtKB=F6W2G3 F6W2G3 LOC100177170 PTHR43725:SF47 UDP-GLUCOSE 4-EPIMERASE UDP-GLUCOSE 4-EPIMERASE racemase and epimerase activity, acting on carbohydrates and derivatives#GO:0016857;isomerase activity#GO:0016853;catalytic activity#GO:0003824 monosaccharide metabolic process#GO:0005996;carbohydrate metabolic process#GO:0005975;organic substance metabolic process#GO:0071704;primary metabolic process#GO:0044238;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 epimerase/racemase#PC00096;metabolite interconversion enzyme#PC00262 Fructose galactose metabolism#P02744>UDP Glucose 4 epimerase#P02965 CIOIN|Ensembl=ENSCING00000005201.3|UniProtKB=F6S8I5 F6S8I5 fz3_6 PTHR11309:SF47 FRIZZLED FRIZZLED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;protein binding#GO:0005515;Wnt-protein binding#GO:0017147;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;non-canonical Wnt signaling pathway#GO:0035567;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;cell-cell signaling by wnt#GO:0198738;canonical Wnt signaling pathway#GO:0060070;cell-cell signaling#GO:0007267;signaling#GO:0023052;Wnt signaling pathway#GO:0016055 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Angiogenesis#P00005>Fzd#P00189;Wnt signaling pathway#P00057>Frizzled#P01428;Alzheimer disease-presenilin pathway#P00004>Frizzled#P00119;Cadherin signaling pathway#P00012>Frizzled#P00475 CIOIN|Ensembl=ENSCING00000018895.1|UniProtKB=H2Y0R2 H2Y0R2 LOC100179093 PTHR11669:SF9 REPLICATION FACTOR C / DNA POLYMERASE III GAMMA-TAU SUBUNIT REPLICATION FACTOR C SUBUNIT 5 ATP-dependent activity, acting on DNA#GO:0008094;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on DNA#GO:0140097;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;response to stress#GO:0006950;nitrogen compound metabolic process#GO:0006807;DNA-templated DNA replication#GO:0006261;DNA replication#GO:0006260;cellular response to stress#GO:0033554;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;replication fork#GO:0005657 DNA-directed DNA polymerase#PC00018 DNA replication#P00017>RFC#P00529 CIOIN|Ensembl=ENSCING00000012700.2|UniProtKB=F6TEX9 F6TEX9 PTHR23320:SF162 MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MS4A -RELATED EXPRESSED PROTEIN transporter#PC00227 CIOIN|Ensembl=ENSCING00000017560.1|UniProtKB=F6ZYN8 F6ZYN8 PTHR13215:SF0 RNA POLYMERASE II TRANSCRIPTIONAL COACTIVATOR ACTIVATED RNA POLYMERASE II TRANSCRIPTIONAL COACTIVATOR P15 transcription coactivator activity#GO:0003713;molecular adaptor activity#GO:0060090;transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;protein-macromolecule adaptor activity#GO:0030674 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031;general transcription factor#PC00259 CIOIN|Ensembl=ENSCING00000004829.3|UniProtKB=F6R8N5 F6R8N5 PTHR24286:SF384 CYTOCHROME P450 26 P450, PUTATIVE (EUROFUNG)-RELATED oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497 sterol metabolic process#GO:0016125;organic hydroxy compound metabolic process#GO:1901615;lipid metabolic process#GO:0006629;steroid metabolic process#GO:0008202;organic cyclic compound metabolic process#GO:1901360;metabolic process#GO:0008152;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704 oxygenase#PC00177;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000006860.2|UniProtKB=F6ZX23 F6ZX23 LOC100185453 PTHR24068:SF41 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2-24 KDA ubiquitin-like protein conjugating enzyme activity#GO:0061650;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin conjugating enzyme activity#GO:0061631;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein polyubiquitination#GO:0000209;post-translational protein modification#GO:0043687;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 Ubiquitin proteasome pathway#P00060>E2#P01491 CIOIN|Ensembl=ENSCING00000018711.1|UniProtKB=F6Y5B7 F6Y5B7 LOC100185831 PTHR24068:SF526 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2D 4 LIKE 1 ubiquitin-like protein conjugating enzyme activity#GO:0061650;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;ubiquitin-like protein ligase binding#GO:0044389;enzyme binding#GO:0019899;ubiquitin conjugating enzyme activity#GO:0061631;protein binding#GO:0005515;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin protein ligase binding#GO:0031625 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein K48-linked ubiquitination#GO:0070936;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein polyubiquitination#GO:0000209;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 Ubiquitin proteasome pathway#P00060>E2#P01491 CIOIN|Ensembl=ENSCING00000005083.3|UniProtKB=F7B2L3 F7B2L3 LOC100183019 PTHR11880:SF2 RIBOSOMAL PROTEIN S19P FAMILY MEMBER SMALL RIBOSOMAL SUBUNIT PROTEIN US19 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;protein-RNA complex assembly#GO:0022618;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;ribonucleoprotein complex biogenesis#GO:0022613;protein-containing complex assembly#GO:0065003;ribosome biogenesis#GO:0042254;cellular component organization#GO:0016043;protein-RNA complex organization#GO:0071826;non-membrane-bounded organelle assembly#GO:0140694;cellular process#GO:0009987;ribosomal small subunit biogenesis#GO:0042274 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic small ribosomal subunit#GO:0022627;cytosol#GO:0005829;small ribosomal subunit#GO:0015935;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000002854.3|UniProtKB=F6TN28 F6TN28 PTHR12149:SF8 FRUCTOSAMINE 3 KINASE-RELATED PROTEIN PROTEIN-RIBULOSAMINE 3-KINASE transferase#PC00220;kinase#PC00137;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000012896.2|UniProtKB=F6PTJ9 F6PTJ9 PTHR13832:SF803 PROTEIN PHOSPHATASE 2C PROTEIN PHOSPHATASE 1G macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;dephosphorylation#GO:0016311;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein dephosphorylation#GO:0006470;cellular metabolic process#GO:0044237;cellular process#GO:0009987;protein metabolic process#GO:0019538;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 protein phosphatase#PC00195;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000023768.1|UniProtKB=H2XVX8 H2XVX8 LOC100180756 PTHR24073:SF1223 DRAB5-RELATED LD47384P GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824 localization#GO:0051179;organic substance transport#GO:0071702;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;transport#GO:0006810;protein transport#GO:0015031;nitrogen compound transport#GO:0071705;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104 cellular anatomical entity#GO:0110165;endomembrane system#GO:0012505 small GTPase#PC00208;G-protein#PC00020 CIOIN|Ensembl=ENSCING00000004283.3|UniProtKB=F6UGG0 F6UGG0 PTHR14024:SF49 PERILIPIN LIPID STORAGE DROPLETS SURFACE-BINDING PROTEIN 1 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000002876.3|UniProtKB=F6T0U6 F6T0U6 PTHR11247:SF27 PALMITOYL-PROTEIN THIOESTERASE/DOLICHYLDIPHOSPHATASE 1 LYSOSOMAL THIOESTERASE PPT2 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;thiolester hydrolase activity#GO:0016790 cytoplasm#GO:0005737;lysosome#GO:0005764;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;lytic vacuole#GO:0000323;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000024826.1|UniProtKB=F6W310 F6W310 LOC100178125 PTHR12919:SF20 30S RIBOSOMAL PROTEIN S16 SMALL RIBOSOMAL SUBUNIT PROTEIN BS16M structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;small ribosomal subunit#GO:0015935;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000023171.1|UniProtKB=H2XR21 H2XR21 PTHR10036:SF3 CD59 GLYCOPROTEIN PROTEIN SLEEPLESS-RELATED CIOIN|Ensembl=ENSCING00000012801.2|UniProtKB=F7AA47 F7AA47 PTHR35538:SF6 LIG_CHAN-GLU_BD DOMAIN-CONTAINING PROTEIN EF-HAND DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000023704.1|UniProtKB=H2Y171 H2Y171 PTHR24300:SF397 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 2U1 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;tetrapyrrole binding#GO:0046906;steroid hydroxylase activity#GO:0008395;oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497;heme binding#GO:0020037 response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;response to chemical#GO:0042221;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 oxygenase#PC00177;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000023856.1|UniProtKB=F6WL19 F6WL19 PTHR18860:SF17 14-3-3 PROTEIN 14-3-3 PROTEIN EPSILON localization#GO:0051179;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular localization#GO:0051641;cellular response to stimulus#GO:0051716;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052;protein localization#GO:0008104 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 Parkinson disease#P00049>14-3-3#P01238;FGF signaling pathway#P00021>14-3-3#P00624;EGF receptor signaling pathway#P00018>14-3-3#P00539 CIOIN|Ensembl=ENSCING00000008384.3|UniProtKB=F7A160 F7A160 LOC100181257 PTHR10414:SF71 ETHANOLAMINEPHOSPHOTRANSFERASE FI05338P transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;phospholipid biosynthetic process#GO:0008654;organophosphate biosynthetic process#GO:0090407;glycerolipid biosynthetic process#GO:0045017;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;glycerophospholipid metabolic process#GO:0006650;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;glycerophospholipid biosynthetic process#GO:0046474;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000005310.3|UniProtKB=F7BQ61 F7BQ61 LOC100178239 PTHR23035:SF2 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 97-RELATED KIAA1430 HOMOLOGUE CIOIN|Ensembl=ENSCING00000008084.3|UniProtKB=F6Z6L1 F6Z6L1 syn PTHR10841:SF17 SYNAPSIN SYNAPSIN neurotransmitter secretion#GO:0007269;cellular localization#GO:0051641;transport#GO:0006810;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;localization#GO:0051179;regulation of biological process#GO:0050789;signal release from synapse#GO:0099643;chemical synaptic transmission#GO:0007268;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;secretion#GO:0046903;neurotransmitter transport#GO:0006836;biological regulation#GO:0065007;signal release#GO:0023061;synaptic signaling#GO:0099536;establishment of localization in cell#GO:0051649;signaling#GO:0023052;cell-cell signaling#GO:0007267;export from cell#GO:0140352;secretion by cell#GO:0032940 synaptic vesicle membrane#GO:0030672;bounding membrane of organelle#GO:0098588;presynapse#GO:0098793;synapse#GO:0045202;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;synaptic vesicle#GO:0008021;cell junction#GO:0030054;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;transport vesicle membrane#GO:0030658;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;transport vesicle#GO:0030133;cytoplasmic vesicle membrane#GO:0030659;secretory vesicle#GO:0099503 membrane trafficking regulatory protein#PC00151 Synaptic vesicle trafficking#P05734>Synapsin#P05775 CIOIN|Ensembl=ENSCING00000012657.2|UniProtKB=H2XME2 H2XME2 PTHR13273:SF14 ANAMORSIN ANAMORSIN cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;iron-sulfur cluster assembly#GO:0016226;cellular component organization#GO:0016043;cellular process#GO:0009987 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000004496.3|UniProtKB=F6TF16 F6TF16 LOC100186170 PTHR23320:SF165 MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MS4A -RELATED MARVEL DOMAIN-CONTAINING PROTEIN transporter#PC00227 CIOIN|Ensembl=ENSCING00000011881.2|UniProtKB=F6YJG1 F6YJG1 PTHR15175:SF0 NEUTROPHIL CYTOSOLIC FACTOR 2, NEUTROPHIL NADPH OXIDASE FACTOR 2 SH3 DOMAIN-CONTAINING PROTEIN C23A1.17 protein-binding activity modulator#PC00095 CIOIN|Ensembl=ENSCING00000003993.3|UniProtKB=F6WKB8 F6WKB8 PTHR13194:SF18 COMPLEX I INTERMEDIATE-ASSOCIATED PROTEIN 30 COMPLEX I INTERMEDIATE-ASSOCIATED PROTEIN 30, MITOCHONDRIAL protein binding#GO:0005515;unfolded protein binding#GO:0051082;binding#GO:0005488 aerobic respiration#GO:0009060;cellular respiration#GO:0045333;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrial electron transport, NADH to ubiquinone#GO:0006120;aerobic electron transport chain#GO:0019646;generation of precursor metabolites and energy#GO:0006091;protein-containing complex assembly#GO:0065003;electron transport chain#GO:0022900;ATP synthesis coupled electron transport#GO:0042773;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular process#GO:0009987;energy derivation by oxidation of organic compounds#GO:0015980;cellular component organization or biogenesis#GO:0071840;mitochondrial ATP synthesis coupled electron transport#GO:0042775;mitochondrial respiratory chain complex I assembly#GO:0032981;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;respiratory electron transport chain#GO:0022904;oxidative phosphorylation#GO:0006119;mitochondrion organization#GO:0007005;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000005153.3|UniProtKB=F6SKU8 F6SKU8 PTHR10066:SF67 BETA-GLUCURONIDASE BETA-GLUCURONIDASE carbohydrate derivative metabolic process#GO:1901135;glycosyl compound catabolic process#GO:1901658;carbohydrate derivative catabolic process#GO:1901136;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;glycosyl compound metabolic process#GO:1901657;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 CIOIN|Ensembl=ENSCING00000022465.1|UniProtKB=A0A1W3JQF8 A0A1W3JQF8 LOC100180090 PTHR12300:SF117 HVA22-LIKE PROTEINS LP05237P-RELATED membrane traffic protein#PC00150 CIOIN|Ensembl=ENSCING00000003933.3|UniProtKB=F7A568 F7A568 PTHR11339:SF402 EXTRACELLULAR MATRIX GLYCOPROTEIN RELATED VWFD DOMAIN-CONTAINING PROTEIN extracellular matrix protein#PC00102 CIOIN|Ensembl=ENSCING00000010230.3|UniProtKB=F6QXN6 F6QXN6 PTHR11176:SF57 BOULE-RELATED PROTEIN BOULE RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000008612.3|UniProtKB=F6TNU2 F6TNU2 LOC100176285 PTHR10889:SF3 DEOXYRIBOSE-PHOSPHATE ALDOLASE DEOXYRIBOSE-PHOSPHATE ALDOLASE lyase activity#GO:0016829;carbon-carbon lyase activity#GO:0016830;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;heterocycle catabolic process#GO:0046700;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;cellular nitrogen compound catabolic process#GO:0044270;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;carbohydrate catabolic process#GO:0016052;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carbohydrate metabolic process#GO:0005975;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248;heterocycle metabolic process#GO:0046483;nucleoside phosphate catabolic process#GO:1901292;carbohydrate derivative catabolic process#GO:1901136;cellular metabolic process#GO:0044237;nucleotide catabolic process#GO:0009166;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organophosphate catabolic process#GO:0046434;primary metabolic process#GO:0044238;aromatic compound catabolic process#GO:0019439;organic cyclic compound catabolic process#GO:1901361;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;nucleotide metabolic process#GO:0009117;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 aldolase#PC00044;lyase#PC00144 CIOIN|Ensembl=ENSCING00000012493.2|UniProtKB=A0A1W2WP01 A0A1W2WP01 LOC100186610 PTHR10705:SF0 DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT DAD1 DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT DAD1 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein N-linked glycosylation#GO:0006487;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 membrane protein complex#GO:0098796;endoplasmic reticulum protein-containing complex#GO:0140534;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endoplasmic reticulum subcompartment#GO:0098827;oligosaccharyltransferase complex#GO:0008250;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 glycosyltransferase#PC00111 CIOIN|Ensembl=ENSCING00000023580.1|UniProtKB=H2XQ29 H2XQ29 LOC100179603 PTHR46317:SF1 HYDROLASE OF PHP SUPERFAMILY-RELATED PROTEIN HYDROLASE, TATD FAMILY metabolite interconversion enzyme#PC00262;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000008783.3|UniProtKB=F6SDE2 F6SDE2 LOC100175472 PTHR10677:SF3 UBIQUILIN FI07626P-RELATED protein binding#GO:0005515;binding#GO:0005488;polyubiquitin modification-dependent protein binding#GO:0031593;modification-dependent protein binding#GO:0140030 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000009366.3|UniProtKB=F6WYD9 F6WYD9 PTHR10878:SF22 SEGMENT POLARITY PROTEIN DISHEVELLED DIXIN regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;cell-cell signaling by wnt#GO:0198738;canonical Wnt signaling pathway#GO:0060070;cell-cell signaling#GO:0007267;signaling#GO:0023052;Wnt signaling pathway#GO:0016055 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000023648.1|UniProtKB=H2XK49 H2XK49 LOC100186945 PTHR22146:SF8 CAT EYE SYNDROME CRITICAL REGION PROTEIN 6 PROTEIN FAM166B CIOIN|Ensembl=ENSCING00000007852.3|UniProtKB=H2XTT5 H2XTT5 LOC100181589 PTHR13677:SF0 LD41638P LD41638P cytoplasm#GO:0005737;endosome#GO:0005768;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;recycling endosome#GO:0055037;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000012609.2|UniProtKB=F6XEM8 F6XEM8 PTHR11929:SF145 ALPHA- 1,3 -FUCOSYLTRANSFERASE ALPHA-(1,3)-FUCOSYLTRANSFERASE FUT-1 transferase activity#GO:0016740;fucosyltransferase activity#GO:0008417;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 glycosylation#GO:0070085;metabolic process#GO:0008152 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000000960.3|UniProtKB=F7BAJ6 F7BAJ6 PTHR46806:SF5 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN F5_8 TYPE C DOMAIN-CONTAINING PROTEIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 CIOIN|Ensembl=ENSCING00000017012.2|UniProtKB=F7A0M9 F7A0M9 PTHR24300:SF397 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 2U1 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;tetrapyrrole binding#GO:0046906;steroid hydroxylase activity#GO:0008395;oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497;heme binding#GO:0020037 response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;response to chemical#GO:0042221;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 oxygenase#PC00177;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000012420.2|UniProtKB=F6Y5E2 F6Y5E2 PTHR12448:SF0 ATP SYNTHASE EPSILON CHAIN, MITOCHONDRIAL ATP SYNTHASE SUBUNIT EPSILON, MITOCHONDRIAL monoatomic cation channel activity#GO:0005261;ligase activity#GO:0016874;inorganic molecular entity transmembrane transporter activity#GO:0015318;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;catalytic activity#GO:0003824;proton transmembrane transporter activity#GO:0015078;proton channel activity#GO:0015252;proton-transporting ATP synthase activity, rotational mechanism#GO:0046933;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;inorganic cation transmembrane transporter activity#GO:0022890;channel activity#GO:0015267;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 cellular aromatic compound metabolic process#GO:0006725;ribonucleoside triphosphate metabolic process#GO:0009199;nucleoside triphosphate metabolic process#GO:0009141;carbohydrate derivative metabolic process#GO:1901135;ATP biosynthetic process#GO:0006754;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;energy derivation by oxidation of organic compounds#GO:0015980;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ATP metabolic process#GO:0046034;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;purine nucleoside triphosphate biosynthetic process#GO:0009145;aerobic respiration#GO:0009060;cellular respiration#GO:0045333;heterocycle metabolic process#GO:0046483;purine ribonucleoside triphosphate metabolic process#GO:0009205;generation of precursor metabolites and energy#GO:0006091;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;ribonucleoside triphosphate biosynthetic process#GO:0009201;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;proton motive force-driven ATP synthesis#GO:0015986;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;oxidative phosphorylation#GO:0006119;aromatic compound biosynthetic process#GO:0019438;nucleoside triphosphate biosynthetic process#GO:0009142;organophosphate metabolic process#GO:0019637;purine nucleoside triphosphate metabolic process#GO:0009144;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 envelope#GO:0031975;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227 ATP synthase#PC00002;primary active transporter#PC00068;transporter#PC00227 CIOIN|Ensembl=ENSCING00000005423.3|UniProtKB=F6YQ60 F6YQ60 PTHR45738:SF5 POLYPHOSPHOINOSITIDE PHOSPHATASE POLYPHOSPHOINOSITIDE PHOSPHATASE hydrolase activity#GO:0016787;phosphatidylinositol-3,5-bisphosphate phosphatase activity#GO:0106018;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 phospholipid dephosphorylation#GO:0046839;lipid metabolic process#GO:0006629;phosphatidylinositol dephosphorylation#GO:0046856;cellular metabolic process#GO:0044237;phosphatidylinositol metabolic process#GO:0046488;glycerophospholipid metabolic process#GO:0006650;lipid modification#GO:0030258;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;dephosphorylation#GO:0016311;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;phosphatase#PC00181;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000004473.3|UniProtKB=F6U4I8 F6U4I8 PTHR35001:SF4 COLLAGEN IV NC1 DOMAIN-CONTAINING PROTEIN SUBFAMILY NOT NAMED CIOIN|Ensembl=ENSCING00000009558.3|UniProtKB=F6U7X2 F6U7X2 PTHR23086:SF101 PHOSPHATIDYLINOSITOL-4-PHOSPHATE 5-KINASE LP03320P-RELATED transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301;lipid kinase activity#GO:0001727 lipid metabolic process#GO:0006629;phospholipid biosynthetic process#GO:0008654;organophosphate biosynthetic process#GO:0090407;phosphatidylinositol biosynthetic process#GO:0006661;glycerolipid biosynthetic process#GO:0045017;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;phosphatidylinositol metabolic process#GO:0046488;glycerophospholipid metabolic process#GO:0006650;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;phosphatidylinositol phosphate biosynthetic process#GO:0046854;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;glycerophospholipid biosynthetic process#GO:0046474;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 kinase#PC00137 CIOIN|Ensembl=ENSCING00000013055.2|UniProtKB=F6T526 F6T526 PTHR10426:SF88 STRICTOSIDINE SYNTHASE-RELATED ADIPOCYTE PLASMA MEMBRANE-ASSOCIATED PROTEIN HEMOMUCIN-RELATED hydrolase activity#GO:0016787;catalytic activity#GO:0003824 CIOIN|Ensembl=ENSCING00000008025.3|UniProtKB=F6SSK4 F6SSK4 PTHR15108:SF0 N-ACYLGLUCOSAMINE-2-EPIMERASE N-ACYLGLUCOSAMINE 2-EPIMERASE racemase and epimerase activity, acting on carbohydrates and derivatives#GO:0016857;isomerase activity#GO:0016853;catalytic activity#GO:0003824 amino sugar metabolic process#GO:0006040;carbohydrate derivative metabolic process#GO:1901135;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 epimerase/racemase#PC00096;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000006536.3|UniProtKB=F6RNS7 F6RNS7 LOC100180144 PTHR23074:SF83 AAA DOMAIN-CONTAINING VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 4A cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 CIOIN|Ensembl=ENSCING00000023710.1|UniProtKB=H2XN22 H2XN22 PTHR11819:SF150 SOLUTE CARRIER FAMILY 5 SODIUM_MYO-INOSITOL COTRANSPORTER inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;carbohydrate transmembrane transporter activity#GO:0015144;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;sugar transmembrane transporter activity#GO:0051119;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;active transmembrane transporter activity#GO:0022804;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;active monoatomic ion transmembrane transporter activity#GO:0022853;monoatomic ion transmembrane transporter activity#GO:0015075;inorganic cation transmembrane transporter activity#GO:0022890;solute:monoatomic cation symporter activity#GO:0015294 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000011389.2|UniProtKB=F6TJA8 F6TJA8 LOC100179157 PTHR14735:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 134 COILED-COIL DOMAIN-CONTAINING PROTEIN 134 CIOIN|Ensembl=ENSCING00000005280.3|UniProtKB=F6UIA2 F6UIA2 PTHR11006:SF4 PROTEIN ARGININE N-METHYLTRANSFERASE PROTEIN ARGININE N-METHYLTRANSFERASE 7 N-methyltransferase activity#GO:0008170;histone modifying activity#GO:0140993;transferase activity#GO:0016740;catalytic activity#GO:0003824;histone methyltransferase activity#GO:0042054;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a protein#GO:0140096;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;protein methyltransferase activity#GO:0008276 protein-DNA complex organization#GO:0071824;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular component organization#GO:0016043;peptidyl-amino acid modification#GO:0018193;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;methylation#GO:0032259;macromolecule methylation#GO:0043414;nitrogen compound metabolic process#GO:0006807;protein-containing complex organization#GO:0043933;chromatin organization#GO:0006325;chromatin remodeling#GO:0006338;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000014988.2|UniProtKB=F6UV96 F6UV96 PTHR22802:SF456 C-TYPE LECTIN SUPERFAMILY MEMBER FI01427P membrane traffic protein#PC00150 CIOIN|Ensembl=ENSCING00000005906.3|UniProtKB=F6SH21 F6SH21 LOC100180658 PTHR22776:SF97 MARVEL-CONTAINING POTENTIAL LIPID RAFT-ASSOCIATED PROTEIN RE01453P cellular anatomical entity#GO:0110165;membrane#GO:0016020 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000010297.3|UniProtKB=F6Q671 F6Q671 PTHR22906:SF48 PROPERDIN THROMBOSPONDIN TYPE 1 DOMAIN PROTEIN CIOIN|Ensembl=ENSCING00000024747.1|UniProtKB=H2XYG4 H2XYG4 LOC100177927 PTHR21346:SF0 FUN14 DOMAIN CONTAINING RE45833P process utilizing autophagic mechanism#GO:0061919;cellular component organization or biogenesis#GO:0071840;cellular component disassembly#GO:0022411;organelle organization#GO:0006996;catabolic process#GO:0009056;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;autophagy of mitochondrion#GO:0000422;mitochondrion organization#GO:0007005;cellular process#GO:0009987;organelle disassembly#GO:1903008;autophagy#GO:0006914;cellular catabolic process#GO:0044248;metabolic process#GO:0008152 envelope#GO:0031975;bounding membrane of organelle#GO:0098588;mitochondrial membrane#GO:0031966;intracellular membrane-bounded organelle#GO:0043231;mitochondrial outer membrane#GO:0005741;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867 CIOIN|Ensembl=ENSCING00000022065.1|UniProtKB=H2XMT1 H2XMT1 PTHR11360:SF284 MONOCARBOXYLATE TRANSPORTER EG:103B4.3 PROTEIN-RELATED transporter#PC00227 CIOIN|Ensembl=ENSCING00000011724.2|UniProtKB=F6W023 F6W023 pias PTHR10782:SF94 ZINC FINGER MIZ DOMAIN-CONTAINING PROTEIN SUPPRESSOR OF VARIEGATION 2-10, ISOFORM I molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;SUMO transferase activity#GO:0019789;protein-macromolecule adaptor activity#GO:0030674;ubiquitin-like protein ligase activity#GO:0061659;SUMO ligase activity#GO:0061665;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;regulation of DNA-templated transcription#GO:0006355;macromolecule metabolic process#GO:0043170;regulation of nitrogen compound metabolic process#GO:0051171;protein sumoylation#GO:0016925;regulation of transcription by RNA polymerase II#GO:0006357;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;regulation of RNA biosynthetic process#GO:2001141;post-translational protein modification#GO:0043687;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromatin#GO:0000785;protein-DNA complex#GO:0032993;chromosome#GO:0005694;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 Interferon-gamma signaling pathway#P00035>PIAS#P00958 CIOIN|Ensembl=ENSCING00000009663.3|UniProtKB=F6W6V6 F6W6V6 LOC100180899 PTHR10514:SF27 ANGIOTENSIN-CONVERTING ENZYME ANGIOTENSIN-CONVERTING ENZYME metalloprotease#PC00153;protease#PC00190 CIOIN|Ensembl=ENSCING00000013862.2|UniProtKB=F6QG49 F6QG49 PTHR31302:SF0 TRANSMEMBRANE PROTEIN WITH METALLOPHOSPHOESTERASE DOMAIN-RELATED TRANSMEMBRANE PROTEIN WITH METALLOPHOSPHOESTERASE DOMAIN CIOIN|Ensembl=ENSCING00000000490.3|UniProtKB=F6YCG7 F6YCG7 PTHR45627:SF1 ADENYLATE CYCLASE TYPE 1 ADENYLATE CYCLASE TYPE 8 adenylate cyclase activity#GO:0004016;lyase activity#GO:0016829;cyclase activity#GO:0009975;phosphorus-oxygen lyase activity#GO:0016849;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;signal transduction#GO:0007165;cyclic nucleotide metabolic process#GO:0009187;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;signaling#GO:0023052;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cellular response to stimulus#GO:0051716;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cell communication#GO:0007154;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;response to stimulus#GO:0050896;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cyclase#PC00079;adenylate cyclase#PC00043;lyase#PC00144 Endothelin signaling pathway#P00019>Adenylate cyclase#P00569;GABA-B receptor II signaling#P05731>AC#P05760;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>cAMP cyclase#P00719 CIOIN|Ensembl=ENSCING00000019085.1|UniProtKB=H2XLQ4 H2XLQ4 PTHR34644:SF2 SINGLE-PASS MEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 4 SINGLE-PASS MEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 4 CIOIN|Ensembl=ENSCING00000006613.3|UniProtKB=F6QPP6 F6QPP6 LOC100185665 PTHR31954:SF1 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 157 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 157 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;microtubule cytoskeleton#GO:0015630;ciliary basal body#GO:0036064;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cilium#GO:0005929;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 structural protein#PC00211 CIOIN|Ensembl=ENSCING00000012193.2|UniProtKB=F7AG76 F7AG76 PTHR21738:SF0 RIBOSOMAL RNA PROCESSING PROTEIN 36 HOMOLOG RIBOSOMAL RNA PROCESSING PROTEIN 36 HOMOLOG cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;maturation of SSU-rRNA#GO:0030490;ribosomal small subunit biogenesis#GO:0042274;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;nuclear lumen#GO:0031981;90S preribosome#GO:0030686 CIOIN|Ensembl=ENSCING00000003558.3|UniProtKB=F6YTA1 F6YTA1 PTHR31344:SF0 NUCLEAR PORE COMPLEX PROTEIN NUP205 NUCLEAR PORE COMPLEX PROTEIN NUP205 CIOIN|Ensembl=ENSCING00000010522.3|UniProtKB=F6S2C6 F6S2C6 LOC100176316 PTHR11620:SF2 60S RIBOSOMAL PROTEIN L23A 60S RIBOSOMAL PROTEIN L23A structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;cellular process#GO:0009987;ribosomal large subunit biogenesis#GO:0042273;organelle assembly#GO:0070925;protein-RNA complex assembly#GO:0022618;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;organelle organization#GO:0006996;ribosomal large subunit assembly#GO:0000027;ribonucleoprotein complex biogenesis#GO:0022613;protein-RNA complex organization#GO:0071826;ribosome biogenesis#GO:0042254;non-membrane-bounded organelle assembly#GO:0140694 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic large ribosomal subunit#GO:0022625;large ribosomal subunit#GO:0015934;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000005301.3|UniProtKB=F6RUS9 F6RUS9 PTHR24114:SF49 LEUCINE RICH REPEAT FAMILY PROTEIN LEUCINE-RICH REPEAT-CONTAINING PROTEIN 74A CIOIN|Ensembl=ENSCING00000000383.3|UniProtKB=F6SF16 F6SF16 LOC100186930 PTHR11654:SF509 OLIGOPEPTIDE TRANSPORTER-RELATED SOLUTE CARRIER FAMILY 15 MEMBER 4 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 localization#GO:0051179;establishment of localization#GO:0051234;cellular process#GO:0009987;transmembrane transport#GO:0055085;transport#GO:0006810 cellular anatomical entity#GO:0110165;membrane#GO:0016020 transporter#PC00227 CIOIN|Ensembl=ENSCING00000002431.3|UniProtKB=F6QHD2 F6QHD2 PTHR21705:SF11 RAI16 PROTEIN-RELATED FHIP FAMILY PROTEIN CG3558 CIOIN|Ensembl=ENSCING00000005258.3|UniProtKB=F6V8V5 F6V8V5 LOC100186909 PTHR47966:SF51 BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;aspartic-type endopeptidase activity#GO:0004190;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 aspartic protease#PC00053;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000003222.3|UniProtKB=F7BBJ6 F7BBJ6 PTHR14091:SF0 PERIODIC TRYPTOPHAN PROTEIN 1 PERIODIC TRYPTOPHAN PROTEIN 1 HOMOLOG membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 CIOIN|Ensembl=ENSCING00000012914.2|UniProtKB=F6RMZ6 F6RMZ6 PTHR13651:SF0 PROTEIN ABITRAM PROTEIN ABITRAM CIOIN|Ensembl=ENSCING00000022354.1|UniProtKB=H2XVV8 H2XVV8 PTHR22826:SF106 RHO GUANINE EXCHANGE FACTOR-RELATED TRIO, ISOFORM A nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;guanyl-nucleotide exchange factor activity#GO:0005085 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;extrinsic component of membrane#GO:0019898 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 CIOIN|Ensembl=ENSCING00000022947.1|UniProtKB=H2Y152 H2Y152 LOC100184042 PTHR23271:SF1 HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN 66 U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 6 HOMOLOG snoRNA binding#GO:0030515;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;maturation of SSU-rRNA#GO:0030490;ribosomal small subunit biogenesis#GO:0042274;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;small-subunit processome#GO:0032040;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;nuclear lumen#GO:0031981;90S preribosome#GO:0030686;nuclear protein-containing complex#GO:0140513 RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000021478.1|UniProtKB=H2XSX9 H2XSX9 PTHR23115:SF301 TRANSLATION FACTOR ELONGATION FACTOR 1-ALPHA GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;nucleic acid binding#GO:0003676;translation regulator activity#GO:0045182;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;translation regulator activity, nucleic acid binding#GO:0090079;translation elongation factor activity#GO:0003746;translation factor activity, RNA binding#GO:0008135 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;translational elongation#GO:0006414;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 translation factor#PC00223;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000007497.3|UniProtKB=F6X7T3 F6X7T3 LOC100183879 PTHR11958:SF63 SODIUM/DICARBOXYLATE SYMPORTER-RELATED AMINO ACID TRANSPORTER primary active transporter#PC00068;transporter#PC00227 Ionotropic glutamate receptor pathway#P00037>EAAT#P01011;Metabotropic glutamate receptor group III pathway#P00039>EAAT#P01036 CIOIN|Ensembl=ENSCING00000021553.1|UniProtKB=H2Y0S2 H2Y0S2 PTHR11347:SF228 CYCLIC NUCLEOTIDE PHOSPHODIESTERASE HIGH AFFINITY CGMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 9A hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;cyclic-nucleotide phosphodiesterase activity#GO:0004112;phosphoric diester hydrolase activity#GO:0008081;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;cellular process#GO:0009987;cAMP-mediated signaling#GO:0019933;signaling#GO:0023052;cyclic-nucleotide-mediated signaling#GO:0019935 phosphodiesterase#PC00185 CIOIN|Ensembl=ENSCING00000006140.3|UniProtKB=F6V3N9 F6V3N9 LOC100183724 PTHR14002:SF54 ENDOGLIN/TGF-BETA RECEPTOR TYPE III ZONA PELLUCIDA SPERM-BINDING PROTEIN 2 transmembrane signal receptor#PC00197 CIOIN|Ensembl=ENSCING00000005369.3|UniProtKB=F7AWF9 F7AWF9 PTHR45836:SF4 SLIT HOMOLOG PROTEIN SLIT neuron projection guidance#GO:0097485;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;cell projection organization#GO:0030030;multicellular organism development#GO:0007275;developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;cellular process#GO:0009987;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cellular anatomical entity morphogenesis#GO:0032989;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;cell differentiation#GO:0030154;system development#GO:0048731;neuron projection development#GO:0031175;axon development#GO:0061564;cell morphogenesis involved in neuron differentiation#GO:0048667;axon guidance#GO:0007411;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;neuron differentiation#GO:0030182;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;axonogenesis#GO:0007409;plasma membrane bounded cell projection morphogenesis#GO:0120039;generation of neurons#GO:0048699 CIOIN|Ensembl=ENSCING00000002894.3|UniProtKB=F6SZU9 F6SZU9 PTHR19143:SF394 FIBRINOGEN/TENASCIN/ANGIOPOEITIN ANGIOPOIETIN-RELATED PROTEIN 3-LIKE external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 CIOIN|Ensembl=ENSCING00000024452.1|UniProtKB=H2XLY6 H2XLY6 dsba PTHR13887:SF41 GLUTATHIONE S-TRANSFERASE KAPPA THIOREDOXIN SUPERFAMILY PROTEIN transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000008655.3|UniProtKB=F6ZY58 F6ZY58 PTHR31826:SF0 NICALIN NICALIN biological regulation#GO:0065007;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;regulation of signaling#GO:0023051 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000021817.1|UniProtKB=H2XJX3 H2XJX3 LOC100176567 PTHR46536:SF3 ARL14 EFFECTOR PROTEIN ARF7 EFFECTOR PROTEIN C-TERMINAL DOMAIN-CONTAINING PROTEIN membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000020563.1|UniProtKB=H2Y1H2 H2Y1H2 PTHR10704:SF71 CARBOHYDRATE SULFOTRANSFERASE CARBOHYDRATE SULFOTRANSFERASE 1-LIKE sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824 cellular metabolic process#GO:0044237;amino sugar metabolic process#GO:0006040;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000012146.2|UniProtKB=F6W2L5 F6W2L5 LOC100181820 PTHR42796:SF4 FUMARYLACETOACETATE HYDROLASE DOMAIN-CONTAINING PROTEIN 2A-RELATED FUMARYLACETOACETATE HYDROLASE DOMAIN-CONTAINING PROTEIN 2A metabolite interconversion enzyme#PC00262;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000007911.3|UniProtKB=A0A1W5BB42 A0A1W5BB42 LOC100175113 PTHR24072:SF100 RHO FAMILY GTPASE RHO-RELATED GTP-BINDING PROTEIN RHOC GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;enzyme binding#GO:0019899;ribonucleoside triphosphate phosphatase activity#GO:0017111;kinase binding#GO:0019900;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;protein kinase binding#GO:0019901;anion binding#GO:0043168;ion binding#GO:0043167 regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;regulation of cellular process#GO:0050794;regulation of organelle organization#GO:0033043;regulation of actin cytoskeleton organization#GO:0032956;biological regulation#GO:0065007;regulation of actin filament-based process#GO:0032970;regulation of cellular component organization#GO:0051128 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 small GTPase#PC00208 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Rho#P00860;Axon guidance mediated by semaphorins#P00007>Rho#P00341;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>RhoA#P05938;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>RhoA#P00740;Ras Pathway#P04393>Rho#P04578;Integrin signalling pathway#P00034>Rho#P00948;Angiogenesis#P00005>GTPase#P00254;Axon guidance mediated by Slit/Robo#P00008>Rho#P00355;Cytoskeletal regulation by Rho GTPase#P00016>Rho#P00507 CIOIN|Ensembl=ENSCING00000001924.3|UniProtKB=F6ZIP1 F6ZIP1 zf(dhhc)-4 PTHR24161:SF85 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED PALMITOYLTRANSFERASE HIP14 protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000011337.2|UniProtKB=F6UXU4 F6UXU4 PTHR21404:SF3 HEN1 SMALL RNA 2'-O-METHYLTRANSFERASE CIOIN|Ensembl=ENSCING00000024428.1|UniProtKB=H2XV91 H2XV91 PTHR10983:SF73 1-ACYLGLYCEROL-3-PHOSPHATE ACYLTRANSFERASE-RELATED 1-ACYL-SN-GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE EPSILON transferase activity#GO:0016740;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;glycerolipid metabolic process#GO:0046486;cellular metabolic process#GO:0044237;phosphatidylinositol metabolic process#GO:0046488;organophosphate metabolic process#GO:0019637;glycerophospholipid metabolic process#GO:0006650;cellular process#GO:0009987;phospholipid metabolic process#GO:0006644;cellular lipid metabolic process#GO:0044255;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 acyltransferase#PC00042 CIOIN|Ensembl=ENSCING00000007068.3|UniProtKB=F6WW79 F6WW79 LOC100187208 PTHR12419:SF4 OTU DOMAIN CONTAINING PROTEIN OTU DOMAIN-CONTAINING PROTEIN 5 cysteine-type peptidase activity#GO:0008234;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;cysteine-type deubiquitinase activity#GO:0004843 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;protein modification by small protein removal#GO:0070646;protein deubiquitination#GO:0016579;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cysteine protease#PC00081;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000007230.3|UniProtKB=F6VKX9 F6VKX9 PTHR16007:SF15 EPIDIDYMAL MEMBRANE PROTEIN E9-RELATED TRANSMEMBRANE PROTEIN 45B CIOIN|Ensembl=ENSCING00000023477.1|UniProtKB=H2XZH9 H2XZH9 LOC100184454 PTHR23320:SF165 MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MS4A -RELATED MARVEL DOMAIN-CONTAINING PROTEIN transporter#PC00227 CIOIN|Ensembl=ENSCING00000005561.3|UniProtKB=F6USW1 F6USW1 PTHR19229:SF250 ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA ABC TRANSPORTER DOMAIN-CONTAINING PROTEIN-RELATED transmembrane transporter activity#GO:0022857;primary active transmembrane transporter activity#GO:0015399;ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657;transporter activity#GO:0005215;lipid transporter activity#GO:0005319;active transmembrane transporter activity#GO:0022804 localization#GO:0051179;organic substance transport#GO:0071702;lipid localization#GO:0010876;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;lipid transport#GO:0006869;transport#GO:0006810 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ATP-binding cassette (ABC) transporter#PC00003;transporter#PC00227 CIOIN|Ensembl=ENSCING00000008917.3|UniProtKB=F6QAR2 F6QAR2 PTHR31497:SF0 AUTOCRINE PROLIFERATION REPRESSOR PROTEIN A AUTOCRINE PROLIFERATION REPRESSOR PROTEIN A CIOIN|Ensembl=ENSCING00000015096.2|UniProtKB=F6XI97 F6XI97 LOC100178456 PTHR15852:SF54 PLASTID TRANSCRIPTIONALLY ACTIVE PROTEIN PROTEIN SSUH2 HOMOLOG CIOIN|Ensembl=ENSCING00000023354.1|UniProtKB=H2XJX4 H2XJX4 LOC100181596 PTHR12612:SF0 NUCLEAR TRANSPORT FACTOR 2 NUCLEAR TRANSPORT FACTOR 2 localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;transport#GO:0006810;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;cellular process#GO:0009987;nuclear transport#GO:0051169 envelope#GO:0031975;nuclear pore#GO:0005643;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear envelope#GO:0005635;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000004367.3|UniProtKB=F7AMZ2 F7AMZ2 LOC100179887 PTHR11610:SF173 LIPASE LIPASE DOMAIN-CONTAINING PROTEIN-RELATED hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;lipid catabolic process#GO:0016042;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;primary metabolic process#GO:0044238 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 lipase#PC00143;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000011597.2|UniProtKB=F6S1D4 F6S1D4 PTHR19302:SF13 GAMMA TUBULIN COMPLEX PROTEIN GAMMA-TUBULIN COMPLEX COMPONENT 2 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;meiotic cell cycle#GO:0051321;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;cellular process#GO:0009987;microtubule polymerization or depolymerization#GO:0031109;chromosome segregation#GO:0007059;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;reproduction#GO:0000003;microtubule polymerization#GO:0046785;microtubule-based process#GO:0007017;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;supramolecular fiber organization#GO:0097435;sexual reproduction#GO:0019953;protein polymerization#GO:0051258;spindle assembly#GO:0051225;reproductive process#GO:0022414;cell cycle#GO:0007049;cytoskeleton organization#GO:0007010;spindle organization#GO:0007051;non-membrane-bounded organelle assembly#GO:0140694;microtubule nucleation#GO:0007020;cytoplasmic microtubule organization#GO:0031122 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 CIOIN|Ensembl=ENSCING00000018542.1|UniProtKB=H2XTM7 H2XTM7 PTHR23176:SF129 RHO/RAC/CDC GTPASE-ACTIVATING PROTEIN RHO GTPASE ACTIVATING PROTEIN AT 16F, ISOFORM E-RELATED biological regulation#GO:0065007;regulation of hydrolase activity#GO:0051336;regulation of catalytic activity#GO:0050790;regulation of molecular function#GO:0065009;regulation of GTPase activity#GO:0043087 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 G-protein modulator#PC00022;protein-binding activity modulator#PC00095;GTPase-activating protein#PC00257 PDGF signaling pathway#P00047>Rho#P01174 CIOIN|Ensembl=ENSCING00000015337.2|UniProtKB=F6QDQ8 F6QDQ8 PTHR23503:SF8 SOLUTE CARRIER FAMILY 2 FACILITATED GLUCOSE TRANSPORTER PROTEIN 1 transmembrane transporter activity#GO:0022857;sugar transmembrane transporter activity#GO:0051119;transporter activity#GO:0005215;carbohydrate transmembrane transporter activity#GO:0015144 localization#GO:0051179;organic substance transport#GO:0071702;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810;cellular process#GO:0009987;carbohydrate transmembrane transport#GO:0034219;carbohydrate transport#GO:0008643 cellular anatomical entity#GO:0110165;membrane#GO:0016020 secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000000636.3|UniProtKB=F6RQT3 F6RQT3 PTHR24264:SF54 TRYPSIN-RELATED PEPTIDASE S1 DOMAIN-CONTAINING PROTEIN hydrolase activity#GO:0016787;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 serine protease#PC00203;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000004439.3|UniProtKB=F6XF88 F6XF88 LOC100183566 PTHR11071:SF561 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE D-RELATED peptidyl-prolyl cis-trans isomerase activity#GO:0003755;isomerase activity#GO:0016853;catalytic activity, acting on a protein#GO:0140096;binding#GO:0005488;catalytic activity#GO:0003824;peptide binding#GO:0042277;amide binding#GO:0033218 macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein peptidyl-prolyl isomerization#GO:0000413;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein folding#GO:0006457;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 chaperone#PC00072 CIOIN|Ensembl=ENSCING00000016742.2|UniProtKB=F6QZQ8 F6QZQ8 LOC100179749 PTHR33802:SF1 SI:CH211-161H7.5-RELATED XK-RELATED PROTEIN CIOIN|Ensembl=ENSCING00000012495.2|UniProtKB=F6U5C3 F6U5C3 PTHR11961:SF38 CYTOCHROME C CYTOCHROME C ISO-1_ISO-2 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0043280;positive regulation of cysteine-type endopeptidase activity#GO:2001056;regulation of protein metabolic process#GO:0051246;regulation of cysteine-type endopeptidase activity#GO:2000116;regulation of nitrogen compound metabolic process#GO:0051171;aerobic electron transport chain#GO:0019646;positive regulation of molecular function#GO:0044093;electron transport chain#GO:0022900;ATP synthesis coupled electron transport#GO:0042773;regulation of catalytic activity#GO:0050790;positive regulation of proteolysis#GO:0045862;energy derivation by oxidation of organic compounds#GO:0015980;regulation of biological process#GO:0050789;positive regulation of metabolic process#GO:0009893;regulation of molecular function#GO:0065009;respiratory electron transport chain#GO:0022904;regulation of hydrolase activity#GO:0051336;positive regulation of peptidase activity#GO:0010952;positive regulation of biological process#GO:0048518;mitochondrial electron transport, cytochrome c to oxygen#GO:0006123;metabolic process#GO:0008152;aerobic respiration#GO:0009060;regulation of proteolysis#GO:0030162;cellular respiration#GO:0045333;positive regulation of catalytic activity#GO:0043085;generation of precursor metabolites and energy#GO:0006091;cellular metabolic process#GO:0044237;mitochondrial electron transport, ubiquinol to cytochrome c#GO:0006122;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of hydrolase activity#GO:0051345;regulation of primary metabolic process#GO:0080090;mitochondrial ATP synthesis coupled electron transport#GO:0042775;positive regulation of protein metabolic process#GO:0051247;regulation of macromolecule metabolic process#GO:0060255;oxidative phosphorylation#GO:0006119;biological regulation#GO:0065007;regulation of endopeptidase activity#GO:0052548;regulation of peptidase activity#GO:0052547;regulation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0043281;positive regulation of endopeptidase activity#GO:0010950;regulation of metabolic process#GO:0019222 envelope#GO:0031975;membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;mitochondrial envelope#GO:0005740;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;mitochondrial intermembrane space#GO:0005758;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000010056.3|UniProtKB=F6QH11 F6QH11 PTHR12137:SF33 CARBOHYDRATE SULFOTRANSFERASE CARBOHYDRATE SULFOTRANSFERASE 14 sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824 transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000005762.2|UniProtKB=F6PU23 F6PU23 LOC100180664 PTHR13198:SF4 RING FINGER PROTEIN 25 E3 UBIQUITIN-PROTEIN LIGASE RNF25 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000009064.3|UniProtKB=F6R222 F6R222 PTHR24039:SF58 FIBRILLIN-RELATED EGF-LIKE DOMAIN-CONTAINING PROTEIN extracellular matrix structural protein#PC00103 CIOIN|Ensembl=ENSCING00000004821.3|UniProtKB=F6R982 F6R982 PTHR13211:SF0 TELOMERASE CAJAL BODY PROTEIN 1 TELOMERASE CAJAL BODY PROTEIN 1 CIOIN|Ensembl=ENSCING00000014148.2|UniProtKB=F7ARL3 F7ARL3 PTHR21290:SF27 SPHINGOMYELIN SYNTHETASE PHOSPHATIDYLCHOLINE:CERAMIDE CHOLINEPHOSPHOTRANSFERASE 1 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;phospholipid biosynthetic process#GO:0008654;organophosphate biosynthetic process#GO:0090407;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;membrane lipid biosynthetic process#GO:0046467;sphingolipid metabolic process#GO:0006665;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;ceramide metabolic process#GO:0006672;phosphate-containing compound metabolic process#GO:0006796;amide biosynthetic process#GO:0043604;membrane lipid metabolic process#GO:0006643;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;ceramide biosynthetic process#GO:0046513;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;amide metabolic process#GO:0043603;sphingolipid biosynthetic process#GO:0030148;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;Golgi membrane#GO:0000139;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 CIOIN|Ensembl=ENSCING00000022276.1|UniProtKB=H2XNJ5 H2XNJ5 PTHR13361:SF1 WW DOMAIN-BINDING PROTEIN 11 WW DOMAIN-BINDING PROTEIN 11 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000000437.3|UniProtKB=F7BJZ5 F7BJZ5 PTHR11705:SF17 PROTEASE FAMILY M14 CARBOXYPEPTIDASE A,B CARBOXYPEPTIDASE B2 metalloexopeptidase activity#GO:0008235;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;metallocarboxypeptidase activity#GO:0004181;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;carboxypeptidase activity#GO:0004180 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 metalloprotease#PC00153;protease#PC00190 Plasminogen activating cascade#P00050>TAFI#P01247 CIOIN|Ensembl=ENSCING00000016446.2|UniProtKB=F7BC02 F7BC02 LOC100175643 PTHR46738:SF1 UBIQUITIN-ASSOCIATED DOMAIN-CONTAINING PROTEIN 1 UBIQUITIN-ASSOCIATED DOMAIN-CONTAINING PROTEIN 1 intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;transferase complex#GO:1990234 CIOIN|Ensembl=ENSCING00000004306.3|UniProtKB=F6TSN4 F6TSN4 PTHR14166:SF17 SLIT-ROBO RHO GTPASE ACTIVATING PROTEIN RHO-GAP DOMAIN-CONTAINING PROTEIN GTPase-activating protein#PC00257 PDGF signaling pathway#P00047>Rho#P01174 CIOIN|Ensembl=ENSCING00000000087.3|UniProtKB=F6TS32 F6TS32 PTHR10005:SF25 SKI ONCOGENE-RELATED SNO ONCOGENE, ISOFORM B cis-regulatory region sequence-specific DNA binding#GO:0000987;SMAD binding#GO:0046332;transcription regulatory region nucleic acid binding#GO:0001067;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;protein binding#GO:0005515;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;negative regulation of response to stimulus#GO:0048585;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;regulation of BMP signaling pathway#GO:0030510;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;negative regulation of BMP signaling pathway#GO:0030514;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cellular response to growth factor stimulus#GO:0090287;negative regulation of signal transduction#GO:0009968;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000008245.3|UniProtKB=F6QZM4 F6QZM4 LOC100177981 PTHR24067:SF157 UBIQUITIN-CONJUGATING ENZYME E2 FI11905P ubiquitin-like protein conjugating enzyme activity#GO:0061650;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin conjugating enzyme activity#GO:0061631;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;protein polyubiquitination#GO:0000209;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000022712.1|UniProtKB=H2XY20 H2XY20 LOC100184495 PTHR11715:SF3 GLYCINE CLEAVAGE SYSTEM H PROTEIN GLYCINE CLEAVAGE SYSTEM H PROTEIN-RELATED macromolecule modification#GO:0043412;protein modification process#GO:0036211;gene expression#GO:0010467;organonitrogen compound catabolic process#GO:1901565;peptidyl-amino acid modification#GO:0018193;biosynthetic process#GO:0009058;amino acid catabolic process#GO:0009063;nitrogen compound metabolic process#GO:0006807;alpha-amino acid metabolic process#GO:1901605;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;protein metabolic process#GO:0019538;L-amino acid metabolic process#GO:0170033;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;oxoacid metabolic process#GO:0043436;proteinogenic amino acid metabolic process#GO:0170039;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein maturation#GO:0051604;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;carboxylic acid metabolic process#GO:0019752;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000005240.3|UniProtKB=F6XVH7 F6XVH7 PTHR43226:SF4 XAA-PRO AMINOPEPTIDASE 3 XAA-PRO AMINOPEPTIDASE 3 hydrolase activity#GO:0016787;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;metabolic process#GO:0008152;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704 metalloprotease#PC00153;protease#PC00190 CIOIN|Ensembl=ENSCING00000023687.1|UniProtKB=H2Y1G5 H2Y1G5 PTHR11254:SF363 HECT DOMAIN UBIQUITIN-PROTEIN LIGASE E3 UBIQUITIN-PROTEIN LIGASE HACE1 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 macromolecule modification#GO:0043412;membrane organization#GO:0061024;protein catabolic process#GO:0030163;endomembrane system organization#GO:0010256;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;post-translational protein modification#GO:0043687;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein polyubiquitination#GO:0000209;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;protein ubiquitination#GO:0016567;modification-dependent protein catabolic process#GO:0019941;macromolecule catabolic process#GO:0009057;protein modification by small protein conjugation or removal#GO:0070647;Golgi organization#GO:0007030;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular component organization#GO:0016043;cellular process#GO:0009987;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;membrane fusion#GO:0061025;organelle organization#GO:0006996 bounding membrane of organelle#GO:0098588;cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;Golgi membrane#GO:0000139;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234 CIOIN|Ensembl=ENSCING00000014510.2|UniProtKB=F6VP33 F6VP33 LOC100183210 PTHR13329:SF2 MITOCHONDRIAL RIBOSOMAL PROTEIN S18B SMALL RIBOSOMAL SUBUNIT PROTEIN MS40 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000012960.2|UniProtKB=F6RBS2 F6RBS2 PTHR44942:SF4 METHYLTRANSF_11 DOMAIN-CONTAINING PROTEIN METHYLTRANSFERASE TYPE 11 DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000006939.3|UniProtKB=F6VN41 F6VN41 LOC100182501 PTHR12558:SF10 CELL DIVISION CYCLE 16,23,27 CELL DIVISION CYCLE PROTEIN 23 HOMOLOG cell division#GO:0051301;regulation of mitotic nuclear division#GO:0007088;regulation of chromosome segregation#GO:0051983;positive regulation of organelle organization#GO:0010638;macromolecule modification#GO:0043412;regulation of chromosome separation#GO:1905818;protein catabolic process#GO:0030163;organonitrogen compound catabolic process#GO:1901565;protein modification process#GO:0036211;regulation of cellular component organization#GO:0051128;positive regulation of cell cycle#GO:0045787;post-translational protein modification#GO:0043687;modification-dependent macromolecule catabolic process#GO:0043632;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;positive regulation of cell cycle process#GO:0090068;positive regulation of mitotic cell cycle#GO:0045931;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;positive regulation of biological process#GO:0048518;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of chromosome organization#GO:0033044;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;regulation of mitotic sister chromatid separation#GO:0010965;regulation of nuclear division#GO:0051783;protein modification by small protein conjugation or removal#GO:0070647;regulation of mitotic cell cycle phase transition#GO:1901990;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;regulation of organelle organization#GO:0033043;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;positive regulation of mitotic nuclear division#GO:0045840;regulation of cell cycle phase transition#GO:1901987;organonitrogen compound metabolic process#GO:1901564;cellular process#GO:0009987;regulation of mitotic metaphase/anaphase transition#GO:0030071;primary metabolic process#GO:0044238;regulation of cell cycle process#GO:0010564;positive regulation of cellular process#GO:0048522;ubiquitin-dependent protein catabolic process#GO:0006511;anaphase-promoting complex-dependent catabolic process#GO:0031145;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;regulation of cell cycle#GO:0051726;regulation of sister chromatid segregation#GO:0033045;regulation of mitotic cell cycle#GO:0007346 ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;cullin-RING ubiquitin ligase complex#GO:0031461;transferase complex#GO:1990234;anaphase-promoting complex#GO:0005680;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;nuclear ubiquitin ligase complex#GO:0000152;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000006398.3|UniProtKB=F6RF58 F6RF58 LOC100179482 PTHR31516:SF17 STABILIZER OF AXONEMAL MICROTUBULES 2 STABILIZER OF AXONEMAL MICROTUBULES 2 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;microtubule binding#GO:0008017;tubulin binding#GO:0015631;binding#GO:0005488 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 CIOIN|Ensembl=ENSCING00000020718.1|UniProtKB=H2XWA7 H2XWA7 PTHR23322:SF28 FAS-ASSOCIATED PROTEIN UBX DOMAIN-CONTAINING PROTEIN 10 protein binding#GO:0005515;ubiquitin-like protein binding#GO:0032182;binding#GO:0005488;ubiquitin binding#GO:0043130 response to organic substance#GO:0010033;macromolecule catabolic process#GO:0009057;cellular response to stimulus#GO:0051716;response to endoplasmic reticulum stress#GO:0034976;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;response to organonitrogen compound#GO:0010243;ERAD pathway#GO:0036503;cellular process#GO:0009987;primary metabolic process#GO:0044238;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;cellular response to stress#GO:0033554;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000002344.3|UniProtKB=F6PJV8 F6PJV8 LOC100176571 PTHR24068:SF147 UBIQUITIN-CONJUGATING ENZYME E2 E2 UBIQUITIN-CONJUGATING ENZYME ubiquitin-like protein conjugating enzyme activity#GO:0061650;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin conjugating enzyme activity#GO:0061631;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein polyubiquitination#GO:0000209;post-translational protein modification#GO:0043687;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 Ubiquitin proteasome pathway#P00060>E3#P01490;Ubiquitin proteasome pathway#P00060>E2#P01491 CIOIN|Ensembl=ENSCING00000011926.2|UniProtKB=F6W7J8 F6W7J8 PTHR10209:SF881 OXIDOREDUCTASE, 2OG-FE II OXYGENASE FAMILY PROTEIN FI07970P-RELATED oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000007447.3|UniProtKB=F7ANP5 F7ANP5 PTHR45237:SF2 POSSIBLE PARA-NITROBENZYL ESTERASE POSSIBLE PARA-NITROBENZYL ESTERASE esterase#PC00097 CIOIN|Ensembl=ENSCING00000018269.1|UniProtKB=F6UAD5 F6UAD5 PTHR10963:SF55 GLYCOSYL HYDROLASE-RELATED GLYCOSIDE HYDROLASE FAMILY 16 PROTEIN glucosidase#PC00108;metabolite interconversion enzyme#PC00262;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000018073.1|UniProtKB=H2XQW2 H2XQW2 PTHR31395:SF23 SHISA GEO05642P1 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000006771.3|UniProtKB=F6VEU9 F6VEU9 LOC100175300 PTHR10529:SF262 AP COMPLEX SUBUNIT MU ADAPTOR PROTEIN COMPLEX 1, MU SUBUNIT localization#GO:0051179;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization#GO:0051234;transport#GO:0006810 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150 CIOIN|Ensembl=ENSCING00000012998.2|UniProtKB=F6V7C2 F6V7C2 PTHR24418:SF448 TYROSINE-PROTEIN KINASE INACTIVE TYROSINE-PROTEIN KINASE WSCK-RELATED protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 non-receptor tyrosine protein kinase#PC00168 CIOIN|Ensembl=ENSCING00000022740.1|UniProtKB=H2XK68 H2XK68 PTHR34231:SF6 EXS-RELATED PROTEIN AGAP006868-PA CIOIN|Ensembl=ENSCING00000021419.1|UniProtKB=H2XP91 H2XP91 LOC100178512 PTHR12990:SF5 ARMET-LIKE PROTEIN MESENCEPHALIC ASTROCYTE-DERIVED NEUROTROPHIC FACTOR HOMOLOG CIOIN|Ensembl=ENSCING00000017347.2|UniProtKB=F6XPD3 F6XPD3 PTHR20338:SF8 NUCLEAR RESPIRATORY FACTOR 1 NUCLEAR RESPIRATORY FACTOR 1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218 CIOIN|Ensembl=ENSCING00000018177.1|UniProtKB=H2XRT9 H2XRT9 PTHR42693:SF15 ARYLSULFATASE FAMILY MEMBER ARYLSULFATASE hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000006895.3|UniProtKB=F6YAM0 F6YAM0 PTHR46618:SF1 ARMADILLO REPEAT-CONTAINING PROTEIN 3 ARMADILLO REPEAT-CONTAINING PROTEIN 3 CIOIN|Ensembl=ENSCING00000009356.3|UniProtKB=F6XKY1 F6XKY1 PTHR42908:SF10 TRANSLATION ELONGATION FACTOR-RELATED EUKARYOTIC TRANSLATION ELONGATION FACTOR 2 GTPase activity#GO:0003924;nucleic acid binding#GO:0003676;binding#GO:0005488;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;translation regulator activity#GO:0045182;organic cyclic compound binding#GO:0097159;ribonucleoprotein complex binding#GO:0043021;hydrolase activity#GO:0016787;ribosome binding#GO:0043022;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;protein-containing complex binding#GO:0044877;translation regulator activity, nucleic acid binding#GO:0090079;translation elongation factor activity#GO:0003746;translation factor activity, RNA binding#GO:0008135 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;translational elongation#GO:0006414;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622 translation elongation factor#PC00222 CIOIN|Ensembl=ENSCING00000003111.3|UniProtKB=F6RD62 F6RD62 PTHR10218:SF360 GTP-BINDING PROTEIN ALPHA SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN SUBUNIT ALPHA HOMOLOG GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;ribonucleoside triphosphate phosphatase activity#GO:0017111;G protein-coupled receptor binding#GO:0001664;signaling receptor binding#GO:0005102 regulation of biological process#GO:0050789;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cytoplasm#GO:0005737;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;cytoplasmic side of plasma membrane#GO:0009898;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622;extrinsic component of membrane#GO:0019898 heterotrimeric G-protein#PC00117;G-protein#PC00020 CIOIN|Ensembl=ENSCING00000004557.3|UniProtKB=F6XD08 F6XD08 PTHR24133:SF33 ANKYRIN DOMAIN-CONTAINING ANKYRIN, ISOFORM B cytoskeletal protein binding#GO:0008092;molecular adaptor activity#GO:0060090;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;transmembrane transporter binding#GO:0044325;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674 localization#GO:0051179;protein localization to plasma membrane#GO:0072659;protein localization to cell periphery#GO:1990778;localization within membrane#GO:0051668;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;protein localization to membrane#GO:0072657;cellular process#GO:0009987;protein localization#GO:0008104 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;neuron projection#GO:0043005;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000004277.3|UniProtKB=F6UGD7 F6UGD7 PTHR11474:SF124 TYROSINASE FAMILY MEMBER TYROSINASE oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497 cellular aromatic compound metabolic process#GO:0006725;organic hydroxy compound metabolic process#GO:1901615;secondary metabolic process#GO:0019748;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;pigment metabolic process#GO:0042440;organic hydroxy compound biosynthetic process#GO:1901617;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;organic cyclic compound metabolic process#GO:1901360;secondary metabolite biosynthetic process#GO:0044550;pigment biosynthetic process#GO:0046148;aromatic compound biosynthetic process#GO:0019438;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 oxygenase#PC00177;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000023622.1|UniProtKB=H2XX71 H2XX71 PTHR24388:SF85 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 367 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 CIOIN|Ensembl=ENSCING00000002952.3|UniProtKB=F6R8C3 F6R8C3 PTHR15897:SF2 ANKYRIN REPEAT AND MYND DOMAIN PROTEIN 1 ANKYRIN REPEAT AND MYND DOMAIN-CONTAINING PROTEIN 1 CIOIN|Ensembl=ENSCING00000000385.3|UniProtKB=F6SF30 F6SF30 PTHR12979:SF5 CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 10 CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 10 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;regulation of amide metabolic process#GO:0034248;heterocycle catabolic process#GO:0046700;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;nucleobase-containing compound metabolic process#GO:0006139;cellular nitrogen compound catabolic process#GO:0044270;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;mRNA catabolic process#GO:0006402;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;organic substance catabolic process#GO:1901575;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;negative regulation of biosynthetic process#GO:0009890;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;negative regulation of translation#GO:0017148;aromatic compound catabolic process#GO:0019439;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;post-transcriptional regulation of gene expression#GO:0010608;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;regulation of translation#GO:0006417;nucleobase-containing compound catabolic process#GO:0034655;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 CCR4-NOT complex#GO:0030014;intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991 CIOIN|Ensembl=ENSCING00000022228.1|UniProtKB=H2XLB1 H2XLB1 PTHR48069:SF3 DIHYDROFOLATE REDUCTASE DIHYDROFOLATE REDUCTASE nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;oxidoreductase activity#GO:0016491 cellular aromatic compound metabolic process#GO:0006725;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;dicarboxylic acid metabolic process#GO:0043648;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;folic acid-containing compound metabolic process#GO:0006760;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;heterocycle biosynthetic process#GO:0018130;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;cellular modified amino acid metabolic process#GO:0006575;aromatic compound biosynthetic process#GO:0019438;carboxylic acid metabolic process#GO:0019752;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 reductase#PC00198;oxidoreductase#PC00176 Formyltetrahydrofolate biosynthesis#P02743>Dihydrofolate reductase#P02957;Tetrahydrofolate biosynthesis#P02742>Dihydrofolate reductase#P02948;Tetrahydrofolate biosynthesis#P02742>Dihydrofolate synthase#P02943 CIOIN|Ensembl=ENSCING00000003500.3|UniProtKB=F6TLJ7 F6TLJ7 PTHR10194:SF146 RAS GTPASE-ACTIVATING PROTEINS RAS GTPASE-ACTIVATING PROTEIN 1 G-protein modulator#PC00022;protein-binding activity modulator#PC00095;GTPase-activating protein#PC00257 Angiogenesis#P00005>RasGAP#P00190;Interleukin signaling pathway#P00036>RasGAP#P00975;EGF receptor signaling pathway#P00018>GAP#P00546;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>Ras#P00886;Angiogenesis#P00005>GAP#P00205;PDGF signaling pathway#P00047>RasGAP#P01152;FGF signaling pathway#P00021>RasGAP#P00646 CIOIN|Ensembl=ENSCING00000014774.2|UniProtKB=F6VMC6 F6VMC6 PTHR12561:SF3 LIPOATE-PROTEIN LIGASE LIPOYLTRANSFERASE 1, MITOCHONDRIAL transferase activity#GO:0016740;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity#GO:0003824 macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;peptidyl-amino acid modification#GO:0018193;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000021423.1|UniProtKB=H2Y3S3 H2Y3S3 LOC100175627 PTHR11954:SF6 D-DOPACHROME DECARBOXYLASE MACROPHAGE MIGRATION INHIBITORY FACTOR isomerase activity#GO:0016853;catalytic activity#GO:0003824 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 decarboxylase#PC00089;lyase#PC00144 CIOIN|Ensembl=ENSCING00000006837.3|UniProtKB=F7AZH2 F7AZH2 LOC100186591 PTHR13066:SF2 BASIC LEUCINE ZIPPER NUCLEAR FACTOR 1 BLZF1 PROTEIN GOLGIN-45 protein localization to plasma membrane#GO:0072659;localization within membrane#GO:0051668;cellular localization#GO:0051641;vesicle-mediated transport to the plasma membrane#GO:0098876;Golgi organization#GO:0007030;macromolecule localization#GO:0033036;protein localization to membrane#GO:0072657;post-Golgi vesicle-mediated transport#GO:0006892;transport#GO:0006810;endomembrane system organization#GO:0010256;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;establishment of protein localization#GO:0045184;Golgi to plasma membrane transport#GO:0006893;protein localization#GO:0008104;localization#GO:0051179;protein localization to cell periphery#GO:1990778;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;establishment of protein localization to membrane#GO:0090150;Golgi to plasma membrane protein transport#GO:0043001;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;organelle organization#GO:0006996;protein transport#GO:0015031 bounding membrane of organelle#GO:0098588;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;Golgi membrane#GO:0000139;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;basic leucine zipper transcription factor#PC00056 CIOIN|Ensembl=ENSCING00000005053.3|UniProtKB=F7A5H4 F7A5H4 LOC100186466 PTHR15146:SF3 INTEGRAL MEMBRANE PROTEIN GPR137 THH1_TOM1_TOM3 DOMAIN-CONTAINING PROTEIN regulation of cell communication#GO:0010646;positive regulation of TORC1 signaling#GO:1904263;regulation of TORC1 signaling#GO:1903432;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;regulation of TOR signaling#GO:0032006;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;regulation of cellular process#GO:0050794;positive regulation of TOR signaling#GO:0032008;regulation of signal transduction#GO:0009966;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518 bounding membrane of organelle#GO:0098588;lytic vacuole membrane#GO:0098852;intracellular membrane-bounded organelle#GO:0043231;vacuolar membrane#GO:0005774;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;lytic vacuole#GO:0000323;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;lysosomal membrane#GO:0005765;lysosome#GO:0005764;membrane-bounded organelle#GO:0043227 CIOIN|Ensembl=ENSCING00000019832.1|UniProtKB=H2XNW6 H2XNW6 LOC100182410 PTHR48069:SF3 DIHYDROFOLATE REDUCTASE DIHYDROFOLATE REDUCTASE nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;oxidoreductase activity#GO:0016491 cellular aromatic compound metabolic process#GO:0006725;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;dicarboxylic acid metabolic process#GO:0043648;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;folic acid-containing compound metabolic process#GO:0006760;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;heterocycle biosynthetic process#GO:0018130;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;cellular modified amino acid metabolic process#GO:0006575;aromatic compound biosynthetic process#GO:0019438;carboxylic acid metabolic process#GO:0019752;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 reductase#PC00198;oxidoreductase#PC00176 Formyltetrahydrofolate biosynthesis#P02743>Dihydrofolate reductase#P02957;Tetrahydrofolate biosynthesis#P02742>Dihydrofolate reductase#P02948;Tetrahydrofolate biosynthesis#P02742>Dihydrofolate synthase#P02943 CIOIN|Ensembl=ENSCING00000022473.1|UniProtKB=H2XLA2 H2XLA2 PTHR12651:SF1 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 9 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 9 protein-containing complex assembly#GO:0065003;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;cellular process#GO:0009987;protein-containing complex organization#GO:0043933 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protease#PC00190 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489 CIOIN|Ensembl=ENSCING00000013244.2|UniProtKB=F6SGF2 F6SGF2 ci-tlr2 PTHR24365:SF530 TOLL-LIKE RECEPTOR MSTPROX-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;response to stress#GO:0006950;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;defense response#GO:0006952;signaling#GO:0023052;inflammatory response#GO:0006954 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 CIOIN|Ensembl=ENSCING00000019530.1|UniProtKB=H2XYC4 H2XYC4 PTHR13502:SF6 CDC42 SMALL EFFECTOR PROTEIN HOMOLOG CDC42 SMALL EFFECTOR PROTEIN HOMOLOG cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 CIOIN|Ensembl=ENSCING00000003881.3|UniProtKB=A0A1W5BD87 A0A1W5BD87 LOC100178665 PTHR11863:SF226 STEROL DESATURASE FATTY ACID HYDROXYLASE DOMAIN-CONTAINING PROTEIN 2-RELATED oxidase#PC00175;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000009059.3|UniProtKB=F7BH52 F7BH52 PTHR23151:SF90 DIHYDROLIPOAMIDE ACETYL/SUCCINYL-TRANSFERASE-RELATED DIHYDROLIPOYLLYSINE-RESIDUE ACETYLTRANSFERASE COMPONENT OF PYRUVATE DEHYDROGENASE COMPLEX, MITOCHONDRIAL-RELATED transferase#PC00220;acetyltransferase#PC00038;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000013482.2|UniProtKB=F7BKJ3 F7BKJ3 LOC778705 PTHR12632:SF6 TRANSCRIPTION FACTOR NF-Y ALPHA-RELATED NUCLEAR TRANSCRIPTION FACTOR Y SUBUNIT ALPHA transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 DNA-binding transcription factor#PC00218 Gonadotropin-releasing hormone receptor pathway#P06664>NF-Y#P06742 CIOIN|Ensembl=ENSCING00000006280.3|UniProtKB=F6UBT3 F6UBT3 PTHR11851:SF149 METALLOPROTEASE GH01077P cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000005178.3|UniProtKB=Q4H2U4 Q4H2U4 Ci-sFRP2 PTHR11309:SF148 FRIZZLED SECRETED FRIZZLED-RELATED PROTEIN 1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;protein binding#GO:0005515;Wnt-protein binding#GO:0017147;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;non-canonical Wnt signaling pathway#GO:0035567;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;cell-cell signaling by wnt#GO:0198738;canonical Wnt signaling pathway#GO:0060070;cell-cell signaling#GO:0007267;signaling#GO:0023052;Wnt signaling pathway#GO:0016055 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;extracellular space#GO:0005615;membrane#GO:0016020;extracellular region#GO:0005576;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 CIOIN|Ensembl=ENSCING00000008090.3|UniProtKB=F6PM75 F6PM75 LOC100176470 PTHR12728:SF0 BRIX DOMAIN CONTAINING PROTEIN RIBOSOME PRODUCTION FACTOR 2 HOMOLOG nucleic acid binding#GO:0003676;RNA binding#GO:0003723;rRNA binding#GO:0019843;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;RNA processing#GO:0006396;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;biosynthetic process#GO:0009058;ribosomal large subunit biogenesis#GO:0042273;nucleobase-containing compound metabolic process#GO:0006139;protein-RNA complex assembly#GO:0022618;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;ribosomal large subunit assembly#GO:0000027;ribosome biogenesis#GO:0042254;non-membrane-bounded organelle assembly#GO:0140694;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular component organization#GO:0016043;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;protein-RNA complex organization#GO:0071826;maturation of LSU-rRNA#GO:0000470 intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000009010.3|UniProtKB=F6PHD5 F6PHD5 LOC100178933 PTHR11560:SF8 39S RIBOSOMAL PROTEIN L10, MITOCHONDRIAL LARGE RIBOSOMAL SUBUNIT PROTEIN UL10M structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;large ribosomal subunit#GO:0015934;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000014445.2|UniProtKB=F6YB67 F6YB67 PTHR12111:SF1 SPLICING FACTOR YJU2 SPLICING FACTOR YJU2 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;U2-type spliceosomal complex#GO:0005684;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA splicing factor#PC00148;RNA processing factor#PC00147;RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000020512.1|UniProtKB=H2Y060 H2Y060 PTHR11431:SF75 FERRITIN FERRITIN cation binding#GO:0043169;ferrous iron binding#GO:0008198;small molecule binding#GO:0036094;binding#GO:0005488;iron ion binding#GO:0005506;transition metal ion binding#GO:0046914;metal ion binding#GO:0046872;ion binding#GO:0043167 localization#GO:0051179;inorganic ion homeostasis#GO:0098771;cellular localization#GO:0051641;intracellular iron ion homeostasis#GO:0006879;maintenance of location#GO:0051235;maintenance of location in cell#GO:0051651;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;homeostatic process#GO:0042592;intracellular monoatomic ion homeostasis#GO:0006873;chemical homeostasis#GO:0048878;cellular process#GO:0009987;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;monoatomic ion homeostasis#GO:0050801 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 storage protein#PC00210 CIOIN|Ensembl=ENSCING00000015969.2|UniProtKB=F6SFM0 F6SFM0 LOC100184155 PTHR11009:SF32 DER1-LIKE PROTEIN, DERLIN DERLIN ribonucleoprotein complex binding#GO:0043021;protein-containing complex binding#GO:0044877;binding#GO:0005488 signal transduction#GO:0007165;endoplasmic reticulum unfolded protein response#GO:0030968;protein catabolic process#GO:0030163;organonitrogen compound catabolic process#GO:1901565;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;response to unfolded protein#GO:0006986;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;protein metabolic process#GO:0019538;signaling#GO:0023052;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;response to organic substance#GO:0010033;macromolecule catabolic process#GO:0009057;cellular response to stimulus#GO:0051716;response to endoplasmic reticulum stress#GO:0034976;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;ERAD pathway#GO:0036503;cell communication#GO:0007154;response to organonitrogen compound#GO:0010243;cellular process#GO:0009987;cellular response to topologically incorrect protein#GO:0035967;primary metabolic process#GO:0044238;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;response to topologically incorrect protein#GO:0035966;cellular response to unfolded protein#GO:0034620;biological regulation#GO:0065007;cellular response to stress#GO:0033554 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 primary active transporter#PC00068;transporter#PC00227 CIOIN|Ensembl=ENSCING00000018216.1|UniProtKB=H2XRG0 H2XRG0 PTHR19282:SF544 TETRASPANIN TETRASPANIN cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000021277.1|UniProtKB=F6R0H1 F6R0H1 PTHR14969:SF39 SPHINGOSINE-1-PHOSPHATE PHOSPHOHYDROLASE PHOSPHATIDIC ACID PHOSPHATASE TYPE 2_HALOPEROXIDASE DOMAIN-CONTAINING PROTEIN hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 organic hydroxy compound metabolic process#GO:1901615;lipid metabolic process#GO:0006629;membrane lipid metabolic process#GO:0006643;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;alcohol metabolic process#GO:0006066;cellular process#GO:0009987;cellular lipid metabolic process#GO:0044255;sphingolipid metabolic process#GO:0006665;primary metabolic process#GO:0044238;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;phosphatase#PC00181;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000023562.1|UniProtKB=H2XWM3 H2XWM3 PTHR24373:SF398 SLIT RELATED LEUCINE-RICH REPEAT NEURONAL PROTEIN LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 6 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 transmembrane signal receptor#PC00197 CIOIN|Ensembl=ENSCING00000006496.4|UniProtKB=F6RMR3 F6RMR3 PTHR18911:SF5 CTCL TUMOR ANTIGEN HD-CL-01 COILED-COIL DOMAIN-CONTAINING PROTEIN 186 CIOIN|Ensembl=ENSCING00000008884.3|UniProtKB=F7B221 F7B221 PTHR24210:SF0 LIM DOMAIN-CONTAINING PROTEIN LIM DOMAIN-CONTAINING PROTEIN cell junction protein#PC00070 Integrin signalling pathway#P00034>PINCH#P00921 CIOIN|Ensembl=ENSCING00000005726.3|UniProtKB=F6U2I3 F6U2I3 PTHR24409:SF295 ZINC FINGER PROTEIN 142 AZ2-RELATED sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 CIOIN|Ensembl=ENSCING00000013497.2|UniProtKB=F7B236 F7B236 PTHR24189:SF71 MYOTROPHIN ANKYRIN REPEAT DOMAIN 39 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000012577.2|UniProtKB=F6Y4F7 F6Y4F7 LOC100180912 PTHR12416:SF3 RRNA-PROCESSING PROTEIN UTP23 HOMOLOG RRNA-PROCESSING PROTEIN UTP23 HOMOLOG CIOIN|Ensembl=ENSCING00000001625.3|UniProtKB=F7B8I8 F7B8I8 PTHR11875:SF49 TESTIS-SPECIFIC Y-ENCODED PROTEIN PROTEIN SET protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;chromatin binding#GO:0003682;histone binding#GO:0042393 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-DNA complex#GO:0032993;chromosome#GO:0005694;chromatin#GO:0000785;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 CIOIN|Ensembl=ENSCING00000005092.3|UniProtKB=H2Y2W3 H2Y2W3 PTHR11214:SF219 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE UDP-GALNAC:BETA-1,3-N-ACETYLGALACTOSAMINYLTRANSFERASE 2 transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;protein O-linked glycosylation#GO:0006493;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 bounding membrane of organelle#GO:0098588;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;Golgi membrane#GO:0000139;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111 CIOIN|Ensembl=ENSCING00000013738.2|UniProtKB=F6RR57 F6RR57 PTHR22760:SF3 GLYCOSYLTRANSFERASE GPI MANNOSYLTRANSFERASE 4 mannosyltransferase activity#GO:0000030;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;phospholipid biosynthetic process#GO:0008654;macromolecule modification#GO:0043412;phosphatidylinositol biosynthetic process#GO:0006661;organophosphate biosynthetic process#GO:0090407;glycolipid metabolic process#GO:0006664;protein modification process#GO:0036211;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;lipid biosynthetic process#GO:0008610;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;protein lipidation#GO:0006497;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;glycerolipid biosynthetic process#GO:0045017;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;glycerophospholipid metabolic process#GO:0006650;phosphatidylinositol metabolic process#GO:0046488;organic substance biosynthetic process#GO:1901576;liposaccharide metabolic process#GO:1903509;cellular process#GO:0009987;membrane lipid biosynthetic process#GO:0046467;GPI anchor metabolic process#GO:0006505;lipoprotein biosynthetic process#GO:0042158;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;GPI anchor biosynthetic process#GO:0006506;membrane lipid metabolic process#GO:0006643;glycerophospholipid biosynthetic process#GO:0046474;glycolipid biosynthetic process#GO:0009247;organophosphate metabolic process#GO:0019637;lipoprotein metabolic process#GO:0042157;cellular lipid metabolic process#GO:0044255 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;endoplasmic reticulum membrane#GO:0005789 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000008467.3|UniProtKB=F6TQI0 F6TQI0 PTHR10010:SF46 SOLUTE CARRIER FAMILY 34 SODIUM PHOSPHATE , MEMBER 2-RELATED SODIUM-DEPENDENT PHOSPHATE TRANSPORT PROTEIN 2B secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000003216.3|UniProtKB=F6S2F9 F6S2F9 nachr PTHR18945:SF865 NEUROTRANSMITTER GATED ION CHANNEL NICOTINIC ACETYLCHOLINE RECEPTOR ALPHA7, ISOFORM E ligand-gated ion channel#PC00141;ion channel#PC00133;transporter#PC00227 CIOIN|Ensembl=ENSCING00000005364.3|UniProtKB=F7BF34 F7BF34 PTHR46004:SF3 CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN A CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN A sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 Transcription regulation by bZIP transcription factor#P00055>CREB#P01383;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>CREB#P00713 CIOIN|Ensembl=ENSCING00000004372.3|UniProtKB=F7AV11 F7AV11 PTHR23031:SF15 RHOPHILIN LD12055P negative regulation of biological process#GO:0048519;regulation of organelle organization#GO:0033043;regulation of actin filament organization#GO:0110053;regulation of cellular component organization#GO:0051128;negative regulation of supramolecular fiber organization#GO:1902904;regulation of supramolecular fiber organization#GO:1902903;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;regulation of stress fiber assembly#GO:0051492;regulation of cellular process#GO:0050794;regulation of cellular component biogenesis#GO:0044087;negative regulation of organelle organization#GO:0010639;biological regulation#GO:0065007;regulation of actin cytoskeleton organization#GO:0032956;regulation of actin filament-based process#GO:0032970;negative regulation of cellular component organization#GO:0051129;negative regulation of cytoskeleton organization#GO:0051494;regulation of actin filament bundle assembly#GO:0032231;negative regulation of cellular process#GO:0048523 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000005085.3|UniProtKB=F6Z2U1 F6Z2U1 PTHR47969:SF15 CHROMOSOME-ASSOCIATED KINESIN KIF4A-RELATED CHROMOSOME-ASSOCIATED KINESIN KIF4A-RELATED cytoskeletal motor activity#GO:0003774;microtubule motor activity#GO:0003777;ATP-dependent activity#GO:0140657 nuclear chromosome segregation#GO:0098813;mitotic spindle organization#GO:0007052;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;cellular component organization#GO:0016043;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cellular process#GO:0009987;spindle elongation#GO:0051231;mitotic cell cycle process#GO:1903047;chromosome segregation#GO:0007059;cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;microtubule-based process#GO:0007017;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;cell cycle#GO:0007049;spindle organization#GO:0007051 intracellular non-membrane-bounded organelle#GO:0043232;microtubule associated complex#GO:0005875;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 CIOIN|Ensembl=ENSCING00000007087.3|UniProtKB=F6W912 F6W912 PTHR48014:SF21 SERINE/THREONINE-PROTEIN KINASE FRAY2 SERINE_THREONINE-PROTEIN KINASE FRAY2 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Endothelin signaling pathway#P00019>PKA#P00570;Transcription regulation by bZIP transcription factor#P00055>PKA#P01384 CIOIN|Ensembl=ENSCING00000021605.1|UniProtKB=H2Y083 H2Y083 PTHR22802:SF457 C-TYPE LECTIN SUPERFAMILY MEMBER ASIALOGLYCOPROTEIN RECEPTOR-LIKE 1 membrane traffic protein#PC00150 CIOIN|Ensembl=ENSCING00000023230.1|UniProtKB=H2Y2S2 H2Y2S2 PTHR21347:SF14 CLEFT LIP AND PALATE ASSOCIATED TRANSMEMBRANE PROTEIN-RELATED LIPID SCRAMBLASE CLPTM1-RELATED cellular anatomical entity#GO:0110165;membrane#GO:0016020;endomembrane system#GO:0012505 CIOIN|Ensembl=ENSCING00000013019.2|UniProtKB=F6UGF1 F6UGF1 LOC100177537 PTHR24056:SF546 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE 12 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of transcription elongation by RNA polymerase II#GO:0034243;positive regulation of transcription elongation by RNA polymerase II#GO:0032968;positive regulation of RNA biosynthetic process#GO:1902680;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of transcription by RNA polymerase II#GO:0045944;protein modification process#GO:0036211;positive regulation of DNA-templated transcription, elongation#GO:0032786;regulation of RNA biosynthetic process#GO:2001141;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;phosphorylation#GO:0016310;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of DNA-templated transcription elongation#GO:0032784;regulation of DNA-templated transcription#GO:0006355;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;positive regulation of RNA metabolic process#GO:0051254;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cyclin-dependent protein kinase holoenzyme complex#GO:0000307;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;protein kinase complex#GO:1902911;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695 non-receptor serine/threonine protein kinase#PC00167 CIOIN|Ensembl=ENSCING00000017193.2|UniProtKB=F6T3M2 F6T3M2 PTHR13866:SF14 SPARC OSTEONECTIN BM-40 cation binding#GO:0043169;extracellular matrix binding#GO:0050840;small molecule binding#GO:0036094;binding#GO:0005488;collagen binding#GO:0005518;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;protein-containing complex binding#GO:0044877;ion binding#GO:0043167 anatomical structure development#GO:0048856;developmental process#GO:0032502 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 extracellular matrix glycoprotein#PC00100 CIOIN|Ensembl=ENSCING00000008735.3|UniProtKB=F6TMT5 F6TMT5 LOC100182334 PTHR24067:SF3 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 G1 ubiquitin-like protein conjugating enzyme activity#GO:0061650;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin conjugating enzyme activity#GO:0061631;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;protein polyubiquitination#GO:0000209;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 Ubiquitin proteasome pathway#P00060>E2#P01491 CIOIN|Ensembl=ENSCING00000022178.1|UniProtKB=H2Y2V5 H2Y2V5 PTHR14972:SF8 AGAP011572-PA GLUCOCORTICOID-INDUCED TRANSCRIPT 1 PROTEIN-LIKE ISOFORM X1 CIOIN|Ensembl=ENSCING00000004996.3|UniProtKB=F6WLN1 F6WLN1 LOC100185652 PTHR10139:SF1 DOUBLE-STRAND BREAK REPAIR PROTEIN MRE11 DOUBLE-STRAND BREAK REPAIR PROTEIN MRE11 hydrolase activity, acting on ester bonds#GO:0016788;DNA endonuclease activity#GO:0004520;nuclease activity#GO:0004518;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity#GO:0016787;endonuclease activity#GO:0004519;DNA nuclease activity#GO:0004536;catalytic activity, acting on DNA#GO:0140097 DNA repair#GO:0006281;DNA damage checkpoint signaling#GO:0000077;mitotic cell cycle checkpoint signaling#GO:0007093;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;cell cycle checkpoint signaling#GO:0000075;DNA damage response#GO:0006974;mitotic cell cycle#GO:0000278;nitrogen compound metabolic process#GO:0006807;recombinational repair#GO:0000725;meiosis I cell cycle process#GO:0061982;reproductive process#GO:0022414;intracellular signal transduction#GO:0035556;organic substance metabolic process#GO:0071704;regulation of cell cycle G2/M phase transition#GO:1902749;negative regulation of cell cycle#GO:0045786;regulation of mitotic cell cycle phase transition#GO:1901990;macromolecule metabolic process#GO:0043170;meiotic cell cycle#GO:0051321;regulation of cell cycle phase transition#GO:1901987;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;double-strand break repair via homologous recombination#GO:0000724;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;regulation of cell cycle process#GO:0010564;cellular component organization or biogenesis#GO:0071840;double-strand break repair via nonhomologous end joining#GO:0006303;response to stress#GO:0006950;reproduction#GO:0000003;negative regulation of G2/M transition of mitotic cell cycle#GO:0010972;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;mitotic G2/M transition checkpoint#GO:0044818;sexual reproduction#GO:0019953;mitotic G2 DNA damage checkpoint signaling#GO:0007095;cellular response to stress#GO:0033554;cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;double-strand break repair#GO:0006302;telomere organization#GO:0032200;cell cycle process#GO:0022402;negative regulation of cell cycle process#GO:0010948;mitotic cell cycle process#GO:1903047;telomere maintenance#GO:0000723;negative regulation of mitotic cell cycle phase transition#GO:1901991;organic cyclic compound metabolic process#GO:1901360;meiotic cell cycle process#GO:1903046;signal transduction in response to DNA damage#GO:0042770;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;negative regulation of cell cycle G2/M phase transition#GO:1902750;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of mitotic cell cycle#GO:0045930;cellular process#GO:0009987;DNA integrity checkpoint signaling#GO:0031570;meiotic DNA double-strand break formation#GO:0042138;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;organelle organization#GO:0006996;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;mitotic DNA integrity checkpoint signaling#GO:0044774;regulation of G2/M transition of mitotic cell cycle#GO:0010389;mitotic DNA damage checkpoint signaling#GO:0044773;regulation of mitotic cell cycle#GO:0007346;DNA metabolic process#GO:0006259 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;site of DNA damage#GO:0090734;membrane-bounded organelle#GO:0043227;site of double-strand break#GO:0035861;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000002080.3|UniProtKB=F7AAB5 F7AAB5 PTHR21646:SF46 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE cysteine protease#PC00081;protease#PC00190 CIOIN|Ensembl=ENSCING00000006426.3|UniProtKB=F6QQX7 F6QQX7 PTHR46376:SF2 LEUCINE-ZIPPER-LIKE TRANSCRIPTIONAL REGULATOR 1 DISTRACTED, ISOFORM B cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;basic leucine zipper transcription factor#PC00056 CIOIN|Ensembl=ENSCING00000012977.2|UniProtKB=A0A1W2WJR0 A0A1W2WJR0 LOC100184598 PTHR15090:SF0 SEQUESTOSOME 1-RELATED SEQUESTOSOME-1 K63-linked polyubiquitin modification-dependent protein binding#GO:0070530;binding#GO:0005488;protein binding#GO:0005515;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;modification-dependent protein binding#GO:0140030;polyubiquitin modification-dependent protein binding#GO:0031593;kinase binding#GO:0019900 macroautophagy#GO:0016236;mitophagy#GO:0000423;endomembrane system organization#GO:0010256;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;autophagy of mitochondrion#GO:0000422;cellular process#GO:0009987;organelle disassembly#GO:1903008;process utilizing autophagic mechanism#GO:0061919;cellular component organization or biogenesis#GO:0071840;endosome organization#GO:0007032;cellular component disassembly#GO:0022411;organelle organization#GO:0006996;catabolic process#GO:0009056;vesicle organization#GO:0016050;mitochondrion organization#GO:0007005;autophagy#GO:0006914;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;autophagosome#GO:0005776;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000002202.3|UniProtKB=F6ZQ20 F6ZQ20 PTHR22619:SF0 ZINC FINGER SWIM DOMAIN CONTAINING PROTEIN 4, 5, 6 ZINC FINGER SWIM DOMAIN-CONTAINING PROTEIN 6-LIKE PROTEIN intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;cullin-RING ubiquitin ligase complex#GO:0031461;catalytic complex#GO:1902494;transferase complex#GO:1990234 CIOIN|Ensembl=ENSCING00000022201.1|UniProtKB=H2XWN8 H2XWN8 LOC100179334 PTHR13723:SF304 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE A DISINTEGRIN AND METALLOPROTEINASE WITH THROMBOSPONDIN MOTIFS 2-LIKE PROTEIN hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular component organization or biogenesis#GO:0071840;extracellular structure organization#GO:0043062;external encapsulating structure organization#GO:0045229;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;cellular component organization#GO:0016043;cellular process#GO:0009987;protein metabolic process#GO:0019538;extracellular matrix organization#GO:0030198;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944 metalloprotease#PC00153;protease#PC00190 CIOIN|Ensembl=ENSCING00000006778.3|UniProtKB=F6VEG5 F6VEG5 LOC100177840 PTHR13244:SF7 ZINC FINGER MYND DOMAIN CONTAINING PROTEIN 10 ZINC FINGER MYND DOMAIN-CONTAINING PROTEIN 10 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000014755.2|UniProtKB=F6W8V2 F6W8V2 PTHR43671:SF98 SERINE/THREONINE-PROTEIN KINASE NEK SERINE_THREONINE-PROTEIN KINASE NEK11 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000019864.1|UniProtKB=H2XT98 H2XT98 PTHR22942:SF30 RECA/RAD51/RADA DNA STRAND-PAIRING FAMILY MEMBER MEIOTIC RECOMBINATION PROTEIN DMC1_LIM15 HOMOLOG DNA metabolism protein#PC00009 CIOIN|Ensembl=ENSCING00000005698.3|UniProtKB=F6WQI3 F6WQI3 PTHR13718:SF61 RIBOSOMAL S SUBUNIT SMALL RIBOSOMAL SUBUNIT PROTEIN US5M structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic small ribosomal subunit#GO:0022627;cytosol#GO:0005829;small ribosomal subunit#GO:0015935;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000020760.1|UniProtKB=H2XK43 H2XK43 LOC100179198 PTHR28607:SF4 EXPRESSED PROTEIN TRANSMEMBRANE PROTEIN CIOIN|Ensembl=ENSCING00000022331.1|UniProtKB=H2XUL1 H2XUL1 PTHR11702:SF31 DEVELOPMENTALLY REGULATED GTP-BINDING PROTEIN-RELATED MITOCHONDRIAL RIBOSOME-ASSOCIATED GTPASE 2 GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;ion binding#GO:0043167;anion binding#GO:0043168 CIOIN|Ensembl=ENSCING00000004291.3|UniProtKB=F6UFY6 F6UFY6 PTHR11267:SF195 T-BOX PROTEIN-RELATED OPTOMOTOR-BLIND-RELATED-GENE-1, ISOFORM A sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cell fate commitment#GO:0045165;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;cell fate specification#GO:0001708;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;Rel homology transcription factor#PC00252;immunoglobulin fold transcription factor#PC00251 CIOIN|Ensembl=ENSCING00000024417.1|UniProtKB=H2XVL4 H2XVL4 LOC100180687 PTHR31698:SF8 LYSOZYME G FAMILY MEMBER LYSOZYME G-RELATED CIOIN|Ensembl=ENSCING00000000208.3|UniProtKB=A0A1W5BLB5 A0A1W5BLB5 ciap PTHR11596:SF74 ALKALINE PHOSPHATASE ALKALINE PHOSPHATASE, TISSUE-NONSPECIFIC ISOZYME hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 cellular metabolic process#GO:0044237;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;dephosphorylation#GO:0016311;metabolic process#GO:0008152 phosphatase#PC00181;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000008591.3|UniProtKB=F6UD02 F6UD02 PTHR24099:SF16 E3 UBIQUITIN-PROTEIN LIGASE TRIM36-RELATED E3 UBIQUITIN-PROTEIN LIGASE MIDLINE-1-LIKE ISOFORM X1 ubiquitin-protein ligase#PC00234 CIOIN|Ensembl=ENSCING00000002011.3|UniProtKB=F6WSV3 F6WSV3 LOC100187260 PTHR12317:SF79 DIACYLGLYCEROL O-ACYLTRANSFERASE ACYLTRANSFERASE acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;O-acyltransferase activity#GO:0008374 lipid metabolic process#GO:0006629;triglyceride metabolic process#GO:0006641;glycerolipid biosynthetic process#GO:0045017;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;acylglycerol metabolic process#GO:0006639;lipid biosynthetic process#GO:0008610;primary metabolic process#GO:0044238;neutral lipid metabolic process#GO:0006638;glycerolipid metabolic process#GO:0046486;triglyceride biosynthetic process#GO:0019432;cellular lipid metabolic process#GO:0044255;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 acyltransferase#PC00042 CIOIN|Ensembl=ENSCING00000022481.1|UniProtKB=H2XZT2 H2XZT2 PTHR11214:SF283 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE N-ACETYLLACTOSAMINIDE BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE 4-LIKE transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;protein O-linked glycosylation#GO:0006493;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 bounding membrane of organelle#GO:0098588;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;Golgi membrane#GO:0000139;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111 CIOIN|Ensembl=ENSCING00000022371.1|UniProtKB=H2XMQ0 H2XMQ0 PTHR45828:SF36 CYTOCHROME B561/FERRIC REDUCTASE TRANSMEMBRANE REELIN DOMAIN-CONTAINING PROTEIN cellular anatomical entity#GO:0110165;membrane#GO:0016020 reductase#PC00198;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000009335.3|UniProtKB=H2XUE4 H2XUE4 LOC100183239 PTHR11778:SF7 SERYL-TRNA SYNTHETASE SERINE--TRNA LIGASE, CYTOPLASMIC aminoacyl-tRNA synthetase#PC00047;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000015049.2|UniProtKB=F6S8K0 F6S8K0 PTHR11266:SF17 PEROXISOMAL MEMBRANE PROTEIN 2, PXMP2 MPV17 PROTEIN MPV17 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 transporter#PC00227 CIOIN|Ensembl=ENSCING00000012895.2|UniProtKB=A0A1W2WGU2 A0A1W2WGU2 LOC100184320 PTHR45828:SF36 CYTOCHROME B561/FERRIC REDUCTASE TRANSMEMBRANE REELIN DOMAIN-CONTAINING PROTEIN cellular anatomical entity#GO:0110165;membrane#GO:0016020 reductase#PC00198;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000003929.3|UniProtKB=F7A592 F7A592 PTHR10985:SF77 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, HES-RELATED GH26014P sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of multicellular organismal process#GO:0051239;regulation of cell development#GO:0060284;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regionalization#GO:0003002;developmental process#GO:0032502;multicellular organism development#GO:0007275;regulation of RNA biosynthetic process#GO:2001141;regulation of multicellular organismal development#GO:2000026;regulation of cell differentiation#GO:0045595;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of neurogenesis#GO:0050767;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;regulation of nervous system development#GO:0051960;biological regulation#GO:0065007;anterior/posterior pattern specification#GO:0009952;multicellular organismal process#GO:0032501;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;pattern specification process#GO:0007389;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;basic helix-loop-helix transcription factor#PC00055 CIOIN|Ensembl=ENSCING00000002964.3|UniProtKB=F6R2Y1 F6R2Y1 PTHR24416:SF566 TYROSINE-PROTEIN KINASE RECEPTOR EPIDERMAL GROWTH FACTOR RECEPTOR signaling receptor activity#GO:0038023;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;molecular transducer activity#GO:0060089;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672;transmembrane signaling receptor activity#GO:0004888 negative regulation of biological process#GO:0048519;signal transduction#GO:0007165;neurogenesis#GO:0022008;regulation of phosphate metabolic process#GO:0019220;positive regulation of cellular metabolic process#GO:0031325;developmental process#GO:0032502;positive regulation of molecular function#GO:0044093;positive regulation of cell population proliferation#GO:0008284;regulation of catalytic activity#GO:0050790;nervous system development#GO:0007399;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;system development#GO:0048731;cell differentiation#GO:0030154;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;negative regulation of programmed cell death#GO:0043069;regulation of molecular function#GO:0065009;positive regulation of biological process#GO:0048518;negative regulation of cellular process#GO:0048523;signaling#GO:0023052;regulation of programmed cell death#GO:0043067;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;cellular developmental process#GO:0048869;positive regulation of phosphorylation#GO:0042327;cellular response to stimulus#GO:0051716;regulation of apoptotic process#GO:0042981;regulation of cell population proliferation#GO:0042127;positive regulation of catalytic activity#GO:0043085;multicellular organism development#GO:0007275;positive regulation of phosphorus metabolic process#GO:0010562;cell communication#GO:0007154;cellular process#GO:0009987;negative regulation of apoptotic process#GO:0043066;positive regulation of cellular process#GO:0048522;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphate metabolic process#GO:0045937;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;anatomical structure development#GO:0048856;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;multicellular organismal process#GO:0032501;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 basal plasma membrane#GO:0009925;receptor complex#GO:0043235;protein-containing complex#GO:0032991;plasma membrane region#GO:0098590;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;basal part of cell#GO:0045178;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 EGF receptor signaling pathway#P00018>EGFR#P00542;Cadherin signaling pathway#P00012>EGFR#P00466 CIOIN|Ensembl=ENSCING00000007403.3|UniProtKB=F6RZD9 F6RZD9 PTHR46481:SF10 ZINC FINGER BED DOMAIN-CONTAINING PROTEIN 4 ZINC FINGER BED DOMAIN-CONTAINING PROTEIN 39 CIOIN|Ensembl=ENSCING00000004236.3|UniProtKB=F6YG66 F6YG66 LOC100182180 PTHR10502:SF102 ANNEXIN ANNEXIN B11 lipid binding#GO:0008289;phospholipid binding#GO:0005543;binding#GO:0005488;phosphatidylserine binding#GO:0001786 cytoplasm#GO:0005737;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 calcium-binding protein#PC00060 CIOIN|Ensembl=ENSCING00000012837.2|UniProtKB=F6W350 F6W350 PTHR14932:SF1 RAS GTPASE-RELATED RAB-LIKE PROTEIN 6 carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;anion binding#GO:0043168 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 small GTPase#PC00208;G-protein#PC00020 CIOIN|Ensembl=ENSCING00000014215.2|UniProtKB=F6YKZ8 F6YKZ8 LOC100176208 PTHR10127:SF780 DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING METALLOENDOPEPTIDASE hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000007398.3|UniProtKB=F6UKV2 F6UKV2 PTHR11006:SF60 PROTEIN ARGININE N-METHYLTRANSFERASE PROTEIN ARGININE N-METHYLTRANSFERASE 9 N-methyltransferase activity#GO:0008170;histone modifying activity#GO:0140993;transferase activity#GO:0016740;catalytic activity#GO:0003824;histone methyltransferase activity#GO:0042054;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a protein#GO:0140096;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;protein methyltransferase activity#GO:0008276 protein-DNA complex organization#GO:0071824;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;cellular component organization#GO:0016043;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;methylation#GO:0032259;macromolecule methylation#GO:0043414;nitrogen compound metabolic process#GO:0006807;protein-containing complex organization#GO:0043933;chromatin organization#GO:0006325;protein metabolic process#GO:0019538;chromatin remodeling#GO:0006338;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000013986.2|UniProtKB=F6RI63 F6RI63 PTHR24246:SF27 OLFACTORY RECEPTOR AND ADENOSINE RECEPTOR ADENOSINE RECEPTOR, ISOFORM A G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711 CIOIN|Ensembl=ENSCING00000018340.1|UniProtKB=H2XMK0 H2XMK0 LOC100180075 PTHR14303:SF0 DNA POLYMERASE DELTA SUBUNIT 4 DNA POLYMERASE DELTA SUBUNIT 4 DNA-directed DNA polymerase activity#GO:0003887;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on DNA#GO:0140097;DNA polymerase activity#GO:0034061 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;DNA-templated DNA replication#GO:0006261;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;nucleobase-containing compound biosynthetic process#GO:0034654;DNA biosynthetic process#GO:0071897;DNA synthesis involved in DNA repair#GO:0000731;aromatic compound biosynthetic process#GO:0019438;DNA replication#GO:0006260;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-DNA complex#GO:0032993;catalytic complex#GO:1902494;transferase complex#GO:1990234;replisome#GO:0030894;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622;DNA polymerase complex#GO:0042575;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nuclear replication fork#GO:0043596;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513;replication fork#GO:0005657 DNA-directed DNA polymerase#PC00018 CIOIN|Ensembl=ENSCING00000010722.3|UniProtKB=F6Z465 F6Z465 PTHR19876:SF1 COATOMER COATOMER SUBUNIT ALPHA endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;intra-Golgi vesicle-mediated transport#GO:0006891;macromolecule localization#GO:0033036;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;coated vesicle#GO:0030135;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;vesicle coat#GO:0030120;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;Golgi-associated vesicle membrane#GO:0030660;protein-containing complex#GO:0032991;COPI vesicle coat#GO:0030126;endomembrane system#GO:0012505;membrane coat#GO:0030117;coated vesicle membrane#GO:0030662;COPI-coated vesicle#GO:0030137;Golgi-associated vesicle#GO:0005798;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;coated membrane#GO:0048475;cytoplasmic vesicle membrane#GO:0030659 vesicle coat protein#PC00235 CIOIN|Ensembl=ENSCING00000014363.2|UniProtKB=F7AGE4 F7AGE4 LOC113474870 PTHR12828:SF3 PROTEASOME MATURATION PROTEIN UMP1 PROTEASOME MATURATION PROTEIN protein-containing complex assembly#GO:0065003;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;cellular process#GO:0009987;protein-containing complex organization#GO:0043933 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chaperone#PC00072 CIOIN|Ensembl=ENSCING00000011847.2|UniProtKB=F6ZL23 F6ZL23 LOC100186310 PTHR20955:SF1 PROTEIN JAGUNAL HOMOLOG 1 PROTEIN JAGUNAL HOMOLOG 1 localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;endoplasmic reticulum organization#GO:0007029;establishment of localization#GO:0051234;organelle organization#GO:0006996;transport#GO:0006810;endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000005739.3|UniProtKB=F6Q0N1 F6Q0N1 ets_pointed2 PTHR11849:SF289 ETS ETS-LIKE PROTEIN POINTED transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 PDGF signaling pathway#P00047>Ets#P01167 CIOIN|Ensembl=ENSCING00000016100.2|UniProtKB=F6VIX8 F6VIX8 PTHR11929:SF145 ALPHA- 1,3 -FUCOSYLTRANSFERASE ALPHA-(1,3)-FUCOSYLTRANSFERASE FUT-1 transferase activity#GO:0016740;fucosyltransferase activity#GO:0008417;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 glycosylation#GO:0070085;metabolic process#GO:0008152 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000018209.1|UniProtKB=H2Y0K8 H2Y0K8 PTHR46384:SF1 MOTILE SPERM DOMAIN-CONTAINING PROTEIN 2 MOTILE SPERM DOMAIN-CONTAINING PROTEIN 2 cellular anatomical entity#GO:0110165;organelle membrane contact site#GO:0044232;organelle#GO:0043226;endomembrane system#GO:0012505 CIOIN|Ensembl=ENSCING00000015028.2|UniProtKB=F6SVU6 F6SVU6 PTHR20765:SF1 SOLUTE CARRIER FAMILY 43 MEMBER 3-RELATED EQUILIBRATIVE NUCLEOBASE TRANSPORTER 1 amino acid transporter#PC00046;secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000018906.1|UniProtKB=H2Y0D5 H2Y0D5 LOC100186031 PTHR32315:SF3 ADENINE PHOSPHORIBOSYLTRANSFERASE ADENINE PHOSPHORIBOSYLTRANSFERASE cation binding#GO:0043169;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;transferase activity#GO:0016740;small molecule binding#GO:0036094;glycosyltransferase activity#GO:0016757;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;anion binding#GO:0043168;pentosyltransferase activity#GO:0016763 cellular aromatic compound metabolic process#GO:0006725;purine ribonucleoside monophosphate metabolic process#GO:0009167;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;nucleobase metabolic process#GO:0009112;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;nucleoside monophosphate metabolic process#GO:0009123;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;purine nucleoside monophosphate metabolic process#GO:0009126;purine nucleobase metabolic process#GO:0006144;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;ribose phosphate biosynthetic process#GO:0046390;ribonucleoside monophosphate metabolic process#GO:0009161;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleotide biosynthetic process#GO:0009152;small molecule metabolic process#GO:0044281;nucleobase-containing small molecule metabolic process#GO:0055086 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 Adenine and hypoxanthine salvage pathway#P02723>Adenine phosphoribosyl transferase#P02810 CIOIN|Ensembl=ENSCING00000018199.1|UniProtKB=H2XLP9 H2XLP9 PTHR24372:SF82 GLYCOPROTEIN HORMONE RECEPTOR RICKETS signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 response to organic substance#GO:0010033;positive regulation of adenylate cyclase activity#GO:0045762;regulation of lyase activity#GO:0051339;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;cellular response to stimulus#GO:0051716;regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;cellular response to endogenous stimulus#GO:0071495;cellular response to chemical stimulus#GO:0070887;positive regulation of catalytic activity#GO:0043085;cellular response to organic substance#GO:0071310;regulation of cyclase activity#GO:0031279;positive regulation of molecular function#GO:0044093;cell communication#GO:0007154;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;positive regulation of cyclase activity#GO:0031281;hormone-mediated signaling pathway#GO:0009755;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to endogenous stimulus#GO:0009719;response to hormone#GO:0009725;cellular response to hormone stimulus#GO:0032870;response to chemical#GO:0042221;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of lyase activity#GO:0051349;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 CIOIN|Ensembl=ENSCING00000003415.3|UniProtKB=F6Z4E6 F6Z4E6 PTHR24416:SF611 TYROSINE-PROTEIN KINASE RECEPTOR TYROSINE-PROTEIN KINASE TRANSMEMBRANE RECEPTOR ROR transmembrane signal receptor#PC00197 CIOIN|Ensembl=ENSCING00000013649.2|UniProtKB=F6UBJ9 F6UBJ9 LOC100181290 PTHR11984:SF53 CONNEXIN GAP JUNCTION PROTEIN wide pore channel activity#GO:0022829;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;channel activity#GO:0015267 biological regulation#GO:0065007;regulation of biological process#GO:0050789;cell communication#GO:0007154;cellular process#GO:0009987;cell-cell signaling#GO:0007267;signaling#GO:0023052 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 cell junction protein#PC00070;gap junction#PC00105 CIOIN|Ensembl=ENSCING00000001054.3|UniProtKB=F6U649 F6U649 PTHR11412:SF166 MACROGLOBULIN / COMPLEMENT NTR DOMAIN-CONTAINING PROTEIN protease inhibitor#PC00191 CIOIN|Ensembl=ENSCING00000011859.2|UniProtKB=F6Z2M9 F6Z2M9 PTHR44873:SF1 DNAJ HOMOLOG SUBFAMILY C MEMBER 30, MITOCHONDRIAL DNAJ HOMOLOG SUBFAMILY C MEMBER 30, MITOCHONDRIAL chaperone#PC00072 CIOIN|Ensembl=ENSCING00000016949.2|UniProtKB=F7AK59 F7AK59 PTHR24039:SF58 FIBRILLIN-RELATED EGF-LIKE DOMAIN-CONTAINING PROTEIN extracellular matrix structural protein#PC00103 CIOIN|Ensembl=ENSCING00000024247.1|UniProtKB=H2XLE5 H2XLE5 PTHR19325:SF571 COMPLEMENT COMPONENT-RELATED SUSHI DOMAIN-CONTAINING SUSHI DOMAIN-CONTAINING PROTEIN complement component#PC00078 CIOIN|Ensembl=ENSCING00000008608.3|UniProtKB=F6TNX0 F6TNX0 LOC100182916 PTHR24064:SF577 SOLUTE CARRIER FAMILY 22 MEMBER GH09241P secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000007431.3|UniProtKB=F6S1Q4 F6S1Q4 LOC104265378 PTHR18860:SF159 14-3-3 PROTEIN 14-3-3 PROTEIN ZETA localization#GO:0051179;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular localization#GO:0051641;cellular response to stimulus#GO:0051716;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052;protein localization#GO:0008104 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 Parkinson disease#P00049>14-3-3#P01238;FGF signaling pathway#P00021>14-3-3#P00624;EGF receptor signaling pathway#P00018>14-3-3#P00539;PI3 kinase pathway#P00048>14-3-3#P01206 CIOIN|Ensembl=ENSCING00000009373.3|UniProtKB=F6WXJ5 F6WXJ5 LOC100178137 PTHR48078:SF19 THREONINE DEHYDRATASE, MITOCHONDRIAL-RELATED ACT DOMAIN-CONTAINING PROTEIN lyase activity#GO:0016829;catalytic activity#GO:0003824 branched-chain amino acid metabolic process#GO:0009081;organonitrogen compound catabolic process#GO:1901565;biosynthetic process#GO:0009058;branched-chain amino acid biosynthetic process#GO:0009082;carboxylic acid biosynthetic process#GO:0046394;amino acid catabolic process#GO:0009063;nitrogen compound metabolic process#GO:0006807;alpha-amino acid metabolic process#GO:1901605;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;L-amino acid metabolic process#GO:0170033;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248;organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;proteinogenic amino acid metabolic process#GO:0170039;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;alpha-amino acid biosynthetic process#GO:1901607;aspartate family amino acid metabolic process#GO:0009066;small molecule biosynthetic process#GO:0044283;carboxylic acid metabolic process#GO:0019752;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281 dehydratase#PC00091;lyase#PC00144 Isoleucine biosynthesis#P02748>Threonine dehydratase#P02995 CIOIN|Ensembl=ENSCING00000020761.1|UniProtKB=H2XV84 H2XV84 PTHR24412:SF172 KELCH PROTEIN KELCH-LIKE PROTEIN 10 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000019738.1|UniProtKB=H2Y1H3 H2Y1H3 LOC100184252 PTHR21493:SF9 CGI-141-RELATED/LIPASE CONTAINING PROTEIN GOLGI TRANSPORT PROTEIN 1-RELATED lipase#PC00143;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000013330.2|UniProtKB=F6ZFQ4 F6ZFQ4 PTHR21678:SF0 GROWTH INHIBITION AND DIFFERENTIATION RELATED PROTEIN 88 C3H1-TYPE DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000000177.3|UniProtKB=F6WG20 F6WG20 LOC100177875 PTHR22911:SF6 ACYL-MALONYL CONDENSING ENZYME-RELATED SOLUTE CARRIER FAMILY 35 MEMBER G1 cellular anatomical entity#GO:0110165;membrane#GO:0016020 transporter#PC00227 CIOIN|Ensembl=ENSCING00000003674.4|UniProtKB=F6ZUM5 F6ZUM5 PTHR44653:SF2 DNAJ HOMOLOG SUBFAMILY C MEMBER 1 DNAJ HOMOLOG SUBFAMILY C MEMBER 1 cellular anatomical entity#GO:0110165;endomembrane system#GO:0012505 chaperone#PC00072 CIOIN|Ensembl=ENSCING00000021171.1|UniProtKB=H2XVX2 H2XVX2 PTHR10504:SF131 BACTERICIDAL PERMEABILITY-INCREASING BPI PROTEIN-RELATED BPI2 DOMAIN-CONTAINING PROTEIN defense/immunity protein#PC00090 CIOIN|Ensembl=ENSCING00000004374.3|UniProtKB=F7BDJ0 F7BDJ0 PTHR24327:SF81 HOMEOBOX PROTEIN HOMEOTIC PROTEIN DISTAL-LESS-RELATED sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 homeodomain transcription factor#PC00119 CIOIN|Ensembl=ENSCING00000011564.2|UniProtKB=F6TBD6 F6TBD6 LOC100185968 PTHR10454:SF244 CASPASE CASPASE-6-LIKE cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197;hydrolase activity#GO:0016787;cysteine-type endopeptidase activity involved in apoptotic process#GO:0097153;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0043280;positive regulation of cysteine-type endopeptidase activity#GO:2001056;regulation of protein metabolic process#GO:0051246;regulation of cysteine-type endopeptidase activity#GO:2000116;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;positive regulation of proteolysis#GO:0045862;regulation of biological process#GO:0050789;activation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0006919;positive regulation of programmed cell death#GO:0043068;positive regulation of metabolic process#GO:0009893;regulation of molecular function#GO:0065009;apoptotic process#GO:0006915;cell death#GO:0008219;regulation of hydrolase activity#GO:0051336;positive regulation of peptidase activity#GO:0010952;positive regulation of biological process#GO:0048518;regulation of programmed cell death#GO:0043067;positive regulation of apoptotic process#GO:0043065;regulation of proteolysis#GO:0030162;regulation of apoptotic process#GO:0042981;positive regulation of catalytic activity#GO:0043085;programmed cell death#GO:0012501;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of hydrolase activity#GO:0051345;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;positive regulation of protein metabolic process#GO:0051247;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of endopeptidase activity#GO:0052548;regulation of peptidase activity#GO:0052547;regulation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0043281;positive regulation of endopeptidase activity#GO:0010950;regulation of metabolic process#GO:0019222 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 protease#PC00190;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000018395.1|UniProtKB=H2XNR4 H2XNR4 LOC100187514 PTHR22802:SF396 C-TYPE LECTIN SUPERFAMILY MEMBER C-TYPE LECTIN DOMAIN-CONTAINING PROTEIN membrane traffic protein#PC00150 CIOIN|Ensembl=ENSCING00000008156.3|UniProtKB=F6VEW4 F6VEW4 LOC100185366 PTHR15907:SF161 DUF614 FAMILY PROTEIN-RELATED PLAC8 FAMILY PROTEIN CIOIN|Ensembl=ENSCING00000006004.3|UniProtKB=Q4H3E8 Q4H3E8 Ci-Gsc PTHR24329:SF516 HOMEOBOX PROTEIN ARISTALESS HOMEOBOX PROTEIN GOOSECOID sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 CIOIN|Ensembl=ENSCING00000006158.3|UniProtKB=Q32TF6 Q32TF6 efhc2 PTHR12086:SF11 EF-HAND DOMAIN C-TERMINAL CONTAINING PROTEIN EF-HAND DOMAIN-CONTAINING FAMILY MEMBER C2 calmodulin-related#PC00061 CIOIN|Ensembl=ENSCING00000003830.3|UniProtKB=F6YQL6 F6YQL6 LOC100176177 PTHR11118:SF1 RNA-SPLICING LIGASE RTCB HOMOLOG RNA-SPLICING LIGASE RTCB HOMOLOG catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on RNA#GO:0140098;ligase activity#GO:0016874;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;tRNA metabolic process#GO:0006399;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;tRNA splicing, via endonucleolytic cleavage and ligation#GO:0006388;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 DNA replication#P00017>RFC#P00529 CIOIN|Ensembl=ENSCING00000008700.3|UniProtKB=Q4H3F0 Q4H3F0 Ci-Groucho1 PTHR10814:SF21 TRANSDUCIN-LIKE ENHANCER PROTEIN PROTEIN GROUCHO molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714;protein-macromolecule adaptor activity#GO:0030674 regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;negative regulation of response to stimulus#GO:0048585;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;regulation of canonical Wnt signaling pathway#GO:0060828;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;regulation of Wnt signaling pathway#GO:0030111;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of canonical Wnt signaling pathway#GO:0090090;negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transcription cofactor#PC00217 Wnt signaling pathway#P00057>Transducin-like Enhance of Split 1-3#P01436 CIOIN|Ensembl=ENSCING00000009264.3|UniProtKB=F6S214 F6S214 LOC100186050 PTHR33772:SF1 THYMUS, BRAIN AND TESTES-ASSOCIATED PROTEIN TBATA CIOIN|Ensembl=ENSCING00000011905.2|UniProtKB=F6VYD7 F6VYD7 PTHR24300:SF404 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 2D6-LIKE oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;tetrapyrrole binding#GO:0046906;steroid hydroxylase activity#GO:0008395;oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497;heme binding#GO:0020037 response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;response to chemical#GO:0042221;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 oxygenase#PC00177;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000004527.3|UniProtKB=F7A955 F7A955 PTHR32194:SF0 METALLOPROTEASE TLDD ATP-DEPENDENT PROTEASE SUBUNIT HSLV macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;catabolic process#GO:0009056;organonitrogen compound catabolic process#GO:1901565;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 metalloprotease#PC00153;protease#PC00190 CIOIN|Ensembl=ENSCING00000019723.1|UniProtKB=H2XYP0 H2XYP0 PTHR24034:SF209 EGF-LIKE DOMAIN-CONTAINING PROTEIN EGF-LIKE DOMAIN-CONTAINING PROTEIN extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 CIOIN|Ensembl=ENSCING00000013465.2|UniProtKB=F6SDU1 F6SDU1 PTHR12387:SF0 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 8 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 8 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 peptidase complex#GO:1905368;proteasome accessory complex#GO:0022624;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;proteasome regulatory particle#GO:0005838;catalytic complex#GO:1902494;proteasome regulatory particle, lid subcomplex#GO:0008541;proteasome complex#GO:0000502;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endopeptidase complex#GO:1905369;membrane-bounded organelle#GO:0043227 protease#PC00190;protein modifying enzyme#PC00260 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489 CIOIN|Ensembl=ENSCING00000024622.1|UniProtKB=H2XQ19 H2XQ19 PTHR14084:SF0 KYNURENINASE KYNURENINASE hydrolase activity#GO:0016787;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;heterocycle catabolic process#GO:0046700;biogenic amine metabolic process#GO:0006576;organonitrogen compound catabolic process#GO:1901565;cellular nitrogen compound catabolic process#GO:0044270;amino acid catabolic process#GO:0009063;organic cyclic compound metabolic process#GO:1901360;aromatic amino acid metabolic process#GO:0009072;nitrogen compound metabolic process#GO:0006807;alpha-amino acid metabolic process#GO:1901605;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248;heterocycle metabolic process#GO:0046483;amine metabolic process#GO:0009308;oxoacid metabolic process#GO:0043436;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;aromatic compound catabolic process#GO:0019439;organic cyclic compound catabolic process#GO:1901361;aromatic amino acid family catabolic process#GO:0009074;carboxylic acid metabolic process#GO:0019752;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000005266.3|UniProtKB=F6V8A8 F6V8A8 PTHR22968:SF24 PROTEIN KINASE C, MU SERINE_THREONINE-PROTEIN KINASE transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;signaling#GO:0023052 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 VEGF signaling pathway#P00056>PKC#P01425;Angiogenesis#P00005>PKC#P00219;EGF receptor signaling pathway#P00018>PKC#P00565 CIOIN|Ensembl=ENSCING00000021084.1|UniProtKB=H2XPD2 H2XPD2 LOC100183704 PTHR10502:SF102 ANNEXIN ANNEXIN B11 lipid binding#GO:0008289;phospholipid binding#GO:0005543;binding#GO:0005488;phosphatidylserine binding#GO:0001786 cytoplasm#GO:0005737;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 calcium-binding protein#PC00060 CIOIN|Ensembl=ENSCING00000005129.4|UniProtKB=C4B8W8 C4B8W8 Ci-CMUB116 PTHR21074:SF0 IQ AND UBIQUITIN-LIKE DOMAIN-CONTAINING PROTEIN IQ AND UBIQUITIN-LIKE DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000007625.3|UniProtKB=F6SIG7 F6SIG7 PTHR13847:SF200 SARCOSINE DEHYDROGENASE-RELATED SARCOSINE DEHYDROGENASE, MITOCHONDRIAL oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 oxoacid metabolic process#GO:0043436;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;amino acid catabolic process#GO:0009063;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;nitrogen compound metabolic process#GO:0006807;cellular modified amino acid metabolic process#GO:0006575;alpha-amino acid metabolic process#GO:1901605;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;carboxylic acid metabolic process#GO:0019752;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 dehydrogenase#PC00092;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000001234.3|UniProtKB=F6SBC7 F6SBC7 LOC100175879 PTHR11932:SF126 CULLIN CULLIN 4, ISOFORM A enzyme binding#GO:0019899;protein binding#GO:0005515;ubiquitin protein ligase binding#GO:0031625;binding#GO:0005488;ubiquitin-like protein ligase binding#GO:0044389 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;cullin-RING ubiquitin ligase complex#GO:0031461;transferase complex#GO:1990234 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000003466.3|UniProtKB=H2XRS4 H2XRS4 PTHR21229:SF1 LUNG SEVEN TRANSMEMBRANE RECEPTOR GH17801P localization#GO:0051179;establishment of localization#GO:0051234;transport#GO:0006810 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 G-protein coupled receptor#PC00021 CIOIN|Ensembl=ENSCING00000002109.3|UniProtKB=F6ZR96 F6ZR96 LOC100185308 PTHR21415:SF1 U7 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM11 U7 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM11 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;snRNA binding#GO:0017069;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;mRNA 3'-end processing#GO:0031124;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;mRNA processing#GO:0006397;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 ribonucleoprotein complex#GO:1990904;small nuclear ribonucleoprotein complex#GO:0030532;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA processing factor#PC00147;RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000002307.3|UniProtKB=F6YRA9 F6YRA9 LOC100176150 PTHR32379:SF1 GUANIDINOACETATE N-METHYLTRANSFERASE GUANIDINOACETATE N-METHYLTRANSFERASE methyltransferase activity#GO:0008168;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 methyltransferase#PC00155;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000012626.1|UniProtKB=F6XDW5 F6XDW5 PTHR10036:SF3 CD59 GLYCOPROTEIN PROTEIN SLEEPLESS-RELATED CIOIN|Ensembl=ENSCING00000020946.1|UniProtKB=H2XPC5 H2XPC5 PTHR12220:SF13 50S/60S RIBOSOMAL PROTEIN L16 LARGE RIBOSOMAL SUBUNIT PROTEIN UL16M structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;structural molecule activity#GO:0005198;rRNA binding#GO:0019843;binding#GO:0005488;organic cyclic compound binding#GO:0097159 ribosomal protein#PC00202;translational protein#PC00263 Opioid prodynorphin pathway#P05916>SNARE Complex#P05996;Opioid proenkephalin pathway#P05915>SNARE Complex#P05986;5HT3 type receptor mediated signaling pathway#P04375>SNARE Complex#P04423;Opioid proopiomelanocortin pathway#P05917>SNARE Complex#P06005;Thyrotropin-releasing hormone receptor signaling pathway#P04394>SNARE Complex#P04582;Beta1 adrenergic receptor signaling pathway#P04377>SNARE Complex#P04435;Cortocotropin releasing factor receptor signaling pathway#P04380>SNARE Complex#P04457;Dopamine receptor mediated signaling pathway#P05912>SNARE Complex#P05956;Oxytocin receptor mediated signaling pathway#P04391>SNARE Complex#P04532;5HT2 type receptor mediated signaling pathway#P04374>SNARE Complex#P04415;Beta3 adrenergic receptor signaling pathway#P04379>SNARE Complex#P04447;5HT1 type receptor mediated signaling pathway#P04373>SNARE Complex#P04405;5HT4 type receptor mediated signaling pathway#P04376>SNARE Complex#P04428;Beta2 adrenergic receptor signaling pathway#P04378>SNARE Complex#P04442 CIOIN|Ensembl=ENSCING00000018495.1|UniProtKB=Q5SE06 Q5SE06 elo PTHR11157:SF12 FATTY ACID ACYL TRANSFERASE-RELATED ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN 4 acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824 organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;monocarboxylic acid biosynthetic process#GO:0072330;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;organic acid metabolic process#GO:0006082;membrane lipid biosynthetic process#GO:0046467;sphingolipid metabolic process#GO:0006665;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;fatty acid metabolic process#GO:0006631;membrane lipid metabolic process#GO:0006643;nitrogen compound metabolic process#GO:0006807;small molecule biosynthetic process#GO:0044283;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;sphingolipid biosynthetic process#GO:0030148;fatty acid biosynthetic process#GO:0006633;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 acyltransferase#PC00042 CIOIN|Ensembl=ENSCING00000004417.3|UniProtKB=F6Y4J7 F6Y4J7 PTHR24126:SF63 ANKYRIN REPEAT, PH AND SEC7 DOMAIN CONTAINING PROTEIN SECG-RELATED SUBFAMILY NOT NAMED RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;protein binding#GO:0005515;transcription factor binding#GO:0008134;binding#GO:0005488;DNA-binding transcription factor binding#GO:0140297 regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000007226.3|UniProtKB=H2XL40 H2XL40 PTHR43671:SF92 SERINE/THREONINE-PROTEIN KINASE NEK SERINE_THREONINE-PROTEIN KINASE NEK10 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000013752.1|UniProtKB=Q7YZS7 Q7YZS7 fut13 PTHR13398:SF0 GDP-FUCOSE PROTEIN O-FUCOSYLTRANSFERASE 2 GDP-FUCOSE PROTEIN O-FUCOSYLTRANSFERASE 2 transferase activity#GO:0016740;fucosyltransferase activity#GO:0008417;catalytic activity, acting on a protein#GO:0140096;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000007181.3|UniProtKB=F6ZAE1 F6ZAE1 PTHR23236:SF11 EUKARYOTIC TRANSLATION INITIATION FACTOR 4B/4H EUKARYOTIC TRANSLATION INITIATION FACTOR 4H translation initiation factor#PC00224;translation factor#PC00223 CIOIN|Ensembl=ENSCING00000000504.3|UniProtKB=F6VQ92 F6VQ92 LOC100186416 PTHR19444:SF13 UNC-93 RELATED PROTEIN UNC-93 HOMOLOG A membrane-bound signaling molecule#PC00152 CIOIN|Ensembl=ENSCING00000007891.3|UniProtKB=F6SUC9 F6SUC9 PTHR10574:SF444 NETRIN/LAMININ-RELATED BASEMENT MEMBRANE-SPECIFIC HEPARAN SULFATE PROTEOGLYCAN CORE PROTEIN animal organ morphogenesis#GO:0009887;anatomical structure morphogenesis#GO:0009653;tissue development#GO:0009888;anatomical structure development#GO:0048856;animal organ development#GO:0048513;developmental process#GO:0032502 extracellular matrix protein#PC00102 Integrin signalling pathway#P00034>Laminin#P00947 CIOIN|Ensembl=ENSCING00000003255.3|UniProtKB=F6Z4V3 F6Z4V3 PTHR24418:SF162 TYROSINE-PROTEIN KINASE TYROSINE-PROTEIN KINASE ABL protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 non-receptor tyrosine protein kinase#PC00168 CIOIN|Ensembl=ENSCING00000024700.1|UniProtKB=F6SGT8 F6SGT8 PTHR11616:SF286 SODIUM/CHLORIDE DEPENDENT TRANSPORTER SODIUM- AND CHLORIDE-DEPENDENT NEUTRAL AND BASIC AMINO ACID TRANSPORTER B(0+) inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;organic acid:sodium symporter activity#GO:0005343;organic acid transmembrane transporter activity#GO:0005342;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;organic anion transmembrane transporter activity#GO:0008514;monoatomic cation transmembrane transporter activity#GO:0008324;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;amino acid:sodium symporter activity#GO:0005283;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;branched-chain amino acid transmembrane transporter activity#GO:0015658;organic cation transmembrane transporter activity#GO:0015101;metal ion transmembrane transporter activity#GO:0046873;active monoatomic ion transmembrane transporter activity#GO:0022853;amino acid transmembrane transporter activity#GO:0015171;inorganic cation transmembrane transporter activity#GO:0022890;neutral L-amino acid transmembrane transporter activity#GO:0015175;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294 neutral amino acid transport#GO:0015804;quaternary ammonium group transport#GO:0015697;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;organic anion transport#GO:0015711;amino acid transport#GO:0006865;organic acid transport#GO:0015849;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;amino acid import across plasma membrane#GO:0089718;carboxylic acid transmembrane transport#GO:1905039;localization#GO:0051179;organic substance transport#GO:0071702;import across plasma membrane#GO:0098739;amino acid transmembrane transport#GO:0003333;sodium ion transport#GO:0006814;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;organic cation transport#GO:0015695;monoatomic cation transport#GO:0006812;organic acid transmembrane transport#GO:1903825;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;import into cell#GO:0098657;sodium ion transmembrane transport#GO:0035725 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 primary active transporter#PC00068;transporter#PC00227 CIOIN|Ensembl=ENSCING00000025048.1|UniProtKB=H2XPH8 H2XPH8 PTHR43143:SF1 METALLOPHOSPHOESTERASE, CALCINEURIN SUPERFAMILY SERINE_THREONINE-PROTEIN PHOSPHATASE CPPED1 protein phosphatase#PC00195;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000016631.2|UniProtKB=F6U315 F6U315 PTHR42776:SF4 SERINE PEPTIDASE S9 FAMILY MEMBER ACYLAMINO-ACID-RELEASING ENZYME hydrolase activity#GO:0016787;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171 serine protease#PC00203;protease#PC00190 CIOIN|Ensembl=ENSCING00000005233.2|UniProtKB=F6YHQ3 F6YHQ3 PTHR20973:SF0 NON-SMC ELEMENT 1-RELATED NON-STRUCTURAL MAINTENANCE OF CHROMOSOMES ELEMENT 1 HOMOLOG transferase activity#GO:0016740;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;double-strand break repair via homologous recombination#GO:0000724;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;response to stress#GO:0006950;nitrogen compound metabolic process#GO:0006807;recombinational repair#GO:0000725;cellular response to stress#GO:0033554;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;catalytic complex#GO:1902494;transferase complex#GO:1990234;condensed chromosome#GO:0000793;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000004769.3|UniProtKB=F6PLX9 F6PLX9 PTHR21420:SF3 GDP-FUCOSE PROTEIN O-FUCOSYLTRANSFERASE 1 GDP-FUCOSE PROTEIN O-FUCOSYLTRANSFERASE 1 transferase activity#GO:0016740;fucosyltransferase activity#GO:0008417;catalytic activity, acting on a protein#GO:0140096;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule modification#GO:0043412;regulation of signaling#GO:0023051;protein modification process#GO:0036211;biosynthetic process#GO:0009058;regulation of Notch signaling pathway#GO:0008593;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;regulation of cell communication#GO:0010646;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein glycosylation#GO:0006486;protein O-linked glycosylation#GO:0006493;organonitrogen compound biosynthetic process#GO:1901566;cellular metabolic process#GO:0044237;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;glycosylation#GO:0070085 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 Notch signaling pathway#P00045>Neurotic#P01115 CIOIN|Ensembl=ENSCING00000008928.3|UniProtKB=F6QA84 F6QA84 LOC100186658 PTHR23320:SF158 MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MS4A -RELATED CREB-BINDING PROTEIN-LIKE ISOFORM X1 transporter#PC00227 CIOIN|Ensembl=ENSCING00000007352.3|UniProtKB=F6VZF6 F6VZF6 PTHR10762:SF1 DIPHTHAMIDE BIOSYNTHESIS PROTEIN 2-(3-AMINO-3-CARBOXYPROPYL)HISTIDINE SYNTHASE SUBUNIT 1 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;primary metabolic process#GO:0044238 CIOIN|Ensembl=ENSCING00000007407.3|UniProtKB=F6RZ45 F6RZ45 PTHR28670:SF1 UV-STIMULATED SCAFFOLD PROTEIN A UV-STIMULATED SCAFFOLD PROTEIN A basal RNA polymerase II transcription machinery binding#GO:0001099;RNA polymerase binding#GO:0070063;binding#GO:0005488;RNA polymerase core enzyme binding#GO:0043175;RNA polymerase II complex binding#GO:0000993;protein binding#GO:0005515;enzyme binding#GO:0019899;basal transcription machinery binding#GO:0001098 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;nucleotide-excision repair#GO:0006289;response to light stimulus#GO:0009416;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;response to stress#GO:0006950;response to UV#GO:0009411;nitrogen compound metabolic process#GO:0006807;response to radiation#GO:0009314;response to abiotic stimulus#GO:0009628;cellular response to stress#GO:0033554;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259;metabolic process#GO:0008152 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;chromosome#GO:0005694;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000011556.2|UniProtKB=F6TBT3 F6TBT3 PTHR11785:SF512 AMINO ACID TRANSPORTER SOBREMESA, ISOFORM B L-amino acid transmembrane transporter activity#GO:0015179;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;amino acid transmembrane transporter activity#GO:0015171;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215;organic acid transmembrane transporter activity#GO:0005342 localization#GO:0051179;organic substance transport#GO:0071702;amino acid transmembrane transport#GO:0003333;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;amino acid transport#GO:0006865;organic anion transport#GO:0015711;organic acid transport#GO:0015849;transport#GO:0006810;nitrogen compound transport#GO:0071705;organic acid transmembrane transport#GO:1903825;carboxylic acid transport#GO:0046942;cellular process#GO:0009987;carboxylic acid transmembrane transport#GO:1905039 transporter#PC00227 CIOIN|Ensembl=ENSCING00000016032.2|UniProtKB=A0A1W5BCQ9 A0A1W5BCQ9 LOC100179605 PTHR34436:SF1 CENTROMERE PROTEIN M CENTROMERE PROTEIN M CIOIN|Ensembl=ENSCING00000013678.2|UniProtKB=F6ZDW7 F6ZDW7 PTHR11786:SF0 N-HYDROXYARYLAMINE O-ACETYLTRANSFERASE ARYLAMINE N-ACETYLTRANSFERASE 4-RELATED acetyltransferase#PC00038 CIOIN|Ensembl=ENSCING00000014256.1|UniProtKB=F6XAV8 F6XAV8 PTHR22802:SF379 C-TYPE LECTIN SUPERFAMILY MEMBER CHONDROITIN SULFATE PROTEOGLYCAN 2 ISOFORM X1 membrane traffic protein#PC00150 CIOIN|Ensembl=ENSCING00000019573.1|UniProtKB=H2XQ86 H2XQ86 PTHR10174:SF200 ALPHA-TOCOPHEROL TRANSFER PROTEIN-RELATED RETINALDEHYDE-BINDING PROTEIN 1 phosphatidylinositol bisphosphate binding#GO:1902936;lipid binding#GO:0008289;phosphatidylinositol binding#GO:0035091;phospholipid binding#GO:0005543;phosphatidylinositol phosphate binding#GO:1901981;binding#GO:0005488 cellular anatomical entity#GO:0110165;membrane#GO:0016020 transfer/carrier protein#PC00219 CIOIN|Ensembl=ENSCING00000005644.3|UniProtKB=F6ZQY6 F6ZQY6 PTHR10459:SF60 DNA LIGASE POLY [ADP-RIBOSE] POLYMERASE 2 transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;glycosyltransferase activity#GO:0016757;pentosyltransferase activity#GO:0016763;catalytic activity#GO:0003824 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;double-strand break repair#GO:0006302;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;post-translational protein modification#GO:0043687;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;response to stress#GO:0006950;nitrogen compound metabolic process#GO:0006807;cellular response to stress#GO:0033554;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259;metabolic process#GO:0008152 intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA metabolism protein#PC00009 FAS signaling pathway#P00020>PARP#P00600 CIOIN|Ensembl=ENSCING00000002703.3|UniProtKB=F6UE58 F6UE58 LOC100176517 PTHR18947:SF39 HOOK PROTEINS PROTEIN HOOK cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 cellular localization#GO:0051641;transport#GO:0006810;microtubule cytoskeleton organization#GO:0000226;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;microtubule-based process#GO:0007017;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;cytoskeleton-dependent intracellular transport#GO:0030705;cytoskeleton organization#GO:0007010;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;cytoplasmic microtubule organization#GO:0031122 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150 CIOIN|Ensembl=ENSCING00000002203.3|UniProtKB=F6S4A5 F6S4A5 LOC100179651 PTHR16007:SF15 EPIDIDYMAL MEMBRANE PROTEIN E9-RELATED TRANSMEMBRANE PROTEIN 45B CIOIN|Ensembl=ENSCING00000007732.3|UniProtKB=F6Z0E0 F6Z0E0 LOC100186524 PTHR19919:SF0 WD REPEAT CONTAINING PROTEIN DDB1- AND CUL4-ASSOCIATED FACTOR 7 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000014361.2|UniProtKB=F7AZI0 F7AZI0 PTHR43671:SF104 SERINE/THREONINE-PROTEIN KINASE NEK CALCIUM_CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 1D-RELATED transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000006381.3|UniProtKB=F6RKR7 F6RKR7 PTHR43104:SF2 L-2-HYDROXYGLUTARATE DEHYDROGENASE, MITOCHONDRIAL L-2-HYDROXYGLUTARATE DEHYDROGENASE, MITOCHONDRIAL oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 dehydrogenase#PC00092;oxidoreductase#PC00176 Ornithine degradation#P02758>Aminobutyraldehyde dehydrogenase#P03055 CIOIN|Ensembl=ENSCING00000003908.3|UniProtKB=F6SLU0 F6SLU0 PTHR14191:SF29 PDZ DOMAIN CONTAINING PROTEIN PDZ DOMAIN-CONTAINING PROTEIN protein-membrane adaptor activity#GO:0043495;molecular adaptor activity#GO:0060090;protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102;protein-macromolecule adaptor activity#GO:0030674 localization#GO:0051179;protein localization to plasma membrane#GO:0072659;protein localization to cell periphery#GO:1990778;localization within membrane#GO:0051668;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;protein localization to membrane#GO:0072657;cellular process#GO:0009987;protein localization#GO:0008104 plasma membrane region#GO:0098590;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;apical part of cell#GO:0045177;plasma membrane#GO:0005886;apical plasma membrane#GO:0016324 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000020638.1|UniProtKB=H2XRN2 H2XRN2 LOC100184899 PTHR28524:SF3 SUCCINATE DEHYDROGENASE ASSEMBLY FACTOR 4, MITOCHONDRIAL SUCCINATE DEHYDROGENASE ASSEMBLY FACTOR 4, MITOCHONDRIAL chaperone#PC00072 CIOIN|Ensembl=ENSCING00000005722.3|UniProtKB=F6U2V6 F6U2V6 LOC100183643 PTHR23359:SF105 NUCLEOTIDE KINASE ADENYLATE KINASE 7 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;nucleoside diphosphate kinase activity#GO:0004550;phosphotransferase activity, phosphate group as acceptor#GO:0016776;catalytic activity#GO:0003824;kinase activity#GO:0016301 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 nucleotide kinase#PC00172;kinase#PC00137 CIOIN|Ensembl=ENSCING00000000922.3|UniProtKB=F6U0I8 F6U0I8 PTHR11647:SF1 HYDRANTOINASE/DIHYDROPYRIMIDINASE FAMILY MEMBER COLLAPSIN RESPONSE MEDIATOR PROTEIN metabolite interconversion enzyme#PC00262;hydrolase#PC00121 Axon guidance mediated by semaphorins#P00007>CRMP#P00339;Pyrimidine Metabolism#P02771>Dihydropyrimidinase#P03125 CIOIN|Ensembl=ENSCING00000005262.3|UniProtKB=F6V9L7 F6V9L7 PTHR12215:SF10 PHOSPHOPANTETHEINE TRANSFERASE L-AMINOADIPATE-SEMIALDEHYDE DEHYDROGENASE-PHOSPHOPANTETHEINYL TRANSFERASE transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824 organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;proteinogenic amino acid metabolic process#GO:0170039;proteinogenic amino acid biosynthetic process#GO:0170038;lysine biosynthetic process#GO:0009085;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;aspartate family amino acid biosynthetic process#GO:0009067;alpha-amino acid biosynthetic process#GO:1901607;nitrogen compound metabolic process#GO:0006807;amino acid biosynthetic process#GO:0008652;alpha-amino acid metabolic process#GO:1901605;aspartate family amino acid metabolic process#GO:0009066;small molecule biosynthetic process#GO:0044283;L-amino acid biosynthetic process#GO:0170034;carboxylic acid metabolic process#GO:0019752;L-amino acid metabolic process#GO:0170033;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000003191.3|UniProtKB=Q1RPX1 Q1RPX1 Ci-ZF(C2HC)-2 PTHR10615:SF161 HISTONE ACETYLTRANSFERASE HISTONE ACETYLTRANSFERASE KAT7 histone modifying activity#GO:0140993;acyltransferase activity#GO:0016746;peptide N-acetyltransferase activity#GO:0034212;binding#GO:0005488;catalytic activity#GO:0003824;protein-macromolecule adaptor activity#GO:0030674;N-acyltransferase activity#GO:0016410;molecular adaptor activity#GO:0060090;histone acetyltransferase activity#GO:0004402;transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;N-acetyltransferase activity#GO:0008080;transferase activity#GO:0016740;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;peptide-lysine-N-acetyltransferase activity#GO:0061733;acetyltransferase activity#GO:0016407;chromatin binding#GO:0003682;protein-containing complex binding#GO:0044877;catalytic activity, acting on a protein#GO:0140096 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077;histone modifying enzyme#PC00261 Alzheimer disease-presenilin pathway#P00004>Tip60#P00137 CIOIN|Ensembl=ENSCING00000014006.2|UniProtKB=F7A602 F7A602 LOC100175662 PTHR15071:SF0 MANNOSE-6-PHOSPHATE RECEPTOR FAMILY MEMBER MANNOSE 6-PHOSPHATE RECEPTOR-LIKE PROTEIN 1 membrane traffic protein#PC00150 CIOIN|Ensembl=ENSCING00000002819.3|UniProtKB=F6QQA0 F6QQA0 PTHR12247:SF132 POLYCOMB GROUP PROTEIN POLYCOMB PROTEIN SCM protein binding#GO:0005515;protein-containing complex binding#GO:0044877;histone binding#GO:0042393;binding#GO:0005488;chromatin binding#GO:0003682 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of biosynthetic process#GO:0009890;negative regulation of RNA metabolic process#GO:0051253;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of metabolic process#GO:0009892;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 CIOIN|Ensembl=ENSCING00000020309.1|UniProtKB=H2XZR6 H2XZR6 PTHR47978:SF40 FAMILY NOT NAMED RAS-RELATED PROTEIN RAB-33 GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;ion binding#GO:0043167;anion binding#GO:0043168 cytoplasm#GO:0005737;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 small GTPase#PC00208;G-protein#PC00020 CIOIN|Ensembl=ENSCING00000004243.3|UniProtKB=F6YG96 F6YG96 LOC100187385 PTHR13547:SF1 FAMILY NOT NAMED MITOCHONDRIAL RIBONUCLEASE P CATALYTIC SUBUNIT catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a nucleic acid#GO:0140640;endonuclease activity#GO:0004519;RNA nuclease activity#GO:0004540;RNA endonuclease activity#GO:0004521 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 CIOIN|Ensembl=ENSCING00000010126.3|UniProtKB=F6ZX46 F6ZX46 PTHR46753:SF2 FYVE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 1 FYVE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 1 vesicle transport along microtubule#GO:0047496;cellular localization#GO:0051641;organelle localization#GO:0051640;positive regulation of organelle organization#GO:0010638;regulation of catabolic process#GO:0009894;positive regulation of cellular metabolic process#GO:0031325;transport#GO:0006810;positive regulation of cellular catabolic process#GO:0031331;microtubule-based movement#GO:0007018;regulation of cellular component organization#GO:0051128;regulation of biological process#GO:0050789;positive regulation of metabolic process#GO:0009893;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;cytoskeleton-dependent intracellular transport#GO:0030705;positive regulation of biological process#GO:0048518;establishment of organelle localization#GO:0051656;vesicle localization#GO:0051648;regulation of organelle organization#GO:0033043;regulation of autophagy#GO:0010506;regulation of protein-containing complex disassembly#GO:0043244;regulation of macroautophagy#GO:0016241;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;transport along microtubule#GO:0010970;positive regulation of cellular process#GO:0048522;localization#GO:0051179;microtubule-based transport#GO:0099111;positive regulation of macroautophagy#GO:0016239;microtubule-based process#GO:0007017;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;positive regulation of catabolic process#GO:0009896;positive regulation of cellular component organization#GO:0051130;establishment of localization in cell#GO:0051649;positive regulation of autophagy#GO:0010508;intracellular transport#GO:0046907;regulation of autophagosome maturation#GO:1901096;organelle transport along microtubule#GO:0072384;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;vesicle cytoskeletal trafficking#GO:0099518 endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;organelle#GO:0043226;lytic vacuole#GO:0000323;vesicle#GO:0031982;intracellular organelle#GO:0043229;autophagosome#GO:0005776;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;lysosome#GO:0005764;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;late endosome#GO:0005770 CIOIN|Ensembl=ENSCING00000004245.3|UniProtKB=F6YG77 F6YG77 PTHR24203:SF14 ANKYRIN REPEAT FAMILY PROTEIN ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 10 CIOIN|Ensembl=ENSCING00000004333.3|UniProtKB=Q1RQ01 Q1RQ01 Ci-ZF(UBR)-2 PTHR22990:SF20 F-BOX ONLY PROTEIN F-BOX ONLY PROTEIN 11 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;regulation of apoptotic process#GO:0042981;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent macromolecule catabolic process#GO:0043632;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;biological regulation#GO:0065007;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;regulation of programmed cell death#GO:0043067;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000021163.1|UniProtKB=H2XWS4 H2XWS4 PTHR33680:SF1 OS07G0190500 PROTEIN OS05G0489500 PROTEIN CIOIN|Ensembl=ENSCING00000000913.3|UniProtKB=A0A1W2WPI0 A0A1W2WPI0 LOC100185878 PTHR22175:SF0 SMALL ACIDIC PROTEIN-RELATED SMALL ACIDIC PROTEIN CIOIN|Ensembl=ENSCING00000015311.2|UniProtKB=F6PPC6 F6PPC6 PTHR11346:SF176 GALECTIN 32 KDA BETA-GALACTOSIDE-BINDING LECTIN LEC-3 carbohydrate binding#GO:0030246;binding#GO:0005488 extracellular matrix protein#PC00102 CIOIN|Ensembl=ENSCING00000006077.3|UniProtKB=F6ZFM9 F6ZFM9 PTHR24356:SF422 SERINE/THREONINE-PROTEIN KINASE PROTEIN KINASE DOMAIN-CONTAINING PROTEIN transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular process#GO:0009987;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000025026.1|UniProtKB=H2XP60 H2XP60 PTHR45742:SF8 COMPLEMENT COMPONENT C6 FLOCCULATION PROTEIN FLO11 complement component#PC00078 CIOIN|Ensembl=ENSCING00000006752.3|UniProtKB=F6Y0K7 F6Y0K7 LOC100176927 PTHR48078:SF14 THREONINE DEHYDRATASE, MITOCHONDRIAL-RELATED L-SERINE AMMONIA-LYASE lyase activity#GO:0016829;catalytic activity#GO:0003824 branched-chain amino acid metabolic process#GO:0009081;organonitrogen compound catabolic process#GO:1901565;biosynthetic process#GO:0009058;branched-chain amino acid biosynthetic process#GO:0009082;carboxylic acid biosynthetic process#GO:0046394;amino acid catabolic process#GO:0009063;nitrogen compound metabolic process#GO:0006807;alpha-amino acid metabolic process#GO:1901605;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;L-amino acid metabolic process#GO:0170033;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248;organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;proteinogenic amino acid metabolic process#GO:0170039;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;alpha-amino acid biosynthetic process#GO:1901607;aspartate family amino acid metabolic process#GO:0009066;small molecule biosynthetic process#GO:0044283;carboxylic acid metabolic process#GO:0019752;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281 dehydratase#PC00091;lyase#PC00144 CIOIN|Ensembl=ENSCING00000002816.3|UniProtKB=F6WZS2 F6WZS2 PTHR13954:SF6 IRE1-RELATED NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE tyrosine protein kinase receptor#PC00233 Alzheimer disease-presenilin pathway#P00004>Ire-1#P00144;Alzheimer disease-presenilin pathway#P00004>Ire-1 N-terminal fragment#P00110;Alzheimer disease-presenilin pathway#P00004>Ire-1 C-terminal fragment#P00125 CIOIN|Ensembl=ENSCING00000022997.1|UniProtKB=H2Y2L0 H2Y2L0 LOC100180707 PTHR23088:SF30 NITRILASE-RELATED OMEGA-AMIDASE NIT2 hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824 oxoacid metabolic process#GO:0043436;proteinogenic amino acid metabolic process#GO:0170039;dicarboxylic acid metabolic process#GO:0043648;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;alpha-amino acid metabolic process#GO:1901605;aspartate family amino acid metabolic process#GO:0009066;carboxylic acid metabolic process#GO:0019752;L-amino acid metabolic process#GO:0170033;amino acid metabolic process#GO:0006520;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000008398.3|UniProtKB=F6XS68 F6XS68 PTHR12874:SF29 F-BOX ONLY PROTEIN 48-RELATED F-BOX ONLY PROTEIN 9 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 SCF ubiquitin ligase complex#GO:0019005;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;cullin-RING ubiquitin ligase complex#GO:0031461;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000004786.3|UniProtKB=F6RFB0 F6RFB0 PTHR45819:SF5 CENTAURIN-GAMMA-1A CENTAURIN-GAMMA-1A GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;catalytic activity#GO:0003824;molecular function regulator activity#GO:0098772;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;enzyme activator activity#GO:0008047;ribonucleoside triphosphate phosphatase activity#GO:0017111;enzyme regulator activity#GO:0030234 regulation of GTPase activity#GO:0043087;regulation of molecular function#GO:0065009;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;activation of GTPase activity#GO:0090630;biological regulation#GO:0065007;positive regulation of molecular function#GO:0044093;regulation of hydrolase activity#GO:0051336;regulation of catalytic activity#GO:0050790;positive regulation of hydrolase activity#GO:0051345 GTPase-activating protein#PC00257 CIOIN|Ensembl=ENSCING00000015928.2|UniProtKB=F6XTC5 F6XTC5 PTHR14453:SF67 PARP/ZINC FINGER CCCH TYPE DOMAIN CONTAINING PROTEIN POLY [ADP-RIBOSE] POLYMERASE molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714;protein-macromolecule adaptor activity#GO:0030674 negative regulation of gene expression#GO:0010629;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of biosynthetic process#GO:0009890;negative regulation of metabolic process#GO:0009892;regulation of biological process#GO:0050789;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000001329.3|UniProtKB=F6W9T5 F6W9T5 PTHR10658:SF11 PHOSPHATIDYLINOSITOL TRANSFER PROTEIN VIBRATOR, ISOFORM B transporter#PC00227 CIOIN|Ensembl=ENSCING00000009849.3|UniProtKB=F6V8G3 F6V8G3 PTHR11902:SF30 ENOLASE ENOLASE 4 lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835;hydro-lyase activity#GO:0016836;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;ribonucleoside triphosphate metabolic process#GO:0009199;nucleoside triphosphate metabolic process#GO:0009141;carbohydrate derivative metabolic process#GO:1901135;heterocycle catabolic process#GO:0046700;organonitrogen compound catabolic process#GO:1901565;ribonucleotide catabolic process#GO:0009261;pyridine nucleotide metabolic process#GO:0019362;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;cellular nitrogen compound catabolic process#GO:0044270;purine-containing compound catabolic process#GO:0072523;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;purine nucleotide catabolic process#GO:0006195;ATP metabolic process#GO:0046034;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;purine ribonucleotide catabolic process#GO:0009154;nucleoside phosphate metabolic process#GO:0006753;carbohydrate catabolic process#GO:0016052;purine-containing compound metabolic process#GO:0072521;pyridine-containing compound metabolic process#GO:0072524;catabolic process#GO:0009056;nucleoside diphosphate metabolic process#GO:0009132;organic substance catabolic process#GO:1901575;carbohydrate metabolic process#GO:0005975;purine nucleotide metabolic process#GO:0006163;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;oxoacid metabolic process#GO:0043436;nucleoside phosphate catabolic process#GO:1901292;carbohydrate derivative catabolic process#GO:1901136;purine ribonucleoside triphosphate metabolic process#GO:0009205;generation of precursor metabolites and energy#GO:0006091;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;nucleotide catabolic process#GO:0009166;cellular nitrogen compound metabolic process#GO:0034641;nicotinamide nucleotide metabolic process#GO:0046496;cellular process#GO:0009987;nucleoside diphosphate catabolic process#GO:0009134;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;organophosphate catabolic process#GO:0046434;aromatic compound catabolic process#GO:0019439;glycolytic process#GO:0006096;organic cyclic compound catabolic process#GO:1901361;organophosphate metabolic process#GO:0019637;purine nucleoside triphosphate metabolic process#GO:0009144;nucleobase-containing compound catabolic process#GO:0034655;nucleotide metabolic process#GO:0009117;carboxylic acid metabolic process#GO:0019752;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622 lyase#PC00144 CIOIN|Ensembl=ENSCING00000009969.3|UniProtKB=F6R4I4 F6R4I4 LOC100180846 PTHR12137:SF54 CARBOHYDRATE SULFOTRANSFERASE CARBOHYDRATE SULFOTRANSFERASE sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824 transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000018723.1|UniProtKB=H2XQS8 H2XQS8 PTHR11360:SF284 MONOCARBOXYLATE TRANSPORTER EG:103B4.3 PROTEIN-RELATED transporter#PC00227 CIOIN|Ensembl=ENSCING00000008112.3|UniProtKB=F6YN07 F6YN07 LOC100177202 PTHR10160:SF19 NAD(P) TRANSHYDROGENASE PROTON-TRANSLOCATING NAD(P)(+) TRANSHYDROGENASE nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;oxidoreductase activity, acting on NAD(P)H#GO:0016651;oxidoreductase activity#GO:0016491 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;generation of precursor metabolites and energy#GO:0006091;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;pyridine nucleotide metabolic process#GO:0019362;nicotinamide nucleotide metabolic process#GO:0046496;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;pyridine-containing compound metabolic process#GO:0072524;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;NADP metabolic process#GO:0006739;purine nucleotide metabolic process#GO:0006163;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086 dehydrogenase#PC00092;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000024742.1|UniProtKB=H2XTW5 H2XTW5 PTHR19857:SF19 MITOCHONDRIAL DIVISION PROTEIN 1-RELATED 26S PROTEASOME REGULATORY SUBUNIT RPN14 CIOIN|Ensembl=ENSCING00000024793.1|UniProtKB=H2XY84 H2XY84 PTHR12297:SF18 HYPOXIA-INDUCBILE GENE 1 HIG1 -RELATED HIG1 DOMAIN FAMILY MEMBER 2A cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;mitochondrion organization#GO:0007005;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000004709.3|UniProtKB=H2XUT3 H2XUT3 PTHR46984:SF1 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 71 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 71 CIOIN|Ensembl=ENSCING00000020039.1|UniProtKB=H2XXH0 H2XXH0 PTHR47266:SF9 ENDONUCLEASE-RELATED INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000004348.3|UniProtKB=F7BMM8 F7BMM8 LOC113475749 PTHR24070:SF263 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY RAS-RELATED PROTEIN RAP1 GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;ion binding#GO:0043167;anion binding#GO:0043168 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 small GTPase#PC00208;G-protein#PC00020 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Rap1#P00703;Integrin signalling pathway#P00034>Rap1#P00906;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Rap1#P00734 CIOIN|Ensembl=ENSCING00000007519.3|UniProtKB=F6YF45 F6YF45 LOC100184512 PTHR23338:SF16 SMALL NUCLEAR RIBONUCLEOPROTEIN SM U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM4 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;snRNA binding#GO:0017069;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;RNA processing#GO:0006396;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;protein-RNA complex assembly#GO:0022618;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;spliceosomal snRNP assembly#GO:0000387;P-body assembly#GO:0033962;non-membrane-bounded organelle assembly#GO:0140694;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular component assembly#GO:0022607;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular component organization#GO:0016043;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;ribonucleoprotein complex biogenesis#GO:0022613;mRNA processing#GO:0006397;protein-RNA complex organization#GO:0071826;RNA splicing, via transesterification reactions#GO:0000375 supramolecular complex#GO:0099080;U6 snRNP#GO:0005688;nucleus#GO:0005634;P-body#GO:0000932;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein complex#GO:1990904;ribonucleoprotein granule#GO:0035770;spliceosomal snRNP complex#GO:0097525;small nuclear ribonucleoprotein complex#GO:0030532;protein-containing complex#GO:0032991;spliceosomal tri-snRNP complex#GO:0097526;membrane-bounded organelle#GO:0043227;Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513 RNA splicing factor#PC00148;RNA processing factor#PC00147 CIOIN|Ensembl=ENSCING00000002158.3|UniProtKB=F6TEA7 F6TEA7 PTHR45655:SF10 GUANYLATE CYCLASE SOLUBLE SUBUNIT BETA-2 SOLUBLE GUANYLATE CYCLASE 88E lyase activity#GO:0016829;cyclase activity#GO:0009975;phosphorus-oxygen lyase activity#GO:0016849;catalytic activity#GO:0003824 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;response to abiotic stimulus#GO:0009628;intracellular signaling cassette#GO:0141124;cGMP-mediated signaling#GO:0019934;cellular process#GO:0009987;signaling#GO:0023052;response to oxygen levels#GO:0070482;cyclic-nucleotide-mediated signaling#GO:0019935 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622 guanylate cyclase#PC00114 CIOIN|Ensembl=ENSCING00000007626.3|UniProtKB=F6XND0 F6XND0 PTHR47977:SF20 RAS-RELATED PROTEIN RAB RAS-RELATED PROTEIN RAB-27A GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;anion binding#GO:0043168;ion binding#GO:0043167 positive regulation of secretion#GO:0051047;transport#GO:0006810;positive regulation of transport#GO:0051050;regulation of secretion by cell#GO:1903530;vesicle-mediated transport#GO:0016192;regulation of localization#GO:0032879;cellular process#GO:0009987;regulation of vesicle-mediated transport#GO:0060627;positive regulation of cellular process#GO:0048522;localization#GO:0051179;regulation of biological process#GO:0050789;regulation of transport#GO:0051049;exocytosis#GO:0006887;establishment of localization#GO:0051234;regulation of cellular process#GO:0050794;regulation of secretion#GO:0051046;secretion#GO:0046903;biological regulation#GO:0065007;positive regulation of secretion by cell#GO:1903532;positive regulation of biological process#GO:0048518;export from cell#GO:0140352;regulation of exocytosis#GO:0017157;secretion by cell#GO:0032940 intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;secretory granule#GO:0030141;Golgi apparatus#GO:0005794;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;apical part of cell#GO:0045177;intracellular anatomical structure#GO:0005622;apical plasma membrane#GO:0016324;cytoplasm#GO:0005737;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;plasma membrane region#GO:0098590;membrane-bounded organelle#GO:0043227;transport vesicle#GO:0030133;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 small GTPase#PC00208;G-protein#PC00020 CIOIN|Ensembl=ENSCING00000002361.3|UniProtKB=F6RA92 F6RA92 PTHR10202:SF13 PRESENILIN PRESENILIN HOMOLOG hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 membrane protein proteolysis#GO:0033619;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;membrane protein ectodomain proteolysis#GO:0006509;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 aspartic protease#PC00053;protein modifying enzyme#PC00260 Alzheimer disease-presenilin pathway#P00004>Presenilin N-terminal fragment#P00140;Notch signaling pathway#P00045>Presenilin#P01110;Alzheimer disease-amyloid secretase pathway#P00003>Presenilin N-terminal fragment#P00088;Alzheimer disease-amyloid secretase pathway#P00003>Presenilin C-terminal fragment#P00102;Alzheimer disease-presenilin pathway#P00004>Presenilin C-terminal fragment#P00155;Alzheimer disease-presenilin pathway#P00004>Presenilin#P00129;Alzheimer disease-amyloid secretase pathway#P00003>Presenilin#P00098 CIOIN|Ensembl=ENSCING00000018196.1|UniProtKB=A0A1W5BNS4 A0A1W5BNS4 LOC100180326 PTHR12002:SF116 CLAUDIN CLAUDIN-11-LIKE cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cell-cell junction organization#GO:0045216;cellular component biogenesis#GO:0044085;cell-cell junction assembly#GO:0007043;cell junction organization#GO:0034330;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;cell adhesion#GO:0007155;cellular process#GO:0009987 tight junction#GO:0070160;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cell junction#GO:0030054;bicellular tight junction#GO:0005923;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;apical junction complex#GO:0043296;plasma membrane#GO:0005886 cell junction protein#PC00070;tight junction#PC00214 CIOIN|Ensembl=ENSCING00000021197.1|UniProtKB=H2Y0I8 H2Y0I8 LOC100181499 PTHR13401:SF2 RAGULATOR COMPLEX PROTEIN LAMTOR1 RAGULATOR COMPLEX PROTEIN LAMTOR1 nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 regulation of MAPK cascade#GO:0043408;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;cellular response to nitrogen compound#GO:1901699;regulation of intracellular signal transduction#GO:1902531;positive regulation of MAPK cascade#GO:0043410;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;regulation of signal transduction#GO:0009966;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;response to organonitrogen compound#GO:0010243;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;regulation of macromolecule metabolic process#GO:0060255;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cellular response to organonitrogen compound#GO:0071417;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;vacuolar membrane#GO:0005774;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;guanyl-nucleotide exchange factor complex#GO:0032045 CIOIN|Ensembl=ENSCING00000004966.3|UniProtKB=F6X9G1 F6X9G1 LOC100177329 PTHR10457:SF7 MEVALONATE KINASE/GALACTOKINASE GALACTOKINASE-RELATED transferase activity, transferring phosphorus-containing groups#GO:0016772;carbohydrate kinase activity#GO:0019200;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301 monosaccharide metabolic process#GO:0005996;hexose metabolic process#GO:0019318;carbohydrate metabolic process#GO:0005975;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;primary metabolic process#GO:0044238;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;carbohydrate kinase#PC00065 Fructose galactose metabolism#P02744>Galactokinase#P02960 CIOIN|Ensembl=ENSCING00000009755.3|UniProtKB=F7ABF6 F7ABF6 PTHR22780:SF4 ADAPTIN, ALPHA/GAMMA/EPSILON AP-2 COMPLEX SUBUNIT ALPHA molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 localization#GO:0051179;establishment of localization#GO:0051234;clathrin-dependent endocytosis#GO:0072583;transport#GO:0006810;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;receptor-mediated endocytosis#GO:0006898;cellular process#GO:0009987;import into cell#GO:0098657 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;plasma membrane protein complex#GO:0098797;clathrin vesicle coat#GO:0030125;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;coated vesicle#GO:0030135;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;vesicle coat#GO:0030120;intracellular anatomical structure#GO:0005622;AP-type membrane coat adaptor complex#GO:0030119;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;clathrin-coated vesicle#GO:0030136;endomembrane system#GO:0012505;membrane coat#GO:0030117;coated vesicle membrane#GO:0030662;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;coated membrane#GO:0048475;endocytic vesicle#GO:0030139;cytoplasmic vesicle membrane#GO:0030659;clathrin-coated pit#GO:0005905;plasma membrane#GO:0005886 membrane traffic protein#PC00150 Huntington disease#P00029>alpha-Adaptin#P00782 CIOIN|Ensembl=ENSCING00000019682.1|UniProtKB=H2XVV6 H2XVV6 LOC100185924 PTHR11929:SF145 ALPHA- 1,3 -FUCOSYLTRANSFERASE ALPHA-(1,3)-FUCOSYLTRANSFERASE FUT-1 transferase activity#GO:0016740;fucosyltransferase activity#GO:0008417;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 glycosylation#GO:0070085;metabolic process#GO:0008152 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000016460.2|UniProtKB=F6Z6D3 F6Z6D3 PTHR11214:SF283 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE N-ACETYLLACTOSAMINIDE BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE 4-LIKE transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;protein O-linked glycosylation#GO:0006493;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 bounding membrane of organelle#GO:0098588;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;Golgi membrane#GO:0000139;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111 CIOIN|Ensembl=ENSCING00000001016.3|UniProtKB=Q4H329 Q4H329 Ci-NFYB PTHR11064:SF9 CCAAT-BINDING TRANSCRIPTION FACTOR-RELATED NUCLEAR TRANSCRIPTION FACTOR Y SUBUNIT BETA sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218 CIOIN|Ensembl=ENSCING00000013082.2|UniProtKB=F6SHC7 F6SHC7 LOC100178454 PTHR46989:SF3 USP DOMAIN-CONTAINING PROTEIN USPA DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000020122.1|UniProtKB=H2XPV2 H2XPV2 PTHR14136:SF17 BTB_POZ DOMAIN-CONTAINING PROTEIN KCTD9 BTB_POZ DOMAIN-CONTAINING PROTEIN KCTD9 CIOIN|Ensembl=ENSCING00000019132.1|UniProtKB=H2XQ65 H2XQ65 PTHR22588:SF3 VWFA DOMAIN-CONTAINING PROTEIN VWFA DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000023218.1|UniProtKB=H2XV89 H2XV89 PTHR22802:SF379 C-TYPE LECTIN SUPERFAMILY MEMBER CHONDROITIN SULFATE PROTEOGLYCAN 2 ISOFORM X1 membrane traffic protein#PC00150 CIOIN|Ensembl=ENSCING00000023790.1|UniProtKB=H2XQI5 H2XQI5 LOC100184530 PTHR10099:SF1 PHOSPHORIBOSYLFORMYLGLYCINAMIDINE SYNTHASE PHOSPHORIBOSYLFORMYLGLYCINAMIDINE SYNTHASE ligase activity#GO:0016874;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 De novo purine biosynthesis#P02738>Phosphoribosylformylglycinamide synthase#P02898 CIOIN|Ensembl=ENSCING00000023051.1|UniProtKB=A0A1W3JJ95 A0A1W3JJ95 LOC100179505 PTHR31097:SF2 SI:DKEY-276J7.1 CHROMOSOME 7 OPEN READING FRAME 57 CIOIN|Ensembl=ENSCING00000002171.3|UniProtKB=F6SSI8 F6SSI8 PTHR10188:SF6 L-ASPARAGINASE N(4)-(BETA-N-ACETYLGLUCOSAMINYL)-L-ASPARAGINASE protease#PC00190;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000009088.3|UniProtKB=F6QEH2 F6QEH2 LOC100179526 PTHR45760:SF2 FI19922P1-RELATED FI19922P1-RELATED localization#GO:0051179;establishment of localization#GO:0051234;transport#GO:0006810 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000003669.3|UniProtKB=F6XIQ9 F6XIQ9 LOC100179315 PTHR11879:SF22 ASPARTATE AMINOTRANSFERASE ASPARTATE AMINOTRANSFERASE, MITOCHONDRIAL transaminase#PC00216;transferase#PC00220;metabolite interconversion enzyme#PC00262 Tyrosine biosynthesis#P02784>Aromatic amino acid aminotransferase#P03213;Asparagine and aspartate biosynthesis#P02730>Aspartate aminotransferase#P02854 CIOIN|Ensembl=ENSCING00000004508.3|UniProtKB=F7ATF3 F7ATF3 PTHR31169:SF8 OS05G0300700 PROTEIN ZINC-FINGER DOMAIN OF MONOAMINE-OXIDASE A REPRESSOR R1 PROTEIN membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000009890.3|UniProtKB=F6RAM6 F6RAM6 LOC100186799 PTHR45973:SF9 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT SDS22-RELATED LEUCINE-RICH REPEAT-CONTAINING PROTEIN 46 phosphatase modulator#PC00184 CIOIN|Ensembl=ENSCING00000002658.3|UniProtKB=F6YDF4 F6YDF4 LOC100179556 PTHR42862:SF1 DELTA-1-PYRROLINE-5-CARBOXYLATE DEHYDROGENASE 1, ISOFORM A-RELATED DELTA-1-PYRROLINE-5-CARBOXYLATE DEHYDROGENASE 2, ISOFORM A-RELATED oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 oxoacid metabolic process#GO:0043436;proteinogenic amino acid metabolic process#GO:0170039;dicarboxylic acid metabolic process#GO:0043648;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;amino acid catabolic process#GO:0009063;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;nitrogen compound metabolic process#GO:0006807;glutamate metabolic process#GO:0006536;alpha-amino acid metabolic process#GO:1901605;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;carboxylic acid metabolic process#GO:0019752;L-amino acid metabolic process#GO:0170033;amino acid metabolic process#GO:0006520;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;cytoplasmic side of plasma membrane#GO:0009898;plasma membrane#GO:0005886 dehydrogenase#PC00092;oxidoreductase#PC00176 5-Hydroxytryptamine degredation#P04372>Aldehyde Dehydrogenase#P04402 CIOIN|Ensembl=ENSCING00000008086.3|UniProtKB=F6Z6J2 F6Z6J2 PTHR11904:SF9 METHYLTHIOADENOSINE/PURINE NUCLEOSIDE PHOSPHORYLASE PURINE NUCLEOSIDE PHOSPHORYLASE-RELATED transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;pentosyltransferase activity#GO:0016763 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 nucleotide kinase#PC00172;transferase#PC00220;metabolite interconversion enzyme#PC00262 Adenine and hypoxanthine salvage pathway#P02723>Inosine phosphorylase#P02813;Adenine and hypoxanthine salvage pathway#P02723>Adenine phosphorylase#P02805;Xanthine and guanine salvage pathway#P02788>Guanosine phosphorylase#P03250;Adenine and hypoxanthine salvage pathway#P02723>Deoxyadenosine phosphorylase#P02808;Xanthine and guanine salvage pathway#P02788>Deoxyguanosine phosphorylase#P03248;Adenine and hypoxanthine salvage pathway#P02723>Deoxyinosine phosphorylase#P02812 CIOIN|Ensembl=ENSCING00000003661.3|UniProtKB=F7AX62 F7AX62 PTHR23429:SF0 GLUCOSE-6-PHOSPHATE 1-DEHYDROGENASE G6PD GLUCOSE-6-PHOSPHATE 1-DEHYDROGENASE oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 cellular aromatic compound metabolic process#GO:0006725;monosaccharide metabolic process#GO:0005996;carbohydrate derivative metabolic process#GO:1901135;pyridine nucleotide metabolic process#GO:0019362;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;pyridine-containing compound metabolic process#GO:0072524;carbohydrate metabolic process#GO:0005975;NADP metabolic process#GO:0006739;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;generation of precursor metabolites and energy#GO:0006091;cellular metabolic process#GO:0044237;organonitrogen compound metabolic process#GO:1901564;nicotinamide nucleotide metabolic process#GO:0046496;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;glucose metabolic process#GO:0006006;glucose 6-phosphate metabolic process#GO:0051156;primary metabolic process#GO:0044238;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;hexose metabolic process#GO:0019318;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 dehydrogenase#PC00092;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000014166.2|UniProtKB=A0A1W3JG49 A0A1W3JG49 LOC100180359 PTHR24412:SF172 KELCH PROTEIN KELCH-LIKE PROTEIN 10 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000023586.1|UniProtKB=H2XWR8 H2XWR8 PTHR23114:SF17 M7GPPPN-MRNA HYDROLASE M7GPPPN-MRNA HYDROLASE cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000001333.3|UniProtKB=F6VMS4 F6VMS4 PTHR11706:SF33 SOLUTE CARRIER PROTEIN FAMILY 11 MEMBER NATURAL RESISTANCE-ASSOCIATED MACROPHAGE PROTEIN 2 inorganic molecular entity transmembrane transporter activity#GO:0015318;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;inorganic cation transmembrane transporter activity#GO:0022890;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075 localization#GO:0051179;iron ion transmembrane transport#GO:0034755;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;monoatomic cation transport#GO:0006812;iron ion transport#GO:0006826;transition metal ion transport#GO:0000041;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000002527.3|UniProtKB=F6XS35 F6XS35 PTHR13132:SF29 ALPHA- 1,6 -FUCOSYLTRANSFERASE ALPHA-(1,6)-FUCOSYLTRANSFERASE transferase activity#GO:0016740;fucosyltransferase activity#GO:0008417;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein glycosylation#GO:0006486;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein N-linked glycosylation#GO:0006487;protein metabolic process#GO:0019538;glycosylation#GO:0070085;glycoprotein metabolic process#GO:0009100;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 glycosyltransferase#PC00111 Notch signaling pathway#P00045>Neurotic#P01115 CIOIN|Ensembl=ENSCING00000006753.3|UniProtKB=F6ZGM2 F6ZGM2 PTHR31196:SF2 RNA POLYMERASE II NUCLEAR LOCALIZATION PROTEIN SLC7A6OS-RELATED RNA POLYMERASE II NUCLEAR LOCALIZATION PROTEIN SLC7A6OS-RELATED CIOIN|Ensembl=ENSCING00000020860.1|UniProtKB=H2XKK1 H2XKK1 PTHR12365:SF7 SPROUTY PROTEIN SPROUTY negative regulation of cellular metabolic process#GO:0031324;regulation of MAPK cascade#GO:0043408;negative regulation of biological process#GO:0048519;regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of intracellular signal transduction#GO:1902532;animal organ development#GO:0048513;developmental process#GO:0032502;regulation of signaling#GO:0023051;regulation of catalytic activity#GO:0050790;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;negative regulation of protein phosphorylation#GO:0001933;negative regulation of protein modification process#GO:0031400;negative regulation of MAPK cascade#GO:0043409;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;regulation of protein serine/threonine kinase activity#GO:0071900;regulation of cellular response to growth factor stimulus#GO:0090287;negative regulation of small GTPase mediated signal transduction#GO:0051058;negative regulation of protein kinase activity#GO:0006469;regulation of MAP kinase activity#GO:0043405;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648;regulation of kinase activity#GO:0043549;regulation of protein kinase activity#GO:0045859;regulation of cell communication#GO:0010646;negative regulation of response to stimulus#GO:0048585;negative regulation of phosphorus metabolic process#GO:0010563;negative regulation of signaling#GO:0023057;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of response to stimulus#GO:0048583;regulation of primary metabolic process#GO:0080090;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of phosphorylation#GO:0042326;regulation of protein phosphorylation#GO:0001932;anatomical structure development#GO:0048856;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of phosphate metabolic process#GO:0045936;negative regulation of signal transduction#GO:0009968;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;negative regulation of catalytic activity#GO:0043086;regulation of metabolic process#GO:0019222;negative regulation of molecular function#GO:0044092;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 EGF receptor signaling pathway#P00018>Spry#P00541;EGF receptor signaling pathway#P00018>SPRY#G01511;FGF signaling pathway#P00021>Spry#P00626 CIOIN|Ensembl=ENSCING00000000085.3|UniProtKB=F6TS80 F6TS80 PTHR24299:SF21 CYTOCHROME P450 FAMILY 1 OS09G0441600 PROTEIN oxygenase#PC00177;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000018706.1|UniProtKB=A0A1W2WKY9 A0A1W2WKY9 LOC100182743 PTHR11588:SF499 TUBULIN TUBULIN ALPHA-3 CHAIN carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;structural molecule activity#GO:0005198;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167;structural constituent of cytoskeleton#GO:0005200 cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;microtubule-based process#GO:0007017;organelle organization#GO:0006996;microtubule cytoskeleton organization#GO:0000226;cytoskeleton organization#GO:0007010;cell cycle#GO:0007049;cellular component organization#GO:0016043;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622 tubulin#PC00228;microtubule or microtubule-binding cytoskeletal protein#PC00157 CIOIN|Ensembl=ENSCING00000002644.3|UniProtKB=F7AJ78 F7AJ78 LOC100178847 PTHR45688:SF3 FAMILY NOT NAMED ALANINE--GLYOXYLATE AMINOTRANSFERASE 2, MITOCHONDRIAL CIOIN|Ensembl=ENSCING00000020118.1|UniProtKB=H2XPE2 H2XPE2 PTHR46726:SF1 TWO PORE CHANNEL 3 TWO-PORE CALCIUM CHANNEL 3 ion channel#PC00133;transporter#PC00227 CIOIN|Ensembl=ENSCING00000020657.1|UniProtKB=H2XQR9 H2XQR9 PTHR13137:SF6 DC11 ACN9 HOMOLOG SUCCINATE DEHYDROGENASE ASSEMBLY FACTOR 3, MITOCHONDRIAL oxoacid metabolic process#GO:0043436;cellular component assembly#GO:0022607;dicarboxylic acid metabolic process#GO:0043648;cellular component biogenesis#GO:0044085;mitochondrial respiratory chain complex assembly#GO:0033108;protein-containing complex assembly#GO:0065003;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;cellular component organization or biogenesis#GO:0071840;mitochondrial respiratory chain complex II assembly#GO:0034553;protein-containing complex organization#GO:0043933;organelle organization#GO:0006996;mitochondrion organization#GO:0007005;carboxylic acid metabolic process#GO:0019752;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 envelope#GO:0031975;membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;mitochondrial envelope#GO:0005740;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;mitochondrial intermembrane space#GO:0005758;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000013550.2|UniProtKB=F6WRT4 F6WRT4 PTHR24300:SF397 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 2U1 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;tetrapyrrole binding#GO:0046906;steroid hydroxylase activity#GO:0008395;oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497;heme binding#GO:0020037 response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;response to chemical#GO:0042221;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 oxygenase#PC00177;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000002020.3|UniProtKB=F6WSD2 F6WSD2 PTHR16019:SF6 SYNAPSE-ASSOCIATED PROTEIN SYNAPSE-ASSOCIATED PROTEIN 1 regulation of cell communication#GO:0010646;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of signaling#GO:0023051;cell communication#GO:0007154;TORC2 signaling#GO:0038203;cellular process#GO:0009987;regulation of synaptic plasticity#GO:0048167;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of biological quality#GO:0065008;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;regulation of neuronal synaptic plasticity#GO:0048168;intracellular signal transduction#GO:0035556;signaling#GO:0023052;TOR signaling#GO:0031929 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000013695.2|UniProtKB=F6Y1T4 F6Y1T4 PTHR21274:SF0 MECKELIN MECKELIN organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cell projection organization#GO:0030030;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cilium#GO:0005929;ciliary transition zone#GO:0035869 CIOIN|Ensembl=ENSCING00000021713.1|UniProtKB=H2XZR3 H2XZR3 PTHR23216:SF1 NUCLEOLAR AND COILED-BODY PHOSPHOPROTEIN 1 NUCLEOLAR AND COILED-BODY PHOSPHOPROTEIN 1 CIOIN|Ensembl=ENSCING00000019674.1|UniProtKB=H2XVN3 H2XVN3 PTHR10314:SF241 CYSTATHIONINE BETA-SYNTHASE CYSTEINE SYNTHASE 1 transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824 organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;proteinogenic amino acid metabolic process#GO:0170039;sulfur compound metabolic process#GO:0006790;proteinogenic amino acid biosynthetic process#GO:0170038;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;alpha-amino acid biosynthetic process#GO:1901607;nitrogen compound metabolic process#GO:0006807;amino acid biosynthetic process#GO:0008652;alpha-amino acid metabolic process#GO:1901605;small molecule biosynthetic process#GO:0044283;L-amino acid biosynthetic process#GO:0170034;carboxylic acid metabolic process#GO:0019752;L-amino acid metabolic process#GO:0170033;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 lyase#PC00144 Cysteine biosynthesis#P02737>O-Acetylserine-lyase#P02887 CIOIN|Ensembl=ENSCING00000009241.3|UniProtKB=F6W141 F6W141 PTHR24072:SF73 RHO FAMILY GTPASE MITOCHONDRIAL RHO GTPASE GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;anion binding#GO:0043168;ion binding#GO:0043167 mitochondrion organization#GO:0007005 envelope#GO:0031975;bounding membrane of organelle#GO:0098588;mitochondrial membrane#GO:0031966;intracellular membrane-bounded organelle#GO:0043231;mitochondrial outer membrane#GO:0005741;organelle membrane#GO:0031090;mitochondrion#GO:0005739;organelle#GO:0043226;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867 small GTPase#PC00208 CIOIN|Ensembl=ENSCING00000017649.2|UniProtKB=F6Z541 F6Z541 PTHR45735:SF2 CLEAVAGE STIMULATION FACTOR SUBUNIT 2 CLEAVAGE STIMULATION FACTOR SUBUNIT 2 nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;mRNA cleavage factor complex#GO:0005849;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;mRNA cleavage and polyadenylation specificity factor complex#GO:0005847 mRNA polyadenylation factor#PC00146;RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000005530.3|UniProtKB=Q1RLI4 Q1RLI4 Ci-ArfGAP-1 PTHR46021:SF2 ARF-GAP WITH DUAL PH DOMAIN-CONTAINING PROTEIN 1-LIKE PROTEIN ARF-GAP WITH DUAL PH DOMAIN-CONTAINING PROTEIN 1 nucleoside-triphosphatase regulator activity#GO:0060589;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;small molecule binding#GO:0036094;binding#GO:0005488;molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047;lipid binding#GO:0008289;anion binding#GO:0043168;phosphatidylinositol binding#GO:0035091;ion binding#GO:0043167;phospholipid binding#GO:0005543;phosphatidylinositol phosphate binding#GO:1901981;enzyme regulator activity#GO:0030234 biological regulation#GO:0065007;regulation of hydrolase activity#GO:0051336;regulation of catalytic activity#GO:0050790;regulation of GTPase activity#GO:0043087;regulation of molecular function#GO:0065009 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 CIOIN|Ensembl=ENSCING00000012602.2|UniProtKB=F6XF34 F6XF34 PTHR10157:SF23 DOPAMINE BETA HYDROXYLASE RELATED MOXD1 HOMOLOG 1 hydroxylase#PC00122 CIOIN|Ensembl=ENSCING00000003599.3|UniProtKB=F6UY41 F6UY41 PTHR13140:SF745 MYOSIN UNCONVENTIONAL MYOSIN-VI microfilament motor activity#GO:0000146;cytoskeletal protein binding#GO:0008092;ATP-dependent activity#GO:0140657;binding#GO:0005488;actin filament binding#GO:0051015;cytoskeletal motor activity#GO:0003774;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779 cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;actin filament-based movement#GO:0030048;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987 intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endocytic vesicle#GO:0030139;cytoskeleton#GO:0005856;plasma membrane#GO:0005886 actin binding motor protein#PC00040 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 CIOIN|Ensembl=ENSCING00000016458.2|UniProtKB=F6Z6E4 F6Z6E4 PTHR21230:SF26 VESICLE TRANSPORT V-SNARE PROTEIN VTI1-RELATED VESICLE TRANSPORT THROUGH INTERACTION WITH T-SNARES HOMOLOG 1A molecular adaptor activity#GO:0060090;protein binding#GO:0005515;SNAP receptor activity#GO:0005484;binding#GO:0005488;SNARE binding#GO:0000149;protein-macromolecule adaptor activity#GO:0030674 localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;vesicle fusion#GO:0006906;membrane fusion#GO:0061025;establishment of localization#GO:0051234;membrane organization#GO:0061024;organelle organization#GO:0006996;organelle membrane fusion#GO:0090174;transport#GO:0006810;vesicle-mediated transport#GO:0016192;vesicle organization#GO:0016050;cellular component organization#GO:0016043;cellular process#GO:0009987;organelle fusion#GO:0048284 bounding membrane of organelle#GO:0098588;endosome#GO:0005768;COPII-coated ER to Golgi transport vesicle#GO:0030134;intracellular membrane-bounded organelle#GO:0043231;SNARE complex#GO:0031201;late endosome membrane#GO:0031902;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endosome membrane#GO:0010008;vesicle#GO:0031982;intracellular organelle#GO:0043229;transport vesicle membrane#GO:0030658;endoplasmic reticulum subcompartment#GO:0098827;cytoplasmic vesicle membrane#GO:0030659;late endosome#GO:0005770;membrane protein complex#GO:0098796;ER to Golgi transport vesicle membrane#GO:0012507;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;membrane#GO:0016020;coated vesicle#GO:0030135;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;coated vesicle membrane#GO:0030662;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;transport vesicle#GO:0030133;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 SNARE protein#PC00034 Metabotropic glutamate receptor group III pathway#P00039>SNARE Complex#P01042 CIOIN|Ensembl=ENSCING00000007645.3|UniProtKB=F6VXD9 F6VXD9 PTHR11568:SF1 HEPATOCYTE NUCLEAR FACTOR 1 HEPATOCYTE NUCLEAR FACTOR 1-BETA-LIKE ISOFORM X1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 CIOIN|Ensembl=ENSCING00000016228.2|UniProtKB=F6Z8N3 F6Z8N3 PTHR10953:SF162 UBIQUITIN-ACTIVATING ENZYME E1 SUMO-ACTIVATING ENZYME SUBUNIT 1 ligase activity#GO:0016874;transferase activity#GO:0016740;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877;nucleotidyltransferase activity#GO:0016779;thiosulfate sulfurtransferase activity#GO:0004792;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity, acting on a protein#GO:0140096;sulfurtransferase activity#GO:0016783 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;protein sumoylation#GO:0016925;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;post-translational protein modification#GO:0043687;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 Ubiquitin proteasome pathway#P00060>E1#P01492 CIOIN|Ensembl=ENSCING00000008146.3|UniProtKB=F6VG01 F6VG01 opsin3 PTHR24228:SF72 B2 BRADYKININ RECEPTOR/ANGIOTENSIN II RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 G-protein coupled receptor#PC00021 CIOIN|Ensembl=ENSCING00000016124.2|UniProtKB=F6Q5B7 F6Q5B7 LOC100185164 PTHR13411:SF6 PLASMINOGEN RECEPTOR (KT) PLASMINOGEN RECEPTOR (KT) positive regulation of gene expression#GO:0010628;positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of proteolysis#GO:0030162;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of proteolysis#GO:0045862;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;positive regulation of protein metabolic process#GO:0051247;regulation of cellular biosynthetic process#GO:0031326;positive regulation of metabolic process#GO:0009893;regulation of macromolecule metabolic process#GO:0060255;regulation of biosynthetic process#GO:0009889;regulation of cellular process#GO:0050794;positive regulation of macromolecule biosynthetic process#GO:0010557;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 CIOIN|Ensembl=ENSCING00000020716.1|UniProtKB=H2Y064 H2Y064 PTHR35378:SF1 UNNAMED PRODUCT C2H2-TYPE DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000004947.3|UniProtKB=F7A738 F7A738 PTHR19300:SF61 BETA-1,4-GALACTOSYLTRANSFERASE BETA-1,4-N-ACETYLGALACTOSAMINYLTRANSFERASE galactosyltransferase activity#GO:0008378;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 glycosylation#GO:0070085;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000019985.1|UniProtKB=H2XWE4 H2XWE4 PTHR13718:SF4 RIBOSOMAL S SUBUNIT 40S RIBOSOMAL PROTEIN S2 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic small ribosomal subunit#GO:0022627;cytosol#GO:0005829;small ribosomal subunit#GO:0015935;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000008702.3|UniProtKB=F6WYI9 F6WYI9 LOC100177051 PTHR10678:SF3 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 11/COP9 SIGNALOSOME COMPLEX SUBUNIT 2 COP9 SIGNALOSOME COMPLEX SUBUNIT 2 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;protein modification by small protein removal#GO:0070646;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;post-translational protein modification#GO:0043687;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;COP9 signalosome#GO:0008180;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000017923.1|UniProtKB=H2XRH3 H2XRH3 PTHR11214:SF283 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE N-ACETYLLACTOSAMINIDE BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE 4-LIKE transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;protein O-linked glycosylation#GO:0006493;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 bounding membrane of organelle#GO:0098588;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;Golgi membrane#GO:0000139;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111 CIOIN|Ensembl=ENSCING00000005534.3|UniProtKB=F6Y3N0 F6Y3N0 PTHR13555:SF25 C2H2 ZINC FINGER CGI-62-RELATED ZINC FINGER C2HC DOMAIN-CONTAINING PROTEIN 1A C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 CIOIN|Ensembl=ENSCING00000004371.3|UniProtKB=F7BDH7 F7BDH7 PTHR11091:SF0 OXIDOREDUCTASE-RELATED MALATE DEHYDROGENASE oxidoreductase#PC00176 Pyruvate metabolism#P02772>Malate Dehydrogenase#P03138;TCA cycle#P00051>Malate Dehydrogenase#P01270;Allantoin degradation#P02725>Ureidoglycolate dehydrogenase#P02820 CIOIN|Ensembl=ENSCING00000005934.3|UniProtKB=F6YYX0 F6YYX0 PTHR11785:SF512 AMINO ACID TRANSPORTER SOBREMESA, ISOFORM B L-amino acid transmembrane transporter activity#GO:0015179;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;amino acid transmembrane transporter activity#GO:0015171;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215;organic acid transmembrane transporter activity#GO:0005342 localization#GO:0051179;organic substance transport#GO:0071702;amino acid transmembrane transport#GO:0003333;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;amino acid transport#GO:0006865;organic anion transport#GO:0015711;organic acid transport#GO:0015849;transport#GO:0006810;nitrogen compound transport#GO:0071705;organic acid transmembrane transport#GO:1903825;carboxylic acid transport#GO:0046942;cellular process#GO:0009987;carboxylic acid transmembrane transport#GO:1905039 transporter#PC00227 CIOIN|Ensembl=ENSCING00000003991.1|UniProtKB=F6WKI5 F6WKI5 PTHR13234:SF8 GAMMA-INTERFERON INDUCIBLE LYSOSOMAL THIOL REDUCTASE GILT GAMMA-INTERFERON-INDUCIBLE LYSOSOMAL THIOL REDUCTASE oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 reductase#PC00198;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000013411.2|UniProtKB=F6V3Y5 F6V3Y5 PTHR16165:SF5 NXPE FAMILY MEMBER NXPE FAMILY MEMBER 3 CIOIN|Ensembl=ENSCING00000017681.2|UniProtKB=F6WCG9 F6WCG9 PTHR23282:SF101 APICAL ENDOSOMAL GLYCOPROTEIN PRECURSOR. MAM DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000023669.1|UniProtKB=H2XSH7 H2XSH7 PTHR11941:SF45 ENOYL-COA HYDRATASE-RELATED ENOYL-COA DELTA ISOMERASE 1, MITOCHONDRIAL oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;lipid oxidation#GO:0034440;cellular metabolic process#GO:0044237;lipid catabolic process#GO:0016042;lipid modification#GO:0030258;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;fatty acid catabolic process#GO:0009062;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;fatty acid metabolic process#GO:0006631;small molecule catabolic process#GO:0044282;fatty acid beta-oxidation#GO:0006635;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;cellular lipid metabolic process#GO:0044255;cellular lipid catabolic process#GO:0044242;carboxylic acid metabolic process#GO:0019752;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;monocarboxylic acid catabolic process#GO:0072329 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 hydratase#PC00120 CIOIN|Ensembl=ENSCING00000003725.3|UniProtKB=F6W8D0 F6W8D0 PTHR10972:SF209 OXYSTEROL-BINDING PROTEIN-RELATED OXYSTEROL-BINDING PROTEIN binding#GO:0005488;organic cyclic compound binding#GO:0097159;sterol transporter activity#GO:0015248;steroid binding#GO:0005496;sterol binding#GO:0032934;lipid binding#GO:0008289;lipid transporter activity#GO:0005319;transporter activity#GO:0005215 cytoplasm#GO:0005737;perinuclear region of cytoplasm#GO:0048471;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 transfer/carrier protein#PC00219 CIOIN|Ensembl=ENSCING00000008374.3|UniProtKB=F7A1G9 F7A1G9 PTHR10127:SF856 DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING METALLOENDOPEPTIDASE hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000019911.1|UniProtKB=H2XRA8 H2XRA8 PTHR23063:SF52 PHOSPHOLIPID ACYLTRANSFERASE LYSOPHOSPHATIDYLCHOLINE ACYLTRANSFERASE acyltransferase#PC00042 CIOIN|Ensembl=ENSCING00000005268.3|UniProtKB=F6V890 F6V890 PTHR44305:SF2 SI:DKEY-192D15.2-RELATED SI:DKEY-192D15.2 CIOIN|Ensembl=ENSCING00000018084.1|UniProtKB=H2XVL3 H2XVL3 PTHR24044:SF506 NOTCH LIGAND FAMILY MEMBER NEUROGENIC LOCUS NOTCH HOMOLOG PROTEIN 2-LIKE protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 intercellular signal molecule#PC00207 CIOIN|Ensembl=ENSCING00000006557.3|UniProtKB=F7AR10 F7AR10 PTHR45620:SF36 PDF RECEPTOR-LIKE PROTEIN-RELATED SUBFAMILY NOT NAMED signaling receptor activity#GO:0038023;peptide hormone binding#GO:0017046;binding#GO:0005488;peptide binding#GO:0042277;amide binding#GO:0033218;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled peptide receptor activity#GO:0008528;hormone binding#GO:0042562;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 CIOIN|Ensembl=ENSCING00000000335.3|UniProtKB=F6WEC9 F6WEC9 PTHR13298:SF11 CYTOSOLIC REGULATOR PIANISSIMO RAPAMYCIN-INSENSITIVE COMPANION OF MTOR regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;TORC2 signaling#GO:0038203;cellular process#GO:0009987;signaling#GO:0023052;TOR signaling#GO:0031929 protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535 CIOIN|Ensembl=ENSCING00000023331.1|UniProtKB=H2XN09 H2XN09 LOC100184787 PTHR11214:SF283 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE N-ACETYLLACTOSAMINIDE BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE 4-LIKE transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;protein O-linked glycosylation#GO:0006493;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 bounding membrane of organelle#GO:0098588;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;Golgi membrane#GO:0000139;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111 CIOIN|Ensembl=ENSCING00000012580.2|UniProtKB=F6Y4C2 F6Y4C2 LOC100181811 PTHR11471:SF13 TUMOR NECROSIS FACTOR FAMILY MEMBER TNF FAMILY PROFILE DOMAIN-CONTAINING PROTEIN intercellular signal molecule#PC00207 CIOIN|Ensembl=ENSCING00000000096.3|UniProtKB=F6T5W3 F6T5W3 LOC100182079 PTHR11232:SF77 PHOSPHOTYROSINE INTERACTION DOMAIN-CONTAINING FAMILY MEMBER GULP PTB DOMAIN CONTAINING ENGULFMENT ADAPTOR 1 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000012097.2|UniProtKB=F6XUK1 F6XUK1 PTHR10476:SF40 CHARGED MULTIVESICULAR BODY PROTEIN CHARGED MULTIVESICULAR BODY PROTEIN 2B endosomal transport#GO:0016197;cellular localization#GO:0051641;macromolecule localization#GO:0033036;vacuolar transport#GO:0007034;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;late endosome to vacuole transport#GO:0045324;cellular process#GO:0009987;multivesicular body sorting pathway#GO:0071985;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;endosome transport via multivesicular body sorting pathway#GO:0032509;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endosome membrane#GO:0010008;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle membrane#GO:0030659;late endosome#GO:0005770 membrane traffic protein#PC00150 CIOIN|Ensembl=ENSCING00000005022.3|UniProtKB=F6TXI5 F6TXI5 PTHR43975:SF2 ZGC:101858 EG:BACR7A4.14 PROTEIN-RELATED CIOIN|Ensembl=ENSCING00000009023.3|UniProtKB=F6R854 F6R854 PTHR14781:SF0 INTRAFLAGELLAR TRANSPORT PROTEIN 56 INTRAFLAGELLAR TRANSPORT PROTEIN 56 protein-containing complex binding#GO:0044877;binding#GO:0005488 cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;cilium assembly#GO:0060271;cell projection organization#GO:0030030;transport#GO:0006810;microtubule-based movement#GO:0007018;cellular component organization#GO:0016043;intraciliary transport involved in cilium assembly#GO:0035735;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;transport along microtubule#GO:0010970;cell projection assembly#GO:0030031;intraciliary transport#GO:0042073;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based transport#GO:0099111;microtubule-based process#GO:0007017;establishment of localization#GO:0051234;organelle organization#GO:0006996;cytoskeleton-dependent intracellular transport#GO:0030705;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;protein-containing complex localization#GO:0031503 microtubule organizing center#GO:0005815;ciliary base#GO:0097546;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intraciliary transport particle B#GO:0030992;microtubule cytoskeleton#GO:0015630;ciliary basal body#GO:0036064;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;cell projection#GO:0042995;cilium#GO:0005929;intraciliary transport particle#GO:0030990 CIOIN|Ensembl=ENSCING00000021130.1|UniProtKB=H2XN89 H2XN89 LOC100176337 PTHR15840:SF10 CGI-121 FAMILY MEMBER EKC_KEOPS COMPLEX SUBUNIT TPRKB cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA modification#GO:0009451;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;tRNA modification#GO:0006400;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;tRNA threonylcarbamoyladenosine metabolic process#GO:0070525;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000011364.2|UniProtKB=F6U8Q9 F6U8Q9 PTHR13906:SF4 PORCUPINE LYSOPHOSPHOLIPID ACYLTRANSFERASE 6 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;cellular metabolic process#GO:0044237;lipid modification#GO:0030258;cellular lipid metabolic process#GO:0044255;cellular process#GO:0009987;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;membrane#GO:0016020 transferase#PC00220;acetyltransferase#PC00038;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000008426.3|UniProtKB=F6X1R3 F6X1R3 LOC100182970 PTHR43725:SF47 UDP-GLUCOSE 4-EPIMERASE UDP-GLUCOSE 4-EPIMERASE racemase and epimerase activity, acting on carbohydrates and derivatives#GO:0016857;isomerase activity#GO:0016853;catalytic activity#GO:0003824 monosaccharide metabolic process#GO:0005996;carbohydrate metabolic process#GO:0005975;organic substance metabolic process#GO:0071704;primary metabolic process#GO:0044238;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 epimerase/racemase#PC00096;metabolite interconversion enzyme#PC00262 Fructose galactose metabolism#P02744>UDP Glucose 4 epimerase#P02965 CIOIN|Ensembl=ENSCING00000007509.3|UniProtKB=F6X714 F6X714 PTHR23282:SF142 APICAL ENDOSOMAL GLYCOPROTEIN PRECURSOR. MAM DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000011525.2|UniProtKB=F6W881 F6W881 LOC100178309 PTHR10545:SF29 DIAMINE N-ACETYLTRANSFERASE GH14572P-RELATED acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;N-acetyltransferase activity#GO:0008080;acyltransferase activity#GO:0016746;acetyltransferase activity#GO:0016407;catalytic activity#GO:0003824;N-acyltransferase activity#GO:0016410 acetyltransferase#PC00038 CIOIN|Ensembl=ENSCING00000001178.3|UniProtKB=H2Y0A5 H2Y0A5 LOC100175325 PTHR11847:SF4 RIBOSOMAL PROTEIN L15 LARGE RIBOSOMAL SUBUNIT PROTEIN EL15 structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;structural molecule activity#GO:0005198;binding#GO:0005488;organic cyclic compound binding#GO:0097159 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cytoplasmic translation#GO:0002181;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic large ribosomal subunit#GO:0022625;large ribosomal subunit#GO:0015934;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000008165.3|UniProtKB=F6UQJ9 F6UQJ9 PTHR12957:SF2 DEAD/H BOX POLYPEPTIDE 26/DICE1-RELATED INTEGRATOR COMPLEX SUBUNIT 6 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;snRNA metabolic process#GO:0016073;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;snRNA 3'-end processing#GO:0034472;snRNA processing#GO:0016180;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;integrator complex#GO:0032039 RNA metabolism protein#PC00031;RNA helicase#PC00032 CIOIN|Ensembl=ENSCING00000016195.2|UniProtKB=F6QAU2 F6QAU2 LOC100182129 PTHR12242:SF1 OS02G0130600 PROTEIN-RELATED MYND-TYPE DOMAIN-CONTAINING PROTEIN cellular anatomical entity#GO:0110165;membrane#GO:0016020 CIOIN|Ensembl=ENSCING00000021473.1|UniProtKB=H2XQR1 H2XQR1 LOC100185375 PTHR10196:SF67 SUGAR KINASE SEDOHEPTULOKINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301 organic hydroxy compound metabolic process#GO:1901615;cellular metabolic process#GO:0044237;phosphorylation#GO:0016310;alcohol metabolic process#GO:0006066;cellular process#GO:0009987;carbohydrate metabolic process#GO:0005975;phosphorus metabolic process#GO:0006793;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 carbohydrate kinase#PC00065 CIOIN|Ensembl=ENSCING00000023316.1|UniProtKB=H2XMV2 H2XMV2 LOC100181388 PTHR31328:SF2 BIOGENESIS OF LYSOSOME-RELATED ORGANELLES COMPLEX 1 SUBUNIT 6 BIOGENESIS OF LYSOSOME-RELATED ORGANELLES COMPLEX 1 SUBUNIT 6 localization#GO:0051179;establishment of localization in cell#GO:0051649;cellular localization#GO:0051641;intracellular transport#GO:0046907;cellular process#GO:0009987;establishment of localization#GO:0051234;transport#GO:0006810 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;transport vesicle#GO:0030133;intracellular protein-containing complex#GO:0140535;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000002601.3|UniProtKB=F7B391 F7B391 PTHR10859:SF91 GLYCOSYL TRANSFERASE DOLICHYL-PHOSPHATE BETA-GLUCOSYLTRANSFERASE glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein glycosylation#GO:0006486;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein N-linked glycosylation#GO:0006487;protein metabolic process#GO:0019538;glycosylation#GO:0070085;glycoprotein metabolic process#GO:0009100;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 glycosyltransferase#PC00111 CIOIN|Ensembl=ENSCING00000013520.2|UniProtKB=A0A1W5B8I0 A0A1W5B8I0 LOC100176786 PTHR11711:SF474 ADP RIBOSYLATION FACTOR-RELATED ADP-RIBOSYLATION FACTOR 6 carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167 cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 G-protein#PC00020 CIOIN|Ensembl=ENSCING00000001166.3|UniProtKB=F6YUB3 F6YUB3 LOC100176867 PTHR12893:SF0 GOLGI REASSEMBLY STACKING PROTEIN GRASP GRASP65 endomembrane system organization#GO:0010256;cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;cellular process#GO:0009987;Golgi organization#GO:0007030;organelle organization#GO:0006996 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000023114.1|UniProtKB=H2XSZ6 H2XSZ6 PTHR24166:SF55 ROLLING PEBBLES, ISOFORM B ROLLING PEBBLES, ISOFORM B scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000015247.2|UniProtKB=A0A1W2WEH6 A0A1W2WEH6 LOC100176335 PTHR11188:SF176 ARRESTIN DOMAIN CONTAINING PROTEIN ARRESTIN DOMAIN-CONTAINING PROTEIN 1 localization#GO:0051179;organic substance transport#GO:0071702;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;transport#GO:0006810;protein transport#GO:0015031;nitrogen compound transport#GO:0071705;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000000962.3|UniProtKB=F7ASH4 F7ASH4 PTHR21367:SF1 ARGININE-TRNA-PROTEIN TRANSFERASE 1 ARGINYL-TRNA--PROTEIN TRANSFERASE 1 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 translational protein#PC00263 CIOIN|Ensembl=ENSCING00000024563.1|UniProtKB=H2XW47 H2XW47 PTHR24300:SF397 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 2U1 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;tetrapyrrole binding#GO:0046906;steroid hydroxylase activity#GO:0008395;oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497;heme binding#GO:0020037 response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;response to chemical#GO:0042221;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 oxygenase#PC00177;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000002470.3|UniProtKB=F7B4L8 F7B4L8 LOC100175810 PTHR23412:SF17 STEREOCILIN RELATED OTOANCORIN cell adhesion#GO:0007155;cellular process#GO:0009987;cell-substrate adhesion#GO:0031589;cell-matrix adhesion#GO:0007160 cell surface#GO:0009986;cellular anatomical entity#GO:0110165 cell adhesion molecule#PC00069 CIOIN|Ensembl=ENSCING00000004885.3|UniProtKB=F6SP08 F6SP08 LOC100186192 PTHR13005:SF4 CYSTEINE-RICH HYDROPHOBIC DOMAIN PROTEIN BRAIN X-LINKED PROTEIN CYSTEINE-RICH HYDROPHOBIC PROTEIN CIOIN|Ensembl=ENSCING00000008472.3|UniProtKB=F6TQU2 F6TQU2 PTHR10010:SF46 SOLUTE CARRIER FAMILY 34 SODIUM PHOSPHATE , MEMBER 2-RELATED SODIUM-DEPENDENT PHOSPHATE TRANSPORT PROTEIN 2B secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000005913.3|UniProtKB=F7BNR7 F7BNR7 LOC100184783 PTHR15950:SF15 TRANSCRIPTION COFACTOR VESTIGIAL-LIKE PROTEIN PROTEIN VESTIGIAL transcription cofactor#PC00217 CIOIN|Ensembl=ENSCING00000003218.3|UniProtKB=F7AJG5 F7AJG5 LOC100181838 PTHR24250:SF50 CHYMOTRYPSIN-RELATED PEPTIDASE S1 DOMAIN-CONTAINING PROTEIN hydrolase activity#GO:0016787;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 serine protease#PC00203;protease#PC00190 CIOIN|Ensembl=ENSCING00000006900.3|UniProtKB=F6YAL4 F6YAL4 LOC100184818 PTHR15673:SF2 IQ CALMODULIN-BINDING MOTIF CONTAINING PROTEIN 1 IQ CALMODULIN-BINDING MOTIF-CONTAINING PROTEIN 1 organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cell projection organization#GO:0030030;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cilium#GO:0005929 CIOIN|Ensembl=ENSCING00000002528.3|UniProtKB=F6XS01 F6XS01 PTHR11492:SF8 NUCLEAR FACTOR I NUCLEAR FACTOR I, ISOFORM B sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218 CIOIN|Ensembl=ENSCING00000013156.2|UniProtKB=F6YFI7 F6YFI7 LOC100179858 PTHR22894:SF5 RING-TYPE DOMAIN-CONTAINING PROTEIN RING-TYPE DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000001642.3|UniProtKB=F6YJ69 F6YJ69 PTHR11785:SF389 AMINO ACID TRANSPORTER Y+L AMINO ACID TRANSPORTER 1-LIKE L-amino acid transmembrane transporter activity#GO:0015179;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;amino acid transmembrane transporter activity#GO:0015171;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215;organic acid transmembrane transporter activity#GO:0005342 localization#GO:0051179;organic substance transport#GO:0071702;amino acid transmembrane transport#GO:0003333;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;amino acid transport#GO:0006865;organic anion transport#GO:0015711;organic acid transport#GO:0015849;transport#GO:0006810;nitrogen compound transport#GO:0071705;organic acid transmembrane transport#GO:1903825;carboxylic acid transport#GO:0046942;cellular process#GO:0009987;carboxylic acid transmembrane transport#GO:1905039 transporter#PC00227 CIOIN|Ensembl=ENSCING00000005064.3|UniProtKB=F7A4J1 F7A4J1 LOC100181363 PTHR14002:SF54 ENDOGLIN/TGF-BETA RECEPTOR TYPE III ZONA PELLUCIDA SPERM-BINDING PROTEIN 2 transmembrane signal receptor#PC00197 CIOIN|Ensembl=ENSCING00000013796.2|UniProtKB=F6RDW1 F6RDW1 LOC100177239 PTHR11571:SF224 GLUTATHIONE S-TRANSFERASE HEMATOPOIETIC PROSTAGLANDIN D SYNTHASE glutathione transferase activity#GO:0004364;transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824 sulfur compound metabolic process#GO:0006790;nitrogen compound metabolic process#GO:0006807;peptide metabolic process#GO:0006518;cellular modified amino acid metabolic process#GO:0006575;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular process#GO:0009987;glutathione metabolic process#GO:0006749;amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000007507.3|UniProtKB=F6X728 F6X728 LOC100178195 PTHR15746:SF23 RAB11-RELATED RAB11 INTERACTING PROTEIN, ISOFORM A small GTPase#PC00208;G-protein#PC00020 CIOIN|Ensembl=ENSCING00000004127.3|UniProtKB=F6V828 F6V828 PTHR11686:SF9 GAMMA GLUTAMYL TRANSPEPTIDASE RE13973P hydrolase activity#GO:0016787;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 sulfur compound metabolic process#GO:0006790;peptide metabolic process#GO:0006518;organonitrogen compound metabolic process#GO:1901564;peptide catabolic process#GO:0043171;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;glutathione metabolic process#GO:0006749;sulfur compound catabolic process#GO:0044273;nitrogen compound metabolic process#GO:0006807;cellular modified amino acid metabolic process#GO:0006575;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 protease#PC00190;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000005841.3|UniProtKB=F6V7P8 F6V7P8 PTHR12027:SF91 WNT RELATED PROTO-ONCOGENE WNT-1 molecular function activator activity#GO:0140677;binding#GO:0005488;molecular function regulator activity#GO:0098772;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;cytokine activity#GO:0005125;G protein-coupled receptor binding#GO:0001664;signaling receptor binding#GO:0005102 cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;neurogenesis#GO:0022008;developmental process#GO:0032502;multicellular organism development#GO:0007275;cell communication#GO:0007154;cell fate commitment#GO:0045165;cell-cell signaling by wnt#GO:0198738;nervous system development#GO:0007399;cellular process#GO:0009987;regulation of biological process#GO:0050789;system development#GO:0048731;response to stimulus#GO:0050896;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;neuron differentiation#GO:0030182;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;cell-cell signaling#GO:0007267;signaling#GO:0023052;canonical Wnt signaling pathway#GO:0060070;Wnt signaling pathway#GO:0016055 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 intercellular signal molecule#PC00207 Wnt signaling pathway#P00057>Wnt#P01444;Alzheimer disease-presenilin pathway#P00004>Wnt#P00142;Angiogenesis#P00005>Wnt#P00206;Cadherin signaling pathway#P00012>Wnt#P00474 CIOIN|Ensembl=ENSCING00000003822.3|UniProtKB=F6ZSX6 F6ZSX6 LOC100178499 PTHR22904:SF523 TPR REPEAT CONTAINING PROTEIN STRESS-INDUCED-PHOSPHOPROTEIN 1 heat shock protein binding#GO:0031072;protein binding#GO:0005515;binding#GO:0005488;Hsp90 protein binding#GO:0051879 CIOIN|Ensembl=ENSCING00000019147.1|UniProtKB=H2XSA8 H2XSA8 PTHR24123:SF33 ANKYRIN REPEAT-CONTAINING PROTEIN HOS4 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000006235.3|UniProtKB=F6YCN8 F6YCN8 LOC100185478 PTHR23064:SF72 TROPONIN TROPONIN C, SKELETAL MUSCLE cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 CIOIN|Ensembl=ENSCING00000025185.1|UniProtKB=H2XU29 H2XU29 LOC100179039 PTHR10210:SF45 RIBOSE-PHOSPHATE DIPHOSPHOKINASE FAMILY MEMBER RIBOSE-PHOSPHATE PYROPHOSPHOKINASE 3, CHLOROPLASTIC transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;ribose phosphate biosynthetic process#GO:0046390;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695 nucleotide kinase#PC00172;kinase#PC00137 CIOIN|Ensembl=ENSCING00000004482.3|UniProtKB=F6U397 F6U397 LOC100182123 PTHR31543:SF0 DYNEIN REGULATORY COMPLEX SUBUNIT 4 DYNEIN REGULATORY COMPLEX SUBUNIT 4 supramolecular complex#GO:0099080;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;cellular anatomical entity#GO:0110165;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;endomembrane system#GO:0012505;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;microtubule#GO:0005874 cytoskeletal protein#PC00085;microtubule or microtubule-binding cytoskeletal protein#PC00157 CIOIN|Ensembl=ENSCING00000014832.2|UniProtKB=F7BH60 F7BH60 PTHR46600:SF1 THAP DOMAIN-CONTAINING THAP DOMAIN-CONTAINING PROTEIN 1 zinc finger transcription factor#PC00244 CIOIN|Ensembl=ENSCING00000018516.1|UniProtKB=H2XLI3 H2XLI3 LOC100186675 PTHR34529:SF1 AP-1 COMPLEX-ASSOCIATED REGULATORY PROTEIN AP-1 COMPLEX-ASSOCIATED REGULATORY PROTEIN CIOIN|Ensembl=ENSCING00000005573.3|UniProtKB=Q7YT72 Q7YT72 rcl2 PTHR24072:SF359 RHO FAMILY GTPASE RAS-RELATED PROTEIN RAC1-RELATED GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;enzyme binding#GO:0019899;ribonucleoside triphosphate phosphatase activity#GO:0017111;kinase binding#GO:0019900;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;protein kinase binding#GO:0019901;anion binding#GO:0043168;ion binding#GO:0043167 establishment or maintenance of cell polarity#GO:0007163;regulation of anatomical structure morphogenesis#GO:0022603;regulation of organelle organization#GO:0033043;regulation of cellular component organization#GO:0051128;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of cytoskeleton organization#GO:0051493;regulation of cell shape#GO:0008360;regulation of biological quality#GO:0065008;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;cortical cytoskeleton organization#GO:0030865;biological regulation#GO:0065007;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;regulation of actin filament-based process#GO:0032970 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 small GTPase#PC00208 T cell activation#P00053>rac#P01324;Huntington disease#P00029>Rac#P00775;Cytoskeletal regulation by Rho GTPase#P00016>Rac#P00523;EGF receptor signaling pathway#P00018>Rac#P00564;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Cdc42#P00834;Ras Pathway#P04393>Rac#P04559;Axon guidance mediated by netrin#P00009>Rac#P00366;Integrin signalling pathway#P00034>Rac#P00927;Axon guidance mediated by Slit/Robo#P00008>Rac#P00354;FGF signaling pathway#P00021>Rac#P00645 CIOIN|Ensembl=ENSCING00000009153.3|UniProtKB=F7BB49 F7BB49 LOC100176838 PTHR12936:SF0 ANAPHASE-PROMOTING COMPLEX 10 ANAPHASE-PROMOTING COMPLEX SUBUNIT 10 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein polyubiquitination#GO:0000209;post-translational protein modification#GO:0043687;protein K11-linked ubiquitination#GO:0070979;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cullin-RING ubiquitin ligase complex#GO:0031461;catalytic complex#GO:1902494;transferase complex#GO:1990234;anaphase-promoting complex#GO:0005680;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;nuclear ubiquitin ligase complex#GO:0000152;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 Cell cycle#P00013>APC#P00481 CIOIN|Ensembl=ENSCING00000006051.3|UniProtKB=F6ZZG0 F6ZZG0 PTHR19336:SF9 UNCHARACTERIZED DUF1167 SPINDLE POLE BODY PROTEIN PPC89 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 CIOIN|Ensembl=ENSCING00000007339.3|UniProtKB=F6XZ71 F6XZ71 PTHR24064:SF577 SOLUTE CARRIER FAMILY 22 MEMBER GH09241P secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000007556.3|UniProtKB=F6T8C2 F6T8C2 PTHR11616:SF309 SODIUM/CHLORIDE DEPENDENT TRANSPORTER TRANSPORTER metal ion transport#GO:0030001;transmembrane transport#GO:0055085;amino acid transport#GO:0006865;organic anion transport#GO:0015711;organic acid transport#GO:0015849;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;localization#GO:0051179;organic substance transport#GO:0071702;sodium ion transport#GO:0006814;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;sodium ion transmembrane transport#GO:0035725 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 primary active transporter#PC00068;transporter#PC00227 CIOIN|Ensembl=ENSCING00000015714.2|UniProtKB=F6VWP3 F6VWP3 zf(c2h2)-169 PTHR23226:SF416 ZINC FINGER AND SCAN DOMAIN-CONTAINING FI01424P C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 CIOIN|Ensembl=ENSCING00000012908.2|UniProtKB=F6PSV0 F6PSV0 PTHR15665:SF1 ASTEROID PROTEIN PROTEIN ASTEROID HOMOLOG 1 CIOIN|Ensembl=ENSCING00000001165.3|UniProtKB=F6YB01 F6YB01 PTHR11349:SF91 NUCLEOSIDE DIPHOSPHATE KINASE NUCLEOSIDE DIPHOSPHATE KINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;nucleoside diphosphate kinase activity#GO:0004550;phosphotransferase activity, phosphate group as acceptor#GO:0016776;catalytic activity#GO:0003824;kinase activity#GO:0016301 transferase#PC00220;kinase#PC00137;metabolite interconversion enzyme#PC00262 De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>dTDP kinase#P02919;De novo pyrimidine ribonucleotides biosythesis#P02740>CDP kinase#P02929;De novo pyrimidine ribonucleotides biosythesis#P02740>UDP kinase#P02923;De novo purine biosynthesis#P02738>GDP kinase#P02891;De novo purine biosynthesis#P02738>dADP kinase#P02907;De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>dCDP kinase#P02914;De novo purine biosynthesis#P02738>dGDP kinase#P02889;De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>dUDP kinase#P02912 CIOIN|Ensembl=ENSCING00000003582.3|UniProtKB=F6Y8B5 F6Y8B5 PTHR14002:SF54 ENDOGLIN/TGF-BETA RECEPTOR TYPE III ZONA PELLUCIDA SPERM-BINDING PROTEIN 2 transmembrane signal receptor#PC00197 CIOIN|Ensembl=ENSCING00000013747.2|UniProtKB=F6RKZ1 F6RKZ1 PTHR46729:SF1 LEUKOCYTE RECEPTOR CLUSTER MEMBER 9 LEUKOCYTE RECEPTOR CLUSTER MEMBER 9 CIOIN|Ensembl=ENSCING00000021886.1|UniProtKB=F6UUI8 F6UUI8 LOC113473990 PTHR45904:SF2 TRNA (URACIL-5-)-METHYLTRANSFERASE TRNA (URACIL-5-)-METHYLTRANSFERASE HOMOLOG A nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 RNA metabolism protein#PC00031;RNA methyltransferase#PC00033 CIOIN|Ensembl=ENSCING00000012988.2|UniProtKB=F6VUS5 F6VUS5 LOC100180521 PTHR44442:SF1 3-KETO-STEROID REDUCTASE 3-KETO-STEROID REDUCTASE_17-BETA-HYDROXYSTEROID DEHYDROGENASE 7 oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 sterol metabolic process#GO:0016125;organic hydroxy compound metabolic process#GO:1901615;lipid metabolic process#GO:0006629;steroid metabolic process#GO:0008202;organic cyclic compound metabolic process#GO:1901360;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 reductase#PC00198;metabolite interconversion enzyme#PC00262 Androgen/estrogene/progesterone biosynthesis#P02727>Estradiol 17beta-dehydrogenase#P02826 CIOIN|Ensembl=ENSCING00000004554.3|UniProtKB=F6Y1R8 F6Y1R8 LOC100185660 PTHR10336:SF209 PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C FAMILY PROTEIN PHOSPHOINOSITIDE PHOSPHOLIPASE C lipase activity#GO:0016298;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;phospholipase C activity#GO:0004629;phospholipase activity#GO:0004620;phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578 phospholipase#PC00186 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PLCbetagamma#P00874;Oxytocin receptor mediated signaling pathway#P04391>PLC beta#P04530;Histamine H1 receptor mediated signaling pathway#P04385>PLC#P04484;5HT2 type receptor mediated signaling pathway#P04374>PLC#P04412;Thyrotropin-releasing hormone receptor signaling pathway#P04394>PLC#P04581 CIOIN|Ensembl=ENSCING00000005482.3|UniProtKB=F6PPW9 F6PPW9 LOC100183494 PTHR11959:SF1 4-HYDROXYPHENYLPYRUVATE DIOXYGENASE 4-HYDROXYPHENYLPYRUVATE DIOXYGENASE oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;dioxygenase activity#GO:0051213 cellular aromatic compound metabolic process#GO:0006725;oxoacid metabolic process#GO:0043436;tyrosine metabolic process#GO:0006570;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;aromatic compound catabolic process#GO:0019439;aromatic amino acid metabolic process#GO:0009072;organic cyclic compound metabolic process#GO:1901360;small molecule catabolic process#GO:0044282;nitrogen compound metabolic process#GO:0006807;alpha-amino acid metabolic process#GO:1901605;organic cyclic compound catabolic process#GO:1901361;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;carboxylic acid metabolic process#GO:0019752;aromatic amino acid family catabolic process#GO:0009074;amino acid metabolic process#GO:0006520;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 oxygenase#PC00177;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000009032.3|UniProtKB=F6R7P6 F6R7P6 PTHR45742:SF8 COMPLEMENT COMPONENT C6 FLOCCULATION PROTEIN FLO11 complement component#PC00078 CIOIN|Ensembl=ENSCING00000014904.2|UniProtKB=F6YR85 F6YR85 PTHR14191:SF3 PDZ DOMAIN CONTAINING PROTEIN NA(+)_H(+) EXCHANGE REGULATORY COFACTOR-LIKE PROTEIN NRFL-1 protein-membrane adaptor activity#GO:0043495;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 localization#GO:0051179;protein localization to plasma membrane#GO:0072659;protein localization to cell periphery#GO:1990778;localization within membrane#GO:0051668;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;protein localization to membrane#GO:0072657;cellular process#GO:0009987;protein localization#GO:0008104 plasma membrane region#GO:0098590;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;apical part of cell#GO:0045177;plasma membrane#GO:0005886;apical plasma membrane#GO:0016324 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000006407.3|UniProtKB=F6QWU8 F6QWU8 LOC100179541 PTHR11845:SF13 5'-DEOXYNUCLEOTIDASE HDDC2 5'-DEOXYNUCLEOTIDASE HDDC2 CIOIN|Ensembl=ENSCING00000020711.1|UniProtKB=H2Y0B0 H2Y0B0 PTHR24251:SF30 OVOCHYMASE-RELATED MEMBRANE FRIZZLED-RELATED PROTEIN serine protease#PC00203;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000015858.2|UniProtKB=F6YC40 F6YC40 LOC100185748 PTHR10219:SF25 GLYCOLIPID TRANSFER PROTEIN-RELATED PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY A MEMBER 8 lipid transfer activity#GO:0120013;small molecule binding#GO:0036094;binding#GO:0005488;amide binding#GO:0033218;phospholipid transporter activity#GO:0005548;lipid binding#GO:0008289;ion binding#GO:0043167;anion binding#GO:0043168;phospholipid binding#GO:0005543;transporter activity#GO:0005215;lipid transporter activity#GO:0005319 amide transport#GO:0042886;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;membrane organization#GO:0061024;transport#GO:0006810;nitrogen compound transport#GO:0071705;cellular component organization#GO:0016043;lipid localization#GO:0010876;intermembrane lipid transfer#GO:0120009;cellular process#GO:0009987;lipid transport#GO:0006869 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;membrane#GO:0016020;intracellular anatomical structure#GO:0005622 transfer/carrier protein#PC00219 CIOIN|Ensembl=ENSCING00000003836.3|UniProtKB=F6Z8S6 F6Z8S6 PTHR12375:SF47 RNA-BINDING PROTEIN LUC7-RELATED LUC7-LIKE PROTEIN 3 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;RNA processing#GO:0006396;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;protein-RNA complex assembly#GO:0022618;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular biosynthetic process#GO:0044249;mRNA splice site recognition#GO:0006376;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;protein-containing complex organization#GO:0043933;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;ribonucleoprotein complex biogenesis#GO:0022613;mRNA processing#GO:0006397;protein-RNA complex organization#GO:0071826;RNA splicing, via transesterification reactions#GO:0000375;spliceosomal complex assembly#GO:0000245 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;U1 snRNP#GO:0005685;U2-type spliceosomal complex#GO:0005684;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;spliceosomal snRNP complex#GO:0097525;small nuclear ribonucleoprotein complex#GO:0030532;protein-containing complex#GO:0032991;U2-type prespliceosome#GO:0071004;membrane-bounded organelle#GO:0043227;Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513 CIOIN|Ensembl=ENSCING00000004017.3|UniProtKB=F6PT55 F6PT55 PTHR23150:SF19 SULFATASE MODIFYING FACTOR 1, 2 FORMYLGLYCINE-GENERATING ENZYME oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;protein modification process#GO:0036211;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;primary metabolic process#GO:0044238 CIOIN|Ensembl=ENSCING00000016092.2|UniProtKB=F6VJ60 F6VJ60 LOC100183426 PTHR20855:SF92 ADIPOR/PROGESTIN RECEPTOR-RELATED PROGESTIN AND ADIPOQ RECEPTOR FAMILY MEMBER 3-LIKE signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 G-protein coupled receptor#PC00021 CIOIN|Ensembl=ENSCING00000023721.1|UniProtKB=H2XQ07 H2XQ07 PTHR13596:SF0 SMALL EDRK-RICH FACTOR 1 SI:CH211-39K3.2-RELATED CIOIN|Ensembl=ENSCING00000022245.1|UniProtKB=F6WBD4 F6WBD4 LOC100179269 PTHR19143:SF458 FIBRINOGEN/TENASCIN/ANGIOPOEITIN FIBRINOGEN C-TERMINAL DOMAIN-CONTAINING PROTEIN-RELATED external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 CIOIN|Ensembl=ENSCING00000005672.3|UniProtKB=F6XCK4 F6XCK4 LOC100184688 PTHR23420:SF0 ADENOSYLHOMOCYSTEINASE ADENOSYLHOMOCYSTEINASE hydrolase activity#GO:0016787;catalytic activity#GO:0003824 cellular metabolic process#GO:0044237;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000018287.1|UniProtKB=H2XRK7 H2XRK7 PTHR21683:SF2 COILED-COIL DOMAIN-CONTAINING PROTEIN 42 LIKE-2-LIKE-RELATED COILED-COIL DOMAIN-CONTAINING PROTEIN 42 LIKE-2-LIKE cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 CIOIN|Ensembl=ENSCING00000001777.3|UniProtKB=F6X678 F6X678 PTHR45742:SF8 COMPLEMENT COMPONENT C6 FLOCCULATION PROTEIN FLO11 complement component#PC00078 CIOIN|Ensembl=ENSCING00000006968.3|UniProtKB=F6SZD3 F6SZD3 PTHR10578:SF146 S -2-HYDROXY-ACID OXIDASE-RELATED OXIDASE, PUTATIVE-RELATED oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000007813.3|UniProtKB=A0A1W2W150 A0A1W2W150 LOC100185938 PTHR13848:SF56 PROTEIN YIPPEE-LIKE CG15309-RELATED PROTEIN YIPPEE-LIKE 5 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000008129.3|UniProtKB=F6W2M8 F6W2M8 LOC100176359 PTHR11931:SF0 PHOSPHOGLYCERATE MUTASE PHOSPHOGLYCERATE MUTASE mutase#PC00160 Glycolysis#P00024>Phosphoglyceromutase#P00680 CIOIN|Ensembl=ENSCING00000015479.2|UniProtKB=F6TW46 F6TW46 LOC100181744 PTHR12788:SF10 PROTEIN-TYROSINE SULFOTRANSFERASE 2 PROTEIN-TYROSINE SULFOTRANSFERASE sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000002649.3|UniProtKB=F6YDI9 F6YDI9 LOC100186761 PTHR10625:SF10 HISTONE DEACETYLASE HDAC1-RELATED HISTONE DEACETYLASE HDAC1 histone modifying activity#GO:0140993;histone deacetylase activity#GO:0004407;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;deacetylase activity#GO:0019213;catalytic activity, acting on a protein#GO:0140096 protein-DNA complex organization#GO:0071824;cellular component organization#GO:0016043;cellular process#GO:0009987;epigenetic regulation of gene expression#GO:0040029;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;protein-containing complex organization#GO:0043933;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;chromatin remodeling#GO:0006338;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 Wnt signaling pathway#P00057>Histone deacetylase#P01472;p53 pathway#P00059>HDAC1#P04612 CIOIN|Ensembl=ENSCING00000022960.1|UniProtKB=H2Y3Q1 H2Y3Q1 PTHR22589:SF113 CARNITINE O-ACYLTRANSFERASE CARNITINE O-PALMITOYLTRANSFERASE 1, LIVER ISOFORM-LIKE palmitoyltransferase activity#GO:0016409;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;O-acyltransferase activity#GO:0008374 oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;fatty acid metabolic process#GO:0006631;nitrogen compound metabolic process#GO:0006807;cellular modified amino acid metabolic process#GO:0006575;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transferase#PC00220;acyltransferase#PC00042;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000001056.3|UniProtKB=F6UNM5 F6UNM5 PTHR10288:SF321 KH DOMAIN CONTAINING RNA BINDING PROTEIN MUSHROOM-BODY EXPRESSED, ISOFORM K nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nitrogen compound metabolic process#GO:0051171;regulation of biosynthetic process#GO:0009889;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA metabolic process#GO:0051252;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000008832.3|UniProtKB=F7B0J8 F7B0J8 LOC778840 PTHR12442:SF11 DYNEIN INTERMEDIATE CHAIN DYNEIN AXONEMAL INTERMEDIATE CHAIN 1 protein binding#GO:0005515;binding#GO:0005488 cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;outer dynein arm assembly#GO:0036158;cell projection organization#GO:0030030;microtubule cytoskeleton organization#GO:0000226;microtubule-based movement#GO:0007018;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;axoneme assembly#GO:0035082;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031;cilium movement#GO:0003341;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;microtubule bundle formation#GO:0001578;axonemal dynein complex assembly#GO:0070286;cytoskeleton organization#GO:0007010;plasma membrane bounded cell projection assembly#GO:0120031 axoneme#GO:0005930;outer dynein arm#GO:0036157;catalytic complex#GO:1902494;cytoplasmic region#GO:0099568;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;microtubule associated complex#GO:0005875;axonemal dynein complex#GO:0005858;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;ciliary plasm#GO:0097014;plasma membrane bounded cell projection cytoplasm#GO:0032838;membrane-bounded organelle#GO:0043227;dynein complex#GO:0030286;cell projection#GO:0042995;cytoskeleton#GO:0005856;cilium#GO:0005929 microtubule or microtubule-binding cytoskeletal protein#PC00157 CIOIN|Ensembl=ENSCING00000004302.3|UniProtKB=F6TSS8 F6TSS8 PTHR12753:SF0 AD-003 - RELATED ALPHA N-TERMINAL PROTEIN METHYLTRANSFERASE 1 methyltransferase activity#GO:0008168;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 methyltransferase#PC00155;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000009823.3|UniProtKB=F6Y504 F6Y504 LOC100182488 PTHR14305:SF0 E3 UBIQUITIN-PROTEIN LIGASE CCNB1IP1 E3 UBIQUITIN-PROTEIN LIGASE CCNB1IP1 cellular aromatic compound metabolic process#GO:0006725;nuclear division#GO:0000280;cell cycle process#GO:0022402;nucleobase-containing compound metabolic process#GO:0006139;reciprocal homologous recombination#GO:0140527;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;meiotic cell cycle process#GO:1903046;meiosis I cell cycle process#GO:0061982;reciprocal meiotic recombination#GO:0007131;reproductive process#GO:0022414;meiosis I#GO:0007127;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;meiotic cell cycle#GO:0051321;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;reproduction#GO:0000003;organelle organization#GO:0006996;meiotic nuclear division#GO:0140013;sexual reproduction#GO:0019953;organelle fission#GO:0048285;cell cycle#GO:0007049;homologous recombination#GO:0035825;DNA metabolic process#GO:0006259 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000018996.1|UniProtKB=H2XUK0 H2XUK0 LOC100185988 PTHR15938:SF0 TBP-1 INTERACTING PROTEIN HOMOLOGOUS-PAIRING PROTEIN 2 HOMOLOG nucleic acid binding#GO:0003676;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234 cellular aromatic compound metabolic process#GO:0006725;homologous chromosome segregation#GO:0045143;nuclear division#GO:0000280;cell cycle process#GO:0022402;nucleobase-containing compound metabolic process#GO:0006139;chromosome segregation#GO:0007059;reciprocal homologous recombination#GO:0140527;chromosome organization involved in meiotic cell cycle#GO:0070192;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;meiotic cell cycle process#GO:1903046;meiosis I cell cycle process#GO:0061982;reciprocal meiotic recombination#GO:0007131;reproductive process#GO:0022414;meiosis I#GO:0007127;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;nuclear chromosome segregation#GO:0098813;macromolecule metabolic process#GO:0043170;meiotic cell cycle#GO:0051321;homologous chromosome pairing at meiosis#GO:0007129;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;meiotic chromosome segregation#GO:0045132;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;reproduction#GO:0000003;organelle organization#GO:0006996;chromosome organization#GO:0051276;meiotic nuclear division#GO:0140013;sexual reproduction#GO:0019953;cell cycle#GO:0007049;organelle fission#GO:0048285;homologous recombination#GO:0035825;DNA metabolic process#GO:0006259 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;condensed chromosome#GO:0000793;intracellular organelle lumen#GO:0070013;condensed nuclear chromosome#GO:0000794;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 DNA metabolism protein#PC00009 General transcription by RNA polymerase I#P00022>SL1 complex#P00653;General transcription by RNA polymerase I#P00022>TBP#P00657;General transcription regulation#P00023>TBP#P00670;Transcription regulation by bZIP transcription factor#P00055>TBP#P01399 CIOIN|Ensembl=ENSCING00000007465.3|UniProtKB=F6YIJ5 F6YIJ5 PTHR12989:SF10 ALPHA-1,2-GLUCOSYLTRANSFERASE ALG10 DOL-P-GLC:GLC(2)MAN(9)GLCNAC(2)-PP-DOL ALPHA-1,2-GLUCOSYLTRANSFERASE-RELATED glucosyltransferase activity#GO:0046527;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein N-linked glycosylation#GO:0006487;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000013396.2|UniProtKB=F6PZH8 F6PZH8 PTHR11984:SF53 CONNEXIN GAP JUNCTION PROTEIN wide pore channel activity#GO:0022829;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;channel activity#GO:0015267 biological regulation#GO:0065007;regulation of biological process#GO:0050789;cell communication#GO:0007154;cellular process#GO:0009987;cell-cell signaling#GO:0007267;signaling#GO:0023052 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 cell junction protein#PC00070;gap junction#PC00105 CIOIN|Ensembl=ENSCING00000006672.3|UniProtKB=F6SRA1 F6SRA1 LOC100179385 PTHR12241:SF162 TUBULIN POLYGLUTAMYLASE TUBULIN MONOGLUTAMYLASE TTLL4 cytoskeletal protein binding#GO:0008092;ligase activity#GO:0016874;protein binding#GO:0005515;tubulin binding#GO:0015631;catalytic activity, acting on a protein#GO:0140096;binding#GO:0005488;catalytic activity#GO:0003824 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;microtubule cytoskeleton organization#GO:0000226;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;cellular component organization#GO:0016043;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;nitrogen compound metabolic process#GO:0006807;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;microtubule cytoskeleton#GO:0015630;ciliary basal body#GO:0036064;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;cilium#GO:0005929;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;microtubule or microtubule-binding cytoskeletal protein#PC00157 CIOIN|Ensembl=ENSCING00000000259.3|UniProtKB=F6SF88 F6SF88 PTHR10336:SF36 PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C FAMILY PROTEIN 1-PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE PHOSPHODIESTERASE BETA-4 hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;phospholipase C activity#GO:0004629;phospholipase activity#GO:0004620;phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;calcium ion transmembrane transport#GO:0070588;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;regulation of sequestering of calcium ion#GO:0051282;release of sequestered calcium ion into cytosol#GO:0051209;regulation of localization#GO:0032879;cell communication#GO:0007154;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;calcium ion transport#GO:0006816;localization#GO:0051179;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;establishment of localization#GO:0051234;regulation of cellular process#GO:0050794;monoatomic ion transmembrane transport#GO:0034220;calcium ion transmembrane import into cytosol#GO:0097553;biological regulation#GO:0065007;monoatomic cation transport#GO:0006812;intracellular signal transduction#GO:0035556;monoatomic ion transport#GO:0006811;negative regulation of sequestering of calcium ion#GO:0051283;signaling#GO:0023052;monoatomic cation transmembrane transport#GO:0098655;negative regulation of cellular process#GO:0048523 phospholipase#PC00186 Metabotropic glutamate receptor group I pathway#P00041>PLC#P01053;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PLCbetagamma#P00874;Wnt signaling pathway#P00057>Phospholipase C#P01443;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>PLC#P01068;Thyrotropin-releasing hormone receptor signaling pathway#P04394>PLC#P04581;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Phospholipase C-beta#P00744;EGF receptor signaling pathway#P00018>PLCgamma#P00556;Endothelin signaling pathway#P00019>PLCbeta#P00591;Alpha adrenergic receptor signaling pathway#P00002>PLC#P00073;Oxytocin receptor mediated signaling pathway#P04391>PLC beta#P04530;5HT2 type receptor mediated signaling pathway#P04374>PLC#P04412;Histamine H1 receptor mediated signaling pathway#P04385>PLC#P04484 CIOIN|Ensembl=ENSCING00000018354.1|UniProtKB=H2XPW3 H2XPW3 PTHR24039:SF58 FIBRILLIN-RELATED EGF-LIKE DOMAIN-CONTAINING PROTEIN extracellular matrix structural protein#PC00103 CIOIN|Ensembl=ENSCING00000009965.3|UniProtKB=F6R4Q7 F6R4Q7 LOC100179159 PTHR34917:SF1 RBPJ-INTERACTING AND TUBULIN-ASSOCIATED PROTEIN 1 RBPJ-INTERACTING AND TUBULIN-ASSOCIATED PROTEIN 1 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 regulation of cell communication#GO:0010646;cellular localization#GO:0051641;negative regulation of biological process#GO:0048519;negative regulation of response to stimulus#GO:0048585;transport#GO:0006810;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;cellular process#GO:0009987;negative regulation of Notch signaling pathway#GO:0045746;regulation of Notch signaling pathway#GO:0008593;localization#GO:0051179;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;nuclear export#GO:0051168;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;negative regulation of cellular process#GO:0048523;nuclear transport#GO:0051169;negative regulation of cell communication#GO:0010648 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000020203.1|UniProtKB=H2XYJ6 H2XYJ6 PTHR19282:SF519 TETRASPANIN TETRASPANIN cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000011585.2|UniProtKB=Q4H307 Q4H307 Ci-Orphan Wnt c PTHR12027:SF77 WNT RELATED PROTEIN WNT-5 molecular function activator activity#GO:0140677;binding#GO:0005488;molecular function regulator activity#GO:0098772;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;cytokine activity#GO:0005125;G protein-coupled receptor binding#GO:0001664;signaling receptor binding#GO:0005102 cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;neurogenesis#GO:0022008;developmental process#GO:0032502;multicellular organism development#GO:0007275;cell communication#GO:0007154;cell fate commitment#GO:0045165;cell-cell signaling by wnt#GO:0198738;nervous system development#GO:0007399;cellular process#GO:0009987;regulation of biological process#GO:0050789;system development#GO:0048731;response to stimulus#GO:0050896;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;neuron differentiation#GO:0030182;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;cell-cell signaling#GO:0007267;signaling#GO:0023052;canonical Wnt signaling pathway#GO:0060070;Wnt signaling pathway#GO:0016055 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 intercellular signal molecule#PC00207 Wnt signaling pathway#P00057>Wnt#P01444;Alzheimer disease-presenilin pathway#P00004>Wnt#P00142;Angiogenesis#P00005>Wnt#P00206;Cadherin signaling pathway#P00012>Wnt#P00474 CIOIN|Ensembl=ENSCING00000022981.1|UniProtKB=H2XUA5 H2XUA5 PTHR16171:SF7 DNA REPAIR PROTEIN COMPLEMENTING XP-G CELLS-RELATED DNA REPAIR PROTEIN RAD2 hydrolase activity, acting on ester bonds#GO:0016788;DNA endonuclease activity#GO:0004520;nucleic acid binding#GO:0003676;nuclease activity#GO:0004518;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;single-stranded DNA binding#GO:0003697;DNA binding#GO:0003677;endonuclease activity#GO:0004519;hydrolase activity#GO:0016787;catalytic activity, acting on a nucleic acid#GO:0140640;DNA nuclease activity#GO:0004536;catalytic activity, acting on DNA#GO:0140097 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA metabolism protein#PC00009 CIOIN|Ensembl=ENSCING00000008001.3|UniProtKB=F6VHZ8 F6VHZ8 LOC113474197 PTHR10500:SF0 BETA-MICROSEMINOPROTEIN SCO-SPONDIN-LIKE intercellular signal molecule#PC00207 CIOIN|Ensembl=ENSCING00000024809.1|UniProtKB=H2XTR0 H2XTR0 PTHR24033:SF224 EGF-LIKE DOMAIN-CONTAINING PROTEIN C-TYPE LECTIN CIOIN|Ensembl=ENSCING00000019124.1|UniProtKB=H2XZM3 H2XZM3 PTHR11807:SF12 ATPASES OF THE PP SUPERFAMILY-RELATED CYTOPLASMIC TRNA 2-THIOLATION PROTEIN 1 tRNA binding#GO:0000049;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA modification#GO:0009451;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;tRNA modification#GO:0006400;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;tRNA wobble uridine modification#GO:0002098;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cytosol#GO:0005829;intracellular protein-containing complex#GO:0140535;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000016900.2|UniProtKB=A0A1W2WI04 A0A1W2WI04 LOC100186249 PTHR11710:SF0 40S RIBOSOMAL PROTEIN S19 40S RIBOSOMAL PROTEIN S19 structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;structural molecule activity#GO:0005198;binding#GO:0005488;organic cyclic compound binding#GO:0097159 organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;protein-RNA complex assembly#GO:0022618;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;ribonucleoprotein complex biogenesis#GO:0022613;protein-containing complex assembly#GO:0065003;ribosome biogenesis#GO:0042254;cellular component organization#GO:0016043;protein-RNA complex organization#GO:0071826;non-membrane-bounded organelle assembly#GO:0140694;cellular process#GO:0009987;ribosomal small subunit biogenesis#GO:0042274 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic small ribosomal subunit#GO:0022627;cytosol#GO:0005829;small ribosomal subunit#GO:0015935;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000005938.3|UniProtKB=F6YYW3 F6YYW3 LOC100186999 PTHR15975:SF0 CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 11 CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 11 CCR4-NOT complex#GO:0030014;intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991 CIOIN|Ensembl=ENSCING00000009291.3|UniProtKB=F6TTZ5 F6TTZ5 LOC100176354 PTHR45726:SF3 LEUKOTRIENE A-4 HYDROLASE LEUKOTRIENE A-4 HYDROLASE CIOIN|Ensembl=ENSCING00000022699.1|UniProtKB=H2XRE5 H2XRE5 PTHR24064:SF577 SOLUTE CARRIER FAMILY 22 MEMBER GH09241P secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000006707.3|UniProtKB=F7A8C2 F7A8C2 LOC100186335 PTHR43389:SF4 V-TYPE PROTON ATPASE SUBUNIT B V-TYPE PROTON ATPASE SUBUNIT B ATP synthase#PC00002;primary active transporter#PC00068;transporter#PC00227 CIOIN|Ensembl=ENSCING00000019965.1|UniProtKB=H2XPP3 H2XPP3 PTHR19325:SF560 COMPLEMENT COMPONENT-RELATED SUSHI DOMAIN-CONTAINING SUSHI, VON WILLEBRAND FACTOR TYPE A, EGF AND PENTRAXIN DOMAIN-CONTAINING PROTEIN 1 complement component#PC00078 CIOIN|Ensembl=ENSCING00000011908.2|UniProtKB=F6YX47 F6YX47 PTHR24240:SF223 OPSIN MELATONIN RECEPTOR 1B signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 signal transduction#GO:0007165;response to light stimulus#GO:0009416;cellular response to stimulus#GO:0051716;detection of stimulus#GO:0051606;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;regulation of cellular process#GO:0050794;response to radiation#GO:0009314;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;response to abiotic stimulus#GO:0009628;signaling#GO:0023052;cellular response to light stimulus#GO:0071482 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 CIOIN|Ensembl=ENSCING00000005409.3|UniProtKB=F6Z9S5 F6Z9S5 LOC100178018 PTHR47979:SF33 DRAB11-RELATED DRAB11 GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;anion binding#GO:0043168;ion binding#GO:0043167 localization#GO:0051179;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization#GO:0051234;transport#GO:0006810 cytoplasm#GO:0005737;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular vesicle#GO:0097708;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 small GTPase#PC00208 CIOIN|Ensembl=ENSCING00000016478.2|UniProtKB=F6YNB1 F6YNB1 PTHR21660:SF1 THIOESTERASE SUPERFAMILY MEMBER-RELATED ACYL-COENZYME A THIOESTERASE 13 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;fatty acyl-CoA hydrolase activity#GO:0047617;catalytic activity#GO:0003824;thiolester hydrolase activity#GO:0016790 esterase#PC00097 CIOIN|Ensembl=ENSCING00000001483.3|UniProtKB=F6TI40 F6TI40 LOC100184115 PTHR12560:SF58 LONGEVITY ASSURANCE FACTOR 1 LAG1 CERAMIDE SYNTHASE 1 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity#GO:0003824;N-acyltransferase activity#GO:0016410 lipid metabolic process#GO:0006629;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;membrane lipid biosynthetic process#GO:0046467;sphingolipid metabolic process#GO:0006665;ceramide metabolic process#GO:0006672;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;membrane lipid metabolic process#GO:0006643;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;ceramide biosynthetic process#GO:0046513;cellular lipid metabolic process#GO:0044255;amide metabolic process#GO:0043603;sphingolipid biosynthetic process#GO:0030148;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 transferase#PC00220;metabolite interconversion enzyme#PC00262 TGF-beta signaling pathway#P00052>TGFbeta#P01286 CIOIN|Ensembl=ENSCING00000009747.3|UniProtKB=F7ACB9 F7ACB9 PTHR10153:SF44 SMALL CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNEL SMALL CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNEL PROTEIN monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;potassium ion transmembrane transporter activity#GO:0015079;binding#GO:0005488;calmodulin binding#GO:0005516;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;channel activity#GO:0015267;monoatomic ion-gated channel activity#GO:0022839;calcium-activated potassium channel activity#GO:0015269;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;calcium-activated cation channel activity#GO:0005227;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;ligand-gated monoatomic cation channel activity#GO:0099094;protein binding#GO:0005515;monoatomic ion channel activity#GO:0005216;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion transmembrane transporter activity#GO:0015075;ligand-gated channel activity#GO:0022834 localization#GO:0051179;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;potassium ion transmembrane transport#GO:0071805;monoatomic cation transport#GO:0006812;inorganic ion transmembrane transport#GO:0098660;monoatomic ion transport#GO:0006811;cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;potassium ion transport#GO:0006813 somatodendritic compartment#GO:0036477;cell body#GO:0044297;neuron projection#GO:0043005;neuronal cell body#GO:0043025;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227;voltage-gated ion channel#PC00241 CIOIN|Ensembl=ENSCING00000007517.3|UniProtKB=F6TWF6 F6TWF6 LOC100184485 PTHR43521:SF1 ALPHA-AMINOADIPIC SEMIALDEHYDE DEHYDROGENASE ALPHA-AMINOADIPIC SEMIALDEHYDE DEHYDROGENASE dehydrogenase#PC00092;oxidoreductase#PC00176 5-Hydroxytryptamine degredation#P04372>Aldehyde Dehydrogenase#P04402 CIOIN|Ensembl=ENSCING00000003777.3|UniProtKB=F6TIL4 F6TIL4 bmp5_7-like PTHR11848:SF310 TGF-BETA FAMILY PROTEIN 60A-RELATED molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;cytokine activity#GO:0005125;protein binding#GO:0005515;signaling receptor binding#GO:0005102 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 DPP-SCW signaling pathway#P06212>SCW full length#P06275;BMP/activin signaling pathway-drosophila#P06211>Full-length BMP orthologous ligand#P06256;TGF-beta signaling pathway#P00052>TGFbeta#P01286;GBB signaling pathway#P06214>GBB#P06294;DPP-SCW signaling pathway#P06212>SCW#P06259;SCW signaling pathway#P06216>SCW#P06326;SCW signaling pathway#P06216>SCW full length#P06322;BMP/activin signaling pathway-drosophila#P06211>BMP/activin orthologous ligand#P06251 CIOIN|Ensembl=ENSCING00000018562.1|UniProtKB=H2XW76 H2XW76 PTHR10221:SF9 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 6 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 6 transcription coactivator activity#GO:0003713;molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;protein-macromolecule adaptor activity#GO:0030674 cellular aromatic compound metabolic process#GO:0006725;DNA-templated transcription#GO:0006351;cellular component biogenesis#GO:0044085;protein-DNA complex organization#GO:0071824;RNA metabolic process#GO:0016070;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;protein-DNA complex assembly#GO:0065004;nucleobase-containing compound metabolic process#GO:0006139;RNA polymerase II preinitiation complex assembly#GO:0051123;transcription initiation at RNA polymerase II promoter#GO:0006367;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;DNA-templated transcription initiation#GO:0006352;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular component assembly#GO:0022607;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;protein-containing complex organization#GO:0043933;aromatic compound biosynthetic process#GO:0019438;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;DNA-directed RNA polymerase complex#GO:0000428;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nucleoplasm#GO:0005654;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;transcription factor TFIID complex#GO:0005669;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622;RNA polymerase II, holoenzyme#GO:0016591;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;transcription regulator complex#GO:0005667;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 general transcription factor#PC00259 General transcription regulation#P00023>TBP-associated factors#P00658;General transcription regulation#P00023>TBP#P00670;Transcription regulation by bZIP transcription factor#P00055>TBP-associated factors#P01385 CIOIN|Ensembl=ENSCING00000000048.3|UniProtKB=F6VUI1 F6VUI1 LOC100181380 PTHR46374:SF1 PROTEIN CBG07384 START DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000007550.3|UniProtKB=F6T8C7 F6T8C7 LOC100184134 PTHR11937:SF387 ACTIN ACTIN-LIKE PROTEIN 53D intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 actin and actin related protein#PC00039;cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 Wnt signaling pathway#P00057>NFAT Target Genes#G01559;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>F-actin#P00858;Alzheimer disease-presenilin pathway#P00004>actin#P00114;Integrin signalling pathway#P00034>Actin#P00944;Huntington disease#P00029>Actin#P00807;Nicotinic acetylcholine receptor signaling pathway#P00044>Actin#P01090;Cadherin signaling pathway#P00012>F-actin#P00470;Cytoskeletal regulation by Rho GTPase#P00016>Actin#P00512 CIOIN|Ensembl=ENSCING00000013489.2|UniProtKB=F7BK77 F7BK77 PTHR45153:SF1 TETRATRICOPEPTIDE REPEAT PROTEIN 16 TETRATRICOPEPTIDE REPEAT PROTEIN 16 CIOIN|Ensembl=ENSCING00000023444.1|UniProtKB=H2Y2U7 H2Y2U7 PTHR33631:SF1 FAMILY NOT NAMED DYNEIN HEAVY CHAIN CIOIN|Ensembl=ENSCING00000021225.1|UniProtKB=H2Y0J5 H2Y0J5 PTHR11537:SF254 VOLTAGE-GATED POTASSIUM CHANNEL POTASSIUM VOLTAGE-GATED CHANNEL PROTEIN SHAB monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated potassium channel activity#GO:0005249;channel activity#GO:0015267;transporter activity#GO:0005215;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;regulation of membrane potential#GO:0042391;action potential#GO:0001508;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;localization#GO:0051179;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;monoatomic cation transport#GO:0006812;potassium ion transmembrane transport#GO:0071805;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;potassium ion transport#GO:0006813 cellular anatomical entity#GO:0110165;membrane#GO:0016020 transporter#PC00227;voltage-gated ion channel#PC00241 CIOIN|Ensembl=ENSCING00000008478.3|UniProtKB=F6T453 F6T453 PTHR10177:SF593 CYCLINS G2_MITOTIC-SPECIFIC CYCLIN-A protein kinase regulator activity#GO:0019887;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207 regulation of protein kinase activity#GO:0045859;regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;mitotic cell cycle phase transition#GO:0044772;regulation of nitrogen compound metabolic process#GO:0051171;cell cycle process#GO:0022402;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;cell cycle phase transition#GO:0044770;mitotic cell cycle process#GO:1903047;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;regulation of primary metabolic process#GO:0080090;mitotic cell cycle#GO:0000278;regulation of macromolecule metabolic process#GO:0060255;regulation of molecular function#GO:0065009;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;regulation of protein serine/threonine kinase activity#GO:0071900;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cyclin-dependent protein serine/threonine kinase activity#GO:0000079;regulation of kinase activity#GO:0043549;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;protein kinase complex#GO:1902911;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622 kinase activator#PC00138 CIOIN|Ensembl=ENSCING00000023529.1|UniProtKB=H2Y0K0 H2Y0K0 PTHR31699:SF1 NUDIX T16 FAMILY MEMBER U8 SNORNA-DECAPPING ENZYME snoRNA binding#GO:0030515;catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;nuclease activity#GO:0004518;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;endonuclease activity#GO:0004519;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity#GO:0016787;RNA nuclease activity#GO:0004540;RNA endonuclease activity#GO:0004521 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;heterocycle catabolic process#GO:0046700;RNA metabolic process#GO:0016070;nucleobase-containing compound metabolic process#GO:0006139;cellular nitrogen compound catabolic process#GO:0044270;regulation of biological process#GO:0050789;ncRNA metabolic process#GO:0034660;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;mRNA catabolic process#GO:0006402;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance catabolic process#GO:1901575;negative regulation of cellular process#GO:0048523;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;negative regulation of biosynthetic process#GO:0009890;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;nucleobase-containing compound catabolic process#GO:0034655;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000015057.2|UniProtKB=F6S817 F6S817 PTHR21847:SF1 EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 10 EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 10 calmodulin-related#PC00061 CIOIN|Ensembl=ENSCING00000012684.2|UniProtKB=F6U3H6 F6U3H6 PTHR11949:SF53 INTERFERON REGULATORY FACTOR IRF TRYPTOPHAN PENTAD REPEAT DOMAIN-CONTAINING PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 CIOIN|Ensembl=ENSCING00000024382.1|UniProtKB=H2XM66 H2XM66 PTHR23163:SF0 RING FINGER PROTEIN-RELATED E3 UBIQUITIN-PROTEIN LIGASE BRE1 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-DNA complex#GO:0032993;chromatin#GO:0000785;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227 CIOIN|Ensembl=ENSCING00000008607.3|UniProtKB=F6TNY6 F6TNY6 thbsbi PTHR10199:SF100 THROMBOSPONDIN THROMBOSPONDIN, ISOFORM A external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165 cell adhesion molecule#PC00069 CIOIN|Ensembl=ENSCING00000025115.1|UniProtKB=H2Y2J7 H2Y2J7 PTHR11339:SF373 EXTRACELLULAR MATRIX GLYCOPROTEIN RELATED VWFD DOMAIN-CONTAINING PROTEIN external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 extracellular matrix protein#PC00102 CIOIN|Ensembl=ENSCING00000022878.1|UniProtKB=H2Y256 H2Y256 PTHR24111:SF0 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 34 LEUCINE-RICH REPEAT-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000009511.3|UniProtKB=F6XJ27 F6XJ27 PTHR46473:SF10 GH08155P LD45603P-RELATED CIOIN|Ensembl=ENSCING00000025034.1|UniProtKB=H2XR40 H2XR40 PTHR12183:SF32 MITOCHONDRIAL UBIQUITIN LIGASE ACTIVATOR OF NFKB 1 MITOCHONDRIAL E3 UBIQUITIN PROTEIN LIGASE 1 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 CIOIN|Ensembl=ENSCING00000002252.3|UniProtKB=F6W2W3 F6W2W3 PTHR31735:SF1 VACUOLAR MEMBRANE PROTEIN YPL162C VACUOLAR MEMBRANE PROTEIN YPL162C cellular anatomical entity#GO:0110165;membrane#GO:0016020 CIOIN|Ensembl=ENSCING00000002196.3|UniProtKB=F6S4C0 F6S4C0 LOC100179044 PTHR12473:SF17 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE MINDY-4-RELATED UBIQUITIN CARBOXYL-TERMINAL HYDROLASE MINDY-3 hydrolase activity#GO:0016787;ubiquitin-like protein peptidase activity#GO:0019783;deubiquitinase activity#GO:0101005;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 CIOIN|Ensembl=ENSCING00000007423.3|UniProtKB=F7AP89 F7AP89 PTHR11347:SF219 CYCLIC NUCLEOTIDE PHOSPHODIESTERASE CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE, ISOFORM I hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;cyclic-nucleotide phosphodiesterase activity#GO:0004112;phosphoric diester hydrolase activity#GO:0008081;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;cellular process#GO:0009987;cAMP-mediated signaling#GO:0019933;signaling#GO:0023052;cyclic-nucleotide-mediated signaling#GO:0019935 phosphodiesterase#PC00185 CIOIN|Ensembl=ENSCING00000020883.1|UniProtKB=H2XU85 H2XU85 PTHR22168:SF7 TMEM26 PROTEIN TRANSMEMBRANE PROTEIN 26-LIKE CIOIN|Ensembl=ENSCING00000023737.1|UniProtKB=A0A1W5BFH2 A0A1W5BFH2 LOC100179969 PTHR24347:SF393 SERINE/THREONINE-PROTEIN KINASE SPAGHETTI-SQUASH ACTIVATOR, ISOFORM C transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>MLCK#P00877;Cytoskeletal regulation by Rho GTPase#P00016>MLCK#P00514 CIOIN|Ensembl=ENSCING00000019150.1|UniProtKB=Q1RLF5 Q1RLF5 Ci-ZF(C2H2)-78 PTHR23235:SF164 KRUEPPEL-LIKE TRANSCRIPTION FACTOR C2H2-TYPE DOMAIN-CONTAINING PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 CIOIN|Ensembl=ENSCING00000021864.1|UniProtKB=H2XT68 H2XT68 PTHR21490:SF2 ENKURIN-RELATED ENKURIN DOMAIN-CONTAINING PROTEIN 1 supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;cytoplasmic microtubule#GO:0005881;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000003924.3|UniProtKB=F7A581 F7A581 PTHR22762:SF131 ALPHA-GLUCOSIDASE GLYCOSIDE HYDROLASE FAMILY 31 N-TERMINAL DOMAIN-CONTAINING PROTEIN hydrolase activity#GO:0016787;glucosidase activity#GO:0015926;hydrolase activity, acting on glycosyl bonds#GO:0016798;alpha-glucosidase activity#GO:0090599;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 glucosidase#PC00108;metabolite interconversion enzyme#PC00262;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000018121.1|UniProtKB=H2XX79 H2XX79 PTHR13869:SF24 MYELIN P0 RELATED BASEMENT MEMBRANE-SPECIFIC HEPARAN SULFATE PROTEOGLYCAN CORE PROTEIN-LIKE myelin protein#PC00161;structural protein#PC00211 CIOIN|Ensembl=ENSCING00000019804.1|UniProtKB=H2XXM8 H2XXM8 PTHR22906:SF43 PROPERDIN PROPERDIN CIOIN|Ensembl=ENSCING00000010089.3|UniProtKB=F6PIU4 F6PIU4 LOC100182174 PTHR14002:SF20 ENDOGLIN/TGF-BETA RECEPTOR TYPE III ZONA PELLUCIDA-LIKE DOMAIN-CONTAINING PROTEIN 1 transmembrane signal receptor#PC00197 CIOIN|Ensembl=ENSCING00000000846.3|UniProtKB=A2SY09 A2SY09 act PTHR11937:SF571 ACTIN ACTIN, CYTOSKELETAL 1B actin and actin related protein#PC00039;cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 Integrin signalling pathway#P00034>Actin#P00944;Alzheimer disease-presenilin pathway#P00004>actin#P00114;Nicotinic acetylcholine receptor signaling pathway#P00044>Actin#P01090;Huntington disease#P00029>Actin#P00807;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>F-actin#P00858;Cadherin signaling pathway#P00012>F-actin#P00470;Cytoskeletal regulation by Rho GTPase#P00016>Actin#P00512 CIOIN|Ensembl=ENSCING00000024092.1|UniProtKB=H2XLI4 H2XLI4 PTHR24096:SF149 LONG-CHAIN-FATTY-ACID--COA LIGASE AMP-BINDING DOMAIN-CONTAINING PROTEIN-RELATED ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877 metabolite interconversion enzyme#PC00262;ligase#PC00142 CIOIN|Ensembl=ENSCING00000020616.1|UniProtKB=H2XQP9 H2XQP9 PTHR21501:SF1 PROTEIN FAM-161 PROTEIN FAM-161 cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782;cellular component organization#GO:0016043;cellular process#GO:0009987;cell projection organization#GO:0030030;plasma membrane bounded cell projection organization#GO:0120036;organelle organization#GO:0006996 membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;cilium#GO:0005929;organelle#GO:0043226 CIOIN|Ensembl=ENSCING00000002371.3|UniProtKB=A0A1W2W7W2 A0A1W2W7W2 LOC100182268 PTHR13407:SF0 RNF121 PROTEIN FI05221P transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 response to organic substance#GO:0010033;macromolecule catabolic process#GO:0009057;cellular response to stimulus#GO:0051716;response to endoplasmic reticulum stress#GO:0034976;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;response to organonitrogen compound#GO:0010243;ERAD pathway#GO:0036503;cellular process#GO:0009987;primary metabolic process#GO:0044238;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;cellular response to stress#GO:0033554;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;Golgi membrane#GO:0000139;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000001592.3|UniProtKB=F6VBR9 F6VBR9 PTHR13593:SF113 FAMILY NOT NAMED SI:DKEY-266F7.9 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphoric diester hydrolase activity#GO:0008081;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 CIOIN|Ensembl=ENSCING00000021702.1|UniProtKB=H2XPD5 H2XPD5 PTHR46282:SF2 LEUCINE-RICH MELANOCYTE DIFFERENTIATION-ASSOCIATED PROTEIN LEUCINE-RICH MELANOCYTE DIFFERENTIATION-ASSOCIATED PROTEIN pigmentation#GO:0043473;cellular developmental process#GO:0048869;cell differentiation#GO:0030154;developmental pigmentation#GO:0048066;cellular process#GO:0009987;melanocyte differentiation#GO:0030318;developmental process#GO:0032502 CIOIN|Ensembl=ENSCING00000011538.2|UniProtKB=A0A1W2WHY7 A0A1W2WHY7 LOC100180716 PTHR10956:SF0 60S RIBOSOMAL PROTEIN L31 60S RIBOSOMAL PROTEIN L31 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cytoplasmic translation#GO:0002181;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic large ribosomal subunit#GO:0022625;large ribosomal subunit#GO:0015934;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000007466.3|UniProtKB=F6YIH8 F6YIH8 LOC100182198 PTHR19378:SF0 GOLGIN- RELATED HAUS AUGMIN-LIKE COMPLEX SUBUNIT 3 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;cellular component organization#GO:0016043;cellular process#GO:0009987;microtubule organizing center organization#GO:0031023;chromosome segregation#GO:0007059;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;spindle assembly#GO:0051225;cytoskeleton organization#GO:0007010;cell cycle#GO:0007049;spindle organization#GO:0007051;non-membrane-bounded organelle assembly#GO:0140694 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;mitotic spindle#GO:0072686;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;spindle#GO:0005819;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000015930.2|UniProtKB=Q4H3F5 Q4H3F5 Ci-GATA-b PTHR10071:SF337 TRANSCRIPTION FACTOR GATA FAMILY MEMBER GATA-BINDING FACTOR A sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of nitrogen compound metabolic process#GO:0051173;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;positive regulation of RNA biosynthetic process#GO:1902680;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;positive regulation of biological process#GO:0048518;negative regulation of cellular process#GO:0048523;cellular developmental process#GO:0048869;negative regulation of biosynthetic process#GO:0009890;regulation of DNA-templated transcription#GO:0006355;negative regulation of metabolic process#GO:0009892;positive regulation of cellular biosynthetic process#GO:0031328;cell fate commitment#GO:0045165;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;negative regulation of nitrogen compound metabolic process#GO:0051172;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;positive regulation of RNA metabolic process#GO:0051254;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218 CIOIN|Ensembl=ENSCING00000015182.2|UniProtKB=A0A1W2W0N1 A0A1W2W0N1 LOC100186253 PTHR10556:SF57 3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE 3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE 1 oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 lipid metabolic process#GO:0006629;steroid metabolic process#GO:0008202;organic cyclic compound metabolic process#GO:1901360;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;lipid biosynthetic process#GO:0008610;steroid biosynthetic process#GO:0006694;metabolic process#GO:0008152;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704 dehydrogenase#PC00092;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000000576.3|UniProtKB=F6Q3E6 F6Q3E6 PTHR13890:SF0 RNA SPLICING PROTEIN MRS2, MITOCHONDRIAL MAGNESIUM TRANSPORTER MRS2 HOMOLOG, MITOCHONDRIAL inorganic molecular entity transmembrane transporter activity#GO:0015318;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;inorganic cation transmembrane transporter activity#GO:0022890;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075 localization#GO:0051179;monoatomic cation transport#GO:0006812;metal ion transport#GO:0030001;monoatomic ion transport#GO:0006811;establishment of localization#GO:0051234;transport#GO:0006810 RNA splicing factor#PC00148;RNA processing factor#PC00147;RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000024891.1|UniProtKB=H2XS49 H2XS49 PTHR44942:SF4 METHYLTRANSF_11 DOMAIN-CONTAINING PROTEIN METHYLTRANSFERASE TYPE 11 DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000008162.3|UniProtKB=F6Y4C9 F6Y4C9 tnfa PTHR11471:SF13 TUMOR NECROSIS FACTOR FAMILY MEMBER TNF FAMILY PROFILE DOMAIN-CONTAINING PROTEIN intercellular signal molecule#PC00207 CIOIN|Ensembl=ENSCING00000011642.2|UniProtKB=F7A5W3 F7A5W3 PTHR10231:SF36 NUCLEOTIDE-SUGAR TRANSMEMBRANE TRANSPORTER UDP-N-ACETYLGLUCOSAMINE TRANSPORTER transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 localization#GO:0051179;cellular process#GO:0009987;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810 cytoplasm#GO:0005737;bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;Golgi membrane#GO:0000139;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transporter#PC00227 CIOIN|Ensembl=ENSCING00000003373.3|UniProtKB=F6TNN0 F6TNN0 nf-e2 PTHR24411:SF55 NUCLEAR FACTOR ERYTHROID 2-RELATED FACTOR SEGMENTATION PROTEIN CAP'N'COLLAR sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;basic leucine zipper transcription factor#PC00056 CIOIN|Ensembl=ENSCING00000000337.3|UniProtKB=F6QQ49 F6QQ49 PTHR11223:SF3 EXPORTIN 1/5 EXPORTIN-5 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular localization#GO:0051641;macromolecule localization#GO:0033036;establishment of RNA localization#GO:0051236;transport#GO:0006810;nucleic acid transport#GO:0050657;nitrogen compound transport#GO:0071705;cellular process#GO:0009987;RNA localization#GO:0006403;localization#GO:0051179;organic substance transport#GO:0071702;nuclear export#GO:0051168;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;RNA transport#GO:0050658;nucleobase-containing compound transport#GO:0015931;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;nuclear transport#GO:0051169 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transporter#PC00227 CIOIN|Ensembl=ENSCING00000022306.1|UniProtKB=F7AC12 F7AC12 PTHR23192:SF85 OLFACTOMEDIN-RELATED GLIOMEDIN regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 structural protein#PC00211 CIOIN|Ensembl=ENSCING00000001150.3|UniProtKB=F6YU96 F6YU96 LOC100175699 PTHR10367:SF17 MRNA-CAPPING ENZYME MRNA-CAPPING ENZYME catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on RNA#GO:0140098;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;mRNA processing#GO:0006397;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 RNA processing factor#PC00147;RNA metabolism protein#PC00031;mRNA capping factor#PC00145 CIOIN|Ensembl=ENSCING00000020758.1|UniProtKB=H2XN62 H2XN62 PTHR20905:SF1 N-ACETYLTRANSFERASE-RELATED AT07410P-RELATED acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;N-acetyltransferase activity#GO:0008080;acyltransferase activity#GO:0016746;acetyltransferase activity#GO:0016407;catalytic activity#GO:0003824;N-acyltransferase activity#GO:0016410 acetyltransferase#PC00038 CIOIN|Ensembl=ENSCING00000001700.3|UniProtKB=F6UJQ6 F6UJQ6 PTHR24320:SF282 RETINOL DEHYDROGENASE WW DOMAIN-CONTAINING OXIDOREDUCTASE dehydrogenase#PC00092;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000001431.3|UniProtKB=H2XY50 H2XY50 LOC100181170 PTHR16165:SF5 NXPE FAMILY MEMBER NXPE FAMILY MEMBER 3 CIOIN|Ensembl=ENSCING00000000609.3|UniProtKB=Q1RLF1 Q1RLF1 Ci-ZF(C2H2)-81 PTHR24381:SF393 ZINC FINGER PROTEIN CHROMATIN-LINKED ADAPTOR FOR MSL PROTEINS, ISOFORM B sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 CIOIN|Ensembl=ENSCING00000000204.4|UniProtKB=F6WF19 F6WF19 LOC100181214 PTHR11384:SF62 ATP-BINDING CASSETTE, SUB-FAMILY D MEMBER ATP-BINDING CASSETTE SUB-FAMILY D MEMBER 3 carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;ATPase-coupled transmembrane transporter activity#GO:0042626;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;lipid transporter activity#GO:0005319;transmembrane transporter activity#GO:0022857;primary active transmembrane transporter activity#GO:0015399;ATP-dependent activity#GO:0140657;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167;ATP binding#GO:0005524 lipid metabolic process#GO:0006629;monocarboxylic acid transport#GO:0015718;cellular localization#GO:0051641;macromolecule localization#GO:0033036;organic acid transport#GO:0015849;fatty acid transport#GO:0015908;transport#GO:0006810;lipid catabolic process#GO:0016042;lipid modification#GO:0030258;lipid transport#GO:0006869;carboxylic acid transmembrane transport#GO:1905039;organic substance transport#GO:0071702;establishment of localization#GO:0051234;fatty acid beta-oxidation#GO:0006635;catabolic process#GO:0009056;lipid localization#GO:0010876;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;cellular lipid catabolic process#GO:0044242;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;intracellular lipid transport#GO:0032365;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;transmembrane transport#GO:0055085;organic anion transport#GO:0015711;cellular metabolic process#GO:0044237;carboxylic acid transport#GO:0046942;lipid oxidation#GO:0034440;cellular component organization#GO:0016043;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;fatty acid catabolic process#GO:0009062;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic acid catabolic process#GO:0016054;fatty acid metabolic process#GO:0006631;small molecule catabolic process#GO:0044282;organelle organization#GO:0006996;establishment of localization in cell#GO:0051649;organic acid transmembrane transport#GO:1903825;intracellular transport#GO:0046907;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;peroxisome organization#GO:0007031;long-chain fatty acid transport#GO:0015909;monocarboxylic acid catabolic process#GO:0072329;small molecule metabolic process#GO:0044281 bounding membrane of organelle#GO:0098588;peroxisomal membrane#GO:0005778;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;peroxisome#GO:0005777;microbody#GO:0042579;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ATP-binding cassette (ABC) transporter#PC00003;transporter#PC00227 CIOIN|Ensembl=ENSCING00000007572.3|UniProtKB=F7AMB1 F7AMB1 LOC100178879 PTHR19444:SF13 UNC-93 RELATED PROTEIN UNC-93 HOMOLOG A membrane-bound signaling molecule#PC00152 CIOIN|Ensembl=ENSCING00000013583.2|UniProtKB=Q4H3L7 Q4H3L7 Ci-ERF1 PTHR11849:SF59 ETS ETS DOMAIN-CONTAINING PROTEIN transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 CIOIN|Ensembl=ENSCING00000002389.3|UniProtKB=F6QCF9 F6QCF9 PTHR10037:SF288 VOLTAGE-GATED CATION CHANNEL CALCIUM AND SODIUM SODIUM CHANNEL PROTEIN PARA monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;sodium channel activity#GO:0005272;monoatomic cation transmembrane transporter activity#GO:0008324;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;channel activity#GO:0015267;monoatomic ion channel activity#GO:0005216;inorganic cation transmembrane transporter activity#GO:0022890 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;membrane depolarization#GO:0051899;transport#GO:0006810;regulation of membrane potential#GO:0042391;system process#GO:0003008;action potential#GO:0001508;nervous system process#GO:0050877;cell communication#GO:0007154;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;localization#GO:0051179;sodium ion transport#GO:0006814;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;monoatomic cation transport#GO:0006812;multicellular organismal process#GO:0032501;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;sodium ion transmembrane transport#GO:0035725 membrane protein complex#GO:0098796;sodium channel complex#GO:0034706;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;cation channel complex#GO:0034703;plasma membrane#GO:0005886 transporter#PC00227;voltage-gated ion channel#PC00241 CIOIN|Ensembl=ENSCING00000006869.3|UniProtKB=F6ZCS4 F6ZCS4 PTHR11215:SF1 METAL DEPENDENT HYDROLASE - RELATED MYG1 EXONUCLEASE metabolite interconversion enzyme#PC00262;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000005335.3|UniProtKB=F7B5B2 F7B5B2 LOC100179626 PTHR10309:SF0 MANNOSE-6-PHOSPHATE ISOMERASE MANNOSE-6-PHOSPHATE ISOMERASE isomerase activity#GO:0016853;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;carbohydrate derivative metabolic process#GO:1901135;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleotide-sugar metabolic process#GO:0009225;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;organic cyclic compound metabolic process#GO:1901360;nucleobase-containing compound biosynthetic process#GO:0034654;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;aromatic compound biosynthetic process#GO:0019438;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 isomerase#PC00135;metabolite interconversion enzyme#PC00262 Mannose metabolism#P02752>Mannose 6-P isomerase#P03017 CIOIN|Ensembl=ENSCING00000021899.1|UniProtKB=A0A1W2WJE4 A0A1W2WJE4 LOC100185578 PTHR11586:SF33 TRNA-AMINOACYLATION COFACTOR ARC1 FAMILY MEMBER AMINOACYL TRNA SYNTHASE COMPLEX-INTERACTING MULTIFUNCTIONAL PROTEIN 1 translational protein#PC00263 CIOIN|Ensembl=ENSCING00000000489.3|UniProtKB=F6YCK1 F6YCK1 LOC100180202 PTHR24412:SF172 KELCH PROTEIN KELCH-LIKE PROTEIN 10 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000022854.1|UniProtKB=H2XQ58 H2XQ58 LOC104266305 PTHR12241:SF154 TUBULIN POLYGLUTAMYLASE TUBULIN POLYGLUTAMYLASE TTLL11 cytoskeletal protein binding#GO:0008092;ligase activity#GO:0016874;protein binding#GO:0005515;tubulin binding#GO:0015631;catalytic activity, acting on a protein#GO:0140096;binding#GO:0005488;catalytic activity#GO:0003824 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;microtubule cytoskeleton organization#GO:0000226;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;cellular component organization#GO:0016043;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;nitrogen compound metabolic process#GO:0006807;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;microtubule cytoskeleton#GO:0015630;ciliary basal body#GO:0036064;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;cilium#GO:0005929;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;microtubule or microtubule-binding cytoskeletal protein#PC00157 CIOIN|Ensembl=ENSCING00000006261.3|UniProtKB=F6V1Q0 F6V1Q0 PTHR11878:SF65 SODIUM/CALCIUM EXCHANGER NA_CA-EXCHANGE PROTEIN, ISOFORM G localization#GO:0051179;monoatomic cation transport#GO:0006812;metal ion transport#GO:0030001;establishment of localization#GO:0051234;monoatomic ion transport#GO:0006811;transport#GO:0006810 cellular anatomical entity#GO:0110165;membrane#GO:0016020 secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000016175.2|UniProtKB=A0A1W5BEV8 A0A1W5BEV8 LOC100185260 PTHR31158:SF1 DUAL OXIDASE 2 DOXA1 FACTOR-RELATED cellular anatomical entity#GO:0110165;membrane#GO:0016020 oxidase#PC00175;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000015973.2|UniProtKB=F6WHY6 F6WHY6 PTHR21399:SF0 CHLORIDE CONDUCTANCE REGULATORY PROTEIN ICLN METHYLOSOME SUBUNIT PICLN cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;RNA processing#GO:0006396;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;mRNA cis splicing, via spliceosome#GO:0045292;protein-RNA complex assembly#GO:0022618;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;spliceosomal snRNP assembly#GO:0000387;organic substance metabolic process#GO:0071704;mRNA splicing, via spliceosome#GO:0000398;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;protein-containing complex organization#GO:0043933;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;ribonucleoprotein complex biogenesis#GO:0022613;mRNA processing#GO:0006397;protein-RNA complex organization#GO:0071826;RNA splicing, via transesterification reactions#GO:0000375 cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;pICln-Sm protein complex#GO:0034715;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;Sm-like protein family complex#GO:0120114;spliceosomal complex#GO:0005681;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transporter#PC00227 CIOIN|Ensembl=ENSCING00000004111.4|UniProtKB=F6XUS6 F6XUS6 PTHR48083:SF35 MEDIUM-CHAIN SPECIFIC ACYL-COA DEHYDROGENASE, MITOCHONDRIAL-RELATED ACYL-COA DEHYDROGENASE FAMILY MEMBER 10 oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;lipid oxidation#GO:0034440;cellular metabolic process#GO:0044237;lipid catabolic process#GO:0016042;lipid modification#GO:0030258;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;fatty acid catabolic process#GO:0009062;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;fatty acid metabolic process#GO:0006631;small molecule catabolic process#GO:0044282;fatty acid beta-oxidation#GO:0006635;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;cellular lipid metabolic process#GO:0044255;cellular lipid catabolic process#GO:0044242;carboxylic acid metabolic process#GO:0019752;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;monocarboxylic acid catabolic process#GO:0072329 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 dehydrogenase#PC00092;oxidoreductase#PC00176 5-Hydroxytryptamine degredation#P04372>Aldehyde Dehydrogenase#P04402 CIOIN|Ensembl=ENSCING00000004104.3|UniProtKB=F6YGZ1 F6YGZ1 PTHR19879:SF1 TRANSCRIPTION INITIATION FACTOR TFIID CANNONBALL-RELATED cellular aromatic compound metabolic process#GO:0006725;DNA-templated transcription#GO:0006351;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;RNA biosynthetic process#GO:0032774;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;transcription initiation at RNA polymerase II promoter#GO:0006367;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nucleobase-containing compound biosynthetic process#GO:0034654;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;DNA-templated transcription initiation#GO:0006352;aromatic compound biosynthetic process#GO:0019438;transcription by RNA polymerase II#GO:0006366;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;DNA-directed RNA polymerase complex#GO:0000428;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;transcription factor TFIID complex#GO:0005669;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695;RNA polymerase II, holoenzyme#GO:0016591;RNA polymerase complex#GO:0030880;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 CIOIN|Ensembl=ENSCING00000000382.3|UniProtKB=F6SF69 F6SF69 LOC100177471 PTHR22760:SF1 GLYCOSYLTRANSFERASE DOL-P-MAN:MAN(7)GLCNAC(2)-PP-DOL ALPHA-1,6-MANNOSYLTRANSFERASE mannosyltransferase activity#GO:0000030;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein N-linked glycosylation#GO:0006487;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000023424.1|UniProtKB=H2XZG6 H2XZG6 PTHR10157:SF23 DOPAMINE BETA HYDROXYLASE RELATED MOXD1 HOMOLOG 1 hydroxylase#PC00122 CIOIN|Ensembl=ENSCING00000007462.3|UniProtKB=F6YIR3 F6YIR3 PTHR12461:SF105 HYPOXIA-INDUCIBLE FACTOR 1 ALPHA INHIBITOR-RELATED HYPOXIA-INDUCIBLE FACTOR 1-ALPHA INHIBITOR protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000003728.3|UniProtKB=L7N0R6 L7N0R6 LOC100179867 PTHR11119:SF3 XANTHINE-URACIL / VITAMIN C PERMEASE FAMILY MEMBER LD30822P transporter#PC00227 CIOIN|Ensembl=ENSCING00000014785.2|UniProtKB=F6VLL9 F6VLL9 PTHR24412:SF497 KELCH PROTEIN KELCH-LIKE PROTEIN 18 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000003483.3|UniProtKB=F6UA38 F6UA38 PTHR13484:SF0 FIP1-LIKE 1 PROTEIN PRE-MRNA 3'-END-PROCESSING FACTOR FIP1 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;mRNA cleavage factor complex#GO:0005849;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;mRNA cleavage and polyadenylation specificity factor complex#GO:0005847;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000001027.3|UniProtKB=F6W0L7 F6W0L7 LOC100185619 PTHR22588:SF3 VWFA DOMAIN-CONTAINING PROTEIN VWFA DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000018214.1|UniProtKB=H2XMP8 H2XMP8 PTHR36978:SF4 P-LOOP CONTAINING NUCLEOTIDE TRIPHOSPHATE HYDROLASE P-LOOP CONTAINING NUCLEOSIDE TRIPHOSPHATE HYDROLASE PROTEIN metabolite interconversion enzyme#PC00262;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000015473.2|UniProtKB=F6VC11 F6VC11 PTHR14513:SF0 PROTECTION OF TELOMERES 1 PROTECTION OF TELOMERES PROTEIN 1 sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;single-stranded telomeric DNA binding#GO:0043047;molecular function regulator activity#GO:0098772;single-stranded DNA binding#GO:0003697;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;telomeric DNA binding#GO:0042162;enzyme inhibitor activity#GO:0004857;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234 cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of nitrogen compound metabolic process#GO:0051171;telomere organization#GO:0032200;regulation of DNA metabolic process#GO:0051052;regulation of cellular component organization#GO:0051128;regulation of telomere maintenance#GO:0032204;regulation of catalytic activity#GO:0050790;nucleobase-containing compound metabolic process#GO:0006139;telomere maintenance#GO:0000723;regulation of biological process#GO:0050789;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;regulation of molecular function#GO:0065009;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA metabolic process#GO:0051053;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of chromosome organization#GO:0033044;heterocycle metabolic process#GO:0046483;negative regulation of biosynthetic process#GO:0009890;telomere capping#GO:0016233;macromolecule metabolic process#GO:0043170;regulation of organelle organization#GO:0033043;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of transferase activity#GO:0051338;negative regulation of catalytic activity#GO:0043086;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;negative regulation of molecular function#GO:0044092;DNA metabolic process#GO:0006259 nuclear telomere cap complex#GO:0000783;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-DNA complex#GO:0032993;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome, telomeric region#GO:0000781;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;chromosomal region#GO:0098687;nuclear protein-containing complex#GO:0140513 DNA metabolism protein#PC00009 CIOIN|Ensembl=ENSCING00000020289.1|UniProtKB=H2XTD1 H2XTD1 LOC100175402 PTHR24024:SF18 PULMONARY SURFACTANT-ASSOCIATED PROTEIN A SHORT-CHAIN COLLAGEN C4-LIKE extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 surfactant#PC00212;structural protein#PC00211 CIOIN|Ensembl=ENSCING00000014698.2|UniProtKB=F6ZCF4 F6ZCF4 LOC100178784 PTHR11735:SF6 TRNA N6-ADENOSINE THREONYLCARBAMOYLTRANSFERASE TRNA N6-ADENOSINE THREONYLCARBAMOYLTRANSFERASE, MITOCHONDRIAL RNA processing factor#PC00147 CIOIN|Ensembl=ENSCING00000020741.1|UniProtKB=H2XQA6 H2XQA6 LOC100175950 PTHR31449:SF3 UPF0598 PROTEIN C8ORF82 UPF0598 PROTEIN C8ORF82 CIOIN|Ensembl=ENSCING00000023149.1|UniProtKB=Q2PEE1 Q2PEE1 Ci-LC6 PTHR11886:SF35 DYNEIN LIGHT CHAIN DYNEIN LIGHT CHAIN protein binding#GO:0005515;binding#GO:0005488 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;microtubule cytoskeleton#GO:0015630;dynein complex#GO:0030286;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic dynein complex#GO:0005868;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;microtubule or microtubule-binding cytoskeletal protein#PC00157 Huntington disease#P00029>Dynein complex#P00774 CIOIN|Ensembl=ENSCING00000002130.3|UniProtKB=F6WRK8 F6WRK8 PTHR13140:SF706 MYOSIN DILUTE CLASS UNCONVENTIONAL MYOSIN, ISOFORM C microfilament motor activity#GO:0000146;cytoskeletal protein binding#GO:0008092;ATP-dependent activity#GO:0140657;binding#GO:0005488;actin filament binding#GO:0051015;cytoskeletal motor activity#GO:0003774;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779 cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;membrane#GO:0016020;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 actin binding motor protein#PC00040 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 CIOIN|Ensembl=ENSCING00000003298.3|UniProtKB=F6W1X7 F6W1X7 PTHR11645:SF62 PYRROLINE-5-CARBOXYLATE REDUCTASE PYRROLINE-5-CARBOXYLATE REDUCTASE oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;proteinogenic amino acid metabolic process#GO:0170039;heterocycle metabolic process#GO:0046483;proteinogenic amino acid biosynthetic process#GO:0170038;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;organic cyclic compound metabolic process#GO:1901360;alpha-amino acid biosynthetic process#GO:1901607;nitrogen compound metabolic process#GO:0006807;amino acid biosynthetic process#GO:0008652;alpha-amino acid metabolic process#GO:1901605;small molecule biosynthetic process#GO:0044283;L-amino acid biosynthetic process#GO:0170034;carboxylic acid metabolic process#GO:0019752;L-amino acid metabolic process#GO:0170033;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 reductase#PC00198;oxidoreductase#PC00176 Proline biosynthesis#P02768>Pyrroline-5-carboxylate reductase#P03113 CIOIN|Ensembl=ENSCING00000013787.2|UniProtKB=F6REF5 F6REF5 PTHR10827:SF52 RETICULOCALBIN IP16409P cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 calmodulin-related#PC00061 CIOIN|Ensembl=ENSCING00000011362.2|UniProtKB=F6Y7T8 F6Y7T8 PTHR23147:SF68 SERINE/ARGININE RICH SPLICING FACTOR SPLICING FACTOR, ARGININE_SERINE-RICH 2-RELATED nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;nuclear speck#GO:0016607;organelle#GO:0043226;nuclear body#GO:0016604;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA splicing factor#PC00148;RNA processing factor#PC00147;RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000009632.3|UniProtKB=F6ZU97 F6ZU97 PTHR11133:SF22 SACCHAROPINE DEHYDROGENASE ALPHA-AMINOADIPIC SEMIALDEHYDE SYNTHASE, MITOCHONDRIAL dehydrogenase#PC00092;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000010830.3|UniProtKB=F6WX23 F6WX23 LOC100185410 PTHR10410:SF3 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 -RELATED EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT H nucleic acid binding#GO:0003676;translation regulator activity#GO:0045182;metallopeptidase activity#GO:0008237;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;translation initiation factor activity#GO:0003743;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;translation regulator activity, nucleic acid binding#GO:0090079;translation factor activity, RNA binding#GO:0008135 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;translational initiation#GO:0006413;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;eukaryotic translation initiation factor 3 complex#GO:0005852;intracellular anatomical structure#GO:0005622 translation initiation factor#PC00224;translation factor#PC00223 CIOIN|Ensembl=ENSCING00000020931.1|UniProtKB=H2XZN3 H2XZN3 PTHR16119:SF17 TRANSMEMBRANE PROTEIN 144 TRANSMEMBRANE PROTEIN 144 CIOIN|Ensembl=ENSCING00000012676.1|UniProtKB=F6U3Y9 F6U3Y9 PTHR36978:SF4 P-LOOP CONTAINING NUCLEOTIDE TRIPHOSPHATE HYDROLASE P-LOOP CONTAINING NUCLEOSIDE TRIPHOSPHATE HYDROLASE PROTEIN metabolite interconversion enzyme#PC00262;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000018585.1|UniProtKB=H2Y127 H2Y127 PTHR22911:SF6 ACYL-MALONYL CONDENSING ENZYME-RELATED SOLUTE CARRIER FAMILY 35 MEMBER G1 cellular anatomical entity#GO:0110165;membrane#GO:0016020 transporter#PC00227 CIOIN|Ensembl=ENSCING00000011605.2|UniProtKB=F7B963 F7B963 PTHR11644:SF2 CYTIDINE DEAMINASE CYTIDINE DEAMINASE cation binding#GO:0043169;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;small molecule binding#GO:0036094;zinc ion binding#GO:0008270;binding#GO:0005488;catalytic activity#GO:0003824;transition metal ion binding#GO:0046914;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;metal ion binding#GO:0046872;deaminase activity#GO:0019239;ion binding#GO:0043167 cellular aromatic compound metabolic process#GO:0006725;nucleoside metabolic process#GO:0009116;glycosyl compound catabolic process#GO:1901658;carbohydrate derivative metabolic process#GO:1901135;heterocycle catabolic process#GO:0046700;pyrimidine-containing compound metabolic process#GO:0072527;organonitrogen compound catabolic process#GO:1901565;nucleobase-containing compound metabolic process#GO:0006139;cellular nitrogen compound catabolic process#GO:0044270;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;catabolic process#GO:0009056;nucleoside catabolic process#GO:0009164;organic substance catabolic process#GO:1901575;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248;heterocycle metabolic process#GO:0046483;carbohydrate derivative catabolic process#GO:1901136;cellular metabolic process#GO:0044237;organonitrogen compound metabolic process#GO:1901564;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;small molecule catabolic process#GO:0044282;aromatic compound catabolic process#GO:0019439;nucleobase-containing small molecule catabolic process#GO:0034656;organic cyclic compound catabolic process#GO:1901361;nucleobase-containing compound catabolic process#GO:0034655;glycosyl compound metabolic process#GO:1901657;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 deaminase#PC00088;hydrolase#PC00121 Salvage pyrimidine ribonucleotides#P02775>Cytidine deaminase#P03154;Salvage pyrimidine deoxyribonucleotides#P02774>Cytidine deaminase#P03144;Pyrimidine Metabolism#P02771>Cytidine Deaminase#P03130 CIOIN|Ensembl=ENSCING00000003718.3|UniProtKB=F6TIZ3 F6TIZ3 PTHR13140:SF729 MYOSIN UNCONVENTIONAL MYOSIN-IE microfilament motor activity#GO:0000146;cytoskeletal protein binding#GO:0008092;ATP-dependent activity#GO:0140657;binding#GO:0005488;actin filament binding#GO:0051015;cytoskeletal motor activity#GO:0003774;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779 localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;establishment of localization#GO:0051234;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;transport#GO:0006810;endocytosis#GO:0006897;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987;import into cell#GO:0098657 microvillus#GO:0005902;actin-based cell projection#GO:0098858;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cytoskeleton#GO:0005856;cell projection#GO:0042995;plasma membrane#GO:0005886 actin binding motor protein#PC00040 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 CIOIN|Ensembl=ENSCING00000003987.3|UniProtKB=F6Z227 F6Z227 PTHR14650:SF1 PROLYL HYDROXYLASE-RELATED 2-OXOGLUTARATE AND IRON-DEPENDENT OXYGENASE DOMAIN-CONTAINING PROTEIN 3 cellular anatomical entity#GO:0110165;membrane#GO:0016020 protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000004135.3|UniProtKB=F6UIS2 F6UIS2 PTHR14469:SF0 SARCOMA ANTIGEN NY-SAR-23 FAMILY WITH SEQUENCE SIMILARITY 113 CIOIN|Ensembl=ENSCING00000013710.2|UniProtKB=F6PRC5 F6PRC5 PTHR22605:SF16 RZ-TYPE DOMAIN-CONTAINING PROTEIN E3 UBIQUITIN-PROTEIN LIGASE RNF213 CIOIN|Ensembl=ENSCING00000005669.3|UniProtKB=F6YY65 F6YY65 PTHR11878:SF76 SODIUM/CALCIUM EXCHANGER CALX-BETA DOMAIN-CONTAINING PROTEIN calcium ion transmembrane transporter activity#GO:0015085;secondary active transmembrane transporter activity#GO:0015291;inorganic molecular entity transmembrane transporter activity#GO:0015318;antiporter activity#GO:0015297;transmembrane transporter activity#GO:0022857;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;active monoatomic ion transmembrane transporter activity#GO:0022853;monoatomic cation transmembrane transporter activity#GO:0008324;monoatomic ion transmembrane transporter activity#GO:0015075;inorganic cation transmembrane transporter activity#GO:0022890;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;calcium ion transmembrane transport#GO:0070588;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;calcium ion transport#GO:0006816;localization#GO:0051179;calcium ion import#GO:0070509;import across plasma membrane#GO:0098739;sodium ion transport#GO:0006814;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;calcium ion transmembrane import into cytosol#GO:0097553;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;import into cell#GO:0098657;sodium ion transmembrane transport#GO:0035725 synapse#GO:0045202;neuron projection#GO:0043005;cell junction#GO:0030054;postsynapse#GO:0098794;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;sarcolemma#GO:0042383;axon#GO:0030424;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000004800.3|UniProtKB=F6RE26 F6RE26 PTHR19143:SF458 FIBRINOGEN/TENASCIN/ANGIOPOEITIN FIBRINOGEN C-TERMINAL DOMAIN-CONTAINING PROTEIN-RELATED external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 CIOIN|Ensembl=ENSCING00000004071.3|UniProtKB=F7ANB6 F7ANB6 PTHR20931:SF0 TETRATRICOPEPTIDE REPEAT PROTEIN 30 TETRATRICOPEPTIDE REPEAT PROTEIN 30 protein-containing complex binding#GO:0044877;binding#GO:0005488 cilium organization#GO:0044782;cellular localization#GO:0051641;cell projection organization#GO:0030030;transport#GO:0006810;microtubule-based movement#GO:0007018;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;transport along microtubule#GO:0010970;intraciliary transport#GO:0042073;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;microtubule-based transport#GO:0099111;establishment of localization#GO:0051234;microtubule-based process#GO:0007017;organelle organization#GO:0006996;cytoskeleton-dependent intracellular transport#GO:0030705;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;protein-containing complex localization#GO:0031503 supramolecular complex#GO:0099080;axoneme#GO:0005930;cytoplasmic microtubule#GO:0005881;cytoplasmic region#GO:0099568;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;supramolecular fiber#GO:0099512;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intraciliary transport particle B#GO:0030992;microtubule cytoskeleton#GO:0015630;ciliary plasm#GO:0097014;membrane-bounded organelle#GO:0043227;plasma membrane bounded cell projection cytoplasm#GO:0032838;cell projection#GO:0042995;cytoskeleton#GO:0005856;cilium#GO:0005929;microtubule#GO:0005874;intraciliary transport particle#GO:0030990;axonemal microtubule#GO:0005879 CIOIN|Ensembl=ENSCING00000001837.3|UniProtKB=F6T7R0 F6T7R0 PTHR24031:SF125 RNA HELICASE ATP-DEPENDENT RNA HELICASE DDX42 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA helicase#PC00032 CIOIN|Ensembl=ENSCING00000005838.3|UniProtKB=F6V6J6 F6V6J6 PTHR11552:SF147 GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE CHOLINE DEHYDROGENASE, MITOCHONDRIAL oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000018479.1|UniProtKB=H2XZ02 H2XZ02 PTHR11202:SF3 SPROUTY-RELATED, EVH1 DOMAIN-CONTAINING PROTEIN FAMILY MEMBER SPROUTY-RELATED PROTEIN WITH EVH-1 DOMAIN, ISOFORM C enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;binding#GO:0005488;kinase binding#GO:0019900 regulation of cell communication#GO:0010646;regulation of MAPK cascade#GO:0043408;negative regulation of biological process#GO:0048519;negative regulation of response to stimulus#GO:0048585;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;negative regulation of MAPK cascade#GO:0043409;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000005319.3|UniProtKB=F7B690 F7B690 PTHR18916:SF6 DYNACTIN 1-RELATED MICROTUBULE-BINDING DYNACTIN SUBUNIT 1 chaperone#PC00072 Huntington disease#P00029>Dynactin#P00781 CIOIN|Ensembl=ENSCING00000006107.3|UniProtKB=F6V2Z5 F6V2Z5 PTHR24223:SF330 ATP-BINDING CASSETTE SUB-FAMILY C ATP-BINDING CASSETTE SUB-FAMILY C MEMBER 10 transmembrane transporter activity#GO:0022857;primary active transmembrane transporter activity#GO:0015399;ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 localization#GO:0051179;establishment of localization#GO:0051234;cellular process#GO:0009987;transmembrane transport#GO:0055085;transport#GO:0006810 cellular anatomical entity#GO:0110165;membrane#GO:0016020 ATP-binding cassette (ABC) transporter#PC00003;transporter#PC00227 CIOIN|Ensembl=ENSCING00000006076.4|UniProtKB=F6ZFK4 F6ZFK4 PTHR10799:SF923 SNF2/RAD54 HELICASE FAMILY LYMPHOID-SPECIFIC HELICASE ATP-dependent activity, acting on DNA#GO:0008094;nucleic acid binding#GO:0003676;ATP-dependent activity#GO:0140657;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on DNA#GO:0140097 DNA helicase#PC00011;DNA metabolism protein#PC00009 Wnt signaling pathway#P00057>SWI/SNF#P01435 CIOIN|Ensembl=ENSCING00000015878.2|UniProtKB=A0A1W2WF56 A0A1W2WF56 LOC100179127 PTHR15362:SF15 PHOSPHATIDYLINOSITOL SYNTHASE PHOSPHATIDYLSERINE SYNTHASE 1 transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000005172.3|UniProtKB=Q86SC5 Q86SC5 Ci-thymosin beta PTHR12021:SF26 THYMOSIN BETA THYMOSIN BETA cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;actin binding#GO:0003779;binding#GO:0005488;actin monomer binding#GO:0003785 negative regulation of protein polymerization#GO:0032272;cellular localization#GO:0051641;negative regulation of biological process#GO:0048519;macromolecule localization#GO:0033036;regulation of locomotion#GO:0040012;regulation of cellular component organization#GO:0051128;regulation of actin polymerization or depolymerization#GO:0008064;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;regulation of protein-containing complex assembly#GO:0043254;regulation of cell migration#GO:0030334;regulation of biological quality#GO:0065008;regulation of cellular component biogenesis#GO:0044087;negative regulation of organelle organization#GO:0010639;regulation of actin cytoskeleton organization#GO:0032956;regulation of actin filament-based process#GO:0032970;negative regulation of cellular component organization#GO:0051129;regulation of protein polymerization#GO:0032271;negative regulation of cellular process#GO:0048523;regulation of anatomical structure size#GO:0090066;regulation of cell motility#GO:2000145;regulation of actin filament length#GO:0030832;regulation of organelle organization#GO:0033043;regulation of actin filament organization#GO:0110053;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of actin filament polymerization#GO:0030833;regulation of cellular component size#GO:0032535;protein localization#GO:0008104;negative regulation of supramolecular fiber organization#GO:1902904;regulation of supramolecular fiber organization#GO:1902903;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;maintenance of location#GO:0051235;regulation of cellular process#GO:0050794;negative regulation of actin filament polymerization#GO:0030837;maintenance of location in cell#GO:0051651;biological regulation#GO:0065007;negative regulation of protein-containing complex assembly#GO:0031333;negative regulation of cytoskeleton organization#GO:0051494 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 CIOIN|Ensembl=ENSCING00000001404.3|UniProtKB=F6ZAR8 F6ZAR8 LOC100186702 PTHR22118:SF14 DYNEIN ASSEMBLY FACTOR 3, AXONEMAL DYNEIN AXONEMAL ASSEMBLY FACTOR 3 cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cell projection organization#GO:0030030;protein-containing complex assembly#GO:0065003;microtubule cytoskeleton organization#GO:0000226;cellular component organization#GO:0016043;axoneme assembly#GO:0035082;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;microtubule bundle formation#GO:0001578;axonemal dynein complex assembly#GO:0070286;cytoskeleton organization#GO:0007010;plasma membrane bounded cell projection assembly#GO:0120031;motile cilium assembly#GO:0044458 chaperone#PC00072 CIOIN|Ensembl=ENSCING00000020954.1|UniProtKB=F6TT30 F6TT30 PTHR12039:SF20 NICOTINAMIDE MONONUCLEOTIDE ADENYLYLTRANSFERASE NICOTINAMIDE_NICOTINIC ACID MONONUCLEOTIDE ADENYLYLTRANSFERASE 3-LIKE adenylyltransferase activity#GO:0070566;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779 cellular aromatic compound metabolic process#GO:0006725;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;pyridine nucleotide metabolic process#GO:0019362;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;nucleotide biosynthetic process#GO:0009165;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;pyridine-containing compound metabolic process#GO:0072524;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;nicotinamide nucleotide metabolic process#GO:0046496;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 nucleotidyltransferase#PC00174 CIOIN|Ensembl=ENSCING00000020902.1|UniProtKB=H2XP55 H2XP55 PTHR12955:SF1 SARCOMA ANTIGEN NY-SAR-95-RELATED INTEGRATOR COMPLEX SUBUNIT 13 localization#GO:0051179;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;centrosome localization#GO:0051642;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;cellular process#GO:0009987;regulation of mitotic cell cycle#GO:0007346 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;integrator complex#GO:0032039;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000004803.3|UniProtKB=F6REB0 F6REB0 PTHR11537:SF105 VOLTAGE-GATED POTASSIUM CHANNEL POTASSIUM VOLTAGE-GATED CHANNEL PROTEIN SHAL monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated potassium channel activity#GO:0005249;channel activity#GO:0015267;transporter activity#GO:0005215;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;regulation of membrane potential#GO:0042391;action potential#GO:0001508;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;localization#GO:0051179;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;monoatomic cation transport#GO:0006812;potassium ion transmembrane transport#GO:0071805;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;potassium ion transport#GO:0006813 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;voltage-gated potassium channel complex#GO:0008076;cation channel complex#GO:0034703;plasma membrane#GO:0005886 transporter#PC00227;voltage-gated ion channel#PC00241 CIOIN|Ensembl=ENSCING00000012619.2|UniProtKB=F6XE19 F6XE19 LOC100186632 PTHR10127:SF780 DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING METALLOENDOPEPTIDASE hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000021232.1|UniProtKB=H2XWK5 H2XWK5 PTHR15245:SF20 SYMPLEKIN-RELATED SYMPLEKIN cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;RNA processing#GO:0006396;mRNA polyadenylation#GO:0006378;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;mRNA 3'-end processing#GO:0031124;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;mRNA processing#GO:0006397;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;mRNA cleavage factor complex#GO:0005849;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;mRNA cleavage and polyadenylation specificity factor complex#GO:0005847;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000002853.3|UniProtKB=F6TN66 F6TN66 LOC100187188 PTHR11929:SF145 ALPHA- 1,3 -FUCOSYLTRANSFERASE ALPHA-(1,3)-FUCOSYLTRANSFERASE FUT-1 transferase activity#GO:0016740;fucosyltransferase activity#GO:0008417;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 glycosylation#GO:0070085;metabolic process#GO:0008152 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000006239.3|UniProtKB=F6XNT2 F6XNT2 LOC100183113 PTHR10857:SF102 COPINE C2 DOMAIN-CONTAINING PROTEIN lipid binding#GO:0008289;phospholipid binding#GO:0005543;binding#GO:0005488 response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;cellular process#GO:0009987;response to chemical#GO:0042221 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 calcium-binding protein#PC00060 CIOIN|Ensembl=ENSCING00000019081.1|UniProtKB=H2Y0G1 H2Y0G1 PTHR44329:SF285 SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED V-MOS MOLONEY MURINE SARCOMA VIRAL ONCO HOMOLOG transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000011919.2|UniProtKB=F6VXK0 F6VXK0 LOC100181604 PTHR43975:SF2 ZGC:101858 EG:BACR7A4.14 PROTEIN-RELATED CIOIN|Ensembl=ENSCING00000012399.2|UniProtKB=F6YQB8 F6YQB8 LOC100175486 PTHR43329:SF141 EPOXIDE HYDROLASE AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN-RELATED hydrolase activity#GO:0016787;catalytic activity#GO:0003824 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000007863.1|UniProtKB=F6U516 F6U516 LOC100185653 PTHR16222:SF34 ADP-RIBOSYLGLYCOHYDROLASE ADP-RIBOSYLGLYCOHYDROLASE metabolite interconversion enzyme#PC00262;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000024164.1|UniProtKB=H2XS18 H2XS18 LOC100176104 PTHR15111:SF0 RNA POLYMERASE II SUBUNIT 5-MEDIATING PROTEIN NNX3 UNCONVENTIONAL PREFOLDIN RPB5 INTERACTOR 1 molecular adaptor activity#GO:0060090;phosphatase regulator activity#GO:0019208;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714;binding#GO:0005488;molecular function regulator activity#GO:0098772;chromatin binding#GO:0003682;protein-macromolecule adaptor activity#GO:0030674;protein-containing complex binding#GO:0044877;enzyme inhibitor activity#GO:0004857;phosphatase inhibitor activity#GO:0019212;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234 negative regulation of hydrolase activity#GO:0051346;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of phosphate metabolic process#GO:0019220;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;regulation of transcription by RNA polymerase II#GO:0006357;regulation of dephosphorylation#GO:0035303;regulation of RNA biosynthetic process#GO:2001141;regulation of catalytic activity#GO:0050790;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;regulation of molecular function#GO:0065009;regulation of biosynthetic process#GO:0009889;regulation of hydrolase activity#GO:0051336;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;negative regulation of biosynthetic process#GO:0009890;regulation of DNA-templated transcription#GO:0006355;negative regulation of phosphorus metabolic process#GO:0010563;regulation of phosphatase activity#GO:0010921;negative regulation of metabolic process#GO:0009892;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of phosphate metabolic process#GO:0045936;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of catalytic activity#GO:0043086;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;negative regulation of molecular function#GO:0044092;regulation of cellular metabolic process#GO:0031323 chromatin/chromatin-binding, or -regulatory protein#PC00077 CIOIN|Ensembl=ENSCING00000014190.2|UniProtKB=F7A7A0 F7A7A0 LOC100178763 PTHR10996:SF277 2-HYDROXYACID DEHYDROGENASE-RELATED GLYOXYLATE REDUCTASE_HYDROXYPYRUVATE REDUCTASE oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000008136.3|UniProtKB=F6W2C6 F6W2C6 PTHR12271:SF66 POLY A POLYMERASE CID PAP -RELATED TERMINAL URIDYLYLTRANSFERASE TAILOR catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on RNA#GO:0140098;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;RNA 3'-end processing#GO:0031123;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 nucleotidyltransferase#PC00174 CIOIN|Ensembl=ENSCING00000006476.3|UniProtKB=F6Q2J0 F6Q2J0 PTHR24412:SF497 KELCH PROTEIN KELCH-LIKE PROTEIN 18 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000005531.3|UniProtKB=F6Y444 F6Y444 PTHR16441:SF0 FIDIPIDINE COILED-COIL DOMAIN-CONTAINING PROTEIN 93 localization#GO:0051179;localization within membrane#GO:0051668;cellular localization#GO:0051641;vesicle-mediated transport to the plasma membrane#GO:0098876;establishment of localization#GO:0051234;post-Golgi vesicle-mediated transport#GO:0006892;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;Golgi to plasma membrane transport#GO:0006893 CIOIN|Ensembl=ENSCING00000007417.3|UniProtKB=F7B946 F7B946 PTHR22957:SF661 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN GH16847P nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 regulation of molecular function#GO:0065009;regulation of GTPase activity#GO:0043087;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;activation of GTPase activity#GO:0090630;biological regulation#GO:0065007;positive regulation of molecular function#GO:0044093;regulation of hydrolase activity#GO:0051336;regulation of catalytic activity#GO:0050790;positive regulation of hydrolase activity#GO:0051345 GTPase-activating protein#PC00257 CIOIN|Ensembl=ENSCING00000001939.3|UniProtKB=F6ZIA7 F6ZIA7 LOC100187476 PTHR24150:SF8 ANKYRIN REPEAT AND MYND DOMAIN-CONTAINING PROTEIN 2 ANKYRIN REPEAT AND MYND DOMAIN-CONTAINING PROTEIN 2 CIOIN|Ensembl=ENSCING00000007644.3|UniProtKB=F6VXD0 F6VXD0 LOC100175883 PTHR21294:SF8 ELECTRON TRANSFER FLAVOPROTEIN BETA-SUBUNIT ELECTRON TRANSFER FLAVOPROTEIN SUBUNIT BETA oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000020478|UniProtKB=Q4H3P5 Q4H3P5 Ci-DRIL1_2 PTHR15348:SF0 AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN ARID DOMAIN- CONTAINING PROTEIN DEAD RINGER PROTEIN B-CELL REGULATOR OF IGH TRANSCRIPTION BRIGHT PROTEIN DEAD RINGER nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218 CIOIN|Ensembl=ENSCING00000008172.3|UniProtKB=F6UQ90 F6UQ90 LOC100184396 PTHR22594:SF16 ASPARTYL/LYSYL-TRNA SYNTHETASE ASPARAGINE--TRNA LIGASE, CYTOPLASMIC catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;ligase activity#GO:0016874;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;peptide biosynthetic process#GO:0043043;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 aminoacyl-tRNA synthetase#PC00047;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000003034.3|UniProtKB=F6Q6T5 F6Q6T5 PTHR18947:SF28 HOOK PROTEINS GIRDIN, ISOFORM A cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 cellular localization#GO:0051641;transport#GO:0006810;microtubule cytoskeleton organization#GO:0000226;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;microtubule-based process#GO:0007017;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;cytoskeleton-dependent intracellular transport#GO:0030705;cytoskeleton organization#GO:0007010;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;cytoplasmic microtubule organization#GO:0031122 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150 CIOIN|Ensembl=ENSCING00000023211.1|UniProtKB=H2XXN2 H2XXN2 PTHR10845:SF259 REGULATOR OF G PROTEIN SIGNALING RGS DOMAIN-CONTAINING PROTEIN-RELATED G-protein modulator#PC00022;protein-binding activity modulator#PC00095;GTPase-activating protein#PC00257 CIOIN|Ensembl=ENSCING00000016950.2|UniProtKB=F7AK54 F7AK54 PTHR45694:SF18 GLUTAREDOXIN 2 GLUTAREDOXIN-1-RELATED disulfide oxidoreductase activity#GO:0015036;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;response to stress#GO:0006950;cellular response to chemical stimulus#GO:0070887;response to chemical#GO:0042221;cellular response to oxidative stress#GO:0034599;response to oxidative stress#GO:0006979;cellular response to stress#GO:0033554;cellular process#GO:0009987 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000006697.3|UniProtKB=F7ARX5 F7ARX5 PTHR10157:SF23 DOPAMINE BETA HYDROXYLASE RELATED MOXD1 HOMOLOG 1 hydroxylase#PC00122 CIOIN|Ensembl=ENSCING00000001969.3|UniProtKB=F6X4B8 F6X4B8 PTHR45678:SF9 MITOCHONDRIAL 2-OXODICARBOXYLATE CARRIER 1-RELATED CALCIUM-BINDING MITOCHONDRIAL CARRIER PROTEIN ARALAR1 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 localization#GO:0051179;establishment of localization#GO:0051234;transport#GO:0006810 secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000018959.1|UniProtKB=H2XSH4 H2XSH4 LOC100180638 PTHR42861:SF127 CALCIUM-TRANSPORTING ATPASE CALCIUM-TRANSPORTING ATPASE SARCOPLASMIC_ENDOPLASMIC RETICULUM TYPE calcium ion transmembrane transporter activity#GO:0015085;inorganic molecular entity transmembrane transporter activity#GO:0015318;transmembrane transporter activity#GO:0022857;primary active transmembrane transporter activity#GO:0015399;ATP-dependent activity#GO:0140657;metal ion transmembrane transporter activity#GO:0046873;active monoatomic ion transmembrane transporter activity#GO:0022853;P-type ion transporter activity#GO:0015662;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;ATPase-coupled transmembrane transporter activity#GO:0042626;monoatomic cation transmembrane transporter activity#GO:0008324;monoatomic ion transmembrane transporter activity#GO:0015075;inorganic cation transmembrane transporter activity#GO:0022890;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;calcium ion transmembrane transport#GO:0070588;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;homeostatic process#GO:0042592;monoatomic cation homeostasis#GO:0055080;inorganic ion transmembrane transport#GO:0098660;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;cellular process#GO:0009987;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;calcium ion transport#GO:0006816;monoatomic ion homeostasis#GO:0050801;localization#GO:0051179;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation transport#GO:0006812;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655 cellular anatomical entity#GO:0110165;membrane#GO:0016020 primary active transporter#PC00068;transporter#PC00227 CIOIN|Ensembl=ENSCING00000007186.3|UniProtKB=F6ZA98 F6ZA98 LOC100183606 PTHR23404:SF2 MOLYBDOPTERIN SYNTHASE RELATED MOLYBDOPTERIN SYNTHASE CATALYTIC SUBUNIT cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000004244.3|UniProtKB=F6YG27 F6YG27 PTHR11227:SF17 WD-REPEAT PROTEIN INTERACTING WITH PHOSPHOINOSIDES WIPI -RELATED AUTOPHAGY-RELATED 18A, ISOFORM E phosphatidylinositol-3-phosphate binding#GO:0032266;phosphatidylinositol bisphosphate binding#GO:1902936;small molecule binding#GO:0036094;binding#GO:0005488;lipid binding#GO:0008289;phosphatidylinositol binding#GO:0035091;anion binding#GO:0043168;ion binding#GO:0043167;phospholipid binding#GO:0005543;phosphatidylinositol phosphate binding#GO:1901981 cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;macroautophagy#GO:0016236;macromolecule localization#GO:0033036;macromolecule modification#GO:0043412;protein modification process#GO:0036211;autophagy of mitochondrion#GO:0000422;biosynthetic process#GO:0009058;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;cellular component disassembly#GO:0022411;nitrogen compound metabolic process#GO:0006807;catabolic process#GO:0009056;mitochondrion organization#GO:0007005;protein metabolic process#GO:0019538;protein lipidation#GO:0006497;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;cellular component assembly#GO:0022607;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organelle disassembly#GO:1903008;lipoprotein biosynthetic process#GO:0042158;protein localization#GO:0008104;primary metabolic process#GO:0044238;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;organelle organization#GO:0006996;autophagosome assembly#GO:0000045;lipoprotein metabolic process#GO:0042157;autophagy#GO:0006914 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;phagophore assembly site#GO:0000407;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;extrinsic component of membrane#GO:0019898 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000004516.3|UniProtKB=F7ASX2 F7ASX2 zf(c2h2)-102 PTHR12604:SF4 KU AUTOANTIGEN DNA HELICASE X-RAY REPAIR CROSS-COMPLEMENTING PROTEIN 5 telomeric DNA binding#GO:0042162;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;double-strand break repair#GO:0006302;telomere organization#GO:0032200;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;telomere maintenance#GO:0000723;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;double-strand break repair via nonhomologous end joining#GO:0006303;nucleic acid metabolic process#GO:0090304;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;response to stress#GO:0006950;organelle organization#GO:0006996;chromosome organization#GO:0051276;nitrogen compound metabolic process#GO:0006807;cellular response to stress#GO:0033554;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259;metabolic process#GO:0008152 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA helicase#PC00011;DNA metabolism protein#PC00009 CIOIN|Ensembl=ENSCING00000007377.3|UniProtKB=F6VBW9 F6VBW9 LOC100186471 PTHR46437:SF1 MORN REPEAT-CONTAINING PROTEIN 5 MORN REPEAT-CONTAINING PROTEIN 5 CIOIN|Ensembl=ENSCING00000004026.3|UniProtKB=Q5VHU5 Q5VHU5 amt-1 PTHR11730:SF6 AMMONIUM TRANSPORTER AMMONIUM TRANSPORTER localization#GO:0051179;inorganic ion homeostasis#GO:0098771;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;nitrogen compound transport#GO:0071705;homeostatic process#GO:0042592;inorganic ion transmembrane transport#GO:0098660;chemical homeostasis#GO:0048878;cellular process#GO:0009987 primary active transporter#PC00068;transporter#PC00227 CIOIN|Ensembl=ENSCING00000014218.2|UniProtKB=F6ZP37 F6ZP37 PTHR24113:SF12 RAN GTPASE-ACTIVATING PROTEIN 1 RAN GTPASE-ACTIVATING PROTEIN 1 nucleoside-triphosphatase regulator activity#GO:0060589;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;binding#GO:0005488;molecular function regulator activity#GO:0098772;enzyme binding#GO:0019899;protein binding#GO:0005515;enzyme activator activity#GO:0008047;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234 cellular localization#GO:0051641;regulation of GTPase activity#GO:0043087;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;transport#GO:0006810;activation of GTPase activity#GO:0090630;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;positive regulation of hydrolase activity#GO:0051345;localization#GO:0051179;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;regulation of molecular function#GO:0065009;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;regulation of hydrolase activity#GO:0051336;intracellular transport#GO:0046907;nuclear transport#GO:0051169 cytoplasm#GO:0005737;perinuclear region of cytoplasm#GO:0048471;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 GTPase-activating protein#PC00257 CIOIN|Ensembl=ENSCING00000001591.3|UniProtKB=F6VBS7 F6VBS7 LOC100185313 PTHR14119:SF17 HYDROLASE ISOCHORISMATASE DOMAIN-CONTAINING PROTEIN 1 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000008137.2|UniProtKB=F6W282 F6W282 PTHR22748:SF6 AP ENDONUCLEASE DNA-(APURINIC OR APYRIMIDINIC SITE) ENDONUCLEASE hydrolase activity, acting on ester bonds#GO:0016788;DNA exonuclease activity, producing 5'-phosphomonoesters#GO:0016895;3'-5'-DNA exonuclease activity#GO:0008296;nuclease activity#GO:0004518;DNA exonuclease activity#GO:0004529;catalytic activity#GO:0003824;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters#GO:0016796;hydrolase activity#GO:0016787;catalytic activity, acting on a nucleic acid#GO:0140640;DNA nuclease activity#GO:0004536;catalytic activity, acting on DNA#GO:0140097;phosphoric diester hydrolase activity#GO:0008081;exonuclease activity#GO:0004527;3'-5' exonuclease activity#GO:0008408;phosphoric ester hydrolase activity#GO:0042578 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;base-excision repair#GO:0006284;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;DNA damage response#GO:0006974;response to stress#GO:0006950;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular response to stress#GO:0033554;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 CIOIN|Ensembl=ENSCING00000003609.3|UniProtKB=F6U9D6 F6U9D6 PTHR11929:SF145 ALPHA- 1,3 -FUCOSYLTRANSFERASE ALPHA-(1,3)-FUCOSYLTRANSFERASE FUT-1 transferase activity#GO:0016740;fucosyltransferase activity#GO:0008417;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 glycosylation#GO:0070085;metabolic process#GO:0008152 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000015052.2|UniProtKB=F6S8G5 F6S8G5 PTHR22977:SF1 COX ASSEMBLY MITOCHONDRIAL PROTEIN COX ASSEMBLY MITOCHONDRIAL PROTEIN 2 HOMOLOG cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000010740.3|UniProtKB=F7B2Z0 F7B2Z0 PTHR46501:SF10 MYOMEGALIN CENTROSOMIN regulation of microtubule-based process#GO:0032886;positive regulation of organelle organization#GO:0010638;regulation of organelle organization#GO:0033043;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;centrosome cycle#GO:0007098;regulation of cellular component organization#GO:0051128;cellular component organization#GO:0016043;regulation of microtubule polymerization or depolymerization#GO:0031110;cellular process#GO:0009987;microtubule organizing center organization#GO:0031023;positive regulation of protein polymerization#GO:0032273;positive regulation of cellular process#GO:0048522;regulation of supramolecular fiber organization#GO:1902903;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of cytoskeleton organization#GO:0051493;regulation of protein-containing complex assembly#GO:0043254;microtubule-based process#GO:0007017;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;regulation of cellular component biogenesis#GO:0044087;regulation of microtubule cytoskeleton organization#GO:0070507;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;cell cycle#GO:0007049;cytoskeleton organization#GO:0007010;positive regulation of cellular component biogenesis#GO:0044089;regulation of protein polymerization#GO:0032271;positive regulation of biological process#GO:0048518 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;microtubule cytoskeleton#GO:0015630;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000001101.3|UniProtKB=F7AGI1 F7AGI1 PTHR11592:SF81 GLUTATHIONE PEROXIDASE GLUTATHIONE PEROXIDASE oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;antioxidant activity#GO:0016209;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 peroxidase#PC00180;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000018053.1|UniProtKB=H2XKL6 H2XKL6 PTHR46105:SF5 AGAP004733-PA ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 44 ISOFORM X1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 CIOIN|Ensembl=ENSCING00000018918.1|UniProtKB=H2XYE1 H2XYE1 PTHR13693:SF102 CLASS II AMINOTRANSFERASE/8-AMINO-7-OXONONANOATE SYNTHASE 2-AMINO-3-KETOBUTYRATE COENZYME A LIGASE, MITOCHONDRIAL transaminase#PC00216;transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000005124.3|UniProtKB=F6VYA1 F6VYA1 PTHR11785:SF512 AMINO ACID TRANSPORTER SOBREMESA, ISOFORM B L-amino acid transmembrane transporter activity#GO:0015179;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;amino acid transmembrane transporter activity#GO:0015171;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215;organic acid transmembrane transporter activity#GO:0005342 localization#GO:0051179;organic substance transport#GO:0071702;amino acid transmembrane transport#GO:0003333;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;amino acid transport#GO:0006865;organic anion transport#GO:0015711;organic acid transport#GO:0015849;transport#GO:0006810;nitrogen compound transport#GO:0071705;organic acid transmembrane transport#GO:1903825;carboxylic acid transport#GO:0046942;cellular process#GO:0009987;carboxylic acid transmembrane transport#GO:1905039 transporter#PC00227 CIOIN|Ensembl=ENSCING00000024820.1|UniProtKB=F6U9S1 F6U9S1 PTHR45943:SF1 E3 UBIQUITIN-PROTEIN LIGASE MYCBP2 E3 UBIQUITIN-PROTEIN LIGASE MYCBP2 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000005029.3|UniProtKB=F6TX13 F6TX13 LOC100182924 PTHR13437:SF2 NUCLEOPORIN P58/P45 NUCLEOPORIN-LIKE PROTEIN 1 NUCLEOPORIN P58_P45 signal sequence binding#GO:0005048;structural molecule activity#GO:0005198;structural constituent of nuclear pore#GO:0017056;binding#GO:0005488;peptide binding#GO:0042277;amide binding#GO:0033218 envelope#GO:0031975;nuclear pore#GO:0005643;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear envelope#GO:0005635;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622 transporter#PC00227 CIOIN|Ensembl=ENSCING00000021501.1|UniProtKB=F6R9M9 F6R9M9 PTHR23048:SF49 MYOSIN LIGHT CHAIN 1, 3 FI08416P-RELATED intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;myosin complex#GO:0016459;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 CIOIN|Ensembl=ENSCING00000019736.1|UniProtKB=H2XJG5 H2XJG5 PTHR48013:SF9 DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 5-RELATED DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 5 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;MAPK cascade#GO:0000165;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;cellular process#GO:0009987;signaling#GO:0023052 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 EGF receptor signaling pathway#P00018>MEK1-2#P00559;CCKR signaling map#P06959>MAP2K5#P07160 CIOIN|Ensembl=ENSCING00000025039.1|UniProtKB=H2XQ96 H2XQ96 PTHR44942:SF4 METHYLTRANSF_11 DOMAIN-CONTAINING PROTEIN METHYLTRANSFERASE TYPE 11 DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000012152.2|UniProtKB=F6Y2U7 F6Y2U7 PTHR21355:SF0 G-PROTEIN COUPLED RECEPTOR-ASSOCIATED PROTEIN LMBRD2 G-PROTEIN COUPLED RECEPTOR-ASSOCIATED PROTEIN LMBRD2 cellular anatomical entity#GO:0110165;membrane#GO:0016020 CIOIN|Ensembl=ENSCING00000018036.1|UniProtKB=H2XTP1 H2XTP1 PTHR23257:SF958 SERINE-THREONINE PROTEIN KINASE SERINE_THREONINE-PROTEIN KINASE WNK4 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000019983.1|UniProtKB=H2XZI3 H2XZI3 PTHR13229:SF2 PROTEIN KISH-A PROTEIN KISH-A-RELATED cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;nitrogen compound transport#GO:0071705;protein secretion#GO:0009306;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;establishment of protein localization to extracellular region#GO:0035592;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;secretion#GO:0046903;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;protein localization to extracellular region#GO:0071692;export from cell#GO:0140352;secretion by cell#GO:0032940 CIOIN|Ensembl=ENSCING00000002102.3|UniProtKB=F6ZS04 F6ZS04 PTHR13027:SF7 SAND PROTEIN-RELATED VACUOLAR FUSION PROTEIN MON1 HOMOLOG CIOIN|Ensembl=ENSCING00000005974.3|UniProtKB=F6VTH2 F6VTH2 LOC100179176 PTHR21255:SF23 T-COMPLEX-ASSOCIATED-TESTIS-EXPRESSED 1/ DYNEIN LIGHT CHAIN DYNEIN LIGHT CHAIN protein binding#GO:0005515;binding#GO:0005488 microtubule-based movement#GO:0007018;cellular process#GO:0009987;microtubule-based process#GO:0007017 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;microtubule cytoskeleton#GO:0015630;dynein complex#GO:0030286;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic dynein complex#GO:0005868;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;microtubule or microtubule-binding cytoskeletal protein#PC00157 CIOIN|Ensembl=ENSCING00000004940.3|UniProtKB=Q1RLG4 Q1RLG4 Ci-ZF(C3H)-5 PTHR45846:SF1 TRNA-DIHYDROURIDINE(47) SYNTHASE [NAD(P)(+)]-LIKE TRNA-DIHYDROURIDINE(47) SYNTHASE [NAD(P)(+)]-LIKE catalytic activity, acting on RNA#GO:0140098;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;binding#GO:0005488;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor#GO:0016628;organic cyclic compound binding#GO:0097159;catalytic activity, acting on a nucleic acid#GO:0140640;oxidoreductase activity#GO:0016491 RNA processing factor#PC00147 CIOIN|Ensembl=ENSCING00000012515.2|UniProtKB=A0A1W2WIN6 A0A1W2WIN6 LOC100179535 PTHR12233:SF1 VACUOLAR PROTEIN SORTING 26 RELATED VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 26 endosomal transport#GO:0016197;cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;cytosolic transport#GO:0016482;establishment of protein localization#GO:0045184;retrograde transport, endosome to Golgi#GO:0042147;protein localization#GO:0008104;localization#GO:0051179;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 cytoplasm#GO:0005737;membrane protein complex#GO:0098796;endosome#GO:0005768;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150 CIOIN|Ensembl=ENSCING00000000448.3|UniProtKB=F6ZED0 F6ZED0 LOC100184285 PTHR10840:SF0 PROGRAMMED CELL DEATH PROTEIN 5 PROGRAMMED CELL DEATH PROTEIN 5 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 protein-binding activity modulator#PC00095 CIOIN|Ensembl=ENSCING00000004521.3|UniProtKB=F7A9V2 F7A9V2 LOC100186144 PTHR11496:SF83 ALCOHOL DEHYDROGENASE HYDROXYACID-OXOACID TRANSHYDROGENASE, MITOCHONDRIAL oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000014175.2|UniProtKB=F7A7U9 F7A7U9 PTHR24369:SF212 ANTIGEN BSP, PUTATIVE-RELATED LEUCINE-RICH REPEAT-CONTAINING PROTEIN 4B-LIKE cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 CIOIN|Ensembl=ENSCING00000022521.1|UniProtKB=Q8I6J7 Q8I6J7 10 PTHR11486:SF159 FIBROBLAST GROWTH FACTOR FIBROBLAST GROWTH FACTOR molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;binding#GO:0005488;growth factor activity#GO:0008083;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;growth factor receptor binding#GO:0070851;protein binding#GO:0005515;signaling receptor binding#GO:0005102;fibroblast growth factor receptor binding#GO:0005104 positive regulation of gene expression#GO:0010628;regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;positive regulation of cell population proliferation#GO:0008284;positive regulation of protein modification process#GO:0031401;regulation of intracellular signal transduction#GO:1902531;response to fibroblast growth factor#GO:0071774;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;regulation of cell migration#GO:0030334;anatomical structure morphogenesis#GO:0009653;regulation of signal transduction#GO:0009966;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;cellular developmental process#GO:0048869;cellular response to endogenous stimulus#GO:0071495;positive regulation of phosphorus metabolic process#GO:0010562;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;positive regulation of cell communication#GO:0010647;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;fibroblast growth factor receptor signaling pathway#GO:0008543;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;regulation of locomotion#GO:0040012;response to growth factor#GO:0070848;animal organ development#GO:0048513;regulation of signaling#GO:0023051;developmental process#GO:0032502;positive regulation of MAPK cascade#GO:0043410;positive regulation of response to stimulus#GO:0048584;positive regulation of biosynthetic process#GO:0009891;cell differentiation#GO:0030154;response to endogenous stimulus#GO:0009719;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of intracellular signal transduction#GO:1902533;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;signaling#GO:0023052;regulation of cell communication#GO:0010646;positive regulation of protein phosphorylation#GO:0001934;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;regulation of cell population proliferation#GO:0042127;regulation of cell motility#GO:2000145;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;cellular response to growth factor stimulus#GO:0071363;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;animal organ morphogenesis#GO:0009887;cellular response to fibroblast growth factor stimulus#GO:0044344 cytoplasm#GO:0005737;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576;intracellular anatomical structure#GO:0005622 intercellular signal molecule#PC00207;growth factor#PC00112 CIOIN|Ensembl=ENSCING00000000566.3|UniProtKB=F6Q3Z9 F6Q3Z9 LOC100185345 PTHR16083:SF85 LEUCINE RICH REPEAT CONTAINING PROTEIN FI16115P1 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000005496.3|UniProtKB=F7BE27 F7BE27 LOC100183740 PTHR11705:SF153 PROTEASE FAMILY M14 CARBOXYPEPTIDASE A,B ZINC CARBOXYPEPTIDASE A 1-LIKE PROTEIN metalloexopeptidase activity#GO:0008235;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;metallocarboxypeptidase activity#GO:0004181;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;carboxypeptidase activity#GO:0004180 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 metalloprotease#PC00153;protease#PC00190 CIOIN|Ensembl=ENSCING00000000097.3|UniProtKB=F6T5V5 F6T5V5 PTHR15010:SF0 ACYLOXYACYL HYDROLASE ACYLOXYACYL HYDROLASE cation binding#GO:0043169;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167 lipid metabolic process#GO:0006629;macromolecule catabolic process#GO:0009057;carbohydrate derivative metabolic process#GO:1901135;negative regulation of biological process#GO:0048519;regulation of response to external stimulus#GO:0032101;negative regulation of response to stimulus#GO:0048585;carbohydrate derivative catabolic process#GO:1901136;macromolecule metabolic process#GO:0043170;regulation of response to stress#GO:0080134;negative regulation of inflammatory response#GO:0050728;lipid catabolic process#GO:0016042;negative regulation of defense response#GO:0031348;liposaccharide metabolic process#GO:1903509;primary metabolic process#GO:0044238;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of inflammatory response#GO:0050727;regulation of defense response#GO:0031347;biological regulation#GO:0065007;negative regulation of response to external stimulus#GO:0032102;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000013537.2|UniProtKB=F6YVN3 F6YVN3 PTHR11256:SF56 BCL-2 RELATED BCL-2 BCL-2 HOMOLOGY REGION 1-3 DOMAIN-CONTAINING PROTEIN protein binding#GO:0005515;binding#GO:0005488 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0043280;intrinsic apoptotic signaling pathway in response to DNA damage#GO:0008630;signal transduction#GO:0007165;positive regulation of cysteine-type endopeptidase activity#GO:2001056;regulation of protein metabolic process#GO:0051246;apoptotic mitochondrial changes#GO:0008637;regulation of cysteine-type endopeptidase activity#GO:2000116;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;positive regulation of proteolysis#GO:0045862;regulation of biological process#GO:0050789;activation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0006919;DNA damage response#GO:0006974;positive regulation of metabolic process#GO:0009893;regulation of molecular function#GO:0065009;apoptotic process#GO:0006915;cell death#GO:0008219;regulation of hydrolase activity#GO:0051336;mitochondrion organization#GO:0007005;intracellular signal transduction#GO:0035556;positive regulation of biological process#GO:0048518;positive regulation of peptidase activity#GO:0010952;signaling#GO:0023052;regulation of proteolysis#GO:0030162;cellular response to stimulus#GO:0051716;positive regulation of catalytic activity#GO:0043085;programmed cell death#GO:0012501;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of hydrolase activity#GO:0051345;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;intrinsic apoptotic signaling pathway#GO:0097193;apoptotic signaling pathway#GO:0097190;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;response to stress#GO:0006950;extrinsic apoptotic signaling pathway#GO:0097191;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of endopeptidase activity#GO:0052548;regulation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0043281;regulation of peptidase activity#GO:0052547;release of cytochrome c from mitochondria#GO:0001836;cellular response to stress#GO:0033554;positive regulation of endopeptidase activity#GO:0010950;regulation of metabolic process#GO:0019222 bounding membrane of organelle#GO:0098588;envelope#GO:0031975;mitochondrial membrane#GO:0031966;mitochondrial outer membrane#GO:0005741;intracellular membrane-bounded organelle#GO:0043231;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867 CIOIN|Ensembl=ENSCING00000001702.2|UniProtKB=F6UJF1 F6UJF1 PTHR31441:SF2 FOLLICULIN FAMILY MEMBER FOLLICULIN nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 regulation of cell communication#GO:0010646;positive regulation of TORC1 signaling#GO:1904263;regulation of TORC1 signaling#GO:1903432;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;regulation of TOR signaling#GO:0032006;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;regulation of cellular process#GO:0050794;positive regulation of TOR signaling#GO:0032008;regulation of signal transduction#GO:0009966;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000004580.3|UniProtKB=A0A1W3JV04 A0A1W3JV04 PTHR10627:SF31 SCP160 DODECA-SATELLITE-BINDING PROTEIN 1, ISOFORM A nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000013545.2|UniProtKB=H2XQ06 H2XQ06 PTHR10188:SF8 L-ASPARAGINASE THREONINE ASPARTASE 1 hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 protease#PC00190;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000021575.1|UniProtKB=H2XS58 H2XS58 PTHR10316:SF40 MEMBRANE ASSOCIATED GUANYLATE KINASE-RELATED LD27118P regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000016188.2|UniProtKB=F6S6P6 F6S6P6 PTHR14191:SF3 PDZ DOMAIN CONTAINING PROTEIN NA(+)_H(+) EXCHANGE REGULATORY COFACTOR-LIKE PROTEIN NRFL-1 protein-membrane adaptor activity#GO:0043495;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 localization#GO:0051179;protein localization to plasma membrane#GO:0072659;protein localization to cell periphery#GO:1990778;localization within membrane#GO:0051668;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;protein localization to membrane#GO:0072657;cellular process#GO:0009987;protein localization#GO:0008104 plasma membrane region#GO:0098590;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;apical part of cell#GO:0045177;plasma membrane#GO:0005886;apical plasma membrane#GO:0016324 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000020505.1|UniProtKB=H2Y276 H2Y276 LOC100185540 PTHR46884:SF1 COLLECTRIN COLLECTRIN EGF receptor signaling pathway#P00018>Ras#P00552 CIOIN|Ensembl=ENSCING00000013931.2|UniProtKB=F6PQ74 F6PQ74 PTHR10658:SF54 PHOSPHATIDYLINOSITOL TRANSFER PROTEIN CYTOPLASMIC PHOSPHATIDYLINOSITOL TRANSFER PROTEIN 1 cation binding#GO:0043169;phosphatidylcholine binding#GO:0031210;lipid transfer activity#GO:0120013;small molecule binding#GO:0036094;binding#GO:0005488;phosphatidylcholine transporter activity#GO:0008525;phospholipid transporter activity#GO:0005548;lipid binding#GO:0008289;ion binding#GO:0043167;phosphatidylinositol binding#GO:0035091;phospholipid binding#GO:0005543;transporter activity#GO:0005215;lipid transporter activity#GO:0005319 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 transporter#PC00227 CIOIN|Ensembl=ENSCING00000019801.1|UniProtKB=Q4H306 Q4H306 Ci-Orphan Wnt d PTHR12027:SF98 WNT RELATED PROTEIN WNT molecular function activator activity#GO:0140677;binding#GO:0005488;molecular function regulator activity#GO:0098772;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;cytokine activity#GO:0005125;G protein-coupled receptor binding#GO:0001664;signaling receptor binding#GO:0005102 cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;neurogenesis#GO:0022008;developmental process#GO:0032502;multicellular organism development#GO:0007275;cell communication#GO:0007154;cell fate commitment#GO:0045165;cell-cell signaling by wnt#GO:0198738;nervous system development#GO:0007399;cellular process#GO:0009987;regulation of biological process#GO:0050789;system development#GO:0048731;response to stimulus#GO:0050896;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;neuron differentiation#GO:0030182;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;cell-cell signaling#GO:0007267;signaling#GO:0023052;canonical Wnt signaling pathway#GO:0060070;Wnt signaling pathway#GO:0016055 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 intercellular signal molecule#PC00207 CIOIN|Ensembl=ENSCING00000019860.1|UniProtKB=H2XYS1 H2XYS1 KYNU PTHR14084:SF0 KYNURENINASE KYNURENINASE hydrolase activity#GO:0016787;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;heterocycle catabolic process#GO:0046700;biogenic amine metabolic process#GO:0006576;organonitrogen compound catabolic process#GO:1901565;cellular nitrogen compound catabolic process#GO:0044270;amino acid catabolic process#GO:0009063;organic cyclic compound metabolic process#GO:1901360;aromatic amino acid metabolic process#GO:0009072;nitrogen compound metabolic process#GO:0006807;alpha-amino acid metabolic process#GO:1901605;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248;heterocycle metabolic process#GO:0046483;amine metabolic process#GO:0009308;oxoacid metabolic process#GO:0043436;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;aromatic compound catabolic process#GO:0019439;organic cyclic compound catabolic process#GO:1901361;aromatic amino acid family catabolic process#GO:0009074;carboxylic acid metabolic process#GO:0019752;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000004895.3|UniProtKB=H2XSN5 H2XSN5 PTHR24184:SF6 SI:CH211-189E2.2 ANKYRIN REPEAT AND SAM DOMAIN-CONTAINING PROTEIN 3 membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;cilium#GO:0005929;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025 CIOIN|Ensembl=ENSCING00000018289.1|UniProtKB=H2XVQ2 H2XVQ2 PTHR11216:SF170 EH DOMAIN DYNAMIN ASSOCIATED PROTEIN 160, ISOFORM D localization#GO:0051179;endosomal transport#GO:0016197;cellular localization#GO:0051641;establishment of localization#GO:0051234;transport#GO:0006810;endocytosis#GO:0006897;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;cellular process#GO:0009987;import into cell#GO:0098657 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 membrane traffic protein#PC00150 CIOIN|Ensembl=ENSCING00000006585.3|UniProtKB=F6R0J7 F6R0J7 PTHR10127:SF889 DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING ZINC METALLOPROTEINASE NAS-6-LIKE hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 CIOIN|Gene=MTAP_CIOIN|UniProtKB=F6X2V8 F6X2V8 PTHR42679:SF2 S-METHYL-5'-THIOADENOSINE PHOSPHORYLASE S-METHYL-5'-THIOADENOSINE PHOSPHORYLASE transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;pentosyltransferase activity#GO:0016763;catalytic activity#GO:0003824 organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;proteinogenic amino acid metabolic process#GO:0170039;sulfur compound metabolic process#GO:0006790;proteinogenic amino acid biosynthetic process#GO:0170038;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;aspartate family amino acid biosynthetic process#GO:0009067;alpha-amino acid biosynthetic process#GO:1901607;nitrogen compound metabolic process#GO:0006807;amino acid biosynthetic process#GO:0008652;alpha-amino acid metabolic process#GO:1901605;aspartate family amino acid metabolic process#GO:0009066;small molecule biosynthetic process#GO:0044283;L-amino acid biosynthetic process#GO:0170034;carboxylic acid metabolic process#GO:0019752;L-amino acid metabolic process#GO:0170033;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 nucleotide kinase#PC00172 Purine metabolism#P02769>Nucleoside Phosphorylase#P03115 CIOIN|Ensembl=ENSCING00000007040.3|UniProtKB=Q4H3D0 Q4H3D0 Ci-Hox12 PTHR45804:SF10 SEGMENTATION PROTEIN FUSHI TARAZU-LIKE PROTEIN HOMEOBOX PROTEIN HOX-C11A-LIKE homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 CIOIN|Ensembl=ENSCING00000001153.3|UniProtKB=F6YBA5 F6YBA5 PTHR18934:SF99 ATP-DEPENDENT RNA HELICASE ATP-DEPENDENT RNA HELICASE DHX37-RELATED nucleic acid binding#GO:0003676;RNA binding#GO:0003723;helicase activity#GO:0004386;ATP-dependent activity#GO:0140657;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;catalytic activity, acting on a nucleic acid#GO:0140640 RNA helicase#PC00032 CIOIN|Ensembl=ENSCING00000007042.3|UniProtKB=F6ZVE7 F6ZVE7 LOC100175295 PTHR43323:SF2 3-HYDROXY-3-METHYLGLUTARYL COENZYME A SYNTHASE HYDROXYMETHYLGLUTARYL-COA SYNTHASE transferase activity#GO:0016740;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;phospholipid biosynthetic process#GO:0008654;organophosphate biosynthetic process#GO:0090407;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;lipid biosynthetic process#GO:0008610;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;amide metabolic process#GO:0043603;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;acyl-CoA metabolic process#GO:0006637;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;isoprenoid metabolic process#GO:0006720;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;isoprenoid biosynthetic process#GO:0008299;primary metabolic process#GO:0044238;terpenoid biosynthetic process#GO:0016114;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;cellular lipid metabolic process#GO:0044255;terpenoid metabolic process#GO:0006721;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 Cholesterol biosynthesis#P00014>Hydroxymethyl glutaryl CoA synthase#P00498 CIOIN|Ensembl=ENSCING00000008697.3|UniProtKB=F6WZE9 F6WZE9 LOC100180559 PTHR10083:SF381 KUNITZ-TYPE PROTEASE INHIBITOR-RELATED BPTI_KUNITZ INHIBITOR DOMAIN-CONTAINING PROTEIN peptidase inhibitor activity#GO:0030414;molecular function regulator activity#GO:0098772;serine-type endopeptidase inhibitor activity#GO:0004867;peptidase regulator activity#GO:0061134;enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;endopeptidase regulator activity#GO:0061135;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191;protein-binding activity modulator#PC00095 CIOIN|Ensembl=ENSCING00000021732.1|UniProtKB=A0A1W5BJ73 A0A1W5BJ73 zf(c2h2)-118 PTHR24377:SF1012 IP01015P-RELATED C2H2-TYPE DOMAIN-CONTAINING PROTEIN-RELATED C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 CIOIN|Ensembl=ENSCING00000021544.1|UniProtKB=H2XLQ3 H2XLQ3 LOC100175015 PTHR46152:SF3 NF-KAPPA-B INHIBITOR-INTERACTING RAS-LIKE PROTEIN NF-KAPPA-B INHIBITOR-INTERACTING RAS-LIKE PROTEIN protein binding#GO:0005515;binding#GO:0005488 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;small GTPase-mediated signal transduction#GO:0007264;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;cellular process#GO:0009987;signaling#GO:0023052 CIOIN|Ensembl=ENSCING00000010923.3|UniProtKB=Q4H3F7 Q4H3F7 Ci-GABPalpha PTHR11849:SF195 ETS GA-BINDING PROTEIN ALPHA CHAIN transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 PDGF signaling pathway#P00047>Ets#P01167 CIOIN|Ensembl=ENSCING00000011444.2|UniProtKB=F7ACS2 F7ACS2 PTHR44899:SF5 CAMK FAMILY PROTEIN KINASE PROTEIN KINASE DOMAIN-CONTAINING PROTEIN transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;kinase activity#GO:0016301;protein kinase activity#GO:0004672 non-receptor serine/threonine protein kinase#PC00167 CIOIN|Ensembl=ENSCING00000003676.3|UniProtKB=F6ZV18 F6ZV18 PTHR42698:SF1 GTPASE ERA GTPASE ERA, MITOCHONDRIAL nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159;ribosome binding#GO:0043022;ribonucleoprotein complex binding#GO:0043021;protein-containing complex binding#GO:0044877;rRNA binding#GO:0019843 organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;protein-RNA complex assembly#GO:0022618;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;ribonucleoprotein complex biogenesis#GO:0022613;protein-containing complex assembly#GO:0065003;protein-RNA complex organization#GO:0071826;cellular component organization#GO:0016043;ribosome biogenesis#GO:0042254;cellular process#GO:0009987;non-membrane-bounded organelle assembly#GO:0140694;ribosomal small subunit biogenesis#GO:0042274 RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000002618.3|UniProtKB=F7B2X5 F7B2X5 LOC100176828 PTHR12223:SF45 VESICULAR MANNOSE-BINDING LECTIN RE50040P carbohydrate binding#GO:0030246;small molecule binding#GO:0036094;binding#GO:0005488;monosaccharide binding#GO:0048029 localization#GO:0051179;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;establishment of localization#GO:0051234;transport#GO:0006810;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987 bounding membrane of organelle#GO:0098588;COPII-coated ER to Golgi transport vesicle#GO:0030134;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;coated vesicle#GO:0030135;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;Golgi membrane#GO:0000139;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 membrane traffic protein#PC00150 CIOIN|Ensembl=ENSCING00000018070.1|UniProtKB=H2Y320 H2Y320 PTHR12213:SF0 CORRINOID ADENOSYLTRANSFERASE CORRINOID ADENOSYLTRANSFERASE MMAB transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824 dehydrogenase#PC00092;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000008906.3|UniProtKB=F6QBF6 F6QBF6 LOC100187381 PTHR24410:SF41 HL07962P-RELATED HL07962P defense/immunity protein#PC00090 CIOIN|Ensembl=ENSCING00000009298.3|UniProtKB=F7B9K0 F7B9K0 PTHR24300:SF397 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 2U1 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;tetrapyrrole binding#GO:0046906;steroid hydroxylase activity#GO:0008395;oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497;heme binding#GO:0020037 response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;response to chemical#GO:0042221;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 oxygenase#PC00177;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000000484.3|UniProtKB=F6YVB6 F6YVB6 PTHR13343:SF17 CREG1 PROTEIN CELLULAR REPRESSOR OF E1A-STIMULATED GENES, ISOFORM A CIOIN|Ensembl=ENSCING00000020267.1|UniProtKB=H2XQM7 H2XQM7 LOC100178497 PTHR23064:SF68 TROPONIN EF-HAND DOMAIN-CONTAINING PROTEIN cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 CIOIN|Ensembl=ENSCING00000014624.2|UniProtKB=F7AHK4 F7AHK4 PTHR43655:SF8 ATP-DEPENDENT PROTEASE PARAPLEGIN mitochondrial protein processing#GO:0034982;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;protein processing#GO:0016485;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;peptidase complex#GO:1905368;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial envelope#GO:0005740;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227;mitochondrial protein-containing complex#GO:0098798 metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000014270.2|UniProtKB=F6XA69 F6XA69 LOC100180889 PTHR46331:SF2 VALACYCLOVIR HYDROLASE VALACYCLOVIR HYDROLASE hydrolase activity#GO:0016787;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000003435.3|UniProtKB=F6XL60 F6XL60 LOC100180481 PTHR10417:SF4 GLUCOCORTICOID MODULATORY ELEMENT-BINDING PROTEIN SAND DOMAIN-CONTAINING PROTEIN-RELATED CIOIN|Ensembl=ENSCING00000007205.3|UniProtKB=F6Y7R5 F6Y7R5 PTHR10742:SF410 FLAVIN MONOAMINE OXIDASE LYSINE-SPECIFIC HISTONE DEMETHYLASE 2 oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 oxidase#PC00175;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000004385.3|UniProtKB=F7AV16 F7AV16 PTHR10827:SF52 RETICULOCALBIN IP16409P cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 calmodulin-related#PC00061 CIOIN|Ensembl=ENSCING00000023754.1|UniProtKB=H2XU39 H2XU39 PTHR47037:SF1 39S RIBOSOMAL PROTEIN L33, MITOCHONDRIAL LARGE RIBOSOMAL SUBUNIT PROTEIN BL33M cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000021692.1|UniProtKB=H2XZK6 H2XZK6 PTHR11409:SF42 ADENOSINE DEAMINASE ADENOSINE DEAMINASE-LIKE PROTEIN hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;adenosine deaminase activity#GO:0004000;deaminase activity#GO:0019239;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;nucleoside metabolic process#GO:0009116;glycosyl compound catabolic process#GO:1901658;carbohydrate derivative metabolic process#GO:1901135;heterocycle catabolic process#GO:0046700;organonitrogen compound catabolic process#GO:1901565;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase metabolic process#GO:0009112;nucleobase-containing compound metabolic process#GO:0006139;cellular nitrogen compound catabolic process#GO:0044270;purine-containing compound catabolic process#GO:0072523;organic cyclic compound metabolic process#GO:1901360;purine nucleoside metabolic process#GO:0042278;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;purine-containing compound metabolic process#GO:0072521;catabolic process#GO:0009056;nucleoside catabolic process#GO:0009164;organic substance catabolic process#GO:1901575;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;carbohydrate derivative catabolic process#GO:1901136;purine nucleobase metabolic process#GO:0006144;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;purine nucleoside catabolic process#GO:0006152;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;aromatic compound catabolic process#GO:0019439;nucleobase-containing compound biosynthetic process#GO:0034654;small molecule catabolic process#GO:0044282;nucleobase-containing small molecule catabolic process#GO:0034656;adenosine metabolic process#GO:0046085;organic cyclic compound catabolic process#GO:1901361;aromatic compound biosynthetic process#GO:0019438;small molecule biosynthetic process#GO:0044283;nucleobase-containing compound catabolic process#GO:0034655;glycosyl compound metabolic process#GO:1901657;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 deaminase#PC00088;metabolite interconversion enzyme#PC00262;hydrolase#PC00121 Adenine and hypoxanthine salvage pathway#P02723>Adenosine deaminase#P02811;Adenine and hypoxanthine salvage pathway#P02723>Deoxyadenosine deaminase#P02807 CIOIN|Ensembl=ENSCING00000008083.3|UniProtKB=F6Z6K5 F6Z6K5 PTHR10928:SF2 SUPPRESSOR OF FUSED SUPPRESSOR OF FUSED HOMOLOG protein binding#GO:0005515;transcription factor binding#GO:0008134;binding#GO:0005488 cellular localization#GO:0051641;regulation of DNA-binding transcription factor activity#GO:0051090;macromolecule localization#GO:0033036;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;protein localization#GO:0008104;localization#GO:0051179;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cellular macromolecule localization#GO:0070727;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;maintenance of location#GO:0051235;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of molecular function#GO:0044092;regulation of cellular metabolic process#GO:0031323;negative regulation of DNA-binding transcription factor activity#GO:0043433 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 Hedgehog signaling pathway#P00025>Su(fu)#P00699 CIOIN|Ensembl=ENSCING00000001109.3|UniProtKB=F7AFW8 F7AFW8 PTHR13962:SF22 FORKHEAD BOX PROTEIN N3-LIKE PROTEIN-RELATED FORKHEAD BOX PROTEIN N3-LIKE PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 CIOIN|Ensembl=ENSCING00000024350.1|UniProtKB=H2Y076 H2Y076 PTHR43856:SF1 CARDIOLIPIN HYDROLASE MITOCHONDRIAL CARDIOLIPIN HYDROLASE catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a nucleic acid#GO:0140640;endonuclease activity#GO:0004519;RNA nuclease activity#GO:0004540;RNA endonuclease activity#GO:0004521 phospholipase#PC00186 CIOIN|Ensembl=ENSCING00000003138.3|UniProtKB=F6QJQ8 F6QJQ8 PTHR11647:SF1 HYDRANTOINASE/DIHYDROPYRIMIDINASE FAMILY MEMBER COLLAPSIN RESPONSE MEDIATOR PROTEIN metabolite interconversion enzyme#PC00262;hydrolase#PC00121 Axon guidance mediated by semaphorins#P00007>CRMP#P00339;Pyrimidine Metabolism#P02771>Dihydropyrimidinase#P03125 CIOIN|Ensembl=ENSCING00000001057.3|UniProtKB=F6UN42 F6UN42 LOC100175630 PTHR11362:SF147 PHOSPHATIDYLETHANOLAMINE-BINDING PROTEIN PHOSPHATIDYLETHANOLAMINE BINDING PROTEIN protease inhibitor#PC00191 EGF receptor signaling pathway#P00018>RKIP#P00548 CIOIN|Ensembl=ENSCING00000006089.3|UniProtKB=F6YXK3 F6YXK3 PTHR11049:SF24 ACYL COENZYME A THIOESTER HYDROLASE CYTOSOLIC ACYL COENZYME A THIOESTER HYDROLASE hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;fatty acyl-CoA hydrolase activity#GO:0047617;catalytic activity#GO:0003824;thiolester hydrolase activity#GO:0016790 cellular aromatic compound metabolic process#GO:0006725;lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;lipid catabolic process#GO:0016042;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;cellular lipid catabolic process#GO:0044242;amide metabolic process#GO:0043603;purine nucleotide metabolic process#GO:0006163;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;acyl-CoA metabolic process#GO:0006637;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;ribonucleotide metabolic process#GO:0009259;monocarboxylic acid metabolic process#GO:0032787;fatty acid catabolic process#GO:0009062;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;fatty acid metabolic process#GO:0006631;small molecule catabolic process#GO:0044282;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281;monocarboxylic acid catabolic process#GO:0072329 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 esterase#PC00097 CIOIN|Ensembl=ENSCING00000011464.2|UniProtKB=F6VXB1 F6VXB1 PTHR15139:SF0 TUBULIN FOLDING COFACTOR C TUBULIN-SPECIFIC CHAPERONE C cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein-containing complex assembly#GO:0065003;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nitrogen compound metabolic process#GO:0006807;protein-containing complex organization#GO:0043933;protein folding#GO:0006457;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 chaperone#PC00072 CIOIN|Ensembl=ENSCING00000004975.3|UniProtKB=F6X8Y9 F6X8Y9 LOC100187055 PTHR34257:SF2 ADAPTER PROTEIN CIKS E3 UBIQUITIN LIGASE TRAF3IP2 positive regulation of canonical NF-kappaB signal transduction#GO:0043123;regulation of cell communication#GO:0010646;immune response#GO:0006955;humoral immune response#GO:0006959;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;immune system process#GO:0002376;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;regulation of canonical NF-kappaB signal transduction#GO:0043122;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000024971.1|UniProtKB=Q4H2Z5 Q4H2Z5 Ci-Pax1_9 PTHR45636:SF16 PAIRED BOX PROTEIN PAX-6-RELATED-RELATED PAIRED BOX POX-MESO PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 homeodomain transcription factor#PC00119 CIOIN|Ensembl=ENSCING00000002414.3|UniProtKB=F6QHU2 F6QHU2 LOC100181128 PTHR13832:SF699 PROTEIN PHOSPHATASE 2C INTEGRIN-LINKED KINASE-ASSOCIATED SERINE_THREONINE PHOSPHATASE 2C macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;dephosphorylation#GO:0016311;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein dephosphorylation#GO:0006470;cellular metabolic process#GO:0044237;cellular process#GO:0009987;protein metabolic process#GO:0019538;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 protein phosphatase#PC00195;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000013001.2|UniProtKB=F6V6T7 F6V6T7 PTHR22906:SF43 PROPERDIN PROPERDIN CIOIN|Ensembl=ENSCING00000002803.3|UniProtKB=F6XMN3 F6XMN3 PTHR47977:SF90 RAS-RELATED PROTEIN RAB RAS AND EF-HAND DOMAIN-CONTAINING PROTEIN HOMOLOG GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;ion binding#GO:0043167;anion binding#GO:0043168 localization#GO:0051179;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization#GO:0051234;transport#GO:0006810 small GTPase#PC00208;G-protein#PC00020 CIOIN|Ensembl=ENSCING00000005497.3|UniProtKB=F7BD99 F7BD99 PTHR19143:SF458 FIBRINOGEN/TENASCIN/ANGIOPOEITIN FIBRINOGEN C-TERMINAL DOMAIN-CONTAINING PROTEIN-RELATED external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 CIOIN|Ensembl=ENSCING00000006641.3|UniProtKB=F6U155 F6U155 LOC100182476 PTHR24228:SF72 B2 BRADYKININ RECEPTOR/ANGIOTENSIN II RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 G-protein coupled receptor#PC00021 CIOIN|Ensembl=ENSCING00000002895.3|UniProtKB=F6SZT6 F6SZT6 PTHR11731:SF202 PROTEASE FAMILY S9B,C DIPEPTIDYL-PEPTIDASE IV-RELATED DIPEPTIDYL PEPTIDASE FAMILY MEMBER 2 hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 serine protease#PC00203;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000024728.1|UniProtKB=A0A1W2WJY0 A0A1W2WJY0 LOC100185947 PTHR21096:SF0 PROTEIN FAM136A PROTEIN FAM136A cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000012084.2|UniProtKB=F6XVK2 F6XVK2 PTHR24253:SF176 TRANSMEMBRANE PROTEASE SERINE CORIN, ISOFORM B serine protease#PC00203;protease#PC00190 CIOIN|Ensembl=ENSCING00000002826.4|UniProtKB=F6WYW5 F6WYW5 PTHR18929:SF132 PROTEIN DISULFIDE ISOMERASE PROTEIN DISULFIDE-ISOMERASE A3 isomerase activity#GO:0016853;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;protein disulfide isomerase activity#GO:0003756 cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;response to endoplasmic reticulum stress#GO:0034976;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;response to stress#GO:0006950;protein folding#GO:0006457;nitrogen compound metabolic process#GO:0006807;cellular response to stress#GO:0033554;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chaperone#PC00072 CIOIN|Ensembl=ENSCING00000016795.2|UniProtKB=A0A1W3JI75 A0A1W3JI75 LOC778626 PTHR10811:SF5 FRINGE-RELATED FRINGE GLYCOSYLTRANSFERASE acetylglucosaminyltransferase activity#GO:0008375;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194;hexosyltransferase activity#GO:0016758 glycosyltransferase#PC00111;metabolite interconversion enzyme#PC00262 Notch signaling pathway#P00045>Fringe#P01107 CIOIN|Ensembl=ENSCING00000005282.3|UniProtKB=F6UHI7 F6UHI7 LOC100183873 PTHR22851:SF0 U3 SMALL NUCLEOLAR RNA U3 SNORNA ASSOCIATED PROTEIN DDB1- AND CUL4-ASSOCIATED FACTOR 13 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;maturation of SSU-rRNA#GO:0030490;ribosomal small subunit biogenesis#GO:0042274;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;small-subunit processome#GO:0032040;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;nuclear lumen#GO:0031981 RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000018325.1|UniProtKB=H2XRD4 H2XRD4 LOC100178355 PTHR45697:SF2 ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 2-RELATED ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 2 carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein folding#GO:0006457;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000022236.1|UniProtKB=H2XJP4 H2XJP4 PTHR13468:SF1 DEK PROTEIN PROTEIN DEK protein binding#GO:0005515;binding#GO:0005488;histone binding#GO:0042393 regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of cellular response to stress#GO:0080135;regulation of double-strand break repair#GO:2000779;regulation of macromolecule metabolic process#GO:0060255;regulation of nitrogen compound metabolic process#GO:0051171;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of DNA metabolic process#GO:0051052;biological regulation#GO:0065007;regulation of response to stress#GO:0080134;regulation of DNA repair#GO:0006282;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 CIOIN|Ensembl=ENSCING00000008622.3|UniProtKB=Q1RL49 Q1RL49 Ci-ZF(RING_C6HC)-7 PTHR11685:SF371 RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING E3 UBIQUITIN-PROTEIN LIGASE RNF14 ubiquitin-like protein conjugating enzyme binding#GO:0044390;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;enzyme binding#GO:0019899;protein binding#GO:0005515;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;protein polyubiquitination#GO:0000209;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000006855.3|UniProtKB=F6ZXM0 F6ZXM0 LOC100180902 PTHR22883:SF414 ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN PALMITOYLTRANSFERASE ZDHHC24-RELATED palmitoyltransferase activity#GO:0016409;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular localization#GO:0051641;macromolecule localization#GO:0033036;macromolecule modification#GO:0043412;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;biosynthetic process#GO:0009058;establishment of protein localization#GO:0045184;establishment of protein localization to membrane#GO:0090150;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;protein palmitoylation#GO:0018345;protein metabolic process#GO:0019538;protein lipidation#GO:0006497;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;localization within membrane#GO:0051668;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein localization to membrane#GO:0072657;organonitrogen compound biosynthetic process#GO:1901566;protein targeting#GO:0006605;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;protein acylation#GO:0043543;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;lipoprotein biosynthetic process#GO:0042158;protein localization#GO:0008104;primary metabolic process#GO:0044238;localization#GO:0051179;protein targeting to membrane#GO:0006612;cellular macromolecule localization#GO:0070727;lipoprotein metabolic process#GO:0042157 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000000588.3|UniProtKB=F6PXM4 F6PXM4 LOC100183377 PTHR15750:SF2 VASOHIBIN-1-LIKE ISOFORM X2 VASOHIBIN CIOIN|Ensembl=ENSCING00000012920.2|UniProtKB=F6RMI2 F6RMI2 PTHR11607:SF3 ALPHA-MANNOSIDASE LYSOSOMAL ALPHA-MANNOSIDASE hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 glycosidase#PC00110;metabolite interconversion enzyme#PC00262;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000016527.2|UniProtKB=F6XHR2 F6XHR2 PTHR10283:SF135 SOLUTE CARRIER FAMILY 13 MEMBER SOLUTE CARRIER FAMILY 13 MEMBER 5 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 localization#GO:0051179;establishment of localization#GO:0051234;cellular process#GO:0009987;transmembrane transport#GO:0055085;transport#GO:0006810 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000005449.3|UniProtKB=A0A1W2W635 A0A1W2W635 LOC100179571 PTHR11753:SF5 ADAPTOR COMPLEXES SMALL SUBUNIT FAMILY AP COMPLEX SUBUNIT SIGMA localization#GO:0051179;vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234;cellular process#GO:0009987;transport#GO:0006810 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 vesicle coat protein#PC00235 CIOIN|Ensembl=ENSCING00000020950.1|UniProtKB=F6WBL5 F6WBL5 PTHR11616:SF182 SODIUM/CHLORIDE DEPENDENT TRANSPORTER TRANSPORTER metal ion transport#GO:0030001;transmembrane transport#GO:0055085;amino acid transport#GO:0006865;organic anion transport#GO:0015711;organic acid transport#GO:0015849;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;localization#GO:0051179;organic substance transport#GO:0071702;sodium ion transport#GO:0006814;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;sodium ion transmembrane transport#GO:0035725 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 primary active transporter#PC00068;transporter#PC00227 Adrenaline and noradrenaline biosynthesis#P00001>amine translocator#P00068 CIOIN|Ensembl=ENSCING00000021468.1|UniProtKB=H2XVU3 H2XVU3 PTHR13421:SF16 SNRNA-ACTIVATING PROTEIN COMPLEX SUBUNIT 3 SNRNA-ACTIVATING PROTEIN COMPLEX SUBUNIT 3 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;core promoter sequence-specific DNA binding#GO:0001046;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690 cellular aromatic compound metabolic process#GO:0006725;DNA-templated transcription#GO:0006351;RNA metabolic process#GO:0016070;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;heterocycle metabolic process#GO:0046483;snRNA metabolic process#GO:0016073;transcription by RNA polymerase III#GO:0006383;snRNA transcription by RNA polymerase II#GO:0042795;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;ncRNA transcription#GO:0098781;aromatic compound biosynthetic process#GO:0019438;transcription by RNA polymerase II#GO:0006366 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667 RNA metabolism protein#PC00031;general transcription factor#PC00259 CIOIN|Ensembl=ENSCING00000013253.2|UniProtKB=F6SFU4 F6SFU4 LOC100175156 PTHR34258:SF1 ARMADILLO-LIKE HELICAL DOMAIN CONTAINING PROTEIN 1 ARMADILLO-LIKE HELICAL DOMAIN CONTAINING PROTEIN 1 CIOIN|Ensembl=ENSCING00000003550.3|UniProtKB=F6YTL6 F6YTL6 LOC100182082 PTHR23073:SF24 26S PROTEASOME REGULATORY SUBUNIT 26S PROTEASOME REGULATORY SUBUNIT 4 ATP-dependent activity#GO:0140657 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 peptidase complex#GO:1905368;protein-containing complex#GO:0032991;proteasome accessory complex#GO:0022624;proteasome regulatory particle#GO:0005838;catalytic complex#GO:1902494;proteasome complex#GO:0000502;endopeptidase complex#GO:1905369;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 protease#PC00190;protein modifying enzyme#PC00260 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489 CIOIN|Ensembl=ENSCING00000009744.3|UniProtKB=H2XPN7 H2XPN7 PTHR14074:SF16 HELICASE WITH DEATH DOMAIN-RELATED ANTIVIRAL INNATE IMMUNE RESPONSE RECEPTOR RIG-I cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000006964.3|UniProtKB=Q4H3C8 Q4H3C8 Ci-Hox2 PTHR24333:SF13 HOMEO BOX HB9 LIKE A-RELATED HOMEOBOX DOMAIN-CONTAINING PROTEIN homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 CIOIN|Ensembl=ENSCING00000004778.3|UniProtKB=F6PLW6 F6PLW6 PTHR24320:SF226 RETINOL DEHYDROGENASE RETINOL DEHYDROGENASE 11 dehydrogenase#PC00092;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000008227.3|UniProtKB=F6RDK2 F6RDK2 PTHR16305:SF28 TESTICULAR SOLUBLE ADENYLYL CYCLASE GUANYLATE CYCLASE DOMAIN-CONTAINING PROTEIN adenylate cyclase activity#GO:0004016;lyase activity#GO:0016829;cyclase activity#GO:0009975;phosphorus-oxygen lyase activity#GO:0016849;catalytic activity#GO:0003824 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 Metabotropic glutamate receptor group III pathway#P00039>AC#P01043;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>AC#P01082 CIOIN|Ensembl=ENSCING00000020462.1|UniProtKB=H2Y0Y0 H2Y0Y0 PTHR21275:SF1 RWD DOMAIN-CONTAINING PROTEIN 4 RWD DOMAIN-CONTAINING PROTEIN 4 CIOIN|Ensembl=ENSCING00000024984.1|UniProtKB=H2Y1I9 H2Y1I9 PTHR21196:SF1 U7 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM10 U7 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM10 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;snRNA binding#GO:0017069;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;mRNA 3'-end processing#GO:0031124;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;mRNA processing#GO:0006397;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear body#GO:0016604;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 CIOIN|Ensembl=ENSCING00000004258.3|UniProtKB=F6YFR8 F6YFR8 PTHR13148:SF0 PER1-RELATED POST-GPI ATTACHMENT TO PROTEINS FACTOR 3 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;phospholipid biosynthetic process#GO:0008654;macromolecule modification#GO:0043412;organophosphate biosynthetic process#GO:0090407;phosphatidylinositol biosynthetic process#GO:0006661;glycolipid metabolic process#GO:0006664;protein modification process#GO:0036211;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;lipid biosynthetic process#GO:0008610;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;protein lipidation#GO:0006497;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;glycerolipid biosynthetic process#GO:0045017;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;glycerophospholipid metabolic process#GO:0006650;phosphatidylinositol metabolic process#GO:0046488;organic substance biosynthetic process#GO:1901576;liposaccharide metabolic process#GO:1903509;cellular process#GO:0009987;GPI anchor metabolic process#GO:0006505;membrane lipid biosynthetic process#GO:0046467;lipoprotein biosynthetic process#GO:0042158;primary metabolic process#GO:0044238;GPI anchor biosynthetic process#GO:0006506;carbohydrate derivative biosynthetic process#GO:1901137;membrane lipid metabolic process#GO:0006643;glycerophospholipid biosynthetic process#GO:0046474;glycolipid biosynthetic process#GO:0009247;organophosphate metabolic process#GO:0019637;lipoprotein metabolic process#GO:0042157;cellular lipid metabolic process#GO:0044255 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000015824.2|UniProtKB=F6RVH7 F6RVH7 LOC100179010 PTHR36978:SF4 P-LOOP CONTAINING NUCLEOTIDE TRIPHOSPHATE HYDROLASE P-LOOP CONTAINING NUCLEOSIDE TRIPHOSPHATE HYDROLASE PROTEIN metabolite interconversion enzyme#PC00262;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000006505.3|UniProtKB=A0A1W2WEL3 A0A1W2WEL3 LOC100180659 PTHR43601:SF3 THIOREDOXIN, MITOCHONDRIAL THIOREDOXIN, MITOCHONDRIAL homeostatic process#GO:0042592;cellular homeostasis#GO:0019725 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 Hypoxia response via HIF activation#P00030>Thioredoxin#P00825 CIOIN|Ensembl=ENSCING00000023571.1|UniProtKB=H2XQB4 H2XQB4 PTHR43903:SF28 NEUROLIGIN NEUROLIGIN 3, ISOFORM B cell adhesion molecule#PC00069 CIOIN|Ensembl=ENSCING00000024577.1|UniProtKB=H2XTN0 H2XTN0 PTHR18359:SF0 WD-REPEAT PROTEIN-RELATED U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 18 HOMOLOG membrane-enclosed lumen#GO:0031974;small-subunit processome#GO:0032040;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513;90S preribosome#GO:0030686 CIOIN|Ensembl=ENSCING00000000207.3|UniProtKB=F6VSV8 F6VSV8 PTHR10283:SF82 SOLUTE CARRIER FAMILY 13 MEMBER SOLUTE CARRIER FAMILY 13 MEMBER 2 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 localization#GO:0051179;establishment of localization#GO:0051234;cellular process#GO:0009987;transmembrane transport#GO:0055085;transport#GO:0006810 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000022146.1|UniProtKB=H2XMJ9 H2XMJ9 PTHR11360:SF284 MONOCARBOXYLATE TRANSPORTER EG:103B4.3 PROTEIN-RELATED transporter#PC00227 CIOIN|Ensembl=ENSCING00000006054.3|UniProtKB=F6ZZF2 F6ZZF2 LOC100177066 PTHR11561:SF0 PHOSPHOENOLPYRUVATE CARBOXYKINASE PHOSPHOENOLPYRUVATE CARBOXYKINASE [GTP]-RELATED cation binding#GO:0043169;carboxy-lyase activity#GO:0016831;carbon-carbon lyase activity#GO:0016830;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;transition metal ion binding#GO:0046914;metal ion binding#GO:0046872;lyase activity#GO:0016829;ion binding#GO:0043167 dicarboxylic acid metabolic process#GO:0043648;alcohol biosynthetic process#GO:0046165;lipid catabolic process#GO:0016042;response to extracellular stimulus#GO:0009991;acylglycerol metabolic process#GO:0006639;lipid biosynthetic process#GO:0008610;neutral lipid metabolic process#GO:0006638;triglyceride biosynthetic process#GO:0019432;carboxylic acid catabolic process#GO:0046395;cellular lipid catabolic process#GO:0044242;organic substance metabolic process#GO:0071704;organic hydroxy compound metabolic process#GO:1901615;oxoacid metabolic process#GO:0043436;response to oxygen-containing compound#GO:1901700;cellular response to organic substance#GO:0071310;cellular metabolic process#GO:0044237;alcohol metabolic process#GO:0006066;intracellular chemical homeostasis#GO:0055082;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;hexose biosynthetic process#GO:0019319;organic acid catabolic process#GO:0016054;response to glucose#GO:0009749;small molecule catabolic process#GO:0044282;response to stress#GO:0006950;small molecule biosynthetic process#GO:0044283;carbohydrate homeostasis#GO:0033500;small molecule metabolic process#GO:0044281;monocarboxylic acid catabolic process#GO:0072329;lipid metabolic process#GO:0006629;monosaccharide metabolic process#GO:0005996;response to lipid#GO:0033993;organic hydroxy compound biosynthetic process#GO:1901617;biosynthetic process#GO:0009058;cellular homeostasis#GO:0019725;cellular response to oxygen-containing compound#GO:1901701;glycerolipid metabolic process#GO:0046486;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carbohydrate metabolic process#GO:0005975;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;response to organic substance#GO:0010033;carbohydrate biosynthetic process#GO:0016051;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;triglyceride metabolic process#GO:0006641;glycerolipid biosynthetic process#GO:0045017;glucose homeostasis#GO:0042593;homeostatic process#GO:0042592;cellular biosynthetic process#GO:0044249;response to nutrient levels#GO:0031667;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;chemical homeostasis#GO:0048878;glucose metabolic process#GO:0006006;fatty acid catabolic process#GO:0009062;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;intracellular glucose homeostasis#GO:0001678;fatty acid metabolic process#GO:0006631;response to chemical#GO:0042221;response to starvation#GO:0042594;hexose metabolic process#GO:0019318;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 kinase#PC00137 Pyruvate metabolism#P02772>Phosphoenolpyruvate Carboxykinase#P03135 CIOIN|Ensembl=ENSCING00000008932.3|UniProtKB=F6QA40 F6QA40 LOC101243454 PTHR31395:SF23 SHISA GEO05642P1 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000004270.1|UniProtKB=F6UHC9 F6UHC9 LOC100182630 PTHR15614:SF2 INTRAFLAGELLAR TRANSPORT PROTEIN 81 HOMOLOG INTRAFLAGELLAR TRANSPORT PROTEIN 81 HOMOLOG cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 cilium organization#GO:0044782;cellular localization#GO:0051641;cell projection organization#GO:0030030;transport#GO:0006810;microtubule-based movement#GO:0007018;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;transport along microtubule#GO:0010970;intraciliary transport#GO:0042073;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;microtubule-based transport#GO:0099111;establishment of localization#GO:0051234;microtubule-based process#GO:0007017;organelle organization#GO:0006996;cytoskeleton-dependent intracellular transport#GO:0030705;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;protein-containing complex localization#GO:0031503 microtubule organizing center#GO:0005815;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intraciliary transport particle B#GO:0030992;microtubule cytoskeleton#GO:0015630;ciliary basal body#GO:0036064;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;cell projection#GO:0042995;cilium#GO:0005929;intraciliary transport particle#GO:0030990 CIOIN|Ensembl=ENSCING00000024930.1|UniProtKB=H2XQC0 H2XQC0 LOC100186879 PTHR13512:SF2 MEDIATOR COMPLEX SUBUNIT 28 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 28 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mediator complex#GO:0016592;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622 general transcription factor#PC00259 CIOIN|Ensembl=ENSCING00000006091.3|UniProtKB=F6YXJ6 F6YXJ6 LOC100176574 PTHR12669:SF12 EUKARYOTIC TRANSLATION INITIATION FACTOR 4E-BINDING PROTEIN EUKARYOTIC TRANSLATION INITIATION FACTOR 4E-BINDING PROTEIN translation initiation factor binding#GO:0031369;protein binding#GO:0005515;binding#GO:0005488 negative regulation of gene expression#GO:0010629;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;negative regulation of biosynthetic process#GO:0009890;regulation of amide metabolic process#GO:0034248;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;regulation of translational initiation#GO:0006446;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of translation#GO:0017148;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;post-transcriptional regulation of gene expression#GO:0010608;biological regulation#GO:0065007;regulation of translation#GO:0006417;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 translation initiation factor#PC00224;translation factor#PC00223;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000021870.1|UniProtKB=Q1RLA1 Q1RLA1 Ci-ZF(C2H2)-125 PTHR24404:SF114 ZINC FINGER PROTEIN KLUMPFUSS, ISOFORM B-RELATED C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 CIOIN|Ensembl=ENSCING00000006791.3|UniProtKB=F6VDV2 F6VDV2 PTHR11255:SF109 DIACYLGLYCEROL KINASE DIACYLGLYCEROL KINASE ETA transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301;lipid kinase activity#GO:0001727 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 transferase#PC00220;kinase#PC00137;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000010263.3|UniProtKB=F6QB69 F6QB69 PTHR10725:SF78 THAP DOMAIN-CONTAINING PROTEIN 9 DNA TRANSPOSASE THAP9 CIOIN|Ensembl=ENSCING00000001892.2|UniProtKB=F7AKR7 F7AKR7 LOC100186357 PTHR46780:SF21 PROTEIN EVA-1 ADHESION G PROTEIN-COUPLED RECEPTOR L3-RELATED CIOIN|Ensembl=ENSCING00000018957.1|UniProtKB=H2Y2R0 H2Y2R0 PTHR20003:SF7 GLYCOPROTEIN-RELATED SGNH DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000019053.1|UniProtKB=H2Y0K9 H2Y0K9 LOC100181881 PTHR22883:SF405 ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN PALMITOYLTRANSFERASE palmitoyltransferase activity#GO:0016409;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular localization#GO:0051641;macromolecule localization#GO:0033036;macromolecule modification#GO:0043412;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;biosynthetic process#GO:0009058;establishment of protein localization#GO:0045184;establishment of protein localization to membrane#GO:0090150;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;protein palmitoylation#GO:0018345;protein metabolic process#GO:0019538;protein lipidation#GO:0006497;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;localization within membrane#GO:0051668;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein localization to membrane#GO:0072657;organonitrogen compound biosynthetic process#GO:1901566;protein targeting#GO:0006605;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;protein acylation#GO:0043543;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;lipoprotein biosynthetic process#GO:0042158;protein localization#GO:0008104;primary metabolic process#GO:0044238;localization#GO:0051179;protein targeting to membrane#GO:0006612;cellular macromolecule localization#GO:0070727;lipoprotein metabolic process#GO:0042157 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000005294.3|UniProtKB=F6TV83 F6TV83 PTHR45807:SF7 TYROSINE-PROTEIN KINASE HOPSCOTCH TYROSINE-PROTEIN KINASE HOPSCOTCH non-receptor tyrosine protein kinase#PC00168 CIOIN|Ensembl=ENSCING00000008637.3|UniProtKB=F7AGY9 F7AGY9 LOC100187524 PTHR11785:SF512 AMINO ACID TRANSPORTER SOBREMESA, ISOFORM B L-amino acid transmembrane transporter activity#GO:0015179;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;amino acid transmembrane transporter activity#GO:0015171;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215;organic acid transmembrane transporter activity#GO:0005342 localization#GO:0051179;organic substance transport#GO:0071702;amino acid transmembrane transport#GO:0003333;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;amino acid transport#GO:0006865;organic anion transport#GO:0015711;organic acid transport#GO:0015849;transport#GO:0006810;nitrogen compound transport#GO:0071705;organic acid transmembrane transport#GO:1903825;carboxylic acid transport#GO:0046942;cellular process#GO:0009987;carboxylic acid transmembrane transport#GO:1905039 transporter#PC00227 CIOIN|Ensembl=ENSCING00000022631.1|UniProtKB=H2XQR0 H2XQR0 PTHR24255:SF31 COMPLEMENT COMPONENT 1, S SUBCOMPONENT-RELATED CUBILIN-LIKE PROTEIN hydrolase activity#GO:0016787;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 serine protease#PC00203;protease#PC00190 CIOIN|Ensembl=ENSCING00000002150.3|UniProtKB=F6W4G9 F6W4G9 PTHR24012:SF918 RNA BINDING PROTEIN RRM DOMAIN-CONTAINING PROTEIN nucleic acid binding#GO:0003676;single-stranded RNA binding#GO:0003727;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159;mRNA binding#GO:0003729;poly(A) binding#GO:0008143;mRNA 3'-UTR binding#GO:0003730 supramolecular complex#GO:0099080;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic ribonucleoprotein granule#GO:0036464;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein complex#GO:1990904;ribonucleoprotein granule#GO:0035770;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;cytoplasmic stress granule#GO:0010494 RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000020318.1|UniProtKB=H2XZ97 H2XZ97 ci-zf(c3h)-7 PTHR13119:SF12 ZINC FINGER CCCH DOMAIN-CONTAINING PROTEI PROTEIN SUPPRESSOR OF SABLE membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 zinc finger transcription factor#PC00244 CIOIN|Ensembl=ENSCING00000022318.1|UniProtKB=H2XZ50 H2XZ50 PTHR19818:SF139 ZINC FINGER PROTEIN ZIC AND GLI PAIR-RULE PROTEIN ODD-PAIRED sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 CIOIN|Ensembl=ENSCING00000002335.3|UniProtKB=Q7YT75 Q7YT75 LOC448957 PTHR24072:SF169 RHO FAMILY GTPASE RAS-RELATED C3 BOTULINUM TOXIN SUBSTRATE 2 GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;enzyme binding#GO:0019899;ribonucleoside triphosphate phosphatase activity#GO:0017111;kinase binding#GO:0019900;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;protein kinase binding#GO:0019901;anion binding#GO:0043168;ion binding#GO:0043167 establishment or maintenance of cell polarity#GO:0007163;regulation of anatomical structure morphogenesis#GO:0022603;regulation of organelle organization#GO:0033043;regulation of cellular component organization#GO:0051128;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of cytoskeleton organization#GO:0051493;regulation of cell shape#GO:0008360;regulation of biological quality#GO:0065008;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;cortical cytoskeleton organization#GO:0030865;biological regulation#GO:0065007;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;regulation of actin filament-based process#GO:0032970 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 small GTPase#PC00208 T cell activation#P00053>rac#P01324;Huntington disease#P00029>Rac#P00775;p38 MAPK pathway#P05918>Rac#P06021;Cytoskeletal regulation by Rho GTPase#P00016>Rac#P00523;EGF receptor signaling pathway#P00018>Rac#P00564;Axon guidance mediated by semaphorins#P00007>Rac#P00340;VEGF signaling pathway#P00056>Rac#P01421;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Cdc42#P00834;Ras Pathway#P04393>Rac#P04559;Axon guidance mediated by netrin#P00009>Rac#P00366;B cell activation#P00010>Rac#P00385;Integrin signalling pathway#P00034>Rac#P00927;Axon guidance mediated by Slit/Robo#P00008>Rac#P00354;FGF signaling pathway#P00021>Rac#P00645 CIOIN|Ensembl=ENSCING00000008595.3|UniProtKB=Q1RLD5 Q1RLD5 Ci-ZF(CCHC)-12 PTHR12942:SF2 STEP II SPLICING FACTOR SLU7 PRE-MRNA-SPLICING FACTOR SLU7 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA splicing factor#PC00148;RNA processing factor#PC00147;RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000008742.3|UniProtKB=F6T120 F6T120 PTHR21581:SF6 D-ALANYL-D-ALANINE CARBOXYPEPTIDASE TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 12 serine protease#PC00203 CIOIN|Ensembl=ENSCING00000004994.3|UniProtKB=F6X9B1 F6X9B1 PTHR23113:SF252 GUANINE NUCLEOTIDE EXCHANGE FACTOR RAS GUANYL-RELEASING PROTEIN 3 nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;small GTPase-mediated signal transduction#GO:0007264;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;Ras protein signal transduction#GO:0007265;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 CIOIN|Ensembl=ENSCING00000024649.1|UniProtKB=H2XV20 H2XV20 PTHR44329:SF291 SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED PROTEIN KINASE DOMAIN-CONTAINING PROTEIN MAP kinase kinase kinase activity#GO:0004709;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000013683.2|UniProtKB=F6PXD8 F6PXD8 PTHR14741:SF32 S-ADENOSYLMETHIONINE-DEPENDENT METHYLTRANSFERASE RELATED TRIMETHYLGUANOSINE SYNTHASE RNA metabolism protein#PC00031;RNA methyltransferase#PC00033 CIOIN|Ensembl=ENSCING00000001384.3|UniProtKB=Q9NDQ5 Q9NDQ5 Ci-Not3 PTHR11214:SF283 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE N-ACETYLLACTOSAMINIDE BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE 4-LIKE transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;protein O-linked glycosylation#GO:0006493;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 bounding membrane of organelle#GO:0098588;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;Golgi membrane#GO:0000139;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111 CIOIN|Ensembl=ENSCING00000008241.3|UniProtKB=F6R4U4 F6R4U4 PTHR12002:SF116 CLAUDIN CLAUDIN-11-LIKE cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cell-cell junction organization#GO:0045216;cellular component biogenesis#GO:0044085;cell-cell junction assembly#GO:0007043;cell junction organization#GO:0034330;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;cell adhesion#GO:0007155;cellular process#GO:0009987 tight junction#GO:0070160;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cell junction#GO:0030054;bicellular tight junction#GO:0005923;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;apical junction complex#GO:0043296;plasma membrane#GO:0005886 cell junction protein#PC00070;tight junction#PC00214 CIOIN|Ensembl=ENSCING00000010125.3|UniProtKB=F6PID9 F6PID9 PTHR11771:SF153 LIPOXYGENASE LIPOXYGENASE DOMAIN-CONTAINING PROTEIN oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;dioxygenase activity#GO:0051213 lipid metabolic process#GO:0006629;lipid oxidation#GO:0034440;cellular metabolic process#GO:0044237;lipid modification#GO:0030258;cellular lipid metabolic process#GO:0044255;cellular process#GO:0009987;metabolic process#GO:0008152;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704 oxygenase#PC00177;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000008085.3|UniProtKB=F6Z6J9 F6Z6J9 PTHR11844:SF25 METALLOPROTEASE INHIBITOR NTR DOMAIN-CONTAINING PROTEIN peptidase inhibitor activity#GO:0030414;protease binding#GO:0002020;binding#GO:0005488;molecular function regulator activity#GO:0098772;enzyme binding#GO:0019899;protein binding#GO:0005515;peptidase regulator activity#GO:0061134;enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;endopeptidase regulator activity#GO:0061135;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234 negative regulation of hydrolase activity#GO:0051346;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;regulation of catabolic process#GO:0009894;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of protein catabolic process#GO:0042177;regulation of protein catabolic process#GO:0042176;regulation of catalytic activity#GO:0050790;regulation of biological process#GO:0050789;regulation of molecular function#GO:0065009;regulation of hydrolase activity#GO:0051336;negative regulation of cellular process#GO:0048523;response to organic substance#GO:0010033;regulation of proteolysis#GO:0030162;negative regulation of endopeptidase activity#GO:0010951;negative regulation of peptidase activity#GO:0010466;negative regulation of cellular catabolic process#GO:0031330;negative regulation of metabolic process#GO:0009892;negative regulation of proteolysis#GO:0045861;regulation of cellular catabolic process#GO:0031329;negative regulation of protein metabolic process#GO:0051248;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;negative regulation of catabolic process#GO:0009895;regulation of macromolecule metabolic process#GO:0060255;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of endopeptidase activity#GO:0052548;regulation of peptidase activity#GO:0052547;negative regulation of catalytic activity#GO:0043086;regulation of metabolic process#GO:0019222;negative regulation of molecular function#GO:0044092;regulation of cellular metabolic process#GO:0031323 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;extracellular space#GO:0005615;extracellular region#GO:0005576 protease inhibitor#PC00191 CIOIN|Ensembl=ENSCING00000004153.3|UniProtKB=F6TUR1 F6TUR1 PTHR45815:SF3 PROTEIN DISULFIDE-ISOMERASE A6 PROTEIN DISULFIDE-ISOMERASE A6 protein-disulfide reductase activity#GO:0015035;disulfide oxidoreductase activity#GO:0015036;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;response to stress#GO:0006950;response to endoplasmic reticulum stress#GO:0034976;cellular process#GO:0009987;cellular response to stress#GO:0033554 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;endoplasmic reticulum lumen#GO:0005788;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chaperone#PC00072 CIOIN|Ensembl=ENSCING00000023726.1|UniProtKB=H2XKM0 H2XKM0 PTHR13528:SF2 39S RIBOSOMAL PROTEIN L28, MITOCHONDRIAL LARGE RIBOSOMAL SUBUNIT PROTEIN BL28M structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 ribosomal protein#PC00202;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000005755.3|UniProtKB=F6PUK0 F6PUK0 LOC100178511 PTHR16116:SF5 ZINC FINGER PROTEIN 839 ZINC FINGER PROTEIN 839 CIOIN|Ensembl=ENSCING00000002142.3|UniProtKB=F6W5A6 F6W5A6 LOC100182887 PTHR31336:SF3 LIN37 HOMOLOG PROTEIN LIN-37 HOMOLOG CIOIN|Ensembl=ENSCING00000001762.3|UniProtKB=F6ZKS0 F6ZKS0 PTHR10676:SF352 DYNEIN HEAVY CHAIN FAMILY PROTEIN CYTOPLASMIC DYNEIN 2 HEAVY CHAIN 1 cytoskeletal motor activity#GO:0003774;microtubule motor activity#GO:0003777;protein binding#GO:0005515;ATP-dependent activity#GO:0140657;binding#GO:0005488 cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;cell projection organization#GO:0030030;transport#GO:0006810;microtubule-based movement#GO:0007018;plasma membrane bounded cell projection organization#GO:0120036;cilium movement involved in cell motility#GO:0060294;establishment of localization#GO:0051234;cytoskeleton-dependent intracellular transport#GO:0030705;cellular component assembly#GO:0022607;cilium assembly#GO:0060271;cilium or flagellum-dependent cell motility#GO:0001539;cellular component organization#GO:0016043;cell motility#GO:0048870;cellular process#GO:0009987;intraciliary retrograde transport#GO:0035721;transport along microtubule#GO:0010970;intraciliary transport#GO:0042073;cell projection assembly#GO:0030031;cilium movement#GO:0003341;organelle assembly#GO:0070925;localization#GO:0051179;cilium-dependent cell motility#GO:0060285;cellular component organization or biogenesis#GO:0071840;microtubule-based transport#GO:0099111;microtubule-based process#GO:0007017;organelle organization#GO:0006996;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;protein-containing complex localization#GO:0031503 axoneme#GO:0005930;catalytic complex#GO:1902494;cytoplasmic region#GO:0099568;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;microtubule associated complex#GO:0005875;non-membrane-bounded organelle#GO:0043228;motile cilium#GO:0031514;protein-containing complex#GO:0032991;9+2 motile cilium#GO:0097729;microtubule cytoskeleton#GO:0015630;ciliary plasm#GO:0097014;plasma membrane bounded cell projection cytoplasm#GO:0032838;membrane-bounded organelle#GO:0043227;dynein complex#GO:0030286;cell projection#GO:0042995;cytoskeleton#GO:0005856;cilium#GO:0005929;cytoplasmic dynein complex#GO:0005868 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 Huntington disease#P00029>Dynein complex#P00774 CIOIN|Ensembl=ENSCING00000020500.1|UniProtKB=H2XZF5 H2XZF5 PTHR10259:SF11 THIOPURINE S-METHYLTRANSFERASE THIOPURINE S-METHYLTRANSFERASE methyltransferase activity#GO:0008168;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757 methyltransferase#PC00155 CIOIN|Ensembl=ENSCING00000008796.3|UniProtKB=F6SCN2 F6SCN2 LOC100178529 PTHR11540:SF16 MALATE AND LACTATE DEHYDROGENASE MALATE DEHYDROGENASE, MITOCHONDRIAL oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 Pyruvate metabolism#P02772>Lactate Dehydrogenase#P03139 CIOIN|Ensembl=ENSCING00000011560.2|UniProtKB=F6TBP5 F6TBP5 LOC100183651 PTHR22802:SF379 C-TYPE LECTIN SUPERFAMILY MEMBER CHONDROITIN SULFATE PROTEOGLYCAN 2 ISOFORM X1 membrane traffic protein#PC00150 CIOIN|Ensembl=ENSCING00000012655.2|UniProtKB=F6URK3 F6URK3 PTHR10460:SF0 ABL INTERACTOR FAMILY MEMBER ABELSON INTERACTING PROTEIN, ISOFORM D scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000021435.1|UniProtKB=H2XVD4 H2XVD4 PTHR23292:SF46 LIPOPOLYSACCHARIDE-INDUCED TUMOR NECROSIS FACTOR-ALPHA FACTOR LIPOPOLYSACCHARIDE-INDUCED TUMOR NECROSIS FACTOR-ALPHA FACTOR HOMOLOG cation binding#GO:0043169;metal ion binding#GO:0046872;ion binding#GO:0043167;small molecule binding#GO:0036094;zinc ion binding#GO:0008270;binding#GO:0005488;transition metal ion binding#GO:0046914 bounding membrane of organelle#GO:0098588;lytic vacuole membrane#GO:0098852;endosome#GO:0005768;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuolar membrane#GO:0005774;late endosome membrane#GO:0031902;vacuole#GO:0005773;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endosome membrane#GO:0010008;lytic vacuole#GO:0000323;membrane#GO:0016020;side of membrane#GO:0098552;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;lysosomal membrane#GO:0005765;lysosome#GO:0005764;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle membrane#GO:0030659;late endosome#GO:0005770 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000004059.3|UniProtKB=F7B6E8 F7B6E8 LOC100178564 PTHR11692:SF0 BIFUNCTIONAL PURINE BIOSYNTHESIS PROTEIN PURH BIFUNCTIONAL PURINE BIOSYNTHESIS PROTEIN ATIC hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;purine ribonucleoside monophosphate metabolic process#GO:0009167;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;nucleotide biosynthetic process#GO:0009165;nucleoside monophosphate metabolic process#GO:0009123;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;IMP metabolic process#GO:0046040;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;purine nucleoside monophosphate metabolic process#GO:0009126;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;ribonucleoside monophosphate metabolic process#GO:0009161;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;IMP biosynthetic process#GO:0006188;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 De novo purine biosynthesis#P02738>AICAR transformylase#P02900;De novo purine biosynthesis#P02738>IMP cyclohydrolase#P02894 CIOIN|Ensembl=ENSCING00000002653.3|UniProtKB=F7AIP5 F7AIP5 zf(u1like)-8 PTHR44029:SF1 DNAJ HOMOLOG SUBFAMILY C MEMBER 21 DNAJ HOMOLOG SUBFAMILY C MEMBER 21 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 chaperone#PC00072 CIOIN|Ensembl=ENSCING00000020837.1|UniProtKB=H2XKP9 H2XKP9 PTHR45712:SF27 AGAP008170-PA LRRNT DOMAIN-CONTAINING PROTEIN extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 CIOIN|Ensembl=ENSCING00000004107.3|UniProtKB=F6XVV4 F6XVV4 PTHR11486:SF142 FIBROBLAST GROWTH FACTOR FIBROBLAST GROWTH FACTOR molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;binding#GO:0005488;growth factor activity#GO:0008083;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;growth factor receptor binding#GO:0070851;protein binding#GO:0005515;signaling receptor binding#GO:0005102;fibroblast growth factor receptor binding#GO:0005104 positive regulation of gene expression#GO:0010628;regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;positive regulation of cell population proliferation#GO:0008284;positive regulation of protein modification process#GO:0031401;regulation of intracellular signal transduction#GO:1902531;response to fibroblast growth factor#GO:0071774;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;regulation of cell migration#GO:0030334;anatomical structure morphogenesis#GO:0009653;regulation of signal transduction#GO:0009966;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;cellular developmental process#GO:0048869;cellular response to endogenous stimulus#GO:0071495;positive regulation of phosphorus metabolic process#GO:0010562;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;positive regulation of cell communication#GO:0010647;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;fibroblast growth factor receptor signaling pathway#GO:0008543;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;regulation of locomotion#GO:0040012;response to growth factor#GO:0070848;animal organ development#GO:0048513;regulation of signaling#GO:0023051;developmental process#GO:0032502;positive regulation of MAPK cascade#GO:0043410;positive regulation of response to stimulus#GO:0048584;positive regulation of biosynthetic process#GO:0009891;cell differentiation#GO:0030154;response to endogenous stimulus#GO:0009719;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of intracellular signal transduction#GO:1902533;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;signaling#GO:0023052;regulation of cell communication#GO:0010646;positive regulation of protein phosphorylation#GO:0001934;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;regulation of cell population proliferation#GO:0042127;regulation of cell motility#GO:2000145;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;cellular response to growth factor stimulus#GO:0071363;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;animal organ morphogenesis#GO:0009887;cellular response to fibroblast growth factor stimulus#GO:0044344 cytoplasm#GO:0005737;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576;intracellular anatomical structure#GO:0005622 intercellular signal molecule#PC00207;growth factor#PC00112 CIOIN|Ensembl=ENSCING00000024315.1|UniProtKB=H2XJH4 H2XJH4 PTHR14248:SF18 CYCLIN Y, ISOFORM A CYCLIN Y, ISOFORM A cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 CIOIN|Ensembl=ENSCING00000006815.3|UniProtKB=F6TZU9 F6TZU9 PTHR11472:SF41 DNA REPAIR DEAD HELICASE RAD3/XP-D SUBFAMILY MEMBER ATP-DEPENDENT DNA HELICASE DDX11-RELATED ATP-dependent activity, acting on DNA#GO:0008094;catalytic activity, acting on a nucleic acid#GO:0140640;DNA helicase activity#GO:0003678;catalytic activity, acting on DNA#GO:0140097;helicase activity#GO:0004386;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824 DNA conformation change#GO:0071103;cellular component organization or biogenesis#GO:0071840;sister chromatid cohesion#GO:0007062;organelle organization#GO:0006996;chromosome organization#GO:0051276;DNA duplex unwinding#GO:0032508;cell cycle process#GO:0022402;cell cycle#GO:0007049;cellular component organization#GO:0016043;cellular process#GO:0009987;DNA geometric change#GO:0032392 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA helicase#PC00011;DNA metabolism protein#PC00009 CIOIN|Ensembl=ENSCING00000006338.3|UniProtKB=Q4H2W4 Q4H2W4 Ci-PUR-alpha_beta_gamma PTHR12611:SF0 PUR-TRANSCRIPTIONAL ACTIVATOR PURINE-RICH BINDING PROTEIN-ALPHA, ISOFORM B sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218 CIOIN|Ensembl=ENSCING00000022604.1|UniProtKB=H2XNN8 H2XNN8 PTHR48078:SF2 THREONINE DEHYDRATASE, MITOCHONDRIAL-RELATED CATABOLIC L-SERINE_THREONINE DEHYDRATASE lyase activity#GO:0016829;catalytic activity#GO:0003824 branched-chain amino acid metabolic process#GO:0009081;organonitrogen compound catabolic process#GO:1901565;biosynthetic process#GO:0009058;branched-chain amino acid biosynthetic process#GO:0009082;carboxylic acid biosynthetic process#GO:0046394;amino acid catabolic process#GO:0009063;nitrogen compound metabolic process#GO:0006807;alpha-amino acid metabolic process#GO:1901605;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;L-amino acid metabolic process#GO:0170033;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248;organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;proteinogenic amino acid metabolic process#GO:0170039;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;alpha-amino acid biosynthetic process#GO:1901607;aspartate family amino acid metabolic process#GO:0009066;small molecule biosynthetic process#GO:0044283;carboxylic acid metabolic process#GO:0019752;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281 dehydratase#PC00091;lyase#PC00144 CIOIN|Ensembl=ENSCING00000007929.3|UniProtKB=F6ZSF5 F6ZSF5 LOC100185977 PTHR10015:SF465 HEAT SHOCK TRANSCRIPTION FACTOR HSF-TYPE DNA-BINDING DOMAIN-CONTAINING PROTEIN DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 CIOIN|Ensembl=ENSCING00000008261.3|UniProtKB=F6QU80 F6QU80 PTHR34252:SF1 UPF0705 PROTEIN C11ORF49 CENTRIOLAR SATELLITE-ASSOCIATED TUBULIN POLYGLUTAMYLASE COMPLEX REGULATOR 1 CIOIN|Ensembl=ENSCING00000021953.1|UniProtKB=H2XTQ3 H2XTQ3 LOC100178572 PTHR20978:SF0 SPLICING FACTOR 3B SUBUNIT 5 SPLICING FACTOR 3B SUBUNIT 5 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;spliceosomal snRNP complex#GO:0097525;protein-containing complex#GO:0032991;small nuclear ribonucleoprotein complex#GO:0030532;U2 snRNP#GO:0005686;membrane-bounded organelle#GO:0043227;precatalytic spliceosome#GO:0071011;Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513 RNA splicing factor#PC00148;RNA processing factor#PC00147;RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000021502.1|UniProtKB=H2Y0Q2 H2Y0Q2 LOC104266887 PTHR24068:SF526 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2D 4 LIKE 1 ubiquitin-like protein conjugating enzyme activity#GO:0061650;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;ubiquitin-like protein ligase binding#GO:0044389;enzyme binding#GO:0019899;ubiquitin conjugating enzyme activity#GO:0061631;protein binding#GO:0005515;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin protein ligase binding#GO:0031625 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein K48-linked ubiquitination#GO:0070936;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein polyubiquitination#GO:0000209;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 Ubiquitin proteasome pathway#P00060>E2#P01491 CIOIN|Ensembl=ENSCING00000002788.3|UniProtKB=F6ZYD2 F6ZYD2 LOC100183397 PTHR46829:SF1 STERILE ALPHA MOTIF DOMAIN-CONTAINING PROTEIN 15 STERILE ALPHA MOTIF DOMAIN-CONTAINING PROTEIN 15 CIOIN|Ensembl=ENSCING00000003516.3|UniProtKB=F7BHN6 F7BHN6 zf(c3h)-9 PTHR14398:SF0 RNA RECOGNITION RRM/RNP DOMAIN ZINC FINGER PROTEIN SWM nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000006808.3|UniProtKB=F6UMP0 F6UMP0 PTHR12225:SF0 ADHESION REGULATING MOLECULE 1 110 KDA CELL MEMBRANE GLYCOPROTEIN PROTEASOMAL UBIQUITIN RECEPTOR ADRM1 peptidase activator activity#GO:0016504;proteasome binding#GO:0070628;molecular function activator activity#GO:0140677;binding#GO:0005488;molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047;peptidase regulator activity#GO:0061134;protein-containing complex binding#GO:0044877;endopeptidase regulator activity#GO:0061135;enzyme regulator activity#GO:0030234 peptidase complex#GO:1905368;protein-containing complex#GO:0032991;proteasome accessory complex#GO:0022624;proteasome regulatory particle#GO:0005838;catalytic complex#GO:1902494;proteasome regulatory particle, lid subcomplex#GO:0008541;proteasome complex#GO:0000502;endopeptidase complex#GO:1905369;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000019683.1|UniProtKB=H2XRF8 H2XRF8 PTHR33862:SF3 OROFACIAL CLEFT 1 CANDIDATE GENE 1 PROTEIN OROFACIAL CLEFT 1 CANDIDATE GENE 1 PROTEIN CIOIN|Ensembl=ENSCING00000021506.1|UniProtKB=H2XW15 H2XW15 PTHR19444:SF13 UNC-93 RELATED PROTEIN UNC-93 HOMOLOG A membrane-bound signaling molecule#PC00152 CIOIN|Ensembl=ENSCING00000002027.3|UniProtKB=F6Z3D0 F6Z3D0 PTHR12411:SF992 CYSTEINE PROTEASE FAMILY C1-RELATED CATHEPSIN F cysteine-type peptidase activity#GO:0008234;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197 macromolecule catabolic process#GO:0009057;nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;proteolysis#GO:0006508;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;catabolic process#GO:0009056;organonitrogen compound catabolic process#GO:1901565;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;primary metabolic process#GO:0044238 cytoplasm#GO:0005737;lysosome#GO:0005764;intracellular membrane-bounded organelle#GO:0043231;extracellular region#GO:0005576;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;organelle#GO:0043226;lytic vacuole#GO:0000323;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cysteine protease#PC00081;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000003086.3|UniProtKB=F6RCY1 F6RCY1 PTHR10290:SF3 DNA TOPOISOMERASE I DNA TOPOISOMERASE 1 DNA topoisomerase#PC00017 DNA replication#P00017>Top#P00530;DNA replication#P00017>DNA Topisomerase#P00536 CIOIN|Ensembl=ENSCING00000017035.2|UniProtKB=A0A1W5B6T4 A0A1W5B6T4 LOC100185755 PTHR11991:SF0 TRANSLATIONALLY CONTROLLED TUMOR PROTEIN-RELATED TRANSLATIONALLY-CONTROLLED TUMOR PROTEIN cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 CIOIN|Ensembl=ENSCING00000010138.3|UniProtKB=F6PI87 F6PI87 PTHR12606:SF141 SENTRIN/SUMO-SPECIFIC PROTEASE GH15225P-RELATED protease#PC00190 CIOIN|Ensembl=ENSCING00000016347.2|UniProtKB=F6VGZ6 F6VGZ6 PTHR18934:SF109 ATP-DEPENDENT RNA HELICASE ATP-DEPENDENT RNA HELICASE DHX15 HOMOLOG nucleic acid binding#GO:0003676;RNA binding#GO:0003723;helicase activity#GO:0004386;ATP-dependent activity#GO:0140657;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;catalytic activity, acting on a nucleic acid#GO:0140640 cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 RNA helicase#PC00032 CIOIN|Ensembl=ENSCING00000018963.1|UniProtKB=H2Y1Q1 H2Y1Q1 PTHR10218:SF302 GTP-BINDING PROTEIN ALPHA SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN ALPHA-5 SUBUNIT GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;ribonucleoside triphosphate phosphatase activity#GO:0017111;G protein-coupled receptor binding#GO:0001664;signaling receptor binding#GO:0005102 regulation of biological process#GO:0050789;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cytoplasm#GO:0005737;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;cytoplasmic side of plasma membrane#GO:0009898;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622;extrinsic component of membrane#GO:0019898 heterotrimeric G-protein#PC00117;G-protein#PC00020 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Galphai#P00828;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Galphai/q#P00873 CIOIN|Ensembl=ENSCING00000003311.3|UniProtKB=F6TBE2 F6TBE2 PTHR12000:SF42 HEMOGLOBINASE FAMILY MEMBER LEGUMAIN cysteine-type peptidase activity#GO:0008234;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197 macromolecule catabolic process#GO:0009057;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;protein processing#GO:0016485;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cysteine protease#PC00081;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000008561.3|UniProtKB=F6X0V6 F6X0V6 PTHR12969:SF7 NGD5/OSM-6/IFT52 INTRAFLAGELLAR TRANSPORT PROTEIN 52 HOMOLOG CIOIN|Ensembl=ENSCING00000012311.2|UniProtKB=F7AVR1 F7AVR1 PTHR24340:SF35 HOMEOBOX PROTEIN NKX HGTX, ISOFORM C sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 CIOIN|Ensembl=ENSCING00000004186.3|UniProtKB=F7B5L6 F7B5L6 PTHR10665:SF0 RECOMBINING BINDING PROTEIN SUPPRESSOR OF HAIRLESS SUPPRESSOR OF HAIRLESS PROTEIN cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 Rel homology transcription factor#PC00252;immunoglobulin fold transcription factor#PC00251 Notch signaling pathway#P00045>Su(H)#P01101;Alzheimer disease-presenilin pathway#P00004>CSL#P00158;Angiogenesis#P00005>CSL#P00233 CIOIN|Ensembl=ENSCING00000013245.2|UniProtKB=F6SGC2 F6SGC2 PTHR15641:SF1 ELONGATOR COMPLEX PROTEIN 5 ELONGATOR COMPLEX PROTEIN 5 tRNA binding#GO:0000049;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA modification#GO:0009451;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;tRNA modification#GO:0006400;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 elongator holoenzyme complex#GO:0033588;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000021101.1|UniProtKB=A0A1W3JGN6 A0A1W3JGN6 LOC100185744 PTHR23339:SF98 TYROSINE SPECIFIC PROTEIN PHOSPHATASE AND DUAL SPECIFICITY PROTEIN PHOSPHATASE PRL-1 PHOSPHATASE protein phosphatase#PC00195;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000024100.1|UniProtKB=H2XZL8 H2XZL8 PTHR23338:SF18 SMALL NUCLEAR RIBONUCLEOPROTEIN SM SMALL NUCLEAR RIBONUCLEOPROTEIN SM D1 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;RNA processing#GO:0006396;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;protein-RNA complex assembly#GO:0022618;organic cyclic compound metabolic process#GO:1901360;mRNA metabolic process#GO:0016071;nitrogen compound metabolic process#GO:0006807;spliceosomal snRNP assembly#GO:0000387;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular component assembly#GO:0022607;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;protein-containing complex organization#GO:0043933;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;ribonucleoprotein complex biogenesis#GO:0022613;mRNA processing#GO:0006397;protein-RNA complex organization#GO:0071826;RNA splicing, via transesterification reactions#GO:0000375 catalytic step 2 spliceosome#GO:0071013;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;U1 snRNP#GO:0005685;U2-type spliceosomal complex#GO:0005684;cellular anatomical entity#GO:0110165;organelle#GO:0043226;U4 snRNP#GO:0005687;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;U5 snRNP#GO:0005682;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;SMN-Sm protein complex#GO:0034719;ribonucleoprotein complex#GO:1990904;spliceosomal snRNP complex#GO:0097525;small nuclear ribonucleoprotein complex#GO:0030532;protein-containing complex#GO:0032991;pICln-Sm protein complex#GO:0034715;U2 snRNP#GO:0005686;spliceosomal tri-snRNP complex#GO:0097526;precatalytic spliceosome#GO:0071011;membrane-bounded organelle#GO:0043227;Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513 RNA splicing factor#PC00148;RNA processing factor#PC00147 CIOIN|Ensembl=ENSCING00000006473.3|UniProtKB=F6Q548 F6Q548 PTHR13158:SF5 FAMILY NOT NAMED NAD KINASE 2, MITOCHONDRIAL transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;pyridine nucleotide metabolic process#GO:0019362;nicotinamide nucleotide metabolic process#GO:0046496;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;primary metabolic process#GO:0044238;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;pyridine-containing compound metabolic process#GO:0072524;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 CIOIN|Ensembl=ENSCING00000023083.1|UniProtKB=A0A1W2WQ35 A0A1W2WQ35 LOC100185367 PTHR13691:SF16 RIBOSOMAL PROTEIN L2 LARGE RIBOSOMAL SUBUNIT PROTEIN UL2 structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;structural molecule activity#GO:0005198;binding#GO:0005488;organic cyclic compound binding#GO:0097159 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cytoplasmic translation#GO:0002181;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic large ribosomal subunit#GO:0022625;large ribosomal subunit#GO:0015934;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000011548.2|UniProtKB=F6TC72 F6TC72 LOC100176846 PTHR34833:SF1 GENE, 17359-RELATED GENE, 17359-RELATED CIOIN|Ensembl=ENSCING00000005950.4|UniProtKB=F6YFB9 F6YFB9 PTHR10724:SF10 30S RIBOSOMAL PROTEIN S1 S1 RNA-BINDING DOMAIN-CONTAINING PROTEIN 1 structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;RNA binding#GO:0003723;structural molecule activity#GO:0005198;binding#GO:0005488;organic cyclic compound binding#GO:0097159 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;translation#GO:0006412;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 ribosomal protein#PC00202;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000021861.1|UniProtKB=H2Y2K6 H2Y2K6 LOC100177275 PTHR43161:SF24 SORBITOL DEHYDROGENASE SORBITOL DEHYDROGENASE oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 organic hydroxy compound metabolic process#GO:1901615;small molecule catabolic process#GO:0044282;carbohydrate catabolic process#GO:0016052;catabolic process#GO:0009056;alcohol metabolic process#GO:0006066;organic substance catabolic process#GO:1901575;carbohydrate metabolic process#GO:0005975;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000002817.3|UniProtKB=F6WZA5 F6WZA5 PTHR23113:SF363 GUANINE NUCLEOTIDE EXCHANGE FACTOR PROTEIN SON OF SEVENLESS nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;small GTPase-mediated signal transduction#GO:0007264;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;Ras protein signal transduction#GO:0007265;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 FGF signaling pathway#P00021>SOS#P00641;Angiogenesis#P00005>SOS-1#P00193;Integrin signalling pathway#P00034>SOS#P00920;PDGF signaling pathway#P00047>SOS#P01159;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>SOS#P00883;EGF receptor signaling pathway#P00018>SOS#P00558;Ras Pathway#P04393>SOS#P04552 CIOIN|Ensembl=ENSCING00000004833.3|UniProtKB=F6TZ34 F6TZ34 LOC100185094 PTHR11153:SF8 SIDEROFLEXIN SIDEROFLEXIN-1 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 neutral amino acid transport#GO:0015804;transmembrane transport#GO:0055085;organic anion transport#GO:0015711;amino acid transport#GO:0006865;organic acid transport#GO:0015849;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942;cellular process#GO:0009987;carboxylic acid transmembrane transport#GO:1905039;mitochondrial transport#GO:0006839;localization#GO:0051179;organic substance transport#GO:0071702;amino acid transmembrane transport#GO:0003333;establishment of localization#GO:0051234;organic acid transmembrane transport#GO:1903825;mitochondrial transmembrane transport#GO:1990542 envelope#GO:0031975;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;organelle membrane#GO:0031090;organelle inner membrane#GO:0019866;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227 primary active transporter#PC00068;transporter#PC00227 CIOIN|Ensembl=ENSCING00000004814.3|UniProtKB=F6R999 F6R999 PTHR12323:SF0 SR-RELATED CTD ASSOCIATED FACTOR 6 CALCIUM HOMEOSTASIS ENDOPLASMIC RETICULUM PROTEIN inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;homeostatic process#GO:0042592;intracellular monoatomic ion homeostasis#GO:0006873;chemical homeostasis#GO:0048878;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;monoatomic ion homeostasis#GO:0050801 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;perinuclear region of cytoplasm#GO:0048471;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000012516.2|UniProtKB=F7BDU0 F7BDU0 PTHR46120:SF4 BETAINE--HOMOCYSTEINE S-METHYLTRANSFERASE 1 HCY-BINDING DOMAIN-CONTAINING PROTEIN methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824 organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;proteinogenic amino acid metabolic process#GO:0170039;sulfur compound metabolic process#GO:0006790;proteinogenic amino acid biosynthetic process#GO:0170038;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;aspartate family amino acid biosynthetic process#GO:0009067;alpha-amino acid biosynthetic process#GO:1901607;nitrogen compound metabolic process#GO:0006807;amino acid biosynthetic process#GO:0008652;alpha-amino acid metabolic process#GO:1901605;aspartate family amino acid metabolic process#GO:0009066;small molecule biosynthetic process#GO:0044283;L-amino acid biosynthetic process#GO:0170034;carboxylic acid metabolic process#GO:0019752;L-amino acid metabolic process#GO:0170033;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 methyltransferase#PC00155;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000006985.3|UniProtKB=F6SBF1 F6SBF1 PTHR11246:SF5 PRE-MRNA SPLICING FACTOR PRE-MRNA-SPLICING FACTOR SYF1 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;RNA processing#GO:0006396;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;protein-RNA complex assembly#GO:0022618;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;mRNA splicing, via spliceosome#GO:0000398;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;protein-containing complex organization#GO:0043933;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;ribonucleoprotein complex biogenesis#GO:0022613;mRNA processing#GO:0006397;protein-RNA complex organization#GO:0071826;RNA splicing, via transesterification reactions#GO:0000375 catalytic step 2 spliceosome#GO:0071013;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;U2-type spliceosomal complex#GO:0005684;cellular anatomical entity#GO:0110165;organelle#GO:0043226;post-mRNA release spliceosomal complex#GO:0071014;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;Prp19 complex#GO:0000974;nuclear protein-containing complex#GO:0140513 RNA splicing factor#PC00148;RNA processing factor#PC00147 CIOIN|Ensembl=ENSCING00000000496.3|UniProtKB=F6VQE7 F6VQE7 PTHR12101:SF17 POPEYE DOMAIN CONTAINING PROTEIN BLOOD VESSEL EPICARDIAL SUBSTANCE nucleotide binding#GO:0000166;carbohydrate derivative binding#GO:0097367;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;anion binding#GO:0043168 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;sarcolemma#GO:0042383 CIOIN|Ensembl=ENSCING00000002935.3|UniProtKB=F6U0U0 F6U0U0 PTHR10259:SF11 THIOPURINE S-METHYLTRANSFERASE THIOPURINE S-METHYLTRANSFERASE methyltransferase activity#GO:0008168;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757 methyltransferase#PC00155 CIOIN|Ensembl=ENSCING00000002005.3|UniProtKB=F6WT90 F6WT90 PTHR33767:SF3 LEUCINE RICH ADAPTOR PROTEIN 1-LIKE LEUCINE RICH ADAPTOR PROTEIN 1-LIKE regulation of response to stimulus#GO:0048583;biological regulation#GO:0065007;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;regulation of signaling#GO:0023051 CIOIN|Ensembl=ENSCING00000005632.3|UniProtKB=F7A8S2 F7A8S2 LOC100183227 PTHR14927:SF0 NUCLEOLAR PROTEIN 10 NUCLEOLAR PROTEIN 10 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;maturation of SSU-rRNA#GO:0030490;ribosomal small subunit biogenesis#GO:0042274;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;small-subunit processome#GO:0032040;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;nuclear lumen#GO:0031981;90S preribosome#GO:0030686 CIOIN|Ensembl=ENSCING00000012947.2|UniProtKB=F6RGM5 F6RGM5 PTHR23220:SF133 INTEGRIN ALPHA INTEGRIN ALPHA-PS2 cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;integrin binding#GO:0005178;binding#GO:0005488;signaling receptor binding#GO:0005102 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cell adhesion mediated by integrin#GO:0033627;cell-cell adhesion#GO:0098609;cell communication#GO:0007154;cell adhesion#GO:0007155;cell-substrate adhesion#GO:0031589;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cell-matrix adhesion#GO:0007160;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;integrin-mediated signaling pathway#GO:0007229;biological regulation#GO:0065007;signaling#GO:0023052 receptor complex#GO:0043235;membrane protein complex#GO:0098796;external side of plasma membrane#GO:0009897;cell surface#GO:0009986;protein-containing complex#GO:0032991;plasma membrane signaling receptor complex#GO:0098802;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 cell adhesion molecule#PC00069;integrin#PC00126 Integrin signalling pathway#P00034>Integrin alpha#P00941 CIOIN|Ensembl=ENSCING00000003240.2|UniProtKB=F6ZNT5 F6ZNT5 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE SSU-1 sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824 cellular metabolic process#GO:0044237;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000023573.1|UniProtKB=H2XZ57 H2XZ57 PTHR32510:SF3 TRANSMEMBRANE PROTEIN 98 TRANSMEMBRANE PROTEIN 98 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000009149.3|UniProtKB=F7BBD1 F7BBD1 PTHR13162:SF8 CCR4-NOT TRANSCRIPTION COMPLEX CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 1 negative regulation of gene expression#GO:0010629;regulation of catabolic process#GO:0009894;heterocycle catabolic process#GO:0046700;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;nucleobase-containing compound metabolic process#GO:0006139;RNA destabilization#GO:0050779;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;regulation of RNA stability#GO:0043487;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;positive regulation of mRNA catabolic process#GO:0061014;regulation of cellular process#GO:0050794;post-transcriptional regulation of gene expression#GO:0010608;positive regulation of catabolic process#GO:0009896;mRNA destabilization#GO:0061157;nucleobase-containing compound catabolic process#GO:0034655;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;regulation of mRNA stability#GO:0043488;RNA metabolic process#GO:0016070;positive regulation of cellular catabolic process#GO:0031331;cellular nitrogen compound catabolic process#GO:0044270;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;mRNA catabolic process#GO:0006402;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;regulation of gene expression#GO:0010468;organic substance catabolic process#GO:1901575;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;positive regulation of mRNA metabolic process#GO:1903313;heterocycle metabolic process#GO:0046483;negative regulation of biosynthetic process#GO:0009890;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;positive regulation of RNA metabolic process#GO:0051254 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;protein-containing complex#GO:0032991;P-body#GO:0000932;CCR4-NOT complex#GO:0030014;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464;intracellular anatomical structure#GO:0005622 mRNA polyadenylation factor#PC00146 CIOIN|Ensembl=ENSCING00000001389.3|UniProtKB=F6ZTV7 F6ZTV7 PTHR22736:SF2 COILED-COIL DOMAIN-CONTAINING PROTEIN 66 COILED-COIL DOMAIN-CONTAINING PROTEIN 66 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cell projection organization#GO:0030030;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031 supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;cell projection#GO:0042995;cilium#GO:0005929;microtubule#GO:0005874 CIOIN|Ensembl=ENSCING00000013573.2|UniProtKB=F6YBB2 F6YBB2 PTHR46680:SF3 NF-KAPPA-B INHIBITOR ALPHA NF-KAPPA-B INHIBITOR CACTUS Toll pathway-drosophila#P06217>CACT#P06342 CIOIN|Ensembl=ENSCING00000016712.2|UniProtKB=F6RTI9 F6RTI9 PTHR23503:SF132 SOLUTE CARRIER FAMILY 2 SOLUTE CARRIER FAMILY 2, FACILITATED GLUCOSE TRANSPORTER MEMBER 5-LIKE transmembrane transporter activity#GO:0022857;sugar transmembrane transporter activity#GO:0051119;transporter activity#GO:0005215;carbohydrate transmembrane transporter activity#GO:0015144 localization#GO:0051179;organic substance transport#GO:0071702;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;organic anion transport#GO:0015711;transport#GO:0006810;vitamin transport#GO:0051180;glucose transmembrane transport#GO:1904659;cellular process#GO:0009987;carbohydrate transmembrane transport#GO:0034219;carbohydrate transport#GO:0008643 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000003965.3|UniProtKB=F6Z2W9 F6Z2W9 LOC100182682 PTHR48228:SF5 SUCCINYL-COA--D-CITRAMALATE COA-TRANSFERASE ALPHA-METHYLACYL-COA RACEMASE transferase#PC00220;metabolite interconversion enzyme#PC00262 Coenzyme A linked carnitine metabolism#P02732>L-carnitine dehydratase#P02864;Carnitine metabolism#P02733>Carnitine dehydratase#P02866 CIOIN|Ensembl=ENSCING00000008630.3|UniProtKB=F7AHP3 F7AHP3 PTHR46276:SF1 E3 UBIQUITIN-PROTEIN LIGASE UBR5 E3 UBIQUITIN-PROTEIN LIGASE UBR5 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 regulation of cell communication#GO:0010646;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;positive regulation of Wnt signaling pathway#GO:0030177;post-translational protein modification#GO:0043687;regulation of canonical Wnt signaling pathway#GO:0060828;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of canonical Wnt signaling pathway#GO:0090263;positive regulation of response to stimulus#GO:0048584;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;regulation of Wnt signaling pathway#GO:0030111;regulation of signal transduction#GO:0009966;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;protein polyubiquitination#GO:0000209;positive regulation of signaling#GO:0023056;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;positive regulation of biological process#GO:0048518;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 Hedgehog signaling pathway#P00025>Ubiquitin ligase#P00693 CIOIN|Ensembl=ENSCING00000020162.1|UniProtKB=H2XVA3 H2XVA3 PTHR10807:SF73 MYOTUBULARIN-RELATED LD06050P hydrolase activity, acting on ester bonds#GO:0016788;phosphatase binding#GO:0019902;phosphatase activity#GO:0016791;binding#GO:0005488;catalytic activity#GO:0003824;phosphatidylinositol-3,5-bisphosphate phosphatase activity#GO:0106018;hydrolase activity#GO:0016787;enzyme binding#GO:0019899;protein binding#GO:0005515;protein phosphatase binding#GO:0019903;phosphoric ester hydrolase activity#GO:0042578 lipid metabolic process#GO:0006629;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of catabolic process#GO:0009894;lipid modification#GO:0030258;phospholipid metabolic process#GO:0006644;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;glycerolipid metabolic process#GO:0046486;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;phospholipid dephosphorylation#GO:0046839;phosphatidylinositol dephosphorylation#GO:0046856;regulation of autophagy#GO:0010506;negative regulation of cellular catabolic process#GO:0031330;cellular metabolic process#GO:0044237;glycerophospholipid metabolic process#GO:0006650;phosphatidylinositol metabolic process#GO:0046488;negative regulation of metabolic process#GO:0009892;regulation of cellular catabolic process#GO:0031329;negative regulation of autophagy#GO:0010507;cellular process#GO:0009987;primary metabolic process#GO:0044238;negative regulation of catabolic process#GO:0009895;regulation of cellular process#GO:0050794;dephosphorylation#GO:0016311;biological regulation#GO:0065007;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;phosphatase#PC00181 CIOIN|Ensembl=ENSCING00000018458.1|UniProtKB=H2XTE0 H2XTE0 LOC100180027 PTHR22146:SF8 CAT EYE SYNDROME CRITICAL REGION PROTEIN 6 PROTEIN FAM166B CIOIN|Ensembl=ENSCING00000023711.1|UniProtKB=H2XTE2 H2XTE2 PTHR16146:SF46 INTELECTIN INTELECTIN-1A-RELATED CIOIN|Ensembl=ENSCING00000009080.3|UniProtKB=F6QEK5 F6QEK5 LOC100186815 PTHR11551:SF13 INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN INSULIN-LIKE GROWTH FACTOR-BINDING PROTEIN 2 protease inhibitor#PC00191;protein-binding activity modulator#PC00095 CIOIN|Ensembl=ENSCING00000003481.3|UniProtKB=H2XY63 H2XY63 PTHR11929:SF145 ALPHA- 1,3 -FUCOSYLTRANSFERASE ALPHA-(1,3)-FUCOSYLTRANSFERASE FUT-1 transferase activity#GO:0016740;fucosyltransferase activity#GO:0008417;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 glycosylation#GO:0070085;metabolic process#GO:0008152 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000009554.3|UniProtKB=F6U8F3 F6U8F3 LOC100180168 PTHR13586:SF0 SCD6 PROTEIN-RELATED TRAILER HITCH, ISOFORM H nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular component organization#GO:0016043;non-membrane-bounded organelle assembly#GO:0140694;P-body assembly#GO:0033962;cellular process#GO:0009987 supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;P-body#GO:0000932;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic ribonucleoprotein granule#GO:0036464 RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000009872.3|UniProtKB=A0A1W5B8X3 A0A1W5B8X3 LOC100180004 PTHR23423:SF21 ORGANIC SOLUTE TRANSPORTER-RELATED ORGANIC SOLUTE TRANSPORTER SUBUNIT ALPHA-LIKE localization#GO:0051179;establishment of localization#GO:0051234;transport#GO:0006810 cellular anatomical entity#GO:0110165;membrane#GO:0016020 transporter#PC00227 CIOIN|Ensembl=ENSCING00000019880.1|UniProtKB=H2XPV1 H2XPV1 PTHR19134:SF562 RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE PROTEIN-TYROSINE-PHOSPHATASE hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;protein tyrosine phosphatase activity#GO:0004725;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 protein phosphatase#PC00195;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000006765.3|UniProtKB=H2XNG3 H2XNG3 zf(c2h2)-30 PTHR24406:SF36 TRANSCRIPTIONAL REPRESSOR CTCFL-RELATED TRANSCRIPTIONAL REPRESSOR CTCFL nucleic acid binding#GO:0003676;protein-containing complex binding#GO:0044877;chromatin DNA binding#GO:0031490;binding#GO:0005488;organic cyclic compound binding#GO:0097159;chromatin binding#GO:0003682;DNA binding#GO:0003677 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;chromosome#GO:0005694;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 CIOIN|Ensembl=ENSCING00000019644.1|UniProtKB=H2Y3E5 H2Y3E5 PTHR43775:SF7 FATTY ACID SYNTHASE FATTY ACID SYNTHASE transferase activity#GO:0016740;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity#GO:0003824 organic acid biosynthetic process#GO:0016053;lipid metabolic process#GO:0006629;oxoacid metabolic process#GO:0043436;monocarboxylic acid biosynthetic process#GO:0072330;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;fatty acid metabolic process#GO:0006631;small molecule biosynthetic process#GO:0044283;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;fatty acid biosynthetic process#GO:0006633;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 CIOIN|Ensembl=ENSCING00000004663.3|UniProtKB=F6PTW3 F6PTW3 PTHR43115:SF4 DEHYDROGENASE/REDUCTASE SDR FAMILY MEMBER 11 DEHYDROGENASE_REDUCTASE SDR FAMILY MEMBER 11 oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000012480.2|UniProtKB=F6U621 F6U621 LOC100177190 PTHR23248:SF63 PHOSPHOLIPID SCRAMBLASE-RELATED PHOSPHOLIPID SCRAMBLASE phospholipid transporter activity#GO:0005548;transporter activity#GO:0005215;lipid transporter activity#GO:0005319 organophosphate ester transport#GO:0015748;macromolecule localization#GO:0033036;membrane organization#GO:0061024;plasma membrane organization#GO:0007009;transport#GO:0006810;plasma membrane phospholipid scrambling#GO:0017121;endomembrane system organization#GO:0010256;cellular component organization#GO:0016043;regulation of membrane lipid distribution#GO:0097035;phospholipid transport#GO:0015914;cellular process#GO:0009987;lipid transport#GO:0006869;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;biological regulation#GO:0065007;lipid translocation#GO:0034204;lipid localization#GO:0010876;phospholipid translocation#GO:0045332 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transporter#PC00227 CIOIN|Ensembl=ENSCING00000004535.3|UniProtKB=F7A8L8 F7A8L8 PTHR13037:SF24 FORMIN POLYCOMB PROTEIN PCL-RELATED CIOIN|Ensembl=ENSCING00000008988.3|UniProtKB=F6PKL5 F6PKL5 LOC100186653 PTHR43888:SF10 DNAJ-LIKE-2, ISOFORM A-RELATED DNAJ-LIKE-2, ISOFORM A protein binding#GO:0005515;protein-folding chaperone binding#GO:0051087;binding#GO:0005488 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein folding#GO:0006457;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 chaperone#PC00072 CIOIN|Ensembl=ENSCING00000023138.1|UniProtKB=H2XUY3 H2XUY3 PTHR11732:SF506 ALDO/KETO REDUCTASE ALDO-KETO REDUCTASE 1B, ISOFORM C-RELATED oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 reductase#PC00198;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000006114.1|UniProtKB=F6WDU3 F6WDU3 PTHR24039:SF58 FIBRILLIN-RELATED EGF-LIKE DOMAIN-CONTAINING PROTEIN extracellular matrix structural protein#PC00103 CIOIN|Ensembl=ENSCING00000001863.3|UniProtKB=F6T6E4 F6T6E4 LOC100183609 PTHR12363:SF33 TRANSPORTIN 3 AND IMPORTIN 13 IMPORTIN-13 cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;protein localization to nucleus#GO:0034504;nitrogen compound transport#GO:0071705;establishment of protein localization to organelle#GO:0072594;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;protein import into nucleus#GO:0006606;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;protein localization to organelle#GO:0033365;nuclear transport#GO:0051169;import into nucleus#GO:0051170 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 transporter#PC00227 CIOIN|Ensembl=ENSCING00000008920.3|UniProtKB=F6QAP0 F6QAP0 ci-zf(ring)-3 PTHR46170:SF1 GATOR COMPLEX PROTEIN WDR59 GATOR COMPLEX PROTEIN WDR59 molecular adaptor activity#GO:0060090;signaling adaptor activity#GO:0035591;protein-macromolecule adaptor activity#GO:0030674 positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;response to extracellular stimulus#GO:0009991;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;cellular response to starvation#GO:0009267;positive regulation of TOR signaling#GO:0032008;regulation of signal transduction#GO:0009966;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;cellular response to extracellular stimulus#GO:0031668;regulation of cell communication#GO:0010646;positive regulation of TORC1 signaling#GO:1904263;cellular response to stimulus#GO:0051716;regulation of TORC1 signaling#GO:1903432;cell communication#GO:0007154;response to nutrient levels#GO:0031667;cellular process#GO:0009987;regulation of TOR signaling#GO:0032006;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;response to stress#GO:0006950;cellular response to nutrient levels#GO:0031669;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;response to starvation#GO:0042594;biological regulation#GO:0065007;cellular response to external stimulus#GO:0071496;cellular response to amino acid starvation#GO:0034198;cellular response to stress#GO:0033554 bounding membrane of organelle#GO:0098588;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;Seh1-associated complex#GO:0035859;intracellular membrane-bounded organelle#GO:0043231;vacuolar membrane#GO:0005774;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Gene_ORFName=Cin.36927|UniProtKB=F6RCC2 F6RCC2 Cin.36927 PTHR12592:SF0 ATP-DEPENDENT (S)-NAD(P)H-HYDRATE DEHYDRATASE FAMILY MEMBER ATP-DEPENDENT (S)-NAD(P)H-HYDRATE DEHYDRATASE cellular metabolic process#GO:0044237;cellular process#GO:0009987;metabolic process#GO:0008152 dehydratase#PC00091;lyase#PC00144 CIOIN|Ensembl=ENSCING00000001247.3|UniProtKB=F7AEB2 F7AEB2 LOC100180230 PTHR11475:SF4 OXIDASE/PEROXIDASE CHORION PEROXIDASE oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;antioxidant activity#GO:0016209;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 peroxidase#PC00180;metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000008535.3|UniProtKB=A0A1W3JM58 A0A1W3JM58 LOC100179230 PTHR45794:SF1 LEUCYL-TRNA SYNTHETASE LEUCINE--TRNA LIGASE, CYTOPLASMIC catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;ligase activity#GO:0016874;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;peptide biosynthetic process#GO:0043043;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 aminoacyl-tRNA synthetase#PC00047;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000001267.3|UniProtKB=F6ZVC8 F6ZVC8 LOC100182393 PTHR23264:SF35 NUCLEOTIDE-BINDING PROTEIN NBP35 YEAST -RELATED CYTOSOLIC FE-S CLUSTER ASSEMBLY FACTOR NUBP1 small molecule binding#GO:0036094;binding#GO:0005488;iron-sulfur cluster binding#GO:0051536 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;iron-sulfur cluster assembly#GO:0016226;cellular component organization#GO:0016043;cellular process#GO:0009987 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000002083.3|UniProtKB=F7BLL7 F7BLL7 PTHR23421:SF199 BETA-GALACTOSIDASE RELATED BETA-GALACTOSIDASE hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 galactosidase#PC00104;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000011969.2|UniProtKB=F6SKB5 F6SKB5 PTHR24373:SF387 SLIT RELATED LEUCINE-RICH REPEAT NEURONAL PROTEIN LEUCINE-RICH REPEATS AND IMMUNOGLOBULIN-LIKE DOMAINS PROTEIN SMA-10 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 transmembrane signal receptor#PC00197 CIOIN|Ensembl=ENSCING00000009955.3|UniProtKB=F6R579 F6R579 LOC100186509 PTHR12478:SF16 DNA-DAMAGE-INDUCIBLE TRANSCRIPT 4 PROTEIN DDIT4 PROTEIN CHARYBDE-RELATED regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;apoptotic process#GO:0006915;regulation of signaling#GO:0023051;biological regulation#GO:0065007;cell death#GO:0008219;programmed cell death#GO:0012501;cellular process#GO:0009987;regulation of intracellular signal transduction#GO:1902531;regulation of TOR signaling#GO:0032006 CIOIN|Ensembl=ENSCING00000011306.2|UniProtKB=F6ZE98 F6ZE98 PTHR46205:SF3 LOQUACIOUS, ISOFORM B LOQUACIOUS, ISOFORM B CIOIN|Ensembl=ENSCING00000016452.2|UniProtKB=F6Z6T5 F6Z6T5 PTHR12369:SF11 CHONDROITIN SYNTHASE HEXOSYLTRANSFERASE transferase activity#GO:0016740;catalytic activity#GO:0003824;glycosyltransferase activity#GO:0016757;hexosyltransferase activity#GO:0016758;UDP-glycosyltransferase activity#GO:0008194 glycosyltransferase#PC00111 CIOIN|Ensembl=ENSCING00000025022.1|UniProtKB=H2XJX2 H2XJX2 PTHR11984:SF53 CONNEXIN GAP JUNCTION PROTEIN wide pore channel activity#GO:0022829;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;channel activity#GO:0015267 biological regulation#GO:0065007;regulation of biological process#GO:0050789;cell communication#GO:0007154;cellular process#GO:0009987;cell-cell signaling#GO:0007267;signaling#GO:0023052 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 cell junction protein#PC00070;gap junction#PC00105 CIOIN|Ensembl=ENSCING00000002223.3|UniProtKB=F6Z750 F6Z750 LOC100180956 PTHR21676:SF6 PROTEIN STUM PROTEIN STUM CIOIN|Ensembl=ENSCING00000009746.3|UniProtKB=F7ACE2 F7ACE2 PTHR11388:SF160 ORGANIC ANION TRANSPORTER SOLUTE CARRIER ORGANIC ANION TRANSPORTER FAMILY MEMBER secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 localization#GO:0051179;organic substance transport#GO:0071702;establishment of localization#GO:0051234;organic anion transport#GO:0015711;transport#GO:0006810 basal plasma membrane#GO:0009925;basolateral plasma membrane#GO:0016323;plasma membrane region#GO:0098590;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;basal part of cell#GO:0045178;plasma membrane#GO:0005886 transporter#PC00227 CIOIN|Ensembl=ENSCING00000023040.1|UniProtKB=F6XCJ9 F6XCJ9 LOC100180869 PTHR11119:SF3 XANTHINE-URACIL / VITAMIN C PERMEASE FAMILY MEMBER LD30822P transporter#PC00227 CIOIN|Ensembl=ENSCING00000008658.3|UniProtKB=F6ZF70 F6ZF70 PTHR11822:SF21 NADP-SPECIFIC ISOCITRATE DEHYDROGENASE ISOCITRATE DEHYDROGENASE [NADP], MITOCHONDRIAL dehydrogenase#PC00092;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000021152.1|UniProtKB=H2XSF3 H2XSF3 PTHR13715:SF79 RYANODINE RECEPTOR AND IP3 RECEPTOR RYANODINE RECEPTOR ligand-gated ion channel#PC00141;ion channel#PC00133;transporter#PC00227 Beta1 adrenergic receptor signaling pathway#P04377>ER-type Ca2+ channel#P04434;Metabotropic glutamate receptor group I pathway#P00041>IP3R#P01056;Beta2 adrenergic receptor signaling pathway#P04378>ER-type Ca2+ channel#P04441 CIOIN|Ensembl=ENSCING00000009534.3|UniProtKB=F6UXC1 F6UXC1 LOC100187231 PTHR19368:SF15 XLR/SCP3/FAM9 XLR_SYCP3_FAM9 DOMAIN-CONTAINING PROTEIN germ cell development#GO:0007281;male gamete generation#GO:0048232;cellular developmental process#GO:0048869;gamete generation#GO:0007276;cellular process involved in reproduction in multicellular organism#GO:0022412;multicellular organism reproduction#GO:0032504;meiotic cell cycle#GO:0051321;developmental process#GO:0032502;spermatid differentiation#GO:0048515;cellular process#GO:0009987;cell development#GO:0048468;developmental process involved in reproduction#GO:0003006;cell differentiation#GO:0030154;spermatid development#GO:0007286;reproduction#GO:0000003;anatomical structure development#GO:0048856;spermatogenesis#GO:0007283;sexual reproduction#GO:0019953;reproductive process#GO:0022414;cell cycle#GO:0007049;multicellular organismal process#GO:0032501;multicellular organismal reproductive process#GO:0048609 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;condensed chromosome#GO:0000793;intracellular organelle lumen#GO:0070013;condensed nuclear chromosome#GO:0000794;synaptonemal structure#GO:0099086;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;synaptonemal complex#GO:0000795 CIOIN|Ensembl=ENSCING00000006056.3|UniProtKB=F6ZZD5 F6ZZD5 LOC100175053 PTHR22959:SF0 PYM PROTEIN PARTNER OF Y14 AND MAGO nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;cellular component disassembly#GO:0022411;protein-containing complex disassembly#GO:0032984;cellular process#GO:0009987;protein-containing complex organization#GO:0043933 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000016827.2|UniProtKB=A0A1W2WAC8 A0A1W2WAC8 LOC100184669 PTHR47633:SF16 IMMUNOGLOBULIN CAVP-TARGET PROTEIN-LIKE transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;kinase activity#GO:0016301;protein kinase activity#GO:0004672 CIOIN|Ensembl=ENSCING00000024539.1|UniProtKB=H2XWR6 H2XWR6 LOC108950774 PTHR14226:SF79 NEUROPATHY TARGET ESTERASE/SWISS CHEESE D.MELANOGASTER CYCLIC NUCLEOTIDE-BINDING DOMAIN-CONTAINING PROTEIN hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;phospholipase activity#GO:0004620;catalytic activity#GO:0003824;lysophospholipase activity#GO:0004622 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 esterase#PC00097;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000003855.3|UniProtKB=A0A1W2WIY7 A0A1W2WIY7 LOC100183458 PTHR24068:SF503 UBIQUITIN-CONJUGATING ENZYME E2 UBC CORE DOMAIN-CONTAINING PROTEIN ubiquitin-like protein conjugating enzyme activity#GO:0061650;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;ubiquitin-like protein ligase binding#GO:0044389;enzyme binding#GO:0019899;ubiquitin conjugating enzyme activity#GO:0061631;protein binding#GO:0005515;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin protein ligase binding#GO:0031625 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;protein polyubiquitination#GO:0000209;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000000092.3|UniProtKB=F6T5Z7 F6T5Z7 LOC100179756 PTHR23320:SF165 MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MS4A -RELATED MARVEL DOMAIN-CONTAINING PROTEIN transporter#PC00227 CIOIN|Ensembl=ENSCING00000008720.3|UniProtKB=F6WBW5 F6WBW5 PTHR23064:SF72 TROPONIN TROPONIN C, SKELETAL MUSCLE cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 CIOIN|Ensembl=ENSCING00000013611.2|UniProtKB=F6V1S5 F6V1S5 inx PTHR15759:SF6 PANNEXIN INNEXIN CIOIN|Ensembl=ENSCING00000013219.2|UniProtKB=F6V597 F6V597 PTHR19297:SF191 GLYCOSYLTRANSFERASE 14 FAMILY MEMBER PROTEIN XYLOSYLTRANSFERASE acetylglucosaminyltransferase activity#GO:0008375;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194;hexosyltransferase activity#GO:0016758 glycosyltransferase#PC00111;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000009117.3|UniProtKB=F6SPZ6 F6SPZ6 PTHR12346:SF0 SIN3B-RELATED SIN3A, ISOFORM G molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714;protein-macromolecule adaptor activity#GO:0030674 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of biosynthetic process#GO:0009890;negative regulation of RNA metabolic process#GO:0051253;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;histone deacetylase complex#GO:0000118;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 chromatin/chromatin-binding, or -regulatory protein#PC00077 Huntington disease#P00029>Sin3A#P00771 CIOIN|Ensembl=ENSCING00000016739.2|UniProtKB=F6QZU2 F6QZU2 LOC100179636 PTHR22776:SF89 MARVEL-CONTAINING POTENTIAL LIPID RAFT-ASSOCIATED PROTEIN CKLF-LIKE MARVEL TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN 7 cellular anatomical entity#GO:0110165;membrane#GO:0016020 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000006439.3|UniProtKB=F6QL57 F6QL57 LOC100180897 PTHR24096:SF149 LONG-CHAIN-FATTY-ACID--COA LIGASE AMP-BINDING DOMAIN-CONTAINING PROTEIN-RELATED ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877 metabolite interconversion enzyme#PC00262;ligase#PC00142 CIOIN|Gene_ORFName=COS41.2|UniProtKB=P91580 P91580 COS41.2 PTHR47978:SF40 FAMILY NOT NAMED RAS-RELATED PROTEIN RAB-33 GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;ion binding#GO:0043167;anion binding#GO:0043168 cytoplasm#GO:0005737;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 small GTPase#PC00208;G-protein#PC00020 CIOIN|Ensembl=ENSCING00000012441.2|UniProtKB=F6UV18 F6UV18 LOC100186959 PTHR11588:SF278 TUBULIN TUBULIN ALPHA CHAIN-LIKE 3 carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;structural molecule activity#GO:0005198;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167;structural constituent of cytoskeleton#GO:0005200 cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;microtubule-based process#GO:0007017;organelle organization#GO:0006996;microtubule cytoskeleton organization#GO:0000226;cytoskeleton organization#GO:0007010;cell cycle#GO:0007049;cellular component organization#GO:0016043;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622 tubulin#PC00228;microtubule or microtubule-binding cytoskeletal protein#PC00157 CIOIN|Ensembl=ENSCING00000006943.3|UniProtKB=F6VNH0 F6VNH0 LOC100175623 PTHR11431:SF75 FERRITIN FERRITIN cation binding#GO:0043169;ferrous iron binding#GO:0008198;small molecule binding#GO:0036094;binding#GO:0005488;iron ion binding#GO:0005506;transition metal ion binding#GO:0046914;metal ion binding#GO:0046872;ion binding#GO:0043167 localization#GO:0051179;inorganic ion homeostasis#GO:0098771;cellular localization#GO:0051641;intracellular iron ion homeostasis#GO:0006879;maintenance of location#GO:0051235;maintenance of location in cell#GO:0051651;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;homeostatic process#GO:0042592;intracellular monoatomic ion homeostasis#GO:0006873;chemical homeostasis#GO:0048878;cellular process#GO:0009987;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;monoatomic ion homeostasis#GO:0050801 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 storage protein#PC00210 CIOIN|Ensembl=ENSCING00000025179.1|UniProtKB=H2XVY8 H2XVY8 PTHR45712:SF27 AGAP008170-PA LRRNT DOMAIN-CONTAINING PROTEIN extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 CIOIN|Ensembl=ENSCING00000006906.3|UniProtKB=F6WAZ5 F6WAZ5 PTHR45625:SF4 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-RELATED PEPTIDYLPROLYL ISOMERASE DOMAIN AND WD REPEAT-CONTAINING PROTEIN 1 peptidyl-prolyl cis-trans isomerase activity#GO:0003755;isomerase activity#GO:0016853;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;protein peptidyl-prolyl isomerization#GO:0000413;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 chaperone#PC00072 CIOIN|Ensembl=ENSCING00000003821.3|UniProtKB=F6WMR0 F6WMR0 PTHR11863:SF226 STEROL DESATURASE FATTY ACID HYDROXYLASE DOMAIN-CONTAINING PROTEIN 2-RELATED oxidase#PC00175;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000014152.2|UniProtKB=F7ARA7 F7ARA7 PTHR10845:SF259 REGULATOR OF G PROTEIN SIGNALING RGS DOMAIN-CONTAINING PROTEIN-RELATED G-protein modulator#PC00022;protein-binding activity modulator#PC00095;GTPase-activating protein#PC00257 CIOIN|Ensembl=ENSCING00000000334.3|UniProtKB=F6WEK5 F6WEK5 LOC100177589 PTHR12369:SF45 CHONDROITIN SYNTHASE HEXOSYLTRANSFERASE transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;UDP-glycosyltransferase activity#GO:0008194 glycoprotein biosynthetic process#GO:0009101;glycosaminoglycan metabolic process#GO:0030203;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;chondroitin sulfate proteoglycan biosynthetic process#GO:0050650;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;proteoglycan metabolic process#GO:0006029;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;proteoglycan biosynthetic process#GO:0030166;nitrogen compound metabolic process#GO:0006807;aminoglycan biosynthetic process#GO:0006023;glycosaminoglycan biosynthetic process#GO:0006024;aminoglycan metabolic process#GO:0006022;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 glycosyltransferase#PC00111 CIOIN|Ensembl=ENSCING00000005414.3|UniProtKB=F6Z998 F6Z998 PTHR10732:SF0 40S RIBOSOMAL PROTEIN S17 40S RIBOSOMAL PROTEIN S17 ribosomal protein#PC00202;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000019322.1|UniProtKB=H2Y1S2 H2Y1S2 PTHR11829:SF206 FORKHEAD BOX PROTEIN FORKHEAD BOX PROTEIN Q1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;anatomical structure morphogenesis#GO:0009653;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 CIOIN|Ensembl=ENSCING00000021133.1|UniProtKB=H2XWF2 H2XWF2 PTHR11085:SF10 NAD-DEPENDENT PROTEIN DEACYLASE SIRTUIN-5, MITOCHONDRIAL-RELATED NAD-DEPENDENT PROTEIN DEACYLASE SIRTUIN-5, MITOCHONDRIAL-RELATED nucleotide binding#GO:0000166;histone modifying activity#GO:0140993;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;deacetylase activity#GO:0019213;histone deacetylase activity#GO:0004407;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;anion binding#GO:0043168;catalytic activity, acting on a protein#GO:0140096 CIOIN|Ensembl=ENSCING00000019994.1|UniProtKB=H2Y1U8 H2Y1U8 PTHR47977:SF33 RAS-RELATED PROTEIN RAB RAS-RELATED PROTEIN RAB-27B GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;anion binding#GO:0043168;ion binding#GO:0043167 positive regulation of secretion#GO:0051047;transport#GO:0006810;positive regulation of transport#GO:0051050;regulation of secretion by cell#GO:1903530;vesicle-mediated transport#GO:0016192;regulation of localization#GO:0032879;cellular process#GO:0009987;regulation of vesicle-mediated transport#GO:0060627;positive regulation of cellular process#GO:0048522;localization#GO:0051179;regulation of biological process#GO:0050789;regulation of transport#GO:0051049;exocytosis#GO:0006887;establishment of localization#GO:0051234;regulation of cellular process#GO:0050794;regulation of secretion#GO:0051046;secretion#GO:0046903;biological regulation#GO:0065007;positive regulation of secretion by cell#GO:1903532;positive regulation of biological process#GO:0048518;export from cell#GO:0140352;regulation of exocytosis#GO:0017157;secretion by cell#GO:0032940 intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;secretory granule#GO:0030141;Golgi apparatus#GO:0005794;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;apical part of cell#GO:0045177;intracellular anatomical structure#GO:0005622;apical plasma membrane#GO:0016324;cytoplasm#GO:0005737;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;plasma membrane region#GO:0098590;membrane-bounded organelle#GO:0043227;transport vesicle#GO:0030133;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 small GTPase#PC00208;G-protein#PC00020 CIOIN|Ensembl=ENSCING00000020583.1|UniProtKB=H2Y1T7 H2Y1T7 LOC100176239 PTHR11785:SF528 AMINO ACID TRANSPORTER AMINO ACID TRANSPORTER PROTEIN JHI-21 L-amino acid transmembrane transporter activity#GO:0015179;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;amino acid transmembrane transporter activity#GO:0015171;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215;organic acid transmembrane transporter activity#GO:0005342 localization#GO:0051179;organic substance transport#GO:0071702;amino acid transmembrane transport#GO:0003333;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;amino acid transport#GO:0006865;organic anion transport#GO:0015711;organic acid transport#GO:0015849;transport#GO:0006810;nitrogen compound transport#GO:0071705;organic acid transmembrane transport#GO:1903825;carboxylic acid transport#GO:0046942;cellular process#GO:0009987;carboxylic acid transmembrane transport#GO:1905039 transporter#PC00227 CIOIN|Ensembl=ENSCING00000024328.1|UniProtKB=H2XRH2 H2XRH2 PTHR16121:SF0 CAP-SPECIFIC MRNA (NUCLEOSIDE-2'-O-)-METHYLTRANSFERASE 1-RELATED CAP-SPECIFIC MRNA (NUCLEOSIDE-2'-O-)-METHYLTRANSFERASE 1 catalytic activity, acting on RNA#GO:0140098;transferase activity#GO:0016740;O-methyltransferase activity#GO:0008171;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;RNA methyltransferase activity#GO:0008173 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA modification#GO:0009451;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;mRNA modification#GO:0016556;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;macromolecule methylation#GO:0043414;methylation#GO:0032259;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;mRNA processing#GO:0006397;RNA methylation#GO:0001510;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000008400.3|UniProtKB=F6XS58 F6XS58 LOC100177480 PTHR14647:SF87 GALACTOSE-3-O-SULFOTRANSFERASE PUTATIVE-RELATED transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000007564.3|UniProtKB=F7AUU8 F7AUU8 PTHR17490:SF10 SUA5 THREONYLCARBAMOYL-AMP SYNTHASE tRNA binding#GO:0000049;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;transferase activity#GO:0016740;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;nucleotidyltransferase activity#GO:0016779;transferase activity, transferring phosphorus-containing groups#GO:0016772 biological regulation#GO:0065007;regulation of biological quality#GO:0065008 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000005010.3|UniProtKB=F6TXZ0 F6TXZ0 PTHR24123:SF141 ANKYRIN REPEAT-CONTAINING ANKYRIN 2, ISOFORM U scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000007163.3|UniProtKB=F6ZB89 F6ZB89 eph3 PTHR24416:SF539 TYROSINE-PROTEIN KINASE RECEPTOR RECEPTOR PROTEIN-TYROSINE KINASE signaling receptor activity#GO:0038023;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;molecular transducer activity#GO:0060089;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672;transmembrane signaling receptor activity#GO:0004888 signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;positive regulation of cellular metabolic process#GO:0031325;developmental process#GO:0032502;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;regulation of molecular function#GO:0065009;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;positive regulation of phosphorylation#GO:0042327;cellular response to stimulus#GO:0051716;positive regulation of catalytic activity#GO:0043085;multicellular organism development#GO:0007275;positive regulation of phosphorus metabolic process#GO:0010562;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphate metabolic process#GO:0045937;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;multicellular organismal process#GO:0032501;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 receptor complex#GO:0043235;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 CIOIN|Ensembl=ENSCING00000009739.3|UniProtKB=F6TIH6 F6TIH6 LOC100178347 PTHR23112:SF43 G PROTEIN-COUPLED RECEPTOR 157-RELATED CYCLIC AMP RECEPTOR-LIKE PROTEIN A signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 CIOIN|Ensembl=ENSCING00000018013.1|UniProtKB=H2Y359 H2Y359 PTHR45750:SF3 GH11602P HISTONE ACETYLTRANSFERASE histone modifying activity#GO:0140993;histone acetyltransferase activity#GO:0004402;transferase activity#GO:0016740;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;N-acetyltransferase activity#GO:0008080;acetyltransferase activity#GO:0016407;peptide-lysine-N-acetyltransferase activity#GO:0061733;peptide N-acetyltransferase activity#GO:0034212;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;N-acyltransferase activity#GO:0016410 positive regulation of nitrogen compound metabolic process#GO:0051173;protein-DNA complex organization#GO:0071824;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;regulation of DNA-templated transcription#GO:0006355;cellular component organization#GO:0016043;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA metabolic process#GO:0051252;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;protein-containing complex organization#GO:0043933;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;chromatin organization#GO:0006325;positive regulation of RNA metabolic process#GO:0051254;chromatin remodeling#GO:0006338;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 histone acetyltransferase complex#GO:0000123;acetyltransferase complex#GO:1902493;protein-DNA complex#GO:0032993;catalytic complex#GO:1902494;chromatin#GO:0000785;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein acetyltransferase complex#GO:0031248;protein-containing complex#GO:0032991;chromosome#GO:0005694 Notch signaling pathway#P00045>CoA#P01100 CIOIN|Ensembl=ENSCING00000014069.2|UniProtKB=F6QK67 F6QK67 PTHR42643:SF24 IONOTROPIC RECEPTOR 20A-RELATED IONOTROPIC RECEPTOR 60A transmembrane signal receptor#PC00197 CIOIN|Ensembl=ENSCING00000012614.2|UniProtKB=F6ZKF6 F6ZKF6 PTHR20920:SF5 RPE-SPONDIN SMB DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000008899.3|UniProtKB=F6QEZ7 F6QEZ7 LOC100181588 PTHR12756:SF12 CYTOSOLIC CARBOXYPEPTIDASE CYTOSOLIC CARBOXYPEPTIDASE-LIKE PROTEIN 5 metalloprotease#PC00153;protease#PC00190 CIOIN|Ensembl=ENSCING00000019191.1|UniProtKB=H2XXU6 H2XXU6 hlx PTHR24331:SF0 DBX DBX regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 CIOIN|Ensembl=ENSCING00000005905.3|UniProtKB=F6SHF2 F6SHF2 dmrt1 PTHR12322:SF116 DOUBLESEX AND MAB-3 RELATED TRANSCRIPTION FACTOR DMRT DOUBLESEX-MAB RELATED 99B sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;sex differentiation#GO:0007548;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;developmental process involved in reproduction#GO:0003006;regulation of primary metabolic process#GO:0080090;reproduction#GO:0000003;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;reproductive process#GO:0022414;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218 CIOIN|Ensembl=ENSCING00000001100.3|UniProtKB=F7AGH4 F7AGH4 PTHR11214:SF283 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE N-ACETYLLACTOSAMINIDE BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE 4-LIKE transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;protein O-linked glycosylation#GO:0006493;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 bounding membrane of organelle#GO:0098588;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;Golgi membrane#GO:0000139;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111 CIOIN|Ensembl=ENSCING00000020403.1|UniProtKB=H2XN66 H2XN66 PTHR34400:SF4 FAMILY NOT NAMED MEMBRANE PROTEIN CIOIN|Ensembl=ENSCING00000003417.1|UniProtKB=F6ZM98 F6ZM98 PTHR21456:SF1 FAMILY WITH SEQUENCE SIMILARITY 102 C2 NT-TYPE DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000012039.2|UniProtKB=F7AN36 F7AN36 PTHR12369:SF13 CHONDROITIN SYNTHASE HEXOSYLTRANSFERASE transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;UDP-glycosyltransferase activity#GO:0008194 glycoprotein biosynthetic process#GO:0009101;glycosaminoglycan metabolic process#GO:0030203;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;chondroitin sulfate proteoglycan biosynthetic process#GO:0050650;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;proteoglycan metabolic process#GO:0006029;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;proteoglycan biosynthetic process#GO:0030166;nitrogen compound metabolic process#GO:0006807;aminoglycan biosynthetic process#GO:0006023;glycosaminoglycan biosynthetic process#GO:0006024;aminoglycan metabolic process#GO:0006022;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 glycosyltransferase#PC00111 CIOIN|Ensembl=ENSCING00000020838.1|UniProtKB=H2XV01 H2XV01 PTHR22906:SF43 PROPERDIN PROPERDIN CIOIN|Ensembl=ENSCING00000020269.1|UniProtKB=H2Y1W2 H2Y1W2 PTHR22903:SF8 PLEKHH PROTEIN MAX-1A Axon guidance mediated by netrin#P00009>MAX-1#P00365 CIOIN|Ensembl=ENSCING00000002469.3|UniProtKB=F7B4Q5 F7B4Q5 PTHR14773:SF0 WD REPEAT-CONTAINING PROTEIN 76 WD REPEAT-CONTAINING PROTEIN 76 nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;regulation of cellular response to stress#GO:0080135;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;regulation of signaling#GO:0023051;biological regulation#GO:0065007;regulation of cell cycle phase transition#GO:1901987;regulation of response to stress#GO:0080134;regulation of cell cycle#GO:0051726;regulation of intracellular signal transduction#GO:1902531;regulation of cell cycle process#GO:0010564 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000007924.3|UniProtKB=F7AA01 F7AA01 PTHR11069:SF23 GLUCOSYLCERAMIDASE LYSOSOMAL ACID GLUCOSYLCERAMIDASE hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;carbohydrate derivative catabolic process#GO:1901136;glycolipid metabolic process#GO:0006664;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;lipid catabolic process#GO:0016042;cellular process#GO:0009987;liposaccharide metabolic process#GO:1903509;sphingolipid metabolic process#GO:0006665;primary metabolic process#GO:0044238;ceramide metabolic process#GO:0006672;membrane lipid metabolic process#GO:0006643;nitrogen compound metabolic process#GO:0006807;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;cellular lipid metabolic process#GO:0044255;sphingolipid catabolic process#GO:0030149;cellular lipid catabolic process#GO:0044242;amide metabolic process#GO:0043603;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 CIOIN|Ensembl=ENSCING00000019978.1|UniProtKB=H2XWD7 H2XWD7 PTHR24256:SF545 TRYPTASE-RELATED INACTIVE SERINE PROTEASE 54 hydrolase activity#GO:0016787;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 serine protease#PC00203;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000004788.3|UniProtKB=H2Y1H7 H2Y1H7 PTHR13619:SF0 PHOSPHATIDATE CYTIDYLYLTRANSFERASE, MITOCHONDRIAL PHOSPHATIDATE CYTIDYLYLTRANSFERASE, MITOCHONDRIAL transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779 lipid metabolic process#GO:0006629;phospholipid biosynthetic process#GO:0008654;organophosphate biosynthetic process#GO:0090407;glycerolipid biosynthetic process#GO:0045017;cardiolipin biosynthetic process#GO:0032049;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;glycerophospholipid metabolic process#GO:0006650;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;glycerophospholipid biosynthetic process#GO:0046474;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000000989.3|UniProtKB=F6YLR6 F6YLR6 LOC100176958 PTHR10334:SF554 CYSTEINE-RICH SECRETORY PROTEIN-RELATED AT04879P-RELATED extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 defense/immunity protein#PC00090 CIOIN|Ensembl=ENSCING00000003288.3|UniProtKB=F6WMZ2 F6WMZ2 PTHR23086:SF46 PHOSPHATIDYLINOSITOL-4-PHOSPHATE 5-KINASE PHOSPHATIDYLINOSITOL 4-PHOSPHATE 5-KINASE-LIKE PROTEIN 1 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301;lipid kinase activity#GO:0001727 lipid metabolic process#GO:0006629;phospholipid biosynthetic process#GO:0008654;organophosphate biosynthetic process#GO:0090407;phosphatidylinositol biosynthetic process#GO:0006661;glycerolipid biosynthetic process#GO:0045017;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;phosphatidylinositol metabolic process#GO:0046488;glycerophospholipid metabolic process#GO:0006650;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;phosphatidylinositol phosphate biosynthetic process#GO:0046854;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;glycerophospholipid biosynthetic process#GO:0046474;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 kinase#PC00137 CIOIN|Ensembl=ENSCING00000005747.3|UniProtKB=F6PZL2 F6PZL2 zf(u1like)-4 PTHR15577:SF2 ZINC FINGER CONTAINING PROTEIN ZINC FINGER PROTEIN 318 positive regulation of nitrogen compound metabolic process#GO:0051173;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;positive regulation of RNA biosynthetic process#GO:1902680;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;positive regulation of cellular metabolic process#GO:0031325;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of DNA-templated transcription#GO:0045892;positive regulation of biological process#GO:0048518;negative regulation of cellular process#GO:0048523;negative regulation of biosynthetic process#GO:0009890;regulation of DNA-templated transcription#GO:0006355;negative regulation of metabolic process#GO:0009892;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;positive regulation of RNA metabolic process#GO:0051254;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000011622.2|UniProtKB=F7AQC2 F7AQC2 LOC100187499 PTHR43243:SF105 INNER MEMBRANE TRANSPORTER YGJI-RELATED CATIONIC AMINO ACID TRANSPORTER C-TERMINAL DOMAIN-CONTAINING PROTEIN transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;amino acid transmembrane transporter activity#GO:0015171;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215;organic acid transmembrane transporter activity#GO:0005342 localization#GO:0051179;organic substance transport#GO:0071702;establishment of localization#GO:0051234;amino acid transport#GO:0006865;organic anion transport#GO:0015711;organic acid transport#GO:0015849;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 amino acid transporter#PC00046;transporter#PC00227 CIOIN|Ensembl=ENSCING00000008181.3|UniProtKB=F6PNT4 F6PNT4 PTHR45892:SF1 AMINOACYLASE-1 AMINOACYLASE-1 hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824 CIOIN|Ensembl=ENSCING00000023268.1|UniProtKB=H2XUR3 H2XUR3 LOC100185305 PTHR11913:SF12 COFILIN-RELATED COFILIN_ACTIN-DEPOLYMERIZING FACTOR HOMOLOG-RELATED cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 cellular component organization or biogenesis#GO:0071840;cellular component disassembly#GO:0022411;actin filament-based process#GO:0030029;protein-containing complex disassembly#GO:0032984;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;actin polymerization or depolymerization#GO:0008154;cellular component organization#GO:0016043;protein depolymerization#GO:0051261;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987;actin filament depolymerization#GO:0030042 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165 Cytoskeletal regulation by Rho GTPase#P00016>Cofilin#P00508 CIOIN|Ensembl=ENSCING00000012488.2|UniProtKB=F6W8H6 F6W8H6 PTHR24300:SF404 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 2D6-LIKE oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;tetrapyrrole binding#GO:0046906;steroid hydroxylase activity#GO:0008395;oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497;heme binding#GO:0020037 response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;response to chemical#GO:0042221;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 oxygenase#PC00177;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000006307.3|UniProtKB=F6UBS1 F6UBS1 PTHR21580:SF57 SHIPPO-1-RELATED OUTER DENSE FIBER OF SPERM TAILS 3-LIKE 2-RELATED intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 structural protein#PC00211 CIOIN|Ensembl=ENSCING00000008543.3|UniProtKB=F6XQ30 F6XQ30 PTHR11616:SF289 SODIUM/CHLORIDE DEPENDENT TRANSPORTER TRANSPORTER secondary active monocarboxylate transmembrane transporter activity#GO:0015355;inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;organic acid:sodium symporter activity#GO:0005343;organic acid transmembrane transporter activity#GO:0005342;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;chloride transmembrane transporter activity#GO:0015108;organic anion transmembrane transporter activity#GO:0008514;monoatomic cation transmembrane transporter activity#GO:0008324;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;amino acid:sodium symporter activity#GO:0005283;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;metal ion transmembrane transporter activity#GO:0046873;active monoatomic ion transmembrane transporter activity#GO:0022853;monoatomic anion transmembrane transporter activity#GO:0008509;monocarboxylic acid transmembrane transporter activity#GO:0008028;amino acid transmembrane transporter activity#GO:0015171;inorganic anion transmembrane transporter activity#GO:0015103;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;organic anion transport#GO:0015711;amino acid transport#GO:0006865;organic acid transport#GO:0015849;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;localization#GO:0051179;organic substance transport#GO:0071702;sodium ion transport#GO:0006814;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;sodium ion transmembrane transport#GO:0035725 cell projection#GO:0042995;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 primary active transporter#PC00068;transporter#PC00227 CIOIN|Ensembl=ENSCING00000003269.3|UniProtKB=F6WNU7 F6WNU7 LOC100178220 PTHR31058:SF2 ZINC FINGER C4H2 DOMAIN-CONTAINING PROTEIN ZINC FINGER C4H2 DOMAIN-CONTAINING PROTEIN regulation of biological process#GO:0050789;positive regulation of cell differentiation#GO:0045597;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of cell differentiation#GO:0045595;positive regulation of biological process#GO:0048518;regulation of neuron differentiation#GO:0045664;positive regulation of developmental process#GO:0051094;positive regulation of cellular process#GO:0048522 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000005763.3|UniProtKB=F6PUJ2 F6PUJ2 PTHR24039:SF58 FIBRILLIN-RELATED EGF-LIKE DOMAIN-CONTAINING PROTEIN extracellular matrix structural protein#PC00103 CIOIN|Ensembl=ENSCING00000015206.2|UniProtKB=F7AAF9 F7AAF9 LOC100184106 PTHR12243:SF63 MADF DOMAIN TRANSCRIPTION FACTOR LD26477P regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218 CIOIN|Ensembl=ENSCING00000005379.3|UniProtKB=F7BEE9 F7BEE9 PTHR20946:SF0 SANT AND BTB DOMAIN REGULATOR OF CLASS SWITCH RECOMBINATION SANT AND BTB DOMAIN REGULATOR OF CLASS SWITCH RECOMBINATION CIOIN|Ensembl=ENSCING00000015202.2|UniProtKB=F6X9U7 F6X9U7 PTHR45782:SF4 MITOCHONDRIAL RIBOSOME-ASSOCIATED GTPASE 1 MITOCHONDRIAL RIBOSOME-ASSOCIATED GTPASE 1 GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;translation#GO:0006412;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 CIOIN|Ensembl=ENSCING00000008644.3|UniProtKB=F6ZYU7 F6ZYU7 LOC100181995 PTHR31698:SF7 LYSOZYME G FAMILY MEMBER PEPTIDASE M15C DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000010518.3|UniProtKB=F6SUP0 F6SUP0 PTHR48041:SF63 ABC TRANSPORTER G FAMILY MEMBER 28 EARLY GENE AT 23, ISOFORM C transmembrane transporter activity#GO:0022857;primary active transmembrane transporter activity#GO:0015399;ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 localization#GO:0051179;cellular process#GO:0009987;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 ATP-binding cassette (ABC) transporter#PC00003;transporter#PC00227 CIOIN|Ensembl=ENSCING00000003984.3|UniProtKB=F6WKL8 F6WKL8 LOC100180175 PTHR24251:SF37 OVOCHYMASE-RELATED CUB DOMAIN-CONTAINING PROTEIN serine protease#PC00203;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000021196.1|UniProtKB=H2XWZ7 H2XWZ7 PTHR12480:SF41 ARGININE DEMETHYLASE AND LYSYL-HYDROXYLASE JMJD JMJC DOMAIN-CONTAINING PROTEIN sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;dioxygenase activity#GO:0051213;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity#GO:0016491 positive regulation of gene expression#GO:0010628;positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of protein metabolic process#GO:0051246;regulation of amide metabolic process#GO:0034248;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;protein modification process#GO:0036211;regulation of cellular component organization#GO:0051128;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;protein hydroxylation#GO:0018126;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;positive regulation of biological process#GO:0048518;positive regulation of translation#GO:0045727;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;regulation of protein-containing complex disassembly#GO:0043244;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;positive regulation of protein metabolic process#GO:0051247;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;post-transcriptional regulation of gene expression#GO:0010608;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;regulation of translation#GO:0006417;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000005630.3|UniProtKB=F7A961 F7A961 PTHR12385:SF14 CHOLINE TRANSPORTER-LIKE (SLC FAMILY 44) CHOLINE TRANSPORTER-LIKE 2 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 localization#GO:0051179;establishment of localization#GO:0051234;cellular process#GO:0009987;transmembrane transport#GO:0055085;transport#GO:0006810 cellular anatomical entity#GO:0110165;membrane#GO:0016020 secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000014146.2|UniProtKB=F7ARP7 F7ARP7 PTHR22588:SF3 VWFA DOMAIN-CONTAINING PROTEIN VWFA DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000011663.2|UniProtKB=F6X986 F6X986 PTHR23147:SF189 SERINE/ARGININE RICH SPLICING FACTOR SERINE AND ARGININE-RICH-SPLICING FACTOR 3A nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;nuclear speck#GO:0016607;organelle#GO:0043226;nuclear body#GO:0016604;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA splicing factor#PC00148;RNA processing factor#PC00147;RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000009489.3|UniProtKB=F6W3Q3 F6W3Q3 PTHR13964:SF27 RBP-RELATED HAT-TRICK, ISOFORM D sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transcription cofactor#PC00217 CIOIN|Ensembl=ENSCING00000002953.3|UniProtKB=F6R8A8 F6R8A8 PTHR24028:SF328 CADHERIN-87A CADHERIN-3 cell adhesion#GO:0007155;cellular process#GO:0009987 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cell adhesion molecule#PC00069;cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 CIOIN|Ensembl=ENSCING00000012658.2|UniProtKB=F6U4S4 F6U4S4 PTHR12243:SF60 MADF DOMAIN TRANSCRIPTION FACTOR SI:CH211-15D5.12-RELATED regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218 CIOIN|Ensembl=ENSCING00000006942.3|UniProtKB=F6VMY2 F6VMY2 LOC100176126 PTHR24073:SF185 DRAB5-RELATED RAS-RELATED PROTEIN RAB-14 GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824 localization#GO:0051179;organic substance transport#GO:0071702;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;transport#GO:0006810;protein transport#GO:0015031;nitrogen compound transport#GO:0071705;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104 cellular anatomical entity#GO:0110165;endomembrane system#GO:0012505 small GTPase#PC00208;G-protein#PC00020 CIOIN|Ensembl=ENSCING00000020421.1|UniProtKB=H2XJQ7 H2XJQ7 LOC100184780 PTHR13046:SF0 PROTEASE U48 CAAX PRENYL PROTEASE RCE1 CAAX PRENYL PROTEASE 2 hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;protein processing#GO:0016485;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000021629.1|UniProtKB=H2XTY0 H2XTY0 PTHR15827:SF2 CYCLIN-DEPENDENT KINASE 2-INTERACTING PROTEIN CYCLIN-DEPENDENT KINASE 2-INTERACTING PROTEIN Cell cycle#P00013>Cdk2#P00485 CIOIN|Ensembl=ENSCING00000005361.3|UniProtKB=F7BFF4 F7BFF4 LOC100179869 PTHR12900:SF0 MITOTIC AND DNA DAMAGE CHECKPOINT PROTEIN HUS1 CHECKPOINT PROTEIN DNA repair#GO:0006281;DNA damage checkpoint signaling#GO:0000077;mitotic cell cycle checkpoint signaling#GO:0007093;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;cell cycle checkpoint signaling#GO:0000075;DNA damage response#GO:0006974;mitotic cell cycle#GO:0000278;nitrogen compound metabolic process#GO:0006807;recombinational repair#GO:0000725;reproductive process#GO:0022414;intracellular signal transduction#GO:0035556;organic substance metabolic process#GO:0071704;nucleotide-excision repair#GO:0006289;regulation of cell cycle G2/M phase transition#GO:1902749;negative regulation of cell cycle#GO:0045786;regulation of mitotic cell cycle phase transition#GO:1901990;macromolecule metabolic process#GO:0043170;meiotic cell cycle#GO:0051321;regulation of cell cycle phase transition#GO:1901987;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;double-strand break repair via homologous recombination#GO:0000724;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;regulation of cell cycle process#GO:0010564;cellular component organization or biogenesis#GO:0071840;response to stress#GO:0006950;reproduction#GO:0000003;negative regulation of G2/M transition of mitotic cell cycle#GO:0010972;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;mitotic G2/M transition checkpoint#GO:0044818;sexual reproduction#GO:0019953;cellular response to stress#GO:0033554;cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;double-strand break repair#GO:0006302;telomere organization#GO:0032200;mitotic intra-S DNA damage checkpoint signaling#GO:0031573;cell cycle process#GO:0022402;negative regulation of cell cycle process#GO:0010948;mitotic cell cycle process#GO:1903047;telomere maintenance#GO:0000723;negative regulation of mitotic cell cycle phase transition#GO:1901991;organic cyclic compound metabolic process#GO:1901360;meiotic cell cycle process#GO:1903046;signal transduction in response to DNA damage#GO:0042770;mitotic DNA replication checkpoint signaling#GO:0033314;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;negative regulation of cell cycle G2/M phase transition#GO:1902750;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of mitotic cell cycle#GO:0045930;cellular process#GO:0009987;DNA integrity checkpoint signaling#GO:0031570;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;organelle organization#GO:0006996;DNA replication checkpoint signaling#GO:0000076;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;mitotic DNA integrity checkpoint signaling#GO:0044774;regulation of G2/M transition of mitotic cell cycle#GO:0010389;mitotic DNA damage checkpoint signaling#GO:0044773;regulation of mitotic cell cycle#GO:0007346;DNA metabolic process#GO:0006259 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;site of DNA damage#GO:0090734;condensed chromosome#GO:0000793;intracellular organelle lumen#GO:0070013;condensed nuclear chromosome#GO:0000794;site of double-strand break#GO:0035861;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 DNA metabolism protein#PC00009 CIOIN|Ensembl=ENSCING00000019805.1|UniProtKB=F6W7I3 F6W7I3 LOC100181285 PTHR11353:SF24 CHAPERONIN T-COMPLEX PROTEIN 1 SUBUNIT GAMMA protein binding#GO:0005515;unfolded protein binding#GO:0051082;binding#GO:0005488 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein folding#GO:0006457;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;chaperonin-containing T-complex#GO:0005832;protein folding chaperone complex#GO:0101031;intracellular anatomical structure#GO:0005622 chaperonin#PC00073 CIOIN|Ensembl=ENSCING00000003274.4|UniProtKB=F6UFF5 F6UFF5 LOC100180591 PTHR43398:SF1 DOLICHOL-PHOSPHATE MANNOSYLTRANSFERASE SUBUNIT 1 DOLICHOL-PHOSPHATE MANNOSYLTRANSFERASE SUBUNIT 1 mannosyltransferase activity#GO:0000030;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000014116.3|UniProtKB=F6SR47 F6SR47 LOC100177644 PTHR13204:SF1 PTD012 PROTEIN ESTER HYDROLASE C11ORF54 cation binding#GO:0043169;hydrolase activity, acting on ester bonds#GO:0016788;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;zinc ion binding#GO:0008270;transition metal ion binding#GO:0046914;hydrolase activity#GO:0016787;metal ion binding#GO:0046872;ion binding#GO:0043167 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000002288.3|UniProtKB=F6VF53 F6VF53 LOC100178518 PTHR24286:SF252 CYTOCHROME P450 26 CYTOCHROME P450 26B1 oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497 sterol metabolic process#GO:0016125;organic hydroxy compound metabolic process#GO:1901615;lipid metabolic process#GO:0006629;steroid metabolic process#GO:0008202;organic cyclic compound metabolic process#GO:1901360;metabolic process#GO:0008152;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704 oxygenase#PC00177;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000011248.2|UniProtKB=F6TTN6 F6TTN6 LOC100185551 PTHR19282:SF519 TETRASPANIN TETRASPANIN cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000009947.3|UniProtKB=F6R5K2 F6R5K2 PTHR10044:SF139 INHIBITOR OF APOPTOSIS DEATH-ASSOCIATED INHIBITOR OF APOPTOSIS 2 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protease inhibitor#PC00191 CIOIN|Ensembl=ENSCING00000011753.2|UniProtKB=F6TAD8 F6TAD8 PTHR12455:SF0 NUCLEOLAR COMPLEX PROTEIN 4 NUCLEOLAR COMPLEX PROTEIN 4 HOMOLOG membrane-enclosed lumen#GO:0031974;small-subunit processome#GO:0032040;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;preribosome, small subunit precursor#GO:0030688;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;preribosome#GO:0030684;nuclear protein-containing complex#GO:0140513;90S preribosome#GO:0030686 RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000005120.3|UniProtKB=F6ZVK8 F6ZVK8 PTHR11388:SF157 ORGANIC ANION TRANSPORTER SOLUTE CARRIER ORGANIC ANION TRANSPORTER FAMILY MEMBER 2A1-LIKE secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 localization#GO:0051179;organic substance transport#GO:0071702;establishment of localization#GO:0051234;organic anion transport#GO:0015711;transport#GO:0006810 basal plasma membrane#GO:0009925;basolateral plasma membrane#GO:0016323;plasma membrane region#GO:0098590;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;basal part of cell#GO:0045178;plasma membrane#GO:0005886 transporter#PC00227 CIOIN|Ensembl=ENSCING00000004855.3|UniProtKB=F6TCF1 F6TCF1 PTHR22872:SF2 BTK-BINDING PROTEIN-RELATED INHIBITOR OF BRUTON TYROSINE KINASE CIOIN|Ensembl=ENSCING00000005663.3|UniProtKB=F6XDI5 F6XDI5 LOC100187083 PTHR11028:SF0 VACUOLAR ATP SYNTHASE SUBUNIT AC39 V-TYPE PROTON ATPASE SUBUNIT D 1 regulation of intracellular pH#GO:0051453;cellular localization#GO:0051641;vacuolar transport#GO:0007034;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;homeostatic process#GO:0042592;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;cellular process#GO:0009987;intracellular chemical homeostasis#GO:0055082;monoatomic ion homeostasis#GO:0050801;localization#GO:0051179;regulation of pH#GO:0006885;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;intracellular monoatomic cation homeostasis#GO:0030003;biological regulation#GO:0065007;intracellular pH reduction#GO:0051452;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;intracellular monoatomic ion homeostasis#GO:0006873;regulation of cellular pH#GO:0030641;vacuolar acidification#GO:0007035 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;vacuolar membrane#GO:0005774;ATPase complex#GO:1904949;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;proton-transporting two-sector ATPase complex#GO:0016469;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227 ATP synthase#PC00002;primary active transporter#PC00068;transporter#PC00227 CIOIN|Ensembl=ENSCING00000012945.2|UniProtKB=F6RGQ1 F6RGQ1 PTHR45987:SF4 39S RIBOSOMAL PROTEIN L12 LARGE RIBOSOMAL SUBUNIT PROTEIN BL12M structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;RNA binding#GO:0003723;structural molecule activity#GO:0005198;binding#GO:0005488;organic cyclic compound binding#GO:0097159 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;translation#GO:0006412;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 ribosomal protein#PC00202;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000002747.3|UniProtKB=F7AGV3 F7AGV3 PTHR24255:SF38 COMPLEMENT COMPONENT 1, S SUBCOMPONENT-RELATED MANNAN-BINDING LECTIN SERINE PROTEASE 1-LIKE hydrolase activity#GO:0016787;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 serine protease#PC00203;protease#PC00190 CIOIN|Ensembl=ENSCING00000004435.3|UniProtKB=F6Y3D6 F6Y3D6 PTHR11571:SF230 GLUTATHIONE S-TRANSFERASE GLUTATHIONE TRANSFERASE glutathione transferase activity#GO:0004364;transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824 sulfur compound metabolic process#GO:0006790;nitrogen compound metabolic process#GO:0006807;peptide metabolic process#GO:0006518;cellular modified amino acid metabolic process#GO:0006575;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular process#GO:0009987;glutathione metabolic process#GO:0006749;amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000001913.3|UniProtKB=F7A1V5 F7A1V5 LOC100182908 PTHR47958:SF56 ATP-DEPENDENT RNA HELICASE DBP3 RNA HELICASE catalytic activity, acting on RNA#GO:0140098;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;helicase activity#GO:0004386;ATP-dependent activity#GO:0140657;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;catalytic activity, acting on a nucleic acid#GO:0140640;mRNA binding#GO:0003729 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;mRNA splicing, via spliceosome#GO:0000398;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 ribonucleoprotein complex#GO:1990904;catalytic step 2 spliceosome#GO:0071013;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA helicase#PC00032 CIOIN|Ensembl=ENSCING00000018813.1|UniProtKB=H2XPD7 H2XPD7 LOC104266726 PTHR24064:SF577 SOLUTE CARRIER FAMILY 22 MEMBER GH09241P secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000012153.2|UniProtKB=F6UI12 F6UI12 LOC100181865 PTHR12062:SF9 N-ACETYLGLUCOSAMINYLTRANSFERASE VI ALPHA-1,3-MANNOSYL-GLYCOPROTEIN 4-BETA-N-ACETYLGLUCOSAMINYLTRANSFERASE A, ISOFORM A acetylglucosaminyltransferase activity#GO:0008375;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;UDP-glycosyltransferase activity#GO:0008194 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein N-linked glycosylation#GO:0006487;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;Golgi apparatus subcompartment#GO:0098791;cellular anatomical entity#GO:0110165;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;Golgi stack#GO:0005795;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000007224.3|UniProtKB=F6VL68 F6VL68 LOC100178496 PTHR46636:SF1 CDK2-ASSOCIATED AND CULLIN DOMAIN-CONTAINING PROTEIN 1 CDK2-ASSOCIATED AND CULLIN DOMAIN-CONTAINING PROTEIN 1 enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;binding#GO:0005488;kinase binding#GO:0019900 positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;mitotic cell cycle phase transition#GO:0044772;regulation of nitrogen compound metabolic process#GO:0051171;cell cycle G1/S phase transition#GO:0044843;positive regulation of cellular metabolic process#GO:0031325;cell cycle process#GO:0022402;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;positive regulation of protein modification process#GO:0031401;mitotic cell cycle process#GO:1903047;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;G1/S transition of mitotic cell cycle#GO:0000082;mitotic cell cycle#GO:0000278;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;regulation of molecular function#GO:0065009;positive regulation of biological process#GO:0048518;regulation of kinase activity#GO:0043549;regulation of protein kinase activity#GO:0045859;positive regulation of protein phosphorylation#GO:0001934;positive regulation of phosphorylation#GO:0042327;positive regulation of catalytic activity#GO:0043085;positive regulation of phosphorus metabolic process#GO:0010562;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;cell cycle phase transition#GO:0044770;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;positive regulation of protein metabolic process#GO:0051247;positive regulation of phosphate metabolic process#GO:0045937;regulation of macromolecule metabolic process#GO:0060255;positive regulation of protein kinase activity#GO:0045860;regulation of cellular process#GO:0050794;regulation of protein phosphorylation#GO:0001932;biological regulation#GO:0065007;cell cycle#GO:0007049;positive regulation of kinase activity#GO:0033674;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 CIOIN|Ensembl=ENSCING00000001476.3|UniProtKB=F6TIA8 F6TIA8 PTHR13369:SF0 FAMILY NOT NAMED GLUTATHIONE S-TRANSFERASE C-TERMINAL DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000006429.3|UniProtKB=F6QR18 F6QR18 PTHR22710:SF2 X-RAY RADIATION RESISTANCE ASSOCIATED PROTEIN 1 XRRA1 X-RAY RADIATION RESISTANCE-ASSOCIATED PROTEIN 1 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000006877.3|UniProtKB=F6YV39 F6YV39 LOC100176981 PTHR21016:SF1 BETA-AMYLOID BINDING PROTEIN-RELATED TM2 DOMAIN-CONTAINING PROTEIN 1 CIOIN|Ensembl=ENSCING00000002374.3|UniProtKB=F6R012 F6R012 LOC100182328 PTHR46066:SF2 CHITINASE DOMAIN-CONTAINING PROTEIN 1 FAMILY MEMBER CHITINASE DOMAIN-CONTAINING PROTEIN 1 CIOIN|Ensembl=ENSCING00000019941.1|UniProtKB=H2XQW6 H2XQW6 LOC100187116 PTHR22911:SF6 ACYL-MALONYL CONDENSING ENZYME-RELATED SOLUTE CARRIER FAMILY 35 MEMBER G1 cellular anatomical entity#GO:0110165;membrane#GO:0016020 transporter#PC00227 CIOIN|Ensembl=ENSCING00000008743.3|UniProtKB=F6T113 F6T113 LOC100184807 PTHR24039:SF52 FIBRILLIN-RELATED EGF-LIKE DOMAIN-CONTAINING PROTEIN extracellular matrix structural protein#PC00103 CIOIN|Ensembl=ENSCING00000007016.3|UniProtKB=F7AEJ4 F7AEJ4 LOC100181274 PTHR13498:SF3 SPERM ASSOCIATED ANTIGEN 7 SPERM-ASSOCIATED ANTIGEN 7 DNA metabolism protein#PC00009 CIOIN|Ensembl=ENSCING00000012074.2|UniProtKB=F6YHK2 F6YHK2 LOC100187527 PTHR46688:SF1 ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 16 ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 16 CIOIN|Ensembl=ENSCING00000001743.3|UniProtKB=F7AMK6 F7AMK6 PTHR42985:SF45 SODIUM-COUPLED MONOCARBOXYLATE TRANSPORTER SODIUM_IODIDE COTRANSPORTER-LIKE symporter activity#GO:0015293;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 localization#GO:0051179;monoatomic cation transport#GO:0006812;sodium ion transport#GO:0006814;metal ion transport#GO:0030001;establishment of localization#GO:0051234;monoatomic ion transport#GO:0006811;transport#GO:0006810 secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000001393.3|UniProtKB=F6ZTT9 F6ZTT9 PTHR22906:SF46 PROPERDIN HEMICENTIN-1-LIKE CIOIN|Ensembl=ENSCING00000008857.3|UniProtKB=H2XPG3 H2XPG3 PTHR12750:SF9 DIPHOSPHOINOSITOL PENTAKISPHOSPHATE KINASE INOSITOL HEXAKISPHOSPHATE AND DIPHOSPHOINOSITOL-PENTAKISPHOSPHATE KINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;phosphotransferase activity, phosphate group as acceptor#GO:0016776 organic hydroxy compound metabolic process#GO:1901615;organophosphate biosynthetic process#GO:0090407;alcohol biosynthetic process#GO:0046165;cellular metabolic process#GO:0044237;alcohol metabolic process#GO:0006066;organic hydroxy compound biosynthetic process#GO:1901617;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;organophosphate metabolic process#GO:0019637;small molecule biosynthetic process#GO:0044283;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 nucleotide kinase#PC00172;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000006273.3|UniProtKB=F6V2A4 F6V2A4 LOC100184129 PTHR10333:SF42 INHIBITOR OF GROWTH PROTEIN INHIBITOR OF GROWTH PROTEIN 5 protein binding#GO:0005515;methylated histone binding#GO:0035064;binding#GO:0005488;histone binding#GO:0042393;modification-dependent protein binding#GO:0140030 chromatin/chromatin-binding, or -regulatory protein#PC00077 CIOIN|Ensembl=ENSCING00000003187.3|UniProtKB=F6SQE9 F6SQE9 LOC100183827 PTHR21506:SF0 COMPONENT OF OLIGOMERIC GOLGI COMPLEX 6 CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 6 localization#GO:0051179;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization#GO:0051234;Golgi vesicle transport#GO:0048193;intra-Golgi vesicle-mediated transport#GO:0006891;transport#GO:0006810 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;vesicle tethering complex#GO:0099023;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;Golgi transport complex#GO:0017119;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000022166.1|UniProtKB=H2XVI8 H2XVI8 LOC100182799 PTHR20899:SF1 PIERCE HOMOLOG PIERCER OF MICROTUBULE WALL 1 PROTEIN CIOIN|Ensembl=ENSCING00000004075.3|UniProtKB=Q4H3E0 Q4H3E0 Ci-HMG1_2 PTHR48112:SF32 HIGH MOBILITY GROUP PROTEIN DSP1 HIGH MOBILITY GROUP PROTEIN B3 HMG box transcription factor#PC00024 CIOIN|Ensembl=ENSCING00000019259.1|UniProtKB=H2XP11 H2XP11 LOC100185837 PTHR10877:SF183 POLYCYSTIN FAMILY MEMBER AT14535P-RELATED ion channel#PC00133;transporter#PC00227 CIOIN|Ensembl=ENSCING00000012765.2|UniProtKB=F6ZQ96 F6ZQ96 prd-b PTHR46271:SF4 HOMEOBOX PROTEIN, PUTATIVE-RELATED HOMEOBOX PROTEIN, PUTATIVE-RELATED sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 homeodomain transcription factor#PC00119 CIOIN|Ensembl=ENSCING00000006739.3|UniProtKB=F6Y025 F6Y025 PTHR10362:SF7 HISTIDINE AMMONIA-LYASE HISTIDINE AMMONIA-LYASE lyase activity#GO:0016829;catalytic activity#GO:0003824 lyase#PC00144 CIOIN|Ensembl=ENSCING00000006415.3|UniProtKB=F6QS52 F6QS52 PTHR22298:SF29 ENDO-1,4-BETA-GLUCANASE ENDOGLUCANASE CIOIN|Ensembl=ENSCING00000004009.3|UniProtKB=F6VXQ6 F6VXQ6 PTHR24343:SF304 SERINE/THREONINE KINASE PROTEIN KINASE DOMAIN-CONTAINING PROTEIN transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;phosphorylation#GO:0016310;protein phosphorylation#GO:0006468;cellular process#GO:0009987;protein metabolic process#GO:0019538;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000001601.3|UniProtKB=F6RZU6 F6RZU6 LOC100177488 PTHR19411:SF0 PROTEIN BUD31-RELATED PROTEIN BUD31 HOMOLOG cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA splicing factor#PC00148;RNA processing factor#PC00147;RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000022678.1|UniProtKB=H2Y3H1 H2Y3H1 PTHR11984:SF53 CONNEXIN GAP JUNCTION PROTEIN wide pore channel activity#GO:0022829;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;channel activity#GO:0015267 biological regulation#GO:0065007;regulation of biological process#GO:0050789;cell communication#GO:0007154;cellular process#GO:0009987;cell-cell signaling#GO:0007267;signaling#GO:0023052 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 cell junction protein#PC00070;gap junction#PC00105 CIOIN|Ensembl=ENSCING00000020894.1|UniProtKB=H2XJK4 H2XJK4 LOC100187227 PTHR34444:SF1 LOC361192 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 90 CIOIN|Ensembl=ENSCING00000004344.3|UniProtKB=F7BMQ6 F7BMQ6 LOC100175600 PTHR22691:SF1 YEAST SPT2-RELATED CENTROSOMAL PROTEIN CCDC61 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;microtubule cytoskeleton#GO:0015630;ciliary basal body#GO:0036064;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cilium#GO:0005929;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 CIOIN|Ensembl=ENSCING00000009492.3|UniProtKB=F6Y9G2 F6Y9G2 PTHR15711:SF65 RAP GTPASE-ACTIVATING PROTEIN RAPGAP_RANGAP DOMAIN-CONTAINING PROTEIN GTPase-activating protein#PC00257 CIOIN|Ensembl=ENSCING00000012405.2|UniProtKB=F6YQ21 F6YQ21 PTHR12329:SF16 BCL2-ASSOCIATED ATHANOGENE BAG FAMILY MOLECULAR CHAPERONE REGULATOR 1 nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;molecular function regulator activity#GO:0098772;nucleoside phosphate binding#GO:1901265;protein binding#GO:0005515;heterocyclic compound binding#GO:1901363;protein-folding chaperone binding#GO:0051087 biological regulation#GO:0065007;regulation of protein stability#GO:0031647;regulation of biological quality#GO:0065008;protein stabilization#GO:0050821 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 chaperone#PC00072 Apoptosis signaling pathway#P00006>Bag#P00278 CIOIN|Ensembl=ENSCING00000007797.3|UniProtKB=F6X3B3 F6X3B3 MED4 PTHR13208:SF2 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 4 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 4 molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;protein-macromolecule adaptor activity#GO:0030674 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;core mediator complex#GO:0070847;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031;general transcription factor#PC00259 CIOIN|Ensembl=ENSCING00000019107.1|UniProtKB=H2XLN7 H2XLN7 PTHR28629:SF4 TRIOKINASE/FMN CYCLASE TRIOKINASE_FMN CYCLASE transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301 organic hydroxy compound metabolic process#GO:1901615;small molecule catabolic process#GO:0044282;carbohydrate catabolic process#GO:0016052;catabolic process#GO:0009056;alcohol metabolic process#GO:0006066;organic substance catabolic process#GO:1901575;carbohydrate metabolic process#GO:0005975;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 cyclase#PC00079;lyase#PC00144 CIOIN|Ensembl=ENSCING00000001893.3|UniProtKB=F7AKQ9 F7AKQ9 PTHR14453:SF67 PARP/ZINC FINGER CCCH TYPE DOMAIN CONTAINING PROTEIN POLY [ADP-RIBOSE] POLYMERASE molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714;protein-macromolecule adaptor activity#GO:0030674 negative regulation of gene expression#GO:0010629;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of biosynthetic process#GO:0009890;negative regulation of metabolic process#GO:0009892;regulation of biological process#GO:0050789;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000007828.3|UniProtKB=F6WTW2 F6WTW2 LOC100179153 PTHR12655:SF0 ACYL-COA THIOESTERASE ACYL-COENZYME A THIOESTERASE 9, MITOCHONDRIAL hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;fatty acyl-CoA hydrolase activity#GO:0047617;catalytic activity#GO:0003824;thiolester hydrolase activity#GO:0016790 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;acyl-CoA metabolic process#GO:0006637;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;amide metabolic process#GO:0043603;purine nucleotide metabolic process#GO:0006163;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;nucleobase-containing small molecule metabolic process#GO:0055086 esterase#PC00097 CIOIN|Ensembl=ENSCING00000005303.3|UniProtKB=F7BQ75 F7BQ75 PTHR11347:SF111 CYCLIC NUCLEOTIDE PHOSPHODIESTERASE CAMP AND CAMP-INHIBITED CGMP 3',5'-CYCLIC PHOSPHODIESTERASE 10A hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;cyclic-nucleotide phosphodiesterase activity#GO:0004112;phosphoric diester hydrolase activity#GO:0008081;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;negative regulation of response to stimulus#GO:0048585;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;cell communication#GO:0007154;cellular process#GO:0009987;regulation of intracellular signal transduction#GO:1902531;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648;cAMP-mediated signaling#GO:0019933;cyclic-nucleotide-mediated signaling#GO:0019935 phosphodiesterase#PC00185 CIOIN|Ensembl=ENSCING00000001562.3|UniProtKB=F6VZQ1 F6VZQ1 PTHR10578:SF107 S -2-HYDROXY-ACID OXIDASE-RELATED 2-HYDROXYACID OXIDASE 1 oxidoreductase#PC00176 ATP synthesis#P02721>FMN FeS#P02792 CIOIN|Ensembl=ENSCING00000002075.2|UniProtKB=A0A1W5BM90 A0A1W5BM90 LOC100179413 PTHR43205:SF7 PROSTAGLANDIN REDUCTASE PROSTAGLANDIN REDUCTASE 1 reductase#PC00198;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000004352.3|UniProtKB=F7B4T0 F7B4T0 PTHR10921:SF1 NUCLEAR DISTRIBUTION PROTEIN NUDE HOMOLOG 1 NUCLEAR DISTRIBUTION PROTEIN NUDE HOMOLOG cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 vesicle transport along microtubule#GO:0047496;establishment or maintenance of cell polarity#GO:0007163;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;nuclear division#GO:0000280;transport#GO:0006810;establishment of spindle orientation#GO:0051294;cell cycle process#GO:0022402;microtubule-based movement#GO:0007018;microtubule cytoskeleton organization#GO:0000226;protein-containing complex assembly#GO:0065003;centrosome cycle#GO:0007098;microtubule cytoskeleton organization involved in mitosis#GO:1902850;microtubule polymerization or depolymerization#GO:0031109;mitotic cell cycle process#GO:1903047;chromosome segregation#GO:0007059;establishment of cell polarity#GO:0030010;mitotic cell cycle#GO:0000278;microtubule polymerization#GO:0046785;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;supramolecular fiber organization#GO:0097435;cytoskeleton-dependent intracellular transport#GO:0030705;cytoskeleton organization#GO:0007010;mitotic nuclear division#GO:0140014;establishment of organelle localization#GO:0051656;spindle localization#GO:0051653;cellular component assembly#GO:0022607;establishment of chromosome localization#GO:0051303;vesicle localization#GO:0051648;cellular component organization#GO:0016043;cellular process#GO:0009987;microtubule organizing center organization#GO:0031023;establishment of spindle localization#GO:0051293;transport along microtubule#GO:0010970;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of mitotic spindle localization#GO:0040001;establishment of mitotic spindle orientation#GO:0000132;microtubule-based transport#GO:0099111;microtubule-based process#GO:0007017;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;centrosome localization#GO:0051642;protein polymerization#GO:0051258;cell cycle#GO:0007049;establishment of localization in cell#GO:0051649;organelle fission#GO:0048285;intracellular transport#GO:0046907;chromosome localization#GO:0050000;microtubule nucleation#GO:0007020;organelle transport along microtubule#GO:0072384;vesicle cytoskeletal trafficking#GO:0099518 supramolecular complex#GO:0099080;microtubule organizing center#GO:0005815;kinetochore#GO:0000776;condensed chromosome, centromeric region#GO:0000779;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;chromosome#GO:0005694;microtubule cytoskeleton#GO:0015630;chromosomal region#GO:0098687;cytoskeleton#GO:0005856 CIOIN|Ensembl=ENSCING00000014200.1|UniProtKB=F6ZPM0 F6ZPM0 PTHR43223:SF2 ALKYL/ARYL-SULFATASE METALLO-BETA-LACTAMASE DOMAIN-CONTAINING PROTEIN metabolite interconversion enzyme#PC00262;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000003404.3|UniProtKB=F6Z4F9 F6Z4F9 PTHR19325:SF567 COMPLEMENT COMPONENT-RELATED SUSHI DOMAIN-CONTAINING SUSHI, VON WILLEBRAND FACTOR TYPE A, EGF AND PENTRAXIN DOMAIN-CONTAINING PROTEIN 1-LIKE complement component#PC00078 CIOIN|Ensembl=ENSCING00000009954.3|UniProtKB=F6R5A5 F6R5A5 LOC100182565 PTHR14725:SF0 RIBOSOME-BINDING FACTOR A, MITOCHONDRIAL-RELATED RIBOSOME-BINDING FACTOR A, MITOCHONDRIAL-RELATED CIOIN|Ensembl=ENSCING00000008012.3|UniProtKB=F6SSX2 F6SSX2 LOC100176888 PTHR11963:SF23 LEUCINE AMINOPEPTIDASE-RELATED CYTOSOL AMINOPEPTIDASE hydrolase activity#GO:0016787;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 metalloprotease#PC00153;protease#PC00190 CIOIN|Ensembl=ENSCING00000012768.2|UniProtKB=F6ZQ39 F6ZQ39 zf(c2h2)-86 PTHR12718:SF2 CELL CYCLE CONTROL PROTEIN CWF15 SPLICEOSOME-ASSOCIATED PROTEIN CWC15 HOMOLOG nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;mRNA cis splicing, via spliceosome#GO:0045292;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704 ribonucleoprotein complex#GO:1990904;catalytic step 2 spliceosome#GO:0071013;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000013057.2|UniProtKB=F6T505 F6T505 PTHR10426:SF88 STRICTOSIDINE SYNTHASE-RELATED ADIPOCYTE PLASMA MEMBRANE-ASSOCIATED PROTEIN HEMOMUCIN-RELATED hydrolase activity#GO:0016787;catalytic activity#GO:0003824 CIOIN|Ensembl=ENSCING00000000625.3|UniProtKB=F6RRN2 F6RRN2 fgf4_5_6 PTHR11486:SF160 FIBROBLAST GROWTH FACTOR FIBROBLAST GROWTH FACTOR 22-LIKE ISOFORM X1 molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;binding#GO:0005488;growth factor activity#GO:0008083;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;growth factor receptor binding#GO:0070851;protein binding#GO:0005515;signaling receptor binding#GO:0005102;fibroblast growth factor receptor binding#GO:0005104 positive regulation of gene expression#GO:0010628;regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;positive regulation of cell population proliferation#GO:0008284;positive regulation of protein modification process#GO:0031401;regulation of intracellular signal transduction#GO:1902531;response to fibroblast growth factor#GO:0071774;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;regulation of cell migration#GO:0030334;anatomical structure morphogenesis#GO:0009653;regulation of signal transduction#GO:0009966;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;cellular developmental process#GO:0048869;cellular response to endogenous stimulus#GO:0071495;positive regulation of phosphorus metabolic process#GO:0010562;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;positive regulation of cell communication#GO:0010647;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;fibroblast growth factor receptor signaling pathway#GO:0008543;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;regulation of locomotion#GO:0040012;response to growth factor#GO:0070848;animal organ development#GO:0048513;regulation of signaling#GO:0023051;developmental process#GO:0032502;positive regulation of MAPK cascade#GO:0043410;positive regulation of response to stimulus#GO:0048584;positive regulation of biosynthetic process#GO:0009891;cell differentiation#GO:0030154;response to endogenous stimulus#GO:0009719;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of intracellular signal transduction#GO:1902533;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;signaling#GO:0023052;regulation of cell communication#GO:0010646;positive regulation of protein phosphorylation#GO:0001934;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;regulation of cell population proliferation#GO:0042127;regulation of cell motility#GO:2000145;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;cellular response to growth factor stimulus#GO:0071363;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;animal organ morphogenesis#GO:0009887;cellular response to fibroblast growth factor stimulus#GO:0044344 cytoplasm#GO:0005737;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576;intracellular anatomical structure#GO:0005622 intercellular signal molecule#PC00207;growth factor#PC00112 CIOIN|Ensembl=ENSCING00000000524.3|UniProtKB=F6VCH9 F6VCH9 LOC100178170 PTHR12302:SF2 EBNA2 BINDING PROTEIN P100 STAPHYLOCOCCAL NUCLEASE DOMAIN-CONTAINING PROTEIN 1 hydrolase activity, acting on ester bonds#GO:0016788;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;nuclease activity#GO:0004518;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;heterocycle catabolic process#GO:0046700;RNA metabolic process#GO:0016070;nucleobase-containing compound metabolic process#GO:0006139;cellular nitrogen compound catabolic process#GO:0044270;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;mRNA catabolic process#GO:0006402;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;organic substance catabolic process#GO:1901575;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;negative regulation of biosynthetic process#GO:0009890;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;nucleobase-containing compound catabolic process#GO:0034655;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000005538.3|UniProtKB=F6Y321 F6Y321 PTHR19957:SF424 SYNTAXIN SYNTAXIN-1A molecular adaptor activity#GO:0060090;protein binding#GO:0005515;SNAP receptor activity#GO:0005484;binding#GO:0005488;SNARE binding#GO:0000149;protein-macromolecule adaptor activity#GO:0030674 vesicle fusion#GO:0006906;cellular localization#GO:0051641;organelle localization#GO:0051640;macromolecule localization#GO:0033036;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;membrane fusion#GO:0061025;exocytosis#GO:0006887;establishment of localization#GO:0051234;organelle organization#GO:0006996;secretion#GO:0046903;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;vesicle organization#GO:0016050;intracellular transport#GO:0046907;export from cell#GO:0140352;secretion by cell#GO:0032940;organelle fusion#GO:0048284 cytoplasm#GO:0005737;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;SNARE complex#GO:0031201;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 SNARE protein#PC00034;membrane traffic protein#PC00150 Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>SNARE Complex#P01066;Nicotinic acetylcholine receptor signaling pathway#P00044>SNARE Complex#P01091;Metabotropic glutamate receptor group II pathway#P00040>SNARE Complex#P01049;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>SNARE Complex#P01079 CIOIN|Ensembl=ENSCING00000020882.1|UniProtKB=F6S880 F6S880 PTHR43157:SF31 PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN-RELATED PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000019501.1|UniProtKB=H2XW34 H2XW34 LOC101243042 PTHR10671:SF96 EPITHELIAL MEMBRANE PROTEIN-RELATED CLC-LIKE PROTEIN 5 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cytoskeletal protein#PC00085 CIOIN|Ensembl=ENSCING00000016877.2|UniProtKB=F6Q7J8 F6Q7J8 PTHR11929:SF145 ALPHA- 1,3 -FUCOSYLTRANSFERASE ALPHA-(1,3)-FUCOSYLTRANSFERASE FUT-1 transferase activity#GO:0016740;fucosyltransferase activity#GO:0008417;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 glycosylation#GO:0070085;metabolic process#GO:0008152 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000001146.3|UniProtKB=F6YTW2 F6YTW2 PTHR24240:SF192 OPSIN C-TYPE OPSIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 response to light stimulus#GO:0009416;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;detection of stimulus#GO:0051606;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;regulation of cellular process#GO:0050794;response to radiation#GO:0009314;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;response to abiotic stimulus#GO:0009628;signaling#GO:0023052;cellular response to light stimulus#GO:0071482 9+0 non-motile cilium#GO:0097731;non-motile cilium#GO:0097730;neuron projection#GO:0043005;photoreceptor outer segment#GO:0001750;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;cilium#GO:0005929;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 CIOIN|Ensembl=ENSCING00000006316.3|UniProtKB=F6RRW9 F6RRW9 LOC100180214 PTHR10082:SF60 INTEGRIN BETA SUBUNIT INTEGRIN BETA-PS cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;integrin binding#GO:0005178;binding#GO:0005488;signaling receptor binding#GO:0005102 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cell adhesion mediated by integrin#GO:0033627;cell-cell adhesion#GO:0098609;cell motility#GO:0048870;cell adhesion#GO:0007155;cell communication#GO:0007154;cell-substrate adhesion#GO:0031589;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cell-matrix adhesion#GO:0007160;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;integrin-mediated signaling pathway#GO:0007229;cell migration#GO:0016477;signaling#GO:0023052 receptor complex#GO:0043235;membrane protein complex#GO:0098796;cell surface#GO:0009986;protein-containing complex#GO:0032991;plasma membrane signaling receptor complex#GO:0098802;anchoring junction#GO:0070161;plasma membrane protein complex#GO:0098797;focal adhesion#GO:0005925;cell junction#GO:0030054;cell-substrate junction#GO:0030055;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cell adhesion molecule#PC00069;integrin#PC00126 Integrin signalling pathway#P00034>Integrin beta#P00931 CIOIN|Ensembl=ENSCING00000005338.3|UniProtKB=F7B4X6 F7B4X6 LOC100185940 PTHR10805:SF0 COATOMER SUBUNIT EPSILON COATOMER SUBUNIT EPSILON localization#GO:0051179;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;intra-Golgi vesicle-mediated transport#GO:0006891;establishment of localization#GO:0051234;transport#GO:0006810;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;coated vesicle#GO:0030135;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;vesicle coat#GO:0030120;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;Golgi-associated vesicle membrane#GO:0030660;protein-containing complex#GO:0032991;COPI vesicle coat#GO:0030126;endomembrane system#GO:0012505;membrane coat#GO:0030117;coated vesicle membrane#GO:0030662;COPI-coated vesicle#GO:0030137;Golgi-associated vesicle#GO:0005798;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;coated membrane#GO:0048475;cytoplasmic vesicle membrane#GO:0030659 vesicle coat protein#PC00235 CIOIN|Ensembl=ENSCING00000012798.2|UniProtKB=F6WQL4 F6WQL4 PTHR23334:SF69 CCAAT/ENHANCER BINDING PROTEIN CCAAT_ENHANCER-BINDING PROTEIN GAMMA sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 DNA-binding transcription factor#PC00218;basic leucine zipper transcription factor#PC00056 CIOIN|Ensembl=ENSCING00000007926.3|UniProtKB=F7A9Y8 F7A9Y8 LOC100182816 PTHR45646:SF11 SERINE/THREONINE-PROTEIN KINASE DOA-RELATED SERINE_THREONINE-PROTEIN KINASE DOA transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;phosphorylation#GO:0016310;protein phosphorylation#GO:0006468;cellular process#GO:0009987;protein metabolic process#GO:0019538;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000006913.3|UniProtKB=F6Y9W9 F6Y9W9 PTHR46342:SF1 ALPHA-CATULIN ALPHA-CATULIN regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;small GTPase-mediated signal transduction#GO:0007264;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;cellular process#GO:0009987;signaling#GO:0023052;Rho protein signal transduction#GO:0007266 Wnt signaling pathway#P00057>alpha-catenin#P01471 CIOIN|Ensembl=ENSCING00000003931.3|UniProtKB=F7A573 F7A573 LOC100176448 PTHR35069:SF1 PROTEIN C9ORF135 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 95 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 CIOIN|Ensembl=ENSCING00000018594.1|UniProtKB=H2XMM0 H2XMM0 PTHR23320:SF158 MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MS4A -RELATED CREB-BINDING PROTEIN-LIKE ISOFORM X1 transporter#PC00227 CIOIN|Ensembl=ENSCING00000004115.3|UniProtKB=F6XUD5 F6XUD5 PTHR13693:SF2 CLASS II AMINOTRANSFERASE/8-AMINO-7-OXONONANOATE SYNTHASE SERINE PALMITOYLTRANSFERASE 1 palmitoyltransferase activity#GO:0016409;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824 organic hydroxy compound metabolic process#GO:1901615;lipid metabolic process#GO:0006629;alcohol biosynthetic process#GO:0046165;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic hydroxy compound biosynthetic process#GO:1901617;alcohol metabolic process#GO:0006066;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;membrane lipid biosynthetic process#GO:0046467;sphingolipid metabolic process#GO:0006665;primary metabolic process#GO:0044238;ceramide metabolic process#GO:0006672;amide biosynthetic process#GO:0043604;membrane lipid metabolic process#GO:0006643;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;ceramide biosynthetic process#GO:0046513;small molecule biosynthetic process#GO:0044283;cellular lipid metabolic process#GO:0044255;amide metabolic process#GO:0043603;sphingolipid biosynthetic process#GO:0030148;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transaminase#PC00216;transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000008291.3|UniProtKB=F6QCS6 F6QCS6 PTHR24393:SF15 ZINC FINGER PROTEIN IP01243P-RELATED DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 CIOIN|Ensembl=ENSCING00000007037.2|UniProtKB=F6ZVV7 F6ZVV7 LOC100182871 PTHR22911:SF6 ACYL-MALONYL CONDENSING ENZYME-RELATED SOLUTE CARRIER FAMILY 35 MEMBER G1 cellular anatomical entity#GO:0110165;membrane#GO:0016020 transporter#PC00227 CIOIN|Ensembl=ENSCING00000004594.3|UniProtKB=F6WPE0 F6WPE0 PTHR22588:SF3 VWFA DOMAIN-CONTAINING PROTEIN VWFA DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000019528.1|UniProtKB=F7A3S4 F7A3S4 PTHR20855:SF15 ADIPOR/PROGESTIN RECEPTOR-RELATED PROGESTIN AND ADIPOQ RECEPTOR FAMILY MEMBER 3 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 G-protein coupled receptor#PC00021 CIOIN|Ensembl=ENSCING00000018587.1|UniProtKB=H2XKG9 H2XKG9 PTHR24372:SF77 GLYCOPROTEIN HORMONE RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 response to organic substance#GO:0010033;positive regulation of adenylate cyclase activity#GO:0045762;regulation of lyase activity#GO:0051339;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;cellular response to stimulus#GO:0051716;regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;cellular response to endogenous stimulus#GO:0071495;cellular response to chemical stimulus#GO:0070887;positive regulation of catalytic activity#GO:0043085;cellular response to organic substance#GO:0071310;regulation of cyclase activity#GO:0031279;positive regulation of molecular function#GO:0044093;cell communication#GO:0007154;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;positive regulation of cyclase activity#GO:0031281;hormone-mediated signaling pathway#GO:0009755;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to endogenous stimulus#GO:0009719;response to hormone#GO:0009725;cellular response to hormone stimulus#GO:0032870;response to chemical#GO:0042221;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of lyase activity#GO:0051349;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 CIOIN|Ensembl=ENSCING00000009110.3|UniProtKB=F6Q909 F6Q909 PTHR15735:SF12 FCH AND DOUBLE SH3 DOMAINS PROTEIN CDC42-INTERACTING PROTEIN 4, ISOFORM B cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165 CIOIN|Ensembl=ENSCING00000000254.3|UniProtKB=F6SGJ4 F6SGJ4 LOC100181179 PTHR43201:SF5 ACYL-COA SYNTHETASE MEDIUM-CHAIN ACYL-COA LIGASE ACSF2, MITOCHONDRIAL ligase activity#GO:0016874;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877 lipid metabolic process#GO:0006629;oxoacid metabolic process#GO:0043436;fatty acid metabolic process#GO:0006631;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular lipid metabolic process#GO:0044255;organic acid metabolic process#GO:0006082;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 ligase#PC00142;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000008896.3|UniProtKB=F6QF27 F6QF27 LOC100181813 PTHR24247:SF265 5-HYDROXYTRYPTAMINE RECEPTOR MUSCARINIC ACETYLCHOLINE RECEPTOR DM1 signaling receptor activity#GO:0038023;G protein-coupled amine receptor activity#GO:0008227;molecular transducer activity#GO:0060089;neurotransmitter receptor activity#GO:0030594;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 response to organic substance#GO:0010033;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to nitrogen compound#GO:1901699;response to nitrogen compound#GO:1901698;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to oxygen-containing compound#GO:1901701;chemical synaptic transmission#GO:0007268;response to chemical#GO:0042221;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;synaptic signaling#GO:0099536;G protein-coupled receptor signaling pathway#GO:0007186;cell-cell signaling#GO:0007267;signaling#GO:0023052;acetylcholine receptor signaling pathway#GO:0095500 synapse#GO:0045202;somatodendritic compartment#GO:0036477;neuron projection#GO:0043005;cell junction#GO:0030054;dendrite#GO:0030425;cell projection#GO:0042995;cell periphery#GO:0071944;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GqPCR#P00730 CIOIN|Ensembl=ENSCING00000006230.3|UniProtKB=F6YVI2 F6YVI2 LOC100176076 PTHR12585:SF27 SCC1 / RAD21 FAMILY MEMBER MEIOTIC RECOMBINATION PROTEIN REC8 HOMOLOG protein-containing complex binding#GO:0044877;binding#GO:0005488;chromatin binding#GO:0003682 DNA repair#GO:0006281;meiotic sister chromatid cohesion#GO:0051177;cellular aromatic compound metabolic process#GO:0006725;double-strand break repair#GO:0006302;cell cycle process#GO:0022402;nucleobase-containing compound metabolic process#GO:0006139;sister chromatid cohesion#GO:0007062;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;recombinational repair#GO:0000725;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;double-strand break repair via homologous recombination#GO:0000724;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;replication-born double-strand break repair via sister chromatid exchange#GO:1990414;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;chromosome organization#GO:0051276;organelle organization#GO:0006996;cell cycle#GO:0007049;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;cohesin complex#GO:0008278;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000013851.2|UniProtKB=F6XVE4 F6XVE4 PTHR11675:SF119 N-ACETYLGALACTOSAMINYLTRANSFERASE POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE 2 transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;UDP-glycosyltransferase activity#GO:0008194 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;protein O-linked glycosylation#GO:0006493;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000002758.3|UniProtKB=F7AHE1 F7AHE1 LOC100177212 PTHR24073:SF509 DRAB5-RELATED RAS-RELATED PROTEIN RAB-21 GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824 localization#GO:0051179;organic substance transport#GO:0071702;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;transport#GO:0006810;protein transport#GO:0015031;nitrogen compound transport#GO:0071705;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104 cytoplasm#GO:0005737;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular vesicle#GO:0097708;early endosome#GO:0005769;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 small GTPase#PC00208;G-protein#PC00020 CIOIN|Ensembl=ENSCING00000007948.3|UniProtKB=F6ZRA2 F6ZRA2 PTHR13410:SF9 PROTEIN PBDC1 PROTEIN PBDC1 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000013528.2|UniProtKB=F7AI05 F7AI05 PTHR10293:SF16 GLUTAREDOXIN FAMILY MEMBER GLUTAREDOXIN-RELATED PROTEIN 5, MITOCHONDRIAL reductase#PC00198;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000002373.3|UniProtKB=F6R5G5 F6R5G5 PTHR16189:SF0 TRANSMEMBRANE PROTEIN 104-RELATED TRANSMEMBRANE PROTEIN 104 CIOIN|Ensembl=ENSCING00000001782.3|UniProtKB=F6ZKG3 F6ZKG3 PTHR45617:SF170 LEUCINE RICH REPEAT FAMILY PROTEIN MIP14966P scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000011658.2|UniProtKB=F6ZMP6 F6ZMP6 LOC100179562 PTHR13413:SF0 YLP MOTIF CONTAINING PROTEIN NUCLEAR PROTEIN ZAP YLP MOTIF-CONTAINING PROTEIN 1 regulation of biological process#GO:0050789;regulation of chromosome organization#GO:0033044;regulation of primary metabolic process#GO:0080090;regulation of macromolecule metabolic process#GO:0060255;regulation of nitrogen compound metabolic process#GO:0051171;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of DNA metabolic process#GO:0051052;regulation of organelle organization#GO:0033043;biological regulation#GO:0065007;regulation of cellular component organization#GO:0051128;regulation of telomere maintenance#GO:0032204;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA metabolism protein#PC00009 CIOIN|Ensembl=ENSCING00000021985.1|UniProtKB=H2XWB6 H2XWB6 PTHR35352:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 150 COILED-COIL DOMAIN-CONTAINING PROTEIN 150 CIOIN|Ensembl=ENSCING00000000755.3|UniProtKB=F6PWH7 F6PWH7 LOC100179457 PTHR11138:SF5 METHIONYL-TRNA FORMYLTRANSFERASE METHIONYL-TRNA FORMYLTRANSFERASE, MITOCHONDRIAL catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA modification#GO:0009451;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;tRNA modification#GO:0006400;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 RNA processing factor#PC00147;RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000009831.3|UniProtKB=F6Y4S3 F6Y4S3 LOC100180192 PTHR16049:SF8 IQ DOMAIN-CONTAINING PROTEIN C IQ DOMAIN-CONTAINING PROTEIN C CIOIN|Ensembl=ENSCING00000012427.1|UniProtKB=F6Y549 F6Y549 LOC100186342 PTHR12480:SF41 ARGININE DEMETHYLASE AND LYSYL-HYDROXYLASE JMJD JMJC DOMAIN-CONTAINING PROTEIN sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;dioxygenase activity#GO:0051213;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity#GO:0016491 positive regulation of gene expression#GO:0010628;positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of protein metabolic process#GO:0051246;regulation of amide metabolic process#GO:0034248;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;protein modification process#GO:0036211;regulation of cellular component organization#GO:0051128;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;protein hydroxylation#GO:0018126;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;positive regulation of biological process#GO:0048518;positive regulation of translation#GO:0045727;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;regulation of protein-containing complex disassembly#GO:0043244;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;positive regulation of protein metabolic process#GO:0051247;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;post-transcriptional regulation of gene expression#GO:0010608;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;regulation of translation#GO:0006417;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000005295.3|UniProtKB=F7BPQ7 F7BPQ7 LOC100177361 PTHR13872:SF43 DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT STT3A transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein glycosylation#GO:0006486;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein N-linked glycosylation#GO:0006487;protein metabolic process#GO:0019538;protein N-linked glycosylation via asparagine#GO:0018279;glycosylation#GO:0070085;glycoprotein metabolic process#GO:0009100;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 glycosyltransferase#PC00111 CIOIN|Ensembl=ENSCING00000005819.3|UniProtKB=F6Y7X3 F6Y7X3 PTHR24246:SF27 OLFACTORY RECEPTOR AND ADENOSINE RECEPTOR ADENOSINE RECEPTOR, ISOFORM A G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711 CIOIN|Ensembl=ENSCING00000002802.3|UniProtKB=F6XMP2 F6XMP2 PTHR11003:SF291 POTASSIUM CHANNEL, SUBFAMILY K IP11374P monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated potassium channel activity#GO:0005249;channel activity#GO:0015267;transporter activity#GO:0005215;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;regulation of membrane potential#GO:0042391;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;localization#GO:0051179;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;monoatomic cation transport#GO:0006812;potassium ion transmembrane transport#GO:0071805;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;potassium ion transport#GO:0006813 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 CIOIN|Ensembl=ENSCING00000004309.3|UniProtKB=F6TSI9 F6TSI9 LOC108950261 PTHR47965:SF12 ASPARTYL PROTEASE-RELATED ASPARTIC PROTEINASE 3-RELATED protease#PC00190;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000012188.2|UniProtKB=F6TU56 F6TU56 PTHR19300:SF30 BETA-1,4-GALACTOSYLTRANSFERASE BETA-1,4-GALACTOSYLTRANSFERASE 7 galactosyltransferase activity#GO:0008378;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 glycosylation#GO:0070085;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 Wnt signaling pathway#P00057>Calcineurin#P01446 CIOIN|Ensembl=ENSCING00000024856.1|UniProtKB=H2XRQ7 H2XRQ7 PTHR11214:SF376 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE HEXOSYLTRANSFERASE transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;protein O-linked glycosylation#GO:0006493;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 bounding membrane of organelle#GO:0098588;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;Golgi membrane#GO:0000139;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111 CIOIN|Ensembl=ENSCING00000003707.3|UniProtKB=F6XH38 F6XH38 PTHR11164:SF0 GLUTAMATE CYSTEINE LIGASE GLUTAMATE--CYSTEINE LIGASE CATALYTIC SUBUNIT ligase activity#GO:0016874;catalytic activity#GO:0003824 sulfur compound metabolic process#GO:0006790;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;glutathione metabolic process#GO:0006749;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;cellular modified amino acid metabolic process#GO:0006575;amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 ligase#PC00142;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000019740.1|UniProtKB=H2Y008 H2Y008 LOC100184009 PTHR28661:SF1 SJOEGREN SYNDROME NUCLEAR AUTOANTIGEN 1 MICROTUBULE NUCLEATION FACTOR SSNA1 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;microtubule cytoskeleton#GO:0015630;ciliary basal body#GO:0036064;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cilium#GO:0005929;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000000861.3|UniProtKB=F6SX63 F6SX63 PTHR10036:SF3 CD59 GLYCOPROTEIN PROTEIN SLEEPLESS-RELATED CIOIN|Ensembl=ENSCING00000012929.2|UniProtKB=F6RLP1 F6RLP1 PTHR15504:SF0 NASOPHARYNGEAL EPITHELIUM SPECIFIC PROTEIN 1 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 45 CIOIN|Ensembl=ENSCING00000020161.1|UniProtKB=H2XVF8 H2XVF8 PTHR48015:SF4 SERINE/THREONINE-PROTEIN KINASE TAO SERINE_THREONINE-PROTEIN KINASE PAK MBT transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of MAPK cascade#GO:0043408;signal transduction#GO:0007165;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;regulation of signaling#GO:0023051;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular process#GO:0009987;regulation of intracellular signal transduction#GO:1902531;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PAK#P00837;Cytoskeletal regulation by Rho GTPase#P00016>PAK#P00517 CIOIN|Ensembl=ENSCING00000001070.3|UniProtKB=F7B0Q2 F7B0Q2 LOC100185176 PTHR11588:SF239 TUBULIN TUBULIN ALPHA CHAIN carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;structural molecule activity#GO:0005198;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167;structural constituent of cytoskeleton#GO:0005200 cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;microtubule-based process#GO:0007017;organelle organization#GO:0006996;microtubule cytoskeleton organization#GO:0000226;cytoskeleton organization#GO:0007010;cell cycle#GO:0007049;cellular component organization#GO:0016043;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622 tubulin#PC00228;microtubule or microtubule-binding cytoskeletal protein#PC00157 CIOIN|Ensembl=ENSCING00000008696.3|UniProtKB=F5XVE7 F5XVE7 ci-galp PTHR16839:SF1 GALANIN GALANIN PEPTIDES CIOIN|Ensembl=ENSCING00000007290.3|UniProtKB=F6S8B5 F6S8B5 LOC100179564 PTHR11635:SF152 CAMP-DEPENDENT PROTEIN KINASE REGULATORY CHAIN CAMP-DEPENDENT PROTEIN KINASE TYPE I REGULATORY SUBUNIT-RELATED cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 kinase modulator#PC00140 Metabotropic glutamate receptor group III pathway#P00039>PKA#P01035;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>PKA#P01075;Cell cycle#P00013>Protein kinase subunit#P00482;GABA-B receptor II signaling#P05731>PKA#P05752;5HT1 type receptor mediated signaling pathway#P04373>PKA#P04403;Enkephalin release#P05913>PKA#P05972;Histamine H2 receptor mediated signaling pathway#P04386>PKA#P04491;Dopamine receptor mediated signaling pathway#P05912>PKA#P05946;Transcription regulation by bZIP transcription factor#P00055>PKA#P01384;Beta2 adrenergic receptor signaling pathway#P04378>PKA#P04444;Metabotropic glutamate receptor group II pathway#P00040>PKA#P01050;Hedgehog signaling pathway#P00025>PKA#P00682;Beta1 adrenergic receptor signaling pathway#P04377>PKA#P04437;Metabotropic glutamate receptor group I pathway#P00041>PKA#P01059;Endothelin signaling pathway#P00019>PKA#P00570 CIOIN|Ensembl=ENSCING00000019870.1|UniProtKB=H2XYS7 H2XYS7 LOC100175446 PTHR13206:SF0 UBIQUITIN LIGASE PROTEIN PHF9 FANCONI ANEMIA GROUP L PROTEIN E3 UBIQUITIN-PROTEIN LIGASE FANCL transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;protein ubiquitination#GO:0016567;cellular response to stimulus#GO:0051716;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein monoubiquitination#GO:0006513;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;post-translational protein modification#GO:0043687;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;response to stress#GO:0006950;nitrogen compound metabolic process#GO:0006807;cellular response to stress#GO:0033554;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000020271.1|UniProtKB=H2XVH0 H2XVH0 LOC100176603 PTHR36978:SF4 P-LOOP CONTAINING NUCLEOTIDE TRIPHOSPHATE HYDROLASE P-LOOP CONTAINING NUCLEOSIDE TRIPHOSPHATE HYDROLASE PROTEIN metabolite interconversion enzyme#PC00262;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000024606.1|UniProtKB=H2XQS6 H2XQS6 PTHR13398:SF0 GDP-FUCOSE PROTEIN O-FUCOSYLTRANSFERASE 2 GDP-FUCOSE PROTEIN O-FUCOSYLTRANSFERASE 2 transferase activity#GO:0016740;fucosyltransferase activity#GO:0008417;catalytic activity, acting on a protein#GO:0140096;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000012458.2|UniProtKB=F6UUA2 F6UUA2 PTHR11601:SF62 CYSTEINE DESULFURYLASE FAMILY MEMBER SELENOCYSTEINE LYASE lyase#PC00144 CIOIN|Ensembl=ENSCING00000004359.3|UniProtKB=Q1RL62 Q1RL62 Ci-ZF(C2H2)-145 PTHR24404:SF106 ZINC FINGER PROTEIN C2H2-TYPE DOMAIN-CONTAINING PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 CIOIN|Ensembl=ENSCING00000009020.3|UniProtKB=F6RC10 F6RC10 PTHR14326:SF44 TARGETING PROTEIN FOR XKLP2 TARGETING PROTEIN FOR XKLP2 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 CIOIN|Ensembl=ENSCING00000022116.1|UniProtKB=H2XUM1 H2XUM1 LOC100175445 PTHR16275:SF8 COILED-COIL DOMAIN-CONTAINING PROTEIN 40 COILED-COIL DOMAIN-CONTAINING PROTEIN 40 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000011867.2|UniProtKB=F7BIS6 F7BIS6 PTHR19325:SF567 COMPLEMENT COMPONENT-RELATED SUSHI DOMAIN-CONTAINING SUSHI, VON WILLEBRAND FACTOR TYPE A, EGF AND PENTRAXIN DOMAIN-CONTAINING PROTEIN 1-LIKE complement component#PC00078 CIOIN|Ensembl=ENSCING00000003800.3|UniProtKB=F7AR76 F7AR76 PTHR24300:SF397 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 2U1 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;tetrapyrrole binding#GO:0046906;steroid hydroxylase activity#GO:0008395;oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497;heme binding#GO:0020037 response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;response to chemical#GO:0042221;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 oxygenase#PC00177;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000000724.3|UniProtKB=A0A1W2WJB6 A0A1W2WJB6 LOC100179184 PTHR23289:SF2 CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX15 CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX15 HOMOLOG chaperone#PC00072 Vitamin D metabolism and pathway#P04396>FDX#P04607 CIOIN|Ensembl=ENSCING00000016140.2|UniProtKB=F6SUJ3 F6SUJ3 LOC778542 PTHR13935:SF106 ACHAETE-SCUTE TRANSCRIPTION FACTOR-RELATED ACHAETE-SCUTE COMPLEX PROTEIN T5-RELATED sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;basic helix-loop-helix transcription factor#PC00055 CIOIN|Ensembl=ENSCING00000011960.2|UniProtKB=F6UKC4 F6UKC4 LOC100184797 PTHR43636:SF2 ELONGATION FACTOR G, MITOCHONDRIAL ELONGATION FACTOR G, MITOCHONDRIAL GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;translation regulator activity#GO:0045182;nucleic acid binding#GO:0003676;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;translation regulator activity, nucleic acid binding#GO:0090079;translation elongation factor activity#GO:0003746;translation factor activity, RNA binding#GO:0008135 CIOIN|Ensembl=ENSCING00000009911.3|UniProtKB=F6RAE8 F6RAE8 LOC100176638 PTHR14383:SF5 SWAP-70 RECOMBINASE RUN DOMAIN-CONTAINING PROTEIN scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000014438.2|UniProtKB=F6TXM9 F6TXM9 PTHR45678:SF5 MITOCHONDRIAL 2-OXODICARBOXYLATE CARRIER 1-RELATED AT03939P-RELATED L-glutamate transmembrane transporter activity#GO:0005313;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;organic acid transmembrane transporter activity#GO:0005342;L-amino acid transmembrane transporter activity#GO:0015179;organic anion transmembrane transporter activity#GO:0008514;amino acid transmembrane transporter activity#GO:0015171;transporter activity#GO:0005215;acidic amino acid transmembrane transporter activity#GO:0015172 cellular respiration#GO:0045333;L-amino acid transport#GO:0015807;transmembrane transport#GO:0055085;dicarboxylic acid transport#GO:0006835;organic anion transport#GO:0015711;acidic amino acid transport#GO:0015800;amino acid transport#GO:0006865;organic acid transport#GO:0015849;transport#GO:0006810;generation of precursor metabolites and energy#GO:0006091;nitrogen compound transport#GO:0071705;electron transport chain#GO:0022900;carboxylic acid transport#GO:0046942;cellular metabolic process#GO:0044237;cellular process#GO:0009987;energy derivation by oxidation of organic compounds#GO:0015980;carboxylic acid transmembrane transport#GO:1905039;localization#GO:0051179;mitochondrial transport#GO:0006839;organic substance transport#GO:0071702;amino acid transmembrane transport#GO:0003333;establishment of localization#GO:0051234;L-alpha-amino acid transmembrane transport#GO:1902475;respiratory electron transport chain#GO:0022904;C4-dicarboxylate transport#GO:0015740;aspartate transmembrane transport#GO:0015810;organic acid transmembrane transport#GO:1903825;mitochondrial transmembrane transport#GO:1990542;metabolic process#GO:0008152 secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000007706.3|UniProtKB=F7A2R6 F7A2R6 PTHR20661:SF0 PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS W PROTEIN PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS W PROTEIN transferase activity#GO:0016740;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;O-acyltransferase activity#GO:0008374 lipid metabolic process#GO:0006629;cellular localization#GO:0051641;carbohydrate derivative metabolic process#GO:1901135;phospholipid biosynthetic process#GO:0008654;macromolecule localization#GO:0033036;macromolecule modification#GO:0043412;phosphatidylinositol biosynthetic process#GO:0006661;organophosphate biosynthetic process#GO:0090407;glycolipid metabolic process#GO:0006664;protein modification process#GO:0036211;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;lipid biosynthetic process#GO:0008610;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;protein lipidation#GO:0006497;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;protein localization to plasma membrane#GO:0072659;localization within membrane#GO:0051668;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein localization to membrane#GO:0072657;glycerolipid biosynthetic process#GO:0045017;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;glycerophospholipid metabolic process#GO:0006650;phosphatidylinositol metabolic process#GO:0046488;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;liposaccharide metabolic process#GO:1903509;membrane lipid biosynthetic process#GO:0046467;GPI anchor metabolic process#GO:0006505;lipoprotein biosynthetic process#GO:0042158;primary metabolic process#GO:0044238;protein localization#GO:0008104;localization#GO:0051179;carbohydrate derivative biosynthetic process#GO:1901137;GPI anchor biosynthetic process#GO:0006506;protein localization to cell periphery#GO:1990778;cellular macromolecule localization#GO:0070727;membrane lipid metabolic process#GO:0006643;glycerophospholipid biosynthetic process#GO:0046474;glycolipid biosynthetic process#GO:0009247;organophosphate metabolic process#GO:0019637;lipoprotein metabolic process#GO:0042157;cellular lipid metabolic process#GO:0044255 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 acyltransferase#PC00042;transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000011618.2|UniProtKB=F7AQJ2 F7AQJ2 PTHR24033:SF193 EGF-LIKE DOMAIN-CONTAINING PROTEIN NETRIN-G1-RELATED Axon guidance mediated by netrin#P00009>Netrin#P00357;Axon guidance mediated by Slit/Robo#P00008>Netrin#P00344 CIOIN|Ensembl=ENSCING00000006080.3|UniProtKB=F6ZG04 F6ZG04 PTHR10584:SF166 SUGAR KINASE RIBOKINASE transferase#PC00220;metabolite interconversion enzyme#PC00262;carbohydrate kinase#PC00065 CIOIN|Ensembl=ENSCING00000007433.3|UniProtKB=F7APM6 F7APM6 PTHR23167:SF54 CALPONIN HOMOLOGY DOMAIN-CONTAINING PROTEIN DDB_G0272472-RELATED [F-ACTIN]-MONOOXYGENASE MICAL scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000006717.3|UniProtKB=F6YLJ0 F6YLJ0 LOC100176912 PTHR42985:SF45 SODIUM-COUPLED MONOCARBOXYLATE TRANSPORTER SODIUM_IODIDE COTRANSPORTER-LIKE symporter activity#GO:0015293;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 localization#GO:0051179;monoatomic cation transport#GO:0006812;sodium ion transport#GO:0006814;metal ion transport#GO:0030001;establishment of localization#GO:0051234;monoatomic ion transport#GO:0006811;transport#GO:0006810 secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000010308.3|UniProtKB=F6PPL2 F6PPL2 PTHR11801:SF43 SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION SIGNAL TRANSDUCER AND TRANSCRIPTION ACTIVATOR sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;Rel homology transcription factor#PC00252;immunoglobulin fold transcription factor#PC00251 PDGF signaling pathway#P00047>STAT#P01173;EGF receptor signaling pathway#P00018>STAT#P00561 CIOIN|Ensembl=ENSCING00000002175.2|UniProtKB=F6SSG7 F6SSG7 PTHR11447:SF16 CELLULAR TUMOR ANTIGEN P53 P53 PROTEIN LONG FORM VARIANT 1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 P53-like transcription factor#PC00253;immunoglobulin fold transcription factor#PC00251 Huntington disease#P00029>p53#P00797 CIOIN|Ensembl=ENSCING00000000743.3|UniProtKB=F6Q1G7 F6Q1G7 PTHR45644:SF3 AAA ATPASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12920)-RELATED-RELATED FI08533P-RELATED envelope#GO:0031975;bounding membrane of organelle#GO:0098588;mitochondrial membrane#GO:0031966;intracellular membrane-bounded organelle#GO:0043231;mitochondrial outer membrane#GO:0005741;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867 CIOIN|Ensembl=ENSCING00000005028.3|UniProtKB=F6TAR1 F6TAR1 PTHR10353:SF36 GLYCOSYL HYDROLASE LP05116P hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;glucosidase activity#GO:0015926;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 glycosidase#PC00110;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000001776.3|UniProtKB=F6X618 F6X618 PTHR13011:SF0 TFIIF-ALPHA GENERAL TRANSCRIPTION FACTOR IIF SUBUNIT 1 basal RNA polymerase II transcription machinery binding#GO:0001099;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;basal transcription machinery binding#GO:0001098;transcription factor binding#GO:0008134;binding#GO:0005488 cellular aromatic compound metabolic process#GO:0006725;DNA-templated transcription#GO:0006351;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;RNA biosynthetic process#GO:0032774;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;transcription initiation at RNA polymerase II promoter#GO:0006367;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nucleobase-containing compound biosynthetic process#GO:0034654;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;DNA-templated transcription initiation#GO:0006352;aromatic compound biosynthetic process#GO:0019438;transcription by RNA polymerase II#GO:0006366;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;DNA-directed RNA polymerase complex#GO:0000428;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695;RNA polymerase II, holoenzyme#GO:0016591;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;transcription regulator complex#GO:0005667;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 RNA metabolism protein#PC00031;general transcription factor#PC00259 General transcription regulation#P00023>TFIIFalpha#P00663;Transcription regulation by bZIP transcription factor#P00055>TFIIFalpha#P01391 CIOIN|Ensembl=ENSCING00000007102.3|UniProtKB=F6VLS5 F6VLS5 PTHR12011:SF471 ADHESION G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 2 PROFILE 2 DOMAIN-CONTAINING PROTEIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 CIOIN|Ensembl=ENSCING00000004313.1|UniProtKB=Q8MXX3 Q8MXX3 blcap PTHR13259:SF1 BLADDER CANCER 10 KD PROTEIN HOMOLOG BLADDER CANCER-ASSOCIATED PROTEIN CIOIN|Ensembl=ENSCING00000020171.1|UniProtKB=H2XSN4 H2XSN4 PTHR45742:SF8 COMPLEMENT COMPONENT C6 FLOCCULATION PROTEIN FLO11 complement component#PC00078 CIOIN|Ensembl=ENSCING00000023597.1|UniProtKB=H2XWR9 H2XWR9 LOC100186045 PTHR11748:SF111 D-LACTATE DEHYDROGENASE D-LACTATE DEHYDROGENASE, MITOCHONDRIAL-RELATED nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;flavin adenine dinucleotide binding#GO:0050660;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;anion binding#GO:0043168;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 organic hydroxy compound metabolic process#GO:1901615;oxoacid metabolic process#GO:0043436;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;monocarboxylic acid catabolic process#GO:0072329 dehydrogenase#PC00092;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000003422.3|UniProtKB=F6XL93 F6XL93 PTHR11453:SF47 ANION EXCHANGE PROTEIN ANION EXCHANGE PROTEIN transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 localization#GO:0051179;organic substance transport#GO:0071702;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;organic anion transport#GO:0015711;transport#GO:0006810;homeostatic process#GO:0042592;chemical homeostasis#GO:0048878;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000020330.1|UniProtKB=H2Y1V3 H2Y1V3 PTHR45948:SF2 DUAL SPECIFICITY PROTEIN PHOSPHATASE DDB_G0269404-RELATED DUAL SPECIFICITY PROTEIN PHOSPHATASE hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;protein tyrosine phosphatase activity#GO:0004725;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;dephosphorylation#GO:0016311;biological regulation#GO:0065007;cellular metabolic process#GO:0044237;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052;phosphorus metabolic process#GO:0006793;metabolic process#GO:0008152;phosphate-containing compound metabolic process#GO:0006796 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 protein phosphatase#PC00195;protein modifying enzyme#PC00260 Oxidative stress response#P00046>MKP5#P01131 CIOIN|Ensembl=ENSCING00000013744.2|UniProtKB=F6RQK4 F6RQK4 PTHR35559:SF1 CHITIN-BINDING TYPE-4 DOMAIN-CONTAINING PROTEIN CHITIN-BINDING TYPE-4 DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000013854.2|UniProtKB=F6QGN1 F6QGN1 PTHR10918:SF5 HOMER HOMER, ISOFORM E protein binding#GO:0005515;G protein-coupled receptor binding#GO:0001664;binding#GO:0005488;signaling receptor binding#GO:0005102 signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of metal ion transport#GO:0010959;regulation of localization#GO:0032879;regulation of calcium ion transport#GO:0051924;cell communication#GO:0007154;cellular process#GO:0009987;glutamate receptor signaling pathway#GO:0007215;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of transport#GO:0051049;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;regulation of monoatomic ion transport#GO:0043269;signaling#GO:0023052 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 CIOIN|Ensembl=ENSCING00000005677.3|UniProtKB=F6XD32 F6XD32 PTHR31437:SF1 SREK1IP1 FAMILY MEMBER PROTEIN SREK1IP1 CIOIN|Ensembl=ENSCING00000019254.1|UniProtKB=H2XT35 H2XT35 PTHR22588:SF3 VWFA DOMAIN-CONTAINING PROTEIN VWFA DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000001488.3|UniProtKB=F6THR3 F6THR3 PTHR23121:SF9 SODIUM-DEPENDENT GLUCOSE TRANSPORTER 1 SODIUM-DEPENDENT GLUCOSE TRANSPORTER 1 transmembrane transporter activity#GO:0022857;sugar transmembrane transporter activity#GO:0051119;transporter activity#GO:0005215;carbohydrate transmembrane transporter activity#GO:0015144 transporter#PC00227 CIOIN|Ensembl=ENSCING00000001749.3|UniProtKB=F7AMD9 F7AMD9 PTHR12176:SF80 SAM-DEPENDENT METHYLTRANSFERASE SUPERFAMILY PROTEIN EEF1A LYSINE METHYLTRANSFERASE 4 methyltransferase#PC00155 CIOIN|Ensembl=ENSCING00000005510.3|UniProtKB=F7AUP3 F7AUP3 LOC100176187 PTHR43968:SF6 FAMILY NOT NAMED GLUTATHIONE S-TRANSFERASE OMEGA cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000008046.3|UniProtKB=F6S4X9 F6S4X9 LOC100176443 PTHR46612:SF1 XYLOSIDE XYLOSYLTRANSFERASE 1 XYLOSIDE XYLOSYLTRANSFERASE 1 UDP-xylosyltransferase activity#GO:0035252;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;xylosyltransferase activity#GO:0042285;pentosyltransferase activity#GO:0016763;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;protein O-linked glycosylation#GO:0006493;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000002368.3|UniProtKB=F6SRH9 F6SRH9 LOC113475085 PTHR12461:SF27 HYPOXIA-INDUCIBLE FACTOR 1 ALPHA INHIBITOR-RELATED JMJC DOMAIN-CONTAINING PROTEIN protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000015552.2|UniProtKB=F6SLD6 F6SLD6 PTHR11085:SF9 NAD-DEPENDENT PROTEIN DEACYLASE SIRTUIN-5, MITOCHONDRIAL-RELATED NAD-DEPENDENT PROTEIN DEACETYLASE SIRTUIN-1 nucleotide binding#GO:0000166;histone modifying activity#GO:0140993;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;deacetylase activity#GO:0019213;histone deacetylase activity#GO:0004407;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;anion binding#GO:0043168;catalytic activity, acting on a protein#GO:0140096 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 p53 pathway#P00059>SIRT-1#P04632 CIOIN|Ensembl=ENSCING00000019289.1|UniProtKB=Q1RL53 Q1RL53 Ci-ZF(C2H2)-148 PTHR33936:SF24 PROTEIN CBG17840 C2H2-TYPE DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000021109.1|UniProtKB=H2XTD5 H2XTD5 PTHR36978:SF4 P-LOOP CONTAINING NUCLEOTIDE TRIPHOSPHATE HYDROLASE P-LOOP CONTAINING NUCLEOSIDE TRIPHOSPHATE HYDROLASE PROTEIN metabolite interconversion enzyme#PC00262;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000011458.1|UniProtKB=F6ZUG2 F6ZUG2 PTHR22906:SF53 PROPERDIN HEMICENTIN-1 CIOIN|Ensembl=ENSCING00000006618.3|UniProtKB=F6QPI8 F6QPI8 LOC100176117 PTHR12353:SF1 DISKS LARGE-ASSOCIATED PROTEIN DAP SAP90/PSD-95-ASSOCIATED PROTEIN DISKS LARGE-ASSOCIATED PROTEIN 5 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000007570.3|UniProtKB=F7AM82 F7AM82 PTHR19134:SF562 RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE PROTEIN-TYROSINE-PHOSPHATASE hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;protein tyrosine phosphatase activity#GO:0004725;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 protein phosphatase#PC00195;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000022308.1|UniProtKB=F7AUS4 F7AUS4 LOC100185848 PTHR11085:SF1 NAD-DEPENDENT PROTEIN DEACYLASE SIRTUIN-5, MITOCHONDRIAL-RELATED NAD-DEPENDENT PROTEIN DEACETYLASE SIRTUIN-7 nucleotide binding#GO:0000166;histone modifying activity#GO:0140993;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;deacetylase activity#GO:0019213;histone deacetylase activity#GO:0004407;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;anion binding#GO:0043168;catalytic activity, acting on a protein#GO:0140096 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000019639.1|UniProtKB=H2XXQ3 H2XXQ3 PTHR24412:SF172 KELCH PROTEIN KELCH-LIKE PROTEIN 10 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000006428.3|UniProtKB=F6QL68 F6QL68 PTHR19134:SF561 RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE PROTEIN TYROSINE PHOSPHATASE 36E, ISOFORM A hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;protein tyrosine phosphatase activity#GO:0004725;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 protein phosphatase#PC00195;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000003587.3|UniProtKB=F6XJD6 F6XJD6 LOC100184124 PTHR24353:SF111 CYCLIC NUCLEOTIDE-DEPENDENT PROTEIN KINASE SUBFAMILY NOT NAMED non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Endothelin signaling pathway#P00019>PKG#P00567 CIOIN|Ensembl=ENSCING00000019625.1|UniProtKB=H2Y2X2 H2Y2X2 c3-1 PTHR11412:SF166 MACROGLOBULIN / COMPLEMENT NTR DOMAIN-CONTAINING PROTEIN protease inhibitor#PC00191 CIOIN|Ensembl=ENSCING00000003851.3|UniProtKB=F6YQ68 F6YQ68 LOC100187213 PTHR24081:SF8 NUCLEAR RECEPTOR SUBFAMILY 0 GROUP B NR LBD DOMAIN-CONTAINING PROTEIN molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;protein binding#GO:0005515;transcription factor binding#GO:0008134 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;regulation of molecular function#GO:0065009;regulation of biosynthetic process#GO:0009889;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;negative regulation of biosynthetic process#GO:0009890;regulation of DNA-binding transcription factor activity#GO:0051090;regulation of DNA-templated transcription#GO:0006355;negative regulation of metabolic process#GO:0009892;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;negative regulation of DNA-binding transcription factor activity#GO:0043433;regulation of cellular metabolic process#GO:0031323;negative regulation of molecular function#GO:0044092 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C4 zinc finger nuclear receptor#PC00169;zinc finger transcription factor#PC00244 CIOIN|Ensembl=ENSCING00000018033.1|UniProtKB=H2XLG0 H2XLG0 PTHR10825:SF72 RING FINGER DOMAIN-CONTAINING, POLYCOMB GROUP COMPONENT UBIQUITIN-LIKE DOMAIN-CONTAINING PROTEIN protein-containing complex binding#GO:0044877;binding#GO:0005488;chromatin binding#GO:0003682 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of biosynthetic process#GO:0009890;negative regulation of RNA metabolic process#GO:0051253;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;nuclear ubiquitin ligase complex#GO:0000152;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;PcG protein complex#GO:0031519;protein-containing complex#GO:0032991;PRC1 complex#GO:0035102;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 chromatin/chromatin-binding, or -regulatory protein#PC00077;histone modifying enzyme#PC00261 CIOIN|Ensembl=ENSCING00000004081.3|UniProtKB=F6ZWW6 F6ZWW6 LOC100185650 PTHR45745:SF1 PHOSPHOMANNOMUTASE 45A PHOSPHOGLUCOMUTASE 2B-RELATED isomerase activity#GO:0016853;intramolecular transferase activity#GO:0016866;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;nucleoside metabolic process#GO:0009116;carbohydrate derivative metabolic process#GO:1901135;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;purine-containing compound biosynthetic process#GO:0072522;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;organic cyclic compound metabolic process#GO:1901360;nucleobase-containing compound biosynthetic process#GO:0034654;purine nucleoside metabolic process#GO:0042278;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;purine-containing compound metabolic process#GO:0072521;aromatic compound biosynthetic process#GO:0019438;small molecule biosynthetic process#GO:0044283;glycosyl compound metabolic process#GO:1901657;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;nucleobase-containing small molecule metabolic process#GO:0055086 mutase#PC00160 CIOIN|Ensembl=ENSCING00000007202.3|UniProtKB=F6Y844 F6Y844 LOC100177342 PTHR21580:SF28 SHIPPO-1-RELATED BOREALIN N-TERMINAL DOMAIN-CONTAINING PROTEIN-RELATED structural protein#PC00211 CIOIN|Ensembl=ENSCING00000015058.2|UniProtKB=F6S809 F6S809 LOC100176475 PTHR11207:SF5 RIBONUCLEASE III LARGE RIBOSOMAL SUBUNIT PROTEIN ML44 catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;nuclease activity#GO:0004518;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;endonuclease activity#GO:0004519;hydrolase activity#GO:0016787;catalytic activity, acting on a nucleic acid#GO:0140640;RNA nuclease activity#GO:0004540;double-stranded RNA binding#GO:0003725;RNA endonuclease activity#GO:0004521 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;RNA metabolic process#GO:0016070;peptide metabolic process#GO:0006518;mitochondrial gene expression#GO:0140053;regulatory ncRNA processing#GO:0070918;RNA processing#GO:0006396;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;translation#GO:0006412;regulation of biological process#GO:0050789;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;miRNA processing#GO:0035196;heterocycle metabolic process#GO:0046483;regulatory ncRNA-mediated gene silencing#GO:0031047;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;mitochondrial translation#GO:0032543;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;negative regulation of metabolic process#GO:0009892;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;primary miRNA processing#GO:0031053;amide biosynthetic process#GO:0043604;negative regulation of macromolecule biosynthetic process#GO:0010558;peptide biosynthetic process#GO:0043043;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;translational elongation#GO:0006414;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;endoribonuclease complex#GO:1902555;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;endonuclease complex#GO:1905348;intracellular organelle lumen#GO:0070013;mitochondrial large ribosomal subunit#GO:0005762;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;mitochondrial ribosome#GO:0005761;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein complex#GO:1990904;organellar ribosome#GO:0000313;protein-containing complex#GO:0032991;large ribosomal subunit#GO:0015934;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;ribosome#GO:0005840;nuclear protein-containing complex#GO:0140513;mitochondrial protein-containing complex#GO:0098798 endoribonuclease#PC00094;RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000004231.3|UniProtKB=F6YGF8 F6YGF8 LOC100183089 PTHR11097:SF9 EXOSOME COMPLEX EXONUCLEASE RIBOSOMAL RNA PROCESSING PROTEIN EXOSOME COMPLEX COMPONENT RRP43 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159;mRNA 3'-UTR binding#GO:0003730 negative regulation of gene expression#GO:0010629;tRNA metabolic process#GO:0006399;cellular component biogenesis#GO:0044085;regulation of catabolic process#GO:0009894;heterocycle catabolic process#GO:0046700;regulation of nitrogen compound metabolic process#GO:0051171;rRNA processing#GO:0006364;positive regulation of cellular metabolic process#GO:0031325;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;RNA destabilization#GO:0050779;modification-dependent macromolecule catabolic process#GO:0043632;regulation of biological process#GO:0050789;ncRNA metabolic process#GO:0034660;mRNA metabolic process#GO:0016071;regulation of biological quality#GO:0065008;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;snRNA 3'-end processing#GO:0034472;ribosome biogenesis#GO:0042254;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;regulation of RNA stability#GO:0043487;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;positive regulation of mRNA catabolic process#GO:0061014;regulation of cellular process#GO:0050794;rRNA metabolic process#GO:0016072;post-transcriptional regulation of gene expression#GO:0010608;positive regulation of catabolic process#GO:0009896;mRNA destabilization#GO:0061157;nucleobase-containing compound catabolic process#GO:0034655;polyadenylation-dependent ncRNA catabolic process#GO:0043634;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of mRNA stability#GO:0043488;regulation of mRNA catabolic process#GO:0061013;RNA metabolic process#GO:0016070;positive regulation of cellular catabolic process#GO:0031331;RNA processing#GO:0006396;biosynthetic process#GO:0009058;cellular nitrogen compound catabolic process#GO:0044270;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;mRNA catabolic process#GO:0006402;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;snRNA processing#GO:0016180;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance catabolic process#GO:1901575;maturation of 5.8S rRNA#GO:0000460;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;positive regulation of mRNA metabolic process#GO:1903313;heterocycle metabolic process#GO:0046483;snRNA metabolic process#GO:0016073;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;RNA 3'-end processing#GO:0031123;cellular biosynthetic process#GO:0044249;nuclear-transcribed mRNA catabolic process#GO:0000956;organic substance biosynthetic process#GO:1901576;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;aromatic compound catabolic process#GO:0019439;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;ribonucleoprotein complex biogenesis#GO:0022613;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;positive regulation of RNA metabolic process#GO:0051254 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513;exosome (RNase complex)#GO:0000178 RNA metabolism protein#PC00031;exoribonuclease#PC00099 CIOIN|Ensembl=ENSCING00000013953.2|UniProtKB=F6RQ34 F6RQ34 PTHR21427:SF19 UBIQUINONE BIOSYNTHESIS PROTEIN COQ9, MITOCHONDRIAL UBIQUINONE BIOSYNTHESIS PROTEIN COQ9, MITOCHONDRIAL lipid binding#GO:0008289;binding#GO:0005488 cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;small molecule biosynthetic process#GO:0044283;ubiquinone biosynthetic process#GO:0006744;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 envelope#GO:0031975;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227 CIOIN|Ensembl=ENSCING00000000538.3|UniProtKB=F6RWB6 F6RWB6 PTHR22906:SF43 PROPERDIN PROPERDIN CIOIN|Ensembl=ENSCING00000009606.3|UniProtKB=F7ADF2 F7ADF2 LOC100177610 PTHR43503:SF4 MCG48959-RELATED PEROXIREDOXIN-6 homeostatic process#GO:0042592;cellular homeostasis#GO:0019725 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 peroxidase#PC00180;oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000025203.1|UniProtKB=Q8HIN6 Q8HIN6 COII PTHR22888:SF9 CYTOCHROME C OXIDASE, SUBUNIT II CYTOCHROME C OXIDASE SUBUNIT 2 inorganic molecular entity transmembrane transporter activity#GO:0015318;transmembrane transporter activity#GO:0022857;primary active transmembrane transporter activity#GO:0015399;electron transfer activity#GO:0009055;catalytic activity#GO:0003824;proton transmembrane transporter activity#GO:0015078;active monoatomic ion transmembrane transporter activity#GO:0022853;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;inorganic cation transmembrane transporter activity#GO:0022890;active transmembrane transporter activity#GO:0022804;monoatomic ion transmembrane transporter activity#GO:0015075;oxidoreductase activity#GO:0016491 aerobic respiration#GO:0009060;cellular respiration#GO:0045333;respiratory electron transport chain#GO:0022904;generation of precursor metabolites and energy#GO:0006091;oxidative phosphorylation#GO:0006119;electron transport chain#GO:0022900;ATP synthesis coupled electron transport#GO:0042773;cellular metabolic process#GO:0044237;cellular process#GO:0009987;energy derivation by oxidation of organic compounds#GO:0015980;metabolic process#GO:0008152 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 Gonadotropin-releasing hormone receptor pathway#P06664>COX2#P06734;Gonadotropin-releasing hormone receptor pathway#P06664>COX2#G06686;Gonadotropin-releasing hormone receptor pathway#P06664>COX2#G06899 CIOIN|Ensembl=ENSCING00000011998.2|UniProtKB=H2XKK7 H2XKK7 PTHR45820:SF4 FI23527P1 ZINC TRANSPORTER 63C, ISOFORM F inorganic molecular entity transmembrane transporter activity#GO:0015318;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;inorganic cation transmembrane transporter activity#GO:0022890;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075 inorganic ion homeostasis#GO:0098771;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;homeostatic process#GO:0042592;inorganic ion transmembrane transport#GO:0098660;chemical homeostasis#GO:0048878;cellular process#GO:0009987;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;monoatomic ion homeostasis#GO:0050801;localization#GO:0051179;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation transport#GO:0006812;transition metal ion transport#GO:0000041;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655 cellular anatomical entity#GO:0110165;membrane#GO:0016020 CIOIN|Ensembl=ENSCING00000015692.2|UniProtKB=F6WI94 F6WI94 PTHR22792:SF131 LUPUS LA PROTEIN-RELATED LA-RELATED PROTEIN LARP4B nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159;mRNA 3'-UTR binding#GO:0003730 positive regulation of gene expression#GO:0010628;positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of protein metabolic process#GO:0051246;regulation of amide metabolic process#GO:0034248;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;positive regulation of biosynthetic process#GO:0009891;positive regulation of protein metabolic process#GO:0051247;positive regulation of metabolic process#GO:0009893;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biosynthetic process#GO:0009889;post-transcriptional regulation of gene expression#GO:0010608;positive regulation of macromolecule biosynthetic process#GO:0010557;biological regulation#GO:0065007;regulation of translation#GO:0006417;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of biological process#GO:0048518;positive regulation of translation#GO:0045727;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;cytosol#GO:0005829;cytoplasmic stress granule#GO:0010494;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000018100.1|UniProtKB=H2XK25 H2XK25 PTHR24241:SF188 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR GASTRIN_CHOLECYSTOKININ TYPE B RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;binding#GO:0005488;peptide binding#GO:0042277;transmembrane signaling receptor activity#GO:0004888;amide binding#GO:0033218 response to organic substance#GO:0010033;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to endogenous stimulus#GO:0009719;cellular response to hormone stimulus#GO:0032870;response to hormone#GO:0009725;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 CIOIN|Ensembl=ENSCING00000000308.3|UniProtKB=F6ZFY8 F6ZFY8 LOC100187540 PTHR11960:SF66 EUKARYOTIC TRANSLATION INITIATION FACTOR 4E RELATED EUKARYOTIC TRANSLATION INITIATION FACTOR 4E TYPE 3 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;translation regulator activity#GO:0045182;binding#GO:0005488;organic cyclic compound binding#GO:0097159;translation initiation factor activity#GO:0003743;RNA cap binding#GO:0000339;translation regulator activity, nucleic acid binding#GO:0090079;translation factor activity, RNA binding#GO:0008135 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;translational initiation#GO:0006413;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;intracellular protein-containing complex#GO:0140535;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622 translation initiation factor#PC00224;translation factor#PC00223;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000003215.3|UniProtKB=F6PM82 F6PM82 LOC100184110 PTHR23055:SF178 CALCIUM BINDING PROTEINS NEUROCALCIN HOMOLOG cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488 calmodulin-related#PC00061 CIOIN|Ensembl=ENSCING00000007771.3|UniProtKB=F6XT75 F6XT75 PTHR11254:SF340 HECT DOMAIN UBIQUITIN-PROTEIN LIGASE APOPTOSIS-RESISTANT E3 UBIQUITIN PROTEIN LIGASE 1 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 negative regulation of biological process#GO:0048519;macromolecule modification#GO:0043412;protein catabolic process#GO:0030163;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;post-translational protein modification#GO:0043687;regulation of biological process#GO:0050789;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;negative regulation of programmed cell death#GO:0043069;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein polyubiquitination#GO:0000209;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;negative regulation of cellular process#GO:0048523;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;regulation of programmed cell death#GO:0043067;metabolic process#GO:0008152;protein ubiquitination#GO:0016567;modification-dependent protein catabolic process#GO:0019941;macromolecule catabolic process#GO:0009057;protein modification by small protein conjugation or removal#GO:0070647;regulation of apoptotic process#GO:0042981;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;negative regulation of apoptotic process#GO:0043066;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;regulation of cellular process#GO:0050794;biological regulation#GO:0065007 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234 CIOIN|Ensembl=ENSCING00000003990.3|UniProtKB=F6WKJ4 F6WKJ4 PTHR28588:SF1 HAUS AUGMIN-LIKE COMPLEX SUBUNIT 5 HAUS AUGMIN-LIKE COMPLEX SUBUNIT 5 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cell cycle process#GO:0022402;centrosome cycle#GO:0007098;microtubule cytoskeleton organization#GO:0000226;cellular component organization#GO:0016043;cellular process#GO:0009987;microtubule organizing center organization#GO:0031023;chromosome segregation#GO:0007059;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;spindle assembly#GO:0051225;cell cycle#GO:0007049;cytoskeleton organization#GO:0007010;spindle organization#GO:0007051;non-membrane-bounded organelle assembly#GO:0140694 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule associated complex#GO:0005875;microtubule organizing center#GO:0005815;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;HAUS complex#GO:0070652;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000014481.2|UniProtKB=F6XM37 F6XM37 LOC100176811 PTHR12713:SF11 VACUOLAR ATP SYNTHASE SUBUNIT G V-TYPE PROTON ATPASE SUBUNIT G inorganic molecular entity transmembrane transporter activity#GO:0015318;catalytic activity#GO:0003824;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;ribonucleoside triphosphate phosphatase activity#GO:0017111;ATP hydrolysis activity#GO:0016887;ATPase-coupled transmembrane transporter activity#GO:0042626;monoatomic cation transmembrane transporter activity#GO:0008324;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;pyrophosphatase activity#GO:0016462;transmembrane transporter activity#GO:0022857;primary active transmembrane transporter activity#GO:0015399;ATP-dependent activity#GO:0140657;proton transmembrane transporter activity#GO:0015078;hydrolase activity#GO:0016787;active monoatomic ion transmembrane transporter activity#GO:0022853;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion transmembrane transporter activity#GO:0015075 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;vacuolar membrane#GO:0005774;ATPase complex#GO:1904949;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;proton-transporting two-sector ATPase complex#GO:0016469;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227 ATP synthase#PC00002;primary active transporter#PC00068;transporter#PC00227 CIOIN|Ensembl=ENSCING00000005885.3|UniProtKB=F6SII4 F6SII4 LOC100175804 PTHR31508:SF2 PROTEIN PITCHFORK PROTEIN PITCHFORK cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;binding#GO:0005488 biological regulation#GO:0065007;regulation of biological process#GO:0050789;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of cell projection organization#GO:0031344 CIOIN|Ensembl=ENSCING00000001010.3|UniProtKB=F6Y0J0 F6Y0J0 PTHR23043:SF26 HYPOXIA-INDUCIBLE FACTOR 1 ALPHA PROTEIN TRACHEALESS sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 basic helix-loop-helix transcription factor#PC00055 CIOIN|Ensembl=ENSCING00000002006.3|UniProtKB=F6WT81 F6WT81 LOC100181502 PTHR12264:SF21 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 12 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 12 protein binding#GO:0005515;nucleic acid binding#GO:0003676;transcription factor binding#GO:0008134;binding#GO:0005488;organic cyclic compound binding#GO:0097159;TBP-class protein binding#GO:0017025;DNA binding#GO:0003677 cellular aromatic compound metabolic process#GO:0006725;DNA-templated transcription#GO:0006351;cellular component biogenesis#GO:0044085;protein-DNA complex organization#GO:0071824;RNA metabolic process#GO:0016070;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;protein-DNA complex assembly#GO:0065004;nucleobase-containing compound metabolic process#GO:0006139;RNA polymerase II preinitiation complex assembly#GO:0051123;transcription initiation at RNA polymerase II promoter#GO:0006367;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;DNA-templated transcription initiation#GO:0006352;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular component assembly#GO:0022607;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;protein-containing complex organization#GO:0043933;aromatic compound biosynthetic process#GO:0019438;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;DNA-directed RNA polymerase complex#GO:0000428;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nucleoplasm#GO:0005654;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;transcription factor TFIID complex#GO:0005669;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622;RNA polymerase II, holoenzyme#GO:0016591;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;transcription regulator complex#GO:0005667;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 general transcription factor#PC00259 General transcription regulation#P00023>TBP-associated factors#P00658;Transcription regulation by bZIP transcription factor#P00055>TBP-associated factors#P01385 CIOIN|Ensembl=ENSCING00000021288.1|UniProtKB=H2XN28 H2XN28 PTHR19282:SF534 TETRASPANIN TETRASPANIN FAMILY-RELATED cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000024456.1|UniProtKB=H2Y3E7 H2Y3E7 LOC100178294 PTHR45629:SF7 SNF2/RAD54 FAMILY MEMBER DNA EXCISION REPAIR PROTEIN ERCC-6-RELATED damaged DNA-binding protein#PC00086;DNA metabolism protein#PC00009 CIOIN|Ensembl=ENSCING00000009904.3|UniProtKB=F6RAJ1 F6RAJ1 PTHR43969:SF9 GLUTATHIONE S TRANSFERASE D10, ISOFORM A-RELATED GLUTATHIONE S TRANSFERASE D10, ISOFORM A-RELATED glutathione transferase activity#GO:0004364;transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824 sulfur compound metabolic process#GO:0006790;nitrogen compound metabolic process#GO:0006807;peptide metabolic process#GO:0006518;cellular modified amino acid metabolic process#GO:0006575;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular process#GO:0009987;glutathione metabolic process#GO:0006749;amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000016539.2|UniProtKB=F6Y2B5 F6Y2B5 PTHR10361:SF19 SODIUM-BILE ACID COTRANSPORTER ILEAL SODIUM_BILE ACID COTRANSPORTER secondary active monocarboxylate transmembrane transporter activity#GO:0015355;inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;organic acid:sodium symporter activity#GO:0005343;organic acid transmembrane transporter activity#GO:0005342;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;bile acid transmembrane transporter activity#GO:0015125;organic anion transmembrane transporter activity#GO:0008514;monoatomic cation transmembrane transporter activity#GO:0008324;active transmembrane transporter activity#GO:0022804;lipid transporter activity#GO:0005319;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;metal ion transmembrane transporter activity#GO:0046873;active monoatomic ion transmembrane transporter activity#GO:0022853;monocarboxylic acid transmembrane transporter activity#GO:0008028;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294 localization#GO:0051179;organic hydroxy compound transport#GO:0015850;organic substance transport#GO:0071702;monocarboxylic acid transport#GO:0015718;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;organic anion transport#GO:0015711;organic acid transport#GO:0015849;transport#GO:0006810;carboxylic acid transport#GO:0046942;lipid localization#GO:0010876;bile acid and bile salt transport#GO:0015721;lipid transport#GO:0006869 primary active transporter#PC00068;transporter#PC00227 CIOIN|Ensembl=ENSCING00000003723.2|UniProtKB=F6WUK5 F6WUK5 LOC100185960 PTHR19300:SF61 BETA-1,4-GALACTOSYLTRANSFERASE BETA-1,4-N-ACETYLGALACTOSAMINYLTRANSFERASE galactosyltransferase activity#GO:0008378;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 glycosylation#GO:0070085;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000006046.3|UniProtKB=F6VSD0 F6VSD0 PTHR24092:SF190 PROBABLE PHOSPHOLIPID-TRANSPORTING ATPASE PHOSPHOLIPID-TRANSPORTING ATPASE ATPase-coupled intramembrane lipid transporter activity#GO:0140326;ATP-dependent activity#GO:0140657;transporter activity#GO:0005215;lipid transporter activity#GO:0005319 organophosphate ester transport#GO:0015748;Golgi organization#GO:0007030;macromolecule localization#GO:0033036;membrane organization#GO:0061024;transport#GO:0006810;endomembrane system organization#GO:0010256;cellular component organization#GO:0016043;regulation of membrane lipid distribution#GO:0097035;phospholipid transport#GO:0015914;cellular process#GO:0009987;lipid transport#GO:0006869;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;organelle organization#GO:0006996;biological regulation#GO:0065007;lipid translocation#GO:0034204;lipid localization#GO:0010876;phospholipid translocation#GO:0045332 cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;Golgi apparatus subcompartment#GO:0098791;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 primary active transporter#PC00068;transporter#PC00227 CIOIN|Ensembl=ENSCING00000021358.1|UniProtKB=H2Y1L6 H2Y1L6 PTHR19325:SF560 COMPLEMENT COMPONENT-RELATED SUSHI DOMAIN-CONTAINING SUSHI, VON WILLEBRAND FACTOR TYPE A, EGF AND PENTRAXIN DOMAIN-CONTAINING PROTEIN 1 complement component#PC00078 CIOIN|Ensembl=ENSCING00000007968.3|UniProtKB=F6Z7L3 F6Z7L3 PTHR19818:SF139 ZINC FINGER PROTEIN ZIC AND GLI PAIR-RULE PROTEIN ODD-PAIRED sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 CIOIN|Ensembl=ENSCING00000022701.1|UniProtKB=H2XNY7 H2XNY7 PTHR19432:SF34 SUGAR TRANSPORTER MEMBRANE-ASSOCIATED TRANSPORTER PROTEIN solute:proton symporter activity#GO:0015295;inorganic molecular entity transmembrane transporter activity#GO:0015318;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;proton transmembrane transporter activity#GO:0015078;carbohydrate transmembrane transporter activity#GO:0015144;active monoatomic ion transmembrane transporter activity#GO:0022853;symporter activity#GO:0015293;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;inorganic cation transmembrane transporter activity#GO:0022890;active transmembrane transporter activity#GO:0022804;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294 cellular anatomical entity#GO:0110165;membrane#GO:0016020 secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000006365.3|UniProtKB=F6RRX9 F6RRX9 PTHR14795:SF0 HELICASE RELATED TRANSMEMBRANE PROTEIN 62 RNA helicase#PC00032 CIOIN|Ensembl=ENSCING00000015783.2|UniProtKB=F6SJC3 F6SJC3 LOC100176472 PTHR23055:SF192 CALCIUM BINDING PROTEINS EF-HAND DOMAIN-CONTAINING PROTEIN cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488 calmodulin-related#PC00061 CIOIN|Ensembl=ENSCING00000003329.3|UniProtKB=F6S181 F6S181 LOC100183393 PTHR20856:SF5 DNA-DIRECTED RNA POLYMERASE I SUBUNIT 2 DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA2 catalytic activity, acting on RNA#GO:0140098;5'-3' RNA polymerase activity#GO:0034062;transferase activity#GO:0016740;DNA-directed 5'-3' RNA polymerase activity#GO:0003899;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;RNA polymerase activity#GO:0097747;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring phosphorus-containing groups#GO:0016772;RNA polymerase I activity#GO:0001054 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;DNA-directed RNA polymerase complex#GO:0000428;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular protein-containing complex#GO:0140535;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;RNA polymerase complex#GO:0030880;protein-containing complex#GO:0032991;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;RNA polymerase I complex#GO:0005736;nuclear protein-containing complex#GO:0140513 RNA metabolism protein#PC00031;DNA-directed RNA polymerase#PC00019 General transcription by RNA polymerase I#P00022>RNA Polymerase I Complex#P00652 CIOIN|Ensembl=ENSCING00000008613.3|UniProtKB=F6TNT4 F6TNT4 LOC100178604 PTHR22792:SF140 LUPUS LA PROTEIN-RELATED ACHILLES, ISOFORM A nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000003244.3|UniProtKB=F6Z5V2 F6Z5V2 PTHR47219:SF9 RAB GTPASE-ACTIVATING PROTEIN 1-LIKE GTPASE ACTIVATING PROTEIN AND CENTROSOME-ASSOCIATED, ISOFORM B nucleoside-triphosphatase regulator activity#GO:0060589;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;binding#GO:0005488;molecular function regulator activity#GO:0098772;enzyme binding#GO:0019899;protein binding#GO:0005515;enzyme activator activity#GO:0008047;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234 biological regulation#GO:0065007;regulation of hydrolase activity#GO:0051336;regulation of catalytic activity#GO:0050790;regulation of molecular function#GO:0065009;regulation of GTPase activity#GO:0043087 GTPase-activating protein#PC00257 CIOIN|Ensembl=ENSCING00000019064.1|UniProtKB=H2XW51 H2XW51 PTHR11850:SF329 HOMEOBOX PROTEIN TRANSCRIPTION FACTORS HOMEOBOX PROTEIN CUP9-RELATED DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 CIOIN|Ensembl=ENSCING00000003950.3|UniProtKB=F6Z370 F6Z370 PTHR45820:SF4 FI23527P1 ZINC TRANSPORTER 63C, ISOFORM F inorganic molecular entity transmembrane transporter activity#GO:0015318;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;inorganic cation transmembrane transporter activity#GO:0022890;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075 inorganic ion homeostasis#GO:0098771;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;homeostatic process#GO:0042592;inorganic ion transmembrane transport#GO:0098660;chemical homeostasis#GO:0048878;cellular process#GO:0009987;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;monoatomic ion homeostasis#GO:0050801;localization#GO:0051179;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation transport#GO:0006812;transition metal ion transport#GO:0000041;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655 cellular anatomical entity#GO:0110165;membrane#GO:0016020 CIOIN|Ensembl=ENSCING00000024758.1|UniProtKB=H2XNS3 H2XNS3 LOC100176180 PTHR24343:SF558 SERINE/THREONINE KINASE PROTEIN KINASE DOMAIN-CONTAINING PROTEIN transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;phosphorylation#GO:0016310;protein phosphorylation#GO:0006468;cellular process#GO:0009987;protein metabolic process#GO:0019538;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000007467.3|UniProtKB=F6YII5 F6YII5 PTHR24241:SF180 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;binding#GO:0005488;peptide binding#GO:0042277;transmembrane signaling receptor activity#GO:0004888;amide binding#GO:0033218 response to organic substance#GO:0010033;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to endogenous stimulus#GO:0009719;cellular response to hormone stimulus#GO:0032870;response to hormone#GO:0009725;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 CIOIN|Ensembl=ENSCING00000024473.1|UniProtKB=Q1RL70 Q1RL70 Ci-ZF(RING_RBZ)-1 PTHR22770:SF13 UBIQUITIN CONJUGATING ENZYME 7 INTERACTING PROTEIN-RELATED RING-TYPE DOMAIN-CONTAINING PROTEIN transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein binding#GO:0032182;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;ubiquitin binding#GO:0043130;protein binding#GO:0005515;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein polyubiquitination#GO:0000209;proteasomal protein catabolic process#GO:0010498;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;transferase complex#GO:1990234 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000000829.3|UniProtKB=F6R1L9 F6R1L9 LOC100181258 PTHR46464:SF1 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN ANKYRIN AND ARMADILLO REPEAT-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000024895.1|UniProtKB=A0A1W5BAW6 A0A1W5BAW6 LOC100186200 PTHR36978:SF4 P-LOOP CONTAINING NUCLEOTIDE TRIPHOSPHATE HYDROLASE P-LOOP CONTAINING NUCLEOSIDE TRIPHOSPHATE HYDROLASE PROTEIN metabolite interconversion enzyme#PC00262;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000000399.3|UniProtKB=F6WGS7 F6WGS7 PTHR10778:SF4 SOLUTE CARRIER FAMILY 35 MEMBER B NUCLEOTIDE SUGAR TRANSPORTER SLC35B4 carbohydrate derivative transmembrane transporter activity#GO:1901505;nucleobase-containing compound transmembrane transporter activity#GO:0015932;transmembrane transporter activity#GO:0022857;nucleotide-sugar transmembrane transporter activity#GO:0005338;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215 localization#GO:0051179;organic substance transport#GO:0071702;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;organic anion transport#GO:0015711;nucleobase-containing compound transport#GO:0015931;nucleotide-sugar transmembrane transport#GO:0015780;transport#GO:0006810;nitrogen compound transport#GO:0071705;cellular process#GO:0009987;carbohydrate derivative transport#GO:1901264 bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;Golgi membrane#GO:0000139;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000023451.1|UniProtKB=H2XMI0 H2XMI0 LOC100182060 PTHR15907:SF182 DUF614 FAMILY PROTEIN-RELATED PROTEIN PLANT CADMIUM RESISTANCE 1-RELATED CIOIN|Ensembl=ENSCING00000005966.3|UniProtKB=A0A8D3EQY1 A0A8D3EQY1 PTHR21266:SF32 IRON-SULFUR DOMAIN CONTAINING PROTEIN CHOLESTEROL 7-DESATURASE NVD oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 oxygenase#PC00177;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000022260.1|UniProtKB=H2XUW7 H2XUW7 LOC100183185 PTHR35666:SF1 SIMILAR TO RIKEN CDNA 4921536K21 SIMILAR TO RIKEN CDNA 4921536K21 CIOIN|Ensembl=ENSCING00000004223.3|UniProtKB=F6V620 F6V620 LOC100184836 PTHR10676:SF344 DYNEIN HEAVY CHAIN FAMILY PROTEIN DYNEIN AXONEMAL HEAVY CHAIN 5 cytoskeletal motor activity#GO:0003774;microtubule motor activity#GO:0003777;protein binding#GO:0005515;ATP-dependent activity#GO:0140657;binding#GO:0005488 cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;outer dynein arm assembly#GO:0036158;cell projection organization#GO:0030030;microtubule-based movement#GO:0007018;microtubule cytoskeleton organization#GO:0000226;cilium or flagellum-dependent cell motility#GO:0001539;protein-containing complex assembly#GO:0065003;cell motility#GO:0048870;cellular component organization#GO:0016043;axoneme assembly#GO:0035082;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031;cilium movement involved in cell motility#GO:0060294;cilium movement#GO:0003341;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cilium-dependent cell motility#GO:0060285;microtubule-based process#GO:0007017;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;microtubule bundle formation#GO:0001578;axonemal dynein complex assembly#GO:0070286;cytoskeleton organization#GO:0007010;plasma membrane bounded cell projection assembly#GO:0120031 axoneme#GO:0005930;outer dynein arm#GO:0036157;catalytic complex#GO:1902494;cytoplasmic region#GO:0099568;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;microtubule associated complex#GO:0005875;axonemal dynein complex#GO:0005858;non-membrane-bounded organelle#GO:0043228;motile cilium#GO:0031514;protein-containing complex#GO:0032991;9+2 motile cilium#GO:0097729;microtubule cytoskeleton#GO:0015630;ciliary plasm#GO:0097014;plasma membrane bounded cell projection cytoplasm#GO:0032838;membrane-bounded organelle#GO:0043227;dynein complex#GO:0030286;cell projection#GO:0042995;cytoskeleton#GO:0005856;cilium#GO:0005929 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 Huntington disease#P00029>Dynein complex#P00774 CIOIN|Ensembl=ENSCING00000002292.3|UniProtKB=F6PST3 F6PST3 LOC100175820 PTHR10113:SF10 PEPTIDE CHAIN RELEASE FACTOR SUBUNIT 1 EUKARYOTIC PEPTIDE CHAIN RELEASE FACTOR SUBUNIT 1 translation release factor#PC00225;translation factor#PC00223;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000008941.3|UniProtKB=F6Q6Q9 F6Q6Q9 LOC100175966 PTHR45652:SF21 GLIAL FIBRILLARY ACIDIC PROTEIN ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 13-LIKE ISOFORM X1 structural molecule activity#GO:0005198;structural constituent of cytoskeleton#GO:0005200 cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;intermediate filament organization#GO:0045109;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cellular process#GO:0009987;intermediate filament cytoskeleton organization#GO:0045104;intermediate filament-based process#GO:0045103 supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intermediate filament#GO:0005882;intermediate filament cytoskeleton#GO:0045111;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;supramolecular fiber#GO:0099512;supramolecular polymer#GO:0099081;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 intermediate filament#PC00129 CIOIN|Ensembl=ENSCING00000023124.1|UniProtKB=H2XT83 H2XT83 PTHR23507:SF2 ZGC:174356 PROTON-COUPLED FOLATE TRANSPORTER transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 localization#GO:0051179;establishment of localization#GO:0051234;cellular process#GO:0009987;transmembrane transport#GO:0055085;transport#GO:0006810 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 CIOIN|Ensembl=ENSCING00000011907.2|UniProtKB=F6WS20 F6WS20 PTHR24240:SF223 OPSIN MELATONIN RECEPTOR 1B signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 signal transduction#GO:0007165;response to light stimulus#GO:0009416;cellular response to stimulus#GO:0051716;detection of stimulus#GO:0051606;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;regulation of cellular process#GO:0050794;response to radiation#GO:0009314;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;response to abiotic stimulus#GO:0009628;signaling#GO:0023052;cellular response to light stimulus#GO:0071482 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 CIOIN|Ensembl=ENSCING00000002572.3|UniProtKB=F6UET6 F6UET6 PTHR11063:SF8 GLUTAMATE SEMIALDEHYDE DEHYDROGENASE DELTA-1-PYRROLINE-5-CARBOXYLATE SYNTHASE oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 dehydrogenase#PC00092;oxidoreductase#PC00176 Proline biosynthesis#P02768>Glutamate semialdehyde dehydrogenase#P03112 CIOIN|Ensembl=ENSCING00000012671.2|UniProtKB=A0A1W5B7I0 A0A1W5B7I0 LOC100179844 PTHR46582:SF1 ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 18 ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 18 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;precatalytic spliceosome#GO:0071011;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000018146.1|UniProtKB=H2XUJ1 H2XUJ1 PTHR22906:SF46 PROPERDIN HEMICENTIN-1-LIKE CIOIN|Ensembl=ENSCING00000022370.1|UniProtKB=H2XX84 H2XX84 PTHR24240:SF223 OPSIN MELATONIN RECEPTOR 1B signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 signal transduction#GO:0007165;response to light stimulus#GO:0009416;cellular response to stimulus#GO:0051716;detection of stimulus#GO:0051606;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;regulation of cellular process#GO:0050794;response to radiation#GO:0009314;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;response to abiotic stimulus#GO:0009628;signaling#GO:0023052;cellular response to light stimulus#GO:0071482 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 CIOIN|Ensembl=ENSCING00000014649.2|UniProtKB=F7BI48 F7BI48 LOC100177160 PTHR31905:SF2 COILED-COIL DOMAIN-CONTAINING PROTEIN 58 PROTEIN MIX23 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000007265.3|UniProtKB=F6THX7 F6THX7 PTHR12084:SF0 NUCLEAR PORE GLYCOPROTEIN P62-RELATED NUCLEAR PORE GLYCOPROTEIN P62 lipid binding#GO:0008289;structural molecule activity#GO:0005198;phospholipid binding#GO:0005543;structural constituent of nuclear pore#GO:0017056;binding#GO:0005488 cellular localization#GO:0051641;macromolecule localization#GO:0033036;establishment of RNA localization#GO:0051236;transport#GO:0006810;protein localization to nucleus#GO:0034504;nucleic acid transport#GO:0050657;nitrogen compound transport#GO:0071705;establishment of protein localization to organelle#GO:0072594;cellular process#GO:0009987;establishment of protein localization#GO:0045184;RNA localization#GO:0006403;protein localization#GO:0008104;localization#GO:0051179;organic substance transport#GO:0071702;protein import into nucleus#GO:0006606;cellular macromolecule localization#GO:0070727;nuclear export#GO:0051168;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;RNA transport#GO:0050658;nucleobase-containing compound transport#GO:0015931;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;protein localization to organelle#GO:0033365;RNA export from nucleus#GO:0006405;nuclear transport#GO:0051169;import into nucleus#GO:0051170 envelope#GO:0031975;nuclear pore#GO:0005643;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear envelope#GO:0005635;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;organelle envelope#GO:0031967;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transporter#PC00227 CIOIN|Ensembl=ENSCING00000013961.2|UniProtKB=F6RN78 F6RN78 LOC100186965 PTHR24068:SF116 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN CONJUGATING ENZYME E2 L3 ubiquitin-like protein conjugating enzyme activity#GO:0061650;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;ubiquitin-like protein ligase binding#GO:0044389;enzyme binding#GO:0019899;ubiquitin conjugating enzyme activity#GO:0061631;protein binding#GO:0005515;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin protein ligase binding#GO:0031625 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;protein polyubiquitination#GO:0000209;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 Parkinson disease#P00049>UbcH7#P01224;Parkinson disease#P00049>UbcH8#P01223;Ubiquitin proteasome pathway#P00060>E2#P01491 CIOIN|Ensembl=ENSCING00000022651.1|UniProtKB=H2XRN7 H2XRN7 PTHR20995:SF17 F-BOX/WD REPEAT-CONTAINING PROTEIN 5 F-BOX_WD REPEAT-CONTAINING PROTEIN 5 CIOIN|Ensembl=ENSCING00000002543.3|UniProtKB=F6XQV0 F6XQV0 PTHR13024:SF0 MICROSOMAL TRIGLYCERIDE TRANSFER PROTEIN, LARGE SUBUNIT MICROSOMAL TRIACYLGLYCEROL TRANSFER PROTEIN phospholipid transporter activity#GO:0005548;transporter activity#GO:0005215;lipid transporter activity#GO:0005319 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;lipoprotein metabolic process#GO:0042157;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 intracellular membrane-bounded organelle#GO:0043231;basolateral plasma membrane#GO:0016323;Golgi apparatus#GO:0005794;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;basal plasma membrane#GO:0009925;endomembrane system#GO:0012505;plasma membrane region#GO:0098590;membrane-bounded organelle#GO:0043227;basal part of cell#GO:0045178;endoplasmic reticulum#GO:0005783;plasma membrane#GO:0005886 transporter#PC00227 CIOIN|Ensembl=ENSCING00000003618.3|UniProtKB=F6U899 F6U899 PTHR48094:SF12 PROTEIN/NUCLEIC ACID DEGLYCASE DJ-1-RELATED PARKINSON DISEASE PROTEIN 7 HOMOLOG cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000023935.1|UniProtKB=H2Y0S1 H2Y0S1 PTHR15441:SF1 RIBONUCLEASE P PROTEIN SUBUNIT P14 RIBONUCLEASE P PROTEIN SUBUNIT P14 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;endoribonuclease complex#GO:1902555;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;endonuclease complex#GO:1905348;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;ribonuclease P complex#GO:0030677;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 endoribonuclease#PC00094;RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000007718.3|UniProtKB=H2XP00 H2XP00 PTHR12517:SF0 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 13B INTERMEMBRANE LIPID TRANSFER PROTEIN VPS13B membrane traffic protein#PC00150 CIOIN|Ensembl=ENSCING00000020016.1|UniProtKB=H2Y369 H2Y369 PTHR10283:SF82 SOLUTE CARRIER FAMILY 13 MEMBER SOLUTE CARRIER FAMILY 13 MEMBER 2 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 localization#GO:0051179;establishment of localization#GO:0051234;cellular process#GO:0009987;transmembrane transport#GO:0055085;transport#GO:0006810 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000005377.3|UniProtKB=F7AC23 F7AC23 PTHR11552:SF147 GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE CHOLINE DEHYDROGENASE, MITOCHONDRIAL oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000003043.3|UniProtKB=F6Q6F5 F6Q6F5 LOC100182404 PTHR25464:SF2 TRIPARTITE MOTIF-CONTAINING PROTEIN 2-LIKE PROTEIN RING-TYPE DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000021021.1|UniProtKB=H2Y3M9 H2Y3M9 PTHR24096:SF149 LONG-CHAIN-FATTY-ACID--COA LIGASE AMP-BINDING DOMAIN-CONTAINING PROTEIN-RELATED ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877 metabolite interconversion enzyme#PC00262;ligase#PC00142 CIOIN|Ensembl=ENSCING00000011997.2|UniProtKB=F6RID7 F6RID7 LOC100183090 PTHR21139:SF2 TRIOSEPHOSPHATE ISOMERASE TRIOSEPHOSPHATE ISOMERASE isomerase activity#GO:0016853;catalytic activity#GO:0003824 ribonucleoside triphosphate metabolic process#GO:0009199;nucleoside triphosphate metabolic process#GO:0009141;heterocycle catabolic process#GO:0046700;ribonucleotide catabolic process#GO:0009261;pyridine nucleotide metabolic process#GO:0019362;nucleobase-containing compound metabolic process#GO:0006139;ATP metabolic process#GO:0046034;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;purine ribonucleotide catabolic process#GO:0009154;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;pyridine-containing compound metabolic process#GO:0072524;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;organic hydroxy compound metabolic process#GO:1901615;oxoacid metabolic process#GO:0043436;nucleoside phosphate catabolic process#GO:1901292;carbohydrate derivative catabolic process#GO:1901136;purine ribonucleoside triphosphate metabolic process#GO:0009205;generation of precursor metabolites and energy#GO:0006091;cellular metabolic process#GO:0044237;nucleotide catabolic process#GO:0009166;alcohol metabolic process#GO:0006066;cellular nitrogen compound metabolic process#GO:0034641;nicotinamide nucleotide metabolic process#GO:0046496;nucleoside diphosphate catabolic process#GO:0009134;organic acid metabolic process#GO:0006082;ribonucleotide metabolic process#GO:0009259;monocarboxylic acid metabolic process#GO:0032787;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;organophosphate catabolic process#GO:0046434;carbohydrate derivative biosynthetic process#GO:1901137;hexose biosynthetic process#GO:0019319;small molecule catabolic process#GO:0044282;glycolytic process#GO:0006096;organophosphate metabolic process#GO:0019637;small molecule biosynthetic process#GO:0044283;nucleobase-containing compound catabolic process#GO:0034655;nucleotide metabolic process#GO:0009117;small molecule metabolic process#GO:0044281;cellular aromatic compound metabolic process#GO:0006725;monosaccharide metabolic process#GO:0005996;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;organonitrogen compound catabolic process#GO:1901565;biosynthetic process#GO:0009058;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;purine-containing compound catabolic process#GO:0072523;cellular nitrogen compound catabolic process#GO:0044270;purine nucleotide catabolic process#GO:0006195;organic cyclic compound metabolic process#GO:1901360;carbohydrate catabolic process#GO:0016052;catabolic process#GO:0009056;nucleoside diphosphate metabolic process#GO:0009132;organic substance catabolic process#GO:1901575;carbohydrate metabolic process#GO:0005975;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;carbohydrate biosynthetic process#GO:0016051;heterocycle metabolic process#GO:0046483;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;glucose metabolic process#GO:0006006;aromatic compound catabolic process#GO:0019439;organic cyclic compound catabolic process#GO:1901361;purine nucleoside triphosphate metabolic process#GO:0009144;hexose metabolic process#GO:0019318;carboxylic acid metabolic process#GO:0019752;nucleobase-containing small molecule metabolic process#GO:0055086 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 isomerase#PC00135;metabolite interconversion enzyme#PC00262 Glycolysis#P00024>Triosephosphate isomerase#P00673 CIOIN|Ensembl=ENSCING00000023055.1|UniProtKB=H2XP87 H2XP87 PTHR21580:SF57 SHIPPO-1-RELATED OUTER DENSE FIBER OF SPERM TAILS 3-LIKE 2-RELATED intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 structural protein#PC00211 CIOIN|Ensembl=ENSCING00000004152.3|UniProtKB=A0A1W5B998 A0A1W5B998 zf(c2h2)-27 PTHR24377:SF995 IP01015P-RELATED FI01202P sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 CIOIN|Ensembl=ENSCING00000011474.2|UniProtKB=F6XIG6 F6XIG6 PTHR21297:SF0 DNA-DIRECTED RNA POLYMERASE II DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB4 protein binding#GO:0005515;translation initiation factor binding#GO:0031369;binding#GO:0005488 cellular aromatic compound metabolic process#GO:0006725;DNA-templated transcription#GO:0006351;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;RNA processing#GO:0006396;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;transcription initiation at RNA polymerase II promoter#GO:0006367;mRNA 3'-end processing#GO:0031124;protein-RNA complex assembly#GO:0022618;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;DNA-templated transcription initiation#GO:0006352;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular component assembly#GO:0022607;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cellular component organization#GO:0016043;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;protein-containing complex organization#GO:0043933;ribonucleoprotein complex biogenesis#GO:0022613;mRNA processing#GO:0006397;aromatic compound biosynthetic process#GO:0019438;protein-RNA complex organization#GO:0071826;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;RNA polymerase II, core complex#GO:0005665;organelle lumen#GO:0043233;nucleus#GO:0005634;DNA-directed RNA polymerase complex#GO:0000428;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nucleoplasm#GO:0005654;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622;RNA polymerase II, holoenzyme#GO:0016591;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 RNA metabolism protein#PC00031;DNA-directed RNA polymerase#PC00019 Transcription regulation by bZIP transcription factor#P00055>RNA Polymerase II#P01388;General transcription regulation#P00023>RNA Polymerase II#P00660 CIOIN|Ensembl=ENSCING00000007892.3|UniProtKB=F6SUA6 F6SUA6 PTHR11482:SF6 ARGININE/DIAMINOPIMELATE/ORNITHINE DECARBOXYLASE ORNITHINE DECARBOXYLASE 1-RELATED lyase activity#GO:0016829;carboxy-lyase activity#GO:0016831;carbon-carbon lyase activity#GO:0016830;catalytic activity#GO:0003824 amine metabolic process#GO:0009308;oxoacid metabolic process#GO:0043436;biogenic amine metabolic process#GO:0006576;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;polyamine metabolic process#GO:0006595;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;alpha-amino acid metabolic process#GO:1901605;polyamine biosynthetic process#GO:0006596;carboxylic acid metabolic process#GO:0019752;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 decarboxylase#PC00089 Ornithine degradation#P02758>Ornithine decarboxylase#P03053 CIOIN|Ensembl=ENSCING00000004771.3|UniProtKB=F6ZGX7 F6ZGX7 PTHR11164:SF0 GLUTAMATE CYSTEINE LIGASE GLUTAMATE--CYSTEINE LIGASE CATALYTIC SUBUNIT ligase activity#GO:0016874;catalytic activity#GO:0003824 sulfur compound metabolic process#GO:0006790;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;glutathione metabolic process#GO:0006749;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;cellular modified amino acid metabolic process#GO:0006575;amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 ligase#PC00142;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000006852.3|UniProtKB=F6UH52 F6UH52 PTHR11929:SF145 ALPHA- 1,3 -FUCOSYLTRANSFERASE ALPHA-(1,3)-FUCOSYLTRANSFERASE FUT-1 transferase activity#GO:0016740;fucosyltransferase activity#GO:0008417;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 glycosylation#GO:0070085;metabolic process#GO:0008152 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000013691.2|UniProtKB=F6PSG3 F6PSG3 LOC100175829 PTHR31581:SF1 KICSTOR COMPLEX PROTEIN C12ORF66 KICSTOR SUBUNIT 2 cellular localization#GO:0051641;negative regulation of biological process#GO:0048519;macromolecule localization#GO:0033036;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;response to extracellular stimulus#GO:0009991;regulation of intracellular signal transduction#GO:1902531;negative regulation of TOR signaling#GO:0032007;regulation of biological process#GO:0050789;cellular response to starvation#GO:0009267;regulation of signal transduction#GO:0009966;protein localization to organelle#GO:0033365;negative regulation of cell communication#GO:0010648;negative regulation of cellular process#GO:0048523;cellular response to extracellular stimulus#GO:0031668;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of TORC1 signaling#GO:1903432;negative regulation of response to stimulus#GO:0048585;protein localization to vacuole#GO:0072665;negative regulation of signaling#GO:0023057;cell communication#GO:0007154;response to nutrient levels#GO:0031667;cellular process#GO:0009987;regulation of TOR signaling#GO:0032006;protein localization#GO:0008104;localization#GO:0051179;regulation of response to stimulus#GO:0048583;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;protein localization to lysosome#GO:0061462;cellular macromolecule localization#GO:0070727;response to stress#GO:0006950;cellular response to nutrient levels#GO:0031669;regulation of cellular process#GO:0050794;response to starvation#GO:0042594;biological regulation#GO:0065007;cellular response to external stimulus#GO:0071496;negative regulation of signal transduction#GO:0009968;cellular response to amino acid starvation#GO:0034198;cellular response to stress#GO:0033554;negative regulation of TORC1 signaling#GO:1904262 protein-containing complex#GO:0032991 CIOIN|Ensembl=ENSCING00000001006.3|UniProtKB=F6Y146 F6Y146 PTHR13954:SF6 IRE1-RELATED NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE tyrosine protein kinase receptor#PC00233 Alzheimer disease-presenilin pathway#P00004>Ire-1#P00144;Alzheimer disease-presenilin pathway#P00004>Ire-1 N-terminal fragment#P00110;Alzheimer disease-presenilin pathway#P00004>Ire-1 C-terminal fragment#P00125 CIOIN|Ensembl=ENSCING00000001730.3|UniProtKB=F6T8Y3 F6T8Y3 PTHR11562:SF17 CATION EFFLUX PROTEIN/ ZINC TRANSPORTER RE54080P-RELATED inorganic molecular entity transmembrane transporter activity#GO:0015318;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;inorganic cation transmembrane transporter activity#GO:0022890;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075 localization#GO:0051179;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;monoatomic cation transport#GO:0006812;transition metal ion transport#GO:0000041;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transporter#PC00227 CIOIN|Ensembl=ENSCING00000021318.1|UniProtKB=H2XUF7 H2XUF7 PTHR12932:SF9 P25 ALPHA-RELATED TUBULIN POLYMERIZATION-PROMOTING PROTEIN HOMOLOG cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;microtubule cytoskeleton organization#GO:0000226;protein-containing complex assembly#GO:0065003;regulation of cellular component organization#GO:0051128;cellular component organization#GO:0016043;cellular process#GO:0009987;microtubule polymerization or depolymerization#GO:0031109;positive regulation of protein polymerization#GO:0032273;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of protein-containing complex assembly#GO:0043254;microtubule polymerization#GO:0046785;microtubule-based process#GO:0007017;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;regulation of cellular component biogenesis#GO:0044087;protein-containing complex organization#GO:0043933;supramolecular fiber organization#GO:0097435;microtubule bundle formation#GO:0001578;biological regulation#GO:0065007;protein polymerization#GO:0051258;positive regulation of cellular component organization#GO:0051130;cytoskeleton organization#GO:0007010;positive regulation of cellular component biogenesis#GO:0044089;regulation of protein polymerization#GO:0032271;positive regulation of biological process#GO:0048518 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 CIOIN|Ensembl=ENSCING00000002739.3|UniProtKB=F6T2S3 F6T2S3 LOC100184392 PTHR12072:SF4 CWF19, CELL CYCLE CONTROL PROTEIN CWF19-LIKE PROTEIN 1 enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;post-mRNA release spliceosomal complex#GO:0071014;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000019816.1|UniProtKB=H2XMY6 H2XMY6 PTHR11848:SF263 TGF-BETA FAMILY PROTEIN DECAPENTAPLEGIC molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;cytokine activity#GO:0005125;protein binding#GO:0005515;signaling receptor binding#GO:0005102 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 DPP signaling pathway#P06213>DPP#P06285;BMP/activin signaling pathway-drosophila#P06211>Full-length BMP orthologous ligand#P06256;DPP signaling pathway#P06213>DPP full length#P06282;TGF-beta signaling pathway#P00052>TGFbeta#P01286;DPP-SCW signaling pathway#P06212>DPP full length#P06273;DPP-SCW signaling pathway#P06212>DPP#P06272;BMP/activin signaling pathway-drosophila#P06211>BMP/activin orthologous ligand#P06251 CIOIN|Ensembl=ENSCING00000015660.2|UniProtKB=F6X555 F6X555 LOC100178899 PTHR13382:SF77 MITOCHONDRIAL ATP SYNTHASE COUPLING FACTOR B REPEAT PROTEIN (LRRP), PUTATIVE-RELATED cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ATP synthase#PC00002;primary active transporter#PC00068;transporter#PC00227 CIOIN|Ensembl=ENSCING00000007177.3|UniProtKB=F6ZAQ4 F6ZAQ4 PTHR10574:SF435 NETRIN/LAMININ-RELATED LAMININ SUBUNIT GAMMA-1 neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;cell projection organization#GO:0030030;animal organ development#GO:0048513;developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cellular anatomical entity morphogenesis#GO:0032989;system development#GO:0048731;cell differentiation#GO:0030154;axon guidance#GO:0007411;anatomical structure morphogenesis#GO:0009653;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;axonogenesis#GO:0007409;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;cellular component organization#GO:0016043;cell morphogenesis#GO:0000902;cellular process#GO:0009987;tissue development#GO:0009888;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;cell morphogenesis involved in neuron differentiation#GO:0048667;anatomical structure development#GO:0048856;animal organ morphogenesis#GO:0009887;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699 extracellular matrix protein#PC00102 Integrin signalling pathway#P00034>Laminin#P00947 CIOIN|Ensembl=ENSCING00000002435.3|UniProtKB=F6RKZ8 F6RKZ8 PTHR12649:SF11 PEPTIDYL-TRNA HYDROLASE 2 PEPTIDYL-TRNA HYDROLASE 2, MITOCHONDRIAL CIOIN|Ensembl=ENSCING00000007311.3|UniProtKB=F7AG13 F7AG13 LOC104266424 PTHR43569:SF2 AMIDOHYDROLASE AMIDOHYDROLASE-RELATED DOMAIN-CONTAINING PROTEIN metabolite interconversion enzyme#PC00262;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000013345.2|UniProtKB=F6SXL4 F6SXL4 LOC100186518 PTHR24390:SF244 ZINC FINGER PROTEIN LD33778P-RELATED sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 CIOIN|Ensembl=ENSCING00000001874.3|UniProtKB=F6SJY8 F6SJY8 LOC100187427 PTHR12736:SF7 LANC-LIKE PROTEIN LANC-LIKE PROTEIN 3 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 CIOIN|Ensembl=ENSCING00000006728.3|UniProtKB=F6YLK0 F6YLK0 PTHR19300:SF61 BETA-1,4-GALACTOSYLTRANSFERASE BETA-1,4-N-ACETYLGALACTOSAMINYLTRANSFERASE galactosyltransferase activity#GO:0008378;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 glycosylation#GO:0070085;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000008639.3|UniProtKB=F7AGW4 F7AGW4 PTHR10527:SF6 IMPORTIN BETA IMPORTIN-4 signal sequence binding#GO:0005048;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277 cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;protein localization to nucleus#GO:0034504;nitrogen compound transport#GO:0071705;establishment of protein localization to organelle#GO:0072594;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;protein import into nucleus#GO:0006606;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;protein localization to organelle#GO:0033365;intracellular transport#GO:0046907;nuclear transport#GO:0051169;import into nucleus#GO:0051170 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transporter#PC00227 CIOIN|Ensembl=ENSCING00000005643.3|UniProtKB=F6ZQX9 F6ZQX9 LOC100182402 PTHR10052:SF1 60S RIBOSOMAL PROTEIN L18A LARGE RIBOSOMAL SUBUNIT PROTEIN EL20 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic large ribosomal subunit#GO:0022625;large ribosomal subunit#GO:0015934;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000024156.1|UniProtKB=F6XW35 F6XW35 LOC100178900 PTHR20835:SF0 E3 UBIQUITIN-PROTEIN LIGASE PPP1R11-RELATED E3 UBIQUITIN-PROTEIN LIGASE PPP1R11 phosphatase binding#GO:0019902;phosphatase regulator activity#GO:0019208;binding#GO:0005488;molecular function regulator activity#GO:0098772;protein phosphatase regulator activity#GO:0019888;enzyme binding#GO:0019899;protein binding#GO:0005515;phosphatase inhibitor activity#GO:0019212;enzyme inhibitor activity#GO:0004857;protein phosphatase binding#GO:0019903;molecular function inhibitor activity#GO:0140678;protein phosphatase inhibitor activity#GO:0004864;enzyme regulator activity#GO:0030234;protein serine/threonine phosphatase inhibitor activity#GO:0004865 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000019214.1|UniProtKB=F6T435 F6T435 LOC100186547 PTHR11929:SF145 ALPHA- 1,3 -FUCOSYLTRANSFERASE ALPHA-(1,3)-FUCOSYLTRANSFERASE FUT-1 transferase activity#GO:0016740;fucosyltransferase activity#GO:0008417;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 glycosylation#GO:0070085;metabolic process#GO:0008152 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000018153.1|UniProtKB=H2XRD7 H2XRD7 PTHR19325:SF567 COMPLEMENT COMPONENT-RELATED SUSHI DOMAIN-CONTAINING SUSHI, VON WILLEBRAND FACTOR TYPE A, EGF AND PENTRAXIN DOMAIN-CONTAINING PROTEIN 1-LIKE complement component#PC00078 CIOIN|Ensembl=ENSCING00000007079.3|UniProtKB=F6W9I8 F6W9I8 PTHR45709:SF2 LARGE SUBUNIT GTPASE 1 HOMOLOG-RELATED LARGE SUBUNIT GTPASE 1 HOMOLOG hydrolase activity#GO:0016787;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000000895.3|UniProtKB=F7BC45 F7BC45 PTHR24099:SF5 E3 UBIQUITIN-PROTEIN LIGASE TRIM36-RELATED FSD1-LIKE PROTEIN ubiquitin-protein ligase#PC00234 CIOIN|Ensembl=ENSCING00000008844.3|UniProtKB=F6R4F4 F6R4F4 PTHR11875:SF7 TESTIS-SPECIFIC Y-ENCODED PROTEIN AT14585P-RELATED protein binding#GO:0005515;protein-containing complex binding#GO:0044877;histone binding#GO:0042393;binding#GO:0005488;chromatin binding#GO:0003682 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;protein-DNA complex organization#GO:0071824;nucleosome organization#GO:0034728;nucleosome assembly#GO:0006334;protein-containing complex organization#GO:0043933;protein-containing complex assembly#GO:0065003;chromatin organization#GO:0006325;cellular component organization#GO:0016043;protein-DNA complex assembly#GO:0065004;chromatin remodeling#GO:0006338;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 CIOIN|Ensembl=ENSCING00000017979.1|UniProtKB=H2XRA0 H2XRA0 PTHR12586:SF1 CDP-DIACYLGLYCEROL--SERINE O-PHOSPHATIDYLTRANSFERASE CDP-DIACYLGLYCEROL--GLYCEROL-3-PHOSPHATE 3-PHOSPHATIDYLTRANSFERASE, MITOCHONDRIAL transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000012409.2|UniProtKB=F6YPV8 F6YPV8 PTHR43539:SF23 FLAVIN-BINDING MONOOXYGENASE-LIKE PROTEIN (AFU_ORTHOLOGUE AFUA_4G09220) FAD-DEPENDENT OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN 2 nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;flavin adenine dinucleotide binding#GO:0050660;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;anion binding#GO:0043168;oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497 response to organic substance#GO:0010033;macromolecule catabolic process#GO:0009057;cellular response to stimulus#GO:0051716;response to endoplasmic reticulum stress#GO:0034976;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;response to organonitrogen compound#GO:0010243;ERAD pathway#GO:0036503;cellular process#GO:0009987;primary metabolic process#GO:0044238;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;cellular response to stress#GO:0033554;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;endoplasmic reticulum lumen#GO:0005788;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 oxygenase#PC00177;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000001279.3|UniProtKB=F6ZVE1 F6ZVE1 PTHR11709:SF518 MULTI-COPPER OXIDASE MULTICOPPER OXIDASE oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 oxidase#PC00175;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000002176.3|UniProtKB=F6SSF8 F6SSF8 PTHR11467:SF36 HISTONE H1 HISTONE 24-RELATED nucleosome binding#GO:0031491;nucleic acid binding#GO:0003676;chromatin DNA binding#GO:0031490;binding#GO:0005488;organic cyclic compound binding#GO:0097159;chromatin binding#GO:0003682;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;protein-containing complex binding#GO:0044877 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA metabolic process#GO:0051052;chromosome condensation#GO:0030261;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;cellular process#GO:0009987;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA recombination#GO:0045910;negative regulation of DNA metabolic process#GO:0051053;regulation of DNA recombination#GO:0000018;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 CIOIN|Ensembl=ENSCING00000009389.3|UniProtKB=H2XR49 H2XR49 PTHR45984:SF1 RNA (RNA) POLYMERASE II ASSOCIATED PROTEIN HOMOLOG SPAG1 AXONEMAL DYNEIN ASSEMBLY FACTOR protein binding#GO:0005515;heat shock protein binding#GO:0031072;binding#GO:0005488 localization#GO:0051179;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;protein targeting to mitochondrion#GO:0006626;establishment of localization#GO:0051234;establishment of protein localization to mitochondrion#GO:0072655;protein targeting#GO:0006605;establishment of protein localization to organelle#GO:0072594;protein localization to organelle#GO:0033365;cellular process#GO:0009987;protein localization to mitochondrion#GO:0070585;establishment of protein localization#GO:0045184;protein localization#GO:0008104 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000004846.3|UniProtKB=F6TYN3 F6TYN3 LOC100182217 PTHR11711:SF455 ADP RIBOSYLATION FACTOR-RELATED ADP-RIBOSYLATION FACTOR 2 carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167 cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 G-protein#PC00020 Huntington disease#P00029>ARF#P00786 CIOIN|Ensembl=ENSCING00000016362.2|UniProtKB=F6VGQ2 F6VGQ2 PTHR24039:SF58 FIBRILLIN-RELATED EGF-LIKE DOMAIN-CONTAINING PROTEIN extracellular matrix structural protein#PC00103 CIOIN|Ensembl=ENSCING00000019549.1|UniProtKB=H2Y0Z1 H2Y0Z1 PTHR19871:SF14 BETA TRANSDUCIN-RELATED PROTEIN DUF4062 DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000009404.3|UniProtKB=F6U9N4 F6U9N4 PTHR14454:SF12 GRB2-ASSOCIATED AND REGULATOR OF MAPK PROTEIN FAMILY MEMBER GRB2-ASSOCIATED AND REGULATOR OF MAPK PROTEIN 2-LIKE CIOIN|Ensembl=ENSCING00000000255.3|UniProtKB=Q1RQ07 Q1RQ07 Ci-ZF(C2H2)-57 PTHR46698:SF4 CROSSVEINLESS 2 CROSSVEINLESS 2 cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 CIOIN|Ensembl=ENSCING00000001847.3|UniProtKB=F6T7H6 F6T7H6 PTHR10695:SF46 DEPHOSPHO-COA KINASE-RELATED BIFUNCTIONAL COENZYME A SYNTHASE-RELATED transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301 cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 kinase#PC00137 Coenzyme A biosynthesis#P02736>Pantetheine-phosphate adenyltransferase#P02886;Coenzyme A biosynthesis#P02736>Dephospho-CoA kinase#P02884 CIOIN|Ensembl=ENSCING00000022766.1|UniProtKB=H2XMM7 H2XMM7 PTHR31025:SF25 SI:CH211-196P9.1-RELATED ZINC FINGER (C2H2)-60 CIOIN|Ensembl=ENSCING00000008138.3|UniProtKB=F6UIG7 F6UIG7 PTHR11006:SF10 PROTEIN ARGININE N-METHYLTRANSFERASE HISTONE-ARGININE METHYLTRANSFERASE CARMER-RELATED N-methyltransferase activity#GO:0008170;histone modifying activity#GO:0140993;transferase activity#GO:0016740;catalytic activity#GO:0003824;histone methyltransferase activity#GO:0042054;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a protein#GO:0140096;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;protein methyltransferase activity#GO:0008276 protein-DNA complex organization#GO:0071824;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular component organization#GO:0016043;peptidyl-amino acid modification#GO:0018193;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;methylation#GO:0032259;macromolecule methylation#GO:0043414;nitrogen compound metabolic process#GO:0006807;protein-containing complex organization#GO:0043933;chromatin organization#GO:0006325;chromatin remodeling#GO:0006338;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000001795.2|UniProtKB=F6X5Z3 F6X5Z3 LOC100181572 PTHR24214:SF38 PDZ AND LIM DOMAIN PROTEIN ZASP PDZ AND LIM DOMAIN PROTEIN ZASP-RELATED cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 CIOIN|Ensembl=ENSCING00000012240.2|UniProtKB=F7B5G8 F7B5G8 LOC100181701 PTHR12794:SF0 GEMIN2 GEM-ASSOCIATED PROTEIN 2 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;RNA processing#GO:0006396;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;protein-RNA complex assembly#GO:0022618;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;spliceosomal snRNP assembly#GO:0000387;organic substance metabolic process#GO:0071704;mRNA splicing, via spliceosome#GO:0000398;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;protein-containing complex organization#GO:0043933;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;ribonucleoprotein complex biogenesis#GO:0022613;mRNA processing#GO:0006397;protein-RNA complex organization#GO:0071826;RNA splicing, via transesterification reactions#GO:0000375 SMN-Sm protein complex#GO:0034719;cytoplasm#GO:0005737;SMN complex#GO:0032797;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;Sm-like protein family complex#GO:0120114;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA splicing factor#PC00148;RNA processing factor#PC00147;RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000008784.3|UniProtKB=F6SDF5 F6SDF5 PTHR18945:SF924 NEUROTRANSMITTER GATED ION CHANNEL NEURONAL ACETYLCHOLINE RECEPTOR SUBUNIT BETA-4-LIKE ISOFORM X1 transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;signaling receptor activity#GO:0038023;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;neurotransmitter receptor activity#GO:0030594;ligand-gated monoatomic ion channel activity#GO:0015276;transporter activity#GO:0005215;channel activity#GO:0015267;transmembrane signaling receptor activity#GO:0004888;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;molecular transducer activity#GO:0060089;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;ligand-gated channel activity#GO:0022834 response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;transmembrane transport#GO:0055085;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;membrane depolarization#GO:0051899;transport#GO:0006810;regulation of membrane potential#GO:0042391;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to nitrogen compound#GO:1901699;localization#GO:0051179;regulation of biological process#GO:0050789;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;cellular response to oxygen-containing compound#GO:1901701;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;synaptic signaling#GO:0099536;monoatomic ion transport#GO:0006811;signaling#GO:0023052;cell-cell signaling#GO:0007267;acetylcholine receptor signaling pathway#GO:0095500 membrane protein complex#GO:0098796;synapse#GO:0045202;plasma membrane signaling receptor complex#GO:0098802;transporter complex#GO:1990351;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;receptor complex#GO:0043235;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;neuron projection#GO:0043005;transmembrane transporter complex#GO:1902495;cell projection#GO:0042995;plasma membrane#GO:0005886 ligand-gated ion channel#PC00141;ion channel#PC00133;transporter#PC00227 CIOIN|Ensembl=ENSCING00000007875.2|UniProtKB=F6TGX7 F6TGX7 PTHR11096:SF0 RNA 3' TERMINAL PHOSPHATE CYCLASE RNA 3'-TERMINAL PHOSPHATE CYCLASE catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on RNA#GO:0140098;ligase activity#GO:0016874;cyclase activity#GO:0009975;catalytic activity#GO:0003824 RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000022729.1|UniProtKB=A0A1W2W6D8 A0A1W2W6D8 LOC100184799 PTHR24418:SF373 TYROSINE-PROTEIN KINASE TYROSINE-PROTEIN KINASE SRC42A protein tyrosine kinase activity#GO:0004713;non-membrane spanning protein tyrosine kinase activity#GO:0004715;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein binding#GO:0005515;catalytic activity, acting on a protein#GO:0140096;signaling receptor binding#GO:0005102;kinase activity#GO:0016301;protein kinase activity#GO:0004672 response to external biotic stimulus#GO:0043207;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;immune response#GO:0006955;developmental process#GO:0032502;cell communication#GO:0007154;cellular process#GO:0009987;defense response to symbiont#GO:0140546;regulation of biological process#GO:0050789;immune system process#GO:0002376;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;cell differentiation#GO:0030154;enzyme-linked receptor protein signaling pathway#GO:0007167;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological process involved in interspecies interaction between organisms#GO:0044419;biological regulation#GO:0065007;innate immune response#GO:0045087;defense response#GO:0006952;signaling#GO:0023052;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169 non-receptor tyrosine protein kinase#PC00168 Parkinson disease#P00049>Src kinase#P01230;Integrin signalling pathway#P00034>Src#P00940 CIOIN|Ensembl=ENSCING00000009409.3|UniProtKB=F6TM37 F6TM37 PTHR11616:SF309 SODIUM/CHLORIDE DEPENDENT TRANSPORTER TRANSPORTER metal ion transport#GO:0030001;transmembrane transport#GO:0055085;amino acid transport#GO:0006865;organic anion transport#GO:0015711;organic acid transport#GO:0015849;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;localization#GO:0051179;organic substance transport#GO:0071702;sodium ion transport#GO:0006814;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;sodium ion transmembrane transport#GO:0035725 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 primary active transporter#PC00068;transporter#PC00227 CIOIN|Ensembl=ENSCING00000024842.1|UniProtKB=H2XMA8 H2XMA8 PTHR12329:SF5 BCL2-ASSOCIATED ATHANOGENE STARVIN, ISOFORM E nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;molecular function regulator activity#GO:0098772;nucleoside phosphate binding#GO:1901265;protein binding#GO:0005515;heterocyclic compound binding#GO:1901363;protein-folding chaperone binding#GO:0051087 biological regulation#GO:0065007;regulation of protein stability#GO:0031647;regulation of biological quality#GO:0065008;protein stabilization#GO:0050821 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;membrane#GO:0016020;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chaperone#PC00072 CIOIN|Ensembl=ENSCING00000002381.3|UniProtKB=F6R4R6 F6R4R6 PTHR12124:SF47 POLYMYOSITIS/SCLERODERMA AUTOANTIGEN-RELATED EXOSOME COMPONENT 10 CIOIN|Ensembl=ENSCING00000024367.1|UniProtKB=H2XT18 H2XT18 PTHR13058:SF19 THREE PRIME REPAIR EXONUCLEASE 1, 2 LD40940P hydrolase activity, acting on ester bonds#GO:0016788;DNA exonuclease activity, producing 5'-phosphomonoesters#GO:0016895;3'-5'-DNA exonuclease activity#GO:0008296;nuclease activity#GO:0004518;DNA exonuclease activity#GO:0004529;catalytic activity#GO:0003824;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters#GO:0016796;hydrolase activity#GO:0016787;catalytic activity, acting on a nucleic acid#GO:0140640;DNA nuclease activity#GO:0004536;catalytic activity, acting on DNA#GO:0140097;exonuclease activity#GO:0004527;3'-5' exonuclease activity#GO:0008408 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;heterocycle catabolic process#GO:0046700;macromolecule metabolic process#GO:0043170;DNA catabolic process#GO:0006308;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular nitrogen compound catabolic process#GO:0044270;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;organic cyclic compound catabolic process#GO:1901361;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;nucleobase-containing compound catabolic process#GO:0034655;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259;cellular catabolic process#GO:0044248 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000004004.3|UniProtKB=A0A1W2W697 A0A1W2W697 LOC100181329 PTHR15335:SF7 PROTEIN TFG PROTEIN TFG localization#GO:0051179;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;establishment of localization#GO:0051234;transport#GO:0006810;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193 cytoplasm#GO:0005737;endoplasmic reticulum exit site#GO:0070971;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150 CIOIN|Ensembl=ENSCING00000002173.2|UniProtKB=F6SSI2 F6SSI2 LOC100176945 PTHR10480:SF12 PROTEIN UNC-13 HOMOLOG UNC-13, ISOFORM E syntaxin binding#GO:0019905;protein binding#GO:0005515;calmodulin binding#GO:0005516;binding#GO:0005488;SNARE binding#GO:0000149 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 CIOIN|Ensembl=ENSCING00000003306.3|UniProtKB=F6W1C5 F6W1C5 LOC100187342 PTHR22842:SF3 WD40 REPEAT PROTEIN WD REPEAT DOMAIN-CONTAINING PROTEIN 83 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704 ribonucleoprotein complex#GO:1990904;catalytic step 2 spliceosome#GO:0071013;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000012766.2|UniProtKB=F6ZQ65 F6ZQ65 PTHR10194:SF148 RAS GTPASE-ACTIVATING PROTEINS GTPASE-ACTIVATING PROTEIN G-protein modulator#PC00022;protein-binding activity modulator#PC00095;GTPase-activating protein#PC00257 EGF receptor signaling pathway#P00018>GAP#P00546;PDGF signaling pathway#P00047>RasGAP#P01152;FGF signaling pathway#P00021>RasGAP#P00646 CIOIN|Ensembl=ENSCING00000006400.3|UniProtKB=F6PQN7 F6PQN7 PTHR10337:SF11 SHC TRANSFORMING PROTEIN DSHC PROTEIN enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;binding#GO:0005488;kinase binding#GO:0019900 scaffold/adaptor protein#PC00226 EGF receptor signaling pathway#P00018>Shc#P00554;PDGF signaling pathway#P00047>Shc#P01175;Integrin signalling pathway#P00034>Shc#P00949;FGF signaling pathway#P00021>Shc#P00639 CIOIN|Ensembl=ENSCING00000011567.2|UniProtKB=F6TBA1 F6TBA1 LOC100182035 PTHR13339:SF0 COP9 SIGNALOSOME COMPLEX SUBUNIT 8 COP9 SIGNALOSOME COMPLEX SUBUNIT 8 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000023993.1|UniProtKB=H2XP88 H2XP88 PTHR24276:SF98 POLYSERASE-RELATED FI18310P1-RELATED serine protease#PC00203;protease#PC00190 CIOIN|Ensembl=ENSCING00000020625.1|UniProtKB=H2Y0C3 H2Y0C3 LOC100180713 PTHR20971:SF0 U6 SNRNA-ASSOCIATED PROTEIN U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM5 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704 U6 snRNP#GO:0005688;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;U4/U6 x U5 tri-snRNP complex#GO:0046540;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;spliceosomal snRNP complex#GO:0097525;protein-containing complex#GO:0032991;small nuclear ribonucleoprotein complex#GO:0030532;spliceosomal tri-snRNP complex#GO:0097526;membrane-bounded organelle#GO:0043227;Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513 RNA splicing factor#PC00148;RNA processing factor#PC00147;RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000003935.3|UniProtKB=F6ZLN5 F6ZLN5 LOC100183884 PTHR10947:SF3 PHENYLALANYL-TRNA SYNTHETASE BETA CHAIN AND LEUCINE-RICH REPEAT-CONTAINING PROTEIN 47 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 47 catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;ligase activity#GO:0016874;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;peptide biosynthetic process#GO:0043043;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622 aminoacyl-tRNA synthetase#PC00047;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000005165.3|UniProtKB=F6TJ44 F6TJ44 LOC100185382 PTHR14609:SF1 RING FINGER PROTEIN 219 ORC UBIQUITIN LIGASE 1 CIOIN|Ensembl=ENSCING00000022284.1|UniProtKB=H2XZ96 H2XZ96 PTHR16200:SF1 RING ZINC FINGER E3 UBIQUITIN-PROTEIN LIGASE PLR-1-RELATED transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000001753.3|UniProtKB=F7A4A9 F7A4A9 PTHR23280:SF21 4.1 G PROTEIN PROTEIN 4.1 HOMOLOG cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165 CIOIN|Ensembl=ENSCING00000014410.2|UniProtKB=F6ZWQ3 F6ZWQ3 PTHR31742:SF1 RPA-INTERACTING PROTEIN RPAIN RPA-INTERACTING PROTEIN cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;protein localization to nucleus#GO:0034504;nitrogen compound transport#GO:0071705;establishment of protein localization to organelle#GO:0072594;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;protein import into nucleus#GO:0006606;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;protein localization to organelle#GO:0033365;nuclear transport#GO:0051169;import into nucleus#GO:0051170 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000005896.3|UniProtKB=F6SH00 F6SH00 PTHR24092:SF218 PROBABLE PHOSPHOLIPID-TRANSPORTING ATPASE PHOSPHOLIPID-TRANSPORTING ATPASE ATPase-coupled intramembrane lipid transporter activity#GO:0140326;ATP-dependent activity#GO:0140657;transporter activity#GO:0005215;lipid transporter activity#GO:0005319 organophosphate ester transport#GO:0015748;macromolecule localization#GO:0033036;membrane organization#GO:0061024;transport#GO:0006810;cellular component organization#GO:0016043;regulation of membrane lipid distribution#GO:0097035;phospholipid transport#GO:0015914;cellular process#GO:0009987;lipid transport#GO:0006869;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;biological regulation#GO:0065007;lipid translocation#GO:0034204;lipid localization#GO:0010876;phospholipid translocation#GO:0045332 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 primary active transporter#PC00068;transporter#PC00227 CIOIN|Ensembl=ENSCING00000009973.3|UniProtKB=F6R046 F6R046 LOC100183285 PTHR12862:SF0 BADF TYPE ATPASE DOMAIN-CONTAINING PROTEIN N-ACETYL-D-GLUCOSAMINE KINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;carbohydrate kinase activity#GO:0019200;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301 CIOIN|Ensembl=ENSCING00000014391.2|UniProtKB=F6ZXS9 F6ZXS9 PTHR19325:SF567 COMPLEMENT COMPONENT-RELATED SUSHI DOMAIN-CONTAINING SUSHI, VON WILLEBRAND FACTOR TYPE A, EGF AND PENTRAXIN DOMAIN-CONTAINING PROTEIN 1-LIKE complement component#PC00078 CIOIN|Ensembl=ENSCING00000008340.3|UniProtKB=F7B499 F7B499 PTHR13090:SF1 ARGININE-HYDROXYLASE NDUFAF5, MITOCHONDRIAL ARGININE-HYDROXYLASE NDUFAF5, MITOCHONDRIAL CIOIN|Ensembl=ENSCING00000019698.1|UniProtKB=H2XXS3 H2XXS3 PTHR24269:SF16 KREMEN PROTEIN PROTEIN SLG1 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 CIOIN|Ensembl=ENSCING00000021217.1|UniProtKB=H2XVU8 H2XVU8 PTHR24044:SF421 NOTCH LIGAND FAMILY MEMBER PROTEIN JAGGED-2 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 intercellular signal molecule#PC00207 Notch signaling pathway#P00045>Next#P01103;Angiogenesis#P00005>Delta/Serrate#P00226;Notch signaling pathway#P00045>Serrate#P01104 CIOIN|Ensembl=ENSCING00000012702.2|UniProtKB=Q4H373 Q4H373 Ci-Mesp PTHR23349:SF112 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, TWIST 48 RELATED 1, ISOFORM B sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 basic helix-loop-helix transcription factor#PC00055 CIOIN|Ensembl=ENSCING00000020697.1|UniProtKB=H2XKB2 H2XKB2 PTHR22802:SF379 C-TYPE LECTIN SUPERFAMILY MEMBER CHONDROITIN SULFATE PROTEOGLYCAN 2 ISOFORM X1 membrane traffic protein#PC00150 CIOIN|Ensembl=ENSCING00000018453.1|UniProtKB=H2XWU4 H2XWU4 PTHR37416:SF1 F-BOX DOMAIN-CONTAINING PROTEIN CYCLIN-LIKE F-BOX CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000009265.3|UniProtKB=F6S202 F6S202 rngi PTHR22922:SF19 GPI-ANCHORED PROTEIN P137 CAPRIN HOMOLOG nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000001690.3|UniProtKB=F6X1H5 F6X1H5 LOC100179283 PTHR45652:SF21 GLIAL FIBRILLARY ACIDIC PROTEIN ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 13-LIKE ISOFORM X1 structural molecule activity#GO:0005198;structural constituent of cytoskeleton#GO:0005200 cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;intermediate filament organization#GO:0045109;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cellular process#GO:0009987;intermediate filament cytoskeleton organization#GO:0045104;intermediate filament-based process#GO:0045103 supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intermediate filament#GO:0005882;intermediate filament cytoskeleton#GO:0045111;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;supramolecular fiber#GO:0099512;supramolecular polymer#GO:0099081;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 intermediate filament#PC00129 CIOIN|Ensembl=ENSCING00000022142.1|UniProtKB=H2XPH6 H2XPH6 PTHR13612:SF0 ENHANCER OF MRNA-DECAPPING PROTEIN 3 ENHANCER OF MRNA-DECAPPING PROTEIN 3 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;cellular component biogenesis#GO:0044085;negative regulation of biological process#GO:0048519;heterocycle catabolic process#GO:0046700;RNA metabolic process#GO:0016070;nucleobase-containing compound metabolic process#GO:0006139;cellular nitrogen compound catabolic process#GO:0044270;regulation of biological process#GO:0050789;RNA decapping#GO:0110154;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;mRNA catabolic process#GO:0006402;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance catabolic process#GO:1901575;P-body assembly#GO:0033962;non-membrane-bounded organelle assembly#GO:0140694;negative regulation of cellular process#GO:0048523;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular component assembly#GO:0022607;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;negative regulation of biosynthetic process#GO:0009890;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;nuclear-transcribed mRNA catabolic process#GO:0000956;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;aromatic compound catabolic process#GO:0019439;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;nucleobase-containing compound catabolic process#GO:0034655;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;P-body#GO:0000932;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic ribonucleoprotein granule#GO:0036464 CIOIN|Ensembl=ENSCING00000006674.3|UniProtKB=F6SR80 F6SR80 LOC100184079 PTHR10334:SF590 CYSTEINE-RICH SECRETORY PROTEIN-RELATED SCP DOMAIN-CONTAINING PROTEIN extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 defense/immunity protein#PC00090 CIOIN|Ensembl=ENSCING00000004212.3|UniProtKB=F7ALA2 F7ALA2 LOC100179163 PTHR22652:SF0 NUCLEOPORIN NUP43 NUCLEOPORIN NUP43 envelope#GO:0031975;nuclear pore#GO:0005643;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;organelle envelope#GO:0031967;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transporter#PC00227 CIOIN|Ensembl=ENSCING00000007795.3|UniProtKB=F6X3V2 F6X3V2 LOC100184638 PTHR45827:SF1 SORTING NEXIN SORTING NEXIN lipid binding#GO:0008289;phosphatidylinositol binding#GO:0035091;phospholipid binding#GO:0005543;binding#GO:0005488 endosomal transport#GO:0016197;cellular localization#GO:0051641;membrane organization#GO:0061024;plasma membrane organization#GO:0007009;transport#GO:0006810;endocytosis#GO:0006897;endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;import into cell#GO:0098657 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000019752.1|UniProtKB=H2XLX1 H2XLX1 PTHR11851:SF226 METALLOPROTEASE CYTOCHROME B-C1 COMPLEX SUBUNIT 2, MITOCHONDRIAL cellular localization#GO:0051641;mitochondrial protein processing#GO:0034982;macromolecule localization#GO:0033036;gene expression#GO:0010467;biosynthetic process#GO:0009058;establishment of protein localization#GO:0045184;protein processing#GO:0016485;establishment of localization#GO:0051234;protein targeting to mitochondrion#GO:0006626;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;protein localization to organelle#GO:0033365;protein metabolic process#GO:0019538;protein processing involved in protein targeting to mitochondrion#GO:0006627;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein targeting#GO:0006605;cellular metabolic process#GO:0044237;establishment of protein localization to organelle#GO:0072594;protein maturation#GO:0051604;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;protein localization to mitochondrion#GO:0070585;protein localization#GO:0008104;primary metabolic process#GO:0044238;localization#GO:0051179;cellular macromolecule localization#GO:0070727;establishment of protein localization to mitochondrion#GO:0072655 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000013254.2|UniProtKB=F6SFT9 F6SFT9 LOC100185341 PTHR34035:SF1 TESTIS-EXPRESSED PROTEIN 47 TESTIS-EXPRESSED PROTEIN 47 CIOIN|Ensembl=ENSCING00000005691.3|UniProtKB=F6XBY1 F6XBY1 PTHR43684:SF1 FAMILY NOT NAMED ENOYL-COA DELTA ISOMERASE 2 CIOIN|Ensembl=ENSCING00000006963.3|UniProtKB=A0A1W3JJN3 A0A1W3JJN3 hox3 PTHR45664:SF18 PROTEIN ZERKNUELLT 1-RELATED HOMEOBOX PROTEIN HOX3 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 CIOIN|Ensembl=ENSCING00000019448.1|UniProtKB=H2Y385 H2Y385 PTHR12241:SF145 TUBULIN POLYGLUTAMYLASE TUBULIN POLYGLUTAMYLASE TTLL5 cytoskeletal protein binding#GO:0008092;ligase activity#GO:0016874;protein binding#GO:0005515;tubulin binding#GO:0015631;catalytic activity, acting on a protein#GO:0140096;binding#GO:0005488;catalytic activity#GO:0003824 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;microtubule cytoskeleton organization#GO:0000226;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;cellular component organization#GO:0016043;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;nitrogen compound metabolic process#GO:0006807;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;microtubule cytoskeleton#GO:0015630;ciliary basal body#GO:0036064;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;cilium#GO:0005929;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;microtubule or microtubule-binding cytoskeletal protein#PC00157 CIOIN|Ensembl=ENSCING00000001597.3|UniProtKB=F6RZT0 F6RZT0 PTHR10454:SF206 CASPASE CASPASE-6 cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197;hydrolase activity#GO:0016787;cysteine-type endopeptidase activity involved in apoptotic process#GO:0097153;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 regulation of biological process#GO:0050789;positive regulation of apoptotic process#GO:0043065;positive regulation of programmed cell death#GO:0043068;regulation of apoptotic process#GO:0042981;regulation of cellular process#GO:0050794;apoptotic process#GO:0006915;biological regulation#GO:0065007;cell death#GO:0008219;programmed cell death#GO:0012501;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;regulation of programmed cell death#GO:0043067;positive regulation of cellular process#GO:0048522 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 protease#PC00190;protein modifying enzyme#PC00260 Huntington disease#P00029>Caspase 6#P00809;FAS signaling pathway#P00020>Caspase6#P00596;FAS signaling pathway#P00020>Pro-Caspase6#P00607 CIOIN|Ensembl=ENSCING00000021112.1|UniProtKB=H2XN25 H2XN25 LOC100180761 PTHR10404:SF81 N-ACETYLATED-ALPHA-LINKED ACIDIC DIPEPTIDASE N-ACETYLATED ALPHA-LINKED ACIDIC DIPEPTIDASE 2 hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;carboxypeptidase activity#GO:0004180 metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000016289.2|UniProtKB=F6QEV8 F6QEV8 PTHR23301:SF0 CHITIN BINDING PERITROPHIN-A CHITIN-BINDING TYPE-2 DOMAIN-CONTAINING PROTEIN-RELATED CIOIN|Ensembl=ENSCING00000024201.1|UniProtKB=H2XP93 H2XP93 PTHR15217:SF0 WILMS' TUMOR 1-ASSOCIATING PROTEIN PRE-MRNA-SPLICING REGULATOR WTAP cellular aromatic compound metabolic process#GO:0006725;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;RNA modification#GO:0009451;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;regulation of mRNA processing#GO:0050684;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;mRNA modification#GO:0016556;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;nucleic acid metabolic process#GO:0090304;macromolecule methylation#GO:0043414;methylation#GO:0032259;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;RNA methylation#GO:0001510;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of metabolic process#GO:0019222;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;regulation of cellular metabolic process#GO:0031323;regulation of mRNA metabolic process#GO:1903311 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000006582.3|UniProtKB=F6R0Z4 F6R0Z4 notrlc PTHR23349:SF68 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, TWIST FI14601P sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 basic helix-loop-helix transcription factor#PC00055 CIOIN|Ensembl=ENSCING00000001720.3|UniProtKB=F6TVY6 F6TVY6 LOC100186572 PTHR12233:SF2 VACUOLAR PROTEIN SORTING 26 RELATED VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 26C localization#GO:0051179;organic substance transport#GO:0071702;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;transport#GO:0006810;protein transport#GO:0015031;nitrogen compound transport#GO:0071705;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104 cytoplasm#GO:0005737;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150 CIOIN|Ensembl=ENSCING00000000163.3|UniProtKB=F6YZ62 F6YZ62 LOC100184065 PTHR42683:SF65 ALDEHYDE REDUCTASE DEATH RESISTOR ADH DOMAIN CONTAINING TARGET, ISOFORM C oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000003199.3|UniProtKB=F6SPY1 F6SPY1 PTHR10164:SF4 ISLET CELL AUTOANTIGEN 1 GH23156P biological regulation#GO:0065007;regulation of biological process#GO:0050789;regulation of localization#GO:0032879;regulation of transport#GO:0051049 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000007942.3|UniProtKB=F6ZRN0 F6ZRN0 LOC100177474 PTHR43806:SF14 PEPTIDASE S8 TRIPEPTIDYL-PEPTIDASE 2 serine-type endopeptidase activity#GO:0004252;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 serine protease#PC00203;protease#PC00190 CIOIN|Ensembl=ENSCING00000000884.3|UniProtKB=F6UPI1 F6UPI1 PTHR10010:SF46 SOLUTE CARRIER FAMILY 34 SODIUM PHOSPHATE , MEMBER 2-RELATED SODIUM-DEPENDENT PHOSPHATE TRANSPORT PROTEIN 2B secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000003864.3|UniProtKB=F6Y4T9 F6Y4T9 PTHR21245:SF15 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN RRM DOMAIN-CONTAINING PROTEIN nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000020497.1|UniProtKB=H2XTS6 H2XTS6 PTHR21325:SF31 PHOSPHOLIPASE B, PLB1 GH22081P-RELATED phospholipase#PC00186 CIOIN|Ensembl=ENSCING00000014579.2|UniProtKB=F6UB39 F6UB39 PTHR34400:SF4 FAMILY NOT NAMED MEMBRANE PROTEIN CIOIN|Ensembl=ENSCING00000005471.3|UniProtKB=F6U602 F6U602 PTHR23001:SF7 EUKARYOTIC TRANSLATION INITIATION FACTOR EUKARYOTIC TRANSLATION INITIATION FACTOR 5 nucleoside-triphosphatase regulator activity#GO:0060589;nucleic acid binding#GO:0003676;translation initiation factor binding#GO:0031369;translation regulator activity#GO:0045182;GTPase regulator activity#GO:0030695;binding#GO:0005488;organic cyclic compound binding#GO:0097159;molecular function regulator activity#GO:0098772;translation initiation factor activity#GO:0003743;protein binding#GO:0005515;translation regulator activity, nucleic acid binding#GO:0090079;enzyme regulator activity#GO:0030234;translation factor activity, RNA binding#GO:0008135 cellular component biogenesis#GO:0044085;peptide metabolic process#GO:0006518;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;translation#GO:0006412;protein-RNA complex assembly#GO:0022618;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular component assembly#GO:0022607;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cytoplasmic translation#GO:0002181;cellular component organization#GO:0016043;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;cytoplasmic translational initiation#GO:0002183;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;cellular component organization or biogenesis#GO:0071840;peptide biosynthetic process#GO:0043043;protein-containing complex organization#GO:0043933;ribonucleoprotein complex biogenesis#GO:0022613;translational initiation#GO:0006413;protein-RNA complex organization#GO:0071826 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 translation initiation factor#PC00224;translation factor#PC00223;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000001232.3|UniProtKB=F6SBR0 F6SBR0 LOC100185814 PTHR24070:SF406 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY SMALL MONOMERIC GTPASE GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;ion binding#GO:0043167;anion binding#GO:0043168 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 small GTPase#PC00208;G-protein#PC00020 Integrin signalling pathway#P00034>Rap1#P00906 CIOIN|Ensembl=ENSCING00000009576.3|UniProtKB=F6TJ71 F6TJ71 PTHR11918:SF45 RADICAL SAM PROTEINS THREONYLCARBAMOYLADENOSINE TRNA METHYLTHIOTRANSFERASE transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;tRNA metabolic process#GO:0006399;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;RNA modification#GO:0009451;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;tRNA modification#GO:0006400;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 CIOIN|Ensembl=ENSCING00000024240.1|UniProtKB=H2Y2U8 H2Y2U8 LOC100185658 PTHR10643:SF2 KINETOCHORE PROTEIN NDC80 KINETOCHORE PROTEIN NDC80 HOMOLOG nuclear chromosome segregation#GO:0098813;cellular localization#GO:0051641;organelle localization#GO:0051640;establishment of chromosome localization#GO:0051303;sister chromatid segregation#GO:0000819;nuclear division#GO:0000280;attachment of mitotic spindle microtubules to kinetochore#GO:0051315;cell cycle process#GO:0022402;cellular component organization#GO:0016043;cellular process#GO:0009987;mitotic cell cycle process#GO:1903047;chromosome segregation#GO:0007059;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;mitotic metaphase chromosome alignment#GO:0007080;establishment of localization#GO:0051234;organelle organization#GO:0006996;chromosome organization#GO:0051276;cell cycle#GO:0007049;mitotic nuclear division#GO:0140014;organelle fission#GO:0048285;establishment of localization in cell#GO:0051649;attachment of spindle microtubules to kinetochore#GO:0008608;mitotic sister chromatid segregation#GO:0000070;chromosome localization#GO:0050000;establishment of organelle localization#GO:0051656;metaphase chromosome alignment#GO:0051310 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;non-membrane-bounded organelle#GO:0043228;outer kinetochore#GO:0000940;protein-containing complex#GO:0032991;kinetochore#GO:0000776;chromosome#GO:0005694;condensed chromosome, centromeric region#GO:0000779;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;chromosomal region#GO:0098687;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transcription cofactor#PC00217 CIOIN|Ensembl=ENSCING00000006171.3|UniProtKB=F7BKI1 F7BKI1 LOC100180771 PTHR31841:SF1 PROTEIN FAM72A-RELATED PROTEIN FAM72A-RELATED cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000008541.3|UniProtKB=F6XQM9 F6XQM9 PTHR23346:SF7 TRANSLATIONAL ACTIVATOR GCN1-RELATED STALLED RIBOSOME SENSOR GCN1 protein kinase regulator activity#GO:0019887;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207 cellular response to stimulus#GO:0051716;regulation of protein metabolic process#GO:0051246;regulation of amide metabolic process#GO:0034248;regulation of nitrogen compound metabolic process#GO:0051171;cell communication#GO:0007154;response to nutrient levels#GO:0031667;response to extracellular stimulus#GO:0009991;cellular process#GO:0009987;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;regulation of cellular biosynthetic process#GO:0031326;response to stress#GO:0006950;cellular response to starvation#GO:0009267;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cellular response to nutrient levels#GO:0031669;regulation of biosynthetic process#GO:0009889;post-transcriptional regulation of gene expression#GO:0010608;response to starvation#GO:0042594;biological regulation#GO:0065007;cellular response to external stimulus#GO:0071496;regulation of translation#GO:0006417;regulation of macromolecule biosynthetic process#GO:0010556;cellular response to amino acid starvation#GO:0034198;regulation of gene expression#GO:0010468;cellular response to stress#GO:0033554;regulation of metabolic process#GO:0019222;cellular response to extracellular stimulus#GO:0031668;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000019579.1|UniProtKB=H2XTM5 H2XTM5 LOC100181925 PTHR46457:SF1 DNA REPAIR PROTEIN RAD51 HOMOLOG 4 DNA REPAIR PROTEIN RAD51 HOMOLOG 4 ATP-dependent activity, acting on DNA#GO:0008094;nucleic acid binding#GO:0003676;ATP-dependent activity#GO:0140657;single-stranded DNA binding#GO:0003697;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on DNA#GO:0140097;four-way junction DNA binding#GO:0000400 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;double-strand break repair#GO:0006302;telomere organization#GO:0032200;nuclear division#GO:0000280;cell cycle process#GO:0022402;nucleobase-containing compound metabolic process#GO:0006139;telomere maintenance#GO:0000723;reciprocal homologous recombination#GO:0140527;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;meiotic cell cycle process#GO:1903046;recombinational repair#GO:0000725;meiosis I cell cycle process#GO:0061982;reciprocal meiotic recombination#GO:0007131;reproductive process#GO:0022414;meiosis I#GO:0007127;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;meiotic cell cycle#GO:0051321;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;double-strand break repair via homologous recombination#GO:0000724;cellular process#GO:0009987;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;reproduction#GO:0000003;organelle organization#GO:0006996;chromosome organization#GO:0051276;meiotic nuclear division#GO:0140013;sexual reproduction#GO:0019953;cell cycle#GO:0007049;organelle fission#GO:0048285;homologous recombination#GO:0035825;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259 microtubule organizing center#GO:0005815;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;nuclear protein-containing complex#GO:0140513;replication fork#GO:0005657 DNA metabolism protein#PC00009 CIOIN|Ensembl=ENSCING00000023503.1|UniProtKB=H2XVM9 H2XVM9 PTHR12802:SF41 SWI/SNF COMPLEX-RELATED BRAHMA ASSOCIATED PROTEIN 155 KDA chromatin/chromatin-binding, or -regulatory protein#PC00077 Wnt signaling pathway#P00057>SWI/SNF#P01435 CIOIN|Ensembl=ENSCING00000017277.2|UniProtKB=F6XYD9 F6XYD9 PTHR43243:SF4 INNER MEMBRANE TRANSPORTER YGJI-RELATED CATIONIC AMINO ACID TRANSPORTER 4 transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;amino acid transmembrane transporter activity#GO:0015171;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215;organic acid transmembrane transporter activity#GO:0005342 localization#GO:0051179;organic substance transport#GO:0071702;establishment of localization#GO:0051234;amino acid transport#GO:0006865;organic anion transport#GO:0015711;organic acid transport#GO:0015849;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942 amino acid transporter#PC00046;transporter#PC00227 CIOIN|Ensembl=ENSCING00000005451.3|UniProtKB=F6UU89 F6UU89 PTHR20921:SF0 TRANSMEMBRANE PROTEIN 222 TRANSMEMBRANE PROTEIN 222 CIOIN|Ensembl=ENSCING00000012212.2|UniProtKB=F6VM60 F6VM60 LOC100180059 PTHR11679:SF1 VESICLE PROTEIN SORTING-ASSOCIATED VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 33B cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 cytoplasm#GO:0005737;endosome#GO:0005768;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular vesicle#GO:0097708;vesicle tethering complex#GO:0099023;vacuole#GO:0005773;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 membrane trafficking regulatory protein#PC00151 CIOIN|Ensembl=ENSCING00000017497.2|UniProtKB=F6T1G9 F6T1G9 PTHR24229:SF109 NEUROPEPTIDES RECEPTOR SOMATOSTATIN RECEPTOR TYPE 2-LIKE neuropeptide binding#GO:0042923;signaling receptor activity#GO:0038023;binding#GO:0005488;peptide binding#GO:0042277;amide binding#GO:0033218;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;neuropeptide signaling pathway#GO:0007218;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;neuron projection#GO:0043005;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 CIOIN|Ensembl=ENSCING00000008861.3|UniProtKB=F6R2Z8 F6R2Z8 LOC100177836 PTHR22699:SF1 THIOREDOXIN DOMAIN-CONTAINING PROTEIN 16 THIOREDOXIN DOMAIN-CONTAINING PROTEIN 16 oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000003978.3|UniProtKB=F6Z0L2 F6Z0L2 PTHR10639:SF7 CLATHRIN LIGHT CHAIN CLATHRIN LIGHT CHAIN protein binding#GO:0005515;clathrin binding#GO:0030276;binding#GO:0005488 localization#GO:0051179;establishment of localization#GO:0051234;clathrin-dependent endocytosis#GO:0072583;transport#GO:0006810;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;receptor-mediated endocytosis#GO:0006898;cellular process#GO:0009987;import into cell#GO:0098657 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;clathrin vesicle coat#GO:0030125;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;coated vesicle#GO:0030135;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;vesicle coat#GO:0030120;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;clathrin-coated vesicle#GO:0030136;membrane coat#GO:0030117;coated vesicle membrane#GO:0030662;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;coated membrane#GO:0048475;cytoplasmic vesicle membrane#GO:0030659;plasma membrane#GO:0005886 vesicle coat protein#PC00235 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Clathrin#P00738;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Clathrin#P00722;Huntington disease#P00029>Clathrin#P00798 CIOIN|Ensembl=ENSCING00000018173.1|UniProtKB=H2XQA5 H2XQA5 LOC100186007 PTHR36978:SF4 P-LOOP CONTAINING NUCLEOTIDE TRIPHOSPHATE HYDROLASE P-LOOP CONTAINING NUCLEOSIDE TRIPHOSPHATE HYDROLASE PROTEIN metabolite interconversion enzyme#PC00262;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000005660.2|UniProtKB=F6Y1V1 F6Y1V1 PTHR45618:SF8 MITOCHONDRIAL DICARBOXYLATE CARRIER-RELATED MITOCHONDRIAL UNCOUPLING PROTEIN 4 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 response to cold#GO:0009409;response to stimulus#GO:0050896;response to temperature stimulus#GO:0009266;response to abiotic stimulus#GO:0009628;response to stress#GO:0006950 secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000001739.3|UniProtKB=F7AMF6 F7AMF6 PTHR10292:SF1 CLATHRIN HEAVY CHAIN RELATED CLATHRIN HEAVY CHAIN protein binding#GO:0005515;clathrin binding#GO:0030276;binding#GO:0005488 localization#GO:0051179;establishment of localization#GO:0051234;transport#GO:0006810;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;receptor-mediated endocytosis#GO:0006898;cellular process#GO:0009987;import into cell#GO:0098657 cytoplasm#GO:0005737;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;membrane coat#GO:0030117;coated membrane#GO:0048475;cellular anatomical entity#GO:0110165;membrane#GO:0016020;intracellular anatomical structure#GO:0005622 vesicle coat protein#PC00235 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Clathrin#P00738;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Clathrin#P00722 CIOIN|Ensembl=ENSCING00000020026.1|UniProtKB=H2XY94 H2XY94 PTHR14453:SF102 PARP/ZINC FINGER CCCH TYPE DOMAIN CONTAINING PROTEIN PROTEIN MONO-ADP-RIBOSYLTRANSFERASE PARP14-LIKE molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;transcription corepressor activity#GO:0003714;catalytic activity#GO:0003824;protein-macromolecule adaptor activity#GO:0030674;catalytic activity, acting on a protein#GO:0140096;pentosyltransferase activity#GO:0016763 negative regulation of gene expression#GO:0010629;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of biosynthetic process#GO:0009890;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;negative regulation of metabolic process#GO:0009892;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biosynthetic process#GO:0009889;nitrogen compound metabolic process#GO:0006807;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000020191.1|UniProtKB=H2XLT6 H2XLT6 PTHR36978:SF4 P-LOOP CONTAINING NUCLEOTIDE TRIPHOSPHATE HYDROLASE P-LOOP CONTAINING NUCLEOSIDE TRIPHOSPHATE HYDROLASE PROTEIN metabolite interconversion enzyme#PC00262;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000006693.3|UniProtKB=F7ARV5 F7ARV5 LOC100181289 PTHR24056:SF46 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE 5 cyclin-dependent protein kinase activity#GO:0097472;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;cyclin-dependent protein serine/threonine kinase activity#GO:0004693;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;phosphorylation#GO:0016310;protein phosphorylation#GO:0006468;cellular process#GO:0009987;protein metabolic process#GO:0019538;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 Nicotine pharmacodynamics pathway#P06587>CDK5#P06597;Axon guidance mediated by semaphorins#P00007>Cdk5#P00336;p53 pathway#P00059>Cdc2#P04634;Dopamine receptor mediated signaling pathway#P05912>CDK5#P05951 CIOIN|Ensembl=ENSCING00000020541.1|UniProtKB=H2XQL0 H2XQL0 PTHR31733:SF1 RIBONUCLEASE KAPPA RIBONUCLEASE KAPPA catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a nucleic acid#GO:0140640;endonuclease activity#GO:0004519;RNA nuclease activity#GO:0004540;RNA endonuclease activity#GO:0004521 endoribonuclease#PC00094;RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000013170.2|UniProtKB=F6YF53 F6YF53 PTHR15241:SF304 TRANSFORMER-2-RELATED RRM DOMAIN-CONTAINING PROTEIN RNA splicing factor#PC00148;RNA processing factor#PC00147 CIOIN|Ensembl=ENSCING00000005115.3|UniProtKB=F7B1J5 F7B1J5 PTHR45617:SF170 LEUCINE RICH REPEAT FAMILY PROTEIN MIP14966P scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000009528.3|UniProtKB=F6UXG6 F6UXG6 LOC100180099 PTHR24068:SF126 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 S ubiquitin-like protein conjugating enzyme activity#GO:0061650;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin conjugating enzyme activity#GO:0061631;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;protein polyubiquitination#GO:0000209;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 Ubiquitin proteasome pathway#P00060>E2#P01491 CIOIN|Ensembl=ENSCING00000025212.1|UniProtKB=Q8HIN2 Q8HIN2 NADH1 PTHR11432:SF3 NADH DEHYDROGENASE SUBUNIT 1 NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 1 NADH dehydrogenase activity#GO:0003954;oxidoreductase activity, acting on NAD(P)H#GO:0016651;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 cellular metabolic process#GO:0044237;cellular respiration#GO:0045333;aerobic respiration#GO:0009060;cellular process#GO:0009987;energy derivation by oxidation of organic compounds#GO:0015980;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152 dehydrogenase#PC00092;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000009272.3|UniProtKB=F6S0X0 F6S0X0 PTHR24031:SF89 RNA HELICASE ATP-DEPENDENT RNA HELICASE DDX31-RELATED cellular component organization or biogenesis#GO:0071840;cellular component biogenesis#GO:0044085;ribosome biogenesis#GO:0042254;cellular process#GO:0009987;ribonucleoprotein complex biogenesis#GO:0022613 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA helicase#PC00032 CIOIN|Ensembl=ENSCING00000001980.3|UniProtKB=F6X3Q7 F6X3Q7 LOC100179496 PTHR11679:SF2 VESICLE PROTEIN SORTING-ASSOCIATED SEC1 FAMILY DOMAIN-CONTAINING PROTEIN 1 syntaxin binding#GO:0019905;protein binding#GO:0005515;binding#GO:0005488;SNARE binding#GO:0000149 endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 bounding membrane of organelle#GO:0098588;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;organelle membrane#GO:0031090;Golgi membrane#GO:0000139;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 membrane trafficking regulatory protein#PC00151 CIOIN|Ensembl=ENSCING00000020779.1|UniProtKB=H2XVS1 H2XVS1 PTHR24300:SF397 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 2U1 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;tetrapyrrole binding#GO:0046906;steroid hydroxylase activity#GO:0008395;oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497;heme binding#GO:0020037 response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;response to chemical#GO:0042221;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 oxygenase#PC00177;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000018264.1|UniProtKB=H2XQ03 H2XQ03 PTHR45639:SF3 HSC70CB, ISOFORM G-RELATED HYPOXIA UP-REGULATED PROTEIN 1 response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;endoplasmic reticulum unfolded protein response#GO:0030968;response to endoplasmic reticulum stress#GO:0034976;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to topologically incorrect protein#GO:0035967;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;response to topologically incorrect protein#GO:0035966;response to unfolded protein#GO:0006986;cellular response to unfolded protein#GO:0034620;biological regulation#GO:0065007;cellular response to stress#GO:0033554;signaling#GO:0023052 cytoplasm#GO:0005737;endoplasmic reticulum protein-containing complex#GO:0140534;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 Hsp70 family chaperone#PC00027 CIOIN|Ensembl=ENSCING00000022619.1|UniProtKB=H2XPC7 H2XPC7 PTHR11592:SF81 GLUTATHIONE PEROXIDASE GLUTATHIONE PEROXIDASE oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;antioxidant activity#GO:0016209;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 peroxidase#PC00180;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000000560.3|UniProtKB=F6Q4K1 F6Q4K1 PTHR42972:SF8 TOL-PAL SYSTEM PROTEIN TOLB POLYHYDROXYBUTYRATE DEPOLYMERASE secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000017199.1|UniProtKB=F6T3J4 F6T3J4 PTHR47456:SF6 PHD-TYPE DOMAIN-CONTAINING PROTEIN SI:DKEY-31C13.1 CIOIN|Ensembl=ENSCING00000004329.3|UniProtKB=F7BN93 F7BN93 PTHR43085:SF55 HEXOKINASE FAMILY MEMBER KETOHEXOKINASE carbohydrate kinase#PC00065 Fructose galactose metabolism#P02744>Ketohexokinase#P02963 CIOIN|Ensembl=ENSCING00000006485.3|UniProtKB=F6Q2F8 F6Q2F8 LOC100177605 PTHR16216:SF2 DYNEIN ASSEMBLY FACTOR 5, AXONEMAL DYNEIN AXONEMAL ASSEMBLY FACTOR 5 chaperone#PC00072 CIOIN|Ensembl=ENSCING00000006528.3|UniProtKB=F6PG92 F6PG92 PTHR11587:SF2 ARGININOSUCCINATE SYNTHASE ARGININOSUCCINATE SYNTHASE ligase activity#GO:0016874;catalytic activity#GO:0003824 proteinogenic amino acid biosynthetic process#GO:0170038;biosynthetic process#GO:0009058;carboxylic acid biosynthetic process#GO:0046394;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;cellular modified amino acid metabolic process#GO:0006575;amino acid biosynthetic process#GO:0008652;alpha-amino acid metabolic process#GO:1901605;amide metabolic process#GO:0043603;L-amino acid metabolic process#GO:0170033;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;organic acid biosynthetic process#GO:0016053;proteinogenic amino acid metabolic process#GO:0170039;oxoacid metabolic process#GO:0043436;arginine metabolic process#GO:0006525;organonitrogen compound biosynthetic process#GO:1901566;cellular metabolic process#GO:0044237;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;alpha-amino acid biosynthetic process#GO:1901607;L-amino acid biosynthetic process#GO:0170034;small molecule biosynthetic process#GO:0044283;carboxylic acid metabolic process#GO:0019752;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ligase#PC00142;metabolite interconversion enzyme#PC00262 Arginine biosynthesis#P02728>Argininosuccinate synthase#P02840 CIOIN|Ensembl=ENSCING00000013440.2|UniProtKB=F6V2T6 F6V2T6 PTHR15129:SF0 SRC-ASSOCIATED ADAPTOR PROTEIN SH3 DOMAIN-CONTAINING PROTEIN cytoplasm#GO:0005737;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000006033.3|UniProtKB=F6SFB8 F6SFB8 PTHR46121:SF4 STEROIDOGENIC ACUTE REGULATORY PROTEIN-LIKE STEROIDOGENIC ACUTE REGULATORY PROTEIN-LIKE localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular localization#GO:0051641;organelle localization#GO:0051640;vesicle localization#GO:0051648;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;transport#GO:0006810;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;cellular component organization#GO:0016043;vesicle targeting#GO:0006903;cellular process#GO:0009987;establishment of organelle localization#GO:0051656 bounding membrane of organelle#GO:0098588;lytic vacuole membrane#GO:0098852;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;late endosome membrane#GO:0031902;vacuole#GO:0005773;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endosome membrane#GO:0010008;organelle membrane contact site#GO:0044232;vesicle#GO:0031982;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;lysosome#GO:0005764;cytoplasmic vesicle membrane#GO:0030659;late endosome#GO:0005770;intracellular vesicle#GO:0097708;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuolar membrane#GO:0005774;organelle subcompartment#GO:0031984;membrane#GO:0016020;lytic vacuole#GO:0000323;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;lysosomal membrane#GO:0005765;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 CIOIN|Ensembl=ENSCING00000015723.2|UniProtKB=F6VWH1 F6VWH1 LOC100176976 PTHR20961:SF148 GLYCOSYLTRANSFERASE EGF DOMAIN-SPECIFIC O-LINKED N-ACETYLGLUCOSAMINE TRANSFERASE transferase activity#GO:0016740;catalytic activity#GO:0003824;glycosyltransferase activity#GO:0016757 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000001424.3|UniProtKB=F6YRS8 F6YRS8 PTHR46295:SF1 ENDOPLASMIC RETICULUM RESIDENT PROTEIN 44 ENDOPLASMIC RETICULUM RESIDENT PROTEIN 44 isomerase activity#GO:0016853;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;protein disulfide isomerase activity#GO:0003756 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein folding#GO:0006457;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;endoplasmic reticulum membrane#GO:0005789 CIOIN|Ensembl=ENSCING00000004876.3|UniProtKB=F6SPI0 F6SPI0 PTHR24188:SF29 ANKYRIN REPEAT PROTEIN GH09064P CIOIN|Ensembl=ENSCING00000002135.3|UniProtKB=F6WRB6 F6WRB6 LOC100185206 PTHR13624:SF6 RE42071P EMEI CIOIN|Ensembl=ENSCING00000007291.2|UniProtKB=F6S8A1 F6S8A1 LOC100182958 PTHR10671:SF34 EPITHELIAL MEMBRANE PROTEIN-RELATED PROTEIN NKG7 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cytoskeletal protein#PC00085 CIOIN|Ensembl=ENSCING00000004728.3|UniProtKB=A0A1W3JT05 A0A1W3JT05 LOC100178100 PTHR12925:SF0 HIKESHI FAMILY MEMBER PROTEIN HIKESHI cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;protein localization to nucleus#GO:0034504;nitrogen compound transport#GO:0071705;establishment of protein localization to organelle#GO:0072594;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;protein import into nucleus#GO:0006606;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;protein localization to organelle#GO:0033365;nuclear transport#GO:0051169;import into nucleus#GO:0051170 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000014948.2|UniProtKB=F6VKI2 F6VKI2 LOC100183852 PTHR22957:SF26 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN LD44506P nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 regulation of molecular function#GO:0065009;regulation of GTPase activity#GO:0043087;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;activation of GTPase activity#GO:0090630;biological regulation#GO:0065007;positive regulation of molecular function#GO:0044093;regulation of hydrolase activity#GO:0051336;regulation of catalytic activity#GO:0050790;positive regulation of hydrolase activity#GO:0051345 GTPase-activating protein#PC00257 CIOIN|Ensembl=ENSCING00000010004.3|UniProtKB=F6QM62 F6QM62 PTHR24064:SF577 SOLUTE CARRIER FAMILY 22 MEMBER GH09241P secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000002052.3|UniProtKB=F6TGT7 F6TGT7 PTHR24339:SF28 HOMEOBOX PROTEIN EMX-RELATED E5-RELATED sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 CIOIN|Ensembl=ENSCING00000002393.3|UniProtKB=F6QZW7 F6QZW7 PTHR21258:SF55 DOCKING PROTEIN RELATED FI23523P1 molecular adaptor activity#GO:0060090;signaling adaptor activity#GO:0035591;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;growth factor receptor binding#GO:0070851;enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;protein tyrosine kinase binding#GO:1990782;signaling receptor complex adaptor activity#GO:0030159;receptor tyrosine kinase binding#GO:0030971;signaling receptor binding#GO:0005102;kinase binding#GO:0019900;fibroblast growth factor receptor binding#GO:0005104 fibroblast growth factor receptor signaling pathway#GO:0008543;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cellular response to endogenous stimulus#GO:0071495;response to growth factor#GO:0070848;cell communication#GO:0007154;cellular process#GO:0009987;response to fibroblast growth factor#GO:0071774;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to endogenous stimulus#GO:0009719;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of cellular process#GO:0050794;cellular response to growth factor stimulus#GO:0071363;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cellular response to fibroblast growth factor stimulus#GO:0044344;signaling#GO:0023052;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000022626.1|UniProtKB=Q4H376 Q4H376 Ci-Max PTHR10328:SF3 PROTEIN MAX MYC-ASSOCIATED FACTOR X PROTEIN MAX transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of RNA metabolic process#GO:0051254;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 basic helix-loop-helix transcription factor#PC00055 Oxidative stress response#P00046>Max#P01133 CIOIN|Ensembl=ENSCING00000012436.2|UniProtKB=F6VI88 F6VI88 PTHR46292:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 102A COILED-COIL DOMAIN-CONTAINING PROTEIN 102A CIOIN|Ensembl=ENSCING00000023107.1|UniProtKB=H2XLI1 H2XLI1 PTHR10760:SF2 TORSIN LD13476P-RELATED chaperone#PC00072 Parkinson disease#P00049>Torsin A#P01221 CIOIN|Ensembl=ENSCING00000006328.3|UniProtKB=F6PYG2 F6PYG2 LOC100179946 PTHR46052:SF1 PHOSDUCIN-LIKE PROTEIN PHOSDUCIN-LIKE PROTEIN CIOIN|Ensembl=ENSCING00000010542.3|UniProtKB=F6YS75 F6YS75 LOC100186360 PTHR14791:SF29 BOMB/KIRA PROTEINS PROTEIN KIBRA CIOIN|Ensembl=ENSCING00000005192.3|UniProtKB=F7B6Z2 F7B6Z2 PTHR10048:SF118 PHOSPHATIDYLINOSITOL KINASE PI-3 KINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301;lipid kinase activity#GO:0001727 lipid metabolic process#GO:0006629;signal transduction#GO:0007165;phospholipid biosynthetic process#GO:0008654;organophosphate biosynthetic process#GO:0090407;phosphatidylinositol biosynthetic process#GO:0006661;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;lipid biosynthetic process#GO:0008610;phosphatidylinositol phosphate biosynthetic process#GO:0046854;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;glycerolipid metabolic process#GO:0046486;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;signaling#GO:0023052;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular response to stimulus#GO:0051716;glycerolipid biosynthetic process#GO:0045017;cellular metabolic process#GO:0044237;cell communication#GO:0007154;glycerophospholipid metabolic process#GO:0006650;phosphatidylinositol metabolic process#GO:0046488;cell motility#GO:0048870;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0043491;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;glycerophospholipid biosynthetic process#GO:0046474;biological regulation#GO:0065007;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;cell migration#GO:0016477 cytoplasm#GO:0005737;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;phosphatidylinositol 3-kinase complex#GO:0005942;catalytic complex#GO:1902494;transferase complex#GO:1990234;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695;extrinsic component of membrane#GO:0019898 kinase#PC00137 PDGF signaling pathway#P00047>PI3K#P01168;Apoptosis signaling pathway#P00006>PI3K#P00310;Hypoxia response via HIF activation#P00030>PI3K#P00823;Axon guidance mediated by netrin#P00009>PI3K#P00363;PI3 kinase pathway#P00048>p110#P01192;EGF receptor signaling pathway#P00018>PI3K#P00557;VEGF signaling pathway#P00056>PI3K#P01413;FGF signaling pathway#P00021>PI3K#P00640;p53 pathway feedback loops 2#P04398>PI3K#P04661;Endothelin signaling pathway#P00019>PI3K#P00577;Integrin signalling pathway#P00034>PI3K#P00936;Angiogenesis#P00005>PI3K#P00236;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PI3K#P00868;Ras Pathway#P04393>PI3K#P04567;p53 pathway#P00059>PI3K#P04609;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>PI3K#P00900;PI3 kinase pathway#P00048>P110ACT#P01177 CIOIN|Ensembl=ENSCING00000009069.3|UniProtKB=F6QJ41 F6QJ41 LOC100179038 PTHR45679:SF2 ER DEGRADATION-ENHANCING ALPHA-MANNOSIDASE-LIKE PROTEIN 2 ER DEGRADATION-ENHANCING ALPHA-MANNOSIDASE-LIKE PROTEIN 3 hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 carbohydrate derivative metabolic process#GO:1901135;macromolecule modification#GO:0043412;protein catabolic process#GO:0030163;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;glycoprotein metabolic process#GO:0009100;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;macromolecule catabolic process#GO:0009057;response to endoplasmic reticulum stress#GO:0034976;response to oxygen-containing compound#GO:1901700;macromolecule metabolic process#GO:0043170;carbohydrate derivative catabolic process#GO:1901136;organonitrogen compound metabolic process#GO:1901564;ERAD pathway#GO:0036503;response to organonitrogen compound#GO:0010243;cellular process#GO:0009987;primary metabolic process#GO:0044238;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;cellular response to stress#GO:0033554 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000001603.3|UniProtKB=F6RZS3 F6RZS3 PTHR16088:SF3 YY1 ASSOCIATED PROTEIN-RELATED GON-4-LIKE PROTEIN molecular adaptor activity#GO:0060090;transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;protein-macromolecule adaptor activity#GO:0030674 regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transcription cofactor#PC00217 CIOIN|Ensembl=ENSCING00000018544.1|UniProtKB=H2XKV3 H2XKV3 PTHR23119:SF50 DISCS LARGE PDZ DOMAIN-CONTAINING PROTEIN enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;binding#GO:0005488;kinase binding#GO:0019900 endosomal transport#GO:0016197;establishment or maintenance of cell polarity#GO:0007163;cellular localization#GO:0051641;establishment or maintenance of epithelial cell apical/basal polarity#GO:0045197;macromolecule localization#GO:0033036;transport#GO:0006810;developmental process#GO:0032502;nitrogen compound transport#GO:0071705;establishment of protein localization#GO:0045184;organic substance transport#GO:0071702;establishment of protein localization to membrane#GO:0090150;endocytic recycling#GO:0032456;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;neurotransmitter receptor transport to postsynaptic membrane#GO:0098969;establishment or maintenance of apical/basal cell polarity#GO:0035088;protein localization to organelle#GO:0033365;regulation of postsynaptic membrane neurotransmitter receptor levels#GO:0099072;protein localization to plasma membrane#GO:0072659;localization within membrane#GO:0051668;vesicle-mediated transport to the plasma membrane#GO:0098876;protein localization to synapse#GO:0035418;protein localization to membrane#GO:0072657;multicellular organism development#GO:0007275;vesicle-mediated transport#GO:0016192;establishment of protein localization to organelle#GO:0072594;cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987;protein localization#GO:0008104;localization#GO:0051179;protein localization to cell periphery#GO:1990778;embryo development#GO:0009790;cellular macromolecule localization#GO:0070727;protein localization to cell junction#GO:1902414;anatomical structure development#GO:0048856;protein transport#GO:0015031;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;multicellular organismal process#GO:0032501;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;receptor clustering#GO:0043113;establishment or maintenance of bipolar cell polarity#GO:0061245;protein-containing complex localization#GO:0031503 synapse#GO:0045202;postsynaptic specialization#GO:0099572;postsynaptic density#GO:0014069;postsynaptic membrane#GO:0045211;cell-cell junction#GO:0005911;basolateral plasma membrane#GO:0016323;anchoring junction#GO:0070161;cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;neuron to neuron synapse#GO:0098984;membrane#GO:0016020;synaptic membrane#GO:0097060;asymmetric synapse#GO:0032279;basal plasma membrane#GO:0009925;plasma membrane region#GO:0098590;postsynapse#GO:0098794;adherens junction#GO:0005912;basal part of cell#GO:0045178;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000002162.3|UniProtKB=F6TEA0 F6TEA0 LOC100186347 PTHR10210:SF53 RIBOSE-PHOSPHATE DIPHOSPHOKINASE FAMILY MEMBER GH23275P carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;transferase activity#GO:0016740;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;transferase activity, transferring phosphorus-containing groups#GO:0016772;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;anion binding#GO:0043168;ATP binding#GO:0005524 cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;ribose phosphate biosynthetic process#GO:0046390;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695 nucleotide kinase#PC00172;kinase#PC00137 CIOIN|Ensembl=ENSCING00000023748.1|UniProtKB=H2XMG7 H2XMG7 PTHR12835:SF5 BIOTIN PROTEIN LIGASE BIOTIN--PROTEIN LIGASE ligase activity#GO:0016874;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ligase#PC00142;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000011871.2|UniProtKB=F6Z277 F6Z277 PTHR10126:SF69 TATA-BOX BINDING PROTEIN TATA BOX-BINDING PROTEIN-LIKE 1 cellular aromatic compound metabolic process#GO:0006725;DNA-templated transcription#GO:0006351;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;gene expression#GO:0010467;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;DNA-templated transcription initiation#GO:0006352;aromatic compound biosynthetic process#GO:0019438;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 RNA metabolism protein#PC00031;general transcription factor#PC00259 General transcription by RNA polymerase I#P00022>SL1 complex#P00653;General transcription by RNA polymerase I#P00022>TBP#P00657;General transcription regulation#P00023>TBP#P00670;Transcription regulation by bZIP transcription factor#P00055>TBP#P01399 CIOIN|Ensembl=ENSCING00000002845.3|UniProtKB=F6TN99 F6TN99 PTHR12889:SF0 GAMMA-SECRETASE SUBUNIT APH-1 GAMMA-SECRETASE SUBUNIT APH-1 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;protein processing#GO:0016485;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;plasma membrane#GO:0005886 protease#PC00190;protein modifying enzyme#PC00260 Alzheimer disease-presenilin pathway#P00004>Aph-1#P00170;Notch signaling pathway#P00045>Aph-1#P01109;Alzheimer disease-amyloid secretase pathway#P00003>Aph-1#P00091 CIOIN|Ensembl=ENSCING00000004644.3|UniProtKB=F6RNG3 F6RNG3 LOC100184383 PTHR46708:SF9 TENASCIN FIBRONECTIN extracellular matrix protein#PC00102 CIOIN|Ensembl=ENSCING00000007977.3|UniProtKB=F6WRI2 F6WRI2 LOC113474198 PTHR15710:SF160 E3 UBIQUITIN-PROTEIN LIGASE PRAJA E3 UBIQUITIN-PROTEIN LIGASE RNF181 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000017235.2|UniProtKB=F6QXZ7 F6QXZ7 PTHR21610:SF9 VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 8 VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 8 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000006231.3|UniProtKB=Q4H2N7 Q4H2N7 Ci-TTF1 PTHR24340:SF41 HOMEOBOX PROTEIN NKX MUSCLE-SPECIFIC HOMEOBOX PROTEIN TINMAN-RELATED sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 CIOIN|Ensembl=ENSCING00000022402.1|UniProtKB=H2XMJ7 H2XMJ7 PTHR11200:SF275 INOSITOL 5-PHOSPHATASE LD06095P hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 lipid metabolic process#GO:0006629;phospholipid dephosphorylation#GO:0046839;phosphatidylinositol dephosphorylation#GO:0046856;cellular metabolic process#GO:0044237;phosphatidylinositol metabolic process#GO:0046488;glycerophospholipid metabolic process#GO:0006650;lipid modification#GO:0030258;cellular process#GO:0009987;phospholipid metabolic process#GO:0006644;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;dephosphorylation#GO:0016311;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 metabolite interconversion enzyme#PC00262;phosphatase#PC00181 CIOIN|Ensembl=ENSCING00000006645.3|UniProtKB=Q4H3W1 Q4H3W1 Ci-ATF2_7 PTHR19304:SF5 CYCLIC-AMP RESPONSE ELEMENT BINDING PROTEIN ACTIVATING TRANSCRIPTION FACTOR-2 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 DNA-binding transcription factor#PC00218;basic leucine zipper transcription factor#PC00056 CIOIN|Ensembl=ENSCING00000005627.3|UniProtKB=F7A9M5 F7A9M5 PTHR13239:SF4 PROTEIN REQUIRED FOR HYPHAL ANASTOMOSIS HAM-2 AT25231P cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cellular process#GO:0009987;organelle organization#GO:0006996 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000024431.1|UniProtKB=H2XU21 H2XU21 PTHR24044:SF417 NOTCH LIGAND FAMILY MEMBER WEARY, ISOFORM B protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 intercellular signal molecule#PC00207 CIOIN|Ensembl=ENSCING00000018511.1|UniProtKB=H2XW06 H2XW06 PTHR23055:SF70 CALCIUM BINDING PROTEINS EF-HAND DOMAIN-CONTAINING PROTEIN cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488 calmodulin-related#PC00061 CIOIN|Ensembl=ENSCING00000001420.3|UniProtKB=A0A1W5BDE9 A0A1W5BDE9 LOC100180439 PTHR13416:SF2 FAMILY NOT NAMED TRANSMEMBRANE PROTEIN 43 lipid metabolic process#GO:0006629;organic substance metabolic process#GO:0071704;primary metabolic process#GO:0044238;metabolic process#GO:0008152 CIOIN|Ensembl=ENSCING00000013439.2|UniProtKB=F6ZDN7 F6ZDN7 PTHR11662:SF454 SOLUTE CARRIER FAMILY 17 SIALIN-LIKE transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 localization#GO:0051179;monoatomic ion transport#GO:0006811;establishment of localization#GO:0051234;monoatomic anion transport#GO:0006820;transport#GO:0006810 plasma membrane region#GO:0098590;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;apical part of cell#GO:0045177;plasma membrane#GO:0005886;apical plasma membrane#GO:0016324 secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000012795.2|UniProtKB=F6WQN6 F6WQN6 PTHR11716:SF47 PHOSPHOLIPASE A2 FAMILY MEMBER PHOSPHOLIPASE A2-ALPHA phospholipase#PC00186 CIOIN|Ensembl=ENSCING00000004569.3|UniProtKB=F6XCC4 F6XCC4 PTHR24033:SF224 EGF-LIKE DOMAIN-CONTAINING PROTEIN C-TYPE LECTIN CIOIN|Ensembl=ENSCING00000000623.3|UniProtKB=F6RRP3 F6RRP3 PTHR22901:SF0 SIALATE O-ACETYLESTERASE SIALATE O-ACETYLESTERASE hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 carbohydrate metabolic process#GO:0005975;organic substance metabolic process#GO:0071704;primary metabolic process#GO:0044238;metabolic process#GO:0008152 esterase#PC00097 CIOIN|Ensembl=ENSCING00000006773.3|UniProtKB=F6VEU2 F6VEU2 PTHR45843:SF1 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-LIKE 4 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-LIKE 4 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chaperone#PC00072 CIOIN|Ensembl=ENSCING00000012312.2|UniProtKB=F7AVQ6 F7AVQ6 PTHR28642:SF1 MEIOSIS 1 ARREST PROTEIN MEIOSIS 1 ARREST PROTEIN male gamete generation#GO:0048232;nuclear chromosome segregation#GO:0098813;chromosome separation#GO:0051304;gamete generation#GO:0007276;cellular process involved in reproduction in multicellular organism#GO:0022412;multicellular organism reproduction#GO:0032504;meiotic cell cycle#GO:0051321;nuclear division#GO:0000280;developmental process#GO:0032502;cell cycle process#GO:0022402;cellular component organization#GO:0016043;cellular process#GO:0009987;meiotic chromosome segregation#GO:0045132;chromosome segregation#GO:0007059;developmental process involved in reproduction#GO:0003006;cellular component organization or biogenesis#GO:0071840;reproduction#GO:0000003;meiotic nuclear division#GO:0140013;organelle organization#GO:0006996;meiotic cell cycle process#GO:1903046;spermatogenesis#GO:0007283;sexual reproduction#GO:0019953;reproductive process#GO:0022414;cell cycle#GO:0007049;organelle fission#GO:0048285;multicellular organismal process#GO:0032501;male meiotic nuclear division#GO:0007140;multicellular organismal reproductive process#GO:0048609 CIOIN|Ensembl=ENSCING00000000605.3|UniProtKB=F6PHT0 F6PHT0 PTHR24033:SF232 EGF-LIKE DOMAIN-CONTAINING PROTEIN LAMININ SUBUNIT GAMMA-2-RELATED Notch signaling pathway#P00045>Notch#P01099;Integrin signalling pathway#P00034>Laminin#P00947;Notch signaling pathway#P00045>NIct#P01119;Notch signaling pathway#P00045>NIcs#P01120;Notch signaling pathway#P00045>Ntm#P01114 CIOIN|Ensembl=ENSCING00000018042.1|UniProtKB=Q4H2R3 Q4H2R3 Ci-SRF PTHR48019:SF134 SERUM RESPONSE FACTOR HOMOLOG SERUM RESPONSE FACTOR HOMOLOG sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 MADS box transcription factor#PC00250 PDGF signaling pathway#P00047>SRF#P01165 CIOIN|Ensembl=ENSCING00000006453.3|UniProtKB=F6QKK4 F6QKK4 LOC100183479 PTHR22677:SF3 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 60 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 60 CIOIN|Ensembl=ENSCING00000019099.1|UniProtKB=H2XVC9 H2XVC9 PTHR11214:SF283 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE N-ACETYLLACTOSAMINIDE BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE 4-LIKE transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;protein O-linked glycosylation#GO:0006493;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 bounding membrane of organelle#GO:0098588;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;Golgi membrane#GO:0000139;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111 CIOIN|Ensembl=ENSCING00000013061.2|UniProtKB=A0A1W2W7V1 A0A1W2W7V1 LOC100179846 PTHR43289:SF14 MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 20-RELATED LYMPHOKINE-ACTIVATED KILLER T-CELL-ORIGINATED PROTEIN KINASE transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;peptidyl-amino acid modification#GO:0018193;cellular process#GO:0009987;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;nitrogen compound metabolic process#GO:0006807;peptidyl-serine modification#GO:0018209;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000007176.3|UniProtKB=F6ZAV7 F6ZAV7 PTHR19325:SF560 COMPLEMENT COMPONENT-RELATED SUSHI DOMAIN-CONTAINING SUSHI, VON WILLEBRAND FACTOR TYPE A, EGF AND PENTRAXIN DOMAIN-CONTAINING PROTEIN 1 complement component#PC00078 CIOIN|Ensembl=ENSCING00000009495.3|UniProtKB=F6Y9D9 F6Y9D9 PTHR45702:SF2 ADAM10/ADAM17 METALLOPEPTIDASE FAMILY MEMBER KUZBANIAN, ISOFORM A hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 membrane protein proteolysis#GO:0033619;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;membrane protein ectodomain proteolysis#GO:0006509;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 protease#PC00190;protein modifying enzyme#PC00260 Alzheimer disease-amyloid secretase pathway#P00003>ADAM10#P00108 CIOIN|Ensembl=ENSCING00000012172.2|UniProtKB=F6TV13 F6TV13 PTHR10704:SF71 CARBOHYDRATE SULFOTRANSFERASE CARBOHYDRATE SULFOTRANSFERASE 1-LIKE sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824 cellular metabolic process#GO:0044237;amino sugar metabolic process#GO:0006040;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000002180.3|UniProtKB=F6SS10 F6SS10 LOC100182351 PTHR24261:SF7 PLASMINOGEN-RELATED KRINGLE DOMAIN-CONTAINING PROTEIN serine protease#PC00203;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000001084.3|UniProtKB=F7B0D1 F7B0D1 PTHR10963:SF55 GLYCOSYL HYDROLASE-RELATED GLYCOSIDE HYDROLASE FAMILY 16 PROTEIN glucosidase#PC00108;metabolite interconversion enzyme#PC00262;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000002881.3|UniProtKB=F6T047 F6T047 PTHR21428:SF11 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 7 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 7 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;core mediator complex#GO:0070847;RNA polymerase II transcription regulator complex#GO:0090575;mediator complex#GO:0016592;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031;general transcription factor#PC00259 CIOIN|Ensembl=ENSCING00000023631.1|UniProtKB=H2XZH4 H2XZH4 LOC100184282 PTHR10845:SF259 REGULATOR OF G PROTEIN SIGNALING RGS DOMAIN-CONTAINING PROTEIN-RELATED G-protein modulator#PC00022;protein-binding activity modulator#PC00095;GTPase-activating protein#PC00257 CIOIN|Ensembl=ENSCING00000006976.3|UniProtKB=F6SYZ4 F6SYZ4 PTHR45638:SF19 CYCLIC NUCLEOTIDE-GATED CATION CHANNEL SUBUNIT A CYCLIC NUCLEOTIDE-BINDING DOMAIN-CONTAINING PROTEIN monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;binding#GO:0005488;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated potassium channel activity#GO:0005249;channel activity#GO:0015267;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;protein-containing complex binding#GO:0044877;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;inorganic cation transmembrane transporter activity#GO:0022890 ligand-gated ion channel#PC00141;ion channel#PC00133;transporter#PC00227 CIOIN|Ensembl=ENSCING00000019724.1|UniProtKB=H2Y1L4 H2Y1L4 PTHR43243:SF17 INNER MEMBRANE TRANSPORTER YGJI-RELATED CATIONIC AMINO ACID TRANSPORTER-RELATED transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;amino acid transmembrane transporter activity#GO:0015171;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215;organic acid transmembrane transporter activity#GO:0005342 localization#GO:0051179;organic substance transport#GO:0071702;establishment of localization#GO:0051234;amino acid transport#GO:0006865;organic anion transport#GO:0015711;organic acid transport#GO:0015849;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 amino acid transporter#PC00046;transporter#PC00227 CIOIN|Ensembl=ENSCING00000013010.2|UniProtKB=F6UHF9 F6UHF9 PTHR10036:SF25 CD59 GLYCOPROTEIN HEP21 PROTEIN CIOIN|Ensembl=ENSCING00000003184.3|UniProtKB=F6SQF6 F6SQF6 LOC100185133 PTHR12093:SF10 NCK-ASSOCIATED PROTEIN 1 MEMBRANE-ASSOCIATED PROTEIN HEM cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cell projection organization#GO:0030030;developmental process#GO:0032502;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;cell motility#GO:0048870;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;anatomical structure morphogenesis#GO:0009653;organelle organization#GO:0006996;anatomical structure development#GO:0048856;cortical cytoskeleton organization#GO:0030865;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;cell migration#GO:0016477;cortical actin cytoskeleton organization#GO:0030866 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000000894.3|UniProtKB=F6U1K7 F6U1K7 PTHR11685:SF212 RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING E3 UBIQUITIN-PROTEIN LIGASE ARIH1 ubiquitin-like protein conjugating enzyme binding#GO:0044390;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;enzyme binding#GO:0019899;protein binding#GO:0005515;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;protein polyubiquitination#GO:0000209;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000008336.3|UniProtKB=F7B4B8 F7B4B8 PTHR45876:SF8 FI04035P FI04035P nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047;GTPase regulator activity#GO:0030695;molecular function activator activity#GO:0140677;GTPase activator activity#GO:0005096;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000006179.3|UniProtKB=F7BK53 F7BK53 LOC100185291 PTHR13243:SF1 HSPC111 PROTEIN-RELATED NUCLEOLAR PROTEIN 16 cellular component organization or biogenesis#GO:0071840;cellular component biogenesis#GO:0044085;ribosome biogenesis#GO:0042254;cellular process#GO:0009987;ribosomal large subunit biogenesis#GO:0042273;ribonucleoprotein complex biogenesis#GO:0022613 membrane-enclosed lumen#GO:0031974;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000010423.3|UniProtKB=F6R2C6 F6R2C6 LOC100184647 PTHR12850:SF5 40S RIBOSOMAL PROTEIN S25 SMALL RIBOSOMAL SUBUNIT PROTEIN ES25 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic small ribosomal subunit#GO:0022627;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;small ribosomal subunit#GO:0015935;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000007067.3|UniProtKB=Q4H3L5 Q4H3L5 Ci-ERK1_2 PTHR24055:SF599 MITOGEN-ACTIVATED PROTEIN KINASE MITOGEN-ACTIVATED PROTEIN KINASE ERK-A transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;signaling#GO:0023052 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 EGF receptor signaling pathway#P00018>ERK1-2#P00543;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>MAPK#P00835;FGF signaling pathway#P00021>ERK1-2#P00627;Interferon-gamma signaling pathway#P00035>Serine kinase#P00955;Alzheimer disease-amyloid secretase pathway#P00003>MAPK#P00099;Apoptosis signaling pathway#P00006>MAPK#P00269;TGF-beta signaling pathway#P00052>p42/p44MAPKs#P01293;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>ERK#P00889;Parkinson disease#P00049>ERK#P01211;Endothelin signaling pathway#P00019>ERK#P00566 CIOIN|Gene=MTND_CIOIN|UniProtKB=F6W3G8 F6W3G8 PTHR23418:SF0 ACIREDUCTONE DIOXYGENASE ACIREDUCTONE DIOXYGENASE oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;dioxygenase activity#GO:0051213 oxoacid metabolic process#GO:0043436;proteinogenic amino acid metabolic process#GO:0170039;sulfur compound metabolic process#GO:0006790;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;alpha-amino acid metabolic process#GO:1901605;aspartate family amino acid metabolic process#GO:0009066;carboxylic acid metabolic process#GO:0019752;L-amino acid metabolic process#GO:0170033;amino acid metabolic process#GO:0006520;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152 oxygenase#PC00177;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000022686.1|UniProtKB=H2XSG4 H2XSG4 PTHR15898:SF18 BIFUNCTIONAL APOPTOSIS REGULATOR GLUCOSE-INDUCED DEGRADATION PROTEIN 4 HOMOLOG transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000007874.3|UniProtKB=F6TGU6 F6TGU6 PTHR46047:SF3 TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 61F TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 61F hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;protein tyrosine phosphatase activity#GO:0004725;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578;kinase binding#GO:0019900 regulation of MAPK cascade#GO:0043408;negative regulation of biological process#GO:0048519;peptidyl-tyrosine dephosphorylation#GO:0035335;macromolecule modification#GO:0043412;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;protein modification process#GO:0036211;regulation of intracellular signal transduction#GO:1902531;regulation of receptor signaling pathway via STAT#GO:1904892;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;negative regulation of MAPK cascade#GO:0043409;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of cell communication#GO:0010646;negative regulation of response to stimulus#GO:0048585;macromolecule metabolic process#GO:0043170;negative regulation of signaling#GO:0023057;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein dephosphorylation#GO:0006470;cellular process#GO:0009987;primary metabolic process#GO:0044238;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;regulation of ERK1 and ERK2 cascade#GO:0070372;dephosphorylation#GO:0016311;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;regulation of receptor signaling pathway via JAK-STAT#GO:0046425 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein phosphatase#PC00195;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000002081.4|UniProtKB=F7AA42 F7AA42 LOC100186483 PTHR24031:SF727 RNA HELICASE ATP-DEPENDENT RNA HELICASE DDX47-RELATED RNA helicase#PC00032 CIOIN|Ensembl=ENSCING00000004031.3|UniProtKB=F6SKF5 F6SKF5 PTHR10037:SF230 VOLTAGE-GATED CATION CHANNEL CALCIUM AND SODIUM CA[2+]-CHANNEL PROTEIN ALPHA[[1]] SUBUNIT T, ISOFORM F calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;calcium channel activity#GO:0005262;voltage-gated channel activity#GO:0022832;sodium ion transmembrane transporter activity#GO:0015081;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;channel activity#GO:0015267;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated calcium channel activity#GO:0005245;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;sodium channel activity#GO:0005272;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 localization#GO:0051179;calcium ion import#GO:0070509;metal ion transport#GO:0030001;establishment of localization#GO:0051234;regulation of biological quality#GO:0065008;membrane depolarization#GO:0051899;transport#GO:0006810;regulation of membrane potential#GO:0042391;biological regulation#GO:0065007;monoatomic cation transport#GO:0006812;action potential#GO:0001508;monoatomic ion transport#GO:0006811;calcium ion transport#GO:0006816 membrane protein complex#GO:0098796;sodium channel complex#GO:0034706;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;neuron projection#GO:0043005;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;cation channel complex#GO:0034703;plasma membrane#GO:0005886 transporter#PC00227;voltage-gated ion channel#PC00241 CIOIN|Ensembl=ENSCING00000012316.2|UniProtKB=F7AVD2 F7AVD2 PTHR19300:SF57 BETA-1,4-GALACTOSYLTRANSFERASE BETA-1,4-N-ACETYLGALACTOSAMINYLTRANSFERASE galactosyltransferase activity#GO:0008378;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 glycosylation#GO:0070085;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000006539.3|UniProtKB=F6RNR5 F6RNR5 PTHR14226:SF29 NEUROPATHY TARGET ESTERASE/SWISS CHEESE D.MELANOGASTER NEUROPATHY TARGET ESTERASE SWS esterase#PC00097;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000015868.2|UniProtKB=F6ZII8 F6ZII8 LOC100184081 PTHR21547:SF0 CLUSTERIN ASSOCIATED PROTEIN 1 CLUSTERIN-ASSOCIATED PROTEIN 1 organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cell projection organization#GO:0030030;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031 microtubule organizing center#GO:0005815;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intraciliary transport particle B#GO:0030992;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cytoskeleton#GO:0005856;cilium#GO:0005929;intraciliary transport particle#GO:0030990 CIOIN|Ensembl=ENSCING00000002937.3|UniProtKB=F7BIJ9 F7BIJ9 PTHR12864:SF54 RAN BINDING PROTEIN 9-RELATED SPRY DOMAIN-CONTAINING PROTEIN 3 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000007537.3|UniProtKB=Q8T894 Q8T894 DLC PTHR21255:SF65 T-COMPLEX-ASSOCIATED-TESTIS-EXPRESSED 1/ DYNEIN LIGHT CHAIN TCTEX1 DOMAIN-CONTAINING PROTEIN 2 protein binding#GO:0005515;binding#GO:0005488 microtubule-based movement#GO:0007018;cellular process#GO:0009987;microtubule-based process#GO:0007017 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;microtubule cytoskeleton#GO:0015630;dynein complex#GO:0030286;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic dynein complex#GO:0005868;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;microtubule or microtubule-binding cytoskeletal protein#PC00157 CIOIN|Ensembl=ENSCING00000007300.3|UniProtKB=F6YJQ7 F6YJQ7 LOC100175707 PTHR11699:SF228 ALDEHYDE DEHYDROGENASE-RELATED 4-TRIMETHYLAMINOBUTYRALDEHYDE DEHYDROGENASE oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 dehydrogenase#PC00092;oxidoreductase#PC00176 5-Hydroxytryptamine degredation#P04372>Aldehyde Dehydrogenase#P04402 CIOIN|Ensembl=ENSCING00000020086.1|UniProtKB=H2XLP3 H2XLP3 LOC100179683 PTHR10410:SF5 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 -RELATED 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 14 ubiquitin-like protein peptidase activity#GO:0019783;proteasome binding#GO:0070628;metallopeptidase activity#GO:0008237;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;protein-containing complex binding#GO:0044877;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;protein modification by small protein removal#GO:0070646;proteolysis#GO:0006508;protein deubiquitination#GO:0016579;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 peptidase complex#GO:1905368;proteasome accessory complex#GO:0022624;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;proteasome regulatory particle#GO:0005838;catalytic complex#GO:1902494;proteasome regulatory particle, lid subcomplex#GO:0008541;proteasome complex#GO:0000502;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;endopeptidase complex#GO:1905369;membrane-bounded organelle#GO:0043227 translation initiation factor#PC00224;translation factor#PC00223 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489;Cell cycle#P00013>Proteasome#P00480 CIOIN|Ensembl=ENSCING00000020926.1|UniProtKB=H2Y3U2 H2Y3U2 PTHR31435:SF9 PROTEIN NATD1 PROTEIN NATD1 CIOIN|Ensembl=ENSCING00000018191.1|UniProtKB=H2Y0Q6 H2Y0Q6 PTHR10352:SF0 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT G EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT G translation initiation factor#PC00224;translation factor#PC00223 CIOIN|Ensembl=ENSCING00000004163.3|UniProtKB=F7BQ97 F7BQ97 PTHR23050:SF485 CALCIUM BINDING PROTEIN RE52086P cation binding#GO:0043169;small molecule binding#GO:0036094;molecular function regulator activity#GO:0098772;binding#GO:0005488;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;enzyme regulator activity#GO:0030234 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 calmodulin-related#PC00061 CIOIN|Ensembl=ENSCING00000015069.2|UniProtKB=F6S7L1 F6S7L1 PTHR23113:SF312 GUANINE NUCLEOTIDE EXCHANGE FACTOR RAL GUANINE NUCLEOTIDE DISSOCIATION STIMULATOR-LIKE, ISOFORM E nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;small GTPase-mediated signal transduction#GO:0007264;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;Ras protein signal transduction#GO:0007265;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 CIOIN|Ensembl=ENSCING00000000988.3|UniProtKB=H2XW33 H2XW33 LOC100187353 PTHR15967:SF0 E2F-ASSOCIATED PHOSPHOPROTEIN E2F-ASSOCIATED PHOSPHOPROTEIN membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000005541.3|UniProtKB=F6XEV8 F6XEV8 LOC100184516 PTHR45688:SF13 FAMILY NOT NAMED ALANINE--GLYOXYLATE AMINOTRANSFERASE 2-LIKE cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 Pyruvate metabolism#P02772>Aminotransefrase#P03134 CIOIN|Ensembl=ENSCING00000013948.2|UniProtKB=F6RQ77 F6RQ77 PTHR11929:SF145 ALPHA- 1,3 -FUCOSYLTRANSFERASE ALPHA-(1,3)-FUCOSYLTRANSFERASE FUT-1 transferase activity#GO:0016740;fucosyltransferase activity#GO:0008417;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 glycosylation#GO:0070085;metabolic process#GO:0008152 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000015355.2|UniProtKB=F6QE09 F6QE09 PTHR11711:SF21 ADP RIBOSYLATION FACTOR-RELATED ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 6 carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167 cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;cilium assembly#GO:0060271;cell projection organization#GO:0030030;macromolecule localization#GO:0033036;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;cell projection assembly#GO:0030031;protein localization#GO:0008104;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;protein localization to cilium#GO:0061512;establishment of localization#GO:0051234;organelle organization#GO:0006996;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;protein localization to organelle#GO:0033365;plasma membrane bounded cell projection assembly#GO:0120031 axoneme#GO:0005930;cytoplasmic region#GO:0099568;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;plasma membrane bounded cell projection cytoplasm#GO:0032838;membrane-bounded organelle#GO:0043227;ciliary plasm#GO:0097014;cytoskeleton#GO:0005856;cell projection#GO:0042995;cilium#GO:0005929 G-protein#PC00020 CIOIN|Ensembl=ENSCING00000005572.3|UniProtKB=F6URN5 F6URN5 PTHR24028:SF328 CADHERIN-87A CADHERIN-3 cell adhesion#GO:0007155;cellular process#GO:0009987 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cell adhesion molecule#PC00069;cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 CIOIN|Ensembl=ENSCING00000009296.3|UniProtKB=F7B9Q3 F7B9Q3 PTHR10672:SF3 ADDUCIN PROTEIN HU-LI TAI SHAO cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-motor actin binding protein#PC00165 CIOIN|Ensembl=ENSCING00000003944.3|UniProtKB=F6ZKW1 F6ZKW1 PTHR24071:SF0 RAN GTPASE GTP-BINDING NUCLEAR PROTEIN RAN GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824 cellular component biogenesis#GO:0044085;ribosomal subunit export from nucleus#GO:0000054;cellular localization#GO:0051641;organelle localization#GO:0051640;macromolecule localization#GO:0033036;transport#GO:0006810;protein localization to nucleus#GO:0034504;nitrogen compound transport#GO:0071705;establishment of protein localization to organelle#GO:0072594;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;protein import into nucleus#GO:0006606;cellular macromolecule localization#GO:0070727;nuclear export#GO:0051168;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;ribonucleoprotein complex biogenesis#GO:0022613;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;ribosome biogenesis#GO:0042254;intracellular transport#GO:0046907;protein localization to organelle#GO:0033365;establishment of organelle localization#GO:0051656;nuclear transport#GO:0051169;protein-containing complex localization#GO:0031503;import into nucleus#GO:0051170 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 small GTPase#PC00208;G-protein#PC00020 CIOIN|Ensembl=ENSCING00000007326.3|UniProtKB=F6YK29 F6YK29 LOC100184967 PTHR11815:SF10 SUCCINYL-COA SYNTHETASE BETA CHAIN SUCCINATE--COA LIGASE [GDP-FORMING] SUBUNIT BETA, MITOCHONDRIAL ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877 cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;nucleobase-containing compound metabolic process#GO:0006139;energy derivation by oxidation of organic compounds#GO:0015980;phosphorus metabolic process#GO:0006793;tricarboxylic acid cycle#GO:0006099;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;amide metabolic process#GO:0043603;purine nucleotide metabolic process#GO:0006163;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;heterocycle metabolic process#GO:0046483;cellular respiration#GO:0045333;aerobic respiration#GO:0009060;acyl-CoA metabolic process#GO:0006637;generation of precursor metabolites and energy#GO:0006091;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;ribonucleotide metabolic process#GO:0009259;primary metabolic process#GO:0044238;purine ribonucleotide metabolic process#GO:0009150;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622 ligase#PC00142;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000010731.3|UniProtKB=F6ZE10 F6ZE10 PTHR18952:SF278 CARBONIC ANHYDRASE CARBONIC ANHYDRASE carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829;hydro-lyase activity#GO:0016836;catalytic activity#GO:0003824 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 dehydratase#PC00091;lyase#PC00144 CIOIN|Ensembl=ENSCING00000002943.3|UniProtKB=F6R8W1 F6R8W1 PTHR24248:SF174 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR TYRAMINE_OCTOPAMINE RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 CIOIN|Ensembl=ENSCING00000024001.1|UniProtKB=H2XR57 H2XR57 PTHR24372:SF77 GLYCOPROTEIN HORMONE RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 response to organic substance#GO:0010033;positive regulation of adenylate cyclase activity#GO:0045762;regulation of lyase activity#GO:0051339;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;cellular response to stimulus#GO:0051716;regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;cellular response to endogenous stimulus#GO:0071495;cellular response to chemical stimulus#GO:0070887;positive regulation of catalytic activity#GO:0043085;cellular response to organic substance#GO:0071310;regulation of cyclase activity#GO:0031279;positive regulation of molecular function#GO:0044093;cell communication#GO:0007154;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;positive regulation of cyclase activity#GO:0031281;hormone-mediated signaling pathway#GO:0009755;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to endogenous stimulus#GO:0009719;response to hormone#GO:0009725;cellular response to hormone stimulus#GO:0032870;response to chemical#GO:0042221;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of lyase activity#GO:0051349;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 CIOIN|Ensembl=ENSCING00000020282.1|UniProtKB=H2XMX1 H2XMX1 PTHR19282:SF431 TETRASPANIN TETRASPANIN 26A, ISOFORM B-RELATED cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000006336.3|UniProtKB=F6PSM8 F6PSM8 PTHR45817:SF4 LYSYL OXIDASE-LIKE-RELATED LYSYL OXIDASE-LIKE-RELATED catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 oxidase#PC00175;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000016168.2|UniProtKB=F6VQC2 F6VQC2 LOC108949270 PTHR12356:SF19 NUCLEAR MOVEMENT PROTEIN NUDC NUDC DOMAIN-CONTAINING PROTEIN 3 protein binding#GO:0005515;unfolded protein binding#GO:0051082;binding#GO:0005488 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein folding#GO:0006457;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;microtubule or microtubule-binding cytoskeletal protein#PC00157 CIOIN|Ensembl=ENSCING00000007725.3|UniProtKB=F6ZIS0 F6ZIS0 PTHR23278:SF19 SIDESTEP PROTEIN OBSCURIN immunoglobulin superfamily cell adhesion molecule#PC00125 CIOIN|Ensembl=ENSCING00000019220.1|UniProtKB=H2XKH5 H2XKH5 PTHR20905:SF1 N-ACETYLTRANSFERASE-RELATED AT07410P-RELATED acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;N-acetyltransferase activity#GO:0008080;acyltransferase activity#GO:0016746;acetyltransferase activity#GO:0016407;catalytic activity#GO:0003824;N-acyltransferase activity#GO:0016410 acetyltransferase#PC00038 CIOIN|Ensembl=ENSCING00000007693.3|UniProtKB=F6SJ40 F6SJ40 PTHR43557:SF2 APOPTOSIS-INDUCING FACTOR 1 RIESKE DOMAIN-CONTAINING PROTEIN-RELATED oxidoreductase activity, acting on NAD(P)H#GO:0016651;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000002147.3|UniProtKB=H2Y1I7 H2Y1I7 PTHR13371:SF0 GLYCINE-, GLUTAMATE-, THIENYLCYCLOHEXYLPIPERIDINE-BINDING PROTEIN CENTROSOMAL PROTEIN OF 104 KDA membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;cilium#GO:0005929;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025 CIOIN|Ensembl=ENSCING00000013582.2|UniProtKB=F6XNC0 F6XNC0 PTHR23220:SF122 INTEGRIN ALPHA INTEGRIN ALPHA-PS1 cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;integrin binding#GO:0005178;binding#GO:0005488;signaling receptor binding#GO:0005102 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cell adhesion mediated by integrin#GO:0033627;cell-cell adhesion#GO:0098609;cell communication#GO:0007154;cell adhesion#GO:0007155;cell-substrate adhesion#GO:0031589;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cell-matrix adhesion#GO:0007160;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;integrin-mediated signaling pathway#GO:0007229;biological regulation#GO:0065007;signaling#GO:0023052 receptor complex#GO:0043235;membrane protein complex#GO:0098796;external side of plasma membrane#GO:0009897;cell surface#GO:0009986;protein-containing complex#GO:0032991;plasma membrane signaling receptor complex#GO:0098802;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 cell adhesion molecule#PC00069;integrin#PC00126 Integrin signalling pathway#P00034>Integrin alpha#P00941 CIOIN|Ensembl=ENSCING00000008411.3|UniProtKB=F6VUE2 F6VUE2 LOC100182819 PTHR12439:SF42 PLACENTAL PROTEIN 11-RELATED ENDORIBONUCLEASE-RELATED catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a nucleic acid#GO:0140640;endonuclease activity#GO:0004519;RNA nuclease activity#GO:0004540;RNA endonuclease activity#GO:0004521 CIOIN|Ensembl=ENSCING00000004022.3|UniProtKB=F6SKI3 F6SKI3 PTHR10110:SF187 SODIUM/HYDROGEN EXCHANGER SODIUM_HYDROGEN EXCHANGER secondary active transmembrane transporter activity#GO:0015291;inorganic molecular entity transmembrane transporter activity#GO:0015318;antiporter activity#GO:0015297;transmembrane transporter activity#GO:0022857;potassium ion transmembrane transporter activity#GO:0015079;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;proton transmembrane transporter activity#GO:0015078;metal cation:proton antiporter activity#GO:0051139;active monoatomic ion transmembrane transporter activity#GO:0022853;monoatomic cation transmembrane transporter activity#GO:0008324;monoatomic ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;inorganic cation transmembrane transporter activity#GO:0022890;transporter activity#GO:0005215 regulation of intracellular pH#GO:0051453;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;homeostatic process#GO:0042592;inorganic ion transmembrane transport#GO:0098660;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;cellular process#GO:0009987;intracellular chemical homeostasis#GO:0055082;monoatomic ion homeostasis#GO:0050801;localization#GO:0051179;regulation of pH#GO:0006885;import across plasma membrane#GO:0098739;sodium ion transport#GO:0006814;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;intracellular monoatomic cation homeostasis#GO:0030003;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;monoatomic cation transport#GO:0006812;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion transport#GO:0006811;regulation of cellular pH#GO:0030641;import into cell#GO:0098657;monoatomic cation transmembrane transport#GO:0098655;sodium ion transmembrane transport#GO:0035725;potassium ion transport#GO:0006813 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000018513.1|UniProtKB=H2XNS6 H2XNS6 PTHR21676:SF1 PROTEIN STUM PROTEIN STUM HOMOLOG CIOIN|Ensembl=ENSCING00000022971.1|UniProtKB=H2XMF0 H2XMF0 LOC100176514 PTHR11075:SF54 PEPTIDE CHAIN RELEASE FACTOR LARGE RIBOSOMAL SUBUNIT PROTEIN ML62 catalytic activity, acting on RNA#GO:0140098;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;translation regulator activity#GO:0045182;nucleic acid binding#GO:0003676;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity#GO:0016787;translation regulator activity, nucleic acid binding#GO:0090079;translation factor activity, RNA binding#GO:0008135 translation release factor#PC00225;translation factor#PC00223;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000003067.3|UniProtKB=F6PPI4 F6PPI4 LOC100181600 PTHR43340:SF1 HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE cation binding#GO:0043169;transferase activity#GO:0016740;magnesium ion binding#GO:0000287;small molecule binding#GO:0036094;glycosyltransferase activity#GO:0016757;binding#GO:0005488;catalytic activity#GO:0003824;metal ion binding#GO:0046872;ion binding#GO:0043167;pentosyltransferase activity#GO:0016763 cellular aromatic compound metabolic process#GO:0006725;purine ribonucleoside monophosphate metabolic process#GO:0009167;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;nucleobase metabolic process#GO:0009112;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;nucleoside monophosphate metabolic process#GO:0009123;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;IMP metabolic process#GO:0046040;heterocycle metabolic process#GO:0046483;purine nucleoside monophosphate metabolic process#GO:0009126;purine nucleobase metabolic process#GO:0006144;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;ribose phosphate biosynthetic process#GO:0046390;ribonucleoside monophosphate metabolic process#GO:0009161;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;IMP biosynthetic process#GO:0006188;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 Adenine and hypoxanthine salvage pathway#P02723>Hypoxanthine phosphoribosyl transferase#P02804;Salvage pyrimidine ribonucleotides#P02775>Uracil phosphoribosyl transferase#P03151;Xanthine and guanine salvage pathway#P02788>Guanine phosphoribosyl transferase#P03245;Xanthine and guanine salvage pathway#P02788>Xanthine phosphoribosyl transferase#P03247 CIOIN|Ensembl=ENSCING00000020338.1|UniProtKB=H2Y1U3 H2Y1U3 PTHR11042:SF136 EUKARYOTIC TRANSLATION INITIATION FACTOR 2-ALPHA KINASE EIF2-ALPHA KINASE -RELATED EIF-2-ALPHA KINASE GCN2 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;phosphorylation#GO:0016310;protein phosphorylation#GO:0006468;cellular process#GO:0009987;protein metabolic process#GO:0019538;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000012115.2|UniProtKB=F6V8Z4 F6V8Z4 PTHR28457:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 189 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 119 CIOIN|Ensembl=ENSCING00000018194.1|UniProtKB=F6YHT4 F6YHT4 PTHR23077:SF171 AAA-FAMILY ATPASE NUCLEAR VALOSIN-CONTAINING PROTEIN-LIKE pyrophosphatase activity#GO:0016462;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;ATP hydrolysis activity#GO:0016887 primary active transporter#PC00068;transporter#PC00227 CIOIN|Ensembl=ENSCING00000009151.3|UniProtKB=F7BB64 F7BB64 PTHR12461:SF42 HYPOXIA-INDUCIBLE FACTOR 1 ALPHA INHIBITOR-RELATED JMJC DOMAIN-CONTAINING PROTEIN protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000005526.3|UniProtKB=F6YP84 F6YP84 PTHR12308:SF84 ANOCTAMIN ANOCTAMIN inorganic molecular entity transmembrane transporter activity#GO:0015318;chloride channel activity#GO:0005254;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;chloride transmembrane transporter activity#GO:0015108;monoatomic anion transmembrane transporter activity#GO:0008509;inorganic anion transmembrane transporter activity#GO:0015103;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267;monoatomic ion channel activity#GO:0005216 localization#GO:0051179;inorganic anion transmembrane transport#GO:0098661;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic anion transmembrane transport#GO:0098656;monoatomic ion transmembrane transport#GO:0034220;monoatomic anion transport#GO:0006820;transport#GO:0006810;chloride transport#GO:0006821;chloride transmembrane transport#GO:1902476;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 CIOIN|Ensembl=ENSCING00000008754.3|UniProtKB=F6T0L0 F6T0L0 LOC100181424 PTHR23324:SF66 SEC14 RELATED PROTEIN PROTEIN REAL-TIME cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 transfer/carrier protein#PC00219 CIOIN|Ensembl=ENSCING00000018361.1|UniProtKB=H2XRN3 H2XRN3 PTHR22792:SF140 LUPUS LA PROTEIN-RELATED ACHILLES, ISOFORM A nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000011449.2|UniProtKB=F7ACN4 F7ACN4 PTHR24253:SF178 TRANSMEMBRANE PROTEASE SERINE TRANSMEMBRANE PROTEASE SERINE 12 serine protease#PC00203;protease#PC00190 CIOIN|Ensembl=ENSCING00000006844.3|UniProtKB=F6ZXN3 F6ZXN3 LOC100177683 PTHR12869:SF0 SMALL SEVEN TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN BOS COMPLEX SUBUNIT TMEM147 CIOIN|Ensembl=ENSCING00000007410.3|UniProtKB=F7B875 F7B875 kif3b PTHR24115:SF789 KINESIN-RELATED KINESIN-LIKE PROTEIN KLP68D pyrophosphatase activity#GO:0016462;cytoskeletal protein binding#GO:0008092;microtubule motor activity#GO:0003777;tubulin binding#GO:0015631;ATP-dependent activity#GO:0140657;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;cytoskeletal motor activity#GO:0003774;microtubule binding#GO:0008017;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;ribonucleoside triphosphate phosphatase activity#GO:0017111;ATP hydrolysis activity#GO:0016887 microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;microtubule associated complex#GO:0005875;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 CIOIN|Ensembl=ENSCING00000005236.3|UniProtKB=F6YHE2 F6YHE2 LOC100180079 PTHR24119:SF0 ACYL-COA-BINDING DOMAIN-CONTAINING PROTEIN 6 ACYL-COA-BINDING DOMAIN-CONTAINING PROTEIN 6 nucleotide binding#GO:0000166;carbohydrate derivative binding#GO:0097367;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;amide binding#GO:0033218;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;lipid binding#GO:0008289;ion binding#GO:0043167;anion binding#GO:0043168 CIOIN|Ensembl=ENSCING00000005595.3|UniProtKB=A0A1W2WG08 A0A1W2WG08 PTHR11953:SF1 EXOSOME COMPLEX COMPONENT EXOSOME COMPLEX COMPONENT RRP46 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;heterocycle catabolic process#GO:0046700;RNA metabolic process#GO:0016070;RNA processing#GO:0006396;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;cellular nitrogen compound catabolic process#GO:0044270;regulation of biological process#GO:0050789;ncRNA metabolic process#GO:0034660;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;mRNA catabolic process#GO:0006402;snRNA 3'-end processing#GO:0034472;catabolic process#GO:0009056;snRNA processing#GO:0016180;RNA catabolic process#GO:0006401;regulation of macromolecule biosynthetic process#GO:0010556;organic substance catabolic process#GO:1901575;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;snRNA metabolic process#GO:0016073;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;negative regulation of metabolic process#GO:0009892;nuclear-transcribed mRNA catabolic process#GO:0000956;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;aromatic compound catabolic process#GO:0019439;regulation of macromolecule metabolic process#GO:0060255;rRNA metabolic process#GO:0016072;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;nucleobase-containing compound catabolic process#GO:0034655;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;exosome (RNase complex)#GO:0000178;nuclear protein-containing complex#GO:0140513 RNA metabolism protein#PC00031;exoribonuclease#PC00099 CIOIN|Ensembl=ENSCING00000008269.3|UniProtKB=F6QTX2 F6QTX2 PTHR15593:SF3 PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT PROTEIN DDB_G0292252-RELATED kinase modulator#PC00140 CIOIN|Ensembl=ENSCING00000003779.3|UniProtKB=F6TIM2 F6TIM2 LOC100183747 PTHR12755:SF6 CLEAVAGE/POLYADENYLATION FACTOR IA SUBUNIT CLP1P POLYRIBONUCLEOTIDE 5'-HYDROXYL-KINASE CLP1 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;tRNA processing#GO:0008033;RNA processing#GO:0006396;mRNA polyadenylation#GO:0006378;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;mRNA 3'-end processing#GO:0031124;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;tRNA splicing, via endonucleolytic cleavage and ligation#GO:0006388;mRNA processing#GO:0006397;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 mRNA polyadenylation factor#PC00146;RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000024241.1|UniProtKB=F6SRF9 F6SRF9 LOC100186294 PTHR12684:SF2 PUTATIVE PHOSPHOTRANSFERASE TRNA 2'-PHOSPHOTRANSFERASE 1 catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000012541.2|UniProtKB=F7AUE9 F7AUE9 LOC100185795 PTHR39947:SF1 IP19862P IP19862P CIOIN|Ensembl=ENSCING00000009470.3|UniProtKB=F7AF59 F7AF59 LOC100182304 PTHR12403:SF11 TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 2 TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 2-LIKE PROTEIN localization#GO:0051179;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;establishment of localization#GO:0051234;transport#GO:0006810;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;vesicle tethering complex#GO:0099023;TRAPP complex#GO:0030008;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150 CIOIN|Ensembl=ENSCING00000024316.1|UniProtKB=H2XXH7 H2XXH7 LOC100186313 PTHR14084:SF0 KYNURENINASE KYNURENINASE hydrolase activity#GO:0016787;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;heterocycle catabolic process#GO:0046700;biogenic amine metabolic process#GO:0006576;organonitrogen compound catabolic process#GO:1901565;cellular nitrogen compound catabolic process#GO:0044270;amino acid catabolic process#GO:0009063;organic cyclic compound metabolic process#GO:1901360;aromatic amino acid metabolic process#GO:0009072;nitrogen compound metabolic process#GO:0006807;alpha-amino acid metabolic process#GO:1901605;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248;heterocycle metabolic process#GO:0046483;amine metabolic process#GO:0009308;oxoacid metabolic process#GO:0043436;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;aromatic compound catabolic process#GO:0019439;organic cyclic compound catabolic process#GO:1901361;aromatic amino acid family catabolic process#GO:0009074;carboxylic acid metabolic process#GO:0019752;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000019411.1|UniProtKB=H2Y016 H2Y016 PTHR34400:SF4 FAMILY NOT NAMED MEMBRANE PROTEIN CIOIN|Ensembl=ENSCING00000006321.3|UniProtKB=F6Q427 F6Q427 PTHR14716:SF0 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 69 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 69 structural protein#PC00211 CIOIN|Ensembl=ENSCING00000019903.1|UniProtKB=H2XP72 H2XP72 LOC100177593 PTHR12170:SF3 MACROPHAGE ERYTHROBLAST ATTACHER-RELATED GH10162P transferase activity#GO:0016740;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000008585.3|UniProtKB=F6UDF7 F6UDF7 PTHR24180:SF45 CYCLIN-DEPENDENT KINASE INHIBITOR 2C-RELATED POLY [ADP-RIBOSE] POLYMERASE TANKYRASE kinase inhibitor#PC00139 CIOIN|Ensembl=ENSCING00000001967.3|UniProtKB=F6XDP4 F6XDP4 LOC100185896 PTHR11431:SF75 FERRITIN FERRITIN cation binding#GO:0043169;ferrous iron binding#GO:0008198;small molecule binding#GO:0036094;binding#GO:0005488;iron ion binding#GO:0005506;transition metal ion binding#GO:0046914;metal ion binding#GO:0046872;ion binding#GO:0043167 localization#GO:0051179;inorganic ion homeostasis#GO:0098771;cellular localization#GO:0051641;intracellular iron ion homeostasis#GO:0006879;maintenance of location#GO:0051235;maintenance of location in cell#GO:0051651;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;homeostatic process#GO:0042592;intracellular monoatomic ion homeostasis#GO:0006873;chemical homeostasis#GO:0048878;cellular process#GO:0009987;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;monoatomic ion homeostasis#GO:0050801 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 storage protein#PC00210 CIOIN|Ensembl=ENSCING00000006975.3|UniProtKB=F6SBG8 F6SBG8 PTHR24006:SF664 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE cysteine-type peptidase activity#GO:0008234;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;cysteine-type deubiquitinase activity#GO:0004843 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;protein modification by small protein removal#GO:0070646;protein deubiquitination#GO:0016579;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;post-translational protein modification#GO:0043687;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cysteine protease#PC00081;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000017001.2|UniProtKB=F6TN85 F6TN85 LOC100175128 PTHR19143:SF424 FIBRINOGEN/TENASCIN/ANGIOPOEITIN FIBRINOGEN C-TERMINAL DOMAIN-CONTAINING PROTEIN external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 CIOIN|Ensembl=ENSCING00000004671.3|UniProtKB=F6QSQ2 F6QSQ2 PTHR11616:SF289 SODIUM/CHLORIDE DEPENDENT TRANSPORTER TRANSPORTER secondary active monocarboxylate transmembrane transporter activity#GO:0015355;inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;organic acid:sodium symporter activity#GO:0005343;organic acid transmembrane transporter activity#GO:0005342;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;chloride transmembrane transporter activity#GO:0015108;organic anion transmembrane transporter activity#GO:0008514;monoatomic cation transmembrane transporter activity#GO:0008324;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;amino acid:sodium symporter activity#GO:0005283;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;metal ion transmembrane transporter activity#GO:0046873;active monoatomic ion transmembrane transporter activity#GO:0022853;monoatomic anion transmembrane transporter activity#GO:0008509;monocarboxylic acid transmembrane transporter activity#GO:0008028;amino acid transmembrane transporter activity#GO:0015171;inorganic anion transmembrane transporter activity#GO:0015103;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;organic anion transport#GO:0015711;amino acid transport#GO:0006865;organic acid transport#GO:0015849;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;localization#GO:0051179;organic substance transport#GO:0071702;sodium ion transport#GO:0006814;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;sodium ion transmembrane transport#GO:0035725 cell projection#GO:0042995;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 primary active transporter#PC00068;transporter#PC00227 CIOIN|Ensembl=ENSCING00000003421.3|UniProtKB=F6XKP0 F6XKP0 PTHR23073:SF7 26S PROTEASOME REGULATORY SUBUNIT 26S PROTEASOME REGULATORY SUBUNIT 6A ATP-dependent activity#GO:0140657 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 peptidase complex#GO:1905368;protein-containing complex#GO:0032991;proteasome accessory complex#GO:0022624;proteasome regulatory particle#GO:0005838;catalytic complex#GO:1902494;proteasome complex#GO:0000502;endopeptidase complex#GO:1905369;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 protease#PC00190;protein modifying enzyme#PC00260 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489 CIOIN|Ensembl=ENSCING00000014740.2|UniProtKB=F6W9P9 F6W9P9 PTHR46105:SF28 AGAP004733-PA ZINC FINGER PROTEIN 37-LIKE sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 CIOIN|Ensembl=ENSCING00000018326.1|UniProtKB=H2Y139 H2Y139 LOC100175682 PTHR17598:SF13 DNA POLYMERASE DELTA SUBUNIT 3 DNA POLYMERASE DELTA SUBUNIT 3 DNA-directed DNA polymerase activity#GO:0003887;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on DNA#GO:0140097;DNA polymerase activity#GO:0034061 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;response to radiation#GO:0009314;cellular nitrogen compound biosynthetic process#GO:0044271;DNA-templated DNA replication#GO:0006261;response to abiotic stimulus#GO:0009628;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular response to light stimulus#GO:0071482;nucleotide-excision repair#GO:0006289;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;response to light stimulus#GO:0009416;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;nucleobase-containing compound biosynthetic process#GO:0034654;response to UV#GO:0009411;DNA biosynthetic process#GO:0071897;DNA synthesis involved in DNA repair#GO:0000731;aromatic compound biosynthetic process#GO:0019438;DNA replication#GO:0006260;cellular response to stress#GO:0033554;DNA strand elongation involved in DNA replication#GO:0006271;DNA metabolic process#GO:0006259 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-DNA complex#GO:0032993;catalytic complex#GO:1902494;transferase complex#GO:1990234;replisome#GO:0030894;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622;DNA polymerase complex#GO:0042575;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nuclear replication fork#GO:0043596;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513;replication fork#GO:0005657 DNA metabolism protein#PC00009 CIOIN|Ensembl=ENSCING00000005522.3|UniProtKB=F6YP95 F6YP95 PTHR23117:SF18 GUANYLATE KINASE-RELATED LEUCINE-RICH REPEAT AND GUANYLATE KINASE DOMAIN-CONTAINING PROTEIN transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, phosphate group as acceptor#GO:0016776;catalytic activity#GO:0003824;kinase activity#GO:0016301 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 transferase#PC00220;kinase#PC00137;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000020704.1|UniProtKB=H2Y2W5 H2Y2W5 PTHR14002:SF54 ENDOGLIN/TGF-BETA RECEPTOR TYPE III ZONA PELLUCIDA SPERM-BINDING PROTEIN 2 transmembrane signal receptor#PC00197 CIOIN|Ensembl=ENSCING00000001245.3|UniProtKB=F7AEP2 F7AEP2 LOC100177880 PTHR13048:SF0 TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 3 TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT localization#GO:0051179;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;establishment of localization#GO:0051234;intra-Golgi vesicle-mediated transport#GO:0006891;transport#GO:0006810;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193 bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;vesicle tethering complex#GO:0099023;TRAPP complex#GO:0030008;Golgi apparatus#GO:0005794;cytosol#GO:0005829;organelle membrane#GO:0031090;intracellular protein-containing complex#GO:0140535;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cis-Golgi network#GO:0005801;membrane-bounded organelle#GO:0043227 CIOIN|Ensembl=ENSCING00000006517.3|UniProtKB=F6PV21 F6PV21 LOC100186210 PTHR13269:SF6 NUCLEOPORIN NDC1 NUCLEOPORIN NDC1 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 nucleus organization#GO:0006997;cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;cellular process#GO:0009987;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933 envelope#GO:0031975;nuclear pore#GO:0005643;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear envelope#GO:0005635;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000018570.1|UniProtKB=H2Y0P9 H2Y0P9 PTHR36981:SF9 ZGC:195170 NANOR-RELATED CIOIN|Ensembl=ENSCING00000012770.2|UniProtKB=L7N0U6 L7N0U6 LOC100185689 PTHR43296:SF2 PEROXISOMAL 2,4-DIENOYL-COA REDUCTASE PEROXISOMAL 2,4-DIENOYL-COA REDUCTASE [(3E)-ENOYL-COA-PRODUCING] oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor#GO:0016628 lipid metabolic process#GO:0006629;oxoacid metabolic process#GO:0043436;fatty acid metabolic process#GO:0006631;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular lipid metabolic process#GO:0044255;organic acid metabolic process#GO:0006082;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;peroxisome#GO:0005777;microbody#GO:0042579;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 reductase#PC00198;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000005238.3|UniProtKB=F6XUX1 F6XUX1 PTHR11825:SF44 SUBGROUP IIII AMINOTRANSFERASE BRANCHED-CHAIN-AMINO-ACID AMINOTRANSFERASE transaminase#PC00216 Alanine biosynthesis#P02724>Branched chain amino acid aminotransferase#P02815;Leucine biosynthesis#P02749>Branched chain amino acid aminotransferase#P03000;Valine biosynthesis#P02785>Branched chain amino acid aminotransferase#P03215;Isoleucine biosynthesis#P02748>Branched chain amino acid aminotransferase#P02994 CIOIN|Ensembl=ENSCING00000005609.3|UniProtKB=F7ATT5 F7ATT5 LOC100185558 PTHR13594:SF1 CENTRIOLAR COILED-COIL PROTEIN OF 110 KDA CENTRIOLAR COILED-COIL PROTEIN OF 110 KDA CIOIN|Ensembl=ENSCING00000012206.2|UniProtKB=F7BPJ6 F7BPJ6 PTHR10896:SF65 GALACTOSYLGALACTOSYLXYLOSYLPROTEIN 3-BETA-GLUCURONOSYLTRANSFERASE BETA-1,3-GLUCURONYLTRANSFERASE GALACTOSYLGALACTOSYLXYLOSYLPROTEIN 3-BETA-GLUCURONOSYLTRANSFERASE 3 carbohydrate metabolic process#GO:0005975;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;primary metabolic process#GO:0044238 cytoplasm#GO:0005737;bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;Golgi membrane#GO:0000139;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111 CIOIN|Ensembl=ENSCING00000006144.3|UniProtKB=F6V3B4 F6V3B4 PTHR10361:SF19 SODIUM-BILE ACID COTRANSPORTER ILEAL SODIUM_BILE ACID COTRANSPORTER secondary active monocarboxylate transmembrane transporter activity#GO:0015355;inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;organic acid:sodium symporter activity#GO:0005343;organic acid transmembrane transporter activity#GO:0005342;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;bile acid transmembrane transporter activity#GO:0015125;organic anion transmembrane transporter activity#GO:0008514;monoatomic cation transmembrane transporter activity#GO:0008324;active transmembrane transporter activity#GO:0022804;lipid transporter activity#GO:0005319;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;metal ion transmembrane transporter activity#GO:0046873;active monoatomic ion transmembrane transporter activity#GO:0022853;monocarboxylic acid transmembrane transporter activity#GO:0008028;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294 localization#GO:0051179;organic hydroxy compound transport#GO:0015850;organic substance transport#GO:0071702;monocarboxylic acid transport#GO:0015718;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;organic anion transport#GO:0015711;organic acid transport#GO:0015849;transport#GO:0006810;carboxylic acid transport#GO:0046942;lipid localization#GO:0010876;bile acid and bile salt transport#GO:0015721;lipid transport#GO:0006869 primary active transporter#PC00068;transporter#PC00227 CIOIN|Ensembl=ENSCING00000008739.2|UniProtKB=F6TMF3 F6TMF3 PTHR19269:SF45 TROPOMYOSIN TROPOMYOSIN-1, ISOFORMS 33_34 cytoskeletal protein#PC00085;actin binding motor protein#PC00040 CIOIN|Ensembl=ENSCING00000009665.3|UniProtKB=F6W8I3 F6W8I3 LOC100187210 PTHR19375:SF395 HEAT SHOCK PROTEIN 70KDA HEAT SHOCK 70 KDA PROTEIN ISOFORM X1-RELATED cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 Hsp70 family chaperone#PC00027 Parkinson disease#P00049>Hsp70#P01208;Apoptosis signaling pathway#P00006>HSP70#P00321 CIOIN|Ensembl=ENSCING00000020909.1|UniProtKB=H2XKN0 H2XKN0 LOC100175302 PTHR43020:SF2 CDK5 REGULATORY SUBUNIT-ASSOCIATED PROTEIN 1 MITOCHONDRIAL TRNA METHYLTHIOTRANSFERASE CDK5RAP1 transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;small molecule binding#GO:0036094;iron-sulfur cluster binding#GO:0051536;binding#GO:0005488;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA modification#GO:0009451;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;tRNA modification#GO:0006400;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 CIOIN|Ensembl=ENSCING00000012916.2|UniProtKB=F6RMN1 F6RMN1 PTHR24329:SF543 HOMEOBOX PROTEIN ARISTALESS FI01017P-RELATED sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 CIOIN|Ensembl=ENSCING00000008947.3|UniProtKB=F6Q5V5 F6Q5V5 PTHR11915:SF447 SPECTRIN/FILAMIN RELATED CYTOSKELETAL PROTEIN SPECTRIN BETA CHAIN cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actin filament-based process#GO:0030029;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987;organelle organization#GO:0006996 cortical cytoskeleton#GO:0030863;cell junction#GO:0030054;cellular anatomical entity#GO:0110165;cell cortex#GO:0005938;cell periphery#GO:0071944;cortical actin cytoskeleton#GO:0030864;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cytoskeleton#GO:0005856;cell projection#GO:0042995;plasma membrane#GO:0005886 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 CIOIN|Ensembl=ENSCING00000007492.3|UniProtKB=F6XW18 F6XW18 LOC100180213 PTHR46545:SF1 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 51 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 51 CIOIN|Ensembl=ENSCING00000013918.2|UniProtKB=F6PUV1 F6PUV1 LOC100179365 PTHR22906:SF46 PROPERDIN HEMICENTIN-1-LIKE CIOIN|Ensembl=ENSCING00000024391.1|UniProtKB=H2XTN4 H2XTN4 PTHR42909:SF1 ZGC:136858 CARBOHYDRATE KINASE PFKB DOMAIN-CONTAINING PROTEIN hydrolase activity#GO:0016787;carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydro-lyase activity#GO:0016836;catalytic activity#GO:0003824 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000024121.1|UniProtKB=H2XNS7 H2XNS7 LOC100185994 PTHR13832:SF818 PROTEIN PHOSPHATASE 2C SD03870P negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;protein modification process#GO:0036211;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;negative regulation of protein phosphorylation#GO:0001933;negative regulation of protein modification process#GO:0031400;regulation of molecular function#GO:0065009;nitrogen compound metabolic process#GO:0006807;negative regulation of protein kinase activity#GO:0006469;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;regulation of kinase activity#GO:0043549;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of protein kinase activity#GO:0045859;macromolecule metabolic process#GO:0043170;negative regulation of phosphorus metabolic process#GO:0010563;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein dephosphorylation#GO:0006470;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;cellular process#GO:0009987;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;regulation of macromolecule metabolic process#GO:0060255;negative regulation of phosphorylation#GO:0042326;regulation of cellular process#GO:0050794;regulation of protein phosphorylation#GO:0001932;negative regulation of macromolecule metabolic process#GO:0010605;dephosphorylation#GO:0016311;biological regulation#GO:0065007;negative regulation of phosphate metabolic process#GO:0045936;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;negative regulation of catalytic activity#GO:0043086;regulation of metabolic process#GO:0019222;negative regulation of molecular function#GO:0044092;regulation of cellular metabolic process#GO:0031323 protein phosphatase#PC00195;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000025106.1|UniProtKB=H2XQU3 H2XQU3 PTHR13546:SF15 RE60986P CCDC85 CIOIN|Ensembl=ENSCING00000000714.3|UniProtKB=F6Q5I2 F6Q5I2 PTHR46685:SF1 28S RIBOSOMAL PROTEIN S15, MITOCHONDRIAL SMALL RIBOSOMAL SUBUNIT PROTEIN US15M structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;structural molecule activity#GO:0005198;binding#GO:0005488;organic cyclic compound binding#GO:0097159 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;mitochondrial gene expression#GO:0140053;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;mitochondrial translation#GO:0032543;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;mitochondrial ribosome#GO:0005761;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;ribosomal subunit#GO:0044391;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;organellar ribosome#GO:0000313;protein-containing complex#GO:0032991;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;small ribosomal subunit#GO:0015935;ribosome#GO:0005840;mitochondrial small ribosomal subunit#GO:0005763;mitochondrial protein-containing complex#GO:0098798 ribosomal protein#PC00202;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000006246.3|UniProtKB=Q4H2I7 Q4H2I7 Ci-ZF(C2H2)-28 PTHR23215:SF0 ZINC FINGER PROTEIN 207 BUB3-INTERACTING AND GLEBS MOTIF-CONTAINING PROTEIN ZNF207 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA metabolism protein#PC00009 CIOIN|Ensembl=ENSCING00000018849.1|UniProtKB=H2XLA1 H2XLA1 PTHR31046:SF1 TRANSMEMBRANE PROTEIN 121 TRANSMEMBRANE PROTEIN 121 CIOIN|Ensembl=ENSCING00000000950.3|UniProtKB=H2XPP2 H2XPP2 LOC100178292 PTHR15881:SF2 MARGINAL ZONE B- AND B1-CELL-SPECIFIC PROTEIN MARGINAL ZONE B- AND B1-CELL-SPECIFIC PROTEIN regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;regulation of leukocyte activation#GO:0002694;regulation of multicellular organismal process#GO:0051239;regulation of mononuclear cell proliferation#GO:0032944;regulation of cell population proliferation#GO:0042127;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of lymphocyte proliferation#GO:0050670;regulation of immune system process#GO:0002682;regulation of leukocyte proliferation#GO:0070663;regulation of lymphocyte activation#GO:0051249;regulation of B cell proliferation#GO:0030888 cytoplasm#GO:0005737;endoplasmic reticulum protein-containing complex#GO:0140534;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;extracellular region#GO:0005576;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000006745.3|UniProtKB=F6Y0Q5 F6Y0Q5 LOC100183344 PTHR12771:SF2 ENGULFMENT AND CELL MOTILITY ELMO DOMAIN-CONTAINING PROTEIN 3 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000007235.3|UniProtKB=F6VKA0 F6VKA0 LOC100186033 PTHR11851:SF49 METALLOPROTEASE MITOCHONDRIAL-PROCESSING PEPTIDASE SUBUNIT ALPHA metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000004753.3|UniProtKB=Q4H3R5 Q4H3R5 Ci-CREB_ATF-c PTHR45879:SF3 CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN B CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN B sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667 DNA-binding transcription factor#PC00218;basic leucine zipper transcription factor#PC00056 Transcription regulation by bZIP transcription factor#P00055>CREB#P01383;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>CREB#P00713 CIOIN|Ensembl=ENSCING00000013260.2|UniProtKB=F6SFH4 F6SFH4 PTHR45834:SF3 RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 9-RELATED RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 3, ISOFORM L nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;guanyl-nucleotide exchange factor activity#GO:0005085 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 CIOIN|Ensembl=ENSCING00000020999.1|UniProtKB=H2XY67 H2XY67 PTHR24243:SF234 G-PROTEIN COUPLED RECEPTOR GROWTH HORMONE SECRETAGOGUE RECEPTOR TYPE 1-LIKE signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 CIOIN|Ensembl=ENSCING00000005651.3|UniProtKB=F6Y206 F6Y206 PTHR28592:SF1 ARMADILLO REPEAT-CONTAINING PROTEIN 1 ARMADILLO REPEAT-CONTAINING PROTEIN 1 CIOIN|Ensembl=ENSCING00000021878.1|UniProtKB=H2Y1L9 H2Y1L9 PTHR31658:SF0 CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 1 CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 1 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000022490.1|UniProtKB=H2XNK3 H2XNK3 PTHR18916:SF93 DYNACTIN 1-RELATED MICROTUBULE-BINDING RESTIN HOMOLOG chaperone#PC00072 CIOIN|Ensembl=ENSCING00000003983.3|UniProtKB=F6WKL0 F6WKL0 LOC100175009 PTHR14102:SF11 PAR-6-RELATED LD29223P cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;microtubule cytoskeleton organization#GO:0000226;centrosome cycle#GO:0007098;cell cycle process#GO:0022402;cell cycle#GO:0007049;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cellular process#GO:0009987;microtubule organizing center organization#GO:0031023 tight junction#PC00214 CIOIN|Ensembl=ENSCING00000012891.2|UniProtKB=A0A1W2WJU7 A0A1W2WJU7 LOC100177281 PTHR14002:SF20 ENDOGLIN/TGF-BETA RECEPTOR TYPE III ZONA PELLUCIDA-LIKE DOMAIN-CONTAINING PROTEIN 1 transmembrane signal receptor#PC00197 CIOIN|Ensembl=ENSCING00000004311.3|UniProtKB=F6SHN0 F6SHN0 LOC100178428 PTHR22600:SF21 BETA-HEXOSAMINIDASE BETA-HEXOSAMINIDASE A hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 glycosaminoglycan metabolic process#GO:0030203;carbohydrate derivative metabolic process#GO:1901135;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;aminoglycan metabolic process#GO:0006022;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;membrane#GO:0016020 glycosidase#PC00110;metabolite interconversion enzyme#PC00262;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000008812.3|UniProtKB=F6V2C0 F6V2C0 PTHR12709:SF5 DNA-DIRECTED RNA POLYMERASE II, III DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA43 cellular aromatic compound metabolic process#GO:0006725;DNA-templated transcription#GO:0006351;RNA metabolic process#GO:0016070;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;ncRNA metabolic process#GO:0034660;transcription by RNA polymerase I#GO:0006360;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;rRNA transcription#GO:0009303;nucleolar large rRNA transcription by RNA polymerase I#GO:0042790;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;transcription elongation by RNA polymerase I#GO:0006362;heterocycle metabolic process#GO:0046483;DNA-templated transcription elongation#GO:0006354;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;ncRNA transcription#GO:0098781;aromatic compound biosynthetic process#GO:0019438 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;DNA-directed RNA polymerase complex#GO:0000428;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular protein-containing complex#GO:0140535;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;RNA polymerase complex#GO:0030880;protein-containing complex#GO:0032991;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;RNA polymerase I complex#GO:0005736;nuclear protein-containing complex#GO:0140513 RNA metabolism protein#PC00031;DNA-directed RNA polymerase#PC00019 CIOIN|Ensembl=ENSCING00000006084.3|UniProtKB=F6VRU1 F6VRU1 LOC100181980 PTHR43612:SF3 TRIFUNCTIONAL ENZYME SUBUNIT ALPHA TRIFUNCTIONAL ENZYME SUBUNIT ALPHA, MITOCHONDRIAL lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;hydro-lyase activity#GO:0016836;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;lipid oxidation#GO:0034440;cellular metabolic process#GO:0044237;lipid catabolic process#GO:0016042;lipid modification#GO:0030258;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;fatty acid catabolic process#GO:0009062;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;fatty acid metabolic process#GO:0006631;small molecule catabolic process#GO:0044282;fatty acid beta-oxidation#GO:0006635;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;cellular lipid metabolic process#GO:0044255;cellular lipid catabolic process#GO:0044242;carboxylic acid metabolic process#GO:0019752;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;monocarboxylic acid catabolic process#GO:0072329 CIOIN|Ensembl=ENSCING00000002514.3|UniProtKB=F6YEL1 F6YEL1 PTHR24270:SF8 LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED LD11117P-RELATED cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 apolipoprotein#PC00052 CIOIN|Ensembl=ENSCING00000007668.3|UniProtKB=F6T7E5 F6T7E5 PTHR12474:SF0 P53 REGULATED PA26 NUCLEAR PROTEIN SESTRIN SESTRIN HOMOLOG amino acid binding#GO:0016597;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;carboxylic acid binding#GO:0031406;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;organic acid binding#GO:0043177;anion binding#GO:0043168;ion binding#GO:0043167;oxidoreductase activity#GO:0016491 negative regulation of biological process#GO:0048519;regulation of catabolic process#GO:0009894;negative regulation of intracellular signal transduction#GO:1902532;positive regulation of cellular metabolic process#GO:0031325;regulation of signaling#GO:0023051;positive regulation of cellular catabolic process#GO:0031331;response to extracellular stimulus#GO:0009991;regulation of intracellular signal transduction#GO:1902531;cellular response to nitrogen compound#GO:1901699;negative regulation of TOR signaling#GO:0032007;regulation of biological process#GO:0050789;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;cellular response to starvation#GO:0009267;positive regulation of metabolic process#GO:0009893;regulation of signal transduction#GO:0009966;positive regulation of biological process#GO:0048518;negative regulation of cell communication#GO:0010648;negative regulation of cellular process#GO:0048523;cellular response to extracellular stimulus#GO:0031668;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of TORC1 signaling#GO:1903432;cellular response to endogenous stimulus#GO:0071495;negative regulation of response to stimulus#GO:0048585;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;regulation of autophagy#GO:0010506;negative regulation of signaling#GO:0023057;cell communication#GO:0007154;regulation of macroautophagy#GO:0016241;response to organonitrogen compound#GO:0010243;response to nutrient levels#GO:0031667;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;regulation of TOR signaling#GO:0032006;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to stress#GO:0006950;positive regulation of macroautophagy#GO:0016239;response to chemical#GO:0042221;cellular response to nutrient levels#GO:0031669;cellular response to organonitrogen compound#GO:0071417;regulation of cellular process#GO:0050794;response to starvation#GO:0042594;biological regulation#GO:0065007;cellular response to external stimulus#GO:0071496;positive regulation of catabolic process#GO:0009896;negative regulation of signal transduction#GO:0009968;positive regulation of autophagy#GO:0010508;cellular response to amino acid starvation#GO:0034198;negative regulation of TORC1 signaling#GO:1904262;cellular response to stress#GO:0033554;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 peroxidase#PC00180;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000004836.3|UniProtKB=F6TZC4 F6TZC4 LOC100175771 PTHR15237:SF0 DNA REPAIR PROTEIN RAD9 CELL CYCLE CHECKPOINT CONTROL PROTEIN DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;negative regulation of biological process#GO:0048519;signal transduction#GO:0007165;DNA damage checkpoint signaling#GO:0000077;mitotic cell cycle checkpoint signaling#GO:0007093;mitotic intra-S DNA damage checkpoint signaling#GO:0031573;cell cycle process#GO:0022402;negative regulation of cell cycle process#GO:0010948;nucleobase-containing compound metabolic process#GO:0006139;mitotic cell cycle process#GO:1903047;regulation of biological process#GO:0050789;cell cycle checkpoint signaling#GO:0000075;DNA damage response#GO:0006974;mitotic cell cycle#GO:0000278;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;signal transduction in response to DNA damage#GO:0042770;response to radiation#GO:0009314;intracellular signal transduction#GO:0035556;response to abiotic stimulus#GO:0009628;negative regulation of cellular process#GO:0048523;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;negative regulation of cell cycle#GO:0045786;regulation of cell cycle phase transition#GO:1901987;negative regulation of cell cycle phase transition#GO:1901988;cellular metabolic process#GO:0044237;negative regulation of mitotic cell cycle#GO:0045930;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;regulation of cell cycle process#GO:0010564;response to stimulus#GO:0050896;DNA integrity checkpoint signaling#GO:0031570;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;DNA replication checkpoint signaling#GO:0000076;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;mitotic DNA integrity checkpoint signaling#GO:0044774;cellular response to stress#GO:0033554;mitotic DNA damage checkpoint signaling#GO:0044773;regulation of mitotic cell cycle#GO:0007346;DNA metabolic process#GO:0006259 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;condensed chromosome#GO:0000793;intracellular organelle lumen#GO:0070013;condensed nuclear chromosome#GO:0000794;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 DNA metabolism protein#PC00009;exodeoxyribonuclease#PC00098 CIOIN|Ensembl=ENSCING00000002066.3|UniProtKB=F7AAH8 F7AAH8 PTHR43206:SF1 AMINOTRANSFERASE 4-AMINOBUTYRATE AMINOTRANSFERASE, MITOCHONDRIAL transferase activity#GO:0016740;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;transaminase activity#GO:0008483;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167 oxoacid metabolic process#GO:0043436;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;amino acid catabolic process#GO:0009063;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;nitrogen compound metabolic process#GO:0006807;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;carboxylic acid metabolic process#GO:0019752;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transaminase#PC00216 Aminobutyrate degradation#P02726>4-aminobutyrate aminotransferase#P02825;Pyrimidine Metabolism#P02771>Aminotransferase#P03129;Gamma-aminobutyric acid synthesis#P04384>GABA aminotransferase#P04480 CIOIN|Ensembl=ENSCING00000017987.1|UniProtKB=H2XUU5 H2XUU5 PTHR12466:SF8 CDC73 DOMAIN PROTEIN PARAFIBROMIN basal RNA polymerase II transcription machinery binding#GO:0001099;RNA polymerase binding#GO:0070063;binding#GO:0005488;RNA polymerase core enzyme binding#GO:0043175;RNA polymerase II complex binding#GO:0000993;protein binding#GO:0005515;enzyme binding#GO:0019899;basal transcription machinery binding#GO:0001098 regulation of transcription elongation by RNA polymerase II#GO:0034243;cellular component biogenesis#GO:0044085;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;positive regulation of DNA-templated transcription, elongation#GO:0032786;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;protein-RNA complex assembly#GO:0022618;mRNA metabolic process#GO:0016071;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular component assembly#GO:0022607;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;regulation of cellular process#GO:0050794;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of transcription elongation by RNA polymerase II#GO:0032968;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;regulation of transcription by RNA polymerase II#GO:0006357;protein-containing complex assembly#GO:0065003;RNA processing#GO:0006396;biosynthetic process#GO:0009058;mRNA 3'-end processing#GO:0031124;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;regulation of DNA-templated transcription elongation#GO:0032784;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA 3'-end processing#GO:0031123;regulation of DNA-templated transcription#GO:0006355;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;protein-containing complex organization#GO:0043933;ribonucleoprotein complex biogenesis#GO:0022613;biological regulation#GO:0065007;mRNA processing#GO:0006397;protein-RNA complex organization#GO:0071826;positive regulation of RNA metabolic process#GO:0051254 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;DNA-directed RNA polymerase complex#GO:0000428;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nucleoplasm#GO:0005654;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;transcription elongation factor complex#GO:0008023;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622;RNA polymerase II, holoenzyme#GO:0016591;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;Cdc73/Paf1 complex#GO:0016593;nuclear protein-containing complex#GO:0140513 CIOIN|Ensembl=ENSCING00000021819.1|UniProtKB=H2Y3A9 H2Y3A9 PTHR24543:SF325 MULTICOPPER OXIDASE-RELATED F5_8 TYPE C DOMAIN-CONTAINING PROTEIN oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000018501.1|UniProtKB=H2XZF9 H2XZF9 ci-zf(c2h2)-87 PTHR24393:SF136 ZINC FINGER PROTEIN LD28458P-RELATED DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 CIOIN|Ensembl=ENSCING00000002659.3|UniProtKB=F6YDE8 F6YDE8 LOC104265809 PTHR21737:SF3 POLYGLUTAMINE BINDING PROTEIN 1/MARVEL MEMBRANE-ASSOCIATING DOMAIN CONTAINING 3 POLYGLUTAMINE-BINDING PROTEIN 1 ribonucleoprotein complex binding#GO:0043021;protein-containing complex binding#GO:0044877;binding#GO:0005488 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;alternative mRNA splicing, via spliceosome#GO:0000380;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear body#GO:0016604;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000001140.3|UniProtKB=F6YUP9 F6YUP9 LOC100179169 PTHR22847:SF722 WD40 REPEAT PROTEIN NOVEL PROTEIN CIOIN|Ensembl=ENSCING00000014829.2|UniProtKB=F6S8U4 F6S8U4 LOC100177969 PTHR43720:SF2 2-AMINOMUCONIC SEMIALDEHYDE DEHYDROGENASE 2-AMINOMUCONIC SEMIALDEHYDE DEHYDROGENASE oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 5-Hydroxytryptamine degredation#P04372>Aldehyde Dehydrogenase#P04402 CIOIN|Ensembl=ENSCING00000019794.1|UniProtKB=H2XLJ3 H2XLJ3 LOC100183224 PTHR11711:SF41 ADP RIBOSYLATION FACTOR-RELATED ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 1 carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167 cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 G-protein#PC00020 Integrin signalling pathway#P00034>Arf1#P00923;Huntington disease#P00029>ARF#P00786 CIOIN|Ensembl=ENSCING00000013405.2|UniProtKB=F6VR85 F6VR85 PTHR31532:SF10 BIORIENTATION OF CHROMOSOMES IN CELL DIVISION 1 FAMILY MEMBER BIORIENTATION OF CHROMOSOMES IN CELL DIVISION PROTEIN 1-LIKE 1 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;DNA-templated DNA replication#GO:0006261;replication fork processing#GO:0031297;DNA replication#GO:0006260;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 membrane-enclosed lumen#GO:0031974;histone methyltransferase complex#GO:0035097;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;methyltransferase complex#GO:0034708;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513;Set1C/COMPASS complex#GO:0048188 CIOIN|Ensembl=ENSCING00000020334.1|UniProtKB=H2XXT0 H2XXT0 LOC100181030 PTHR10438:SF463 THIOREDOXIN THIOREDOXIN oxidoreductase#PC00176 Oxidative stress response#P00046>TRX#P01122;Hypoxia response via HIF activation#P00030>Thioredoxin#P00825 CIOIN|Ensembl=ENSCING00000005559.3|UniProtKB=Q4H2T4 Q4H2T4 Ci-Smad4 PTHR13703:SF45 SMAD MOTHERS AGAINST DECAPENTAPLEGIC HOMOLOG cis-regulatory region sequence-specific DNA binding#GO:0000987;SMAD binding#GO:0046332;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;protein binding#GO:0005515;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 signal transduction#GO:0007165;regulation of nitrogen compound metabolic process#GO:0051171;response to growth factor#GO:0070848;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;cellular response to BMP stimulus#GO:0071773;cell differentiation#GO:0030154;response to endogenous stimulus#GO:0009719;anatomical structure morphogenesis#GO:0009653;regulation of biosynthetic process#GO:0009889;response to BMP#GO:0071772;regulation of macromolecule biosynthetic process#GO:0010556;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;regulation of gene expression#GO:0010468;signaling#GO:0023052;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;cellular response to endogenous stimulus#GO:0071495;regulation of DNA-templated transcription#GO:0006355;BMP signaling pathway#GO:0030509;cell communication#GO:0007154;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;cellular response to growth factor stimulus#GO:0071363;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;cell surface receptor signaling pathway#GO:0007166;anatomical structure development#GO:0048856;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218 MYO signaling pathway#P06215>MED#P06311;DPP signaling pathway#P06213>MED#P06279;DPP-SCW signaling pathway#P06212>MED#P06265;SCW signaling pathway#P06216>MED#P06323;Activin beta signaling pathway#P06210>MED#P06233;BMP/activin signaling pathway-drosophila#P06211>Co-Smad#P06254;TGF-beta signaling pathway#P00052>Co-Smads#P01276;TGF-beta signaling pathway#P00052>RSmads#P01292;ALP23B signaling pathway#P06209>MED#P06221;GBB signaling pathway#P06214>MED#P06299 CIOIN|Ensembl=ENSCING00000007703.3|UniProtKB=F6ZID9 F6ZID9 PTHR23115:SF294 TRANSLATION FACTOR ELONGATION FACTOR 1-ALPHA GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;nucleic acid binding#GO:0003676;translation regulator activity#GO:0045182;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;translation regulator activity, nucleic acid binding#GO:0090079;translation elongation factor activity#GO:0003746;translation factor activity, RNA binding#GO:0008135 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;translational elongation#GO:0006414;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 translation factor#PC00223;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000012173.2|UniProtKB=F6TV04 F6TV04 PTHR11844:SF25 METALLOPROTEASE INHIBITOR NTR DOMAIN-CONTAINING PROTEIN peptidase inhibitor activity#GO:0030414;protease binding#GO:0002020;binding#GO:0005488;molecular function regulator activity#GO:0098772;enzyme binding#GO:0019899;protein binding#GO:0005515;peptidase regulator activity#GO:0061134;enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;endopeptidase regulator activity#GO:0061135;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234 negative regulation of hydrolase activity#GO:0051346;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;regulation of catabolic process#GO:0009894;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of protein catabolic process#GO:0042177;regulation of protein catabolic process#GO:0042176;regulation of catalytic activity#GO:0050790;regulation of biological process#GO:0050789;regulation of molecular function#GO:0065009;regulation of hydrolase activity#GO:0051336;negative regulation of cellular process#GO:0048523;response to organic substance#GO:0010033;regulation of proteolysis#GO:0030162;negative regulation of endopeptidase activity#GO:0010951;negative regulation of peptidase activity#GO:0010466;negative regulation of cellular catabolic process#GO:0031330;negative regulation of metabolic process#GO:0009892;negative regulation of proteolysis#GO:0045861;regulation of cellular catabolic process#GO:0031329;negative regulation of protein metabolic process#GO:0051248;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;negative regulation of catabolic process#GO:0009895;regulation of macromolecule metabolic process#GO:0060255;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of endopeptidase activity#GO:0052548;regulation of peptidase activity#GO:0052547;negative regulation of catalytic activity#GO:0043086;regulation of metabolic process#GO:0019222;negative regulation of molecular function#GO:0044092;regulation of cellular metabolic process#GO:0031323 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;extracellular space#GO:0005615;extracellular region#GO:0005576 protease inhibitor#PC00191 CIOIN|Ensembl=ENSCING00000001238.3|UniProtKB=F7AEF7 F7AEF7 PTHR48020:SF12 PROTON MYO-INOSITOL COTRANSPORTER PROTON MYO-INOSITOL COTRANSPORTER transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 localization#GO:0051179;establishment of localization#GO:0051234;cellular process#GO:0009987;transmembrane transport#GO:0055085;transport#GO:0006810 cellular anatomical entity#GO:0110165;membrane#GO:0016020 transporter#PC00227 CIOIN|Ensembl=ENSCING00000015987.2|UniProtKB=F6WHG5 F6WHG5 LOC104265585 PTHR11371:SF33 DEOXYRIBONUCLEASE ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN hydrolase activity, acting on ester bonds#GO:0016788;DNA endonuclease activity#GO:0004520;nucleic acid binding#GO:0003676;nuclease activity#GO:0004518;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;hydrolase activity#GO:0016787;catalytic activity, acting on a nucleic acid#GO:0140640;endonuclease activity#GO:0004519;catalytic activity, acting on DNA#GO:0140097;DNA nuclease activity#GO:0004536 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;heterocycle catabolic process#GO:0046700;macromolecule metabolic process#GO:0043170;DNA catabolic process#GO:0006308;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular nitrogen compound catabolic process#GO:0044270;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;organic cyclic compound catabolic process#GO:1901361;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;nucleobase-containing compound catabolic process#GO:0034655;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259;cellular catabolic process#GO:0044248 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 endodeoxyribonuclease#PC00093 CIOIN|Ensembl=ENSCING00000007348.3|UniProtKB=F6XXY5 F6XXY5 LOC100179868 PTHR24070:SF69 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY FI18258P1 GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;ion binding#GO:0043167;anion binding#GO:0043168 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 small GTPase#PC00208;G-protein#PC00020 CIOIN|Ensembl=ENSCING00000003501.3|UniProtKB=F6TLU2 F6TLU2 LOC100187202 PTHR10342:SF274 ARYLSULFATASE ARYLSULFATASE B CIOIN|Ensembl=ENSCING00000011506.2|UniProtKB=F6WUG3 F6WUG3 LOC100176016 PTHR22798:SF0 MCT-1 PROTEIN MALIGNANT T-CELL-AMPLIFIED SEQUENCE 1 cellular component biogenesis#GO:0044085;peptide metabolic process#GO:0006518;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;translation#GO:0006412;protein-RNA complex assembly#GO:0022618;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular component assembly#GO:0022607;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cytoplasmic translation#GO:0002181;cellular component organization#GO:0016043;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;cytoplasmic translational initiation#GO:0002183;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;cellular component organization or biogenesis#GO:0071840;peptide biosynthetic process#GO:0043043;protein-containing complex organization#GO:0043933;ribonucleoprotein complex biogenesis#GO:0022613;translational initiation#GO:0006413;protein-RNA complex organization#GO:0071826 translation initiation factor#PC00224;translation factor#PC00223;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000008100.3|UniProtKB=F6UHM2 F6UHM2 PTHR10527:SF3 IMPORTIN BETA FI21453P1-RELATED signal sequence binding#GO:0005048;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277 cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;protein localization to nucleus#GO:0034504;nitrogen compound transport#GO:0071705;establishment of protein localization to organelle#GO:0072594;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;protein import into nucleus#GO:0006606;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;protein localization to organelle#GO:0033365;intracellular transport#GO:0046907;nuclear transport#GO:0051169;import into nucleus#GO:0051170 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transporter#PC00227 CIOIN|Ensembl=ENSCING00000005125.3|UniProtKB=F6VYL7 F6VYL7 PTHR23004:SF11 DOUBLECORTIN DOMAIN CONTAINING 2 PROTEIN RPI-1 CIOIN|Ensembl=ENSCING00000022111.1|UniProtKB=H2XK19 H2XK19 PTHR11984:SF53 CONNEXIN GAP JUNCTION PROTEIN wide pore channel activity#GO:0022829;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;channel activity#GO:0015267 biological regulation#GO:0065007;regulation of biological process#GO:0050789;cell communication#GO:0007154;cellular process#GO:0009987;cell-cell signaling#GO:0007267;signaling#GO:0023052 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 cell junction protein#PC00070;gap junction#PC00105 CIOIN|Ensembl=ENSCING00000012965.2|UniProtKB=F6RBM9 F6RBM9 PTHR24291:SF208 CYTOCHROME P450 FAMILY 4 SUBFAMILY NOT NAMED oxygenase#PC00177;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000001412.3|UniProtKB=F6YS67 F6YS67 PTHR47958:SF11 ATP-DEPENDENT RNA HELICASE DBP3 ATP-DEPENDENT RNA HELICASE DDX4-RELATED catalytic activity, acting on RNA#GO:0140098;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;helicase activity#GO:0004386;ATP-dependent activity#GO:0140657;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;catalytic activity, acting on a nucleic acid#GO:0140640;mRNA binding#GO:0003729 germ cell development#GO:0007281;cellular developmental process#GO:0048869;gamete generation#GO:0007276;cellular process involved in reproduction in multicellular organism#GO:0022412;multicellular organism reproduction#GO:0032504;developmental process#GO:0032502;cellular process#GO:0009987;cell development#GO:0048468;developmental process involved in reproduction#GO:0003006;cell differentiation#GO:0030154;reproduction#GO:0000003;anatomical structure development#GO:0048856;sexual reproduction#GO:0019953;reproductive process#GO:0022414;multicellular organismal process#GO:0032501;multicellular organismal reproductive process#GO:0048609 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;P granule#GO:0043186;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464;intracellular anatomical structure#GO:0005622 RNA helicase#PC00032 CIOIN|Ensembl=ENSCING00000021626.1|UniProtKB=H2XLN0 H2XLN0 LOC100186755 PTHR11679:SF85 VESICLE PROTEIN SORTING-ASSOCIATED VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 33A cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle tethering complex#GO:0099023;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;organelle#GO:0043226;lytic vacuole#GO:0000323;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;lysosome#GO:0005764;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227 membrane trafficking regulatory protein#PC00151 CIOIN|Ensembl=ENSCING00000003347.3|UniProtKB=F7AQA9 F7AQA9 PTHR11751:SF29 ALANINE AMINOTRANSFERASE ALANINE TRANSAMINASE transaminase#PC00216;transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000024300.1|UniProtKB=H2XZZ5 H2XZZ5 PTHR24092:SF5 PROBABLE PHOSPHOLIPID-TRANSPORTING ATPASE PHOSPHOLIPID-TRANSPORTING ATPASE ATPase-coupled intramembrane lipid transporter activity#GO:0140326;ATP-dependent activity#GO:0140657;transporter activity#GO:0005215;lipid transporter activity#GO:0005319 organophosphate ester transport#GO:0015748;macromolecule localization#GO:0033036;membrane organization#GO:0061024;transport#GO:0006810;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;regulation of membrane lipid distribution#GO:0097035;phospholipid transport#GO:0015914;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987;lipid transport#GO:0006869;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;biological regulation#GO:0065007;lipid translocation#GO:0034204;lipid localization#GO:0010876;import into cell#GO:0098657;phospholipid translocation#GO:0045332 trans-Golgi network#GO:0005802;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;organelle subcompartment#GO:0031984;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791;plasma membrane#GO:0005886 primary active transporter#PC00068;transporter#PC00227 CIOIN|Ensembl=ENSCING00000000710.3|UniProtKB=F6QKZ8 F6QKZ8 LOC100175225 PTHR24033:SF228 EGF-LIKE DOMAIN-CONTAINING PROTEIN EGF-LIKE DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000009589.3|UniProtKB=F6SXN2 F6SXN2 bco PTHR10543:SF132 BETA-CAROTENE DIOXYGENASE BETA,BETA-CAROTENE 15,15'-DIOXYGENASE oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;dioxygenase activity#GO:0051213 retinoid metabolic process#GO:0001523;lipid metabolic process#GO:0006629;isoprenoid catabolic process#GO:0008300;cellular metabolic process#GO:0044237;lipid catabolic process#GO:0016042;cellular process#GO:0009987;isoprenoid metabolic process#GO:0006720;primary metabolic process#GO:0044238;diterpenoid metabolic process#GO:0016101;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;cellular lipid metabolic process#GO:0044255;cellular lipid catabolic process#GO:0044242;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248;terpenoid metabolic process#GO:0006721 oxygenase#PC00177;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000011377.2|UniProtKB=F6TKD8 F6TKD8 PTHR11306:SF68 NIEMANN PICK TYPE C2 PROTEIN NPC2-RELATED NPC INTRACELLULAR CHOLESTEROL TRANSPORTER 2 lipid binding#GO:0008289;binding#GO:0005488;organic cyclic compound binding#GO:0097159;steroid binding#GO:0005496;sterol binding#GO:0032934 localization#GO:0051179;organic hydroxy compound transport#GO:0015850;organic substance transport#GO:0071702;establishment of localization#GO:0051234;macromolecule localization#GO:0033036;sterol transport#GO:0015918;transport#GO:0006810;lipid localization#GO:0010876;lipid transport#GO:0006869 CIOIN|Ensembl=ENSCING00000005628.3|UniProtKB=F7ASM2 F7ASM2 LOC100176909 PTHR24006:SF687 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 10 cysteine-type peptidase activity#GO:0008234;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;cysteine-type deubiquitinase activity#GO:0004843 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;protein modification by small protein removal#GO:0070646;protein deubiquitination#GO:0016579;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;post-translational protein modification#GO:0043687;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cysteine protease#PC00081;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000004616.3|UniProtKB=F6Q0M2 F6Q0M2 PTHR24356:SF184 SERINE/THREONINE-PROTEIN KINASE SERINE_THREONINE-PROTEIN KINASE TRICORNERED transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular process#GO:0009987;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000004539.3|UniProtKB=F6ZQU5 F6ZQU5 PTHR10155:SF32 PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT LP02169P enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207 lipid metabolic process#GO:0006629;phospholipid biosynthetic process#GO:0008654;organophosphate biosynthetic process#GO:0090407;phosphatidylinositol biosynthetic process#GO:0006661;glycerolipid biosynthetic process#GO:0045017;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;phosphatidylinositol metabolic process#GO:0046488;glycerophospholipid metabolic process#GO:0006650;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;phosphatidylinositol phosphate biosynthetic process#GO:0046854;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;glycerophospholipid biosynthetic process#GO:0046474;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;phosphatidylinositol 3-kinase complex#GO:0005942;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;membrane#GO:0016020;transferase complex, transferring phosphorus-containing groups#GO:0061695;extrinsic component of membrane#GO:0019898 kinase modulator#PC00140 CIOIN|Ensembl=ENSCING00000009131.3|UniProtKB=F6S2Y7 F6S2Y7 LOC100179114 PTHR11158:SF29 MSF1/PX19 RELATED PRELI DOMAIN-CONTAINING PROTEIN 1, MITOCHONDRIAL phospholipid transporter activity#GO:0005548;lipid transfer activity#GO:0120013;transporter activity#GO:0005215;lipid transporter activity#GO:0005319 localization#GO:0051179;organic substance transport#GO:0071702;organophosphate ester transport#GO:0015748;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;transport#GO:0006810;lipid localization#GO:0010876;phospholipid transport#GO:0015914;lipid transport#GO:0006869 envelope#GO:0031975;membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;mitochondrial envelope#GO:0005740;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;mitochondrial intermembrane space#GO:0005758;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transfer/carrier protein#PC00219 CIOIN|Ensembl=ENSCING00000020588.1|UniProtKB=A0A1W5BFR1 A0A1W5BFR1 LOC100183150 PTHR22838:SF4 WD REPEAT PROTEIN 26-RELATED WD REPEAT-CONTAINING PROTEIN 13 protein-containing complex binding#GO:0044877;chromatin binding#GO:0003682;binding#GO:0005488 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000001585.3|UniProtKB=F6VCR2 F6VCR2 LOC100183445 PTHR43477:SF4 DIHYDROANTICAPSIN 7-DEHYDROGENASE DEHYDROGENASE_REDUCTASE SDR FAMILY MEMBER 6 oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 dehydrogenase#PC00092;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000004176.3|UniProtKB=F7B658 F7B658 PTHR11618:SF4 TRANSCRIPTION INITIATION FACTOR IIB-RELATED TRANSCRIPTION FACTOR IIIB 90 KDA SUBUNIT sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690 cellular aromatic compound metabolic process#GO:0006725;DNA-templated transcription#GO:0006351;heterocycle metabolic process#GO:0046483;transcription by RNA polymerase III#GO:0006383;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;RNA biosynthetic process#GO:0032774;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;DNA-templated transcription initiation#GO:0006352;aromatic compound biosynthetic process#GO:0019438;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-DNA complex#GO:0032993;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 general transcription factor#PC00259 Transcription regulation by bZIP transcription factor#P00055>TFIIB#P01397;General transcription regulation#P00023>TFIIB#P00668 CIOIN|Ensembl=ENSCING00000019708.1|UniProtKB=H2XR44 H2XR44 PTHR11005:SF161 LYSOSOMAL ACID LIPASE-RELATED LIPASE lipase#PC00143;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000006151.3|UniProtKB=F6SEF1 F6SEF1 LOC100179943 PTHR10445:SF0 GENERAL TRANSCRIPTION FACTOR IIF SUBUNIT 2 GENERAL TRANSCRIPTION FACTOR IIF SUBUNIT 2 cellular aromatic compound metabolic process#GO:0006725;DNA-templated transcription#GO:0006351;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;RNA biosynthetic process#GO:0032774;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;transcription initiation at RNA polymerase II promoter#GO:0006367;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nucleobase-containing compound biosynthetic process#GO:0034654;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;DNA-templated transcription initiation#GO:0006352;aromatic compound biosynthetic process#GO:0019438;transcription by RNA polymerase II#GO:0006366;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;DNA-directed RNA polymerase complex#GO:0000428;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695;RNA polymerase II, holoenzyme#GO:0016591;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;transcription regulator complex#GO:0005667;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 RNA metabolism protein#PC00031;general transcription factor#PC00259 General transcription regulation#P00023>TFIIFbeta#P00667;Transcription regulation by bZIP transcription factor#P00055>TFIIFbeta#P01396 CIOIN|Ensembl=ENSCING00000018200.1|UniProtKB=H2Y1T5 H2Y1T5 err PTHR48092:SF9 KNIRPS-RELATED PROTEIN-RELATED KNIRPS-RELATED PROTEIN-RELATED sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C4 zinc finger nuclear receptor#PC00169;zinc finger transcription factor#PC00244 CIOIN|Ensembl=ENSCING00000001024.3|UniProtKB=A0A1W5BNW1 A0A1W5BNW1 LOC100183260 PTHR23137:SF36 VESICLE TRANSPORT PROTEIN-RELATED VESICLE TRANSPORT PROTEIN SFT2C CIOIN|Ensembl=ENSCING00000018459.1|UniProtKB=H2XVB8 H2XVB8 PTHR18945:SF916 NEUROTRANSMITTER GATED ION CHANNEL GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT BETA-LIKE inorganic molecular entity transmembrane transporter activity#GO:0015318;signaling receptor activity#GO:0038023;chloride channel activity#GO:0005254;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;molecular transducer activity#GO:0060089;chloride transmembrane transporter activity#GO:0015108;monoatomic anion transmembrane transporter activity#GO:0008509;inorganic anion transmembrane transporter activity#GO:0015103;transporter activity#GO:0005215;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267;transmembrane signaling receptor activity#GO:0004888 ligand-gated ion channel#PC00141;ion channel#PC00133;transporter#PC00227 CIOIN|Ensembl=ENSCING00000007880.3|UniProtKB=F6TGL0 F6TGL0 PTHR11256:SF56 BCL-2 RELATED BCL-2 BCL-2 HOMOLOGY REGION 1-3 DOMAIN-CONTAINING PROTEIN protein binding#GO:0005515;binding#GO:0005488 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0043280;intrinsic apoptotic signaling pathway in response to DNA damage#GO:0008630;signal transduction#GO:0007165;positive regulation of cysteine-type endopeptidase activity#GO:2001056;regulation of protein metabolic process#GO:0051246;apoptotic mitochondrial changes#GO:0008637;regulation of cysteine-type endopeptidase activity#GO:2000116;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;positive regulation of proteolysis#GO:0045862;regulation of biological process#GO:0050789;activation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0006919;DNA damage response#GO:0006974;positive regulation of metabolic process#GO:0009893;regulation of molecular function#GO:0065009;apoptotic process#GO:0006915;cell death#GO:0008219;regulation of hydrolase activity#GO:0051336;mitochondrion organization#GO:0007005;intracellular signal transduction#GO:0035556;positive regulation of biological process#GO:0048518;positive regulation of peptidase activity#GO:0010952;signaling#GO:0023052;regulation of proteolysis#GO:0030162;cellular response to stimulus#GO:0051716;positive regulation of catalytic activity#GO:0043085;programmed cell death#GO:0012501;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of hydrolase activity#GO:0051345;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;intrinsic apoptotic signaling pathway#GO:0097193;apoptotic signaling pathway#GO:0097190;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;response to stress#GO:0006950;extrinsic apoptotic signaling pathway#GO:0097191;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of endopeptidase activity#GO:0052548;regulation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0043281;regulation of peptidase activity#GO:0052547;release of cytochrome c from mitochondria#GO:0001836;cellular response to stress#GO:0033554;positive regulation of endopeptidase activity#GO:0010950;regulation of metabolic process#GO:0019222 bounding membrane of organelle#GO:0098588;envelope#GO:0031975;mitochondrial membrane#GO:0031966;mitochondrial outer membrane#GO:0005741;intracellular membrane-bounded organelle#GO:0043231;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867 CIOIN|Ensembl=ENSCING00000003058.3|UniProtKB=F6PPH5 F6PPH5 PTHR12356:SF3 NUCLEAR MOVEMENT PROTEIN NUDC NUCLEAR MIGRATION PROTEIN NUDC protein binding#GO:0005515;unfolded protein binding#GO:0051082;binding#GO:0005488 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein folding#GO:0006457;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;microtubule or microtubule-binding cytoskeletal protein#PC00157 CIOIN|Ensembl=ENSCING00000021363.1|UniProtKB=H2XRC8 H2XRC8 PTHR44314:SF1 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 70 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 70 cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cell projection organization#GO:0030030;microtubule-based movement#GO:0007018;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031;cilium movement#GO:0003341;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;plasma membrane bounded cell projection assembly#GO:0120031 motile cilium#GO:0031514;extracellular region#GO:0005576;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;cilium#GO:0005929;organelle#GO:0043226;vesicle#GO:0031982 structural protein#PC00211 CIOIN|Ensembl=ENSCING00000019628.1|UniProtKB=H2XVV5 H2XVV5 PTHR28621:SF1 SELENOPROTEIN S SELENOPROTEIN S cellular localization#GO:0051641;signal transduction#GO:0007165;endoplasmic reticulum unfolded protein response#GO:0030968;macromolecule localization#GO:0033036;transport#GO:0006810;protein catabolic process#GO:0030163;nitrogen compound transport#GO:0071705;organonitrogen compound catabolic process#GO:1901565;establishment of protein localization#GO:0045184;regulation of biological process#GO:0050789;organic substance transport#GO:0071702;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;response to unfolded protein#GO:0006986;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;response to organic substance#GO:0010033;macromolecule catabolic process#GO:0009057;cellular response to stimulus#GO:0051716;response to endoplasmic reticulum stress#GO:0034976;cellular response to chemical stimulus#GO:0070887;macromolecule metabolic process#GO:0043170;cellular response to organic substance#GO:0071310;organonitrogen compound metabolic process#GO:1901564;ERAD pathway#GO:0036503;cell communication#GO:0007154;response to organonitrogen compound#GO:0010243;cellular process#GO:0009987;cellular response to topologically incorrect protein#GO:0035967;primary metabolic process#GO:0044238;protein localization#GO:0008104;localization#GO:0051179;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;cellular macromolecule localization#GO:0070727;response to stress#GO:0006950;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cellular response to unfolded protein#GO:0034620;response to topologically incorrect protein#GO:0035966;protein transport#GO:0015031;biological regulation#GO:0065007;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;cellular response to stress#GO:0033554 membrane protein complex#GO:0098796;endoplasmic reticulum protein-containing complex#GO:0140534;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 CIOIN|Ensembl=ENSCING00000019660.1|UniProtKB=H2Y011 H2Y011 LOC100182807 PTHR11929:SF145 ALPHA- 1,3 -FUCOSYLTRANSFERASE ALPHA-(1,3)-FUCOSYLTRANSFERASE FUT-1 transferase activity#GO:0016740;fucosyltransferase activity#GO:0008417;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 glycosylation#GO:0070085;metabolic process#GO:0008152 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000003252.2|UniProtKB=F6Z599 F6Z599 PTHR12810:SF0 MITOCHONDRIAL 28S RIBOSOMAL PROTEIN S29 SMALL RIBOSOMAL SUBUNIT PROTEIN MS29 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;mitochondrial ribosome#GO:0005761;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;ribosomal subunit#GO:0044391;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;organellar ribosome#GO:0000313;protein-containing complex#GO:0032991;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;small ribosomal subunit#GO:0015935;ribosome#GO:0005840;mitochondrial small ribosomal subunit#GO:0005763;mitochondrial protein-containing complex#GO:0098798 ribosomal protein#PC00202;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000022921.1|UniProtKB=H2XSR9 H2XSR9 LOC100185701 PTHR31872:SF4 TRANSMEMBRANE PROTEIN 179 TRANSMEMBRANE PROTEIN 179 CIOIN|Ensembl=ENSCING00000006178.3|UniProtKB=F6U1V3 F6U1V3 PTHR31043:SF3 NEPHROCYSTIN-4 NEPHROCYSTIN-4 CIOIN|Ensembl=ENSCING00000002448.3|UniProtKB=A0A1W2WEW7 A0A1W2WEW7 LOC100186730 PTHR11205:SF18 RIBOSOMAL PROTEIN S7 SMALL RIBOSOMAL SUBUNIT PROTEIN US7 structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;structural molecule activity#GO:0005198;binding#GO:0005488;organic cyclic compound binding#GO:0097159;mRNA binding#GO:0003729;rRNA binding#GO:0019843 cellular component biogenesis#GO:0044085;peptide metabolic process#GO:0006518;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;translation#GO:0006412;protein-RNA complex assembly#GO:0022618;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;ribosome biogenesis#GO:0042254;non-membrane-bounded organelle assembly#GO:0140694;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular component assembly#GO:0022607;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;peptide biosynthetic process#GO:0043043;protein-containing complex organization#GO:0043933;organelle organization#GO:0006996;ribonucleoprotein complex biogenesis#GO:0022613;protein-RNA complex organization#GO:0071826;ribosomal small subunit biogenesis#GO:0042274 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic small ribosomal subunit#GO:0022627;cytosol#GO:0005829;small ribosomal subunit#GO:0015935;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000004597.3|UniProtKB=F6U2Q6 F6U2Q6 PTHR10030:SF37 ALPHA-L-FUCOSIDASE ALPHA-L-FUCOSIDASE-RELATED hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 monosaccharide metabolic process#GO:0005996;carbohydrate derivative metabolic process#GO:1901135;glycosyl compound catabolic process#GO:1901658;carbohydrate derivative catabolic process#GO:1901136;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;hexose metabolic process#GO:0019318;glycosyl compound metabolic process#GO:1901657;carbohydrate metabolic process#GO:0005975;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;lysosome#GO:0005764;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;lytic vacuole#GO:0000323;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosidase#PC00110;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000004392.2|UniProtKB=F7AUJ8 F7AUJ8 PTHR13030:SF8 NUDIX HYDROLASE ADP-RIBOSE PYROPHOSPHATASE, MITOCHONDRIAL metabolite interconversion enzyme#PC00262;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000004266.3|UniProtKB=F6V6R4 F6V6R4 PTHR12613:SF0 ERO1-RELATED ERO1-LIKE PROTEIN protein-disulfide reductase activity#GO:0015035;disulfide oxidoreductase activity#GO:0015036;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein folding#GO:0006457;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000006309.3|UniProtKB=F6UBS8 F6UBS8 LOC100180903 PTHR11567:SF110 ACID PHOSPHATASE-RELATED 2-PHOSPHOXYLOSE PHOSPHATASE 1 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 cellular metabolic process#GO:0044237;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;dephosphorylation#GO:0016311;metabolic process#GO:0008152 metabolite interconversion enzyme#PC00262;phosphatase#PC00181 CIOIN|Ensembl=ENSCING00000005881.3|UniProtKB=F6T4V8 F6T4V8 LOC100176038 PTHR48153:SF2 UFM1-SPECIFIC PROTEASE 2 UFM1-SPECIFIC PROTEASE 2 cysteine-type peptidase activity#GO:0008234;hydrolase activity#GO:0016787;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 CIOIN|Ensembl=ENSCING00000008423.3|UniProtKB=F6UEW3 F6UEW3 PTHR24023:SF1109 COLLAGEN ALPHA COLLAGEN ALPHA-4(IV) CHAIN-LIKE structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;external encapsulating structure organization#GO:0045229;extracellular matrix organization#GO:0030198 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;extracellular region#GO:0005576 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 CIOIN|Ensembl=ENSCING00000003110.3|UniProtKB=F6PHN1 F6PHN1 PTHR11042:SF91 EUKARYOTIC TRANSLATION INITIATION FACTOR 2-ALPHA KINASE EIF2-ALPHA KINASE -RELATED EUKARYOTIC TRANSLATION INITIATION FACTOR 2-ALPHA KINASE transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of protein metabolic process#GO:0051246;regulation of amide metabolic process#GO:0034248;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;protein modification process#GO:0036211;regulation of translational initiation#GO:0006446;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;phosphorylation#GO:0016310;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cellular process#GO:0009987;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;response to stress#GO:0006950;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;post-transcriptional regulation of gene expression#GO:0010608;biological regulation#GO:0065007;regulation of translation#GO:0006417;cellular response to stress#GO:0033554;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000013158.2|UniProtKB=F6YFG4 F6YFG4 PTHR13367:SF28 UBIQUITIN THIOESTERASE UBIQUITIN THIOESTERASE ZRANB1 cysteine-type peptidase activity#GO:0008234;ubiquitin-like protein peptidase activity#GO:0019783;K63-linked polyubiquitin modification-dependent protein binding#GO:0070530;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;protein binding#GO:0005515;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;cysteine-type deubiquitinase activity#GO:0004843;polyubiquitin modification-dependent protein binding#GO:0031593;modification-dependent protein binding#GO:0140030 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;protein modification by small protein removal#GO:0070646;proteolysis#GO:0006508;protein deubiquitination#GO:0016579;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cysteine protease#PC00081;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000010495.3|UniProtKB=F6S3U6 F6S3U6 zf(c2h2)-60 PTHR31025:SF25 SI:CH211-196P9.1-RELATED ZINC FINGER (C2H2)-60 CIOIN|Ensembl=ENSCING00000016432.2|UniProtKB=F7BCE0 F7BCE0 PTHR24256:SF570 TRYPTASE-RELATED CLIP-DOMAIN SERINE PROTEASE hydrolase activity#GO:0016787;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 serine protease#PC00203;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000013265.2|UniProtKB=F7APR6 F7APR6 LOC100182936 PTHR22663:SF17 RING FINGER PROTEIN NARYA-RELATED RING FINGER PROTEIN NARYA-RELATED transferase activity#GO:0016740;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;SUMO transferase activity#GO:0019789 homologous chromosome segregation#GO:0045143;macromolecule modification#GO:0043412;nuclear division#GO:0000280;cell cycle process#GO:0022402;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;post-translational protein modification#GO:0043687;chromosome segregation#GO:0007059;chromosome organization involved in meiotic cell cycle#GO:0070192;nitrogen compound metabolic process#GO:0006807;meiotic cell cycle process#GO:1903046;meiosis I cell cycle process#GO:0061982;reproductive process#GO:0022414;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;meiosis I#GO:0007127;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nuclear chromosome segregation#GO:0098813;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;meiotic cell cycle#GO:0051321;protein sumoylation#GO:0016925;homologous chromosome pairing at meiosis#GO:0007129;organonitrogen compound metabolic process#GO:1901564;cellular component organization#GO:0016043;cellular process#GO:0009987;meiotic chromosome segregation#GO:0045132;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;reproduction#GO:0000003;chromosome organization#GO:0051276;organelle organization#GO:0006996;meiotic nuclear division#GO:0140013;sexual reproduction#GO:0019953;cell cycle#GO:0007049;organelle fission#GO:0048285 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;condensed chromosome#GO:0000793;intracellular organelle lumen#GO:0070013;condensed nuclear chromosome#GO:0000794;synaptonemal structure#GO:0099086;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;synaptonemal complex#GO:0000795 CIOIN|Ensembl=ENSCING00000014499.2|UniProtKB=F6Q989 F6Q989 LOC100183035 PTHR45709:SF3 LARGE SUBUNIT GTPASE 1 HOMOLOG-RELATED GUANINE NUCLEOTIDE-BINDING PROTEIN-LIKE 1 GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824 CIOIN|Ensembl=ENSCING00000023813.1|UniProtKB=H2Y1Z3 H2Y1Z3 LOC100181738 PTHR36978:SF4 P-LOOP CONTAINING NUCLEOTIDE TRIPHOSPHATE HYDROLASE P-LOOP CONTAINING NUCLEOSIDE TRIPHOSPHATE HYDROLASE PROTEIN metabolite interconversion enzyme#PC00262;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000011390.2|UniProtKB=F6TJA4 F6TJA4 LOC100184661 PTHR12804:SF0 MICROSOMAL SIGNAL PEPTIDASE 23 KD SUBUNIT SPC22/23 SIGNAL PEPTIDASE COMPLEX SUBUNIT 3 cellular localization#GO:0051641;macromolecule localization#GO:0033036;peptide metabolic process#GO:0006518;gene expression#GO:0010467;biosynthetic process#GO:0009058;establishment of protein localization#GO:0045184;protein processing#GO:0016485;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;protein localization to organelle#GO:0033365;establishment of protein localization to endoplasmic reticulum#GO:0072599;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;protein localization to endoplasmic reticulum#GO:0070972;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein targeting#GO:0006605;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;establishment of protein localization to organelle#GO:0072594;protein targeting to ER#GO:0045047;protein maturation#GO:0051604;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;protein localization#GO:0008104;primary metabolic process#GO:0044238;localization#GO:0051179;cellular macromolecule localization#GO:0070727;signal peptide processing#GO:0006465 membrane protein complex#GO:0098796;peptidase complex#GO:1905368;endoplasmic reticulum protein-containing complex#GO:0140534;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 protease#PC00190;protein modifying enzyme#PC00260 Vasopressin synthesis#P04395>Signal Peptidase#P04589 CIOIN|Ensembl=ENSCING00000012894.2|UniProtKB=F6PTN3 F6PTN3 LOC100181946 PTHR24024:SF19 PULMONARY SURFACTANT-ASSOCIATED PROTEIN A FARMER, ISOFORM H extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 surfactant#PC00212;structural protein#PC00211 CIOIN|Ensembl=ENSCING00000006656.3|UniProtKB=F6U075 F6U075 LOC100179487 PTHR21707:SF42 FLAGELLUM-ASSOCIATED COILED-COIL DOMAIN-CONTAINING PROTEIN 1 FLAGELLUM-ASSOCIATED COILED-COIL DOMAIN-CONTAINING PROTEIN 1 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000011483.2|UniProtKB=F6XHG0 F6XHG0 PTHR22765:SF405 RING FINGER AND PROTEASE ASSOCIATED DOMAIN-CONTAINING E3 UBIQUITIN-PROTEIN LIGASE RNF128 PRECURSOR transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000010660.3|UniProtKB=F6Y8L3 F6Y8L3 LOC100176951 PTHR11705:SF153 PROTEASE FAMILY M14 CARBOXYPEPTIDASE A,B ZINC CARBOXYPEPTIDASE A 1-LIKE PROTEIN metalloexopeptidase activity#GO:0008235;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;metallocarboxypeptidase activity#GO:0004181;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;carboxypeptidase activity#GO:0004180 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 metalloprotease#PC00153;protease#PC00190 CIOIN|Ensembl=ENSCING00000014054.2|UniProtKB=F6QPH0 F6QPH0 PTHR10642:SF26 RIBONUCLEASE H1 RIBONUCLEASE H1 catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a nucleic acid#GO:0140640;endonuclease activity#GO:0004519;RNA nuclease activity#GO:0004540;RNA endonuclease activity#GO:0004521 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;heterocycle catabolic process#GO:0046700;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular nitrogen compound catabolic process#GO:0044270;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;organic cyclic compound catabolic process#GO:1901361;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;organic substance catabolic process#GO:1901575;nucleobase-containing compound catabolic process#GO:0034655;DNA replication#GO:0006260;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259;cellular catabolic process#GO:0044248 endoribonuclease#PC00094;RNA metabolism protein#PC00031 DNA replication#P00017>RNase H#P00538 CIOIN|Ensembl=ENSCING00000002582.3|UniProtKB=F6TRZ2 F6TRZ2 LOC100184047 PTHR11722:SF0 60S RIBOSOMAL PROTEIN L13 LARGE RIBOSOMAL SUBUNIT PROTEIN EL13 structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;structural molecule activity#GO:0005198;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic large ribosomal subunit#GO:0022625;large ribosomal subunit#GO:0015934;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;ribosomal subunit#GO:0044391 ribosomal protein#PC00202;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000022352.1|UniProtKB=H2XQX8 H2XQX8 LOC100183963 PTHR11003:SF330 POTASSIUM CHANNEL, SUBFAMILY K POTASSIUM CHANNEL DOMAIN-CONTAINING PROTEIN monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated potassium channel activity#GO:0005249;channel activity#GO:0015267;transporter activity#GO:0005215;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;regulation of membrane potential#GO:0042391;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;localization#GO:0051179;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;monoatomic cation transport#GO:0006812;potassium ion transmembrane transport#GO:0071805;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;potassium ion transport#GO:0006813 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 CIOIN|Ensembl=ENSCING00000005868.3|UniProtKB=F6T5V0 F6T5V0 PTHR11374:SF3 UDP-GLUCOSE DEHYDROGENASE/UDP-MANNAC DEHYDROGENASE UDP-GLUCOSE 6-DEHYDROGENASE dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000011660.2|UniProtKB=F6ZMJ7 F6ZMJ7 LOC100180381 PTHR10485:SF0 MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM-17 AT05822P-RELATED protein transmembrane transporter activity#GO:0008320;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 cellular localization#GO:0051641;transmembrane transport#GO:0055085;macromolecule localization#GO:0033036;transport#GO:0006810;protein transmembrane transport#GO:0071806;protein targeting#GO:0006605;nitrogen compound transport#GO:0071705;establishment of protein localization to organelle#GO:0072594;protein localization to mitochondrion#GO:0070585;cellular process#GO:0009987;protein transmembrane import into intracellular organelle#GO:0044743;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;mitochondrial transport#GO:0006839;organic substance transport#GO:0071702;protein import into mitochondrial matrix#GO:0030150;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein targeting to mitochondrion#GO:0006626;establishment of protein localization to mitochondrion#GO:0072655;protein transport#GO:0015031;protein localization to organelle#GO:0033365;mitochondrial transmembrane transport#GO:1990542 envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;TIM23 mitochondrial import inner membrane translocase complex#GO:0005744;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial envelope#GO:0005740;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227;mitochondrial protein-containing complex#GO:0098798 transporter#PC00227 CIOIN|Ensembl=ENSCING00000007347.3|UniProtKB=F6XY19 F6XY19 LOC100179971 PTHR12510:SF4 TROPONIN C-AKIN-1 PROTEIN GAMMA-GLUTAMYLAMINECYCLOTRANSFERASE cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000007169.3|UniProtKB=H2XSP5 H2XSP5 PTHR24300:SF404 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 2D6-LIKE oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;tetrapyrrole binding#GO:0046906;steroid hydroxylase activity#GO:0008395;oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497;heme binding#GO:0020037 response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;response to chemical#GO:0042221;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 oxygenase#PC00177;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000024357.1|UniProtKB=H2Y1C6 H2Y1C6 PTHR11786:SF0 N-HYDROXYARYLAMINE O-ACETYLTRANSFERASE ARYLAMINE N-ACETYLTRANSFERASE 4-RELATED acetyltransferase#PC00038 CIOIN|Ensembl=ENSCING00000008867.3|UniProtKB=F6QYI8 F6QYI8 PTHR10342:SF274 ARYLSULFATASE ARYLSULFATASE B CIOIN|Ensembl=ENSCING00000022023.1|UniProtKB=F6PSX9 F6PSX9 PTHR12274:SF3 GRANULIN PROGRANULIN cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 CIOIN|Ensembl=ENSCING00000014638.2|UniProtKB=F7BIH8 F7BIH8 LOC101243228 PTHR22588:SF3 VWFA DOMAIN-CONTAINING PROTEIN VWFA DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000001400.3|UniProtKB=F6ZBB5 F6ZBB5 LOC100183886 PTHR11985:SF15 GLYCEROL-3-PHOSPHATE DEHYDROGENASE GLYCEROL-3-PHOSPHATE DEHYDROGENASE, MITOCHONDRIAL dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000011453.2|UniProtKB=F6ZUV3 F6ZUV3 PTHR14624:SF0 DFG10 PROTEIN POLYPRENOL REDUCTASE oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;macromolecule modification#GO:0043412;alcohol biosynthetic process#GO:0046165;protein modification process#GO:0036211;organic hydroxy compound biosynthetic process#GO:1901617;lipid catabolic process#GO:0016042;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;nitrogen compound metabolic process#GO:0006807;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;cellular lipid catabolic process#GO:0044242;glycoprotein metabolic process#GO:0009100;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;organic hydroxy compound metabolic process#GO:1901615;isoprenoid catabolic process#GO:0008300;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein glycosylation#GO:0006486;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;alcohol metabolic process#GO:0006066;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;isoprenoid metabolic process#GO:0006720;primary metabolic process#GO:0044238;isoprenoid biosynthetic process#GO:0008299;carbohydrate derivative biosynthetic process#GO:1901137;small molecule catabolic process#GO:0044282;protein N-linked glycosylation#GO:0006487;small molecule biosynthetic process#GO:0044283;cellular lipid metabolic process#GO:0044255;glycosylation#GO:0070085;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000012062.2|UniProtKB=F6Z0J0 F6Z0J0 LOC100178223 PTHR20855:SF143 ADIPOR/PROGESTIN RECEPTOR-RELATED MEMBRANE PROGESTIN RECEPTOR EPSILON signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 G-protein coupled receptor#PC00021 CIOIN|Ensembl=ENSCING00000007776.3|UniProtKB=F6Q196 F6Q196 PTHR20766:SF3 LARGE NEUTRAL AMINO ACIDS TRANSPORTER SMALL SUBUNIT 4-LIKE ISOFORM X1 LARGE NEUTRAL AMINO ACIDS TRANSPORTER SMALL SUBUNIT 4-LIKE ISOFORM X1 transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;organic acid transmembrane transporter activity#GO:0005342;L-amino acid transmembrane transporter activity#GO:0015179;organic anion transmembrane transporter activity#GO:0008514;amino acid transmembrane transporter activity#GO:0015171;neutral L-amino acid transmembrane transporter activity#GO:0015175;transporter activity#GO:0005215 localization#GO:0051179;neutral amino acid transport#GO:0015804;organic substance transport#GO:0071702;establishment of localization#GO:0051234;amino acid transport#GO:0006865;organic anion transport#GO:0015711;organic acid transport#GO:0015849;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942 CIOIN|Ensembl=ENSCING00000004304.3|UniProtKB=F6SI15 F6SI15 LOC100185806 PTHR11361:SF148 DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER DNA MISMATCH REPAIR PROTEIN MSH6 nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;mismatch repair#GO:0006298;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;DNA damage response#GO:0006974;response to stress#GO:0006950;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular response to stress#GO:0033554;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA metabolism protein#PC00009 CIOIN|Ensembl=ENSCING00000008881.3|UniProtKB=F6QXI6 F6QXI6 PTHR36696:SF1 AGAP012002-PA EF-HAND DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000005163.4|UniProtKB=Q4H3F3 Q4H3F3 Ci-GCNF PTHR48092:SF18 KNIRPS-RELATED PROTEIN-RELATED NUCLEAR RECEPTOR SUBFAMILY 6 GROUP A MEMBER 1 cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;signaling receptor activity#GO:0038023;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular transducer activity#GO:0060089;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C4 zinc finger nuclear receptor#PC00169;zinc finger transcription factor#PC00244 CIOIN|Ensembl=ENSCING00000003738.3|UniProtKB=F6U6X8 F6U6X8 LOC100184817 PTHR24243:SF234 G-PROTEIN COUPLED RECEPTOR GROWTH HORMONE SECRETAGOGUE RECEPTOR TYPE 1-LIKE signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 CIOIN|Ensembl=ENSCING00000014252.2|UniProtKB=F6XB23 F6XB23 LOC100179227 PTHR24024:SF19 PULMONARY SURFACTANT-ASSOCIATED PROTEIN A FARMER, ISOFORM H extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 surfactant#PC00212;structural protein#PC00211 CIOIN|Ensembl=ENSCING00000001200.3|UniProtKB=F6TKP0 F6TKP0 LOC100183818 PTHR11475:SF121 OXIDASE/PEROXIDASE THYROID PEROXIDASE-LIKE oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;antioxidant activity#GO:0016209;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 peroxidase#PC00180;oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000020446.1|UniProtKB=H2XW54 H2XW54 PTHR12202:SF0 ESF1 HOMOLOG ESF1 HOMOLOG nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 CIOIN|Ensembl=ENSCING00000008740.3|UniProtKB=F6TME4 F6TME4 PTHR45901:SF7 PROTEIN CBG12474 OXYGEN-REGULATED PROTEIN 1 CIOIN|Ensembl=ENSCING00000007273.3|UniProtKB=F6SW71 F6SW71 PTHR11920:SF494 GUANYLYL CYCLASE ATRIAL NATRIURETIC PEPTIDE RECEPTOR 2 adenylate cyclase activity#GO:0004016;signaling receptor activity#GO:0038023;cyclase activity#GO:0009975;phosphorus-oxygen lyase activity#GO:0016849;catalytic activity#GO:0003824;lyase activity#GO:0016829;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653 cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;signal transduction#GO:0007165;cyclic nucleotide metabolic process#GO:0009187;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;signaling#GO:0023052;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cell communication#GO:0007154;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;response to stimulus#GO:0050896;ribonucleotide biosynthetic process#GO:0009260;enzyme-linked receptor protein signaling pathway#GO:0007167;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;cGMP biosynthetic process#GO:0006182;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 guanylate cyclase#PC00114 Gonadotropin-releasing hormone receptor pathway#P06664>Npr2#P06796;Endothelin signaling pathway#P00019>Guanylate cyclase#P00581 CIOIN|Ensembl=ENSCING00000020772.1|UniProtKB=H2XPF2 H2XPF2 PTHR28574:SF1 RIKEN CDNA 6820408C15 RIKEN CDNA 6820408C15 GENE CIOIN|Ensembl=ENSCING00000012842.2|UniProtKB=F6W304 F6W304 PTHR33442:SF1 TRANS-3-HYDROXY-L-PROLINE DEHYDRATASE TRANS-3-HYDROXY-L-PROLINE DEHYDRATASE dehydratase#PC00091;lyase#PC00144 CIOIN|Ensembl=ENSCING00000003519.3|UniProtKB=F7BHG2 F7BHG2 LOC100183795 PTHR10333:SF103 INHIBITOR OF GROWTH PROTEIN INHIBITOR OF GROWTH PROTEIN 3 chromatin/chromatin-binding, or -regulatory protein#PC00077 CIOIN|Ensembl=ENSCING00000011410.2|UniProtKB=F7AXI1 F7AXI1 PTHR12832:SF11 TESTIS-SPECIFIC PROTEIN PBS13 T-COMPLEX 11 LD23868P regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cytoskeletal protein#PC00085;microtubule or microtubule-binding cytoskeletal protein#PC00157 CIOIN|Ensembl=ENSCING00000004219.3|UniProtKB=F6YGS0 F6YGS0 PTHR10264:SF127 BAND 7 PROTEIN-RELATED PODOCIN cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cytoskeletal protein#PC00085 CIOIN|Ensembl=ENSCING00000009512.3|UniProtKB=F6XJ18 F6XJ18 PTHR12419:SF10 OTU DOMAIN CONTAINING PROTEIN DEUBIQUITINASE OTUD6B cysteine-type peptidase activity#GO:0008234;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;cysteine-type deubiquitinase activity#GO:0004843 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;protein modification by small protein removal#GO:0070646;protein deubiquitination#GO:0016579;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cysteine protease#PC00081;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000009392.3|UniProtKB=F6UA87 F6UA87 PTHR48109:SF4 DIHYDROOROTATE DEHYDROGENASE (QUINONE), MITOCHONDRIAL-RELATED DIHYDROOROTATE DEHYDROGENASE (QUINONE), MITOCHONDRIAL oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;pyrimidine nucleotide metabolic process#GO:0006220;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;pyrimidine-containing compound metabolic process#GO:0072527;biosynthetic process#GO:0009058;nucleobase metabolic process#GO:0009112;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;pyrimidine nucleobase metabolic process#GO:0006206;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 dehydrogenase#PC00092;oxidoreductase#PC00176 De novo pyrimidine ribonucleotides biosythesis#P02740>Dihydrooratate oxidase#P02927 CIOIN|Ensembl=ENSCING00000024037.1|UniProtKB=H2Y026 H2Y026 LOC100176801 PTHR12773:SF0 UPF0315 PROTEIN-RELATED MULTIFUNCTIONAL METHYLTRANSFERASE SUBUNIT TRM112-LIKE PROTEIN cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;cellular component biogenesis#GO:0044085;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;RNA modification#GO:0009451;rRNA modification#GO:0000154;tRNA processing#GO:0008033;RNA processing#GO:0006396;protein modification process#GO:0036211;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;tRNA modification#GO:0006400;ncRNA metabolic process#GO:0034660;tRNA methylation#GO:0030488;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;ribosome biogenesis#GO:0042254;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;rRNA methylation#GO:0031167;nucleic acid metabolic process#GO:0090304;macromolecule methylation#GO:0043414;methylation#GO:0032259;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;rRNA base methylation#GO:0070475;RNA methylation#GO:0001510 CIOIN|Ensembl=ENSCING00000021205.1|UniProtKB=H2Y2P7 H2Y2P7 PTHR11214:SF283 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE N-ACETYLLACTOSAMINIDE BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE 4-LIKE transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;protein O-linked glycosylation#GO:0006493;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 bounding membrane of organelle#GO:0098588;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;Golgi membrane#GO:0000139;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111 CIOIN|Ensembl=ENSCING00000019359.1|UniProtKB=H2XVJ2 H2XVJ2 PTHR47227:SF5 DNA-DIRECTED RNA POLYMERASE SUBUNIT K DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC2 catalytic activity, acting on RNA#GO:0140098;5'-3' RNA polymerase activity#GO:0034062;transferase activity#GO:0016740;DNA-directed 5'-3' RNA polymerase activity#GO:0003899;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;RNA polymerase activity#GO:0097747;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring phosphorus-containing groups#GO:0016772;RNA polymerase III activity#GO:0001056;RNA polymerase II activity#GO:0001055;RNA polymerase I activity#GO:0001054 cellular aromatic compound metabolic process#GO:0006725;DNA-templated transcription#GO:0006351;tRNA metabolic process#GO:0006399;RNA metabolic process#GO:0016070;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;ncRNA metabolic process#GO:0034660;transcription by RNA polymerase I#GO:0006360;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;heterocycle metabolic process#GO:0046483;transcription by RNA polymerase III#GO:0006383;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;ncRNA transcription#GO:0098781;aromatic compound biosynthetic process#GO:0019438;transcription by RNA polymerase II#GO:0006366 RNA metabolism protein#PC00031;DNA-directed RNA polymerase#PC00019 Transcription regulation by bZIP transcription factor#P00055>RNA Polymerase II#P01388;General transcription regulation#P00023>RNA Polymerase II#P00660 CIOIN|Ensembl=ENSCING00000012994.2|UniProtKB=F6V7G7 F6V7G7 PTHR10388:SF4 EUKARYOTIC TRANSLATION INITIATION FACTOR SUI1 EUKARYOTIC TRANSLATION INITIATION FACTOR EIF1 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 translation initiation factor#PC00224;translation factor#PC00223;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000002655.3|UniProtKB=F6YDP2 F6YDP2 PTHR23007:SF11 CBL E3 UBIQUITIN-PROTEIN LIGASE CBL transferase activity#GO:0016740;acyltransferase activity#GO:0016746;SH3 domain binding#GO:0017124;ubiquitin-protein transferase activity#GO:0004842;binding#GO:0005488;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;protein binding#GO:0005515;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 membrane raft#GO:0045121;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;membrane microdomain#GO:0098857;plasma membrane#GO:0005886 ligase#PC00142;metabolite interconversion enzyme#PC00262 EGF receptor signaling pathway#P00018>c-Cbl#P00544 CIOIN|Ensembl=ENSCING00000019531.1|UniProtKB=H2XSK6 H2XSK6 LOC100187478 PTHR44298:SF1 DNAJ HOMOLOG SUBFAMILY B MEMBER 11 DNAJ HOMOLOG SUBFAMILY B MEMBER 11 chaperone#PC00072 CIOIN|Ensembl=ENSCING00000007381.3|UniProtKB=H2XPV7 H2XPV7 LOC100181010 PTHR12778:SF9 SOLUTE CARRIER FAMILY 33 ACETYL-COA TRANSPORTER -RELATED ACETYL-COENZYME A TRANSPORTER 1 secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000012203.2|UniProtKB=F7BPT5 F7BPT5 PTHR10252:SF79 HISTONE-LIKE TRANSCRIPTION FACTOR CCAAT-RELATED DNA POLYMERASE EPSILON SUBUNIT 4 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;DNA-templated DNA replication#GO:0006261;DNA replication#GO:0006260;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;catalytic complex#GO:1902494;transferase complex#GO:1990234;epsilon DNA polymerase complex#GO:0008622;ATPase complex#GO:1904949;intracellular organelle lumen#GO:0070013;intracellular protein-containing complex#GO:0140535;SWI/SNF superfamily-type complex#GO:0070603;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695;DNA polymerase complex#GO:0042575;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 DNA-binding transcription factor#PC00218 CIOIN|Ensembl=ENSCING00000006465.3|UniProtKB=F6V4D1 F6V4D1 LOC100183091 PTHR22923:SF113 CEREBELLIN-RELATED COMPLEMENT C1Q-LIKE PROTEIN 4 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000004856.3|UniProtKB=F6TCF8 F6TCF8 LOC100176507 PTHR45806:SF1 SYNAPTOBREVIN HOMOLOG YKT6 SYNAPTOBREVIN HOMOLOG YKT6 molecular adaptor activity#GO:0060090;SNAP receptor activity#GO:0005484;protein-macromolecule adaptor activity#GO:0030674 localization#GO:0051179;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;establishment of localization#GO:0051234;transport#GO:0006810;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000021324.1|UniProtKB=H2XLY1 H2XLY1 PTHR15660:SF1 BRISC AND BRCA1-A COMPLEX MEMBER 1 BRISC AND BRCA1-A COMPLEX MEMBER 1 CIOIN|Ensembl=ENSCING00000003638.3|UniProtKB=F6YVN9 F6YVN9 PTHR24006:SF944 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE cysteine-type peptidase activity#GO:0008234;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;cysteine-type deubiquitinase activity#GO:0004843 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;protein modification by small protein removal#GO:0070646;protein deubiquitination#GO:0016579;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;post-translational protein modification#GO:0043687;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cysteine protease#PC00081;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000021078.1|UniProtKB=H2Y0T7 H2Y0T7 fut8 PTHR13132:SF29 ALPHA- 1,6 -FUCOSYLTRANSFERASE ALPHA-(1,6)-FUCOSYLTRANSFERASE transferase activity#GO:0016740;fucosyltransferase activity#GO:0008417;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein glycosylation#GO:0006486;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein N-linked glycosylation#GO:0006487;protein metabolic process#GO:0019538;glycosylation#GO:0070085;glycoprotein metabolic process#GO:0009100;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 glycosyltransferase#PC00111 Notch signaling pathway#P00045>Neurotic#P01115 CIOIN|Ensembl=ENSCING00000001443.3|UniProtKB=F6W7C2 F6W7C2 PTHR16083:SF85 LEUCINE RICH REPEAT CONTAINING PROTEIN FI16115P1 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000012674.2|UniProtKB=F6QE95 F6QE95 PTHR36978:SF4 P-LOOP CONTAINING NUCLEOTIDE TRIPHOSPHATE HYDROLASE P-LOOP CONTAINING NUCLEOSIDE TRIPHOSPHATE HYDROLASE PROTEIN metabolite interconversion enzyme#PC00262;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000003838.3|UniProtKB=F7A5R5 F7A5R5 LOC778718 PTHR48112:SF22 HIGH MOBILITY GROUP PROTEIN DSP1 MITOCHONDRIAL TRANSCRIPTION FACTOR A, ISOFORM B HMG box transcription factor#PC00024 CIOIN|Ensembl=ENSCING00000021950.1|UniProtKB=H2XU87 H2XU87 LOC100178918 PTHR10036:SF3 CD59 GLYCOPROTEIN PROTEIN SLEEPLESS-RELATED CIOIN|Ensembl=ENSCING00000011834.2|UniProtKB=F6ZLG3 F6ZLG3 PTHR32055:SF1 INTEGRIN BETA-1-BINDING PROTEIN 1 INTEGRIN BETA-1-BINDING PROTEIN 1 cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;integrin binding#GO:0005178;binding#GO:0005488;signaling receptor binding#GO:0005102 regulation of biological process#GO:0050789;regulation of cell-matrix adhesion#GO:0001952;negative regulation of biological process#GO:0048519;regulation of cellular component biogenesis#GO:0044087;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of cellular component organization#GO:0051128;regulation of cell junction assembly#GO:1901888;negative regulation of cellular component organization#GO:0051129;regulation of cell adhesion#GO:0030155;negative regulation of cellular process#GO:0048523;regulation of cell-substrate adhesion#GO:0010810;negative regulation of cell adhesion#GO:0007162 intracellular non-membrane-bounded organelle#GO:0043232;cell leading edge#GO:0031252;non-membrane-bounded organelle#GO:0043228;lamellipodium#GO:0030027;ruffle#GO:0001726;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000013190.2|UniProtKB=F6QJB5 F6QJB5 PTHR46246:SF1 GUANOSINE-3',5'-BIS(DIPHOSPHATE) 3'-PYROPHOSPHOHYDROLASE MESH1 GUANOSINE-3',5'-BIS(DIPHOSPHATE) 3'-PYROPHOSPHOHYDROLASE MESH1 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000017395.2|UniProtKB=F6ZM16 F6ZM16 LOC100184890 PTHR21377:SF1 PROTEIN FAM210B, MITOCHONDRIAL PROTEIN FAM210A cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000024260.1|UniProtKB=H2XXY8 H2XXY8 LOC100184548 PTHR12612:SF9 NUCLEAR TRANSPORT FACTOR 2 NTF2-RELATED EXPORT PROTEIN 2-RELATED poly(A)+ mRNA export from nucleus#GO:0016973;mRNA export from nucleus#GO:0006406;cellular localization#GO:0051641;macromolecule biosynthetic process#GO:0009059;macromolecule localization#GO:0033036;establishment of RNA localization#GO:0051236;macromolecule metabolic process#GO:0043170;transport#GO:0006810;nucleic acid transport#GO:0050657;nitrogen compound transport#GO:0071705;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;mRNA transport#GO:0051028;RNA localization#GO:0006403;localization#GO:0051179;organic substance transport#GO:0071702;nuclear export#GO:0051168;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;RNA transport#GO:0050658;nucleobase-containing compound transport#GO:0015931;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;nuclear transport#GO:0051169;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 envelope#GO:0031975;nuclear pore#GO:0005643;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear envelope#GO:0005635;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;organelle envelope#GO:0031967;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000011408.2|UniProtKB=F7AXQ6 F7AXQ6 PTHR43385:SF1 RIBOFLAVIN TRANSPORTER RIBJ RIBOFLAVIN TRANSPORTER RIBJ transporter#PC00227 CIOIN|Ensembl=ENSCING00000007871.2|UniProtKB=F6THA9 F6THA9 LOC100180883 PTHR21255:SF7 T-COMPLEX-ASSOCIATED-TESTIS-EXPRESSED 1/ DYNEIN LIGHT CHAIN DYNEIN LIGHT CHAIN TCTEX-TYPE PROTEIN 2B protein binding#GO:0005515;binding#GO:0005488 microtubule-based movement#GO:0007018;cellular process#GO:0009987;microtubule-based process#GO:0007017 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;microtubule cytoskeleton#GO:0015630;dynein complex#GO:0030286;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic dynein complex#GO:0005868;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;microtubule or microtubule-binding cytoskeletal protein#PC00157 CIOIN|Ensembl=ENSCING00000020399.1|UniProtKB=H2Y2H9 H2Y2H9 PTHR43223:SF2 ALKYL/ARYL-SULFATASE METALLO-BETA-LACTAMASE DOMAIN-CONTAINING PROTEIN metabolite interconversion enzyme#PC00262;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000004122.3|UniProtKB=F6XUA1 F6XUA1 LOC100186426 PTHR13503:SF3 NEGATIVE ELONGATION FACTOR COMPLEX MEMBER B NEGATIVE ELONGATION FACTOR B CIOIN|Ensembl=ENSCING00000023460.1|UniProtKB=H2Y2B9 H2Y2B9 PTHR35378:SF1 UNNAMED PRODUCT C2H2-TYPE DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000008544.3|UniProtKB=F6YCY6 F6YCY6 PTHR22809:SF11 METHYLTRANSFERASE-RELATED TRNA N(3)-METHYLCYTIDINE METHYLTRANSFERASE METTL2 methyltransferase#PC00155 CIOIN|Ensembl=ENSCING00000002268.3|UniProtKB=F6W2H8 F6W2H8 LOC100182863 PTHR22811:SF50 TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN 2 endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;Golgi organization#GO:0007030;macromolecule localization#GO:0033036;transport#GO:0006810;endomembrane system organization#GO:0010256;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;organelle organization#GO:0006996;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 COPII-coated ER to Golgi transport vesicle#GO:0030134;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;cellular anatomical entity#GO:0110165;organelle#GO:0043226;coated vesicle#GO:0030135;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;endoplasmic reticulum#GO:0005783;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793 vesicle coat protein#PC00235 CIOIN|Ensembl=ENSCING00000018441.1|UniProtKB=H2XTZ0 H2XTZ0 PTHR11214:SF283 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE N-ACETYLLACTOSAMINIDE BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE 4-LIKE transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;protein O-linked glycosylation#GO:0006493;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 bounding membrane of organelle#GO:0098588;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;Golgi membrane#GO:0000139;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111 CIOIN|Ensembl=ENSCING00000013284.2|UniProtKB=F7BLL2 F7BLL2 PTHR24248:SF195 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR D(1) DOPAMINE RECEPTOR-LIKE signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of MAPK cascade#GO:0043408;signal transduction#GO:0007165;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;cell communication#GO:0007154;cellular process#GO:0009987;regulation of intracellular signal transduction#GO:1902531;positive regulation of MAPK cascade#GO:0043410;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 CIOIN|Ensembl=ENSCING00000009369.3|UniProtKB=F6WY28 F6WY28 PTHR11785:SF315 AMINO ACID TRANSPORTER LARGE NEUTRAL AMINO ACIDS TRANSPORTER SMALL SUBUNIT 1 transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;organic acid transmembrane transporter activity#GO:0005342;L-amino acid transmembrane transporter activity#GO:0015179;organic anion transmembrane transporter activity#GO:0008514;amino acid transmembrane transporter activity#GO:0015171;neutral L-amino acid transmembrane transporter activity#GO:0015175;transporter activity#GO:0005215 localization#GO:0051179;neutral amino acid transport#GO:0015804;organic substance transport#GO:0071702;amino acid transmembrane transport#GO:0003333;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;amino acid transport#GO:0006865;organic anion transport#GO:0015711;organic acid transport#GO:0015849;transport#GO:0006810;nitrogen compound transport#GO:0071705;organic acid transmembrane transport#GO:1903825;carboxylic acid transport#GO:0046942;cellular process#GO:0009987;carboxylic acid transmembrane transport#GO:1905039 transporter#PC00227 CIOIN|Ensembl=ENSCING00000005071.3|UniProtKB=F6ZM33 F6ZM33 PTHR10044:SF139 INHIBITOR OF APOPTOSIS DEATH-ASSOCIATED INHIBITOR OF APOPTOSIS 2 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protease inhibitor#PC00191 CIOIN|Ensembl=ENSCING00000008706.3|UniProtKB=F6WCU4 F6WCU4 PTHR15696:SF7 SMG-7 SUPPRESSOR WITH MORPHOLOGICAL EFFECT ON GENITALIA PROTEIN 7 NONSENSE-MEDIATED MRNA DECAY FACTOR telomeric DNA binding#GO:0042162;sequence-specific DNA binding#GO:0043565;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;heterocycle catabolic process#GO:0046700;RNA metabolic process#GO:0016070;nucleobase-containing compound metabolic process#GO:0006139;cellular nitrogen compound catabolic process#GO:0044270;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;mRNA catabolic process#GO:0006402;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance catabolic process#GO:1901575;negative regulation of cellular process#GO:0048523;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;negative regulation of biosynthetic process#GO:0009890;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;nuclear-transcribed mRNA catabolic process#GO:0000956;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;nuclear-transcribed mRNA catabolic process, nonsense-mediated decay#GO:0000184;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;nucleobase-containing compound catabolic process#GO:0034655;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000005633.3|UniProtKB=F7A9J1 F7A9J1 PTHR11347:SF179 CYCLIC NUCLEOTIDE PHOSPHODIESTERASE 3',5'-CYCLIC PHOSPHODIESTERASE PDE-3-RELATED hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;cyclic-nucleotide phosphodiesterase activity#GO:0004112;phosphoric diester hydrolase activity#GO:0008081;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;cellular process#GO:0009987;cAMP-mediated signaling#GO:0019933;signaling#GO:0023052;cyclic-nucleotide-mediated signaling#GO:0019935 phosphodiesterase#PC00185 CIOIN|Ensembl=ENSCING00000005197.3|UniProtKB=F7B704 F7B704 LOC100180675 PTHR22904:SF523 TPR REPEAT CONTAINING PROTEIN STRESS-INDUCED-PHOSPHOPROTEIN 1 heat shock protein binding#GO:0031072;protein binding#GO:0005515;binding#GO:0005488;Hsp90 protein binding#GO:0051879 CIOIN|Ensembl=ENSCING00000006989.3|UniProtKB=F6SBY9 F6SBY9 ciaxp66.0 PTHR21694:SF18 COILED-COIL DOMAIN-CONTAINING PROTEIN 63 COILED-COIL DOMAIN-CONTAINING PROTEIN 63 CIOIN|Ensembl=ENSCING00000018468.1|UniProtKB=H2Y3H5 H2Y3H5 PTHR24070:SF263 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY RAS-RELATED PROTEIN RAP1 GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;ion binding#GO:0043167;anion binding#GO:0043168 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 small GTPase#PC00208;G-protein#PC00020 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Rap1#P00703;Integrin signalling pathway#P00034>Rap1#P00906;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Rap1#P00734 CIOIN|Ensembl=ENSCING00000000512.3|UniProtKB=F6VPT6 F6VPT6 LOC100183246 PTHR12395:SF9 DOM-3 RELATED DECAPPING AND EXORIBONUCLEASE PROTEIN catalytic activity, acting on RNA#GO:0140098;pyrophosphatase activity#GO:0016462;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;heterocycle catabolic process#GO:0046700;RNA metabolic process#GO:0016070;nucleobase-containing compound metabolic process#GO:0006139;cellular nitrogen compound catabolic process#GO:0044270;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;RNA decapping#GO:0110154;organic cyclic compound metabolic process#GO:1901360;mRNA catabolic process#GO:0006402;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;organic substance catabolic process#GO:1901575;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;negative regulation of biosynthetic process#GO:0009890;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;nuclear-transcribed mRNA catabolic process#GO:0000956;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;nucleobase-containing compound catabolic process#GO:0034655;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000008847.3|UniProtKB=F6R4B5 F6R4B5 LOC100181883 PTHR11134:SF1 ADAPTOR COMPLEX SUBUNIT BETA FAMILY MEMBER AP-3 COMPLEX SUBUNIT BETA localization#GO:0051179;vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234;cellular process#GO:0009987;transport#GO:0006810 membrane traffic protein#PC00150 CIOIN|Ensembl=ENSCING00000005353.2|UniProtKB=F6S741 F6S741 PTHR24256:SF570 TRYPTASE-RELATED CLIP-DOMAIN SERINE PROTEASE hydrolase activity#GO:0016787;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 serine protease#PC00203;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000020865.1|UniProtKB=H2XJU2 H2XJU2 MED18 PTHR13321:SF2 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION, SUBUNIT 18 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 18 molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;protein-macromolecule adaptor activity#GO:0030674 cellular aromatic compound metabolic process#GO:0006725;DNA-templated transcription#GO:0006351;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;regulation of DNA-templated transcription#GO:0006355;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;transcription by RNA polymerase II#GO:0006366;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;core mediator complex#GO:0070847;RNA polymerase II transcription regulator complex#GO:0090575;mediator complex#GO:0016592;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031;general transcription factor#PC00259 CIOIN|Ensembl=ENSCING00000022954.1|UniProtKB=H2XKR9 H2XKR9 LOC100184738 PTHR45710:SF26 C-TYPE LECTIN DOMAIN-CONTAINING PROTEIN 180 RH26557P defense/immunity protein#PC00090 CIOIN|Ensembl=ENSCING00000007518.3|UniProtKB=F6UJ88 F6UJ88 LOC100183715 PTHR13193:SF0 CGI-140 PAT COMPLEX SUBUNIT ASTERIX protein insertion into ER membrane#GO:0045048;localization within membrane#GO:0051668;cellular localization#GO:0051641;endoplasmic reticulum organization#GO:0007029;macromolecule localization#GO:0033036;membrane organization#GO:0061024;protein localization to membrane#GO:0072657;endomembrane system organization#GO:0010256;cellular component organization#GO:0016043;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of protein localization to membrane#GO:0090150;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;organelle organization#GO:0006996;protein localization to organelle#GO:0033365;protein insertion into membrane#GO:0051205 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000024390.1|UniProtKB=F6ZP94 F6ZP94 LOC100182260 PTHR15162:SF7 ASPARTOACYLASE SUCCINYLGLUTAMATE DESUCCINYLASE CIOIN|Ensembl=ENSCING00000003598.3|UniProtKB=F6UXR3 F6UXR3 PTHR10943:SF1 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 2 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 peptidase complex#GO:1905368;proteasome accessory complex#GO:0022624;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;proteasome regulatory particle#GO:0005838;catalytic complex#GO:1902494;proteasome complex#GO:0000502;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;endopeptidase complex#GO:1905369;membrane-bounded organelle#GO:0043227 protease#PC00190;protein modifying enzyme#PC00260 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489 CIOIN|Ensembl=ENSCING00000005285.3|UniProtKB=Q4H2Y1 Q4H2Y1 Ci-Pitx PTHR45882:SF3 PITUITARY HOMEOBOX HOMOLOG PTX1 PITUITARY HOMEOBOX HOMOLOG PTX1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;anatomical structure morphogenesis#GO:0009653;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 CIOIN|Ensembl=ENSCING00000017913.1|UniProtKB=H2XZG7 H2XZG7 LOC100187330 PTHR45942:SF1 PROTEIN PHOSPATASE 3 REGULATORY SUBUNIT B ALPHA ISOFORM TYPE 1 PROTEIN PHOSPHATASE 3 REGULATORY SUBUNIT B, ALPHA phosphatase binding#GO:0019902;phosphatase regulator activity#GO:0019208;binding#GO:0005488;molecular function regulator activity#GO:0098772;protein phosphatase regulator activity#GO:0019888;protein binding#GO:0005515;enzyme binding#GO:0019899;enzyme regulator activity#GO:0030234 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;calcium-mediated signaling#GO:0019722;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;calcineurin-mediated signaling#GO:0097720;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein dephosphorylation#GO:0006470;cellular metabolic process#GO:0044237;cell communication#GO:0007154;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;dephosphorylation#GO:0016311;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;intracellular signal transduction#GO:0035556;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 protein serine/threonine phosphatase complex#GO:0008287;intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;catalytic complex#GO:1902494 Wnt signaling pathway#P00057>Calcineurin#P01446 CIOIN|Ensembl=ENSCING00000011882.2|UniProtKB=F6ZJ92 F6ZJ92 LOC100186083 PTHR46263:SF1 ARMADILLO REPEAT-CONTAINING PROTEIN 7 ARMADILLO REPEAT-CONTAINING PROTEIN 7 CIOIN|Ensembl=ENSCING00000014051.2|UniProtKB=F6QPS8 F6QPS8 PTHR21425:SF2 NICE-3 PROTEIN C1ORF43 CIOIN|Ensembl=ENSCING00000013351.2|UniProtKB=F6YX22 F6YX22 PTHR12629:SF0 DIPHOSPHOINOSITOL POLYPHOSPHATE PHOSPHOHYDROLASE DIPHOSPHOINOSITOL-POLYPHOSPHATE DIPHOSPHATASE cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;phosphatase#PC00181;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000003211.3|UniProtKB=F6S2W5 F6S2W5 LOC100184240 PTHR24068:SF141 UBIQUITIN-CONJUGATING ENZYME E2 AT16033P-RELATED ubiquitin-like protein conjugating enzyme activity#GO:0061650;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin conjugating enzyme activity#GO:0061631;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;protein ubiquitination#GO:0016567;cellular response to stimulus#GO:0051716;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;postreplication repair#GO:0006301;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;post-translational protein modification#GO:0043687;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;response to stress#GO:0006950;nitrogen compound metabolic process#GO:0006807;protein polyubiquitination#GO:0000209;cellular response to stress#GO:0033554;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;protein K63-linked ubiquitination#GO:0070534;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 Toll receptor signaling pathway#P00054>Ubc13#P01381;Ubiquitin proteasome pathway#P00060>E2#P01491 CIOIN|Ensembl=ENSCING00000011457.2|UniProtKB=F7BBC3 F7BBC3 LOC101242368 PTHR33444:SF2 SI:DKEY-19B23.12-RELATED MARVEL DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000006862.3|UniProtKB=F6YUT1 F6YUT1 LOC100183092 PTHR11533:SF174 PROTEASE M1 ZINC METALLOPROTEASE PUROMYCIN-SENSITIVE AMINOPEPTIDASE-RELATED metalloexopeptidase activity#GO:0008235;metallopeptidase activity#GO:0008237;small molecule binding#GO:0036094;zinc ion binding#GO:0008270;binding#GO:0005488;catalytic activity#GO:0003824;transition metal ion binding#GO:0046914;amide binding#GO:0033218;metal ion binding#GO:0046872;peptidase activity#GO:0008233;metalloaminopeptidase activity#GO:0070006;cation binding#GO:0043169;peptide binding#GO:0042277;hydrolase activity#GO:0016787;aminopeptidase activity#GO:0004177;exopeptidase activity#GO:0008238;ion binding#GO:0043167;catalytic activity, acting on a protein#GO:0140096 nitrogen compound metabolic process#GO:0006807;peptide metabolic process#GO:0006518;organonitrogen compound metabolic process#GO:1901564;catabolic process#GO:0009056;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;peptide catabolic process#GO:0043171;organic substance catabolic process#GO:1901575;cellular process#GO:0009987;amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;membrane#GO:0016020;extracellular region#GO:0005576;intracellular anatomical structure#GO:0005622 metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000007908.3|UniProtKB=F6ST69 F6ST69 LOC100179788 PTHR11705:SF91 PROTEASE FAMILY M14 CARBOXYPEPTIDASE A,B FI01817P-RELATED metalloexopeptidase activity#GO:0008235;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;metallocarboxypeptidase activity#GO:0004181;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;carboxypeptidase activity#GO:0004180 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 metalloprotease#PC00153;protease#PC00190 CIOIN|Ensembl=ENSCING00000018040.1|UniProtKB=H2XUV6 H2XUV6 PTHR12961:SF0 CONSERVED OLIGOMERIC GOLGI COMPLEX COMPONENT 2 CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 2 localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;Golgi organization#GO:0007030;establishment of localization#GO:0051234;intra-Golgi vesicle-mediated transport#GO:0006891;organelle organization#GO:0006996;transport#GO:0006810;endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;vesicle tethering complex#GO:0099023;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;Golgi transport complex#GO:0017119;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000021543.1|UniProtKB=H2XWS2 H2XWS2 LOC100182190 PTHR13538:SF4 N-ACETYLTRANSFERASE 6 N-ALPHA-ACETYLTRANSFERASE 80 carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;acyltransferase activity#GO:0016746;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;amide binding#GO:0033218;N-acyltransferase activity#GO:0016410;N-acetyltransferase activity#GO:0008080;transferase activity#GO:0016740;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acetyltransferase activity#GO:0016407;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167 macromolecule modification#GO:0043412;nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein acylation#GO:0043543;protein metabolic process#GO:0019538;protein acetylation#GO:0006473;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;primary metabolic process#GO:0044238 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000009017.3|UniProtKB=F6RC25 F6RC25 LOC100186602 PTHR11599:SF15 PROTEASOME SUBUNIT ALPHA/BETA PROTEASOME SUBUNIT ALPHA TYPE-7-1-RELATED macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 protease#PC00190;protein modifying enzyme#PC00260 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489;Parkinson disease#P00049>20S proteasome#P01227 CIOIN|Ensembl=ENSCING00000014887.2|UniProtKB=F6XBP2 F6XBP2 PTHR10082:SF60 INTEGRIN BETA SUBUNIT INTEGRIN BETA-PS cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;integrin binding#GO:0005178;binding#GO:0005488;signaling receptor binding#GO:0005102 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cell adhesion mediated by integrin#GO:0033627;cell-cell adhesion#GO:0098609;cell motility#GO:0048870;cell adhesion#GO:0007155;cell communication#GO:0007154;cell-substrate adhesion#GO:0031589;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cell-matrix adhesion#GO:0007160;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;integrin-mediated signaling pathway#GO:0007229;cell migration#GO:0016477;signaling#GO:0023052 receptor complex#GO:0043235;membrane protein complex#GO:0098796;cell surface#GO:0009986;protein-containing complex#GO:0032991;plasma membrane signaling receptor complex#GO:0098802;anchoring junction#GO:0070161;plasma membrane protein complex#GO:0098797;focal adhesion#GO:0005925;cell junction#GO:0030054;cell-substrate junction#GO:0030055;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cell adhesion molecule#PC00069;integrin#PC00126 Integrin signalling pathway#P00034>Integrin beta#P00931 CIOIN|Ensembl=ENSCING00000005224.3|UniProtKB=F6XVF3 F6XVF3 PTHR11668:SF496 SERINE/THREONINE PROTEIN PHOSPHATASE SERINE_THREONINE-PROTEIN PHOSPHATASE protein phosphatase#PC00195;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000020384.1|UniProtKB=H2XM31 H2XM31 LOC100181200 PTHR11604:SF2 PROFILIN PROFILIN-4 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;actin binding#GO:0003779;binding#GO:0005488;actin monomer binding#GO:0003785 negative regulation of protein polymerization#GO:0032272;cellular localization#GO:0051641;negative regulation of biological process#GO:0048519;macromolecule localization#GO:0033036;regulation of cellular component organization#GO:0051128;regulation of actin polymerization or depolymerization#GO:0008064;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;regulation of protein-containing complex assembly#GO:0043254;regulation of biological quality#GO:0065008;regulation of cellular component biogenesis#GO:0044087;negative regulation of organelle organization#GO:0010639;regulation of actin cytoskeleton organization#GO:0032956;regulation of actin filament-based process#GO:0032970;negative regulation of cellular component organization#GO:0051129;regulation of protein polymerization#GO:0032271;negative regulation of cellular process#GO:0048523;regulation of anatomical structure size#GO:0090066;regulation of actin filament length#GO:0030832;regulation of organelle organization#GO:0033043;regulation of actin filament organization#GO:0110053;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of actin filament polymerization#GO:0030833;regulation of cellular component size#GO:0032535;protein localization#GO:0008104;negative regulation of supramolecular fiber organization#GO:1902904;regulation of supramolecular fiber organization#GO:1902903;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;maintenance of location#GO:0051235;regulation of cellular process#GO:0050794;maintenance of location in cell#GO:0051651;negative regulation of actin filament polymerization#GO:0030837;biological regulation#GO:0065007;negative regulation of protein-containing complex assembly#GO:0031333;negative regulation of cytoskeleton organization#GO:0051494 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;cell cortex#GO:0005938;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165 CIOIN|Ensembl=ENSCING00000004316.3|UniProtKB=Q1RLF0 Q1RLF0 Ci-ZF(TRAF_RING)-2 PTHR10131:SF94 TNF RECEPTOR ASSOCIATED FACTOR TNF RECEPTOR-ASSOCIATED FACTOR 4 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000009026.3|UniProtKB=F6R801 F6R801 PTHR10155:SF32 PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT LP02169P enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207 lipid metabolic process#GO:0006629;phospholipid biosynthetic process#GO:0008654;organophosphate biosynthetic process#GO:0090407;phosphatidylinositol biosynthetic process#GO:0006661;glycerolipid biosynthetic process#GO:0045017;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;phosphatidylinositol metabolic process#GO:0046488;glycerophospholipid metabolic process#GO:0006650;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;phosphatidylinositol phosphate biosynthetic process#GO:0046854;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;glycerophospholipid biosynthetic process#GO:0046474;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;phosphatidylinositol 3-kinase complex#GO:0005942;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;membrane#GO:0016020;transferase complex, transferring phosphorus-containing groups#GO:0061695;extrinsic component of membrane#GO:0019898 kinase modulator#PC00140 CIOIN|Ensembl=ENSCING00000008659.3|UniProtKB=F6ZY26 F6ZY26 PTHR14859:SF1 CALCOFLUOR WHITE HYPERSENSITIVE PROTEIN PRECURSOR PGAP2-INTERACTING PROTEIN lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;phospholipid biosynthetic process#GO:0008654;macromolecule modification#GO:0043412;organophosphate biosynthetic process#GO:0090407;phosphatidylinositol biosynthetic process#GO:0006661;glycolipid metabolic process#GO:0006664;protein modification process#GO:0036211;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;lipid biosynthetic process#GO:0008610;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;protein lipidation#GO:0006497;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;glycerolipid biosynthetic process#GO:0045017;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;glycerophospholipid metabolic process#GO:0006650;phosphatidylinositol metabolic process#GO:0046488;organic substance biosynthetic process#GO:1901576;liposaccharide metabolic process#GO:1903509;cellular process#GO:0009987;GPI anchor metabolic process#GO:0006505;membrane lipid biosynthetic process#GO:0046467;lipoprotein biosynthetic process#GO:0042158;primary metabolic process#GO:0044238;GPI anchor biosynthetic process#GO:0006506;carbohydrate derivative biosynthetic process#GO:1901137;membrane lipid metabolic process#GO:0006643;glycerophospholipid biosynthetic process#GO:0046474;glycolipid biosynthetic process#GO:0009247;organophosphate metabolic process#GO:0019637;lipoprotein metabolic process#GO:0042157;cellular lipid metabolic process#GO:0044255 CIOIN|Ensembl=ENSCING00000013894.2|UniProtKB=F6Q1C2 F6Q1C2 PTHR42757:SF32 IGLON FAMILY OF IMMUNOGLOBULIN SUPERFAMILY-RELATED PROTEIN AMALGAM defense/immunity protein#PC00090;immunoglobulin#PC00123 CIOIN|Ensembl=ENSCING00000003612.3|UniProtKB=F6U8W0 F6U8W0 PTHR12931:SF15 UBIQUITIN THIOLESTERASE PROTEIN OTUB UBIQUITIN THIOESTERASE OTUBAIN-LIKE cysteine-type peptidase activity#GO:0008234;ubiquitin-like protein peptidase activity#GO:0019783;ubiquitin-like protein binding#GO:0032182;binding#GO:0005488;catalytic activity#GO:0003824;ubiquitin binding#GO:0043130;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;protein binding#GO:0005515;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;cysteine-type deubiquitinase activity#GO:0004843 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;protein K48-linked deubiquitination#GO:0071108;protein modification by small protein removal#GO:0070646;protein deubiquitination#GO:0016579;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;post-translational protein modification#GO:0043687;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cysteine protease#PC00081;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000007399.3|UniProtKB=F6RZ17 F6RZ17 LOC100184920 PTHR12764:SF4 WD REPEAT DOMAIN-RELATED INTRAFLAGELLAR TRANSPORT PROTEIN 122 HOMOLOG non-motile cilium assembly#GO:1905515;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;cell projection organization#GO:0030030;macromolecule localization#GO:0033036;transport#GO:0006810;microtubule-based movement#GO:0007018;plasma membrane bounded cell projection organization#GO:0120036;protein localization to cilium#GO:0061512;establishment of localization#GO:0051234;cytoskeleton-dependent intracellular transport#GO:0030705;protein localization to organelle#GO:0033365;cellular component assembly#GO:0022607;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cellular process#GO:0009987;intraciliary retrograde transport#GO:0035721;transport along microtubule#GO:0010970;intraciliary transport#GO:0042073;cell projection assembly#GO:0030031;protein localization#GO:0008104;organelle assembly#GO:0070925;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;microtubule-based transport#GO:0099111;cellular macromolecule localization#GO:0070727;microtubule-based process#GO:0007017;organelle organization#GO:0006996;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;protein-containing complex localization#GO:0031503 protein-containing complex#GO:0032991;non-motile cilium#GO:0097730;intraciliary transport particle A#GO:0030991;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cilium#GO:0005929;intraciliary transport particle#GO:0030990 CIOIN|Ensembl=ENSCING00000022911.1|UniProtKB=H2XRG4 H2XRG4 PTHR21818:SF0 BC025462 PROTEIN FANCONI ANEMIA GROUP I PROTEIN enzyme binding#GO:0019899;protein binding#GO:0005515;binding#GO:0005488 CIOIN|Ensembl=ENSCING00000024131.1|UniProtKB=H2Y2K2 H2Y2K2 LOC100183174 PTHR12176:SF78 SAM-DEPENDENT METHYLTRANSFERASE SUPERFAMILY PROTEIN EEF1A LYSINE AND N-TERMINAL METHYLTRANSFERASE methyltransferase#PC00155 CIOIN|Ensembl=ENSCING00000021107.1|UniProtKB=H2XUD3 H2XUD3 LOC100179539 PTHR47664:SF1 NLPC_P60 DOMAIN-CONTAINING PROTEIN CHROMOSOME UNDETERMINED SCAFFOLD_14, WHOLE GENOME SHOTGUN SEQUENCE CIOIN|Ensembl=ENSCING00000007623.3|UniProtKB=F6XN27 F6XN27 PTHR11254:SF67 HECT DOMAIN UBIQUITIN-PROTEIN LIGASE E3 UBIQUITIN-PROTEIN LIGASE HUWE1 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;protein polyubiquitination#GO:0000209;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E3#P01490 CIOIN|Ensembl=ENSCING00000011319.2|UniProtKB=F6XIW9 F6XIW9 PTHR24254:SF11 PROTHROMBIN SUBFAMILY NOT NAMED serine protease#PC00203;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000019162.1|UniProtKB=H2XSJ8 H2XSJ8 LOC100184077 PTHR13455:SF7 TRANSCRIPTIONAL REPRESSOR P66-RELATED SIMJANG, ISOFORM E negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of biosynthetic process#GO:0009890;negative regulation of RNA metabolic process#GO:0051253;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;ATPase complex#GO:1904949;intracellular organelle lumen#GO:0070013;SWI/SNF superfamily-type complex#GO:0070603;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;chromosome#GO:0005694;histone deacetylase complex#GO:0000118;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 DNA-binding transcription factor#PC00218 CIOIN|Ensembl=ENSCING00000002561.3|UniProtKB=F6UFD9 F6UFD9 LOC100180370 PTHR13338:SF4 UPF0240 PROTEIN NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX ASSEMBLY FACTOR 4 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrial respiratory chain complex I assembly#GO:0032981;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;mitochondrion organization#GO:0007005;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000004461.3|UniProtKB=F6U4J4 F6U4J4 LOC100184484 PTHR24221:SF636 ATP-BINDING CASSETTE SUB-FAMILY B BILE SALT EXPORT PUMP transmembrane transporter activity#GO:0022857;primary active transmembrane transporter activity#GO:0015399;ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 localization#GO:0051179;cellular process#GO:0009987;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810 plasma membrane region#GO:0098590;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;apical part of cell#GO:0045177;plasma membrane#GO:0005886;apical plasma membrane#GO:0016324 ATP-binding cassette (ABC) transporter#PC00003;transporter#PC00227 CIOIN|Ensembl=ENSCING00000002852.3|UniProtKB=F6TN12 F6TN12 PTHR42985:SF45 SODIUM-COUPLED MONOCARBOXYLATE TRANSPORTER SODIUM_IODIDE COTRANSPORTER-LIKE symporter activity#GO:0015293;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 localization#GO:0051179;monoatomic cation transport#GO:0006812;sodium ion transport#GO:0006814;metal ion transport#GO:0030001;establishment of localization#GO:0051234;monoatomic ion transport#GO:0006811;transport#GO:0006810 secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000003602.3|UniProtKB=F6UY31 F6UY31 PTHR48125:SF12 LP07818P1 AT HOOK TRANSCRIPTION FACTOR FAMILY-RELATED Huntington disease#P00029>N-Wasp#P00769;Cytoskeletal regulation by Rho GTPase#P00016>N-WASP#P00525 CIOIN|Ensembl=ENSCING00000012750.2|UniProtKB=F7A8K6 F7A8K6 LOC100187118 PTHR23354:SF131 NUCLEOLAR PROTEIN 7/ESTROGEN RECEPTOR COACTIVATOR-RELATED MTOR-ASSOCIATED PROTEIN MEAK7 response to stimulus#GO:0050896;response to oxidative stress#GO:0006979;response to stress#GO:0006950 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000005886.2|UniProtKB=F6T4U7 F6T4U7 LOC100181505 PTHR14624:SF0 DFG10 PROTEIN POLYPRENOL REDUCTASE oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;macromolecule modification#GO:0043412;alcohol biosynthetic process#GO:0046165;protein modification process#GO:0036211;organic hydroxy compound biosynthetic process#GO:1901617;lipid catabolic process#GO:0016042;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;nitrogen compound metabolic process#GO:0006807;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;cellular lipid catabolic process#GO:0044242;glycoprotein metabolic process#GO:0009100;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;organic hydroxy compound metabolic process#GO:1901615;isoprenoid catabolic process#GO:0008300;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein glycosylation#GO:0006486;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;alcohol metabolic process#GO:0006066;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;isoprenoid metabolic process#GO:0006720;primary metabolic process#GO:0044238;isoprenoid biosynthetic process#GO:0008299;carbohydrate derivative biosynthetic process#GO:1901137;small molecule catabolic process#GO:0044282;protein N-linked glycosylation#GO:0006487;small molecule biosynthetic process#GO:0044283;cellular lipid metabolic process#GO:0044255;glycosylation#GO:0070085;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000006264.3|UniProtKB=F6VQ38 F6VQ38 PTHR19444:SF13 UNC-93 RELATED PROTEIN UNC-93 HOMOLOG A membrane-bound signaling molecule#PC00152 CIOIN|Ensembl=ENSCING00000023405.1|UniProtKB=H2XRW3 H2XRW3 PTHR11929:SF145 ALPHA- 1,3 -FUCOSYLTRANSFERASE ALPHA-(1,3)-FUCOSYLTRANSFERASE FUT-1 transferase activity#GO:0016740;fucosyltransferase activity#GO:0008417;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 glycosylation#GO:0070085;metabolic process#GO:0008152 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000019707.1|UniProtKB=H2XT92 H2XT92 PTHR12864:SF49 RAN BINDING PROTEIN 9-RELATED RAN-BINDING PROTEINS 9_10 HOMOLOG cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cellular process#GO:0009987;organelle organization#GO:0006996 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000014534.2|UniProtKB=F6WLI0 F6WLI0 PTHR43651:SF3 1,4-ALPHA-GLUCAN-BRANCHING ENZYME 1,4-ALPHA-GLUCAN-BRANCHING ENZYME transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 carbohydrate metabolic process#GO:0005975;organic substance metabolic process#GO:0071704;primary metabolic process#GO:0044238;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 amylase#PC00048;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000008918.4|UniProtKB=F7BE59 F7BE59 PTHR18871:SF2 CENTROSOMAL PROTEIN OF 112 KDA CENTROSOMAL PROTEIN OF 112 KDA CIOIN|Ensembl=ENSCING00000021495.1|UniProtKB=H2XZM9 H2XZM9 PTHR22588:SF3 VWFA DOMAIN-CONTAINING PROTEIN VWFA DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000004274.3|UniProtKB=F6TTI3 F6TTI3 PTHR43982:SF1 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 14 cysteine-type peptidase activity#GO:0008234;ubiquitin-like protein peptidase activity#GO:0019783;proteasome binding#GO:0070628;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;protein-containing complex binding#GO:0044877;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;cysteine-type deubiquitinase activity#GO:0004843 regulation of proteolysis#GO:0030162;regulation of protein metabolic process#GO:0051246;protein modification by small protein conjugation or removal#GO:0070647;regulation of catabolic process#GO:0009894;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;regulation of nitrogen compound metabolic process#GO:0051171;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;regulation of protein catabolic process#GO:0042176;regulation of proteolysis involved in protein catabolic process#GO:1903050;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;regulation of proteasomal protein catabolic process#GO:0061136;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule metabolic process#GO:0060255;nitrogen compound metabolic process#GO:0006807;protein modification by small protein removal#GO:0070646;biological regulation#GO:0065007;protein deubiquitination#GO:0016579;protein metabolic process#GO:0019538;regulation of metabolic process#GO:0019222;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cysteine protease#PC00081;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000001695.3|UniProtKB=F6UJD6 F6UJD6 PTHR13634:SF0 RIBOSOME BIOGENESIS PROTEIN BRIX RIBOSOME BIOGENESIS PROTEIN BRX1 HOMOLOG nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;cellular process#GO:0009987;ribosomal large subunit biogenesis#GO:0042273;organelle assembly#GO:0070925;protein-RNA complex assembly#GO:0022618;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;organelle organization#GO:0006996;ribosomal large subunit assembly#GO:0000027;ribonucleoprotein complex biogenesis#GO:0022613;protein-RNA complex organization#GO:0071826;ribosome biogenesis#GO:0042254;non-membrane-bounded organelle assembly#GO:0140694 intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000012938.2|UniProtKB=F6RH73 F6RH73 PTHR45617:SF181 LEUCINE RICH REPEAT FAMILY PROTEIN LP04042P scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000005741.3|UniProtKB=F6Q062 F6Q062 PTHR24418:SF460 TYROSINE-PROTEIN KINASE PROTEIN KINASE DOMAIN-CONTAINING PROTEIN protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;non-membrane spanning protein tyrosine kinase activity#GO:0004715;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 non-receptor tyrosine protein kinase#PC00168 CIOIN|Ensembl=ENSCING00000009644.3|UniProtKB=F6XHV4 F6XHV4 PTHR24276:SF98 POLYSERASE-RELATED FI18310P1-RELATED serine protease#PC00203;protease#PC00190 CIOIN|Ensembl=ENSCING00000008705.3|UniProtKB=F6WCV2 F6WCV2 PTHR11909:SF7 CASEIN KINASE-RELATED CELL DIVISION CYCLE 7-RELATED PROTEIN KINASE transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;double-strand break repair#GO:0006302;macromolecule modification#GO:0043412;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;peptidyl-serine phosphorylation#GO:0018105;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;recombinational repair#GO:0000725;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;double-strand break repair via homologous recombination#GO:0000724;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;double-strand break repair via break-induced replication#GO:0000727;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 CIOIN|Ensembl=ENSCING00000007998.3|UniProtKB=A0A1W3JNK5 A0A1W3JNK5 LOC100185231 PTHR12507:SF3 REDUCED GROWTH PHENOTYPE 1 RGP1, YEAST -RELATED RAB6A-GEF COMPLEX PARTNER PROTEIN 2 localization#GO:0051179;endosomal transport#GO:0016197;cellular localization#GO:0051641;establishment of localization#GO:0051234;transport#GO:0006810;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;cellular process#GO:0009987;cytosolic transport#GO:0016482;retrograde transport, endosome to Golgi#GO:0042147 bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;organelle membrane#GO:0031090;intracellular protein-containing complex#GO:0140535;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;Golgi membrane#GO:0000139;guanyl-nucleotide exchange factor complex#GO:0032045 CIOIN|Ensembl=ENSCING00000001859.3|UniProtKB=F7AKV1 F7AKV1 LOC100185031 PTHR11977:SF123 VILLIN GELSOLIN cytoskeletal protein binding#GO:0008092;phosphatidylinositol bisphosphate binding#GO:1902936;small molecule binding#GO:0036094;phosphatidylinositol-4,5-bisphosphate binding#GO:0005546;binding#GO:0005488;actin filament binding#GO:0051015;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;lipid binding#GO:0008289;ion binding#GO:0043167;phosphatidylinositol binding#GO:0035091;anion binding#GO:0043168;phosphatidylinositol phosphate binding#GO:1901981;phospholipid binding#GO:0005543;actin binding#GO:0003779 negative regulation of protein polymerization#GO:0032272;negative regulation of protein depolymerization#GO:1901880;negative regulation of biological process#GO:0048519;negative regulation of actin filament depolymerization#GO:0030835;regulation of cellular component organization#GO:0051128;regulation of actin polymerization or depolymerization#GO:0008064;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;actin filament-based process#GO:0030029;regulation of protein-containing complex assembly#GO:0043254;regulation of biological quality#GO:0065008;regulation of cellular component biogenesis#GO:0044087;supramolecular fiber organization#GO:0097435;negative regulation of organelle organization#GO:0010639;negative regulation of protein-containing complex disassembly#GO:0043242;actin filament organization#GO:0007015;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;regulation of actin filament-based process#GO:0032970;barbed-end actin filament capping#GO:0051016;negative regulation of cellular component organization#GO:0051129;regulation of protein polymerization#GO:0032271;negative regulation of cellular process#GO:0048523;regulation of anatomical structure size#GO:0090066;regulation of actin filament length#GO:0030832;regulation of organelle organization#GO:0033043;regulation of actin filament organization#GO:0110053;actin polymerization or depolymerization#GO:0008154;regulation of protein-containing complex disassembly#GO:0043244;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of actin filament polymerization#GO:0030833;regulation of cellular component size#GO:0032535;negative regulation of supramolecular fiber organization#GO:1902904;regulation of supramolecular fiber organization#GO:1902903;cellular component organization or biogenesis#GO:0071840;regulation of protein depolymerization#GO:1901879;organelle organization#GO:0006996;regulation of actin filament depolymerization#GO:0030834;regulation of cellular process#GO:0050794;negative regulation of actin filament polymerization#GO:0030837;biological regulation#GO:0065007;negative regulation of protein-containing complex assembly#GO:0031333;actin cytoskeleton organization#GO:0030036;negative regulation of cytoskeleton organization#GO:0051494 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-motor actin binding protein#PC00165 FAS signaling pathway#P00020>Gelsolin#P00611 CIOIN|Ensembl=ENSCING00000018731.1|UniProtKB=H2XUD0 H2XUD0 PTHR19443:SF16 HEXOKINASE HEXOKINASE TYPE 1-RELATED transferase activity, transferring phosphorus-containing groups#GO:0016772;carbohydrate kinase activity#GO:0019200;transferase activity#GO:0016740;hexokinase activity#GO:0004396;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301 monosaccharide metabolic process#GO:0005996;carbohydrate phosphorylation#GO:0046835;cellular metabolic process#GO:0044237;phosphorylation#GO:0016310;hexose metabolic process#GO:0019318;cellular process#GO:0009987;carbohydrate metabolic process#GO:0005975;glucose metabolic process#GO:0006006;phosphorus metabolic process#GO:0006793;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704 kinase#PC00137 Pentose phosphate pathway#P02762>Hexokinase#P03079;Glycolysis#P00024>Hexokinase#P00677;Fructose galactose metabolism#P02744>Hexokinase#P02966 CIOIN|Ensembl=ENSCING00000017405.2|UniProtKB=Q1RPW9 Q1RPW9 Ci-ZF(FYVE)-1 PTHR46189:SF1 LD41958P LD41958P cytoplasm#GO:0005737;endosome#GO:0005768;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000016233.2|UniProtKB=Q1RLH3 Q1RLH3 Ci-ZF(C2H2)-56 PTHR24390:SF235 ZINC FINGER PROTEIN GH09339P-RELATED sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 CIOIN|Ensembl=ENSCING00000018127.1|UniProtKB=H2Y2R1 H2Y2R1 PTHR16165:SF5 NXPE FAMILY MEMBER NXPE FAMILY MEMBER 3 CIOIN|Ensembl=ENSCING00000005206.3|UniProtKB=F6Z188 F6Z188 LOC100176196 PTHR46207:SF1 PROTEIN RCC2 PROTEIN RCC2 enzyme binding#GO:0019899;protein binding#GO:0005515;small GTPase binding#GO:0031267;binding#GO:0005488 regulation of biological process#GO:0050789;negative regulation of hydrolase activity#GO:0051346;negative regulation of biological process#GO:0048519;regulation of molecular function#GO:0065009;regulation of GTPase activity#GO:0043087;biological regulation#GO:0065007;regulation of hydrolase activity#GO:0051336;regulation of catalytic activity#GO:0050790;negative regulation of catalytic activity#GO:0043086;negative regulation of molecular function#GO:0044092 cellular anatomical entity#GO:0110165;membrane#GO:0016020 CIOIN|Ensembl=ENSCING00000013958.2|UniProtKB=F6RPN1 F6RPN1 PTHR24060:SF166 METABOTROPIC GLUTAMATE RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 3 PROFILE DOMAIN-CONTAINING PROTEIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;adenylate cyclase inhibiting G protein-coupled glutamate receptor activity#GO:0001640;G protein-coupled receptor activity#GO:0004930;glutamate receptor activity#GO:0008066;transmembrane signaling receptor activity#GO:0004888 regulation of cell communication#GO:0010646;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of signaling#GO:0023051;cell communication#GO:0007154;cellular process#GO:0009987;glutamate receptor signaling pathway#GO:0007215;regulation of synaptic transmission, glutamatergic#GO:0051966;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;modulation of chemical synaptic transmission#GO:0050804;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 CIOIN|Ensembl=ENSCING00000016067.2|UniProtKB=F6W5N3 F6W5N3 PTHR23503:SF8 SOLUTE CARRIER FAMILY 2 FACILITATED GLUCOSE TRANSPORTER PROTEIN 1 transmembrane transporter activity#GO:0022857;sugar transmembrane transporter activity#GO:0051119;transporter activity#GO:0005215;carbohydrate transmembrane transporter activity#GO:0015144 localization#GO:0051179;organic substance transport#GO:0071702;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810;cellular process#GO:0009987;carbohydrate transmembrane transport#GO:0034219;carbohydrate transport#GO:0008643 cellular anatomical entity#GO:0110165;membrane#GO:0016020 secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000023238.1|UniProtKB=H2XP28 H2XP28 PTHR24372:SF77 GLYCOPROTEIN HORMONE RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 response to organic substance#GO:0010033;positive regulation of adenylate cyclase activity#GO:0045762;regulation of lyase activity#GO:0051339;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;cellular response to stimulus#GO:0051716;regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;cellular response to endogenous stimulus#GO:0071495;cellular response to chemical stimulus#GO:0070887;positive regulation of catalytic activity#GO:0043085;cellular response to organic substance#GO:0071310;regulation of cyclase activity#GO:0031279;positive regulation of molecular function#GO:0044093;cell communication#GO:0007154;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;positive regulation of cyclase activity#GO:0031281;hormone-mediated signaling pathway#GO:0009755;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to endogenous stimulus#GO:0009719;response to hormone#GO:0009725;cellular response to hormone stimulus#GO:0032870;response to chemical#GO:0042221;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of lyase activity#GO:0051349;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 CIOIN|Ensembl=ENSCING00000001156.2|UniProtKB=Q4H336 Q4H336 Ci-noggin PTHR10494:SF16 BONE MORPHOGENETIC PROTEIN INHIBITOR, NOGGIN NOGGIN-2-LIKE regulation of cell communication#GO:0010646;cellular developmental process#GO:0048869;negative regulation of biological process#GO:0048519;negative regulation of response to stimulus#GO:0048585;ossification#GO:0001503;regionalization#GO:0003002;developmental process#GO:0032502;multicellular organism development#GO:0007275;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;osteoblast differentiation#GO:0001649;dorsal/ventral pattern formation#GO:0009953;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of BMP signaling pathway#GO:0030510;cell differentiation#GO:0030154;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;negative regulation of BMP signaling pathway#GO:0030514;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cellular response to growth factor stimulus#GO:0090287;multicellular organismal process#GO:0032501;negative regulation of signal transduction#GO:0009968;pattern specification process#GO:0007389;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 intercellular signal molecule#PC00207 CIOIN|Ensembl=ENSCING00000009415.3|UniProtKB=F6TLP7 F6TLP7 PTHR16052:SF0 TBCC DOMAIN-CONTAINING PROTEIN 1 TBCC DOMAIN-CONTAINING PROTEIN 1 CIOIN|Ensembl=ENSCING00000000407.3|UniProtKB=Q9U6V0 Q9U6V0 Ci-Wnt5 PTHR12027:SF77 WNT RELATED PROTEIN WNT-5 molecular function activator activity#GO:0140677;binding#GO:0005488;molecular function regulator activity#GO:0098772;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;cytokine activity#GO:0005125;G protein-coupled receptor binding#GO:0001664;signaling receptor binding#GO:0005102 cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;neurogenesis#GO:0022008;developmental process#GO:0032502;multicellular organism development#GO:0007275;cell communication#GO:0007154;cell fate commitment#GO:0045165;cell-cell signaling by wnt#GO:0198738;nervous system development#GO:0007399;cellular process#GO:0009987;regulation of biological process#GO:0050789;system development#GO:0048731;response to stimulus#GO:0050896;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;neuron differentiation#GO:0030182;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;cell-cell signaling#GO:0007267;signaling#GO:0023052;canonical Wnt signaling pathway#GO:0060070;Wnt signaling pathway#GO:0016055 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 intercellular signal molecule#PC00207 Wnt signaling pathway#P00057>Wnt#P01444;Alzheimer disease-presenilin pathway#P00004>Wnt#P00142;Angiogenesis#P00005>Wnt#P00206;Cadherin signaling pathway#P00012>Wnt#P00474 CIOIN|Ensembl=ENSCING00000004499.3|UniProtKB=F6TF00 F6TF00 LOC100178286 PTHR23320:SF165 MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MS4A -RELATED MARVEL DOMAIN-CONTAINING PROTEIN transporter#PC00227 CIOIN|Ensembl=ENSCING00000004529.3|UniProtKB=F7A967 F7A967 LOC100184172 PTHR14014:SF0 TELOMERE REPEATS-BINDING BOUQUET FORMATION PROTEIN 1 TELOMERE REPEATS-BINDING BOUQUET FORMATION PROTEIN 1 cellular localization#GO:0051641;organelle localization#GO:0051640;homologous chromosome segregation#GO:0045143;nuclear division#GO:0000280;cell cycle process#GO:0022402;chromosome segregation#GO:0007059;chromosome organization involved in meiotic cell cycle#GO:0070192;establishment of localization#GO:0051234;meiotic cell cycle process#GO:1903046;meiosis I cell cycle process#GO:0061982;reproductive process#GO:0022414;establishment of organelle localization#GO:0051656;meiosis I#GO:0007127;nuclear chromosome segregation#GO:0098813;establishment of chromosome localization#GO:0051303;meiotic cell cycle#GO:0051321;homologous chromosome pairing at meiosis#GO:0007129;cellular component organization#GO:0016043;cellular process#GO:0009987;meiotic chromosome segregation#GO:0045132;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;telomere localization#GO:0034397;reproduction#GO:0000003;chromosome organization#GO:0051276;organelle organization#GO:0006996;meiotic nuclear division#GO:0140013;sexual reproduction#GO:0019953;establishment of localization in cell#GO:0051649;organelle fission#GO:0048285;cell cycle#GO:0007049;chromosome localization#GO:0050000 CIOIN|Ensembl=ENSCING00000014408.2|UniProtKB=F6ZWT9 F6ZWT9 PTHR14388:SF17 T CELL-SPECIFIC ADAPTER PROTEIN TSAD SH2 DOMAIN-CONTAINING PROTEIN cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 defense/immunity protein#PC00090 CIOIN|Ensembl=ENSCING00000002865.3|UniProtKB=F6T060 F6T060 LOC100185939 PTHR43272:SF107 LONG-CHAIN-FATTY-ACID--COA LIGASE LONG-CHAIN-FATTY-ACID--COA LIGASE 5 long-chain fatty acid-CoA ligase activity#GO:0004467;ligase activity#GO:0016874;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ligase#PC00142;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000000293.3|UniProtKB=F6ZZH3 F6ZZH3 PTHR23326:SF1 CCR4 NOT-RELATED CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 3 negative regulation of gene expression#GO:0010629;regulation of catabolic process#GO:0009894;heterocycle catabolic process#GO:0046700;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;nucleobase-containing compound metabolic process#GO:0006139;RNA destabilization#GO:0050779;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;regulation of RNA stability#GO:0043487;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;nuclear-transcribed mRNA poly(A) tail shortening#GO:0000289;positive regulation of mRNA catabolic process#GO:0061014;regulation of cellular process#GO:0050794;post-transcriptional regulation of gene expression#GO:0010608;positive regulation of catabolic process#GO:0009896;mRNA destabilization#GO:0061157;nucleobase-containing compound catabolic process#GO:0034655;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;regulation of mRNA stability#GO:0043488;RNA metabolic process#GO:0016070;positive regulation of cellular catabolic process#GO:0031331;cellular nitrogen compound catabolic process#GO:0044270;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;mRNA catabolic process#GO:0006402;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;regulation of gene expression#GO:0010468;organic substance catabolic process#GO:1901575;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;positive regulation of mRNA metabolic process#GO:1903313;heterocycle metabolic process#GO:0046483;negative regulation of biosynthetic process#GO:0009890;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;positive regulation of RNA metabolic process#GO:0051254 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;protein-containing complex#GO:0032991;P-body#GO:0000932;CCR4-NOT complex#GO:0030014;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464;intracellular anatomical structure#GO:0005622 general transcription factor#PC00259 CIOIN|Ensembl=ENSCING00000009236.3|UniProtKB=F6W1D2 F6W1D2 LOC100184384 PTHR23074:SF78 AAA DOMAIN-CONTAINING KATANIN P60 ATPASE-CONTAINING SUBUNIT A-LIKE 2 pyrophosphatase activity#GO:0016462;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;ATP hydrolysis activity#GO:0016887 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 CIOIN|Ensembl=ENSCING00000007136.3|UniProtKB=F6S902 F6S902 LOC113473986 PTHR11804:SF79 PROTEASE M3 THIMET OLIGOPEPTIDASE-RELATED MITOCHONDRIAL INTERMEDIATE PEPTIDASE hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;peptide metabolic process#GO:0006518;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000002595.3|UniProtKB=Q6XV77 Q6XV77 rhag PTHR11730:SF60 AMMONIUM TRANSPORTER RH50, ISOFORM D inorganic molecular entity transmembrane transporter activity#GO:0015318;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;inorganic cation transmembrane transporter activity#GO:0022890;channel activity#GO:0015267 localization#GO:0051179;inorganic ion homeostasis#GO:0098771;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;nitrogen compound transport#GO:0071705;homeostatic process#GO:0042592;inorganic ion transmembrane transport#GO:0098660;chemical homeostasis#GO:0048878;cellular process#GO:0009987 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 primary active transporter#PC00068;transporter#PC00227 CIOIN|Ensembl=ENSCING00000004845.3|UniProtKB=F6TYS5 F6TYS5 PTHR45625:SF4 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-RELATED PEPTIDYLPROLYL ISOMERASE DOMAIN AND WD REPEAT-CONTAINING PROTEIN 1 peptidyl-prolyl cis-trans isomerase activity#GO:0003755;isomerase activity#GO:0016853;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;protein peptidyl-prolyl isomerization#GO:0000413;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 chaperone#PC00072 CIOIN|Ensembl=ENSCING00000024093.1|UniProtKB=H2Y399 H2Y399 LOC100185713 PTHR39297:SF1 CUB DOMAIN-CONTAINING PROTEIN CUB DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000022207.1|UniProtKB=F7AWL5 F7AWL5 PTHR10706:SF130 F-BOX FAMILY PROTEIN F-BOX ONLY PROTEIN 31 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000003162.3|UniProtKB=F6QEE3 F6QEE3 LOC100178248 PTHR43550:SF3 3-KETODIHYDROSPHINGOSINE REDUCTASE 3-KETODIHYDROSPHINGOSINE REDUCTASE reductase#PC00198;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000009336.3|UniProtKB=F6Z419 F6Z419 LOC448996 PTHR23349:SF72 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, TWIST HLH54F sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 basic helix-loop-helix transcription factor#PC00055 CIOIN|Ensembl=ENSCING00000010498.3|UniProtKB=F6S3S9 F6S3S9 LOC100178536 PTHR10687:SF2 SECRETORY CARRIER-ASSOCIATED MEMBRANE PROTEIN SCAMP SECRETORY CARRIER-ASSOCIATED MEMBRANE PROTEIN localization#GO:0051179;organic substance transport#GO:0071702;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;transport#GO:0006810;protein transport#GO:0015031;nitrogen compound transport#GO:0071705;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104 bounding membrane of organelle#GO:0098588;trans-Golgi network#GO:0005802;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;trans-Golgi network membrane#GO:0032588;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;recycling endosome membrane#GO:0055038;organelle#GO:0043226;endosome membrane#GO:0010008;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;recycling endosome#GO:0055037;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791;cytoplasmic vesicle membrane#GO:0030659 transfer/carrier protein#PC00219 CIOIN|Ensembl=ENSCING00000013997.2|UniProtKB=F6RDQ7 F6RDQ7 PTHR12968:SF4 B9 DOMAIN-CONTAINING TECTONIC-LIKE COMPLEX MEMBER MKS1 organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cell projection organization#GO:0030030;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031 protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;cilium#GO:0005929;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;ciliary transition zone#GO:0035869 structural protein#PC00211 CIOIN|Ensembl=ENSCING00000021643.1|UniProtKB=H2Y0N2 H2Y0N2 PTHR15744:SF0 BLOM7 KH HOMOLOGY DOMAIN-CONTAINING PROTEIN 4 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000004409.3|UniProtKB=F6YNT4 F6YNT4 PTHR10856:SF20 CORONIN CORONIN-7 cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165 CIOIN|Ensembl=ENSCING00000022955.1|UniProtKB=H2Y1C1 H2Y1C1 PTHR10887:SF419 DNA2/NAM7 HELICASE FAMILY RNA HELICASE MOV10L1 negative regulation of gene expression#GO:0010629;regulatory ncRNA-mediated gene silencing#GO:0031047;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of biosynthetic process#GO:0009890;negative regulation of metabolic process#GO:0009892;regulation of biological process#GO:0050789;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulatory ncRNA-mediated post-transcriptional gene silencing#GO:0035194;regulation of cellular process#GO:0050794;regulation of biosynthetic process#GO:0009889;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;P granule#GO:0043186;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464;intracellular anatomical structure#GO:0005622 RNA helicase#PC00032 CIOIN|Ensembl=ENSCING00000022590.1|UniProtKB=H2XMF4 H2XMF4 PTHR11240:SF22 RIBONUCLEASE T2 RIBONUCLEASE T2 endoribonuclease#PC00094;RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000008635.3|UniProtKB=F7AHC2 F7AHC2 PTHR11571:SF222 GLUTATHIONE S-TRANSFERASE GLUTATHIONE TRANSFERASE glutathione transferase activity#GO:0004364;transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824 sulfur compound metabolic process#GO:0006790;nitrogen compound metabolic process#GO:0006807;peptide metabolic process#GO:0006518;cellular modified amino acid metabolic process#GO:0006575;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular process#GO:0009987;glutathione metabolic process#GO:0006749;amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000022017.1|UniProtKB=H2Y1C2 H2Y1C2 PTHR24377:SF1012 IP01015P-RELATED C2H2-TYPE DOMAIN-CONTAINING PROTEIN-RELATED C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 CIOIN|Ensembl=ENSCING00000023228.1|UniProtKB=H2XQ36 H2XQ36 PTHR16950:SF16 ZINC TRANSPORTER SLC39A7 HISTIDINE-RICH MEMBRANE PROTEIN KE4 ZINC TRANSPORTER ZIP13 primary active transporter#PC00068;transporter#PC00227 CIOIN|Ensembl=ENSCING00000003395.4|UniProtKB=F6ZN98 F6ZN98 PTHR17695:SF11 SMALL SUBUNIT PROCESSOME COMPONENT 20 HOMOLOG SMALL SUBUNIT PROCESSOME COMPONENT 20 HOMOLOG membrane-enclosed lumen#GO:0031974;small-subunit processome#GO:0032040;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;nuclear lumen#GO:0031981;90S preribosome#GO:0030686 CIOIN|Ensembl=ENSCING00000004125.3|UniProtKB=F6V9G2 F6V9G2 PTHR13930:SF0 S-ADENOSYL-L-METHIONINE-DEPENDENT TRNA 4-DEMETHYLWYOSINE SYNTHASE S-ADENOSYL-L-METHIONINE-DEPENDENT TRNA 4-DEMETHYLWYOSINE SYNTHASE TYW1-RELATED lyase#PC00144 CIOIN|Ensembl=ENSCING00000013842.2|UniProtKB=H2XKS2 H2XKS2 PTHR24373:SF396 SLIT RELATED LEUCINE-RICH REPEAT NEURONAL PROTEIN LEUCINE RICH REPEATS AND IMMUNOGLOBULIN LIKE DOMAINS 1 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 transmembrane signal receptor#PC00197 CIOIN|Ensembl=ENSCING00000009796.3|UniProtKB=F6ZSL9 F6ZSL9 LOC100183156 PTHR32026:SF10 METHYLTRANSFERASE-LIKE PROTEIN 24 METHYLTRANSFERASE-LIKE PROTEIN 24-RELATED methyltransferase#PC00155 CIOIN|Ensembl=ENSCING00000024027.1|UniProtKB=H2XQQ4 H2XQQ4 PTHR46830:SF1 TRANSFERASE, PUTATIVE-RELATED ALPHA-1,4-N-ACETYLGLUCOSAMINYLTRANSFERASE transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000019936.1|UniProtKB=H2XVJ4 H2XVJ4 LOC100182480 PTHR11001:SF2 MITOCHONDRIAL FISSION PROCESS PROTEIN 1 MITOCHONDRIAL FISSION PROCESS PROTEIN 1 cellular component organization or biogenesis#GO:0071840;organelle fission#GO:0048285;mitochondrion organization#GO:0007005;cellular component organization#GO:0016043;cellular process#GO:0009987;organelle organization#GO:0006996;mitochondrial fission#GO:0000266 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000002259.3|UniProtKB=F6W2S7 F6W2S7 LOC100184593 PTHR43161:SF9 SORBITOL DEHYDROGENASE SORBITOL DEHYDROGENASE dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000018219.1|UniProtKB=H2Y2E0 H2Y2E0 LOC100187307 PTHR32026:SF10 METHYLTRANSFERASE-LIKE PROTEIN 24 METHYLTRANSFERASE-LIKE PROTEIN 24-RELATED methyltransferase#PC00155 CIOIN|Ensembl=ENSCING00000005707.3|UniProtKB=F6U2J1 F6U2J1 PTHR43651:SF3 1,4-ALPHA-GLUCAN-BRANCHING ENZYME 1,4-ALPHA-GLUCAN-BRANCHING ENZYME transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 carbohydrate metabolic process#GO:0005975;organic substance metabolic process#GO:0071704;primary metabolic process#GO:0044238;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 amylase#PC00048;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000007918.3|UniProtKB=F6V1A9 F6V1A9 PTHR12896:SF1 PAX6 NEIGHBOR PROTEIN PAXNEB ELONGATOR COMPLEX PROTEIN 4 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA modification#GO:0009451;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;tRNA modification#GO:0006400;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;tRNA wobble uridine modification#GO:0002098;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 elongator holoenzyme complex#GO:0033588;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;transcription elongation factor complex#GO:0008023;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 CIOIN|Ensembl=ENSCING00000003362.3|UniProtKB=F7BA12 F7BA12 PTHR48032:SF18 RNA-BINDING PROTEIN MUSASHI HOMOLOG RBP6 RRM DOMAIN-CONTAINING PROTEIN nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 regulation of protein metabolic process#GO:0051246;regulation of amide metabolic process#GO:0034248;regulation of nitrogen compound metabolic process#GO:0051171;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biosynthetic process#GO:0009889;post-transcriptional regulation of gene expression#GO:0010608;biological regulation#GO:0065007;regulation of translation#GO:0006417;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000001370.3|UniProtKB=F6S9V9 F6S9V9 PTHR24253:SF176 TRANSMEMBRANE PROTEASE SERINE CORIN, ISOFORM B serine protease#PC00203;protease#PC00190 CIOIN|Ensembl=ENSCING00000003032.3|UniProtKB=F6QA01 F6QA01 LOC100185651 PTHR22654:SF2 G PROTEIN PATHWAY SUPPRESSOR 2 G PROTEIN PATHWAY SUPPRESSOR 2 molecular adaptor activity#GO:0060090;transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;protein-macromolecule adaptor activity#GO:0030674 regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667 protein-binding activity modulator#PC00095 CIOIN|Ensembl=ENSCING00000006549.3|UniProtKB=F6RJA6 F6RJA6 PTHR11348:SF17 CONNECTIVE TISSUE GROWTH FACTOR-RELATED CCN carbohydrate derivative binding#GO:0097367;integrin binding#GO:0005178;binding#GO:0005488;heparin binding#GO:0008201;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;glycosaminoglycan binding#GO:0005539;signaling receptor binding#GO:0005102 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;positive regulation of cell differentiation#GO:0045597;cell communication#GO:0007154;cell adhesion#GO:0007155;cellular process#GO:0009987;regulation of cell differentiation#GO:0045595;positive regulation of developmental process#GO:0051094;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;biological regulation#GO:0065007;signaling#GO:0023052;positive regulation of biological process#GO:0048518 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;extracellular space#GO:0005615;extracellular region#GO:0005576 growth factor#PC00112 CIOIN|Ensembl=ENSCING00000008758.3|UniProtKB=F6T0A0 F6T0A0 PTHR45742:SF8 COMPLEMENT COMPONENT C6 FLOCCULATION PROTEIN FLO11 complement component#PC00078 CIOIN|Ensembl=ENSCING00000014352.2|UniProtKB=F6TYH2 F6TYH2 LOC100178130 PTHR10671:SF108 EPITHELIAL MEMBRANE PROTEIN-RELATED CLAUDIN FAMILY PROTEIN-RELATED cytoskeletal protein#PC00085 CIOIN|Ensembl=ENSCING00000007204.3|UniProtKB=F6Y7V1 F6Y7V1 LOC100175841 PTHR13513:SF9 E3 UBIQUITIN-PROTEIN LIGASE UBR7 E3 UBIQUITIN-PROTEIN LIGASE UBR7-RELATED cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000007365.3|UniProtKB=F6VZ53 F6VZ53 LOC100176087 PTHR31698:SF11 LYSOZYME G FAMILY MEMBER LYSOZYME G CIOIN|Ensembl=ENSCING00000006323.4|UniProtKB=L7N0S7 L7N0S7 ciatpsyna PTHR48082:SF2 ATP SYNTHASE SUBUNIT ALPHA, MITOCHONDRIAL ATP SYNTHASE SUBUNIT ALPHA, MITOCHONDRIAL monoatomic cation channel activity#GO:0005261;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;inorganic molecular entity transmembrane transporter activity#GO:0015318;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;proton channel activity#GO:0015252;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;channel activity#GO:0015267;ligase activity#GO:0016874;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;proton transmembrane transporter activity#GO:0015078;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;anion binding#GO:0043168;proton-transporting ATP synthase activity, rotational mechanism#GO:0046933;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;ATP binding#GO:0005524;monoatomic ion transmembrane transporter activity#GO:0015075 cellular aromatic compound metabolic process#GO:0006725;ribonucleoside triphosphate metabolic process#GO:0009199;nucleoside triphosphate metabolic process#GO:0009141;carbohydrate derivative metabolic process#GO:1901135;ATP biosynthetic process#GO:0006754;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ATP metabolic process#GO:0046034;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;purine nucleoside triphosphate biosynthetic process#GO:0009145;heterocycle metabolic process#GO:0046483;purine ribonucleoside triphosphate metabolic process#GO:0009205;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;ribonucleoside triphosphate biosynthetic process#GO:0009201;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;proton motive force-driven ATP synthesis#GO:0015986;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;nucleoside triphosphate biosynthetic process#GO:0009142;organophosphate metabolic process#GO:0019637;purine nucleoside triphosphate metabolic process#GO:0009144;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 ATP synthase#PC00002;primary active transporter#PC00068;transporter#PC00227 ATP synthesis#P02721>F1 alpha#P02791 CIOIN|Ensembl=ENSCING00000010674.3|UniProtKB=F6SD42 F6SD42 LOC100177692 PTHR31796:SF2 SUZ DOMAIN-CONTAINING PROTEIN 1 SUZ DOMAIN-CONTAINING PROTEIN 1 CIOIN|Ensembl=ENSCING00000024862.1|UniProtKB=H2XU15 H2XU15 PTHR46712:SF1 PHOSPHATIDYLGLYCEROPHOSPHATASE AND PROTEIN-TYROSINE PHOSPHATASE 1 PHOSPHATIDYLGLYCEROPHOSPHATASE AND PROTEIN-TYROSINE PHOSPHATASE 1 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 CIOIN|Ensembl=ENSCING00000023836.1|UniProtKB=H2XLK7 H2XLK7 LOC100187027 PTHR11753:SF6 ADAPTOR COMPLEXES SMALL SUBUNIT FAMILY AP-2 COMPLEX SUBUNIT SIGMA localization#GO:0051179;vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234;cellular process#GO:0009987;transport#GO:0006810 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 vesicle coat protein#PC00235 CIOIN|Gene=SYIM_CIOIN|UniProtKB=Q94425 Q94425 PTHR42765:SF1 SOLEUCYL-TRNA SYNTHETASE ISOLEUCINE--TRNA LIGASE, MITOCHONDRIAL catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;ligase activity#GO:0016874;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;peptide biosynthetic process#GO:0043043;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 aminoacyl-tRNA synthetase#PC00047;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000009344.3|UniProtKB=F6Z3S5 F6Z3S5 LOC100181703 PTHR42752:SF1 IMIDAZOLONEPROPIONASE IMIDAZOLONEPROPIONASE-RELATED hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides#GO:0016812;catalytic activity#GO:0003824 oxoacid metabolic process#GO:0043436;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;organic acid catabolic process#GO:0016054;amino acid catabolic process#GO:0009063;small molecule catabolic process#GO:0044282;nitrogen compound metabolic process#GO:0006807;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;carboxylic acid metabolic process#GO:0019752;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;cellular catabolic process#GO:0044248 metalloprotease#PC00153;protease#PC00190 CIOIN|Ensembl=ENSCING00000023871.1|UniProtKB=H2XRD0 H2XRD0 PTHR13348:SF0 RIBONUCLEASE P SUBUNIT P29 RIBONUCLEASE P PROTEIN SUBUNIT P29 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;endoribonuclease complex#GO:1902555;ribonuclease MRP complex#GO:0000172;ribonuclease P complex#GO:0030677;catalytic complex#GO:1902494;endonuclease complex#GO:1905348;intracellular protein-containing complex#GO:0140535;sno(s)RNA-containing ribonucleoprotein complex#GO:0005732 endoribonuclease#PC00094;RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000002375.3|UniProtKB=F6R5L0 F6R5L0 PTHR10210:SF57 RIBOSE-PHOSPHATE DIPHOSPHOKINASE FAMILY MEMBER RIBOSE-PHOSPHATE DIPHOSPHOKINASE carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;transferase activity#GO:0016740;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;transferase activity, transferring phosphorus-containing groups#GO:0016772;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;anion binding#GO:0043168;ATP binding#GO:0005524 cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;ribose phosphate biosynthetic process#GO:0046390;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695 nucleotide kinase#PC00172;kinase#PC00137 CIOIN|Ensembl=ENSCING00000022559.1|UniProtKB=H2XKN9 H2XKN9 LOC101242405 PTHR23248:SF9 PHOSPHOLIPID SCRAMBLASE-RELATED PHOSPHOLIPID SCRAMBLASE phospholipid transporter activity#GO:0005548;transporter activity#GO:0005215;lipid transporter activity#GO:0005319 organophosphate ester transport#GO:0015748;macromolecule localization#GO:0033036;membrane organization#GO:0061024;plasma membrane organization#GO:0007009;transport#GO:0006810;plasma membrane phospholipid scrambling#GO:0017121;endomembrane system organization#GO:0010256;cellular component organization#GO:0016043;regulation of membrane lipid distribution#GO:0097035;phospholipid transport#GO:0015914;cellular process#GO:0009987;lipid transport#GO:0006869;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;biological regulation#GO:0065007;lipid translocation#GO:0034204;lipid localization#GO:0010876;phospholipid translocation#GO:0045332 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transporter#PC00227 CIOIN|Ensembl=ENSCING00000021696.1|UniProtKB=H2XZ11 H2XZ11 PTHR44329:SF291 SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED PROTEIN KINASE DOMAIN-CONTAINING PROTEIN MAP kinase kinase kinase activity#GO:0004709;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000010516.3|UniProtKB=F6PHR7 F6PHR7 PTHR23195:SF15 YEATS DOMAIN YEATS DOMAIN-CONTAINING PROTEIN 4 protein binding#GO:0005515;histone binding#GO:0042393;binding#GO:0005488 protein-DNA complex organization#GO:0071824;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;cellular component organization#GO:0016043;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;protein-containing complex organization#GO:0043933;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;chromatin remodeling#GO:0006338;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 histone acetyltransferase complex#GO:0000123;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;acetyltransferase complex#GO:1902493;chromatin#GO:0000785;protein-DNA complex#GO:0032993;catalytic complex#GO:1902494;NuA4 histone acetyltransferase complex#GO:0035267;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein acetyltransferase complex#GO:0031248;protein-containing complex#GO:0032991;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227 general transcription factor#PC00259 CIOIN|Ensembl=ENSCING00000019535.1|UniProtKB=H2XRR0 H2XRR0 PTHR24024:SF18 PULMONARY SURFACTANT-ASSOCIATED PROTEIN A SHORT-CHAIN COLLAGEN C4-LIKE extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 surfactant#PC00212;structural protein#PC00211 CIOIN|Ensembl=ENSCING00000014356.2|UniProtKB=F7AZM4 F7AZM4 PTHR21083:SF0 TWISTER DYNEIN AXONEMAL ASSEMBLY FACTOR 6 protein binding#GO:0005515;binding#GO:0005488 cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cell projection organization#GO:0030030;protein-containing complex assembly#GO:0065003;microtubule cytoskeleton organization#GO:0000226;cellular component organization#GO:0016043;axoneme assembly#GO:0035082;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;microtubule bundle formation#GO:0001578;axonemal dynein complex assembly#GO:0070286;cytoskeleton organization#GO:0007010;plasma membrane bounded cell projection assembly#GO:0120031 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000005545.3|UniProtKB=F6XES4 F6XES4 LOC100180798 PTHR10155:SF16 PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT SUPPRESSOR OF CYTOKINE SIGNALING 2 enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207 lipid metabolic process#GO:0006629;phospholipid biosynthetic process#GO:0008654;organophosphate biosynthetic process#GO:0090407;phosphatidylinositol biosynthetic process#GO:0006661;glycerolipid biosynthetic process#GO:0045017;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;phosphatidylinositol metabolic process#GO:0046488;glycerophospholipid metabolic process#GO:0006650;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;phosphatidylinositol phosphate biosynthetic process#GO:0046854;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;glycerophospholipid biosynthetic process#GO:0046474;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;phosphatidylinositol 3-kinase complex#GO:0005942;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;membrane#GO:0016020;transferase complex, transferring phosphorus-containing groups#GO:0061695;extrinsic component of membrane#GO:0019898 kinase modulator#PC00140 CIOIN|Ensembl=ENSCING00000004138.3|UniProtKB=F6UIM4 F6UIM4 LOC100182348 PTHR15141:SF76 TRANSCRIPTION ELONGATION FACTOR B POLYPEPTIDE 3 TRANSCRIPTION ELONGATION FACTOR B POLYPEPTIDE 3 general transcription factor#PC00259 CIOIN|Ensembl=ENSCING00000003626.3|UniProtKB=F6U8U5 F6U8U5 PTHR14205:SF15 WD-REPEAT PROTEIN EARP AND GARP COMPLEX-INTERACTING PROTEIN 1 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;post-translational protein modification#GO:0043687;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;organic substance metabolic process#GO:0071704;primary metabolic process#GO:0044238;metabolic process#GO:0008152 CIOIN|Ensembl=ENSCING00000007900.3|UniProtKB=Q1RL44 Q1RL44 Ci-ZF(C3H)-17 PTHR14493:SF50 UNKEMPT FAMILY MEMBER RING FINGER PROTEIN UNKEMPT CIOIN|Ensembl=ENSCING00000005166.3|UniProtKB=F6RXZ8 F6RXZ8 LOC100180665 PTHR11259:SF2 RAS-RELATED GTP BINDING RAG/GTR YEAST GH16429P GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of catabolic process#GO:0009894;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;response to extracellular stimulus#GO:0009991;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;cellular response to starvation#GO:0009267;positive regulation of TOR signaling#GO:0032008;regulation of signal transduction#GO:0009966;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;negative regulation of cellular process#GO:0048523;cellular response to extracellular stimulus#GO:0031668;regulation of cell communication#GO:0010646;positive regulation of TORC1 signaling#GO:1904263;cellular response to stimulus#GO:0051716;regulation of TORC1 signaling#GO:1903432;regulation of autophagy#GO:0010506;negative regulation of cellular catabolic process#GO:0031330;negative regulation of metabolic process#GO:0009892;cell communication#GO:0007154;response to nutrient levels#GO:0031667;regulation of cellular catabolic process#GO:0031329;negative regulation of autophagy#GO:0010507;cellular process#GO:0009987;regulation of TOR signaling#GO:0032006;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;response to stress#GO:0006950;negative regulation of catabolic process#GO:0009895;regulation of cellular process#GO:0050794;cellular response to nutrient levels#GO:0031669;response to starvation#GO:0042594;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;cellular response to external stimulus#GO:0071496;cellular response to stress#GO:0033554;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;lysosome#GO:0005764;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;lytic vacuole#GO:0000323;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 small GTPase#PC00208;G-protein#PC00020 CIOIN|Ensembl=ENSCING00000007380.3|UniProtKB=F6VBU5 F6VBU5 PTHR11564:SF5 SIGNAL RECOGNITION PARTICLE 54K PROTEIN SRP54 SIGNAL RECOGNITION PARTICLE SUBUNIT SRP54 RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000023810.1|UniProtKB=H2XR08 H2XR08 PTHR22760:SF2 GLYCOSYLTRANSFERASE ALPHA-1,2-MANNOSYLTRANSFERASE ALG9 mannosyltransferase activity#GO:0000030;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein N-linked glycosylation#GO:0006487;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000001528.3|UniProtKB=F6Z448 F6Z448 PTHR24023:SF1095 COLLAGEN ALPHA EGF-LIKE DOMAIN-CONTAINING PROTEIN structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;external encapsulating structure organization#GO:0045229;extracellular matrix organization#GO:0030198 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;extracellular region#GO:0005576 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 Integrin signalling pathway#P00034>Integrin alpha#P00941;Integrin signalling pathway#P00034>Collagen#P00922 CIOIN|Ensembl=ENSCING00000024840.1|UniProtKB=H2XNJ1 H2XNJ1 LOC100186732 PTHR35079:SF1 LUNG ADENOMA SUSCEPTIBILITY PROTEIN 2 LUNG ADENOMA SUSCEPTIBILITY PROTEIN 2 CIOIN|Ensembl=ENSCING00000005839.3|UniProtKB=F6V7V1 F6V7V1 PTHR45737:SF5 VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 5A POLY [ADP-RIBOSE] POLYMERASE-RELATED CIOIN|Ensembl=ENSCING00000017911.1|UniProtKB=H2XPE3 H2XPE3 PTHR12772:SF0 DNA REPLICATION COMPLEX GINS PROTEIN PSF2 DNA REPLICATION COMPLEX GINS PROTEIN PSF2 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;double-strand break repair via homologous recombination#GO:0000724;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;response to stress#GO:0006950;double-strand break repair via break-induced replication#GO:0000727;nitrogen compound metabolic process#GO:0006807;recombinational repair#GO:0000725;cellular response to stress#GO:0033554;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-DNA complex#GO:0032993;DNA replication preinitiation complex#GO:0031261;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular anatomical structure#GO:0005622;GINS complex#GO:0000811;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 DNA metabolism protein#PC00009 CIOIN|Ensembl=ENSCING00000009173.3|UniProtKB=F6Z589 F6Z589 LOC100186298 PTHR15889:SF2 MITOCHONDRIAL RIBOSOMAL PROTEIN L37 LARGE RIBOSOMAL SUBUNIT PROTEIN ML37 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000013569.2|UniProtKB=F6YBG9 F6YBG9 PTHR24246:SF27 OLFACTORY RECEPTOR AND ADENOSINE RECEPTOR ADENOSINE RECEPTOR, ISOFORM A G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711 CIOIN|Ensembl=ENSCING00000021347.1|UniProtKB=H2Y0A6 H2Y0A6 LOC101242365 PTHR13385:SF0 AUTOPHAGY PROTEIN 12 UBIQUITIN-LIKE PROTEIN ATG12 ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;acyltransferase activity#GO:0016746;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824 microautophagy#GO:0016237;cellular component biogenesis#GO:0044085;macroautophagy#GO:0016236;macromolecule modification#GO:0043412;protein modification process#GO:0036211;autophagy of mitochondrion#GO:0000422;biosynthetic process#GO:0009058;post-translational protein modification#GO:0043687;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;cellular component disassembly#GO:0022411;nitrogen compound metabolic process#GO:0006807;catabolic process#GO:0009056;mitochondrion organization#GO:0007005;autophagosome maturation#GO:0097352;protein metabolic process#GO:0019538;protein lipidation#GO:0006497;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular component assembly#GO:0022607;macromolecule biosynthetic process#GO:0009059;protein-containing complex disassembly#GO:0032984;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular component organization#GO:0016043;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organelle disassembly#GO:1903008;lipoprotein biosynthetic process#GO:0042158;primary metabolic process#GO:0044238;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;autophagosome assembly#GO:0000045;lipoprotein metabolic process#GO:0042157;piecemeal microautophagy of the nucleus#GO:0034727;autophagy#GO:0006914 bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;vacuolar membrane#GO:0005774;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;autophagosome#GO:0005776;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;autophagosome membrane#GO:0000421;protein-containing complex#GO:0032991;phagophore assembly site#GO:0000407;membrane-bounded organelle#GO:0043227 CIOIN|Ensembl=ENSCING00000003925.3|UniProtKB=F7AER5 F7AER5 PTHR21373:SF0 GLUCOSE REPRESSIBLE PROTEIN MAK10 N-ALPHA-ACETYLTRANSFERASE 35, NATC AUXILIARY SUBUNIT acetyltransferase#PC00038 CIOIN|Ensembl=ENSCING00000020075.1|UniProtKB=H2XNP6 H2XNP6 LOC100177670 PTHR47979:SF7 DRAB11-RELATED INTRAFLAGELLAR TRANSPORT PROTEIN 27 HOMOLOG GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;anion binding#GO:0043168;ion binding#GO:0043167 cilium organization#GO:0044782;cellular localization#GO:0051641;cell projection organization#GO:0030030;transport#GO:0006810;microtubule-based movement#GO:0007018;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;transport along microtubule#GO:0010970;intraciliary transport#GO:0042073;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;microtubule-based transport#GO:0099111;establishment of localization#GO:0051234;microtubule-based process#GO:0007017;organelle organization#GO:0006996;cytoskeleton-dependent intracellular transport#GO:0030705;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;protein-containing complex localization#GO:0031503 bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intraciliary transport particle B#GO:0030992;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;Golgi membrane#GO:0000139;cilium#GO:0005929;intraciliary transport particle#GO:0030990 small GTPase#PC00208 CIOIN|Ensembl=ENSCING00000004563.3|UniProtKB=F6XDD9 F6XDD9 PTHR12450:SF14 DENTIN MATRIX PROTEIN 4 PROTEIN FAM20 GLYCOSAMINOGLYCAN XYLOSYLKINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;phosphorylation#GO:0016310;protein phosphorylation#GO:0006468;cellular process#GO:0009987;protein metabolic process#GO:0019538;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000008324.4|UniProtKB=F6Q7B5 F6Q7B5 PTHR23052:SF1 AXONEMAL DYNEIN LIGHT CHAIN DOMAIN-CONTAINING PROTEIN 1 AXONEMAL DYNEIN LIGHT CHAIN DOMAIN-CONTAINING PROTEIN 1 CIOIN|Ensembl=ENSCING00000022731.1|UniProtKB=H2XYM5 H2XYM5 LOC100178633 PTHR21439:SF0 OXIDORED-NITRO DOMAIN-CONTAINING PROTEIN PROTEIN OSCP1 localization#GO:0051179;establishment of localization#GO:0051234;transport#GO:0006810 cytoplasm#GO:0005737;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000003966.3|UniProtKB=F6WKA4 F6WKA4 PTHR12027:SF98 WNT RELATED PROTEIN WNT molecular function activator activity#GO:0140677;binding#GO:0005488;molecular function regulator activity#GO:0098772;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;cytokine activity#GO:0005125;G protein-coupled receptor binding#GO:0001664;signaling receptor binding#GO:0005102 cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;neurogenesis#GO:0022008;developmental process#GO:0032502;multicellular organism development#GO:0007275;cell communication#GO:0007154;cell fate commitment#GO:0045165;cell-cell signaling by wnt#GO:0198738;nervous system development#GO:0007399;cellular process#GO:0009987;regulation of biological process#GO:0050789;system development#GO:0048731;response to stimulus#GO:0050896;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;neuron differentiation#GO:0030182;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;cell-cell signaling#GO:0007267;signaling#GO:0023052;canonical Wnt signaling pathway#GO:0060070;Wnt signaling pathway#GO:0016055 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 intercellular signal molecule#PC00207 CIOIN|Ensembl=ENSCING00000022707.1|UniProtKB=H2XXW9 H2XXW9 PTHR19143:SF424 FIBRINOGEN/TENASCIN/ANGIOPOEITIN FIBRINOGEN C-TERMINAL DOMAIN-CONTAINING PROTEIN external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 CIOIN|Ensembl=ENSCING00000018240.1|UniProtKB=H2XWD3 H2XWD3 LOC104266883 PTHR13047:SF0 PRE-MRNA CLEAVAGE FACTOR IM, 25KD SUBUNIT CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 5 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159;mRNA 3'-UTR binding#GO:0003730 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;mRNA processing#GO:0006397;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;mRNA cleavage factor complex#GO:0005849;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA splicing factor#PC00148;RNA processing factor#PC00147;RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000024230.1|UniProtKB=H2Y271 H2Y271 PTHR10127:SF780 DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING METALLOENDOPEPTIDASE hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000003691.3|UniProtKB=F6Y6H6 F6Y6H6 PTHR23351:SF59 FOS TRANSCRIPTION FACTOR-RELATED CYCLIC AMP-DEPENDENT TRANSCRIPTION FACTOR ATF-3-LIKE sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;basic leucine zipper transcription factor#PC00056 CIOIN|Ensembl=ENSCING00000021875.1|UniProtKB=H2XZX8 H2XZX8 LOC100178392 PTHR24390:SF242 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 76 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 CIOIN|Ensembl=ENSCING00000006802.3|UniProtKB=F6UNT7 F6UNT7 PTHR12634:SF8 SIT4 YEAST -ASSOCIATING PROTEIN-RELATED FIERY MOUNTAIN, ISOFORM D phosphatase regulator activity#GO:0019208;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;protein phosphatase regulator activity#GO:0019888 regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;regulation of phosphatase activity#GO:0010921;regulation of dephosphorylation#GO:0035303;regulation of catalytic activity#GO:0050790;regulation of phosphorus metabolic process#GO:0051174;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of molecular function#GO:0065009;biological regulation#GO:0065007;regulation of hydrolase activity#GO:0051336;regulation of phosphoprotein phosphatase activity#GO:0043666;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 phosphatase modulator#PC00184 CIOIN|Ensembl=ENSCING00000004123.3|UniProtKB=F6V9J0 F6V9J0 PTHR10676:SF356 DYNEIN HEAVY CHAIN FAMILY PROTEIN DYNEIN AXONEMAL HEAVY CHAIN 14 cytoskeletal motor activity#GO:0003774;microtubule motor activity#GO:0003777;protein binding#GO:0005515;ATP-dependent activity#GO:0140657;binding#GO:0005488 cilium-dependent cell motility#GO:0060285;microtubule-based process#GO:0007017;cilium or flagellum-dependent cell motility#GO:0001539;microtubule-based movement#GO:0007018;cell motility#GO:0048870;cellular process#GO:0009987;cilium movement involved in cell motility#GO:0060294;cilium movement#GO:0003341 catalytic complex#GO:1902494;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule associated complex#GO:0005875;motile cilium#GO:0031514;protein-containing complex#GO:0032991;9+2 motile cilium#GO:0097729;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;dynein complex#GO:0030286;cytoskeleton#GO:0005856;cell projection#GO:0042995;cilium#GO:0005929 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 CIOIN|Ensembl=ENSCING00000021568.1|UniProtKB=H2Y0A0 H2Y0A0 PTHR10003:SF98 SUPEROXIDE DISMUTASE CU-ZN -RELATED SUPEROXIDE DISMUTASE [CU-ZN] cation binding#GO:0043169;antioxidant activity#GO:0016209;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;transition metal ion binding#GO:0046914;copper ion binding#GO:0005507;metal ion binding#GO:0046872;ion binding#GO:0043167;oxidoreductase activity#GO:0016491 cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;cellular metabolic process#GO:0044237;response to oxidative stress#GO:0006979;cellular process#GO:0009987;response to stimulus#GO:0050896;cellular response to oxygen-containing compound#GO:1901701;detoxification#GO:0098754;response to stress#GO:0006950;response to chemical#GO:0042221;cellular response to oxidative stress#GO:0034599;response to toxic substance#GO:0009636;response to reactive oxygen species#GO:0000302;cellular response to stress#GO:0033554;metabolic process#GO:0008152 oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000005437.3|UniProtKB=F6UUY2 F6UUY2 PTHR10010:SF46 SOLUTE CARRIER FAMILY 34 SODIUM PHOSPHATE , MEMBER 2-RELATED SODIUM-DEPENDENT PHOSPHATE TRANSPORT PROTEIN 2B secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000004969.3|UniProtKB=H2XYZ3 H2XYZ3 PTHR11731:SF202 PROTEASE FAMILY S9B,C DIPEPTIDYL-PEPTIDASE IV-RELATED DIPEPTIDYL PEPTIDASE FAMILY MEMBER 2 hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 serine protease#PC00203;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000021647.1|UniProtKB=H2XM68 H2XM68 PTHR11929:SF145 ALPHA- 1,3 -FUCOSYLTRANSFERASE ALPHA-(1,3)-FUCOSYLTRANSFERASE FUT-1 transferase activity#GO:0016740;fucosyltransferase activity#GO:0008417;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 glycosylation#GO:0070085;metabolic process#GO:0008152 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000022568.1|UniProtKB=H2XM10 H2XM10 LOC100180473 PTHR46857:SF2 EPITHELIAL CELL-TRANSFORMING SEQUENCE 2 ONCOGENE-LIKE F-BOX ONLY PROTEIN 16 CIOIN|Ensembl=ENSCING00000004356.3|UniProtKB=F7B4R7 F7B4R7 LOC100178045 PTHR44147:SF2 DEHYDROGENASE/REDUCTASE SDR FAMILY MEMBER 1 DEHYDROGENASE_REDUCTASE SDR FAMILY MEMBER 1 dehydrogenase#PC00092;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000008963.3|UniProtKB=F6Q5K0 F6Q5K0 PTHR18914:SF9 ALPHA CATENIN CATENIN ALPHA cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;beta-catenin binding#GO:0008013;actin filament binding#GO:0051015 cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cell motility#GO:0048870;cellular process#GO:0009987;cell migration#GO:0016477 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;adherens junction#GO:0005912;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;extrinsic component of membrane#GO:0019898 non-motor actin binding protein#PC00165 Alzheimer disease-presenilin pathway#P00004>alpha-catenin#P00133;Wnt signaling pathway#P00057>alpha-catenin#P01471 CIOIN|Ensembl=ENSCING00000021042.1|UniProtKB=H2XSG1 H2XSG1 PTHR19325:SF574 COMPLEMENT COMPONENT-RELATED SUSHI DOMAIN-CONTAINING SUSHI, VON WILLEBRAND FACTOR TYPE A, EGF AND PENTRAXIN DOMAIN-CONTAINING PROTEIN 1 complement component#PC00078 CIOIN|Ensembl=ENSCING00000013291.2|UniProtKB=F7BLC0 F7BLC0 PTHR11388:SF157 ORGANIC ANION TRANSPORTER SOLUTE CARRIER ORGANIC ANION TRANSPORTER FAMILY MEMBER 2A1-LIKE secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 localization#GO:0051179;organic substance transport#GO:0071702;establishment of localization#GO:0051234;organic anion transport#GO:0015711;transport#GO:0006810 basal plasma membrane#GO:0009925;basolateral plasma membrane#GO:0016323;plasma membrane region#GO:0098590;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;basal part of cell#GO:0045178;plasma membrane#GO:0005886 transporter#PC00227 CIOIN|Ensembl=ENSCING00000000422.3|UniProtKB=F7BL24 F7BL24 PTHR24372:SF77 GLYCOPROTEIN HORMONE RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 response to organic substance#GO:0010033;positive regulation of adenylate cyclase activity#GO:0045762;regulation of lyase activity#GO:0051339;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;cellular response to stimulus#GO:0051716;regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;cellular response to endogenous stimulus#GO:0071495;cellular response to chemical stimulus#GO:0070887;positive regulation of catalytic activity#GO:0043085;cellular response to organic substance#GO:0071310;regulation of cyclase activity#GO:0031279;positive regulation of molecular function#GO:0044093;cell communication#GO:0007154;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;positive regulation of cyclase activity#GO:0031281;hormone-mediated signaling pathway#GO:0009755;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to endogenous stimulus#GO:0009719;response to hormone#GO:0009725;cellular response to hormone stimulus#GO:0032870;response to chemical#GO:0042221;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of lyase activity#GO:0051349;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 CIOIN|Ensembl=ENSCING00000019967.1|UniProtKB=H2XN94 H2XN94 PTHR16165:SF5 NXPE FAMILY MEMBER NXPE FAMILY MEMBER 3 CIOIN|Ensembl=ENSCING00000018643.1|UniProtKB=F6SY07 F6SY07 PTHR16165:SF5 NXPE FAMILY MEMBER NXPE FAMILY MEMBER 3 CIOIN|Ensembl=ENSCING00000017896.1|UniProtKB=H2XV24 H2XV24 PTHR15895:SF13 IMMEDIATE EARLY RESPONSE GENE IMMEDIATE EARLY RESPONSE GENE 5-LIKE PROTEIN CIOIN|Ensembl=ENSCING00000022759.1|UniProtKB=H2XVX3 H2XVX3 PTHR10579:SF172 CALCIUM-ACTIVATED CHLORIDE CHANNEL REGULATOR CALCIUM-ACTIVATED CHLORIDE CHANNEL REGULATOR 4 PRECURSOR-RELATED ion channel#PC00133;transporter#PC00227 CIOIN|Ensembl=ENSCING00000003377.4|UniProtKB=F7A713 F7A713 PTHR43261:SF1 TRANSLATION ELONGATION FACTOR G-RELATED RIBOSOME-RELEASING FACTOR 2, MITOCHONDRIAL cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;cellular component disassembly#GO:0022411;cellular process#GO:0009987;organelle disassembly#GO:1903008;organelle organization#GO:0006996 translation elongation factor#PC00222;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000006120.3|UniProtKB=F6VS92 F6VS92 PTHR11819:SF150 SOLUTE CARRIER FAMILY 5 SODIUM_MYO-INOSITOL COTRANSPORTER inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;carbohydrate transmembrane transporter activity#GO:0015144;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;sugar transmembrane transporter activity#GO:0051119;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;active transmembrane transporter activity#GO:0022804;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;active monoatomic ion transmembrane transporter activity#GO:0022853;monoatomic ion transmembrane transporter activity#GO:0015075;inorganic cation transmembrane transporter activity#GO:0022890;solute:monoatomic cation symporter activity#GO:0015294 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000008955.3|UniProtKB=F6Q5Y8 F6Q5Y8 PTHR24223:SF447 ATP-BINDING CASSETTE SUB-FAMILY C MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN 5 transmembrane transporter activity#GO:0022857;primary active transmembrane transporter activity#GO:0015399;ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 localization#GO:0051179;establishment of localization#GO:0051234;cellular process#GO:0009987;transmembrane transport#GO:0055085;transport#GO:0006810 cellular anatomical entity#GO:0110165;membrane#GO:0016020 ATP-binding cassette (ABC) transporter#PC00003;transporter#PC00227 CIOIN|Ensembl=ENSCING00000011451.2|UniProtKB=F6ZUW9 F6ZUW9 PTHR13398:SF0 GDP-FUCOSE PROTEIN O-FUCOSYLTRANSFERASE 2 GDP-FUCOSE PROTEIN O-FUCOSYLTRANSFERASE 2 transferase activity#GO:0016740;fucosyltransferase activity#GO:0008417;catalytic activity, acting on a protein#GO:0140096;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000023410.1|UniProtKB=H2Y1G0 H2Y1G0 LOC100179361 PTHR45833:SF1 METHIONINE SYNTHASE METHIONINE SYNTHASE methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;sulfur compound metabolic process#GO:0006790;proteinogenic amino acid biosynthetic process#GO:0170038;folic acid-containing compound metabolic process#GO:0006760;biosynthetic process#GO:0009058;carboxylic acid biosynthetic process#GO:0046394;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular modified amino acid metabolic process#GO:0006575;amino acid biosynthetic process#GO:0008652;alpha-amino acid metabolic process#GO:1901605;L-amino acid metabolic process#GO:0170033;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;proteinogenic amino acid metabolic process#GO:0170039;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;aspartate family amino acid biosynthetic process#GO:0009067;alpha-amino acid biosynthetic process#GO:1901607;aspartate family amino acid metabolic process#GO:0009066;L-amino acid biosynthetic process#GO:0170034;small molecule biosynthetic process#GO:0044283;carboxylic acid metabolic process#GO:0019752;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 S-adenosylmethionine biosynthesis#P02773>Cobalamin-dependent homocysteine transmethylase#P03142;Methionine biosynthesis#P02753>Homocysteine transmethylase#P03024;Formyltetrahydrofolate biosynthesis#P02743>Cobalamin dependent homocysteine transmethylase#P02953 CIOIN|Ensembl=ENSCING00000011695.2|UniProtKB=F7BAS4 F7BAS4 PTHR12011:SF471 ADHESION G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 2 PROFILE 2 DOMAIN-CONTAINING PROTEIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 CIOIN|Ensembl=ENSCING00000007393.3|UniProtKB=F6ULA0 F6ULA0 LOC100179415 PTHR20765:SF1 SOLUTE CARRIER FAMILY 43 MEMBER 3-RELATED EQUILIBRATIVE NUCLEOBASE TRANSPORTER 1 amino acid transporter#PC00046;secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000001704.3|UniProtKB=F6UJB5 F6UJB5 PTHR13462:SF10 CALCIUM UNIPORTER PROTEIN, MITOCHONDRIAL CALCIUM UNIPORTER PROTEIN, MITOCHONDRIAL calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation channel activity#GO:0005261;secondary active transmembrane transporter activity#GO:0015291;inorganic molecular entity transmembrane transporter activity#GO:0015318;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;metal ion transmembrane transporter activity#GO:0046873;monoatomic cation transmembrane transporter activity#GO:0008324;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267;inorganic cation transmembrane transporter activity#GO:0022890 inorganic ion homeostasis#GO:0098771;metal ion transport#GO:0030001;calcium ion homeostasis#GO:0055074;transmembrane transport#GO:0055085;calcium ion transmembrane transport#GO:0070588;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;homeostatic process#GO:0042592;inorganic ion transmembrane transport#GO:0098660;chemical homeostasis#GO:0048878;cellular process#GO:0009987;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;calcium ion transport#GO:0006816;intracellular calcium ion homeostasis#GO:0006874;monoatomic ion homeostasis#GO:0050801;localization#GO:0051179;mitochondrial transport#GO:0006839;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation transport#GO:0006812;mitochondrial calcium ion homeostasis#GO:0051560;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion transport#GO:0006811;mitochondrial transmembrane transport#GO:1990542;monoatomic cation transmembrane transport#GO:0098655 envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;transporter complex#GO:1990351;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;calcium channel complex#GO:0034704;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cation channel complex#GO:0034703;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;mitochondrial envelope#GO:0005740;transmembrane transporter complex#GO:1902495;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227;mitochondrial protein-containing complex#GO:0098798 CIOIN|Ensembl=ENSCING00000004131.3|UniProtKB=F6ZNA8 F6ZNA8 LOC100186458 PTHR11042:SF185 EUKARYOTIC TRANSLATION INITIATION FACTOR 2-ALPHA KINASE EIF2-ALPHA KINASE -RELATED WEE1-LIKE PROTEIN KINASE protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;phosphorylation#GO:0016310;protein phosphorylation#GO:0006468;cellular process#GO:0009987;protein metabolic process#GO:0019538;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000013663.2|UniProtKB=F6TNN9 F6TNN9 PTHR48026:SF14 HOMOLOGOUS TO DROSOPHILA SQD (SQUID) PROTEIN HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN A1 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159;mRNA 3'-UTR binding#GO:0003730 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;mRNA splicing, via spliceosome#GO:0000398;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 ribonucleoprotein complex#GO:1990904;catalytic step 2 spliceosome#GO:0071013;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA processing factor#PC00147;RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000007252.3|UniProtKB=F6UVN7 F6UVN7 PTHR12703:SF4 TRANSMEMBRANE PROTEIN 33 TRANSMEMBRANE PROTEIN 33 cellular component organization or biogenesis#GO:0071840;endoplasmic reticulum organization#GO:0007029;endoplasmic reticulum tubular network organization#GO:0071786;membrane organization#GO:0061024;organelle organization#GO:0006996;endomembrane system organization#GO:0010256;cellular component organization#GO:0016043;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000021483.1|UniProtKB=H2XPV5 H2XPV5 PTHR12192:SF2 CATION TRANSPORT PROTEIN CHAC-RELATED GLUTATHIONE-SPECIFIC GAMMA-GLUTAMYLCYCLOTRANSFERASE 2 lyase activity#GO:0016829;catalytic activity#GO:0003824 sulfur compound metabolic process#GO:0006790;peptide metabolic process#GO:0006518;organonitrogen compound metabolic process#GO:1901564;peptide catabolic process#GO:0043171;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;glutathione metabolic process#GO:0006749;sulfur compound catabolic process#GO:0044273;nitrogen compound metabolic process#GO:0006807;cellular modified amino acid metabolic process#GO:0006575;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000021624.1|UniProtKB=H2XKA9 H2XKA9 LOC100178802 PTHR11125:SF7 SUPPRESSOR OF TY 5 TRANSCRIPTION ELONGATION FACTOR SPT5 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;DNA-templated transcription#GO:0006351;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;DNA-templated transcription elongation#GO:0006354;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;RNA biosynthetic process#GO:0032774;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nucleobase-containing compound biosynthetic process#GO:0034654;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;aromatic compound biosynthetic process#GO:0019438;transcription elongation by RNA polymerase II#GO:0006368;transcription by RNA polymerase II#GO:0006366;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;transcription elongation factor complex#GO:0008023;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000022138.1|UniProtKB=H2XY54 H2XY54 PTHR33962:SF1 RECQ-MEDIATED GENOME INSTABILITY PROTEIN 2 RMI2 RECQ-MEDIATED GENOME INSTABILITY PROTEIN 2 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;regulation of double-strand break repair#GO:2000779;negative regulation of biological process#GO:0048519;regulation of chromosome segregation#GO:0051983;regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA metabolic process#GO:0051052;negative regulation of DNA repair#GO:0045738;regulation of cellular component organization#GO:0051128;regulation of DNA repair#GO:0006282;nucleobase-containing compound metabolic process#GO:0006139;regulation of double-strand break repair via homologous recombination#GO:0010569;regulation of biological process#GO:0050789;DNA damage response#GO:0006974;regulation of cellular response to stress#GO:0080135;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;negative regulation of DNA recombination#GO:0045910;negative regulation of DNA metabolic process#GO:0051053;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of chromosome organization#GO:0033044;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;negative regulation of response to stimulus#GO:0048585;macromolecule metabolic process#GO:0043170;regulation of organelle organization#GO:0033043;regulation of response to stress#GO:0080134;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;regulation of cell cycle process#GO:0010564;regulation of primary metabolic process#GO:0080090;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;negative regulation of double-strand break repair#GO:2000780;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of sister chromatid segregation#GO:0033045;negative regulation of double-strand break repair via homologous recombination#GO:2000042;regulation of DNA recombination#GO:0000018;cellular response to stress#GO:0033554;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;DNA metabolic process#GO:0006259 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;nuclear speck#GO:0016607;organelle#GO:0043226;nuclear body#GO:0016604;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 CIOIN|Ensembl=ENSCING00000022886.1|UniProtKB=H2XLF7 H2XLF7 PTHR24044:SF506 NOTCH LIGAND FAMILY MEMBER NEUROGENIC LOCUS NOTCH HOMOLOG PROTEIN 2-LIKE protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 intercellular signal molecule#PC00207 CIOIN|Ensembl=ENSCING00000020105.1|UniProtKB=H2XRF1 H2XRF1 PTHR33444:SF2 SI:DKEY-19B23.12-RELATED MARVEL DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000003245.3|UniProtKB=F6ZNK2 F6ZNK2 LOC100182374 PTHR12400:SF21 INOSITOL POLYPHOSPHATE KINASE KINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301 organic hydroxy compound metabolic process#GO:1901615;organophosphate biosynthetic process#GO:0090407;alcohol biosynthetic process#GO:0046165;cellular metabolic process#GO:0044237;alcohol metabolic process#GO:0006066;organic hydroxy compound biosynthetic process#GO:1901617;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;organophosphate metabolic process#GO:0019637;small molecule biosynthetic process#GO:0044283;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 kinase#PC00137 CIOIN|Ensembl=ENSCING00000007608.3|UniProtKB=F6ZJN0 F6ZJN0 PTHR15034:SF5 DEATH DOMAIN-CONTAINING PROTEIN CRADD DEATH DOMAIN-CONTAINING PROTEIN CRADD Wnt signaling pathway#P00057>Frizzled#P01428;Apoptosis signaling pathway#P00006>RAIDD#P00294;Cadherin signaling pathway#P00012>Frizzled#P00475;Alzheimer disease-presenilin pathway#P00004>Frizzled#P00119 CIOIN|Ensembl=ENSCING00000002537.3|UniProtKB=F6X2V0 F6X2V0 LOC100176679 PTHR13587:SF7 INTEGRATOR COMPLEX SUBUNIT 3 INTEGRATOR COMPLEX SUBUNIT 3 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000012228.2|UniProtKB=F7B5Z4 F7B5Z4 LOC100184455 PTHR11716:SF106 PHOSPHOLIPASE A2 FAMILY MEMBER PHOSPHOLIPASE A2 A2-ACTITOXIN-UCS2A-LIKE cation binding#GO:0043169;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;phospholipase A2 activity#GO:0004623;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;lipid binding#GO:0008289;phospholipase activity#GO:0004620;ion binding#GO:0043167;phospholipid binding#GO:0005543 lipid metabolic process#GO:0006629;cellular metabolic process#GO:0044237;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;phospholipid metabolic process#GO:0006644;cellular lipid metabolic process#GO:0044255;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 phospholipase#PC00186 CIOIN|Ensembl=ENSCING00000005198.3|UniProtKB=F7B6Y6 F7B6Y6 LOC100183298 PTHR35665:SF1 PROTEIN LKAAEAR1 PROTEIN LKAAEAR1 CIOIN|Ensembl=ENSCING00000008351.3|UniProtKB=F7B3N6 F7B3N6 LOC100178265 PTHR43969:SF9 GLUTATHIONE S TRANSFERASE D10, ISOFORM A-RELATED GLUTATHIONE S TRANSFERASE D10, ISOFORM A-RELATED glutathione transferase activity#GO:0004364;transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824 sulfur compound metabolic process#GO:0006790;nitrogen compound metabolic process#GO:0006807;peptide metabolic process#GO:0006518;cellular modified amino acid metabolic process#GO:0006575;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular process#GO:0009987;glutathione metabolic process#GO:0006749;amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000006022.3|UniProtKB=F6SFP2 F6SFP2 LOC100184385 PTHR24343:SF299 SERINE/THREONINE KINASE SERINE_THREONINE-PROTEIN KINASE KIN-29 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;nitrogen compound metabolic process#GO:0006807;biological regulation#GO:0065007;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000017951.1|UniProtKB=H2XTG6 H2XTG6 PTHR10869:SF244 PROLYL 4-HYDROXYLASE ALPHA SUBUNIT PROLYL 4-HYDROXYLASE SUBUNIT ALPHA-2 2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;dioxygenase activity#GO:0051213 oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular modified amino acid metabolic process#GO:0006575;protein hydroxylation#GO:0018126;alpha-amino acid metabolic process#GO:1901605;protein metabolic process#GO:0019538;carboxylic acid metabolic process#GO:0019752;L-amino acid metabolic process#GO:0170033;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000007995.3|UniProtKB=F6W453 F6W453 PTHR45885:SF1 CELL DIVISION CYCLE 5-LIKE PROTEIN CELL DIVISION CYCLE 5-LIKE PROTEIN cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;Prp19 complex#GO:0000974;spliceosomal complex#GO:0005681;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000014848.2|UniProtKB=H2XRC6 H2XRC6 PTHR24030:SF0 PROTEIN CMSS1 PROTEIN CMSS1 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;90S preribosome#GO:0030686;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000000170.3|UniProtKB=F6SY47 F6SY47 vkor PTHR14519:SF5 VITAMIN K EPOXIDE REDUCTASE COMPLEX, SUBUNIT 1 VITAMIN K EPOXIDE REDUCTASE COMPLEX SUBUNIT 1-LIKE PROTEIN 1 catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular process#GO:0009987;protein metabolic process#GO:0019538;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000007532.3|UniProtKB=F6TVM0 F6TVM0 LOC100177439 PTHR46588:SF1 SERINE/THREONINE/TYROSINE-INTERACTING PROTEIN SERINE_THREONINE_TYROSINE-INTERACTING PROTEIN protein binding#GO:0005515;binding#GO:0005488 negative regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032435;regulation of MAPK cascade#GO:0043408;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;regulation of catabolic process#GO:0009894;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of protein catabolic process#GO:0042177;regulation of signaling#GO:0023051;regulation of protein catabolic process#GO:0042176;regulation of proteolysis involved in protein catabolic process#GO:1903050;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;negative regulation of proteasomal protein catabolic process#GO:1901799;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;regulation of cell communication#GO:0010646;regulation of proteolysis#GO:0030162;negative regulation of metabolic process#GO:0009892;negative regulation of proteolysis#GO:0045861;negative regulation of protein metabolic process#GO:0051248;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of primary metabolic process#GO:0080090;regulation of proteasomal protein catabolic process#GO:0061136;regulation of response to stimulus#GO:0048583;negative regulation of catabolic process#GO:0009895;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of ERK1 and ERK2 cascade#GO:0070372;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of proteolysis involved in protein catabolic process#GO:1903051;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434;regulation of metabolic process#GO:0019222;negative regulation of molecular function#GO:0044092 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 Oxidative stress response#P00046>MKP5#P01131 CIOIN|Ensembl=ENSCING00000022831.1|UniProtKB=H2XT45 H2XT45 LOC113475776 PTHR48012:SF18 STERILE20-LIKE KINASE, ISOFORM B-RELATED HAPPYHOUR, ISOFORM A transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;nitrogen compound metabolic process#GO:0006807;biological regulation#GO:0065007;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Apoptosis signaling pathway#P00006>GCKR#P00311;Apoptosis signaling pathway#P00006>GCK#P00268 CIOIN|Ensembl=ENSCING00000003112.3|UniProtKB=F6PHL6 F6PHL6 tbx6b PTHR11267:SF204 T-BOX PROTEIN-RELATED SPADETAIL sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cell fate commitment#GO:0045165;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;cell fate specification#GO:0001708;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;Rel homology transcription factor#PC00252;immunoglobulin fold transcription factor#PC00251 CIOIN|Ensembl=ENSCING00000007269.3|UniProtKB=F6THU3 F6THU3 PTHR24300:SF397 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 2U1 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;tetrapyrrole binding#GO:0046906;steroid hydroxylase activity#GO:0008395;oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497;heme binding#GO:0020037 response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;response to chemical#GO:0042221;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 oxygenase#PC00177;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000022792.1|UniProtKB=H2XZS4 H2XZS4 PTHR11388:SF100 ORGANIC ANION TRANSPORTER SOLUTE CARRIER ORGANIC ANION TRANSPORTER FAMILY MEMBER 4A1 transporter#PC00227 CIOIN|Ensembl=ENSCING00000007313.3|UniProtKB=F6XZ93 F6XZ93 LOC100177203 PTHR11902:SF1 ENOLASE ENOLASE lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835;hydro-lyase activity#GO:0016836;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;ribonucleoside triphosphate metabolic process#GO:0009199;nucleoside triphosphate metabolic process#GO:0009141;carbohydrate derivative metabolic process#GO:1901135;heterocycle catabolic process#GO:0046700;organonitrogen compound catabolic process#GO:1901565;ribonucleotide catabolic process#GO:0009261;pyridine nucleotide metabolic process#GO:0019362;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;cellular nitrogen compound catabolic process#GO:0044270;purine-containing compound catabolic process#GO:0072523;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;purine nucleotide catabolic process#GO:0006195;ATP metabolic process#GO:0046034;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;purine ribonucleotide catabolic process#GO:0009154;nucleoside phosphate metabolic process#GO:0006753;carbohydrate catabolic process#GO:0016052;purine-containing compound metabolic process#GO:0072521;pyridine-containing compound metabolic process#GO:0072524;catabolic process#GO:0009056;nucleoside diphosphate metabolic process#GO:0009132;organic substance catabolic process#GO:1901575;carbohydrate metabolic process#GO:0005975;purine nucleotide metabolic process#GO:0006163;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;oxoacid metabolic process#GO:0043436;nucleoside phosphate catabolic process#GO:1901292;carbohydrate derivative catabolic process#GO:1901136;purine ribonucleoside triphosphate metabolic process#GO:0009205;generation of precursor metabolites and energy#GO:0006091;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;nucleotide catabolic process#GO:0009166;cellular nitrogen compound metabolic process#GO:0034641;nicotinamide nucleotide metabolic process#GO:0046496;cellular process#GO:0009987;nucleoside diphosphate catabolic process#GO:0009134;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;organophosphate catabolic process#GO:0046434;aromatic compound catabolic process#GO:0019439;glycolytic process#GO:0006096;organic cyclic compound catabolic process#GO:1901361;organophosphate metabolic process#GO:0019637;purine nucleoside triphosphate metabolic process#GO:0009144;nucleobase-containing compound catabolic process#GO:0034655;nucleotide metabolic process#GO:0009117;carboxylic acid metabolic process#GO:0019752;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622 lyase#PC00144 Glycolysis#P00024>Enolase#P00678 CIOIN|Ensembl=ENSCING00000016236.2|UniProtKB=F6Z897 F6Z897 LOC100183305 PTHR11449:SF1 RIBOSOMAL PROTEIN L30 LARGE RIBOSOMAL SUBUNIT PROTEIN EL30 ribosomal protein#PC00202;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000005667.3|UniProtKB=F6YY92 F6YY92 PTHR22298:SF29 ENDO-1,4-BETA-GLUCANASE ENDOGLUCANASE CIOIN|Ensembl=ENSCING00000015173.2|UniProtKB=F6XYG2 F6XYG2 LOC100185261 PTHR13344:SF0 NADH-UBIQUINONE OXIDOREDUCTASE NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 8 envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;respiratory chain complex#GO:0098803;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transporter complex#GO:1990351;oxidoreductase complex#GO:1990204;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;respirasome#GO:0070469;mitochondrial respiratory chain complex I#GO:0005747;protein-containing complex#GO:0032991;mitochondrial envelope#GO:0005740;inner mitochondrial membrane protein complex#GO:0098800;transmembrane transporter complex#GO:1902495;mitochondrial respirasome#GO:0005746;membrane-bounded organelle#GO:0043227;respiratory chain complex I#GO:0045271;NADH dehydrogenase complex#GO:0030964;mitochondrial protein-containing complex#GO:0098798 oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000013271.2|UniProtKB=F7BMD5 F7BMD5 LOC100180085 PTHR15924:SF9 CLE RNA TRANSCRIPTION, TRANSLATION AND TRANSPORT FACTOR PROTEIN nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;tRNA splicing, via endonucleolytic cleavage and ligation#GO:0006388;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;catalytic complex#GO:1902494 CIOIN|Ensembl=ENSCING00000004741.3|UniProtKB=F6PMK8 F6PMK8 PTHR11566:SF21 DYNAMIN DYNAMIN RELATED PROTEIN 1, ISOFORM A GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;microtubule binding#GO:0008017;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;ribonucleoside triphosphate phosphatase activity#GO:0017111 supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;organelle#GO:0043226;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150 CIOIN|Ensembl=ENSCING00000007678.3|UniProtKB=F6T636 F6T636 LOC100183306 PTHR10751:SF29 GUANYLATE BINDING PROTEIN ATLASTIN GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;ion binding#GO:0043167;anion binding#GO:0043168 heterotrimeric G-protein#PC00117;G-protein#PC00020 CIOIN|Ensembl=ENSCING00000009763.3|UniProtKB=Q68A31 Q68A31 Ci-PSL3 PTHR12174:SF23 SIGNAL PEPTIDE PEPTIDASE MINOR HISTOCOMPATIBILITY ANTIGEN H13 hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;aspartic-type endopeptidase activity#GO:0004190;catalytic activity#GO:0003824 macromolecule biosynthetic process#GO:0009059;membrane protein proteolysis#GO:0033619;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;protein processing#GO:0016485;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;signal peptide processing#GO:0006465;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;side of membrane#GO:0098552;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 aspartic protease#PC00053;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000001142.3|UniProtKB=F6YV26 F6YV26 PTHR11929:SF145 ALPHA- 1,3 -FUCOSYLTRANSFERASE ALPHA-(1,3)-FUCOSYLTRANSFERASE FUT-1 transferase activity#GO:0016740;fucosyltransferase activity#GO:0008417;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 glycosylation#GO:0070085;metabolic process#GO:0008152 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000022230.1|UniProtKB=A0A1W2W5D3 A0A1W2W5D3 LOC100181237 PTHR12461:SF99 HYPOXIA-INDUCIBLE FACTOR 1 ALPHA INHIBITOR-RELATED BIFUNCTIONAL PEPTIDASE AND (3S)-LYSYL HYDROXYLASE JMJD7 protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000008821.3|UniProtKB=F7BJ17 F7BJ17 PTHR10272:SF0 PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE carboxylic ester hydrolase activity#GO:0052689;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000013622.2|UniProtKB=F6V0W8 F6V0W8 PTHR10660:SF2 PROTEASOME REGULATOR PA28 LD45860P peptidase activator activity#GO:0016504;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;peptidase regulator activity#GO:0061134;endopeptidase regulator activity#GO:0061135;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of protein metabolic process#GO:0051246;regulation of catabolic process#GO:0009894;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of molecular function#GO:0044093;regulation of protein catabolic process#GO:0042176;regulation of proteolysis involved in protein catabolic process#GO:1903050;regulation of catalytic activity#GO:0050790;positive regulation of proteolysis#GO:0045862;regulation of biological process#GO:0050789;positive regulation of metabolic process#GO:0009893;regulation of molecular function#GO:0065009;regulation of hydrolase activity#GO:0051336;regulation of G1/S transition of mitotic cell cycle#GO:2000045;positive regulation of peptidase activity#GO:0010952;positive regulation of biological process#GO:0048518;regulation of proteolysis#GO:0030162;regulation of mitotic cell cycle phase transition#GO:1901990;positive regulation of catalytic activity#GO:0043085;regulation of cell cycle phase transition#GO:1901987;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of hydrolase activity#GO:0051345;regulation of cell cycle process#GO:0010564;regulation of primary metabolic process#GO:0080090;regulation of proteasomal protein catabolic process#GO:0061136;positive regulation of protein metabolic process#GO:0051247;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;regulation of endopeptidase activity#GO:0052548;regulation of peptidase activity#GO:0052547;regulation of mitotic cell cycle#GO:0007346;positive regulation of endopeptidase activity#GO:0010950;regulation of cell cycle G1/S phase transition#GO:1902806;regulation of metabolic process#GO:0019222 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000004738.3|UniProtKB=F6PS87 F6PS87 PTHR10044:SF139 INHIBITOR OF APOPTOSIS DEATH-ASSOCIATED INHIBITOR OF APOPTOSIS 2 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protease inhibitor#PC00191 CIOIN|Ensembl=ENSCING00000009493.3|UniProtKB=F7ADG5 F7ADG5 PTHR11358:SF26 ARGINASE/AGMATINASE GUANIDINO ACID HYDROLASE, MITOCHONDRIAL hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;catalytic activity#GO:0003824 amine metabolic process#GO:0009308;oxoacid metabolic process#GO:0043436;biogenic amine metabolic process#GO:0006576;arginine metabolic process#GO:0006525;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;polyamine metabolic process#GO:0006595;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;alpha-amino acid metabolic process#GO:1901605;polyamine biosynthetic process#GO:0006596;carboxylic acid metabolic process#GO:0019752;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000003343.3|UniProtKB=F6S1R1 F6S1R1 PTHR20905:SF1 N-ACETYLTRANSFERASE-RELATED AT07410P-RELATED acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;N-acetyltransferase activity#GO:0008080;acyltransferase activity#GO:0016746;acetyltransferase activity#GO:0016407;catalytic activity#GO:0003824;N-acyltransferase activity#GO:0016410 acetyltransferase#PC00038 CIOIN|Ensembl=ENSCING00000001798.3|UniProtKB=F6X5R6 F6X5R6 PTHR13976:SF76 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN-RELATED AT27789P ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 RNA splicing factor#PC00148;RNA metabolism protein#PC00031;RNA processing factor#PC00147 CIOIN|Ensembl=ENSCING00000006881.3|UniProtKB=F6YV51 F6YV51 PTHR13931:SF16 UBIQUITINATION FACTOR E4 UBIQUITIN CONJUGATION FACTOR E4 A transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 macromolecule modification#GO:0043412;protein catabolic process#GO:0030163;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;post-translational protein modification#GO:0043687;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;protein polyubiquitination#GO:0000209;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;protein ubiquitination#GO:0016567;macromolecule catabolic process#GO:0009057;response to endoplasmic reticulum stress#GO:0034976;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;ERAD pathway#GO:0036503;response to organonitrogen compound#GO:0010243;cellular process#GO:0009987;primary metabolic process#GO:0044238;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;cellular response to stress#GO:0033554 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000012591.2|UniProtKB=F6Y3T4 F6Y3T4 PTHR19957:SF411 SYNTAXIN LD23667P molecular adaptor activity#GO:0060090;protein binding#GO:0005515;SNAP receptor activity#GO:0005484;binding#GO:0005488;SNARE binding#GO:0000149;protein-macromolecule adaptor activity#GO:0030674 vesicle fusion#GO:0006906;cellular localization#GO:0051641;organelle localization#GO:0051640;macromolecule localization#GO:0033036;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;membrane fusion#GO:0061025;establishment of localization#GO:0051234;organelle organization#GO:0006996;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;vesicle organization#GO:0016050;intracellular transport#GO:0046907;organelle fusion#GO:0048284 presynapse#GO:0098793;membrane protein complex#GO:0098796;synapse#GO:0045202;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;synaptic vesicle#GO:0008021;SNARE complex#GO:0031201;cell junction#GO:0030054;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;transport vesicle#GO:0030133;secretory vesicle#GO:0099503 SNARE protein#PC00034;membrane traffic protein#PC00150 Adrenaline and noradrenaline biosynthesis#P00001>SNARE#P00072;Parkinson disease#P00049>Syntaxin#P01215 CIOIN|Ensembl=ENSCING00000018620.1|UniProtKB=H2XQH7 H2XQH7 PTHR48034:SF21 TRANSFORMER-2 SEX-DETERMINING PROTEIN-RELATED TRANSFORMER-2 PROTEIN HOMOLOG BETA-LIKE ISOFORM X1 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 positive regulation of gene expression#GO:0010628;positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of mRNA metabolic process#GO:1903313;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;biological regulation#GO:0065007;regulation of mRNA processing#GO:0050684;regulation of gene expression#GO:0010468;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule biosynthetic process#GO:0010556;regulation of mRNA splicing, via spliceosome#GO:0048024;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000004330.3|UniProtKB=F7AMW5 F7AMW5 PTHR11758:SF16 40S RIBOSOMAL PROTEIN S15A 40S RIBOSOMAL PROTEIN S15A structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic small ribosomal subunit#GO:0022627;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;small ribosomal subunit#GO:0015935;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000003904.3|UniProtKB=F6T9K3 F6T9K3 LOC100182273 PTHR11467:SF36 HISTONE H1 HISTONE 24-RELATED nucleosome binding#GO:0031491;nucleic acid binding#GO:0003676;chromatin DNA binding#GO:0031490;binding#GO:0005488;organic cyclic compound binding#GO:0097159;chromatin binding#GO:0003682;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;protein-containing complex binding#GO:0044877 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA metabolic process#GO:0051052;chromosome condensation#GO:0030261;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;cellular process#GO:0009987;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA recombination#GO:0045910;negative regulation of DNA metabolic process#GO:0051053;regulation of DNA recombination#GO:0000018;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 CIOIN|Ensembl=ENSCING00000008383.3|UniProtKB=F6XSF3 F6XSF3 PTHR14950:SF37 DICER-RELATED ENDORIBONUCLEASE DICER CIOIN|Ensembl=ENSCING00000002488.3|UniProtKB=F6XYL2 F6XYL2 LOC100184498 PTHR46839:SF2 SUSHI DOMAIN-CONTAINING PROTEIN 6 SUSHI DOMAIN-CONTAINING PROTEIN 6 CIOIN|Ensembl=ENSCING00000004382.3|UniProtKB=F6YH21 F6YH21 PTHR22198:SF1 FERM DOMAIN-CONTAINING PROTEIN FERM DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000009293.3|UniProtKB=F7B9U5 F7B9U5 LOC100181141 PTHR22855:SF13 ACETYL, PROPIONYL, PYRUVATE, AND GLUTACONYL CARBOXYLASE-RELATED METHYLCROTONOYL-COA CARBOXYLASE BETA CHAIN, MITOCHONDRIAL ligase activity#GO:0016874;catalytic activity#GO:0003824 oxoacid metabolic process#GO:0043436;branched-chain amino acid metabolic process#GO:0009081;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;amino acid catabolic process#GO:0009063;small molecule catabolic process#GO:0044282;nitrogen compound metabolic process#GO:0006807;alpha-amino acid metabolic process#GO:1901605;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;carboxylic acid metabolic process#GO:0019752;amino acid metabolic process#GO:0006520;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 protein-containing complex#GO:0032991;catalytic complex#GO:1902494 ligase#PC00142;metabolite interconversion enzyme#PC00262 Methylmalonyl pathway#P02755>Propionyl-CoA carboxylase#P03033;Succinate to proprionate conversion#P02777>Methylmalonyl-CoA decarboxylase#P03163 CIOIN|Ensembl=ENSCING00000004328.3|UniProtKB=C4B8X2 C4B8X2 Ci-NDK_DPY26 PTHR46161:SF1 NUCLEOSIDE DIPHOSPHATE KINASE NUCLEOSIDE DIPHOSPHATE KINASE HOMOLOG 5 nucleotide kinase#PC00172 De novo purine biosynthesis#P02738>dADP kinase#P02907;De novo purine biosynthesis#P02738>GDP kinase#P02891 CIOIN|Ensembl=ENSCING00000009542.3|UniProtKB=F6U8Z7 F6U8Z7 LOC101242316 PTHR18919:SF107 ACETYL-COA C-ACYLTRANSFERASE ACETYL-COA ACETYLTRANSFERASE, CYTOSOLIC acyltransferase#PC00042 CIOIN|Ensembl=ENSCING00000011278.2|UniProtKB=F6Y9P8 F6Y9P8 PTHR12184:SF1 UBIQUINOL-CYTOCHROME C REDUCTASE COMPLEX ASSEMBLY FACTOR 1 FAMILY MEMBER UBIQUINOL-CYTOCHROME-C REDUCTASE COMPLEX ASSEMBLY FACTOR 1 chaperone#PC00072 CIOIN|Ensembl=ENSCING00000013171.2|UniProtKB=F6YF30 F6YF30 PTHR10768:SF0 60S RIBOSOMAL PROTEIN L37 RIBOSOMAL PROTEIN L37 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic large ribosomal subunit#GO:0022625;large ribosomal subunit#GO:0015934;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000008678.3|UniProtKB=F6XMI0 F6XMI0 tbx2_3 PTHR11267:SF181 T-BOX PROTEIN-RELATED OPTOMOTOR-BLIND PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;Rel homology transcription factor#PC00252;immunoglobulin fold transcription factor#PC00251 CIOIN|Ensembl=ENSCING00000018193.1|UniProtKB=H2XK36 H2XK36 PTHR12550:SF70 HEPATOMA-DERIVED GROWTH FACTOR-RELATED JIL-1 ANCHORING AND STABILIZING PROTEIN, ISOFORM A transcription cofactor#PC00217 CIOIN|Ensembl=ENSCING00000025210.1|UniProtKB=Q8HIN3 Q8HIN3 COIII PTHR11403:SF7 CYTOCHROME C OXIDASE SUBUNIT III CYTOCHROME C OXIDASE SUBUNIT 3 inorganic molecular entity transmembrane transporter activity#GO:0015318;transmembrane transporter activity#GO:0022857;primary active transmembrane transporter activity#GO:0015399;electron transfer activity#GO:0009055;catalytic activity#GO:0003824;proton transmembrane transporter activity#GO:0015078;active monoatomic ion transmembrane transporter activity#GO:0022853;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;inorganic cation transmembrane transporter activity#GO:0022890;active transmembrane transporter activity#GO:0022804;monoatomic ion transmembrane transporter activity#GO:0015075;oxidoreductase activity#GO:0016491 aerobic respiration#GO:0009060;cellular metabolic process#GO:0044237;cellular respiration#GO:0045333;cellular process#GO:0009987;energy derivation by oxidation of organic compounds#GO:0015980;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152 oxidase#PC00175;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000008074.3|UniProtKB=Q4H355 Q4H355 Ci-Neuralized-b PTHR12429:SF6 NEURALIZED PROTEIN NEURALIZED transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000020900.1|UniProtKB=H2XXR6 H2XXR6 PTHR24343:SF567 SERINE/THREONINE KINASE SERINE_THREONINE-PROTEIN KINASE BRSK2 ISOFORM X1 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;phosphorylation#GO:0016310;protein phosphorylation#GO:0006468;cellular process#GO:0009987;protein metabolic process#GO:0019538;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000005721.3|UniProtKB=F6RNF5 F6RNF5 LOC100180857 PTHR10676:SF36 DYNEIN HEAVY CHAIN FAMILY PROTEIN DYNEIN HEAVY CHAIN AT 93AB, ISOFORM C cytoskeletal motor activity#GO:0003774;microtubule motor activity#GO:0003777;protein binding#GO:0005515;ATP-dependent activity#GO:0140657;binding#GO:0005488 cilium-dependent cell motility#GO:0060285;microtubule-based process#GO:0007017;cilium or flagellum-dependent cell motility#GO:0001539;microtubule-based movement#GO:0007018;cell motility#GO:0048870;cellular process#GO:0009987;cilium movement involved in cell motility#GO:0060294;cilium movement#GO:0003341 axoneme#GO:0005930;catalytic complex#GO:1902494;cytoplasmic region#GO:0099568;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;microtubule associated complex#GO:0005875;non-membrane-bounded organelle#GO:0043228;motile cilium#GO:0031514;protein-containing complex#GO:0032991;9+2 motile cilium#GO:0097729;microtubule cytoskeleton#GO:0015630;ciliary plasm#GO:0097014;plasma membrane bounded cell projection cytoplasm#GO:0032838;membrane-bounded organelle#GO:0043227;dynein complex#GO:0030286;cell projection#GO:0042995;cytoskeleton#GO:0005856;cilium#GO:0005929 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 Huntington disease#P00029>Dynein complex#P00774 CIOIN|Ensembl=ENSCING00000004827.3|UniProtKB=F6R901 F6R901 PTHR13302:SF8 CONSERVED OLIGOMERIC GOLGI COMPLEX COMPONENT 3 CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 3 localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;Golgi organization#GO:0007030;establishment of localization#GO:0051234;intra-Golgi vesicle-mediated transport#GO:0006891;organelle organization#GO:0006996;transport#GO:0006810;endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;vesicle tethering complex#GO:0099023;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;Golgi transport complex#GO:0017119;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000003442.2|UniProtKB=F6U428 F6U428 LOC100176708 PTHR43477:SF4 DIHYDROANTICAPSIN 7-DEHYDROGENASE DEHYDROGENASE_REDUCTASE SDR FAMILY MEMBER 6 oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 dehydrogenase#PC00092;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000005086.3|UniProtKB=F6Z2X4 F6Z2X4 PTHR22455:SF10 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 91 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 91 CIOIN|Ensembl=ENSCING00000003063.3|UniProtKB=F6PPJ7 F6PPJ7 PTHR22504:SF0 REPRESSOR OF RNA POLYMERASE III TRANSCRIPTION MAF1 REPRESSOR OF RNA POLYMERASE III TRANSCRIPTION MAF1 HOMOLOG enzyme binding#GO:0019899;protein binding#GO:0005515;RNA polymerase binding#GO:0070063;binding#GO:0005488;RNA polymerase core enzyme binding#GO:0043175 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of biosynthetic process#GO:0009890;negative regulation of RNA metabolic process#GO:0051253;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of metabolic process#GO:0009892;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031;general transcription factor#PC00259 CIOIN|Ensembl=ENSCING00000012300.2|UniProtKB=F7AWH6 F7AWH6 PTHR10517:SF19 FOLATE RECEPTOR RETBINDIN signaling receptor activity#GO:0038023;transmembrane transporter activity#GO:0022857;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;heterocyclic compound binding#GO:1901363;molecular transducer activity#GO:0060089;ion binding#GO:0043167;anion binding#GO:0043168;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 membrane trafficking regulatory protein#PC00151 CIOIN|Ensembl=ENSCING00000010751.3|UniProtKB=F6ZDT1 F6ZDT1 PTHR12801:SF158 RNA EXONUCLEASE REXO1 / RECO3 FAMILY MEMBER-RELATED RNA EXONUCLEASE 4 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;exonuclease activity#GO:0004527;catalytic activity#GO:0003824 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031;exoribonuclease#PC00099 CIOIN|Ensembl=ENSCING00000007973.3|UniProtKB=F6WRK0 F6WRK0 PTHR12320:SF1 PROTEIN PHOSPHATASE 2C PROTEIN PHOSPHATASE PTC7 HOMOLOG hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;protein serine/threonine phosphatase activity#GO:0004722;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;dephosphorylation#GO:0016311;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein dephosphorylation#GO:0006470;cellular metabolic process#GO:0044237;cellular process#GO:0009987;protein metabolic process#GO:0019538;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 protein phosphatase#PC00195;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000018662.1|UniProtKB=H2XVS3 H2XVS3 zf(c2h2)-17 PTHR45888:SF5 HL01030P-RELATED D4, ISOFORM A CIOIN|Ensembl=ENSCING00000016765.2|UniProtKB=F6WF03 F6WF03 LOC100180390 PTHR22588:SF3 VWFA DOMAIN-CONTAINING PROTEIN VWFA DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000023162.1|UniProtKB=H2XWN3 H2XWN3 PTHR19325:SF567 COMPLEMENT COMPONENT-RELATED SUSHI DOMAIN-CONTAINING SUSHI, VON WILLEBRAND FACTOR TYPE A, EGF AND PENTRAXIN DOMAIN-CONTAINING PROTEIN 1-LIKE complement component#PC00078 CIOIN|Ensembl=ENSCING00000020581.1|UniProtKB=H2XVR4 H2XVR4 PTHR31849:SF1 CYSTEINE-RICH PDF MOTIF DOMAIN-CONTAINING PROTEIN 1 CYSTEINE-RICH DPF MOTIF DOMAIN-CONTAINING PROTEIN 1 CIOIN|Ensembl=ENSCING00000000305.3|UniProtKB=A0A1W5BIZ6 A0A1W5BIZ6 LOC100179663 PTHR12903:SF0 MITOCHONDRIAL RIBOSOMAL PROTEIN L24 LARGE RIBOSOMAL SUBUNIT PROTEIN UL24M macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;translation#GO:0006412;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 ribosomal protein#PC00202;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000017300.2|UniProtKB=F6PNS0 F6PNS0 PTHR45892:SF1 AMINOACYLASE-1 AMINOACYLASE-1 hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824 CIOIN|Ensembl=ENSCING00000009306.3|UniProtKB=F7A5Y1 F7A5Y1 PTHR24314:SF20 NON-SPECIFIC LIPID TRANSFER PROTEIN-RELATED STEROL CARRIER PROTEIN 2 transfer/carrier protein#PC00219 CIOIN|Ensembl=ENSCING00000010019.3|UniProtKB=F6QIE7 F6QIE7 PTHR12137:SF54 CARBOHYDRATE SULFOTRANSFERASE CARBOHYDRATE SULFOTRANSFERASE sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824 transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000019121.1|UniProtKB=H2XJY8 H2XJY8 PTHR11069:SF23 GLUCOSYLCERAMIDASE LYSOSOMAL ACID GLUCOSYLCERAMIDASE hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;carbohydrate derivative catabolic process#GO:1901136;glycolipid metabolic process#GO:0006664;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;lipid catabolic process#GO:0016042;cellular process#GO:0009987;liposaccharide metabolic process#GO:1903509;sphingolipid metabolic process#GO:0006665;primary metabolic process#GO:0044238;ceramide metabolic process#GO:0006672;membrane lipid metabolic process#GO:0006643;nitrogen compound metabolic process#GO:0006807;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;cellular lipid metabolic process#GO:0044255;sphingolipid catabolic process#GO:0030149;cellular lipid catabolic process#GO:0044242;amide metabolic process#GO:0043603;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 CIOIN|Ensembl=ENSCING00000001540.3|UniProtKB=F6Z3A0 F6Z3A0 LOC100179151 PTHR43917:SF8 FAMILY NOT NAMED GH16740P-RELATED transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000010070.3|UniProtKB=F6QCP0 F6QCP0 LOC101243099 PTHR46197:SF3 PROTEIN ABHD14B-LIKE AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000019420.1|UniProtKB=H2XJS5 H2XJS5 LOC100182790 PTHR34766:SF1 UPF0449 PROTEIN C19ORF25 UPF0449 PROTEIN C19ORF25 CIOIN|Ensembl=ENSCING00000009075.3|UniProtKB=F6QIL3 F6QIL3 pbx PTHR11850:SF108 HOMEOBOX PROTEIN TRANSCRIPTION FACTORS HOMEOBOX PROTEIN EXTRADENTICLE cellular developmental process#GO:0048869;neurogenesis#GO:0022008;animal organ development#GO:0048513;multicellular organism development#GO:0007275;developmental process#GO:0032502;cellular process#GO:0009987;nervous system development#GO:0007399;cell development#GO:0048468;system development#GO:0048731;embryonic organ development#GO:0048568;cell differentiation#GO:0030154;embryo development#GO:0009790;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;neuron differentiation#GO:0030182;animal organ morphogenesis#GO:0009887;neuron development#GO:0048666;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 CIOIN|Ensembl=ENSCING00000013599.2|UniProtKB=F6VPF4 F6VPF4 LOC100187343 PTHR30289:SF8 UNCHARACTERIZED PROTEIN YBCL-RELATED YHYH DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000003342.3|UniProtKB=F6S146 F6S146 smyd1 PTHR12197:SF184 HISTONE-LYSINE N-METHYLTRANSFERASE SMYD HISTONE-LYSINE N-METHYLTRANSFERASE SMYD1 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 histone modifying enzyme#PC00261 CIOIN|Ensembl=ENSCING00000001724.3|UniProtKB=F6TVE9 F6TVE9 zf(c2h2)-26 PTHR24388:SF28 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 341 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 CIOIN|Ensembl=ENSCING00000003407.3|UniProtKB=F6ZMD2 F6ZMD2 not1 PTHR34721:SF3 PROTEIN CBG09734 ACTIVIN_RECP DOMAIN-CONTAINING PROTEIN-RELATED CIOIN|Ensembl=ENSCING00000001124.3|UniProtKB=F6ZDB4 F6ZDB4 LOC100183995 PTHR12144:SF0 NEGATIVE ELONGATION FACTOR D NEGATIVE ELONGATION FACTOR C_D nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 regulation of DNA-templated transcription elongation#GO:0032784;regulation of transcription elongation by RNA polymerase II#GO:0034243;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of biosynthetic process#GO:0009890;negative regulation of RNA metabolic process#GO:0051253;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of metabolic process#GO:0009892;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;transcription elongation factor complex#GO:0008023;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000013717.2|UniProtKB=F6PMS1 F6PMS1 LOC100181757 PTHR15066:SF0 TRANSMEMBRANE PROTEIN 187 TRANSMEMBRANE PROTEIN 187 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;transport vesicle#GO:0030133;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000004650.3|UniProtKB=F6RLR6 F6RLR6 PTHR24300:SF397 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 2U1 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;tetrapyrrole binding#GO:0046906;steroid hydroxylase activity#GO:0008395;oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497;heme binding#GO:0020037 response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;response to chemical#GO:0042221;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 oxygenase#PC00177;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000021001.1|UniProtKB=H2XUF9 H2XUF9 PTHR10845:SF259 REGULATOR OF G PROTEIN SIGNALING RGS DOMAIN-CONTAINING PROTEIN-RELATED G-protein modulator#PC00022;protein-binding activity modulator#PC00095;GTPase-activating protein#PC00257 CIOIN|Ensembl=ENSCING00000018434.1|UniProtKB=H2XQ81 H2XQ81 PTHR12416:SF2 RRNA-PROCESSING PROTEIN UTP23 HOMOLOG RRNA-PROCESSING PROTEIN FCF1 HOMOLOG membrane-enclosed lumen#GO:0031974;small-subunit processome#GO:0032040;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;nuclear lumen#GO:0031981 CIOIN|Ensembl=ENSCING00000004393.3|UniProtKB=F7AUI4 F7AUI4 zf(c2h2)-1 PTHR23226:SF416 ZINC FINGER AND SCAN DOMAIN-CONTAINING FI01424P C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 CIOIN|Ensembl=ENSCING00000005807.3|UniProtKB=F6RGE7 F6RGE7 LOC100176818 PTHR45684:SF2 RE74312P RE74312P pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824 endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;membrane organization#GO:0061024;transport#GO:0006810;regulation of localization#GO:0032879;regulation of cellular component organization#GO:0051128;regulation of biological process#GO:0050789;regulation of transport#GO:0051049;regulation of protein-containing complex assembly#GO:0043254;establishment of localization#GO:0051234;regulation of cellular component biogenesis#GO:0044087;positive regulation of protein transport#GO:0051222;vesicle organization#GO:0016050;regulation of protein transport#GO:0051223;positive regulation of biological process#GO:0048518;regulation of protein localization#GO:0032880;positive regulation of establishment of protein localization#GO:1904951;regulation of organelle organization#GO:0033043;positive regulation of transport#GO:0051050;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;Golgi vesicle transport#GO:0048193;regulation of cellular localization#GO:0060341;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;positive regulation of protein localization#GO:1903829;regulation of establishment of protein localization#GO:0070201 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;ER to Golgi transport vesicle membrane#GO:0012507;COPII-coated ER to Golgi transport vesicle#GO:0030134;endoplasmic reticulum exit site#GO:0070971;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;coated vesicle#GO:0030135;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;vesicle coat#GO:0030120;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;transport vesicle membrane#GO:0030658;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;coated vesicle membrane#GO:0030662;membrane coat#GO:0030117;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;coated membrane#GO:0048475;transport vesicle#GO:0030133;cytoplasmic vesicle membrane#GO:0030659;endoplasmic reticulum#GO:0005783 CIOIN|Ensembl=ENSCING00000024400.1|UniProtKB=H2Y2D9 H2Y2D9 PTHR24300:SF397 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 2U1 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;tetrapyrrole binding#GO:0046906;steroid hydroxylase activity#GO:0008395;oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497;heme binding#GO:0020037 response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;response to chemical#GO:0042221;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 oxygenase#PC00177;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000020727.1|UniProtKB=F6YWH4 F6YWH4 LOC100180061 PTHR12653:SF0 NADH-UBIQUINONE OXIDOREDUCTASE 13 KD-B SUBUNIT NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 5 cellular respiration#GO:0045333;respiratory electron transport chain#GO:0022904;generation of precursor metabolites and energy#GO:0006091;cellular metabolic process#GO:0044237;electron transport chain#GO:0022900;cellular process#GO:0009987;energy derivation by oxidation of organic compounds#GO:0015980;metabolic process#GO:0008152 envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;respiratory chain complex#GO:0098803;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transporter complex#GO:1990351;oxidoreductase complex#GO:1990204;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;respirasome#GO:0070469;mitochondrial respiratory chain complex I#GO:0005747;protein-containing complex#GO:0032991;mitochondrial envelope#GO:0005740;mitochondrial respirasome#GO:0005746;transmembrane transporter complex#GO:1902495;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227;respiratory chain complex I#GO:0045271;NADH dehydrogenase complex#GO:0030964;mitochondrial protein-containing complex#GO:0098798 oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000010010.3|UniProtKB=F6QM26 F6QM26 PTHR21678:SF0 GROWTH INHIBITION AND DIFFERENTIATION RELATED PROTEIN 88 C3H1-TYPE DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000004524.3|UniProtKB=F6S095 F6S095 PTHR23308:SF66 NUCLEAR INHIBITOR OF PROTEIN PHOSPHATASE-1 KANADAPTIN nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 RNA splicing factor#PC00148;RNA processing factor#PC00147 CIOIN|Ensembl=ENSCING00000014797.2|UniProtKB=F6VLB0 F6VLB0 PTHR46785:SF1 VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 3B VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 3B CIOIN|Ensembl=ENSCING00000017628.2|UniProtKB=F6ZET9 F6ZET9 PTHR47977:SF39 RAS-RELATED PROTEIN RAB SUBFAMILY NOT NAMED GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;ion binding#GO:0043167;anion binding#GO:0043168 localization#GO:0051179;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization#GO:0051234;transport#GO:0006810 small GTPase#PC00208;G-protein#PC00020 CIOIN|Ensembl=ENSCING00000009741.3|UniProtKB=F6TIH0 F6TIH0 LOC100183825 PTHR23423:SF21 ORGANIC SOLUTE TRANSPORTER-RELATED ORGANIC SOLUTE TRANSPORTER SUBUNIT ALPHA-LIKE localization#GO:0051179;establishment of localization#GO:0051234;transport#GO:0006810 cellular anatomical entity#GO:0110165;membrane#GO:0016020 transporter#PC00227 CIOIN|Ensembl=ENSCING00000010954.3|UniProtKB=F7AZA1 F7AZA1 LOC100179502 PTHR45910:SF1 N-ALPHA-ACETYLTRANSFERASE 20 N-ALPHA-ACETYLTRANSFERASE 20 acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;N-acetyltransferase activity#GO:0008080;acetyltransferase activity#GO:0016407;peptide N-acetyltransferase activity#GO:0034212;catalytic activity#GO:0003824;peptide alpha-N-acetyltransferase activity#GO:0004596;N-acyltransferase activity#GO:0016410 macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;protein modification process#GO:0036211;gene expression#GO:0010467;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;protein acylation#GO:0043543;cellular process#GO:0009987;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;protein acetylation#GO:0006473;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;protein acetyltransferase complex#GO:0031248;protein-containing complex#GO:0032991;acetyltransferase complex#GO:1902493;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 acetyltransferase#PC00038 CIOIN|Ensembl=ENSCING00000003313.3|UniProtKB=F6TBD1 F6TBD1 PTHR23503:SF132 SOLUTE CARRIER FAMILY 2 SOLUTE CARRIER FAMILY 2, FACILITATED GLUCOSE TRANSPORTER MEMBER 5-LIKE transmembrane transporter activity#GO:0022857;sugar transmembrane transporter activity#GO:0051119;transporter activity#GO:0005215;carbohydrate transmembrane transporter activity#GO:0015144 localization#GO:0051179;organic substance transport#GO:0071702;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;organic anion transport#GO:0015711;transport#GO:0006810;vitamin transport#GO:0051180;glucose transmembrane transport#GO:1904659;cellular process#GO:0009987;carbohydrate transmembrane transport#GO:0034219;carbohydrate transport#GO:0008643 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000001803.3|UniProtKB=F6X5I5 F6X5I5 PTHR11006:SF73 PROTEIN ARGININE N-METHYLTRANSFERASE PROTEIN ARGININE N-METHYLTRANSFERASE 6 N-methyltransferase activity#GO:0008170;histone modifying activity#GO:0140993;transferase activity#GO:0016740;catalytic activity#GO:0003824;histone methyltransferase activity#GO:0042054;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a protein#GO:0140096;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;protein methyltransferase activity#GO:0008276 protein-DNA complex organization#GO:0071824;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular component organization#GO:0016043;peptidyl-amino acid modification#GO:0018193;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;methylation#GO:0032259;macromolecule methylation#GO:0043414;nitrogen compound metabolic process#GO:0006807;protein-containing complex organization#GO:0043933;chromatin organization#GO:0006325;chromatin remodeling#GO:0006338;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000005458.3|UniProtKB=F6UTR1 F6UTR1 LOC100186271 PTHR15623:SF11 SPERMATOGENESIS-ASSOCIATED SERINE-RICH PROTEIN 2-RELATED SPERMATOGENESIS-ASSOCIATED SERINE-RICH PROTEIN 2 CIOIN|Ensembl=ENSCING00000020027.1|UniProtKB=H2XYH1 H2XYH1 LOC100182376 PTHR43205:SF7 PROSTAGLANDIN REDUCTASE PROSTAGLANDIN REDUCTASE 1 reductase#PC00198;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000005220.3|UniProtKB=F6Z0U1 F6Z0U1 PTHR10977:SF3 DIPHOSPHOMEVALONATE DECARBOXYLASE DIPHOSPHOMEVALONATE DECARBOXYLASE decarboxylase#PC00089 Cholesterol biosynthesis#P00014>Diphosphomevalonate decarboxylase#P00496 CIOIN|Ensembl=ENSCING00000001312.3|UniProtKB=F6WW43 F6WW43 LOC100180302 PTHR31663:SF6 COILED-COIL DOMAIN-CONTAINING PROTEIN 3 COILED-COIL DOMAIN-CONTAINING PROTEIN 3-LIKE CIOIN|Ensembl=ENSCING00000015661.1|UniProtKB=F6X545 F6X545 LOC100186803 PTHR10671:SF108 EPITHELIAL MEMBRANE PROTEIN-RELATED CLAUDIN FAMILY PROTEIN-RELATED cytoskeletal protein#PC00085 CIOIN|Ensembl=ENSCING00000006203.3|UniProtKB=F6YVH4 F6YVH4 PTHR24299:SF21 CYTOCHROME P450 FAMILY 1 OS09G0441600 PROTEIN oxygenase#PC00177;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000006714.3|UniProtKB=F7A7X6 F7A7X6 PTHR45701:SF3 SYNAPTOBREVIN FAMILY MEMBER SYNAPTOBREVIN syntaxin binding#GO:0019905;molecular adaptor activity#GO:0060090;protein binding#GO:0005515;SNAP receptor activity#GO:0005484;binding#GO:0005488;SNARE binding#GO:0000149;protein-macromolecule adaptor activity#GO:0030674 localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;vesicle fusion#GO:0006906;membrane fusion#GO:0061025;establishment of localization#GO:0051234;membrane organization#GO:0061024;organelle organization#GO:0006996;organelle membrane fusion#GO:0090174;transport#GO:0006810;vesicle-mediated transport#GO:0016192;vesicle organization#GO:0016050;cellular component organization#GO:0016043;cellular process#GO:0009987;organelle fusion#GO:0048284 cytoplasm#GO:0005737;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;SNARE complex#GO:0031201;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150 Opioid proenkephalin pathway#P05915>SNARE Complex#P05986;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>SNARE Complex#P01066;Thyrotropin-releasing hormone receptor signaling pathway#P04394>SNARE Complex#P04582;Dopamine receptor mediated signaling pathway#P05912>SNARE Complex#P05956;Adrenaline and noradrenaline biosynthesis#P00001>SNARE#P00072;Beta3 adrenergic receptor signaling pathway#P04379>SNARE Complex#P04447;5HT4 type receptor mediated signaling pathway#P04376>SNARE Complex#P04428;Opioid prodynorphin pathway#P05916>SNARE Complex#P05996;Alpha adrenergic receptor signaling pathway#P00002>SNARE#P00074;Nicotinic acetylcholine receptor signaling pathway#P00044>SNARE Complex#P01091;5HT3 type receptor mediated signaling pathway#P04375>SNARE Complex#P04423;Ionotropic glutamate receptor pathway#P00037>SNARE Complex#P01013;Metabotropic glutamate receptor group II pathway#P00040>SNARE Complex#P01049;Opioid proopiomelanocortin pathway#P05917>SNARE Complex#P06005;Beta1 adrenergic receptor signaling pathway#P04377>SNARE Complex#P04435;Cortocotropin releasing factor receptor signaling pathway#P04380>SNARE Complex#P04457;Metabotropic glutamate receptor group III pathway#P00039>SNARE Complex#P01042;Oxytocin receptor mediated signaling pathway#P04391>SNARE Complex#P04532;5HT2 type receptor mediated signaling pathway#P04374>SNARE Complex#P04415;5HT1 type receptor mediated signaling pathway#P04373>SNARE Complex#P04405;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>SNARE Complex#P01079;Beta2 adrenergic receptor signaling pathway#P04378>SNARE Complex#P04442 CIOIN|Ensembl=ENSCING00000006770.3|UniProtKB=F6XAQ8 F6XAQ8 PTHR44216:SF3 PROTEIN O-MANNOSYL-TRANSFERASE TMTC2 PROTEIN O-MANNOSYL-TRANSFERASE TMTC2 protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000001997.3|UniProtKB=F6XFL4 F6XFL4 PTHR12265:SF30 TRANSMEMBRANE PROTEIN 53 TRANSMEMBRANE PROTEIN 53 CIOIN|Ensembl=ENSCING00000006100.3|UniProtKB=F6YX42 F6YX42 LOC100177419 PTHR11371:SF33 DEOXYRIBONUCLEASE ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN hydrolase activity, acting on ester bonds#GO:0016788;DNA endonuclease activity#GO:0004520;nucleic acid binding#GO:0003676;nuclease activity#GO:0004518;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;hydrolase activity#GO:0016787;catalytic activity, acting on a nucleic acid#GO:0140640;endonuclease activity#GO:0004519;catalytic activity, acting on DNA#GO:0140097;DNA nuclease activity#GO:0004536 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;heterocycle catabolic process#GO:0046700;macromolecule metabolic process#GO:0043170;DNA catabolic process#GO:0006308;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular nitrogen compound catabolic process#GO:0044270;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;organic cyclic compound catabolic process#GO:1901361;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;nucleobase-containing compound catabolic process#GO:0034655;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259;cellular catabolic process#GO:0044248 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 endodeoxyribonuclease#PC00093 CIOIN|Ensembl=ENSCING00000009552.3|UniProtKB=F6U8G8 F6U8G8 PTHR43053:SF4 GLYCOSIDASE FAMILY 31 MYOGENESIS-REGULATING GLYCOSIDASE glucosidase#PC00108 CIOIN|Ensembl=ENSCING00000009502.3|UniProtKB=F6Y8V9 F6Y8V9 PTHR13723:SF293 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE A DISINTEGRIN AND METALLOPROTEINASE WITH THROMBOSPONDIN MOTIFS 18 hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular component organization or biogenesis#GO:0071840;extracellular structure organization#GO:0043062;external encapsulating structure organization#GO:0045229;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;cellular component organization#GO:0016043;cellular process#GO:0009987;protein metabolic process#GO:0019538;extracellular matrix organization#GO:0030198;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944 metalloprotease#PC00153;protease#PC00190 CIOIN|Ensembl=ENSCING00000002791.3|UniProtKB=F6XMY3 F6XMY3 LOC100185062 PTHR12059:SF5 RIBOSOMAL PROTEIN L23-RELATED LARGE RIBOSOMAL SUBUNIT PROTEIN UL23M structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;mitochondrial gene expression#GO:0140053;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;mitochondrial translation#GO:0032543;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;mitochondrial large ribosomal subunit#GO:0005762;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;mitochondrial ribosome#GO:0005761;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;ribosomal subunit#GO:0044391;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;organellar ribosome#GO:0000313;protein-containing complex#GO:0032991;large ribosomal subunit#GO:0015934;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;ribosome#GO:0005840;mitochondrial protein-containing complex#GO:0098798 ribosomal protein#PC00202;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000013644.2|UniProtKB=F6UC03 F6UC03 LOC100183694 PTHR20951:SF2 C13ORF1 PROTEIN-RELATED SPRY DOMAIN-CONTAINING PROTEIN 7 CIOIN|Ensembl=ENSCING00000008610.3|UniProtKB=F6TNV5 F6TNV5 LOC100184121 PTHR44490:SF1 EUKARYOTIC TRANSLATION ELONGATION FACTOR 1 EPSILON-1 EUKARYOTIC TRANSLATION ELONGATION FACTOR 1 EPSILON-1 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 translation elongation factor#PC00222;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000001093.3|UniProtKB=F7AZQ8 F7AZQ8 PTHR14139:SF2 CALSYNTENIN CALSYNTENIN-1 membrane traffic protein#PC00150 CIOIN|Ensembl=ENSCING00000014452.2|UniProtKB=F6YB21 F6YB21 LOC100180220 PTHR10369:SF3 60S RIBOSOMAL PROTEIN L36A/L44 RIBOSOMAL PROTEIN L36A LIKE cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic large ribosomal subunit#GO:0022625;large ribosomal subunit#GO:0015934;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000007486.3|UniProtKB=F6XWF2 F6XWF2 rhamm PTHR18956:SF6 HYALURONAN MEDIATED MOTILITY RECEPTOR HYALURONAN MEDIATED MOTILITY RECEPTOR CIOIN|Ensembl=ENSCING00000014249.2|UniProtKB=F6T6J2 F6T6J2 LOC100176092 PTHR12411:SF586 CYSTEINE PROTEASE FAMILY C1-RELATED CATHEPSIN L-LIKE cysteine-type peptidase activity#GO:0008234;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197 macromolecule catabolic process#GO:0009057;nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;proteolysis#GO:0006508;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;catabolic process#GO:0009056;organonitrogen compound catabolic process#GO:1901565;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;primary metabolic process#GO:0044238 cytoplasm#GO:0005737;lysosome#GO:0005764;intracellular membrane-bounded organelle#GO:0043231;extracellular region#GO:0005576;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;organelle#GO:0043226;lytic vacuole#GO:0000323;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cysteine protease#PC00081;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000004297.3|UniProtKB=F6TTB4 F6TTB4 PTHR45710:SF26 C-TYPE LECTIN DOMAIN-CONTAINING PROTEIN 180 RH26557P defense/immunity protein#PC00090 CIOIN|Ensembl=ENSCING00000009620.3|UniProtKB=F7ACL3 F7ACL3 PTHR24034:SF198 EGF-LIKE DOMAIN-CONTAINING PROTEIN FIBRILLIN-1-LIKE extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 CIOIN|Ensembl=ENSCING00000001638.3|UniProtKB=F7B7S4 F7B7S4 PTHR24412:SF497 KELCH PROTEIN KELCH-LIKE PROTEIN 18 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000007710.3|UniProtKB=F7A2I6 F7A2I6 PTHR13559:SF1 INTRACELLULAR TRAFFIC PROTEIN-RELATED PROTEIN FUZZY HOMOLOG organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782;cellular component assembly#GO:0022607;non-motile cilium assembly#GO:1905515;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cell projection organization#GO:0030030;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031 CIOIN|Ensembl=ENSCING00000014604.2|UniProtKB=F6SY14 F6SY14 PTHR16165:SF5 NXPE FAMILY MEMBER NXPE FAMILY MEMBER 3 CIOIN|Ensembl=ENSCING00000014597.2|UniProtKB=F6SYB9 F6SYB9 PTHR12378:SF7 DESUMOYLATING ISOPEPTIDASE DESUMOYLATING ISOPEPTIDASE 1 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;protein modification by small protein removal#GO:0070646;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;post-translational protein modification#GO:0043687;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;primary metabolic process#GO:0044238;metabolic process#GO:0008152 cysteine protease#PC00081;protease#PC00190 CIOIN|Ensembl=ENSCING00000006436.3|UniProtKB=F6QLM7 F6QLM7 PTHR10410:SF6 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 -RELATED COP9 SIGNALOSOME COMPLEX SUBUNIT 5 hydrolase activity#GO:0016787;ubiquitin-like protein peptidase activity#GO:0019783;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;protein modification by small protein removal#GO:0070646;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;post-translational protein modification#GO:0043687;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;COP9 signalosome#GO:0008180;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622 translation initiation factor#PC00224;translation factor#PC00223 PDGF signaling pathway#P00047>c-Jun#P01163 CIOIN|Ensembl=ENSCING00000023628.1|UniProtKB=H2Y0H5 H2Y0H5 PTHR47966:SF51 BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;aspartic-type endopeptidase activity#GO:0004190;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 aspartic protease#PC00053;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000008263.3|UniProtKB=F6QW56 F6QW56 PTHR10338:SF108 INTER-ALPHA-TRYPSIN INHIBITOR HEAVY CHAIN FAMILY MEMBER INTER-ALPHA-TRYPSIN INHIBITOR HEAVY CHAIN H4-LIKE PROTEIN protease inhibitor#PC00191;protein-binding activity modulator#PC00095 CIOIN|Ensembl=ENSCING00000013657.2|UniProtKB=F6UB97 F6UB97 PTHR12192:SF26 CATION TRANSPORT PROTEIN CHAC-RELATED GLUTATHIONE-SPECIFIC GAMMA-GLUTAMYLCYCLOTRANSFERASE 1 lyase activity#GO:0016829;catalytic activity#GO:0003824 sulfur compound metabolic process#GO:0006790;peptide metabolic process#GO:0006518;organonitrogen compound metabolic process#GO:1901564;peptide catabolic process#GO:0043171;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;glutathione metabolic process#GO:0006749;sulfur compound catabolic process#GO:0044273;nitrogen compound metabolic process#GO:0006807;cellular modified amino acid metabolic process#GO:0006575;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000005161.3|UniProtKB=F6SKS5 F6SKS5 LOC100179962 PTHR12928:SF0 FRG1 PROTEIN FSHD REGION GENE 1 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 membrane-enclosed lumen#GO:0031974;supramolecular complex#GO:0099080;catalytic step 2 spliceosome#GO:0071013;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;organelle#GO:0043226;contractile fiber#GO:0043292;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 RNA splicing factor#PC00148;RNA processing factor#PC00147;RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000007587.3|UniProtKB=F7A405 F7A405 LOC100175085 PTHR34262:SF1 TRANSMEMBRANE PROTEIN 220 TRANSMEMBRANE PROTEIN 220 CIOIN|Ensembl=ENSCING00000005017.3|UniProtKB=F6TAP2 F6TAP2 PTHR45638:SF11 CYCLIC NUCLEOTIDE-GATED CATION CHANNEL SUBUNIT A CYCLIC NUCLEOTIDE-GATED CATION CHANNEL SUBUNIT A protein-containing complex binding#GO:0044877;binding#GO:0005488 ligand-gated ion channel#PC00141;ion channel#PC00133;transporter#PC00227 CIOIN|Ensembl=ENSCING00000007064.3|UniProtKB=F6WWD5 F6WWD5 LOC100177022 PTHR23075:SF0 PUTATIVE ATP-ASE ATPASE FAMILY AAA DOMAIN-CONTAINING PROTEIN 3 cation binding#GO:0043169;metal ion binding#GO:0046872;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;zinc ion binding#GO:0008270;transition metal ion binding#GO:0046914 cellular component organization or biogenesis#GO:0071840;mitochondrion organization#GO:0007005;cellular component organization#GO:0016043;cellular process#GO:0009987;organelle organization#GO:0006996 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000011763.2|UniProtKB=F6T9X3 F6T9X3 LOC100176127 PTHR19325:SF567 COMPLEMENT COMPONENT-RELATED SUSHI DOMAIN-CONTAINING SUSHI, VON WILLEBRAND FACTOR TYPE A, EGF AND PENTRAXIN DOMAIN-CONTAINING PROTEIN 1-LIKE complement component#PC00078 CIOIN|Ensembl=ENSCING00000024575.1|UniProtKB=Q6A1F0 Q6A1F0 ona14 PTHR11929:SF145 ALPHA- 1,3 -FUCOSYLTRANSFERASE ALPHA-(1,3)-FUCOSYLTRANSFERASE FUT-1 transferase activity#GO:0016740;fucosyltransferase activity#GO:0008417;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 glycosylation#GO:0070085;metabolic process#GO:0008152 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000012867.2|UniProtKB=F6PZD7 F6PZD7 PTHR10229:SF0 GTP-BINDING PROTEIN HFLX GTP-BINDING PROTEIN 6-RELATED ribonucleoprotein complex binding#GO:0043021;ribosome binding#GO:0043022;protein-containing complex binding#GO:0044877;binding#GO:0005488 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000017588.2|UniProtKB=F6ZNJ4 F6ZNJ4 LOC100181252 PTHR19300:SF57 BETA-1,4-GALACTOSYLTRANSFERASE BETA-1,4-N-ACETYLGALACTOSAMINYLTRANSFERASE galactosyltransferase activity#GO:0008378;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 glycosylation#GO:0070085;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000023382.1|UniProtKB=H2XRF3 H2XRF3 PTHR45746:SF6 LP21163P LP21163P nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 regulation of cell communication#GO:0010646;regulation of GTPase activity#GO:0043087;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;regulation of G protein-coupled receptor signaling pathway#GO:0008277;regulation of catalytic activity#GO:0050790;positive regulation of hydrolase activity#GO:0051345;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of hydrolase activity#GO:0051336 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>RGS#P00704;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>RGS#P00731 CIOIN|Ensembl=ENSCING00000012007.2|UniProtKB=F7B7K2 F7B7K2 LOC100180699 PTHR10114:SF0 60S RIBOSOMAL PROTEIN L36 LARGE RIBOSOMAL SUBUNIT PROTEIN EL36 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cytoplasmic translation#GO:0002181;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic large ribosomal subunit#GO:0022625;large ribosomal subunit#GO:0015934;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000005232.3|UniProtKB=F6YHS8 F6YHS8 PTHR10855:SF1 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 12/COP9 SIGNALOSOME COMPLEX SUBUNIT 4 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 12 cytoplasm#GO:0005737;peptidase complex#GO:1905368;protein-containing complex#GO:0032991;proteasome accessory complex#GO:0022624;proteasome regulatory particle#GO:0005838;catalytic complex#GO:1902494;proteasome regulatory particle, lid subcomplex#GO:0008541;endopeptidase complex#GO:1905369;proteasome complex#GO:0000502;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 protease#PC00190 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489;Cell cycle#P00013>Proteasome#P00480 CIOIN|Ensembl=ENSCING00000013016.2|UniProtKB=F6UGQ7 F6UGQ7 PTHR24096:SF149 LONG-CHAIN-FATTY-ACID--COA LIGASE AMP-BINDING DOMAIN-CONTAINING PROTEIN-RELATED ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877 metabolite interconversion enzyme#PC00262;ligase#PC00142 CIOIN|Ensembl=ENSCING00000014285.2|UniProtKB=A0A1W2WGH4 A0A1W2WGH4 LOC100177394 PTHR16127:SF13 TAXILIN GH01188P membrane traffic protein#PC00150 CIOIN|Ensembl=ENSCING00000002651.3|UniProtKB=F6YDK0 F6YDK0 PTHR21243:SF15 PROTEIN SCAI PROTEIN SCAI transcription coregulator activity#GO:0003712;molecular adaptor activity#GO:0060090;transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714;protein-macromolecule adaptor activity#GO:0030674 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000011845.2|UniProtKB=F6V879 F6V879 PTHR44404:SF1 HYDROXYSTEROID DEHYDROGENASE 1M HYDROXYSTEROID 11-BETA-DEHYDROGENASE 1-LIKE PROTEIN dehydrogenase#PC00092;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000006776.3|UniProtKB=F6VEI9 F6VEI9 LOC100178966 PTHR21442:SF0 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 206 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 206 biological regulation#GO:0065007;regulation of biological process#GO:0050789;regulation of microtubule-based process#GO:0032886;regulation of cellular process#GO:0050794 axoneme#GO:0005930;microtubule organizing center#GO:0005815;cytoplasmic region#GO:0099568;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;ciliary basal body#GO:0036064;membrane-bounded organelle#GO:0043227;plasma membrane bounded cell projection cytoplasm#GO:0032838;ciliary plasm#GO:0097014;cell projection#GO:0042995;cytoskeleton#GO:0005856;cilium#GO:0005929 CIOIN|Ensembl=ENSCING00000023407.1|UniProtKB=H2Y0G2 H2Y0G2 LOC100186781 PTHR23050:SF169 CALCIUM BINDING PROTEIN CALMODULIN-LIKE PROTEIN 4 cation binding#GO:0043169;small molecule binding#GO:0036094;molecular function regulator activity#GO:0098772;binding#GO:0005488;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;enzyme regulator activity#GO:0030234 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 calmodulin-related#PC00061 CIOIN|Ensembl=ENSCING00000018217.1|UniProtKB=H2XP66 H2XP66 PTHR10827:SF95 RETICULOCALBIN LD34388P cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 calmodulin-related#PC00061 CIOIN|Ensembl=ENSCING00000006581.3|UniProtKB=F6R0U8 F6R0U8 LOC100178266 PTHR24073:SF839 DRAB5-RELATED RAS-RELATED PROTEIN RAB-38 GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824 cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;pigmentation#GO:0043473;nitrogen compound transport#GO:0071705;cellular component organization#GO:0016043;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;organelle organization#GO:0006996;protein transport#GO:0015031;melanosome organization#GO:0032438;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;vesicle organization#GO:0016050;intracellular transport#GO:0046907 trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;organelle subcompartment#GO:0031984;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;melanosome#GO:0042470;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;Golgi apparatus subcompartment#GO:0098791 small GTPase#PC00208;G-protein#PC00020 CIOIN|Ensembl=ENSCING00000003880.3|UniProtKB=F6TXG4 F6TXG4 LOC100181802 PTHR24064:SF577 SOLUTE CARRIER FAMILY 22 MEMBER GH09241P secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000013698.2|UniProtKB=F6PRT8 F6PRT8 PTHR38926:SF72 F-BOX DOMAIN CONTAINING PROTEIN, EXPRESSED IM:7136021-RELATED CIOIN|Ensembl=ENSCING00000000079.3|UniProtKB=Q1RLB1 Q1RLB1 Ci-ZF(Bbox_RING)-6 PTHR24103:SF681 E3 UBIQUITIN-PROTEIN LIGASE TRIM TRIPARTITE MOTIF-CONTAINING PROTEIN 55-LIKE ISOFORM X1 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234 CIOIN|Ensembl=ENSCING00000007950.3|UniProtKB=F6Z8G0 F6Z8G0 PTHR24343:SF540 SERINE/THREONINE KINASE SERINE_THREONINE-PROTEIN KINASE CHK1 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;phosphorylation#GO:0016310;protein phosphorylation#GO:0006468;cellular process#GO:0009987;protein metabolic process#GO:0019538;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000008519.3|UniProtKB=F7AI88 F7AI88 LOC100187236 PTHR10603:SF7 FRAGILE X MENTAL RETARDATION SYNDROME-RELATED PROTEIN FRAGILE X MESSENGER RIBONUCLEOPROTEIN 1 HOMOLOG RNA binding#GO:0003723;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159;mRNA 3'-UTR binding#GO:0003730 positive regulation of gene expression#GO:0010628;positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of protein metabolic process#GO:0051246;regulation of amide metabolic process#GO:0034248;regulation of mRNA stability#GO:0043488;regulation of mRNA catabolic process#GO:0061013;regulation of catabolic process#GO:0009894;macromolecule localization#GO:0033036;regulation of nitrogen compound metabolic process#GO:0051171;animal organ development#GO:0048513;positive regulation of cellular metabolic process#GO:0031325;transport#GO:0006810;developmental process#GO:0032502;nucleic acid transport#GO:0050657;nitrogen compound transport#GO:0071705;RNA localization#GO:0006403;regulation of biological process#GO:0050789;organic substance transport#GO:0071702;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;regulation of biosynthetic process#GO:0009889;RNA transport#GO:0050658;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;positive regulation of translation#GO:0045727;establishment of RNA localization#GO:0051236;positive regulation of cellular biosynthetic process#GO:0031328;regulation of cellular catabolic process#GO:0031329;regulation of RNA stability#GO:0043487;positive regulation of macromolecule metabolic process#GO:0010604;mRNA transport#GO:0051028;regulation of RNA metabolic process#GO:0051252;positive regulation of cellular process#GO:0048522;localization#GO:0051179;regulation of primary metabolic process#GO:0080090;positive regulation of protein metabolic process#GO:0051247;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;nucleobase-containing compound transport#GO:0015931;post-transcriptional regulation of gene expression#GO:0010608;anatomical structure development#GO:0048856;biological regulation#GO:0065007;regulation of translation#GO:0006417;regulation of metabolic process#GO:0019222;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytoplasmic stress granule#GO:0010494;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic ribonucleoprotein granule#GO:0036464 translation factor#PC00223 CIOIN|Ensembl=ENSCING00000014902.2|UniProtKB=F6XKQ6 F6XKQ6 LOC100181581 PTHR32379:SF1 GUANIDINOACETATE N-METHYLTRANSFERASE GUANIDINOACETATE N-METHYLTRANSFERASE methyltransferase activity#GO:0008168;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 methyltransferase#PC00155;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000003433.3|UniProtKB=F6XL41 F6XL41 LOC100181376 PTHR21049:SF0 RIBOPHORIN I DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT 1 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein N-linked glycosylation#GO:0006487;protein metabolic process#GO:0019538;protein N-linked glycosylation via asparagine#GO:0018279;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 membrane protein complex#GO:0098796;endoplasmic reticulum protein-containing complex#GO:0140534;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endoplasmic reticulum subcompartment#GO:0098827;oligosaccharyltransferase complex#GO:0008250;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 glycosyltransferase#PC00111 CIOIN|Ensembl=ENSCING00000021720.1|UniProtKB=H2XTI3 H2XTI3 PTHR45672:SF2 PROTEIN DISULFIDE-ISOMERASE C17H9.14C-RELATED PROTEIN DISULFIDE-ISOMERASE A5 isomerase activity#GO:0016853;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;protein disulfide isomerase activity#GO:0003756 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein folding#GO:0006457;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chaperone#PC00072 CIOIN|Ensembl=ENSCING00000023973.1|UniProtKB=H2XKU9 H2XKU9 LOC100176581 PTHR11723:SF17 DNA-BINDING PROTEIN INHIBITOR PROTEIN EXTRA-MACROCHAETAE negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;rhythmic process#GO:0048511;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;regulation of biosynthetic process#GO:0009889;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;cellular developmental process#GO:0048869;circadian rhythm#GO:0007623;negative regulation of biosynthetic process#GO:0009890;regulation of DNA-templated transcription#GO:0006355;negative regulation of metabolic process#GO:0009892;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;circadian regulation of gene expression#GO:0032922;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218 CIOIN|Ensembl=ENSCING00000000938.3|UniProtKB=L7N0Q4 L7N0Q4 PTHR19325:SF567 COMPLEMENT COMPONENT-RELATED SUSHI DOMAIN-CONTAINING SUSHI, VON WILLEBRAND FACTOR TYPE A, EGF AND PENTRAXIN DOMAIN-CONTAINING PROTEIN 1-LIKE complement component#PC00078 CIOIN|Ensembl=ENSCING00000005756.3|UniProtKB=F6VN53 F6VN53 PTHR23082:SF0 TRANSCRIPTION INITIATION FACTOR IIIC TFIIIC , POLYPEPTIDE 3-RELATED GENERAL TRANSCRIPTION FACTOR 3C POLYPEPTIDE 3 cellular aromatic compound metabolic process#GO:0006725;DNA-templated transcription#GO:0006351;heterocycle metabolic process#GO:0046483;transcription by RNA polymerase III#GO:0006383;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;RNA biosynthetic process#GO:0032774;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;aromatic compound biosynthetic process#GO:0019438;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;transcription factor TFIIIC complex#GO:0000127 RNA metabolism protein#PC00031;general transcription factor#PC00259 CIOIN|Ensembl=ENSCING00000006503.3|UniProtKB=F6PW95 F6PW95 PTHR45636:SF41 PAIRED BOX PROTEIN PAX-6-RELATED-RELATED PAIRED BOX PROTEIN PAX-6-RELATED sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 homeodomain transcription factor#PC00119 CIOIN|Ensembl=ENSCING00000001172.3|UniProtKB=F6WAN9 F6WAN9 zf(phd)-1 PTHR24102:SF28 PHD FINGER PROTEIN PHD-TYPE DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000018769.1|UniProtKB=Q1RPU6 Q1RPU6 Ci-RP-2 PTHR11239:SF12 DNA-DIRECTED RNA POLYMERASE DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC10 catalytic activity, acting on RNA#GO:0140098;5'-3' RNA polymerase activity#GO:0034062;transferase activity#GO:0016740;DNA-directed 5'-3' RNA polymerase activity#GO:0003899;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;RNA polymerase activity#GO:0097747;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring phosphorus-containing groups#GO:0016772 RNA metabolism protein#PC00031;DNA-directed RNA polymerase#PC00019 CIOIN|Ensembl=ENSCING00000007033.3|UniProtKB=F6ZVY0 F6ZVY0 PTHR10896:SF65 GALACTOSYLGALACTOSYLXYLOSYLPROTEIN 3-BETA-GLUCURONOSYLTRANSFERASE BETA-1,3-GLUCURONYLTRANSFERASE GALACTOSYLGALACTOSYLXYLOSYLPROTEIN 3-BETA-GLUCURONOSYLTRANSFERASE 3 carbohydrate metabolic process#GO:0005975;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;primary metabolic process#GO:0044238 cytoplasm#GO:0005737;bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;Golgi membrane#GO:0000139;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111 CIOIN|Ensembl=ENSCING00000005383.3|UniProtKB=F7AVZ3 F7AVZ3 LOC100181891 PTHR11348:SF17 CONNECTIVE TISSUE GROWTH FACTOR-RELATED CCN carbohydrate derivative binding#GO:0097367;integrin binding#GO:0005178;binding#GO:0005488;heparin binding#GO:0008201;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;glycosaminoglycan binding#GO:0005539;signaling receptor binding#GO:0005102 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;positive regulation of cell differentiation#GO:0045597;cell communication#GO:0007154;cell adhesion#GO:0007155;cellular process#GO:0009987;regulation of cell differentiation#GO:0045595;positive regulation of developmental process#GO:0051094;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;biological regulation#GO:0065007;signaling#GO:0023052;positive regulation of biological process#GO:0048518 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;extracellular space#GO:0005615;extracellular region#GO:0005576 growth factor#PC00112 CIOIN|Ensembl=ENSCING00000006356.3|UniProtKB=F6PR01 F6PR01 PTHR12127:SF7 MUCOLIPIN SD02261P calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;calcium channel activity#GO:0005262;ligand-gated monoatomic ion channel activity#GO:0015276;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;ligand-gated monoatomic cation channel activity#GO:0099094;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;inorganic cation transmembrane transporter activity#GO:0022890;ligand-gated channel activity#GO:0022834 cellular anatomical entity#GO:0110165;membrane#GO:0016020 ion channel#PC00133;transporter#PC00227 CIOIN|Ensembl=ENSCING00000020237.1|UniProtKB=H2XVT8 H2XVT8 LOC100185070 PTHR28583:SF4 ACID AMIDASE N-ACYLETHANOLAMINE-HYDROLYZING ACID AMIDASE hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;catalytic activity#GO:0003824 cysteine protease#PC00081;protease#PC00190 CIOIN|Ensembl=ENSCING00000007754.3|UniProtKB=F6XU54 F6XU54 PTHR10161:SF14 TARTRATE-RESISTANT ACID PHOSPHATASE TYPE 5 TARTRATE-RESISTANT ACID PHOSPHATASE TYPE 5 hydrolase#PC00121;phosphatase#PC00181 CIOIN|Ensembl=ENSCING00000016079.2|UniProtKB=F6VJJ2 F6VJJ2 PTHR11690:SF286 AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED ACID-SENSING ION CHANNEL 5 monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;ligand-gated monoatomic cation channel activity#GO:0099094;sodium channel activity#GO:0005272;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;ligand-gated channel activity#GO:0022834 localization#GO:0051179;sodium ion transport#GO:0006814;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;monoatomic cation transport#GO:0006812;inorganic ion transmembrane transport#GO:0098660;monoatomic ion transport#GO:0006811;cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;sodium ion transmembrane transport#GO:0035725 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 CIOIN|Ensembl=ENSCING00000004901.3|UniProtKB=F7B9A3 F7B9A3 PTHR13132:SF29 ALPHA- 1,6 -FUCOSYLTRANSFERASE ALPHA-(1,6)-FUCOSYLTRANSFERASE transferase activity#GO:0016740;fucosyltransferase activity#GO:0008417;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein glycosylation#GO:0006486;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein N-linked glycosylation#GO:0006487;protein metabolic process#GO:0019538;glycosylation#GO:0070085;glycoprotein metabolic process#GO:0009100;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 glycosyltransferase#PC00111 Notch signaling pathway#P00045>Neurotic#P01115 CIOIN|Ensembl=ENSCING00000004793.3|UniProtKB=F6RF18 F6RF18 PTHR10574:SF274 NETRIN/LAMININ-RELATED USHERIN animal organ morphogenesis#GO:0009887;anatomical structure morphogenesis#GO:0009653;tissue development#GO:0009888;anatomical structure development#GO:0048856;animal organ development#GO:0048513;developmental process#GO:0032502 extracellular matrix protein#PC00102 CIOIN|Ensembl=ENSCING00000004817.3|UniProtKB=F6W2N4 F6W2N4 PTHR24347:SF370 SERINE/THREONINE-PROTEIN KINASE PERIPHERAL PLASMA MEMBRANE PROTEIN CASK transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;protein binding#GO:0005515;calmodulin binding#GO:0005516;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;neuron projection#GO:0043005;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000007536.3|UniProtKB=F6TVK0 F6TVK0 LOC100182216 PTHR23138:SF142 RAN BINDING PROTEIN RAN-BINDING PROTEIN 3B-RELATED scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000018861.1|UniProtKB=H2XRJ7 H2XRJ7 LOC101243272 PTHR45749:SF14 FAMILY NOT NAMED TTF-TYPE DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000007633.3|UniProtKB=F6XNK4 F6XNK4 PTHR16133:SF0 SOLUTE CARRIER FAMILY 39 ZINC TRANSPORTER , MEMBER 9-RELATED ZINC_IRON REGULATED TRANSPORTER-RELATED PROTEIN 102B, ISOFORM E secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000007312.3|UniProtKB=F6Z3I0 F6Z3I0 PTHR43016:SF13 PRESEQUENCE PROTEASE PRESEQUENCE PROTEASE, MITOCHONDRIAL metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000020094.1|UniProtKB=F7BQ10 F7BQ10 PTHR12963:SF0 THYROID RECEPTOR INTERACTING PROTEIN RELATED EXPRESSED PROTEIN transcription cofactor#PC00217 CIOIN|Ensembl=ENSCING00000025041.1|UniProtKB=F6TVK8 F6TVK8 PTHR44156:SF26 SUPERNUMERARY LIMBS, ISOFORM B-RELATED F-BOX AND WD REPEAT DOMAIN-CONTAINING 9-RELATED ubiquitin ligase-substrate adaptor activity#GO:1990756;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein polyubiquitination#GO:0000209;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 SCF ubiquitin ligase complex#GO:0019005;intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;cullin-RING ubiquitin ligase complex#GO:0031461;transferase complex#GO:1990234 Notch signaling pathway#P00045>Sel 10#P01102 CIOIN|Ensembl=ENSCING00000008843.3|UniProtKB=F6R4H2 F6R4H2 LOC100181821 PTHR24056:SF233 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE 9 cyclin-dependent protein kinase activity#GO:0097472;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;cyclin-dependent protein serine/threonine kinase activity#GO:0004693;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;phosphorylation#GO:0016310;protein phosphorylation#GO:0006468;cellular process#GO:0009987;protein metabolic process#GO:0019538;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 CIOIN|Ensembl=ENSCING00000012478.2|UniProtKB=F6U667 F6U667 PTHR24343:SF348 SERINE/THREONINE KINASE AT25266P transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;phosphorylation#GO:0016310;protein phosphorylation#GO:0006468;cellular process#GO:0009987;protein metabolic process#GO:0019538;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000022192.1|UniProtKB=H2XJK8 H2XJK8 LOC100184063 PTHR21397:SF2 CHROMATIN COMPLEXES SUBUNIT BAP18-RELATED CHROMATIN COMPLEXES SUBUNIT BAP18 membrane-enclosed lumen#GO:0031974;histone methyltransferase complex#GO:0035097;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-DNA complex#GO:0032993;chromatin#GO:0000785;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;transferase complex#GO:1990234;ATPase complex#GO:1904949;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;methyltransferase complex#GO:0034708;SWI/SNF superfamily-type complex#GO:0070603;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 chromatin/chromatin-binding, or -regulatory protein#PC00077 CIOIN|Ensembl=ENSCING00000001590.3|UniProtKB=Q1RL93 Q1RL93 Ci-ZF(FYVE)-7 PTHR45956:SF6 RUN AND FYVE DOMAIN-CONTAINING PROTEIN 2-LIKE PROTEIN RUN DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000006750.3|UniProtKB=F6Y0M4 F6Y0M4 LOC100180054 PTHR44163:SF1 U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 4 HOMOLOG U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 4 HOMOLOG nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;maturation of SSU-rRNA#GO:0030490;ribosomal small subunit biogenesis#GO:0042274;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;t-UTP complex#GO:0034455;small-subunit processome#GO:0032040;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;nuclear lumen#GO:0031981;90S preribosome#GO:0030686;nuclear protein-containing complex#GO:0140513 CIOIN|Ensembl=ENSCING00000021591.1|UniProtKB=H2XSW2 H2XSW2 PTHR34400:SF4 FAMILY NOT NAMED MEMBRANE PROTEIN CIOIN|Ensembl=ENSCING00000007054.3|UniProtKB=F6ZBV1 F6ZBV1 LOC100181403 PTHR19965:SF96 RNA AND EXPORT FACTOR BINDING PROTEIN POLYMERASE DELTA-INTERACTING PROTEIN 3 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 poly(A)+ mRNA export from nucleus#GO:0016973;mRNA export from nucleus#GO:0006406;cellular localization#GO:0051641;macromolecule biosynthetic process#GO:0009059;macromolecule localization#GO:0033036;establishment of RNA localization#GO:0051236;macromolecule metabolic process#GO:0043170;transport#GO:0006810;nucleic acid transport#GO:0050657;nitrogen compound transport#GO:0071705;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;mRNA transport#GO:0051028;RNA localization#GO:0006403;localization#GO:0051179;organic substance transport#GO:0071702;nuclear export#GO:0051168;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;RNA transport#GO:0050658;nucleobase-containing compound transport#GO:0015931;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;nuclear transport#GO:0051169;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;nuclear speck#GO:0016607;organelle#GO:0043226;nuclear body#GO:0016604;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000009695.3|UniProtKB=F6U6Q9 F6U6Q9 LOC100184022 PTHR13826:SF14 INTESTINAL TREFOIL FACTOR-RELATED TREFOIL FACTOR 2 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 CIOIN|Ensembl=ENSCING00000002588.3|UniProtKB=F6TRJ7 F6TRJ7 PTHR11849:SF282 ETS ETV5-RELATED PROTEIN ETS96B transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 CIOIN|Ensembl=ENSCING00000003286.3|UniProtKB=F6WN68 F6WN68 PTHR14465:SF0 IQ DOMAIN-CONTAINING PROTEIN H IQ DOMAIN-CONTAINING PROTEIN H CIOIN|Ensembl=ENSCING00000007221.3|UniProtKB=Q4H3I6 Q4H3I6 Ci-FoxI-a PTHR11829:SF384 FORKHEAD BOX PROTEIN FORK-HEAD DOMAIN-CONTAINING PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;anatomical structure morphogenesis#GO:0009653;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 CIOIN|Ensembl=ENSCING00000007823.3|UniProtKB=F6XFG7 F6XFG7 PTHR21468:SF1 HSD9 COILED-COIL DOMAIN-CONTAINING PROTEIN 83 CIOIN|Ensembl=ENSCING00000004194.3|UniProtKB=F7ALL8 F7ALL8 delta PTHR24044:SF488 NOTCH LIGAND FAMILY MEMBER NEUROGENIC LOCUS PROTEIN DELTA protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 intercellular signal molecule#PC00207 Notch signaling pathway#P00045>Delta#P01116;Angiogenesis#P00005>Delta/Serrate#P00226 CIOIN|Ensembl=ENSCING00000018380.1|UniProtKB=H2XYN4 H2XYN4 PTHR10404:SF74 N-ACETYLATED-ALPHA-LINKED ACIDIC DIPEPTIDASE AMINOPEPTIDASE NAALADL1-LIKE hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;carboxypeptidase activity#GO:0004180 metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000008194.3|UniProtKB=F6PJM3 F6PJM3 LOC100181071 PTHR13326:SF31 TRNA PSEUDOURIDINE SYNTHASE D PSEUDOURIDYLATE SYNTHASE 7 HOMOLOG isomerase activity#GO:0016853;intramolecular transferase activity#GO:0016866;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;RNA modification#GO:0009451;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;pseudouridine synthesis#GO:0001522;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000003596.3|UniProtKB=F6UYE6 F6UYE6 LOC100179627 PTHR10454:SF244 CASPASE CASPASE-6-LIKE cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197;hydrolase activity#GO:0016787;cysteine-type endopeptidase activity involved in apoptotic process#GO:0097153;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0043280;positive regulation of cysteine-type endopeptidase activity#GO:2001056;regulation of protein metabolic process#GO:0051246;regulation of cysteine-type endopeptidase activity#GO:2000116;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;positive regulation of proteolysis#GO:0045862;regulation of biological process#GO:0050789;activation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0006919;positive regulation of programmed cell death#GO:0043068;positive regulation of metabolic process#GO:0009893;regulation of molecular function#GO:0065009;apoptotic process#GO:0006915;cell death#GO:0008219;regulation of hydrolase activity#GO:0051336;positive regulation of peptidase activity#GO:0010952;positive regulation of biological process#GO:0048518;regulation of programmed cell death#GO:0043067;positive regulation of apoptotic process#GO:0043065;regulation of proteolysis#GO:0030162;regulation of apoptotic process#GO:0042981;positive regulation of catalytic activity#GO:0043085;programmed cell death#GO:0012501;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of hydrolase activity#GO:0051345;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;positive regulation of protein metabolic process#GO:0051247;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of endopeptidase activity#GO:0052548;regulation of peptidase activity#GO:0052547;regulation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0043281;positive regulation of endopeptidase activity#GO:0010950;regulation of metabolic process#GO:0019222 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 protease#PC00190;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000008919.3|UniProtKB=F6QAQ0 F6QAQ0 PTHR11129:SF2 PROTEIN FARNESYLTRANSFERASE ALPHA SUBUNIT/RAB GERANYLGERANYL TRANSFERASE ALPHA SUBUNIT GERANYLGERANYL TRANSFERASE TYPE-2 SUBUNIT ALPHA prenyltransferase activity#GO:0004659;transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein modification process#GO:0036211;cellular process#GO:0009987;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;transferase complex#GO:1990234 acyltransferase#PC00042;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000009062.3|UniProtKB=F6R255 F6R255 LOC100179078 PTHR11142:SF5 PSEUDOURIDYLATE SYNTHASE TRNA PSEUDOURIDINE(38_39) SYNTHASE isomerase activity#GO:0016853;intramolecular transferase activity#GO:0016866;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA modification#GO:0009451;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;mRNA modification#GO:0016556;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;tRNA modification#GO:0006400;primary metabolic process#GO:0044238;pseudouridine synthesis#GO:0001522;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 lyase#PC00144 CIOIN|Ensembl=ENSCING00000019304.1|UniProtKB=H2XZ90 H2XZ90 PTHR18849:SF0 LEUCINE RICH REPEAT PROTEIN CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 410-RELATED CIOIN|Ensembl=ENSCING00000012603.2|UniProtKB=F6XF25 F6XF25 PTHR31395:SF23 SHISA GEO05642P1 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000012822.2|UniProtKB=F6RLA4 F6RLA4 PTHR10201:SF331 MATRIX METALLOPROTEINASE MATRIX METALLOPROTEINASE-14-LIKE ISOFORM X1 hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular component organization or biogenesis#GO:0071840;extracellular structure organization#GO:0043062;external encapsulating structure organization#GO:0045229;catabolic process#GO:0009056;cellular component organization#GO:0016043;cellular process#GO:0009987;extracellular matrix organization#GO:0030198;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000014744|UniProtKB=Q1JV40 Q1JV40 HVCN1 PTHR46480:SF1 F20B24.22 VOLTAGE-GATED HYDROGEN CHANNEL 1 monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;voltage-gated channel activity#GO:0022832;proton channel activity#GO:0015252;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;transporter activity#GO:0005215;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;proton transmembrane transporter activity#GO:0015078;gated channel activity#GO:0022836;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;proton transmembrane transport#GO:1902600;monoatomic ion transmembrane transport#GO:0034220;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;monoatomic cation transport#GO:0006812;inorganic ion transmembrane transport#GO:0098660;monoatomic ion transport#GO:0006811;cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 CIOIN|Ensembl=ENSCING00000006409.3|UniProtKB=F6QSJ0 F6QSJ0 PTHR23294:SF0 ET TRANSLATION PRODUCT-RELATED UNC93-LIKE PROTEIN MFSD11 CIOIN|Ensembl=ENSCING00000004086.3|UniProtKB=Q1RLA5 Q1RLA5 Ci-ZF(C3H)-16 PTHR12620:SF8 U2 SNRNP AUXILIARY FACTOR, SMALL SUBUNIT U2 SMALL NUCLEAR RNA AUXILIARY FACTOR 1 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;pre-mRNA binding#GO:0036002;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA splicing factor#PC00148;RNA processing factor#PC00147;RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000012260.2|UniProtKB=F7ALF0 F7ALF0 LOC100186461 PTHR23064:SF72 TROPONIN TROPONIN C, SKELETAL MUSCLE cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 CIOIN|Ensembl=ENSCING00000004237.3|UniProtKB=F6YGD1 F6YGD1 PTHR12860:SF0 SIGNAL RECOGNITION PARTICLE 68 KDA PROTEIN SIGNAL RECOGNITION PARTICLE SUBUNIT SRP68 ribonucleoprotein complex binding#GO:0043021;protein-containing complex binding#GO:0044877;binding#GO:0005488 localization within membrane#GO:0051668;cotranslational protein targeting to membrane#GO:0006613;cellular localization#GO:0051641;protein localization to endoplasmic reticulum#GO:0070972;macromolecule localization#GO:0033036;protein localization to membrane#GO:0072657;protein targeting#GO:0006605;establishment of protein localization to organelle#GO:0072594;protein targeting to ER#GO:0045047;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;SRP-dependent cotranslational protein targeting to membrane#GO:0006614;localization#GO:0051179;establishment of protein localization to membrane#GO:0090150;protein targeting to membrane#GO:0006612;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein localization to organelle#GO:0033365;establishment of protein localization to endoplasmic reticulum#GO:0072599 cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000003242.3|UniProtKB=F6ZNS9 F6ZNS9 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE SSU-1 sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824 cellular metabolic process#GO:0044237;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000018855.1|UniProtKB=H2XYD5 H2XYD5 PTHR12888:SF0 PEROXISOME ASSEMBLY PROTEIN 12 PEROXIN-12 PEROXISOME ASSEMBLY PROTEIN 12 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824 cellular localization#GO:0051641;intracellular protein transmembrane transport#GO:0065002;macromolecule localization#GO:0033036;macromolecule modification#GO:0043412;protein import into peroxisome matrix#GO:0016558;transport#GO:0006810;protein transmembrane transport#GO:0071806;nitrogen compound transport#GO:0071705;protein modification process#GO:0036211;post-translational protein modification#GO:0043687;protein transmembrane import into intracellular organelle#GO:0044743;establishment of protein localization#GO:0045184;organic substance transport#GO:0071702;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;protein localization to organelle#GO:0033365;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;transmembrane transport#GO:0055085;macromolecule metabolic process#GO:0043170;protein monoubiquitination#GO:0006513;organonitrogen compound metabolic process#GO:1901564;establishment of protein localization to organelle#GO:0072594;cellular component organization#GO:0016043;cellular process#GO:0009987;protein localization#GO:0008104;primary metabolic process#GO:0044238;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;organelle organization#GO:0006996;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;peroxisome organization#GO:0007031 bounding membrane of organelle#GO:0098588;peroxisomal membrane#GO:0005778;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;transporter complex#GO:1990351;peroxisome#GO:0005777;membrane-bounded organelle#GO:0043227;microbody#GO:0042579;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chaperone#PC00072 CIOIN|Ensembl=ENSCING00000000752.3|UniProtKB=F6Q0S7 F6Q0S7 PTHR12695:SF2 GENERAL TRANSCRIPTION FACTOR IIH SUBUNIT 2 GENERAL TRANSCRIPTION FACTOR IIH SUBUNIT 2-RELATED DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleotide-excision repair#GO:0006289;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;regulation of DNA-templated transcription#GO:0006355;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;response to stress#GO:0006950;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;cellular response to stress#GO:0033554;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;DNA metabolic process#GO:0006259 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;DNA-directed RNA polymerase complex#GO:0000428;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nucleoplasm#GO:0005654;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;serine/threonine protein kinase complex#GO:1902554;RNA polymerase II transcription regulator complex#GO:0090575;protein kinase complex#GO:1902911;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622;RNA polymerase II, holoenzyme#GO:0016591;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;transcription regulator complex#GO:0005667;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;transcription factor TFIIH holo complex#GO:0005675;nuclear protein-containing complex#GO:0140513 general transcription factor#PC00259 CIOIN|Ensembl=ENSCING00000012808.2|UniProtKB=F6XZZ5 F6XZZ5 LOC101243196 PTHR46830:SF1 TRANSFERASE, PUTATIVE-RELATED ALPHA-1,4-N-ACETYLGLUCOSAMINYLTRANSFERASE transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000007794.3|UniProtKB=Q1RLF9 Q1RLF9 Ci-MYTF PTHR10816:SF15 MYELIN TRANSCRIPTION FACTOR 1-RELATED MYELIN TRANSCRIPTION FACTOR 1-LIKE PROTEIN zinc finger transcription factor#PC00244 CIOIN|Ensembl=ENSCING00000009184.3|UniProtKB=F6V8I4 F6V8I4 LOC100176457 PTHR23055:SF167 CALCIUM BINDING PROTEINS EF-HAND DOMAIN-CONTAINING PROTEIN cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488 calmodulin-related#PC00061 CIOIN|Ensembl=ENSCING00000024278.1|UniProtKB=H2Y005 H2Y005 PTHR23335:SF1 CALMODULIN-BINDING TRANSCRIPTION ACTIVATOR CAMTA CALMODULIN-BINDING TRANSCRIPTION ACTIVATOR, ISOFORM F molecular adaptor activity#GO:0060090;nucleic acid binding#GO:0003676;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;binding#GO:0005488;organic cyclic compound binding#GO:0097159;protein-macromolecule adaptor activity#GO:0030674;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218 CIOIN|Ensembl=ENSCING00000004762.3|UniProtKB=F6PMJ8 F6PMJ8 LOC100186332 PTHR12002:SF116 CLAUDIN CLAUDIN-11-LIKE cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cell-cell junction organization#GO:0045216;cellular component biogenesis#GO:0044085;cell-cell junction assembly#GO:0007043;cell junction organization#GO:0034330;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;cell adhesion#GO:0007155;cellular process#GO:0009987 tight junction#GO:0070160;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cell junction#GO:0030054;bicellular tight junction#GO:0005923;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;apical junction complex#GO:0043296;plasma membrane#GO:0005886 cell junction protein#PC00070;tight junction#PC00214 CIOIN|Ensembl=ENSCING00000006274.3|UniProtKB=F6V259 F6V259 PTHR22802:SF456 C-TYPE LECTIN SUPERFAMILY MEMBER FI01427P membrane traffic protein#PC00150 CIOIN|Ensembl=ENSCING00000024730.1|UniProtKB=H2XXE6 H2XXE6 LOC100182050 PTHR21324:SF18 FASTING-INDUCIBLE INTEGRAL MEMBRANE PROTEIN TM6P1-RELATED DNA DAMAGE-REGULATED AUTOPHAGY MODULATOR PROTEIN 1-LIKE scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000000431.3|UniProtKB=F7BKP7 F7BKP7 PTHR24372:SF77 GLYCOPROTEIN HORMONE RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 response to organic substance#GO:0010033;positive regulation of adenylate cyclase activity#GO:0045762;regulation of lyase activity#GO:0051339;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;cellular response to stimulus#GO:0051716;regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;cellular response to endogenous stimulus#GO:0071495;cellular response to chemical stimulus#GO:0070887;positive regulation of catalytic activity#GO:0043085;cellular response to organic substance#GO:0071310;regulation of cyclase activity#GO:0031279;positive regulation of molecular function#GO:0044093;cell communication#GO:0007154;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;positive regulation of cyclase activity#GO:0031281;hormone-mediated signaling pathway#GO:0009755;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to endogenous stimulus#GO:0009719;response to hormone#GO:0009725;cellular response to hormone stimulus#GO:0032870;response to chemical#GO:0042221;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of lyase activity#GO:0051349;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 CIOIN|Ensembl=ENSCING00000002709.3|UniProtKB=F6UE02 F6UE02 LOC100181928 PTHR11246:SF3 PRE-MRNA SPLICING FACTOR CROOKED NECK-LIKE PROTEIN 1 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;RNA processing#GO:0006396;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;protein-RNA complex assembly#GO:0022618;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;mRNA splicing, via spliceosome#GO:0000398;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;protein-containing complex organization#GO:0043933;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;ribonucleoprotein complex biogenesis#GO:0022613;mRNA processing#GO:0006397;protein-RNA complex organization#GO:0071826;RNA splicing, via transesterification reactions#GO:0000375;spliceosomal complex assembly#GO:0000245 catalytic step 2 spliceosome#GO:0071013;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;U2-type spliceosomal complex#GO:0005684;cellular anatomical entity#GO:0110165;organelle#GO:0043226;post-mRNA release spliceosomal complex#GO:0071014;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;precatalytic spliceosome#GO:0071011;membrane-bounded organelle#GO:0043227;Prp19 complex#GO:0000974;nuclear protein-containing complex#GO:0140513 RNA splicing factor#PC00148;RNA processing factor#PC00147 CIOIN|Ensembl=ENSCING00000007083.3|UniProtKB=F6W9J4 F6W9J4 PTHR11596:SF94 ALKALINE PHOSPHATASE ALKALINE PHOSPHATASE hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 cellular metabolic process#GO:0044237;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;dephosphorylation#GO:0016311;metabolic process#GO:0008152 phosphatase#PC00181;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000002157.3|UniProtKB=Q8IAC7 Q8IAC7 Ci-En PTHR24341:SF6 HOMEOBOX PROTEIN ENGRAILED HOMEOBOX PROTEIN INVECTED homeodomain transcription factor#PC00119 Wnt signaling pathway#P00057>Wnt Target Genes#G01558 CIOIN|Ensembl=ENSCING00000022674.1|UniProtKB=H2XZL5 H2XZL5 PTHR11258:SF22 2-5 OLIGOADENYLATE SYNTHETASE MATH DOMAIN-CONTAINING PROTEIN adenylyltransferase activity#GO:0070566;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;transferase activity#GO:0016740;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;nucleotidyltransferase activity#GO:0016779;transferase activity, transferring phosphorus-containing groups#GO:0016772;double-stranded RNA binding#GO:0003725 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule metabolic process#GO:0060255;regulation of molecular function#GO:0065009;regulation of nitrogen compound metabolic process#GO:0051171;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of hydrolase activity#GO:0051336;regulation of catalytic activity#GO:0050790;regulation of RNA metabolic process#GO:0051252;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 nucleotidyltransferase#PC00174 CIOIN|Ensembl=ENSCING00000014068.2|UniProtKB=F6UVY1 F6UVY1 LOC100180010 PTHR10334:SF590 CYSTEINE-RICH SECRETORY PROTEIN-RELATED SCP DOMAIN-CONTAINING PROTEIN extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 defense/immunity protein#PC00090 CIOIN|Ensembl=ENSCING00000006326.3|UniProtKB=F6Q3M5 F6Q3M5 LOC100187037 PTHR24114:SF50 LEUCINE RICH REPEAT FAMILY PROTEIN RNI-LIKE PROTEIN CIOIN|Ensembl=ENSCING00000007297.3|UniProtKB=F6S7I2 F6S7I2 PTHR44099:SF4 RABCONNECTIN-3B, ISOFORM A RABCONNECTIN-3B, ISOFORM A cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000021198.1|UniProtKB=H2XK90 H2XK90 PTHR46473:SF23 GH08155P GH08155P CIOIN|Ensembl=ENSCING00000002960.3|UniProtKB=F6R3W0 F6R3W0 LOC100178081 PTHR24073:SF352 DRAB5-RELATED RAS-RELATED PROTEIN RAB6 GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824 endosomal transport#GO:0016197;cellular localization#GO:0051641;intra-Golgi vesicle-mediated transport#GO:0006891;macromolecule localization#GO:0033036;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;cytosolic transport#GO:0016482;establishment of protein localization#GO:0045184;retrograde transport, endosome to Golgi#GO:0042147;protein localization#GO:0008104;localization#GO:0051179;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 small GTPase#PC00208;G-protein#PC00020 CIOIN|Ensembl=ENSCING00000004917.3|UniProtKB=F7AQG9 F7AQG9 PTHR24115:SF0 KINESIN-RELATED FI21273P1-RELATED pyrophosphatase activity#GO:0016462;cytoskeletal protein binding#GO:0008092;microtubule motor activity#GO:0003777;tubulin binding#GO:0015631;ATP-dependent activity#GO:0140657;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;cytoskeletal motor activity#GO:0003774;microtubule binding#GO:0008017;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;ribonucleoside triphosphate phosphatase activity#GO:0017111;ATP hydrolysis activity#GO:0016887 microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017;cellular process#GO:0009987 supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;cytoskeleton#GO:0005856;microtubule#GO:0005874;spindle#GO:0005819 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 CIOIN|Ensembl=ENSCING00000004226.3|UniProtKB=F6YGJ7 F6YGJ7 PTHR24006:SF644 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 7 cysteine-type peptidase activity#GO:0008234;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;cysteine-type deubiquitinase activity#GO:0004843 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;regulation of protein stability#GO:0031647;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;protein modification by small protein removal#GO:0070646;protein deubiquitination#GO:0016579;biological regulation#GO:0065007;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cysteine protease#PC00081;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000023665.1|UniProtKB=H2Y037 H2Y037 PTHR24383:SF20 ZINC FINGER PROTEIN C2H2-TYPE DOMAIN-CONTAINING PROTEIN C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 CIOIN|Ensembl=ENSCING00000022129.1|UniProtKB=H2XQD2 H2XQD2 PTHR10174:SF225 ALPHA-TOCOPHEROL TRANSFER PROTEIN-RELATED ALPHA-TOCOPHEROL TRANSFER PROTEIN phosphatidylinositol bisphosphate binding#GO:1902936;lipid binding#GO:0008289;phosphatidylinositol binding#GO:0035091;phospholipid binding#GO:0005543;phosphatidylinositol phosphate binding#GO:1901981;binding#GO:0005488 cellular anatomical entity#GO:0110165;membrane#GO:0016020 transfer/carrier protein#PC00219 CIOIN|Ensembl=ENSCING00000004457.3|UniProtKB=F6US09 F6US09 PTHR10749:SF7 PHOSPHORYLASE B KINASE REGULATORY SUBUNIT PHOSPHORYLASE B KINASE REGULATORY SUBUNIT ALPHA-RELATED cytoplasm#GO:0005737;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;transferase complex#GO:1990234;serine/threonine protein kinase complex#GO:1902554;protein kinase complex#GO:1902911;cellular anatomical entity#GO:0110165;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622 kinase modulator#PC00140;kinase activator#PC00138 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Phosphorylase b kinase#P00716 CIOIN|Ensembl=ENSCING00000001550.3|UniProtKB=A0A1W3JFQ5 A0A1W3JFQ5 LOC100177403 PTHR47456:SF1 PHD-TYPE DOMAIN-CONTAINING PROTEIN PHD-TYPE DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000019889.1|UniProtKB=H2Y2Z2 H2Y2Z2 PTHR10127:SF780 DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING METALLOENDOPEPTIDASE hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000002166.3|UniProtKB=F6SST4 F6SST4 LOC100183973 PTHR19359:SF150 CYTOCHROME B5 CYTOCHROME B5 tetrapyrrole binding#GO:0046906;binding#GO:0005488;organic cyclic compound binding#GO:0097159;heme binding#GO:0020037 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;membrane#GO:0016020;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000001648.3|UniProtKB=F6YJ84 F6YJ84 MED17 PTHR13114:SF7 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 17 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 17 molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;protein-macromolecule adaptor activity#GO:0030674 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;core mediator complex#GO:0070847;RNA polymerase II transcription regulator complex#GO:0090575;mediator complex#GO:0016592;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031;general transcription factor#PC00259 CIOIN|Ensembl=ENSCING00000005852.3|UniProtKB=F6V6I7 F6V6I7 PTHR24033:SF232 EGF-LIKE DOMAIN-CONTAINING PROTEIN LAMININ SUBUNIT GAMMA-2-RELATED Notch signaling pathway#P00045>Notch#P01099;Integrin signalling pathway#P00034>Laminin#P00947;Notch signaling pathway#P00045>NIct#P01119;Notch signaling pathway#P00045>NIcs#P01120;Notch signaling pathway#P00045>Ntm#P01114 CIOIN|Ensembl=ENSCING00000016374.2|UniProtKB=F6SRW6 F6SRW6 PTHR43539:SF23 FLAVIN-BINDING MONOOXYGENASE-LIKE PROTEIN (AFU_ORTHOLOGUE AFUA_4G09220) FAD-DEPENDENT OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN 2 nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;flavin adenine dinucleotide binding#GO:0050660;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;anion binding#GO:0043168;oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497 response to organic substance#GO:0010033;macromolecule catabolic process#GO:0009057;cellular response to stimulus#GO:0051716;response to endoplasmic reticulum stress#GO:0034976;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;response to organonitrogen compound#GO:0010243;ERAD pathway#GO:0036503;cellular process#GO:0009987;primary metabolic process#GO:0044238;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;cellular response to stress#GO:0033554;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;endoplasmic reticulum lumen#GO:0005788;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 oxygenase#PC00177;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000008824.3|UniProtKB=F6UE95 F6UE95 LOC100175475 PTHR23277:SF108 NECTIN-RELATED FASCICLIN-3 cell-cell adhesion via plasma-membrane adhesion molecules#GO:0098742;heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules#GO:0007157;cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987;homophilic cell adhesion via plasma membrane adhesion molecules#GO:0007156 cell junction#GO:0030054;adherens junction#GO:0005912;cellular anatomical entity#GO:0110165;cell-cell junction#GO:0005911;anchoring junction#GO:0070161 cell adhesion molecule#PC00069 CIOIN|Ensembl=ENSCING00000024265.1|UniProtKB=H2XVV1 H2XVV1 LOC100187030 PTHR15336:SF0 UBIQUINOL-CYTOCHROME C REDUCTASE COMPLEX 7.8 KDA PROTEIN CYTOCHROME B-C1 COMPLEX SUBUNIT 6, MITOCHONDRIAL mitochondrial ATP synthesis coupled electron transport#GO:0042775;aerobic respiration#GO:0009060;cellular respiration#GO:0045333;respiratory electron transport chain#GO:0022904;aerobic electron transport chain#GO:0019646;oxidative phosphorylation#GO:0006119;generation of precursor metabolites and energy#GO:0006091;electron transport chain#GO:0022900;ATP synthesis coupled electron transport#GO:0042773;cellular metabolic process#GO:0044237;mitochondrial electron transport, ubiquinol to cytochrome c#GO:0006122;cellular process#GO:0009987;energy derivation by oxidation of organic compounds#GO:0015980;metabolic process#GO:0008152 envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;cytochrome complex#GO:0070069;respiratory chain complex#GO:0098803;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transporter complex#GO:1990351;oxidoreductase complex#GO:1990204;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;respirasome#GO:0070469;protein-containing complex#GO:0032991;mitochondrial envelope#GO:0005740;mitochondrial respirasome#GO:0005746;transmembrane transporter complex#GO:1902495;inner mitochondrial membrane protein complex#GO:0098800;mitochondrial respiratory chain complex III#GO:0005750;membrane-bounded organelle#GO:0043227;mitochondrial protein-containing complex#GO:0098798 reductase#PC00198;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000021276.1|UniProtKB=H2XSI8 H2XSI8 LOC100180841 PTHR16105:SF0 RNA-BINDING REGION-CONTAINING PROTEIN 3 RNA-BINDING REGION-CONTAINING PROTEIN 3 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;snRNA binding#GO:0017069;pre-mRNA binding#GO:0036002;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;U12-type spliceosomal complex#GO:0005689 CIOIN|Ensembl=ENSCING00000002145.3|UniProtKB=Q4H308 Q4H308 Ci-Orphan Wnt b PTHR12027:SF37 WNT RELATED PROTEIN WNT molecular function activator activity#GO:0140677;binding#GO:0005488;molecular function regulator activity#GO:0098772;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;cytokine activity#GO:0005125;G protein-coupled receptor binding#GO:0001664;signaling receptor binding#GO:0005102 cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;neurogenesis#GO:0022008;developmental process#GO:0032502;multicellular organism development#GO:0007275;cell communication#GO:0007154;cell fate commitment#GO:0045165;cell-cell signaling by wnt#GO:0198738;nervous system development#GO:0007399;cellular process#GO:0009987;regulation of biological process#GO:0050789;system development#GO:0048731;response to stimulus#GO:0050896;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;neuron differentiation#GO:0030182;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;cell-cell signaling#GO:0007267;signaling#GO:0023052;canonical Wnt signaling pathway#GO:0060070;Wnt signaling pathway#GO:0016055 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 intercellular signal molecule#PC00207 CIOIN|Ensembl=ENSCING00000008555.3|UniProtKB=F6XP62 F6XP62 PTHR45027:SF1 PUTATIVE GLUTATHIONE HYDROLASE LIGHT CHAIN SUBFAMILY NOT NAMED metabolite interconversion enzyme#PC00262;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000004832.3|UniProtKB=F6YX18 F6YX18 PTHR24286:SF384 CYTOCHROME P450 26 P450, PUTATIVE (EUROFUNG)-RELATED oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497 sterol metabolic process#GO:0016125;organic hydroxy compound metabolic process#GO:1901615;lipid metabolic process#GO:0006629;steroid metabolic process#GO:0008202;organic cyclic compound metabolic process#GO:1901360;metabolic process#GO:0008152;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704 oxygenase#PC00177;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000019137.1|UniProtKB=H2XPA6 H2XPA6 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE SSU-1 sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824 cellular metabolic process#GO:0044237;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000013461.2|UniProtKB=F6UEA0 F6UEA0 PTHR42683:SF87 ALDEHYDE REDUCTASE ALCOHOL DEHYDROGENASE-LIKE ISOFORM X1 oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 organic hydroxy compound metabolic process#GO:1901615;alcohol metabolic process#GO:0006066;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000015785.2|UniProtKB=F7AHD2 F7AHD2 PTHR11571:SF222 GLUTATHIONE S-TRANSFERASE GLUTATHIONE TRANSFERASE glutathione transferase activity#GO:0004364;transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824 sulfur compound metabolic process#GO:0006790;nitrogen compound metabolic process#GO:0006807;peptide metabolic process#GO:0006518;cellular modified amino acid metabolic process#GO:0006575;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular process#GO:0009987;glutathione metabolic process#GO:0006749;amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000020898.1|UniProtKB=H2XNQ0 H2XNQ0 PTHR44324:SF6 WD40 REPEAT DOMAIN 95 EF-HAND CALCIUM BINDING DOMAIN 8 CIOIN|Ensembl=ENSCING00000014796.2|UniProtKB=F6VLB7 F6VLB7 LOC100176864 PTHR46466:SF1 GLYOXALASE DOMAIN-CONTAINING PROTEIN 4 GLYOXALASE DOMAIN-CONTAINING PROTEIN 4 CIOIN|Ensembl=ENSCING00000024977.1|UniProtKB=H2XX82 H2XX82 PTHR14453:SF67 PARP/ZINC FINGER CCCH TYPE DOMAIN CONTAINING PROTEIN POLY [ADP-RIBOSE] POLYMERASE molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714;protein-macromolecule adaptor activity#GO:0030674 negative regulation of gene expression#GO:0010629;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of biosynthetic process#GO:0009890;negative regulation of metabolic process#GO:0009892;regulation of biological process#GO:0050789;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000018561.1|UniProtKB=H2XNE6 H2XNE6 PTHR43248:SF3 2-SUCCINYL-6-HYDROXY-2,4-CYCLOHEXADIENE-1-CARBOXYLATE SYNTHASE AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN metabolite interconversion enzyme#PC00262;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000022043.1|UniProtKB=H2XVX7 H2XVX7 PTHR44329:SF291 SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED PROTEIN KINASE DOMAIN-CONTAINING PROTEIN MAP kinase kinase kinase activity#GO:0004709;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000004228.3|UniProtKB=F6YGJ1 F6YGJ1 PTHR10953:SF9 UBIQUITIN-ACTIVATING ENZYME E1 UBIQUITIN-LIKE MODIFIER-ACTIVATING ENZYME 5 ligase activity#GO:0016874;transferase activity#GO:0016740;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877;nucleotidyltransferase activity#GO:0016779;thiosulfate sulfurtransferase activity#GO:0004792;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity, acting on a protein#GO:0140096;sulfurtransferase activity#GO:0016783 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000008350.3|UniProtKB=F7B3P4 F7B3P4 PTHR10621:SF0 UV EXCISION REPAIR PROTEIN RAD23 UV EXCISION REPAIR PROTEIN RAD23 proteasome binding#GO:0070628;ubiquitin-like protein binding#GO:0032182;binding#GO:0005488;ubiquitin binding#GO:0043130;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;modification-dependent protein binding#GO:0140030;polyubiquitin modification-dependent protein binding#GO:0031593 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 damaged DNA-binding protein#PC00086;DNA metabolism protein#PC00009 CIOIN|Ensembl=ENSCING00000019091.1|UniProtKB=H2Y146 H2Y146 PTHR28589:SF1 28S RIBOSOMAL PROTEIN S34, MITOCHONDRIAL SMALL RIBOSOMAL SUBUNIT PROTEIN MS34 ribosomal protein#PC00202;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000008903.3|UniProtKB=F6QBI4 F6QBI4 snail PTHR24393:SF71 ZINC FINGER PROTEIN PR DOMAIN ZINC FINGER PROTEIN 15 DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 CIOIN|Ensembl=ENSCING00000022035.1|UniProtKB=H2XVP4 H2XVP4 PTHR13856:SF137 VHS DOMAIN CONTAINING PROTEIN FAMILY GH05942P protein binding#GO:0005515;clathrin binding#GO:0030276;binding#GO:0005488 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cytoplasm#GO:0005737;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000006482.3|UniProtKB=F6Q0W6 F6Q0W6 PTHR11062:SF129 EXOSTOSIN HEPARAN SULFATE GLYCOSYLTRANSFERASE -RELATED EXOSTOSIN-1 acetylglucosaminyltransferase activity#GO:0008375;glucuronosyltransferase activity#GO:0015020;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194;hexosyltransferase activity#GO:0016758 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111 CIOIN|Ensembl=ENSCING00000007881.3|UniProtKB=F6TGK6 F6TGK6 LOC113474389 PTHR45922:SF1 CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 2 CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 2 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;RNA processing#GO:0006396;mRNA polyadenylation#GO:0006378;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;mRNA 3'-end processing#GO:0031124;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;mRNA processing#GO:0006397;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;mRNA cleavage factor complex#GO:0005849;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;mRNA cleavage and polyadenylation specificity factor complex#GO:0005847;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000010128.3|UniProtKB=F6PIB9 F6PIB9 PTHR36978:SF4 P-LOOP CONTAINING NUCLEOTIDE TRIPHOSPHATE HYDROLASE P-LOOP CONTAINING NUCLEOSIDE TRIPHOSPHATE HYDROLASE PROTEIN metabolite interconversion enzyme#PC00262;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000002765.3|UniProtKB=F7AHE5 F7AHE5 PTHR23123:SF21 PHD/F-BOX CONTAINING PROTEIN JMJC DOMAIN-CONTAINING HISTONE DEMETHYLATION PROTEIN 1 histone modifying activity#GO:0140993;molecular adaptor activity#GO:0060090;demethylase activity#GO:0032451;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;histone demethylase activity#GO:0032452;catalytic activity#GO:0003824;protein-macromolecule adaptor activity#GO:0030674;catalytic activity, acting on a protein#GO:0140096 macromolecule modification#GO:0043412;regulation of DNA-templated transcription#GO:0006355;macromolecule metabolic process#GO:0043170;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;nitrogen compound metabolic process#GO:0006807;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 chromatin/chromatin-binding, or -regulatory protein#PC00077;histone modifying enzyme#PC00261 CIOIN|Ensembl=ENSCING00000021584.1|UniProtKB=H2XTD7 H2XTD7 LOC100184158 PTHR15071:SF34 MANNOSE-6-PHOSPHATE RECEPTOR FAMILY MEMBER MRH DOMAIN-CONTAINING PROTEIN cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;Golgi apparatus subcompartment#GO:0098791;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150 CIOIN|Ensembl=ENSCING00000024735.1|UniProtKB=H2XPU7 H2XPU7 LOC100181219 PTHR23320:SF162 MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MS4A -RELATED EXPRESSED PROTEIN transporter#PC00227 CIOIN|Ensembl=ENSCING00000022115.1|UniProtKB=H2XZM7 H2XZM7 LOC100187298 PTHR31781:SF1 UNC80 PROTEIN UNC-80 HOMOLOG monoatomic cation channel activity#GO:0005261;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;monoatomic ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267;monoatomic ion channel activity#GO:0005216;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215 monoatomic cation homeostasis#GO:0055080;homeostatic process#GO:0042592;chemical homeostasis#GO:0048878;monoatomic ion homeostasis#GO:0050801 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;neuron projection#GO:0043005;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;cation channel complex#GO:0034703;axon#GO:0030424 CIOIN|Ensembl=ENSCING00000018423.1|UniProtKB=H2XM87 H2XM87 PTHR15034:SF5 DEATH DOMAIN-CONTAINING PROTEIN CRADD DEATH DOMAIN-CONTAINING PROTEIN CRADD Wnt signaling pathway#P00057>Frizzled#P01428;Apoptosis signaling pathway#P00006>RAIDD#P00294;Cadherin signaling pathway#P00012>Frizzled#P00475;Alzheimer disease-presenilin pathway#P00004>Frizzled#P00119 CIOIN|Ensembl=ENSCING00000011563.2|UniProtKB=F6TBF1 F6TBF1 PTHR13349:SF2 TRANSLATION MACHINERY-ASSOCIATED PROTEIN 16 TRANSLATION MACHINERY-ASSOCIATED PROTEIN 16 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000019375.1|UniProtKB=H2XTD8 H2XTD8 PTHR13113:SF1 ECSIT EVOLUTIONARILY CONSERVED SIGNALING INTERMEDIATE IN TOLL PATHWAYS EVOLUTIONARILY CONSERVED SIGNALING INTERMEDIATE IN TOLL PATHWAY, MITOCHONDRIAL response to external biotic stimulus#GO:0043207;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;immune response#GO:0006955;cell communication#GO:0007154;cellular process#GO:0009987;defense response to symbiont#GO:0140546;regulation of biological process#GO:0050789;immune system process#GO:0002376;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;enzyme-linked receptor protein signaling pathway#GO:0007167;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological process involved in interspecies interaction between organisms#GO:0044419;biological regulation#GO:0065007;innate immune response#GO:0045087;defense response#GO:0006952;signaling#GO:0023052 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 Toll receptor signaling pathway#P00054>ECSIT#P01349 CIOIN|Ensembl=ENSCING00000018272.1|UniProtKB=H2XP90 H2XP90 KYNU PTHR14084:SF0 KYNURENINASE KYNURENINASE hydrolase activity#GO:0016787;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;heterocycle catabolic process#GO:0046700;biogenic amine metabolic process#GO:0006576;organonitrogen compound catabolic process#GO:1901565;cellular nitrogen compound catabolic process#GO:0044270;amino acid catabolic process#GO:0009063;organic cyclic compound metabolic process#GO:1901360;aromatic amino acid metabolic process#GO:0009072;nitrogen compound metabolic process#GO:0006807;alpha-amino acid metabolic process#GO:1901605;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248;heterocycle metabolic process#GO:0046483;amine metabolic process#GO:0009308;oxoacid metabolic process#GO:0043436;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;aromatic compound catabolic process#GO:0019439;organic cyclic compound catabolic process#GO:1901361;aromatic amino acid family catabolic process#GO:0009074;carboxylic acid metabolic process#GO:0019752;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000023936.1|UniProtKB=H2Y2I5 H2Y2I5 LOC100177134 PTHR31395:SF23 SHISA GEO05642P1 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000022915.1|UniProtKB=H2XRU5 H2XRU5 LOC100175224 PTHR24067:SF254 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2-17 KDA ubiquitin-like protein conjugating enzyme activity#GO:0061650;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin conjugating enzyme activity#GO:0061631;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;macromolecule modification#GO:0043412;protein catabolic process#GO:0030163;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;post-translational protein modification#GO:0043687;nucleobase-containing compound metabolic process#GO:0006139;modification-dependent macromolecule catabolic process#GO:0043632;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;protein polyubiquitination#GO:0000209;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;cellular response to stimulus#GO:0051716;protein ubiquitination#GO:0016567;modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 Ubiquitin proteasome pathway#P00060>E2#P01491 CIOIN|Ensembl=ENSCING00000022278.1|UniProtKB=H2Y2I0 H2Y2I0 PTHR47266:SF9 ENDONUCLEASE-RELATED INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000001461.3|UniProtKB=F6VJS2 F6VJS2 PTHR11824:SF5 VOLTAGE-DEPENDENT CALCIUM CHANNEL BETA SUBUNIT CA2+-CHANNEL-PROTEIN-BETA-SUBUNIT, ISOFORM L calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;calcium channel activity#GO:0005262;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;transporter activity#GO:0005215;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated calcium channel activity#GO:0005245;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 regulation of monoatomic ion transmembrane transport#GO:0034765;regulation of transmembrane transport#GO:0034762;regulation of metal ion transport#GO:0010959;trans-synaptic signaling#GO:0099537;regulation of calcium ion transport#GO:0051924;regulation of localization#GO:0032879;regulation of monoatomic cation transmembrane transport#GO:1904062;cellular component organization#GO:0016043;cell communication#GO:0007154;cellular process#GO:0009987;neuromuscular junction development#GO:0007528;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;synapse organization#GO:0050808;regulation of transport#GO:0051049;chemical synaptic transmission#GO:0007268;anterograde trans-synaptic signaling#GO:0098916;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;cell junction organization#GO:0034330;biological regulation#GO:0065007;synaptic signaling#GO:0099536;regulation of monoatomic ion transmembrane transporter activity#GO:0032412;regulation of monoatomic ion transport#GO:0043269;regulation of transmembrane transporter activity#GO:0022898;regulation of transporter activity#GO:0032409;cell-cell signaling#GO:0007267;signaling#GO:0023052 voltage-gated calcium channel complex#GO:0005891;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;calcium channel complex#GO:0034704;membrane#GO:0016020;cation channel complex#GO:0034703;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227;voltage-gated ion channel#PC00241 Thyrotropin-releasing hormone receptor signaling pathway#P04394>Ca2+ channel#P04587 CIOIN|Ensembl=ENSCING00000011402.2|UniProtKB=F6SXV5 F6SXV5 PTHR11559:SF424 CARBOXYLESTERASE CARBOXYLESTERASE 1D-LIKE ISOFORM X1 esterase#PC00097;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000006850.3|UniProtKB=F7AFJ0 F7AFJ0 PTHR24028:SF328 CADHERIN-87A CADHERIN-3 cell adhesion#GO:0007155;cellular process#GO:0009987 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cell adhesion molecule#PC00069;cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 CIOIN|Ensembl=ENSCING00000018649.1|UniProtKB=H2XJP3 H2XJP3 PTHR12483:SF115 SOLUTE CARRIER FAMILY 31 COPPER TRANSPORTERS COPPER TRANSPORT PROTEIN secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000021536.1|UniProtKB=H2XZ61 H2XZ61 LOC100175852 PTHR23320:SF165 MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MS4A -RELATED MARVEL DOMAIN-CONTAINING PROTEIN transporter#PC00227 CIOIN|Ensembl=ENSCING00000009054.3|UniProtKB=F6R2I4 F6R2I4 PTHR11474:SF126 TYROSINASE FAMILY MEMBER TYROSINASE-LIKE PROTEIN TYR-1-RELATED oxygenase#PC00177;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000021768.1|UniProtKB=H2XTA6 H2XTA6 PTHR20883:SF14 PHYTANOYL-COA DIOXYGENASE DOMAIN CONTAINING 1 PHYTANOYL-COA DIOXYGENASE oxygenase#PC00177;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000008120.3|UniProtKB=F6YM78 F6YM78 LOC100182691 PTHR45662:SF2 PHOSPHATIDYLINOSITIDE PHOSPHATASE SAC1 PHOSPHATIDYLINOSITOL-3-PHOSPHATASE SAC1 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 phospholipid dephosphorylation#GO:0046839;lipid metabolic process#GO:0006629;phosphatidylinositol dephosphorylation#GO:0046856;cellular metabolic process#GO:0044237;phosphatidylinositol metabolic process#GO:0046488;glycerophospholipid metabolic process#GO:0006650;lipid modification#GO:0030258;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;dephosphorylation#GO:0016311;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 phosphatase#PC00181;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000022351.1|UniProtKB=H2XS31 H2XS31 LOC100185310 PTHR21008:SF0 S-ADENOSYLMETHIONINE SENSOR UPSTREAM OF MTORC1-RELATED S-ADENOSYLMETHIONINE SENSOR UPSTREAM OF MTORC1 regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;regulation of TORC1 signaling#GO:1903432;negative regulation of response to stimulus#GO:0048585;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;negative regulation of TOR signaling#GO:0032007;regulation of intracellular signal transduction#GO:1902531;regulation of TOR signaling#GO:0032006;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of TORC1 signaling#GO:1904262;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648 CIOIN|Ensembl=ENSCING00000000624.3|UniProtKB=F6RRF2 F6RRF2 PTHR10540:SF8 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT F-RELATED COP9 SIGNALOSOME COMPLEX SUBUNIT 6 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;COP9 signalosome#GO:0008180;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622 translation initiation factor#PC00224;translation factor#PC00223 CIOIN|Ensembl=ENSCING00000000917.3|UniProtKB=Q6IMM2 Q6IMM2 RBJ PTHR24073:SF269 DRAB5-RELATED DNAJ HOMOLOG SUBFAMILY C MEMBER 27 GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824 localization#GO:0051179;organic substance transport#GO:0071702;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;transport#GO:0006810;protein transport#GO:0015031;nitrogen compound transport#GO:0071705;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104 cellular anatomical entity#GO:0110165;endomembrane system#GO:0012505 small GTPase#PC00208;G-protein#PC00020 Integrin signalling pathway#P00034>Rap1#P00906;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Rap1#P00734 CIOIN|Ensembl=ENSCING00000000295.3|UniProtKB=F6ZGR3 F6ZGR3 PTHR45702:SF6 ADAM10/ADAM17 METALLOPEPTIDASE FAMILY MEMBER DISINTEGRIN AND METALLOPROTEINASE DOMAIN-CONTAINING PROTEIN 17 hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;membrane protein proteolysis#GO:0033619;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cell communication#GO:0007154;cellular process#GO:0009987;membrane protein ectodomain proteolysis#GO:0006509;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;nitrogen compound metabolic process#GO:0006807;cell surface receptor signaling pathway#GO:0007166;proteolysis#GO:0006508;biological regulation#GO:0065007;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;Notch signaling pathway#GO:0007219 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 protease#PC00190;protein modifying enzyme#PC00260 Alzheimer disease-amyloid secretase pathway#P00003>TACE#P00092;Notch signaling pathway#P00045>TACE#P01105;Alzheimer disease-presenilin pathway#P00004>TACE#P00147 CIOIN|Ensembl=ENSCING00000014371.2|UniProtKB=F7AG49 F7AG49 PTHR15440:SF0 XRP2 PROTEIN PROTEIN XRP2 nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 localization#GO:0051179;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization#GO:0051234;Golgi vesicle transport#GO:0048193;post-Golgi vesicle-mediated transport#GO:0006892;transport#GO:0006810 membrane-bounded organelle#GO:0043227;plasma membrane region#GO:0098590;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;cilium#GO:0005929;organelle#GO:0043226;plasma membrane#GO:0005886 GTPase-activating protein#PC00257 CIOIN|Ensembl=ENSCING00000002871.3|UniProtKB=F6TMB1 F6TMB1 LOC100185465 PTHR22734:SF2 U3 SMALL NUCLEOLAR RIBONUCLEOPROTEIN PROTEIN IMP4 U3 SMALL NUCLEOLAR RIBONUCLEOPROTEIN PROTEIN IMP4 snoRNA binding#GO:0030515;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;small-subunit processome#GO:0032040;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;nuclear lumen#GO:0031981;90S preribosome#GO:0030686;nuclear protein-containing complex#GO:0140513 RNA splicing factor#PC00148;RNA processing factor#PC00147;RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000018392.1|UniProtKB=H2XKS7 H2XKS7 PTHR48017:SF48 OS05G0424000 PROTEIN-RELATED MAHOGANY CIOIN|Ensembl=ENSCING00000007228.3|UniProtKB=F6U952 F6U952 PTHR12370:SF3 PHOSPHOLIPASE B-RELATED PHOSPHOLIPASE B-LIKE 2-RELATED hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;phospholipase activity#GO:0004620;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;cellular metabolic process#GO:0044237;lipid catabolic process#GO:0016042;cellular process#GO:0009987;phospholipid metabolic process#GO:0006644;phosphorus metabolic process#GO:0006793;organophosphate catabolic process#GO:0046434;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;phospholipid catabolic process#GO:0009395;catabolic process#GO:0009056;organophosphate metabolic process#GO:0019637;organic substance catabolic process#GO:1901575;cellular lipid metabolic process#GO:0044255;cellular lipid catabolic process#GO:0044242;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 phospholipase#PC00186;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000021930.1|UniProtKB=H2XXQ5 H2XXQ5 spi_pu.1 PTHR11849:SF184 ETS ETS DOMAIN-CONTAINING PROTEIN transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 CIOIN|Ensembl=ENSCING00000014196.2|UniProtKB=F6ZPP9 F6ZPP9 LOC100180447 PTHR15726:SF7 RAB11-FAMILY INTERACTING PROTEIN NUCLEAR FALLOUT, ISOFORM J endosomal transport#GO:0016197;localization within membrane#GO:0051668;cellular localization#GO:0051641;vesicle-mediated transport to the plasma membrane#GO:0098876;transport#GO:0006810;vesicle-mediated transport#GO:0016192;regulation of cell division#GO:0051302;cellular process#GO:0009987;regulation of cell cycle process#GO:0010564;localization#GO:0051179;regulation of biological process#GO:0050789;endocytic recycling#GO:0032456;establishment of localization#GO:0051234;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;regulation of cytokinesis#GO:0032465 bounding membrane of organelle#GO:0098588;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;recycling endosome membrane#GO:0055038;organelle#GO:0043226;endosome membrane#GO:0010008;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;midbody#GO:0030496;recycling endosome#GO:0055037;cytoplasmic vesicle#GO:0031410;plasma membrane region#GO:0098590;membrane-bounded organelle#GO:0043227;cell division site#GO:0032153;endocytic vesicle#GO:0030139;cytoplasmic vesicle membrane#GO:0030659;plasma membrane#GO:0005886 CIOIN|Ensembl=ENSCING00000005331.3|UniProtKB=F7B670 F7B670 LOC100181174 PTHR20275:SF0 NAD KINASE NAD KINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301 cellular aromatic compound metabolic process#GO:0006725;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;pyridine nucleotide metabolic process#GO:0019362;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;nucleotide biosynthetic process#GO:0009165;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;pyridine-containing compound metabolic process#GO:0072524;NADP metabolic process#GO:0006739;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;nicotinamide nucleotide metabolic process#GO:0046496;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 nucleotide kinase#PC00172 CIOIN|Ensembl=ENSCING00000024650.1|UniProtKB=H2XY01 H2XY01 PTHR43570:SF16 ALDEHYDE DEHYDROGENASE ALDEHYDE DEHYDROGENASE TYPE III, ISOFORM Q oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 5-Hydroxytryptamine degredation#P04372>Aldehyde Dehydrogenase#P04402 CIOIN|Ensembl=ENSCING00000002048.3|UniProtKB=Q589R6 Q589R6 lasp PTHR46218:SF4 LASP LIM AND SH3 DOMAIN PROTEIN LASP CIOIN|Ensembl=ENSCING00000022695.1|UniProtKB=H2XKN6 H2XKN6 PTHR19143:SF394 FIBRINOGEN/TENASCIN/ANGIOPOEITIN ANGIOPOIETIN-RELATED PROTEIN 3-LIKE external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 CIOIN|Ensembl=ENSCING00000022070.1|UniProtKB=H2XXY2 H2XXY2 LOC100175595 PTHR24238:SF74 G-PROTEIN COUPLED RECEPTOR PROKINETICIN RECEPTOR 2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;neuropeptide receptor activity#GO:0008188;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;neuropeptide signaling pathway#GO:0007218;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 CIOIN|Ensembl=ENSCING00000003948.3|UniProtKB=F6ZLY9 F6ZLY9 PTHR15435:SF2 KICSTOR COMPLEX PROTEIN KAPTIN KICSTOR COMPLEX PROTEIN KAPTIN cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 negative regulation of biological process#GO:0048519;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;response to extracellular stimulus#GO:0009991;regulation of intracellular signal transduction#GO:1902531;negative regulation of TOR signaling#GO:0032007;regulation of biological process#GO:0050789;cellular response to starvation#GO:0009267;regulation of signal transduction#GO:0009966;negative regulation of cell communication#GO:0010648;negative regulation of cellular process#GO:0048523;cellular response to extracellular stimulus#GO:0031668;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of TORC1 signaling#GO:1903432;negative regulation of response to stimulus#GO:0048585;negative regulation of signaling#GO:0023057;cell communication#GO:0007154;response to nutrient levels#GO:0031667;cellular process#GO:0009987;regulation of TOR signaling#GO:0032006;regulation of response to stimulus#GO:0048583;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;response to stress#GO:0006950;cellular response to nutrient levels#GO:0031669;regulation of cellular process#GO:0050794;response to starvation#GO:0042594;biological regulation#GO:0065007;cellular response to external stimulus#GO:0071496;negative regulation of signal transduction#GO:0009968;cellular response to amino acid starvation#GO:0034198;cellular response to stress#GO:0033554;negative regulation of TORC1 signaling#GO:1904262 cell leading edge#GO:0031252;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;plasma membrane bounded cell projection#GO:0120025;lamellipodium#GO:0030027 CIOIN|Ensembl=ENSCING00000021667.1|UniProtKB=H2XUL2 H2XUL2 PTHR19969:SF5 SH2-SH3 ADAPTOR PROTEIN-RELATED CRK-LIKE PROTEIN molecular adaptor activity#GO:0060090;signaling adaptor activity#GO:0035591;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;protein tyrosine kinase binding#GO:1990782;receptor tyrosine kinase binding#GO:0030971;signaling receptor binding#GO:0005102;kinase binding#GO:0019900 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cell motility#GO:0048870;cellular process#GO:0009987;cell migration#GO:0016477;signaling#GO:0023052 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 Integrin signalling pathway#P00034>Crk#P00933;Angiogenesis#P00005>Crk#P00207 CIOIN|Ensembl=ENSCING00000020740.1|UniProtKB=H2XT04 H2XT04 vdr-a PTHR24082:SF283 NUCLEAR HORMONE RECEPTOR NUCLEAR HORMONE RECEPTOR HR96 cis-regulatory region sequence-specific DNA binding#GO:0000987;signaling receptor activity#GO:0038023;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular transducer activity#GO:0060089;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of nitrogen compound metabolic process#GO:0051173;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;positive regulation of RNA biosynthetic process#GO:1902680;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;positive regulation of biological process#GO:0048518;negative regulation of cellular process#GO:0048523;cellular developmental process#GO:0048869;negative regulation of biosynthetic process#GO:0009890;regulation of DNA-templated transcription#GO:0006355;negative regulation of metabolic process#GO:0009892;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;negative regulation of nitrogen compound metabolic process#GO:0051172;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;positive regulation of RNA metabolic process#GO:0051254;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 C4 zinc finger nuclear receptor#PC00169;zinc finger transcription factor#PC00244 CIOIN|Ensembl=ENSCING00000013789.2|UniProtKB=F6REB5 F6REB5 PTHR10166:SF37 VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2/DELTA-RELATED STOLID, ISOFORM H ion channel#PC00133;transporter#PC00227;voltage-gated ion channel#PC00241 CIOIN|Ensembl=ENSCING00000023536.1|UniProtKB=H2XXW3 H2XXW3 PTHR10192:SF5 MOLYBDOPTERIN BIOSYNTHESIS PROTEIN GEPHYRIN transferase activity#GO:0016740;catalytic activity#GO:0003824 heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;organophosphate biosynthetic process#GO:0090407;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;organophosphate metabolic process#GO:0019637;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000013445.2|UniProtKB=F6V2P6 F6V2P6 LOC101242339 PTHR10605:SF72 HEPARAN SULFATE SULFOTRANSFERASE HEPARAN SULFATE 3-O SULFOTRANSFERASE-B, ISOFORM A sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824 transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000024646.1|UniProtKB=H2XXT7 H2XXT7 PTHR13415:SF2 NUCLEAR FACTOR-RELATED INTEGRATOR COMPLEX SUBUNIT 12 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;snRNA metabolic process#GO:0016073;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;snRNA 3'-end processing#GO:0034472;snRNA processing#GO:0016180;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;integrator complex#GO:0032039 CIOIN|Ensembl=ENSCING00000000378.3|UniProtKB=F6VRB9 F6VRB9 PTHR46925:SF2 G-PROTEIN COUPLED RECEPTOR TKR-1-RELATED G-PROTEIN COUPLED RECEPTOR TKR-1-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled peptide receptor activity#GO:0008528;G protein-coupled receptor activity#GO:0004930;neuropeptide receptor activity#GO:0008188;transmembrane signaling receptor activity#GO:0004888 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 CIOIN|Ensembl=ENSCING00000007639.3|UniProtKB=F6WI80 F6WI80 LOC100178563 PTHR11771:SF153 LIPOXYGENASE LIPOXYGENASE DOMAIN-CONTAINING PROTEIN oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;dioxygenase activity#GO:0051213 lipid metabolic process#GO:0006629;lipid oxidation#GO:0034440;cellular metabolic process#GO:0044237;lipid modification#GO:0030258;cellular lipid metabolic process#GO:0044255;cellular process#GO:0009987;metabolic process#GO:0008152;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704 oxygenase#PC00177;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000012018.2|UniProtKB=F7B6S1 F7B6S1 PTHR45718:SF4 TRANSCRIPTIONAL ACTIVATOR CUBITUS INTERRUPTUS TRANSCRIPTIONAL ACTIVATOR CUBITUS INTERRUPTUS sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218 Hedgehog signaling pathway#P00025>Cubitus interruptus#P00690;Hedgehog signaling pathway#P00025>Cubitus interruptus repressor#P00687 CIOIN|Ensembl=ENSCING00000006696.3|UniProtKB=F7ARW8 F7ARW8 LOC100186478 PTHR13084:SF6 T-CELL LYMPHOMA BREAKPOINT-ASSOCIATED TARGET 1-RELATED SODIUM_POTASSIUM-TRANSPORTING ATPASE SUBUNIT BETA-1-INTERACTING PROTEIN biological regulation#GO:0065007;regulation of biological process#GO:0050789;regulation of localization#GO:0032879;regulation of monoatomic ion transport#GO:0043269;regulation of transport#GO:0051049;regulation of sodium ion transport#GO:0002028;regulation of metal ion transport#GO:0010959 CIOIN|Ensembl=ENSCING00000005866.3|UniProtKB=F6UG92 F6UG92 leprecan PTHR14049:SF9 LEPRECAN 1 PROCOLLAGEN-PROLINE 3-DIOXYGENASE extracellular matrix glycoprotein#PC00100 CIOIN|Ensembl=ENSCING00000021332.1|UniProtKB=H2XJH9 H2XJH9 LOC113474468 PTHR15114:SF1 REPLICATION PROTEIN A3 REPLICATION PROTEIN A 14 KDA SUBUNIT damaged DNA binding#GO:0003684;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;single-stranded DNA binding#GO:0003697;DNA binding#GO:0003677 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;nucleotide-excision repair#GO:0006289;cellular response to stimulus#GO:0051716;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;mismatch repair#GO:0006298;base-excision repair#GO:0006284;cellular nitrogen compound metabolic process#GO:0034641;double-strand break repair via homologous recombination#GO:0000724;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;response to stress#GO:0006950;nitrogen compound metabolic process#GO:0006807;recombinational repair#GO:0000725;DNA replication#GO:0006260;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;site of DNA damage#GO:0090734;protein-DNA complex#GO:0032993;replisome#GO:0030894;intracellular organelle lumen#GO:0070013;site of double-strand break#GO:0035861;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nuclear replication fork#GO:0043596;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513;replication fork#GO:0005657 Cell cycle#P00013>Pre-replication Complex#P00478 CIOIN|Ensembl=ENSCING00000000914.3|UniProtKB=F6U113 F6U113 PTHR45639:SF4 HSC70CB, ISOFORM G-RELATED HSC70CB, ISOFORM G macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein folding#GO:0006457;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 Hsp70 family chaperone#PC00027 CIOIN|Ensembl=ENSCING00000008124.3|UniProtKB=F6Y2V8 F6Y2V8 LOC100177208 PTHR16134:SF1 F-BOX/TPR REPEAT PROTEIN POF3 F-BOX AND LEUCINE-RICH PROTEIN 22 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 SCF ubiquitin ligase complex#GO:0019005;intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;cullin-RING ubiquitin ligase complex#GO:0031461;transferase complex#GO:1990234 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000021788.1|UniProtKB=H2XK45 H2XK45 PTHR24372:SF74 GLYCOPROTEIN HORMONE RECEPTOR LP13728P signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 response to organic substance#GO:0010033;positive regulation of adenylate cyclase activity#GO:0045762;regulation of lyase activity#GO:0051339;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;cellular response to stimulus#GO:0051716;regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;cellular response to endogenous stimulus#GO:0071495;cellular response to chemical stimulus#GO:0070887;positive regulation of catalytic activity#GO:0043085;cellular response to organic substance#GO:0071310;regulation of cyclase activity#GO:0031279;positive regulation of molecular function#GO:0044093;cell communication#GO:0007154;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;positive regulation of cyclase activity#GO:0031281;hormone-mediated signaling pathway#GO:0009755;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to endogenous stimulus#GO:0009719;response to hormone#GO:0009725;cellular response to hormone stimulus#GO:0032870;response to chemical#GO:0042221;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of lyase activity#GO:0051349;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 CIOIN|Ensembl=ENSCING00000002993.3|UniProtKB=Q4H3S6 Q4H3S6 Ci-CNOT7_8 PTHR10797:SF0 CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT POLY(A)-SPECIFIC RIBONUCLEASE catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;catalytic activity#GO:0003824;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters#GO:0016796;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity#GO:0016787;3'-5'-RNA exonuclease activity#GO:0000175;3'-5' exonuclease activity#GO:0008408;exonuclease activity#GO:0004527;RNA nuclease activity#GO:0004540 negative regulation of gene expression#GO:0010629;regulation of catabolic process#GO:0009894;heterocycle catabolic process#GO:0046700;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;nucleobase-containing compound metabolic process#GO:0006139;RNA destabilization#GO:0050779;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;regulation of RNA stability#GO:0043487;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;positive regulation of mRNA catabolic process#GO:0061014;regulation of cellular process#GO:0050794;post-transcriptional regulation of gene expression#GO:0010608;positive regulation of catabolic process#GO:0009896;mRNA destabilization#GO:0061157;nucleobase-containing compound catabolic process#GO:0034655;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;regulation of mRNA stability#GO:0043488;RNA metabolic process#GO:0016070;positive regulation of cellular catabolic process#GO:0031331;cellular nitrogen compound catabolic process#GO:0044270;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;mRNA catabolic process#GO:0006402;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;regulation of gene expression#GO:0010468;organic substance catabolic process#GO:1901575;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;positive regulation of mRNA metabolic process#GO:1903313;heterocycle metabolic process#GO:0046483;negative regulation of biosynthetic process#GO:0009890;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;positive regulation of RNA metabolic process#GO:0051254 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;protein-containing complex#GO:0032991;P-body#GO:0000932;CCR4-NOT complex#GO:0030014;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464;intracellular anatomical structure#GO:0005622 mRNA polyadenylation factor#PC00146 CIOIN|Ensembl=ENSCING00000003875.3|UniProtKB=F6XGL3 F6XGL3 PTHR24343:SF121 SERINE/THREONINE KINASE MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;phosphorylation#GO:0016310;protein phosphorylation#GO:0006468;cellular process#GO:0009987;protein metabolic process#GO:0019538;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000011580.2|UniProtKB=F6SP61 F6SP61 PTHR47131:SF1 CATION CHANNEL SPERM-ASSOCIATED PROTEIN 3 CATION CHANNEL SPERM-ASSOCIATED PROTEIN 3 calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;calcium channel activity#GO:0005262;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;channel activity#GO:0015267;voltage-gated calcium channel activity#GO:0005245;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;inorganic cation transmembrane transporter activity#GO:0022890 male gamete generation#GO:0048232;cellular process involved in reproduction in multicellular organism#GO:0022412;transport#GO:0006810;developmental process#GO:0032502;microtubule-based movement#GO:0007018;sperm motility#GO:0097722;spermatid differentiation#GO:0048515;cilium movement involved in cell motility#GO:0060294;cell differentiation#GO:0030154;establishment of localization#GO:0051234;spermatogenesis#GO:0007283;monoatomic cation transport#GO:0006812;reproductive process#GO:0022414;flagellated sperm motility#GO:0030317;multicellular organismal reproductive process#GO:0048609;sperm capacitation#GO:0048240;germ cell development#GO:0007281;cellular developmental process#GO:0048869;metal ion transport#GO:0030001;gamete generation#GO:0007276;multicellular organism reproduction#GO:0032504;cilium or flagellum-dependent cell motility#GO:0001539;cell motility#GO:0048870;cellular process#GO:0009987;cilium movement#GO:0003341;localization#GO:0051179;developmental process involved in reproduction#GO:0003006;cell development#GO:0048468;spermatid development#GO:0007286;cilium-dependent cell motility#GO:0060285;sodium ion transport#GO:0006814;reproduction#GO:0000003;microtubule-based process#GO:0007017;anatomical structure development#GO:0048856;sexual reproduction#GO:0019953;multicellular organismal process#GO:0032501;monoatomic ion transport#GO:0006811 membrane protein complex#GO:0098796;acrosomal vesicle#GO:0001669;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;transporter complex#GO:1990351;secretory granule#GO:0030141;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;calcium channel complex#GO:0034704;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cation channel complex#GO:0034703;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;voltage-gated calcium channel complex#GO:0005891;protein-containing complex#GO:0032991;CatSper complex#GO:0036128;endomembrane system#GO:0012505;monoatomic ion channel complex#GO:0034702;transmembrane transporter complex#GO:1902495;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 CIOIN|Ensembl=ENSCING00000014002.2|UniProtKB=F6RDF3 F6RDF3 LOC100178376 PTHR21656:SF2 MALE-SPECIFIC LETHAL-1 PROTEIN MALE-SPECIFIC LETHAL 1 HOMOLOG histone modifying enzyme#PC00261 CIOIN|Ensembl=ENSCING00000021902.1|UniProtKB=H2XYJ2 H2XYJ2 LOC100179714 PTHR10529:SF340 AP COMPLEX SUBUNIT MU CARMINE, ISOFORM A localization#GO:0051179;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization#GO:0051234;import into cell#GO:0098657;transport#GO:0006810;endocytosis#GO:0006897 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150 CIOIN|Ensembl=ENSCING00000012554.2|UniProtKB=F7AAZ2 F7AAZ2 LOC100176606 PTHR24115:SF576 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF17 pyrophosphatase activity#GO:0016462;cytoskeletal protein binding#GO:0008092;microtubule motor activity#GO:0003777;tubulin binding#GO:0015631;ATP-dependent activity#GO:0140657;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;cytoskeletal motor activity#GO:0003774;microtubule binding#GO:0008017;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;ribonucleoside triphosphate phosphatase activity#GO:0017111;ATP hydrolysis activity#GO:0016887 microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;microtubule associated complex#GO:0005875;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 CIOIN|Ensembl=ENSCING00000010054.3|UniProtKB=F6QH31 F6QH31 PTHR10036:SF25 CD59 GLYCOPROTEIN HEP21 PROTEIN CIOIN|Ensembl=ENSCING00000024929.1|UniProtKB=H2XPB4 H2XPB4 PTHR23316:SF87 IMPORTIN ALPHA IMPORTIN SUBUNIT ALPHA signal sequence binding#GO:0005048;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277 cellular localization#GO:0051641;NLS-bearing protein import into nucleus#GO:0006607;macromolecule localization#GO:0033036;transport#GO:0006810;protein localization to nucleus#GO:0034504;nitrogen compound transport#GO:0071705;establishment of protein localization to organelle#GO:0072594;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;protein import into nucleus#GO:0006606;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;protein localization to organelle#GO:0033365;nuclear transport#GO:0051169;import into nucleus#GO:0051170 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transporter#PC00227 CIOIN|Ensembl=ENSCING00000009434.3|UniProtKB=F6TKT6 F6TKT6 PTHR22802:SF456 C-TYPE LECTIN SUPERFAMILY MEMBER FI01427P membrane traffic protein#PC00150 CIOIN|Ensembl=ENSCING00000007191.3|UniProtKB=F6YRW6 F6YRW6 PTHR23503:SF132 SOLUTE CARRIER FAMILY 2 SOLUTE CARRIER FAMILY 2, FACILITATED GLUCOSE TRANSPORTER MEMBER 5-LIKE transmembrane transporter activity#GO:0022857;sugar transmembrane transporter activity#GO:0051119;transporter activity#GO:0005215;carbohydrate transmembrane transporter activity#GO:0015144 localization#GO:0051179;organic substance transport#GO:0071702;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;organic anion transport#GO:0015711;transport#GO:0006810;vitamin transport#GO:0051180;glucose transmembrane transport#GO:1904659;cellular process#GO:0009987;carbohydrate transmembrane transport#GO:0034219;carbohydrate transport#GO:0008643 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000022504.1|UniProtKB=H2XUF4 H2XUF4 PTHR11941:SF45 ENOYL-COA HYDRATASE-RELATED ENOYL-COA DELTA ISOMERASE 1, MITOCHONDRIAL oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;lipid oxidation#GO:0034440;cellular metabolic process#GO:0044237;lipid catabolic process#GO:0016042;lipid modification#GO:0030258;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;fatty acid catabolic process#GO:0009062;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;fatty acid metabolic process#GO:0006631;small molecule catabolic process#GO:0044282;fatty acid beta-oxidation#GO:0006635;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;cellular lipid metabolic process#GO:0044255;cellular lipid catabolic process#GO:0044242;carboxylic acid metabolic process#GO:0019752;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;monocarboxylic acid catabolic process#GO:0072329 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 hydratase#PC00120 CIOIN|Ensembl=ENSCING00000001176.3|UniProtKB=F6W8K8 F6W8K8 PTHR24031:SF307 RNA HELICASE ATP-DEPENDENT RNA HELICASE DDX1 RNA helicase#PC00032 CIOIN|Ensembl=ENSCING00000002925.3|UniProtKB=F7BJ92 F7BJ92 PTHR48013:SF17 DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 5-RELATED DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 7 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;response to stress#GO:0006950;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;MAPK cascade#GO:0000165;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;stress-activated MAPK cascade#GO:0051403;cellular process#GO:0009987;cellular response to stress#GO:0033554;signaling#GO:0023052 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Apoptosis signaling pathway#P00006>MKK7#P00312;Ras Pathway#P04393>MKK4/7#P04565;Huntington disease#P00029>MAPKK7#P00784;Gonadotropin-releasing hormone receptor pathway#P06664>MKK4/7#P06760;FGF signaling pathway#P00021>MKK4,7#P00637;EGF receptor signaling pathway#P00018>MKK4,7#P00555 CIOIN|Ensembl=ENSCING00000018992.1|UniProtKB=H2XK38 H2XK38 PTHR10896:SF65 GALACTOSYLGALACTOSYLXYLOSYLPROTEIN 3-BETA-GLUCURONOSYLTRANSFERASE BETA-1,3-GLUCURONYLTRANSFERASE GALACTOSYLGALACTOSYLXYLOSYLPROTEIN 3-BETA-GLUCURONOSYLTRANSFERASE 3 carbohydrate metabolic process#GO:0005975;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;primary metabolic process#GO:0044238 cytoplasm#GO:0005737;bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;Golgi membrane#GO:0000139;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111 CIOIN|Ensembl=ENSCING00000020514.1|UniProtKB=H2XVX5 H2XVX5 PTHR16222:SF23 ADP-RIBOSYLGLYCOHYDROLASE INACTIVE ADP-RIBOSYLTRANSFERASE ARH2 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000003102.3|UniProtKB=F6XAG7 F6XAG7 PTHR24253:SF103 TRANSMEMBRANE PROTEASE SERINE TRANSMEMBRANE PROTEASE SERINE 7 serine protease#PC00203;protease#PC00190 CIOIN|Ensembl=ENSCING00000014467.2|UniProtKB=F6YA88 F6YA88 LOC113474833 PTHR45704:SF16 RAS-LIKE FAMILY MEMBER 11 RAS-RELATED AND ESTROGEN-REGULATED GROWTH INHIBITOR CIOIN|Ensembl=ENSCING00000013810.2|UniProtKB=F6QRU4 F6QRU4 PTHR44085:SF2 SEPIAPTERIN REDUCTASE SEPIAPTERIN REDUCTASE oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 cellular aromatic compound metabolic process#GO:0006725;organic hydroxy compound metabolic process#GO:1901615;heterocycle metabolic process#GO:0046483;alcohol biosynthetic process#GO:0046165;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic hydroxy compound biosynthetic process#GO:1901617;alcohol metabolic process#GO:0006066;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;heterocycle biosynthetic process#GO:0018130;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;aromatic compound biosynthetic process#GO:0019438;small molecule biosynthetic process#GO:0044283;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 reductase#PC00198;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000014515.2|UniProtKB=F6XY64 F6XY64 LOC100178224 PTHR13568:SF9 FAM11A, B PROTEIN TRANSMEMBRANE PROTEIN 203 CIOIN|Ensembl=ENSCING00000006652.3|UniProtKB=F6U0K9 F6U0K9 PTHR12436:SF38 80 KDA MCM3-ASSOCIATED PROTEIN SAC3 DOMAIN-CONTAINING PROTEIN 1 cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;nucleic acid transport#GO:0050657;centrosome cycle#GO:0007098;nitrogen compound transport#GO:0071705;gene expression#GO:0010467;centrosome duplication#GO:0051298;biosynthetic process#GO:0009058;chromosome segregation#GO:0007059;RNA localization#GO:0006403;organic substance transport#GO:0071702;establishment of localization#GO:0051234;RNA transport#GO:0050658;spindle assembly#GO:0051225;cytoskeleton organization#GO:0007010;spindle organization#GO:0007051;non-membrane-bounded organelle assembly#GO:0140694;nuclear transport#GO:0051169;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;mRNA export from nucleus#GO:0006406;cellular component assembly#GO:0022607;macromolecule biosynthetic process#GO:0009059;establishment of RNA localization#GO:0051236;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular component organization#GO:0016043;organic substance biosynthetic process#GO:1901576;mRNA transport#GO:0051028;cellular process#GO:0009987;microtubule organizing center organization#GO:0031023;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;nuclear export#GO:0051168;organelle organization#GO:0006996;nucleocytoplasmic transport#GO:0006913;nucleobase-containing compound transport#GO:0015931;cell cycle#GO:0007049;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405 microtubule organizing center#GO:0005815;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;transcription export complex 2#GO:0070390;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;nuclear protein-containing complex#GO:0140513;spindle#GO:0005819 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000022542.1|UniProtKB=F6ZD00 F6ZD00 PTHR12111:SF2 SPLICING FACTOR YJU2 SPLICING FACTOR YJU2B-RELATED cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;U2-type spliceosomal complex#GO:0005684;cellular anatomical entity#GO:0110165;organelle#GO:0043226;post-mRNA release spliceosomal complex#GO:0071014;spliceosomal complex#GO:0005681;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA splicing factor#PC00148;RNA processing factor#PC00147;RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000007714.3|UniProtKB=F7A2D4 F7A2D4 PTHR10083:SF217 KUNITZ-TYPE PROTEASE INHIBITOR-RELATED BOOPHILIN-H2 peptidase inhibitor activity#GO:0030414;molecular function regulator activity#GO:0098772;serine-type endopeptidase inhibitor activity#GO:0004867;peptidase regulator activity#GO:0061134;enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;endopeptidase regulator activity#GO:0061135;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191;protein-binding activity modulator#PC00095 CIOIN|Ensembl=ENSCING00000013930.2|UniProtKB=F6PQ89 F6PQ89 PTHR23050:SF518 CALCIUM BINDING PROTEIN AT16150P-RELATED cation binding#GO:0043169;small molecule binding#GO:0036094;molecular function regulator activity#GO:0098772;binding#GO:0005488;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;enzyme regulator activity#GO:0030234 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 calmodulin-related#PC00061 B cell activation#P00010>Calmodulin#P00375;Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Calmodulin#P00755;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Phosphorylase b kinase#P00716;T cell activation#P00053>Calmodulin#P01305 CIOIN|Ensembl=ENSCING00000008831.3|UniProtKB=F6SDQ3 F6SDQ3 LOC100187445 PTHR24031:SF761 RNA HELICASE ATP-DEPENDENT RNA HELICASE DDX49-RELATED RNA helicase#PC00032 CIOIN|Ensembl=ENSCING00000009925.3|UniProtKB=F6RA21 F6RA21 PTHR24412:SF494 KELCH PROTEIN KELCH-LIKE PROTEIN 12 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000019756.1|UniProtKB=H2XVS4 H2XVS4 LOC100184449 PTHR23149:SF27 G PATCH DOMAIN CONTAINING PROTEIN PIN2_TERF1-INTERACTING TELOMERASE INHIBITOR 1 enzyme inhibitor activity#GO:0004857;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 membrane-enclosed lumen#GO:0031974;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000020901.1|UniProtKB=H2XP53 H2XP53 LOC108950184 PTHR31423:SF3 YBAK DOMAIN-CONTAINING PROTEIN PROLYL-TRNA SYNTHETASE ASSOCIATED DOMAIN-CONTAINING PROTEIN 1-RELATED CIOIN|Ensembl=ENSCING00000005829.3|UniProtKB=F6V779 F6V779 PTHR45953:SF1 IDURONATE 2-SULFATASE IDURONATE 2-SULFATASE hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000012799.1|UniProtKB=F6WQK5 F6WQK5 PTHR23334:SF69 CCAAT/ENHANCER BINDING PROTEIN CCAAT_ENHANCER-BINDING PROTEIN GAMMA sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 DNA-binding transcription factor#PC00218;basic leucine zipper transcription factor#PC00056 CIOIN|Ensembl=ENSCING00000003808.3|UniProtKB=A0A1W3JBY4 A0A1W3JBY4 LOC100175435 PTHR14964:SF2 NUCLEAR RECEPTOR BINDING FACTOR 2 NUCLEAR RECEPTOR-BINDING FACTOR 2 process utilizing autophagic mechanism#GO:0061919;cellular metabolic process#GO:0044237;catabolic process#GO:0009056;cellular process#GO:0009987;autophagy#GO:0006914;cellular catabolic process#GO:0044248;metabolic process#GO:0008152 transcription cofactor#PC00217 CIOIN|Ensembl=ENSCING00000001708.3|UniProtKB=F6UJ45 F6UJ45 PTHR43178:SF5 DIHYDROLIPOAMIDE ACETYLTRANSFERASE COMPONENT OF PYRUVATE DEHYDROGENASE COMPLEX LIPOAMIDE ACYLTRANSFERASE COMPONENT OF BRANCHED-CHAIN ALPHA-KETO ACID DEHYDROGENASE COMPLEX, MITOCHONDRIAL fatty acid binding#GO:0005504;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acetyltransferase activity#GO:0016407;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;carboxylic acid binding#GO:0031406;heterocyclic compound binding#GO:1901363;lipid binding#GO:0008289;anion binding#GO:0043168;ion binding#GO:0043167;organic acid binding#GO:0043177 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 transferase#PC00220;acetyltransferase#PC00038;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000015048.2|UniProtKB=F6TMW8 F6TMW8 PTHR24064:SF650 SOLUTE CARRIER FAMILY 22 MEMBER MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000014014.2|UniProtKB=F6QW82 F6QW82 PTHR13507:SF0 PRKR-INTERACTING PROTEIN 1 PRKR-INTERACTING PROTEIN 1 nucleic acid binding#GO:0003676;protein kinase regulator activity#GO:0019887;molecular function regulator activity#GO:0098772;binding#GO:0005488;enzyme binding#GO:0019899;enzyme inhibitor activity#GO:0004857;kinase regulator activity#GO:0019207;enzyme regulator activity#GO:0030234;kinase binding#GO:0019900;RNA binding#GO:0003723;organic cyclic compound binding#GO:0097159;protein binding#GO:0005515;protein kinase binding#GO:0019901;molecular function inhibitor activity#GO:0140678;double-stranded RNA binding#GO:0003725;protein kinase inhibitor activity#GO:0004860 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;regulation of catalytic activity#GO:0050790;negative regulation of protein phosphorylation#GO:0001933;regulation of phosphorus metabolic process#GO:0051174;regulation of biological process#GO:0050789;negative regulation of protein modification process#GO:0031400;regulation of molecular function#GO:0065009;negative regulation of protein kinase activity#GO:0006469;negative regulation of cellular process#GO:0048523;regulation of kinase activity#GO:0043549;regulation of protein kinase activity#GO:0045859;negative regulation of phosphorus metabolic process#GO:0010563;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of primary metabolic process#GO:0080090;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of phosphorylation#GO:0042326;regulation of protein phosphorylation#GO:0001932;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of phosphate metabolic process#GO:0045936;regulation of phosphorylation#GO:0042325;negative regulation of catalytic activity#GO:0043086;regulation of transferase activity#GO:0051338;regulation of metabolic process#GO:0019222;negative regulation of molecular function#GO:0044092;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Gene=CALM_CIOIN|UniProtKB=O02367 O02367 PTHR23050:SF530 CALCIUM BINDING PROTEIN CALMODULIN cation binding#GO:0043169;small molecule binding#GO:0036094;molecular function regulator activity#GO:0098772;binding#GO:0005488;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;enzyme regulator activity#GO:0030234 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 calmodulin-related#PC00061 CIOIN|Ensembl=ENSCING00000022489.1|UniProtKB=H2Y2X4 H2Y2X4 zf(cchc)-26 PTHR47266:SF19 ENDONUCLEASE-RELATED INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000009522.3|UniProtKB=F6WWV8 F6WWV8 LOC100176155 PTHR19981:SF1 TALIN RHEA, ISOFORM B cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;organelle organization#GO:0006996;cell-cell adhesion#GO:0098609;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cell adhesion#GO:0007155;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987 cytoplasm#GO:0005737;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 Integrin signalling pathway#P00034>Talin#P00943 CIOIN|Ensembl=ENSCING00000012717.2|UniProtKB=F7ATB7 F7ATB7 PTHR22802:SF396 C-TYPE LECTIN SUPERFAMILY MEMBER C-TYPE LECTIN DOMAIN-CONTAINING PROTEIN membrane traffic protein#PC00150 CIOIN|Ensembl=ENSCING00000019661.1|UniProtKB=H2XKL0 H2XKL0 PTHR11040:SF140 ZINC/IRON TRANSPORTER ZRT (ZRT), IRT- (IRT-) LIKE PROTEIN TRANSPORTER inorganic molecular entity transmembrane transporter activity#GO:0015318;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;inorganic cation transmembrane transporter activity#GO:0022890;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075 localization#GO:0051179;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;monoatomic cation transport#GO:0006812;transition metal ion transport#GO:0000041;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655 cellular anatomical entity#GO:0110165;membrane#GO:0016020 secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000013574.2|UniProtKB=F6XNR6 F6XNR6 PTHR20905:SF1 N-ACETYLTRANSFERASE-RELATED AT07410P-RELATED acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;N-acetyltransferase activity#GO:0008080;acyltransferase activity#GO:0016746;acetyltransferase activity#GO:0016407;catalytic activity#GO:0003824;N-acyltransferase activity#GO:0016410 acetyltransferase#PC00038 CIOIN|Ensembl=ENSCING00000011434.2|UniProtKB=F7AD70 F7AD70 PTHR10887:SF419 DNA2/NAM7 HELICASE FAMILY RNA HELICASE MOV10L1 negative regulation of gene expression#GO:0010629;regulatory ncRNA-mediated gene silencing#GO:0031047;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of biosynthetic process#GO:0009890;negative regulation of metabolic process#GO:0009892;regulation of biological process#GO:0050789;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulatory ncRNA-mediated post-transcriptional gene silencing#GO:0035194;regulation of cellular process#GO:0050794;regulation of biosynthetic process#GO:0009889;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;P granule#GO:0043186;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464;intracellular anatomical structure#GO:0005622 RNA helicase#PC00032 CIOIN|Ensembl=ENSCING00000021704.1|UniProtKB=H2XVW6 H2XVW6 PTHR11640:SF31 NEPHRIN IRREGULAR CHIASM C-ROUGHEST PROTEIN-RELATED cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;binding#GO:0005488 cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987 cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;plasma membrane#GO:0005886 immunoglobulin superfamily cell adhesion molecule#PC00125;cell adhesion molecule#PC00069 CIOIN|Ensembl=ENSCING00000003620.3|UniProtKB=F6U8C7 F6U8C7 LOC100182767 PTHR14068:SF0 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 EIF3 -RELATED EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT B nucleic acid binding#GO:0003676;translation regulator activity#GO:0045182;translation regulator activity, nucleic acid binding#GO:0090079;binding#GO:0005488;organic cyclic compound binding#GO:0097159;translation initiation factor activity#GO:0003743;translation factor activity, RNA binding#GO:0008135 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;translational initiation#GO:0006413;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;eukaryotic translation initiation factor 3 complex#GO:0005852;intracellular anatomical structure#GO:0005622 translation initiation factor#PC00224;translation factor#PC00223;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000019436.1|UniProtKB=H2XLG9 H2XLG9 LOC100178013 PTHR31248:SF2 DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G04290)-RELATED DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G04290)-RELATED CIOIN|Ensembl=ENSCING00000013825.2|UniProtKB=F6QLU5 F6QLU5 LOC100177176 PTHR48068:SF4 TAF9 RNA POLYMERASE II, TATA BOX-BINDING PROTEIN (TBP)-ASSOCIATED FACTOR TATA-BOX BINDING PROTEIN ASSOCIATED FACTOR 9 transcription coactivator activity#GO:0003713;molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;protein-macromolecule adaptor activity#GO:0030674 cellular aromatic compound metabolic process#GO:0006725;DNA-templated transcription#GO:0006351;cellular component biogenesis#GO:0044085;protein-DNA complex organization#GO:0071824;RNA metabolic process#GO:0016070;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;protein-DNA complex assembly#GO:0065004;nucleobase-containing compound metabolic process#GO:0006139;RNA polymerase II preinitiation complex assembly#GO:0051123;transcription initiation at RNA polymerase II promoter#GO:0006367;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;DNA-templated transcription initiation#GO:0006352;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular component assembly#GO:0022607;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;protein-containing complex organization#GO:0043933;aromatic compound biosynthetic process#GO:0019438;transcription by RNA polymerase II#GO:0006366 histone acetyltransferase complex#GO:0000123;DNA-directed RNA polymerase complex#GO:0000428;acetyltransferase complex#GO:1902493;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;RNA polymerase II, holoenzyme#GO:0016591;non-membrane-bounded organelle#GO:0043228;chromosome#GO:0005694;nuclear DNA-directed RNA polymerase complex#GO:0055029;SAGA complex#GO:0000124;membrane-enclosed lumen#GO:0031974;SAGA-type complex#GO:0070461;peptidase complex#GO:1905368;organelle lumen#GO:0043233;nucleus#GO:0005634;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;protein-DNA complex#GO:0032993;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;RNA polymerase II transcription regulator complex#GO:0090575;transcription factor TFIID complex#GO:0005669;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;protein acetyltransferase complex#GO:0031248;RNA polymerase complex#GO:0030880;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 General transcription regulation#P00023>TBP-associated factors#P00658;Transcription regulation by bZIP transcription factor#P00055>TBP-associated factors#P01385 CIOIN|Ensembl=ENSCING00000006946.3|UniProtKB=F6VN25 F6VN25 PTHR14396:SF10 CLASPIN CLASPIN CIOIN|Ensembl=ENSCING00000020878.1|UniProtKB=Q5QHQ8 Q5QHQ8 dazap2-like PTHR31638:SF3 DAZ-ASSOCIATED PROTEIN 2 DAZ-ASSOCIATED PROTEIN 2 CIOIN|Ensembl=ENSCING00000006667.3|UniProtKB=F6TDK2 F6TDK2 PTHR28663:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 173 CILIA- AND FLAGELLA- ASSOCIATED PROTEIN 210 CIOIN|Ensembl=ENSCING00000000810.3|UniProtKB=F6RP59 F6RP59 brachyury PTHR11267:SF106 T-BOX PROTEIN-RELATED T-RELATED PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cell fate commitment#GO:0045165;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;cell fate specification#GO:0001708;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;Rel homology transcription factor#PC00252;immunoglobulin fold transcription factor#PC00251 Wnt signaling pathway#P00057>Wnt Target Genes#G01558 CIOIN|Ensembl=ENSCING00000006685.3|UniProtKB=F7BAE5 F7BAE5 LOC100175014 PTHR14009:SF13 LEUCINE ZIPPER-EF-HAND CONTAINING TRANSMEMBRANE PROTEIN LETM1 DOMAIN-CONTAINING PROTEIN 1 intracellular monoatomic cation homeostasis#GO:0030003;homeostatic process#GO:0042592;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic ion homeostasis#GO:0006873;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;intracellular chemical homeostasis#GO:0055082;monoatomic ion homeostasis#GO:0050801 secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000006421.3|UniProtKB=F6QS75 F6QS75 PTHR17920:SF3 TRANSMEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 4 TMCO4 TRANSMEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 4 CIOIN|Ensembl=ENSCING00000021147.1|UniProtKB=H2XRZ5 H2XRZ5 PTHR46593:SF1 TRANSMEMBRANE PROTEIN 64 TRANSMEMBRANE PROTEIN 64 inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;homeostatic process#GO:0042592;intracellular monoatomic ion homeostasis#GO:0006873;chemical homeostasis#GO:0048878;regulation of cytosolic calcium ion concentration#GO:0051480;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;monoatomic ion homeostasis#GO:0050801 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000002848.3|UniProtKB=F6TND1 F6TND1 LOC100177894 PTHR10501:SF41 U1 SMALL NUCLEAR RIBONUCLEOPROTEIN A/U2 SMALL NUCLEAR RIBONUCLEOPROTEIN B PROTEIN COUCH POTATO nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 RNA splicing factor#PC00148;RNA metabolism protein#PC00031;RNA processing factor#PC00147 CIOIN|Ensembl=ENSCING00000016214.2|UniProtKB=F6ZRT4 F6ZRT4 PTHR23071:SF1 PHOSPHATIDYLINOSITOL GLYCAN GPI ETHANOLAMINE PHOSPHATE TRANSFERASE 3 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;phospholipid biosynthetic process#GO:0008654;macromolecule modification#GO:0043412;organophosphate biosynthetic process#GO:0090407;phosphatidylinositol biosynthetic process#GO:0006661;glycolipid metabolic process#GO:0006664;protein modification process#GO:0036211;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;lipid biosynthetic process#GO:0008610;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;protein lipidation#GO:0006497;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;glycerolipid biosynthetic process#GO:0045017;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;glycerophospholipid metabolic process#GO:0006650;phosphatidylinositol metabolic process#GO:0046488;organic substance biosynthetic process#GO:1901576;liposaccharide metabolic process#GO:1903509;cellular process#GO:0009987;GPI anchor metabolic process#GO:0006505;membrane lipid biosynthetic process#GO:0046467;lipoprotein biosynthetic process#GO:0042158;primary metabolic process#GO:0044238;GPI anchor biosynthetic process#GO:0006506;carbohydrate derivative biosynthetic process#GO:1901137;membrane lipid metabolic process#GO:0006643;glycerophospholipid biosynthetic process#GO:0046474;glycolipid biosynthetic process#GO:0009247;organophosphate metabolic process#GO:0019637;lipoprotein metabolic process#GO:0042157;cellular lipid metabolic process#GO:0044255 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000002476.3|UniProtKB=F7B4J3 F7B4J3 PTHR11214:SF283 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE N-ACETYLLACTOSAMINIDE BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE 4-LIKE transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;protein O-linked glycosylation#GO:0006493;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 bounding membrane of organelle#GO:0098588;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;Golgi membrane#GO:0000139;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111 CIOIN|Ensembl=ENSCING00000018243.1|UniProtKB=H2XX91 H2XX91 LOC100177979 PTHR28656:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 153 COILED-COIL DOMAIN-CONTAINING PROTEIN 153 CIOIN|Ensembl=ENSCING00000019920.1|UniProtKB=H2Y0T4 H2Y0T4 PTHR34490:SF3 PROTEIN CBG12054-RELATED GALAXIN-LIKE ISOFORM X2 CIOIN|Ensembl=ENSCING00000000514.3|UniProtKB=F6V136 F6V136 PTHR10644:SF2 DNA REPAIR/RNA PROCESSING CPSF FAMILY CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 1 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA processing factor#PC00147 CIOIN|Ensembl=ENSCING00000008854.4|UniProtKB=F6R3M6 F6R3M6 PTHR10680:SF14 PEPTIDYL-GLYCINE ALPHA-AMIDATING MONOOXYGENASE PEPTIDYL-GLYCINE ALPHA-AMIDATING MONOOXYGENASE oxygenase#PC00177 Vasopressin synthesis#P04395>Amidating Enzyme#P04599 CIOIN|Ensembl=ENSCING00000006530.3|UniProtKB=F6PH03 F6PH03 ci-cadherin PTHR24027:SF422 CADHERIN-23 CADHERIN DOMAIN-CONTAINING PROTEIN cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;binding#GO:0005488;beta-catenin binding#GO:0008013 cellular component assembly#GO:0022607;cell-cell junction organization#GO:0045216;cellular component biogenesis#GO:0044085;cell-cell junction assembly#GO:0007043;developmental process#GO:0032502;multicellular organism development#GO:0007275;cell-cell adhesion via plasma-membrane adhesion molecules#GO:0098742;cell-cell adhesion#GO:0098609;cell morphogenesis#GO:0000902;cell motility#GO:0048870;cell adhesion#GO:0007155;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;cell junction organization#GO:0034330;cell junction assembly#GO:0034329;multicellular organismal process#GO:0032501;cell migration#GO:0016477;adherens junction organization#GO:0034332 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;anchoring junction#GO:0070161;cell-cell junction#GO:0005911;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;adherens junction#GO:0005912;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;extrinsic component of membrane#GO:0019898 cadherin#PC00057 CIOIN|Ensembl=ENSCING00000004897.3|UniProtKB=F7B9H1 F7B9H1 LOC100183084 PTHR13531:SF6 GEO07735P1-RELATED-RELATED TMEM (HUMAN TRANSMEMBRANE PROTEIN) HOMOLOG organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;non-motile cilium assembly#GO:1905515;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cell projection organization#GO:0030030;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cilium#GO:0005929;ciliary transition zone#GO:0035869 CIOIN|Ensembl=ENSCING00000024440.1|UniProtKB=H2Y2I8 H2Y2I8 PTHR10846:SF72 SODIUM/POTASSIUM/CALCIUM EXCHANGER SODIUM_POTASSIUM_CALCIUM EXCHANGER NCKX30C calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;antiporter activity#GO:0015297;calcium channel activity#GO:0005262;potassium ion transmembrane transporter activity#GO:0015079;sodium ion transmembrane transporter activity#GO:0015081;monoatomic cation transmembrane transporter activity#GO:0008324;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;channel activity#GO:0015267;secondary active transmembrane transporter activity#GO:0015291;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;active monoatomic ion transmembrane transporter activity#GO:0022853;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;calcium ion transmembrane transport#GO:0070588;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;homeostatic process#GO:0042592;monoatomic cation homeostasis#GO:0055080;inorganic ion transmembrane transport#GO:0098660;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;cellular process#GO:0009987;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;calcium ion transport#GO:0006816;monoatomic ion homeostasis#GO:0050801;localization#GO:0051179;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation transport#GO:0006812;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000014102.2|UniProtKB=F6TD74 F6TD74 PTHR35081:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 105 COILED-COIL DOMAIN-CONTAINING PROTEIN 105 CIOIN|Ensembl=ENSCING00000018863.1|UniProtKB=H2XQ52 H2XQ52 PTHR19325:SF558 COMPLEMENT COMPONENT-RELATED SUSHI DOMAIN-CONTAINING PROTEIN LEV-9 complement component#PC00078 CIOIN|Ensembl=ENSCING00000016647.2|UniProtKB=F6PMY2 F6PMY2 PTHR11943:SF1 GALACTOSE-1-PHOSPHATE URIDYLYLTRANSFERASE GALACTOSE-1-PHOSPHATE URIDYLYLTRANSFERASE transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779 monosaccharide metabolic process#GO:0005996;small molecule catabolic process#GO:0044282;carbohydrate catabolic process#GO:0016052;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;hexose metabolic process#GO:0019318;carbohydrate metabolic process#GO:0005975;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 nucleotidyltransferase#PC00174 Fructose galactose metabolism#P02744>Hexose 1-P uridyltransferase#P02964;Interleukin signaling pathway#P00036>Receptor subunit alpha#P00992 CIOIN|Ensembl=ENSCING00000020142.1|UniProtKB=H2XZD1 H2XZD1 PTHR34400:SF4 FAMILY NOT NAMED MEMBRANE PROTEIN CIOIN|Ensembl=ENSCING00000002669.3|UniProtKB=F6YCW2 F6YCW2 LOC100175770 PTHR45620:SF1 PDF RECEPTOR-LIKE PROTEIN-RELATED G-PROTEIN COUPLED RECEPTORS FAMILY 2 PROFILE 2 DOMAIN-CONTAINING PROTEIN signaling receptor activity#GO:0038023;peptide hormone binding#GO:0017046;binding#GO:0005488;peptide binding#GO:0042277;amide binding#GO:0033218;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled peptide receptor activity#GO:0008528;hormone binding#GO:0042562;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 CIOIN|Ensembl=ENSCING00000006594.3|UniProtKB=F6QW24 F6QW24 LOC100185524 PTHR10127:SF901 DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING METALLOENDOPEPTIDASE hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000020986.1|UniProtKB=H2XM23 H2XM23 LOC100177728 PTHR24002:SF3 SOLUTE CARRIER FAMILY 22 MEMBER 18 SOLUTE CARRIER FAMILY 22 MEMBER 18 localization#GO:0051179;establishment of localization#GO:0051234;transport#GO:0006810 envelope#GO:0031975;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear envelope#GO:0005635;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000018660.1|UniProtKB=H2Y393 H2Y393 PTHR24246:SF27 OLFACTORY RECEPTOR AND ADENOSINE RECEPTOR ADENOSINE RECEPTOR, ISOFORM A G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711 CIOIN|Ensembl=ENSCING00000003120.3|UniProtKB=F6RCP1 F6RCP1 LOC100186563 PTHR10340:SF34 SPHINGOMYELIN PHOSPHODIESTERASE SPHINGOMYELIN PHOSPHODIESTERASE hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphoric diester hydrolase activity#GO:0008081;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 phosphodiesterase#PC00185;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000021396.1|UniProtKB=F6TB46 F6TB46 PTHR10010:SF46 SOLUTE CARRIER FAMILY 34 SODIUM PHOSPHATE , MEMBER 2-RELATED SODIUM-DEPENDENT PHOSPHATE TRANSPORT PROTEIN 2B secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000003998.3|UniProtKB=F6VYM6 F6VYM6 LOC100176560 PTHR11071:SF561 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE D-RELATED peptidyl-prolyl cis-trans isomerase activity#GO:0003755;isomerase activity#GO:0016853;catalytic activity, acting on a protein#GO:0140096;binding#GO:0005488;catalytic activity#GO:0003824;peptide binding#GO:0042277;amide binding#GO:0033218 macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein peptidyl-prolyl isomerization#GO:0000413;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein folding#GO:0006457;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 chaperone#PC00072 CIOIN|Ensembl=ENSCING00000016144.2|UniProtKB=F6YNN5 F6YNN5 PTHR24251:SF30 OVOCHYMASE-RELATED MEMBRANE FRIZZLED-RELATED PROTEIN serine protease#PC00203;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000012328.2|UniProtKB=F6ZDG8 F6ZDG8 LOC100182355 PTHR22146:SF8 CAT EYE SYNDROME CRITICAL REGION PROTEIN 6 PROTEIN FAM166B CIOIN|Ensembl=ENSCING00000005696.3|UniProtKB=F6WQJ7 F6WQJ7 PTHR43684:SF1 FAMILY NOT NAMED ENOYL-COA DELTA ISOMERASE 2 CIOIN|Ensembl=ENSCING00000015685.2|UniProtKB=F6WIN9 F6WIN9 LOC100187429 PTHR19305:SF14 SYNAPTOSOMAL ASSOCIATED PROTEIN SYNAPTOSOMAL-ASSOCIATED PROTEIN-RELATED syntaxin binding#GO:0019905;molecular adaptor activity#GO:0060090;protein binding#GO:0005515;SNAP receptor activity#GO:0005484;binding#GO:0005488;SNARE binding#GO:0000149;protein-macromolecule adaptor activity#GO:0030674 vesicle fusion#GO:0006906;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;synaptic vesicle cycle#GO:0099504;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;transport#GO:0006810;protein-containing complex assembly#GO:0065003;endomembrane system organization#GO:0010256;regulation of biological process#GO:0050789;regulated exocytosis#GO:0045055;chemical synaptic transmission#GO:0007268;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;secretion#GO:0046903;neurotransmitter transport#GO:0006836;synaptic signaling#GO:0099536;signal release#GO:0023061;vesicle organization#GO:0016050;cell-cell signaling#GO:0007267;signaling#GO:0023052;synaptic vesicle exocytosis#GO:0016079;secretion by cell#GO:0032940;organelle fusion#GO:0048284;vesicle fusion to plasma membrane#GO:0099500;neurotransmitter secretion#GO:0007269;cellular component assembly#GO:0022607;trans-synaptic signaling#GO:0099537;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;cellular process#GO:0009987;exocytic process#GO:0140029;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;signal release from synapse#GO:0099643;membrane fusion#GO:0061025;exocytosis#GO:0006887;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;export from cell#GO:0140352;vesicle-mediated transport in synapse#GO:0099003 cytoplasm#GO:0005737;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;SNARE complex#GO:0031201;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 SNARE protein#PC00034 Synaptic vesicle trafficking#P05734>SNAP-25#P05778;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>SNARE Complex#P01066;Opioid proenkephalin pathway#P05915>SNARE Complex#P05986;Thyrotropin-releasing hormone receptor signaling pathway#P04394>SNARE Complex#P04582;Dopamine receptor mediated signaling pathway#P05912>SNARE Complex#P05956;Adrenaline and noradrenaline biosynthesis#P00001>SNARE#P00072;Beta3 adrenergic receptor signaling pathway#P04379>SNARE Complex#P04447;5HT4 type receptor mediated signaling pathway#P04376>SNARE Complex#P04428;Opioid prodynorphin pathway#P05916>SNARE Complex#P05996;Alpha adrenergic receptor signaling pathway#P00002>SNARE#P00074;Nicotinic acetylcholine receptor signaling pathway#P00044>SNARE Complex#P01091;5HT3 type receptor mediated signaling pathway#P04375>SNARE Complex#P04423;Ionotropic glutamate receptor pathway#P00037>SNARE Complex#P01013;Metabotropic glutamate receptor group II pathway#P00040>SNARE Complex#P01049;Opioid proopiomelanocortin pathway#P05917>SNARE Complex#P06005;Cortocotropin releasing factor receptor signaling pathway#P04380>SNARE Complex#P04457;Beta1 adrenergic receptor signaling pathway#P04377>SNARE Complex#P04435;Oxytocin receptor mediated signaling pathway#P04391>SNARE Complex#P04532;Metabotropic glutamate receptor group III pathway#P00039>SNARE Complex#P01042;5HT2 type receptor mediated signaling pathway#P04374>SNARE Complex#P04415;5HT1 type receptor mediated signaling pathway#P04373>SNARE Complex#P04405;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>SNARE Complex#P01079;Beta2 adrenergic receptor signaling pathway#P04378>SNARE Complex#P04442 CIOIN|Ensembl=ENSCING00000008320.2|UniProtKB=F6Q7X0 F6Q7X0 PTHR46035:SF1 TETRATRICOPEPTIDE REPEAT PROTEIN 4 TETRATRICOPEPTIDE REPEAT PROTEIN 4 protein binding#GO:0005515;heat shock protein binding#GO:0031072;protein-folding chaperone binding#GO:0051087;binding#GO:0005488;Hsp70 protein binding#GO:0030544;Hsp90 protein binding#GO:0051879 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein folding#GO:0006457;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000004530.3|UniProtKB=F7A927 F7A927 PTHR11616:SF309 SODIUM/CHLORIDE DEPENDENT TRANSPORTER TRANSPORTER metal ion transport#GO:0030001;transmembrane transport#GO:0055085;amino acid transport#GO:0006865;organic anion transport#GO:0015711;organic acid transport#GO:0015849;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;localization#GO:0051179;organic substance transport#GO:0071702;sodium ion transport#GO:0006814;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;sodium ion transmembrane transport#GO:0035725 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 primary active transporter#PC00068;transporter#PC00227 CIOIN|Ensembl=ENSCING00000018663.1|UniProtKB=H2XVY9 H2XVY9 PTHR11360:SF313 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER 13-LIKE ISOFORM X1 transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;monocarboxylic acid transmembrane transporter activity#GO:0008028;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215;organic acid transmembrane transporter activity#GO:0005342 localization#GO:0051179;monocarboxylic acid transport#GO:0015718;organic substance transport#GO:0071702;establishment of localization#GO:0051234;organic anion transport#GO:0015711;organic acid transport#GO:0015849;transport#GO:0006810;carboxylic acid transport#GO:0046942 basal plasma membrane#GO:0009925;basolateral plasma membrane#GO:0016323;plasma membrane region#GO:0098590;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;basal part of cell#GO:0045178;plasma membrane#GO:0005886 transporter#PC00227 CIOIN|Ensembl=ENSCING00000005988.3|UniProtKB=F6V5Y1 F6V5Y1 LOC100183815 PTHR10961:SF46 PEROXISOMAL SARCOSINE OXIDASE PEROXISOMAL SARCOSINE OXIDASE oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 oxidase#PC00175;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000022702.1|UniProtKB=F6R9G4 F6R9G4 PTHR23048:SF49 MYOSIN LIGHT CHAIN 1, 3 FI08416P-RELATED intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;myosin complex#GO:0016459;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 CIOIN|Ensembl=ENSCING00000007614.3|UniProtKB=L7N0T4 L7N0T4 PTHR43511:SF4 FAMILY NOT NAMED UTP--GLUCOSE-1-PHOSPHATE URIDYLYLTRANSFERASE CIOIN|Ensembl=ENSCING00000018712.1|UniProtKB=H2XMA9 H2XMA9 PTHR12868:SF0 NADH-UBIQUINONE OXIDOREDUCTASE B22 SUBUNIT NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 9 envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;respiratory chain complex#GO:0098803;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transporter complex#GO:1990351;oxidoreductase complex#GO:1990204;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;respirasome#GO:0070469;mitochondrial respiratory chain complex I#GO:0005747;protein-containing complex#GO:0032991;mitochondrial envelope#GO:0005740;inner mitochondrial membrane protein complex#GO:0098800;transmembrane transporter complex#GO:1902495;mitochondrial respirasome#GO:0005746;membrane-bounded organelle#GO:0043227;respiratory chain complex I#GO:0045271;NADH dehydrogenase complex#GO:0030964;mitochondrial protein-containing complex#GO:0098798 oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000004421.3|UniProtKB=F6Y4I3 F6Y4I3 PTHR24251:SF30 OVOCHYMASE-RELATED MEMBRANE FRIZZLED-RELATED PROTEIN serine protease#PC00203;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000023668.1|UniProtKB=H2Y265 H2Y265 LOC100184395 PTHR45615:SF27 MYOSIN HEAVY CHAIN, NON-MUSCLE MYOSIN HEAVY CHAIN, MUSCLE microfilament motor activity#GO:0000146;cytoskeletal protein binding#GO:0008092;ATP-dependent activity#GO:0140657;binding#GO:0005488;actin filament binding#GO:0051015;cytoskeletal motor activity#GO:0003774;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779 supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;supramolecular fiber#GO:0099512;supramolecular polymer#GO:0099081;myosin complex#GO:0016459;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 CIOIN|Ensembl=ENSCING00000008412.3|UniProtKB=F6X313 F6X313 PTHR12546:SF33 FER-1-LIKE SPERM VESICLE FUSION PROTEIN FER-1 endomembrane system organization#GO:0010256;cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;cellular process#GO:0009987;membrane organization#GO:0061024;plasma membrane organization#GO:0007009 membrane trafficking regulatory protein#PC00151 CIOIN|Ensembl=ENSCING00000016182.2|UniProtKB=F6S6V5 F6S6V5 LOC100176430 PTHR45697:SF3 ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 2-RELATED DEAD END carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;anion binding#GO:0043168 organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cell projection organization#GO:0030030;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000002869.3|UniProtKB=F6T143 F6T143 LOC100181746 PTHR23122:SF42 MEMBRANE-ASSOCIATED GUANYLATE KINASE MAGUK MENAGE A TROIS, ISOFORM A cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000006883.3|UniProtKB=F6YUQ8 F6YUQ8 PTHR10410:SF41 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 -RELATED MPN DOMAIN-CONTAINING PROTEIN metallopeptidase activity#GO:0008237;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;protein binding#GO:0005515;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;modification-dependent protein binding#GO:0140030;polyubiquitin modification-dependent protein binding#GO:0031593 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;DNA damage response#GO:0006974;response to stress#GO:0006950;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular response to stress#GO:0033554;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;BRCA1-A complex#GO:0070531;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 translation initiation factor#PC00224;translation factor#PC00223 CIOIN|Ensembl=ENSCING00000021519.1|UniProtKB=H2XJN2 H2XJN2 PTHR46239:SF1 DNA REPAIR PROTEIN RAD51 HOMOLOG 3 RAD51C DNA REPAIR PROTEIN RAD51 HOMOLOG 3 hydrolase activity, acting on ester bonds#GO:0016788;DNA endonuclease activity#GO:0004520;nucleic acid binding#GO:0003676;nuclease activity#GO:0004518;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;endonuclease activity#GO:0004519;hydrolase activity#GO:0016787;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on DNA#GO:0140097;DNA nuclease activity#GO:0004536;four-way junction DNA binding#GO:0000400 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;protein-DNA complex organization#GO:0071824;double-strand break repair#GO:0006302;nuclear division#GO:0000280;cell cycle process#GO:0022402;protein-containing complex assembly#GO:0065003;protein-DNA complex assembly#GO:0065004;nucleobase-containing compound metabolic process#GO:0006139;reciprocal homologous recombination#GO:0140527;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;meiotic cell cycle process#GO:1903046;recombinational repair#GO:0000725;meiosis I cell cycle process#GO:0061982;reciprocal meiotic recombination#GO:0007131;reproductive process#GO:0022414;meiosis I#GO:0007127;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular component assembly#GO:0022607;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;meiotic cell cycle#GO:0051321;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;double-strand break repair via homologous recombination#GO:0000724;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;reproduction#GO:0000003;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;meiotic nuclear division#GO:0140013;sexual reproduction#GO:0019953;cell cycle#GO:0007049;organelle fission#GO:0048285;homologous recombination#GO:0035825;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;replication fork#GO:0005657;intracellular anatomical structure#GO:0005622 DNA metabolism protein#PC00009 CIOIN|Ensembl=ENSCING00000009527.3|UniProtKB=F6UXH9 F6UXH9 LOC100177747 PTHR11225:SF4 NUCLEAR PORE COMPLEX PROTEIN NUP93 NUCLEOPORIN NUP93 DEAD EYE PROTEIN NUCLEAR PORE COMPLEX PROTEIN NUP93 structural molecule activity#GO:0005198;structural constituent of nuclear pore#GO:0017056 cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;protein localization to nucleus#GO:0034504;nucleic acid transport#GO:0050657;nitrogen compound transport#GO:0071705;gene expression#GO:0010467;biosynthetic process#GO:0009058;establishment of protein localization#GO:0045184;RNA localization#GO:0006403;organic substance transport#GO:0071702;protein import into nucleus#GO:0006606;establishment of localization#GO:0051234;RNA transport#GO:0050658;protein localization to organelle#GO:0033365;nuclear transport#GO:0051169;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;poly(A)+ mRNA export from nucleus#GO:0016973;mRNA export from nucleus#GO:0006406;macromolecule biosynthetic process#GO:0009059;establishment of RNA localization#GO:0051236;macromolecule metabolic process#GO:0043170;establishment of protein localization to organelle#GO:0072594;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;mRNA transport#GO:0051028;cellular process#GO:0009987;protein localization#GO:0008104;localization#GO:0051179;cellular macromolecule localization#GO:0070727;nuclear export#GO:0051168;nucleocytoplasmic transport#GO:0006913;nucleobase-containing compound transport#GO:0015931;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;import into nucleus#GO:0051170 envelope#GO:0031975;nuclear pore#GO:0005643;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear envelope#GO:0005635;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;organelle envelope#GO:0031967;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transporter#PC00227 CIOIN|Ensembl=ENSCING00000019384.1|UniProtKB=H2XXR3 H2XXR3 PTHR10459:SF112 DNA LIGASE POLY [ADP-RIBOSE] POLYMERASE 1 transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;glycosyltransferase activity#GO:0016757;pentosyltransferase activity#GO:0016763;catalytic activity#GO:0003824 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;double-strand break repair#GO:0006302;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;post-translational protein modification#GO:0043687;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;response to stress#GO:0006950;nitrogen compound metabolic process#GO:0006807;cellular response to stress#GO:0033554;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259;metabolic process#GO:0008152 intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA metabolism protein#PC00009 FAS signaling pathway#P00020>PARP#P00600 CIOIN|Ensembl=ENSCING00000002057.3|UniProtKB=F6SUM0 F6SUM0 PTHR43206:SF1 AMINOTRANSFERASE 4-AMINOBUTYRATE AMINOTRANSFERASE, MITOCHONDRIAL transferase activity#GO:0016740;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;transaminase activity#GO:0008483;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167 oxoacid metabolic process#GO:0043436;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;amino acid catabolic process#GO:0009063;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;nitrogen compound metabolic process#GO:0006807;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;carboxylic acid metabolic process#GO:0019752;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transaminase#PC00216 Aminobutyrate degradation#P02726>4-aminobutyrate aminotransferase#P02825;Pyrimidine Metabolism#P02771>Aminotransferase#P03129;Gamma-aminobutyric acid synthesis#P04384>GABA aminotransferase#P04480 CIOIN|Ensembl=ENSCING00000014647.2|UniProtKB=F7BI62 F7BI62 PTHR45989:SF1 TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT GAMMA TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT GAMMA nucleoside-triphosphatase regulator activity#GO:0060589;nucleic acid binding#GO:0003676;translation regulator activity#GO:0045182;GTPase regulator activity#GO:0030695;binding#GO:0005488;organic cyclic compound binding#GO:0097159;molecular function regulator activity#GO:0098772;translation initiation factor activity#GO:0003743;translation regulator activity, nucleic acid binding#GO:0090079;enzyme regulator activity#GO:0030234;translation factor activity, RNA binding#GO:0008135;guanyl-nucleotide exchange factor activity#GO:0005085 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cytoplasmic translation#GO:0002181;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cytoplasmic translational initiation#GO:0002183;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;translational initiation#GO:0006413;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;guanyl-nucleotide exchange factor complex#GO:0032045;intracellular protein-containing complex#GO:0140535;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622 translation initiation factor#PC00224;translation factor#PC00223;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000006169.3|UniProtKB=F7BKT8 F7BKT8 LOC100178403 PTHR19876:SF2 COATOMER COATOMER SUBUNIT BETA' endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;intra-Golgi vesicle-mediated transport#GO:0006891;macromolecule localization#GO:0033036;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;coated vesicle#GO:0030135;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;vesicle coat#GO:0030120;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;Golgi-associated vesicle membrane#GO:0030660;protein-containing complex#GO:0032991;COPI vesicle coat#GO:0030126;endomembrane system#GO:0012505;membrane coat#GO:0030117;coated vesicle membrane#GO:0030662;COPI-coated vesicle#GO:0030137;Golgi-associated vesicle#GO:0005798;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;coated membrane#GO:0048475;cytoplasmic vesicle membrane#GO:0030659 vesicle coat protein#PC00235 CIOIN|Ensembl=ENSCING00000010042.3|UniProtKB=F6QHK4 F6QHK4 PTHR35245:SF2 FAMILY NOT NAMED DISINTEGRIN DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000011397.2|UniProtKB=A0A1W2WQI1 A0A1W2WQI1 LOC100183014 PTHR13068:SF112 CGI-12 PROTEIN-RELATED TRANSCRIPTION TERMINATION FACTOR 3, MITOCHONDRIAL CIOIN|Ensembl=ENSCING00000020187.1|UniProtKB=H2Y2N7 H2Y2N7 PTHR17125:SF2 OUTER DENSE FIBER PROTEIN 1 OUTER DENSE FIBER PROTEIN 1 CIOIN|Ensembl=ENSCING00000002766.3|UniProtKB=F7AH68 F7AH68 LOC100177184 PTHR24068:SF153 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 W ubiquitin-like protein conjugating enzyme activity#GO:0061650;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin conjugating enzyme activity#GO:0061631;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein polyubiquitination#GO:0000209;proteasomal protein catabolic process#GO:0010498;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000018135.1|UniProtKB=H2Y3D4 H2Y3D4 PTHR13826:SF14 INTESTINAL TREFOIL FACTOR-RELATED TREFOIL FACTOR 2 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 CIOIN|Ensembl=ENSCING00000011260.2|UniProtKB=F6YTC9 F6YTC9 PTHR31400:SF1 GUANYLYL CYCLASE DOMAIN CONTAINING PROTEIN 1 GUCD1 PROTEIN GUCD1 cyclase#PC00079;guanylate cyclase#PC00114;lyase#PC00144 CIOIN|Ensembl=ENSCING00000013858.2|UniProtKB=F6QGI1 F6QGI1 PTHR24246:SF27 OLFACTORY RECEPTOR AND ADENOSINE RECEPTOR ADENOSINE RECEPTOR, ISOFORM A G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711 CIOIN|Ensembl=ENSCING00000020209.1|UniProtKB=H2XV64 H2XV64 PTHR31912:SF34 IP13529P NOTOCHORD-RELATED PROTEIN CIOIN|Ensembl=ENSCING00000021867.1|UniProtKB=H2XY83 H2XY83 PTHR28641:SF1 FAMILY NOT NAMED MALONYL-COA DECARBOXYLASE, MITOCHONDRIAL CIOIN|Ensembl=ENSCING00000019658.1|UniProtKB=H2XTZ1 H2XTZ1 LOC100184986 PTHR11961:SF12 CYTOCHROME C CYTOCHROME C Apoptosis signaling pathway#P00006>Cytochrome C#P00322;ATP synthesis#P02721>Cyt C#P02798 CIOIN|Ensembl=ENSCING00000012236.2|UniProtKB=F6TL47 F6TL47 PTHR24300:SF397 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 2U1 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;tetrapyrrole binding#GO:0046906;steroid hydroxylase activity#GO:0008395;oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497;heme binding#GO:0020037 response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;response to chemical#GO:0042221;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 oxygenase#PC00177;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000014945.2|UniProtKB=F6VKL4 F6VKL4 LOC100178296 PTHR31214:SF3 PROTEIN FAM221A-RELATED PROTEIN FAM221B CIOIN|Ensembl=ENSCING00000003961.3|UniProtKB=Q8SSZ0 Q8SSZ0 Ci-PDEdelta PTHR12976:SF0 RETINAL ROD RHODOPSIN-SENSITIVE CGMP 3',5'-CYCLIC PHOSPHODIESTERASE DELTA-SUBUNIT RETINAL ROD RHODOPSIN-SENSITIVE CGMP 3',5'-CYCLIC PHOSPHODIESTERASE SUBUNIT DELTA cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 phosphodiesterase#PC00185 CIOIN|Ensembl=ENSCING00000004870.3|UniProtKB=A0A1W5BJR6 A0A1W5BJR6 LOC100181422 PTHR11669:SF5 REPLICATION FACTOR C / DNA POLYMERASE III GAMMA-TAU SUBUNIT REPLICATION FACTOR C SUBUNIT 2 ATP-dependent activity, acting on DNA#GO:0008094;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on DNA#GO:0140097;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;response to stress#GO:0006950;nitrogen compound metabolic process#GO:0006807;DNA-templated DNA replication#GO:0006261;DNA replication#GO:0006260;cellular response to stress#GO:0033554;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;replication fork#GO:0005657 DNA-directed DNA polymerase#PC00018 DNA replication#P00017>RFC#P00529 CIOIN|Ensembl=ENSCING00000019352.1|UniProtKB=H2XWV5 H2XWV5 PTHR46188:SF1 BOLA-LIKE PROTEIN 3 BOLA-LIKE PROTEIN 3 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000015283.2|UniProtKB=F6TY79 F6TY79 LOC100186620 PTHR24064:SF577 SOLUTE CARRIER FAMILY 22 MEMBER GH09241P secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000001976.3|UniProtKB=F6X3R5 F6X3R5 PTHR11607:SF3 ALPHA-MANNOSIDASE LYSOSOMAL ALPHA-MANNOSIDASE hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 glycosidase#PC00110;metabolite interconversion enzyme#PC00262;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000002875.3|UniProtKB=F6T0X5 F6T0X5 LOC100178020 PTHR21351:SF0 BARDET-BIEDL SYNDROME PROTEIN 5 BARDET-BIEDL SYNDROME 5 PROTEIN phosphatidylinositol-3-phosphate binding#GO:0032266;lipid binding#GO:0008289;phosphatidylinositol binding#GO:0035091;phospholipid binding#GO:0005543;phosphatidylinositol phosphate binding#GO:1901981;binding#GO:0005488 cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;cilium assembly#GO:0060271;cell projection organization#GO:0030030;transport#GO:0006810;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;organelle organization#GO:0006996;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031 microtubule organizing center#GO:0005815;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;ciliary basal body#GO:0036064;membrane-bounded organelle#GO:0043227;BBSome#GO:0034464;cytoskeleton#GO:0005856;cell projection#GO:0042995;cilium#GO:0005929 CIOIN|Ensembl=ENSCING00000005712.3|UniProtKB=F6WPG2 F6WPG2 PTHR42884:SF13 PROPROTEIN CONVERTASE SUBTILISIN/KEXIN-RELATED NEUROENDOCRINE CONVERTASE 2 hydrolase activity#GO:0016787;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;regulation of hormone levels#GO:0010817;cellular process#GO:0009987;protein processing#GO:0016485;primary metabolic process#GO:0044238;hormone metabolic process#GO:0042445;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;biological regulation#GO:0065007;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 bounding membrane of organelle#GO:0098588;trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231;extracellular region#GO:0005576;Golgi apparatus#GO:0005794;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;neuron projection#GO:0043005;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791;cell projection#GO:0042995;Golgi membrane#GO:0000139 serine protease#PC00203;protein modifying enzyme#PC00260 Alzheimer disease-presenilin pathway#P00004>Furin#P00157;Alzheimer disease-amyloid secretase pathway#P00003>Furin#P00105 CIOIN|Ensembl=ENSCING00000007391.3|UniProtKB=Q8T883 Q8T883 Ci-tektinB1 PTHR19960:SF7 TEKTIN TEKTIN cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cell projection organization#GO:0030030;microtubule-based movement#GO:0007018;cilium or flagellum-dependent cell motility#GO:0001539;cell motility#GO:0048870;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031;cilium movement involved in cell motility#GO:0060294;cilium movement#GO:0003341;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cilium-dependent cell motility#GO:0060285;microtubule-based process#GO:0007017;organelle organization#GO:0006996;plasma membrane bounded cell projection assembly#GO:0120031 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 CIOIN|Ensembl=ENSCING00000008937.4|UniProtKB=F6Q9P9 F6Q9P9 PTHR10745:SF0 GLYCYL-TRNA SYNTHETASE/DNA POLYMERASE SUBUNIT GAMMA-2 GLYCINE--TRNA LIGASE catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;ligase activity#GO:0016874;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;peptide biosynthetic process#GO:0043043;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 aminoacyl-tRNA synthetase#PC00047;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000019963.1|UniProtKB=H2Y1C5 H2Y1C5 PTHR11662:SF399 SOLUTE CARRIER FAMILY 17 FI19708P1-RELATED secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000000046.3|UniProtKB=F6ZIL3 F6ZIL3 PTHR18945:SF916 NEUROTRANSMITTER GATED ION CHANNEL GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT BETA-LIKE inorganic molecular entity transmembrane transporter activity#GO:0015318;signaling receptor activity#GO:0038023;chloride channel activity#GO:0005254;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;molecular transducer activity#GO:0060089;chloride transmembrane transporter activity#GO:0015108;monoatomic anion transmembrane transporter activity#GO:0008509;inorganic anion transmembrane transporter activity#GO:0015103;transporter activity#GO:0005215;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267;transmembrane signaling receptor activity#GO:0004888 ligand-gated ion channel#PC00141;ion channel#PC00133;transporter#PC00227 CIOIN|Ensembl=ENSCING00000018600.1|UniProtKB=H2XL81 H2XL81 PTHR12630:SF6 N-LINKED OLIGOSACCHARIDE PROCESSING N-ACETYLGLUCOSAMINE-1-PHOSPHOTRANSFERASE SUBUNIT GAMMA carbohydrate derivative metabolic process#GO:1901135;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;endoplasmic reticulum protein-containing complex#GO:0140534;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;catalytic complex#GO:1902494;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein-binding activity modulator#PC00095 CIOIN|Ensembl=ENSCING00000011803.2|UniProtKB=F6S0A3 F6S0A3 LOC100183736 PTHR32073:SF7 GH11358P GH11358P CIOIN|Ensembl=ENSCING00000006319.3|UniProtKB=F6Q476 F6Q476 PTHR16151:SF2 HAUS AUGMIN-LIKE COMPLEX SUBUNIT 6 HAUS AUGMIN-LIKE COMPLEX SUBUNIT 6 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cellular process#GO:0009987;microtubule-based process#GO:0007017;organelle organization#GO:0006996 supramolecular complex#GO:0099080;spindle microtubule#GO:0005876;cellular anatomical entity#GO:0110165;supramolecular fiber#GO:0099512;supramolecular polymer#GO:0099081;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;mitotic spindle#GO:0072686;microtubule cytoskeleton#GO:0015630;cytoskeleton#GO:0005856;spindle#GO:0005819;microtubule#GO:0005874 CIOIN|Ensembl=ENSCING00000017324.2|UniProtKB=F6XQ94 F6XQ94 PTHR16219:SF1 AUGMIN SUBUNIT 4 FAMILY MEMBER HAUS AUGMIN-LIKE COMPLEX SUBUNIT 4 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;cellular component organization#GO:0016043;cellular process#GO:0009987;chromosome segregation#GO:0007059;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;spindle assembly#GO:0051225;cytoskeleton organization#GO:0007010;cell cycle#GO:0007049;spindle organization#GO:0007051;non-membrane-bounded organelle assembly#GO:0140694 intracellular non-membrane-bounded organelle#GO:0043232;microtubule associated complex#GO:0005875;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;HAUS complex#GO:0070652;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000001452.3|UniProtKB=F6VL41 F6VL41 PTHR24078:SF519 DNAJ HOMOLOG SUBFAMILY C MEMBER DNAJ HOMOLOG SUBFAMILY B MEMBER 13 protein binding#GO:0005515;protein-folding chaperone binding#GO:0051087;unfolded protein binding#GO:0051082;binding#GO:0005488 macromolecule biosynthetic process#GO:0009059;chaperone-mediated protein folding#GO:0061077;chaperone cofactor-dependent protein refolding#GO:0051085;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein folding#GO:0006457;'de novo' protein folding#GO:0006458;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 chaperone#PC00072 CIOIN|Ensembl=ENSCING00000007866.3|UniProtKB=F6THC9 F6THC9 PTHR43842:SF2 PROPIONYL-COA CARBOXYLASE BETA CHAIN PROPIONYL-COA CARBOXYLASE BETA CHAIN, MITOCHONDRIAL ligase activity#GO:0016874;catalytic activity#GO:0003824 metabolite interconversion enzyme#PC00262;ligase#PC00142 Methylmalonyl pathway#P02755>Propionyl-CoA carboxylase#P03033;Succinate to proprionate conversion#P02777>Methylmalonyl-CoA decarboxylase#P03163 CIOIN|Ensembl=ENSCING00000013458.2|UniProtKB=F6V2B2 F6V2B2 PTHR11953:SF2 EXOSOME COMPLEX COMPONENT EXOSOME COMPLEX COMPONENT MTR3 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;heterocycle catabolic process#GO:0046700;RNA metabolic process#GO:0016070;RNA processing#GO:0006396;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;cellular nitrogen compound catabolic process#GO:0044270;regulation of biological process#GO:0050789;ncRNA metabolic process#GO:0034660;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;mRNA catabolic process#GO:0006402;snRNA 3'-end processing#GO:0034472;catabolic process#GO:0009056;snRNA processing#GO:0016180;RNA catabolic process#GO:0006401;regulation of macromolecule biosynthetic process#GO:0010556;organic substance catabolic process#GO:1901575;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;snRNA metabolic process#GO:0016073;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;negative regulation of metabolic process#GO:0009892;nuclear-transcribed mRNA catabolic process#GO:0000956;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;aromatic compound catabolic process#GO:0019439;regulation of macromolecule metabolic process#GO:0060255;rRNA metabolic process#GO:0016072;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;nucleobase-containing compound catabolic process#GO:0034655;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;exosome (RNase complex)#GO:0000178;nuclear protein-containing complex#GO:0140513 RNA metabolism protein#PC00031;exoribonuclease#PC00099 CIOIN|Ensembl=ENSCING00000008145.3|UniProtKB=F6VG23 F6VG23 LOC100184175 PTHR13132:SF29 ALPHA- 1,6 -FUCOSYLTRANSFERASE ALPHA-(1,6)-FUCOSYLTRANSFERASE transferase activity#GO:0016740;fucosyltransferase activity#GO:0008417;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein glycosylation#GO:0006486;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein N-linked glycosylation#GO:0006487;protein metabolic process#GO:0019538;glycosylation#GO:0070085;glycoprotein metabolic process#GO:0009100;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 glycosyltransferase#PC00111 Notch signaling pathway#P00045>Neurotic#P01115 CIOIN|Ensembl=ENSCING00000022149.1|UniProtKB=H2XUW3 H2XUW3 LOC494405 PTHR31353:SF1 FAM98 PROTEIN FAM98B RNA splicing factor#PC00148;RNA processing factor#PC00147 CIOIN|Ensembl=ENSCING00000002767.3|UniProtKB=F7AH61 F7AH61 PTHR11264:SF0 URACIL-DNA GLYCOSYLASE URACIL-DNA GLYCOSYLASE catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;catalytic activity, acting on DNA#GO:0140097;DNA N-glycosylase activity#GO:0019104;catalytic activity#GO:0003824 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;base-excision repair#GO:0006284;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;DNA damage response#GO:0006974;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 DNA glycosylase#PC00010 CIOIN|Ensembl=ENSCING00000005021.3|UniProtKB=F6TXK6 F6TXK6 PTHR10985:SF77 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, HES-RELATED GH26014P sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of multicellular organismal process#GO:0051239;regulation of cell development#GO:0060284;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regionalization#GO:0003002;developmental process#GO:0032502;multicellular organism development#GO:0007275;regulation of RNA biosynthetic process#GO:2001141;regulation of multicellular organismal development#GO:2000026;regulation of cell differentiation#GO:0045595;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of neurogenesis#GO:0050767;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;regulation of nervous system development#GO:0051960;biological regulation#GO:0065007;anterior/posterior pattern specification#GO:0009952;multicellular organismal process#GO:0032501;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;pattern specification process#GO:0007389;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;basic helix-loop-helix transcription factor#PC00055 CIOIN|Ensembl=ENSCING00000014835.2|UniProtKB=F7BGT4 F7BGT4 PTHR11254:SF429 HECT DOMAIN UBIQUITIN-PROTEIN LIGASE E3 UBIQUITIN-PROTEIN LIGASE SU(DX) transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234 CIOIN|Ensembl=ENSCING00000021944.1|UniProtKB=H2XMX0 H2XMX0 PTHR46139:SF3 ALKALINE CERAMIDASE ALKALINE CERAMIDASE lipid metabolic process#GO:0006629;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;lipid catabolic process#GO:0016042;cellular process#GO:0009987;sphingolipid metabolic process#GO:0006665;ceramide metabolic process#GO:0006672;primary metabolic process#GO:0044238;membrane lipid metabolic process#GO:0006643;nitrogen compound metabolic process#GO:0006807;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;cellular lipid metabolic process#GO:0044255;sphingolipid catabolic process#GO:0030149;amide metabolic process#GO:0043603;cellular lipid catabolic process#GO:0044242;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 CIOIN|Ensembl=ENSCING00000021744.1|UniProtKB=H2XX93 H2XX93 PTHR13906:SF12 PORCUPINE PROTEIN-SERINE O-PALMITOLEOYLTRANSFERASE PORCUPINE protein binding#GO:0005515;transferase activity#GO:0016740;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;Wnt-protein binding#GO:0017147;binding#GO:0005488;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;cellular localization#GO:0051641;macromolecule localization#GO:0033036;macromolecule modification#GO:0043412;transport#GO:0006810;nitrogen compound transport#GO:0071705;protein modification process#GO:0036211;protein secretion#GO:0009306;lipid modification#GO:0030258;biosynthetic process#GO:0009058;establishment of protein localization#GO:0045184;regulation of biological process#GO:0050789;organic substance transport#GO:0071702;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;secretion#GO:0046903;signal release#GO:0023061;protein palmitoylation#GO:0018345;protein metabolic process#GO:0019538;protein lipidation#GO:0006497;cell-cell signaling#GO:0007267;signaling#GO:0023052;organic substance metabolic process#GO:0071704;secretion by cell#GO:0032940;metabolic process#GO:0008152;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cell communication#GO:0007154;organic substance biosynthetic process#GO:1901576;protein acylation#GO:0043543;cell-cell signaling by wnt#GO:0198738;cellular process#GO:0009987;lipoprotein biosynthetic process#GO:0042158;primary metabolic process#GO:0044238;protein localization#GO:0008104;localization#GO:0051179;establishment of protein localization to extracellular region#GO:0035592;cellular macromolecule localization#GO:0070727;protein transport#GO:0015031;biological regulation#GO:0065007;lipoprotein metabolic process#GO:0042157;cellular lipid metabolic process#GO:0044255;protein localization to extracellular region#GO:0071692;export from cell#GO:0140352 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 acetyltransferase#PC00038;transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000011709.2|UniProtKB=F6WLH1 F6WLH1 PTHR43651:SF3 1,4-ALPHA-GLUCAN-BRANCHING ENZYME 1,4-ALPHA-GLUCAN-BRANCHING ENZYME transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 carbohydrate metabolic process#GO:0005975;organic substance metabolic process#GO:0071704;primary metabolic process#GO:0044238;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 amylase#PC00048;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000008604.3|UniProtKB=F6TPC0 F6TPC0 LOC104265579 PTHR12121:SF37 CARBON CATABOLITE REPRESSOR PROTEIN 4 2',5'-PHOSPHODIESTERASE 12 catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;catalytic activity#GO:0003824;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters#GO:0016796;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity#GO:0016787;3'-5'-RNA exonuclease activity#GO:0000175;3'-5' exonuclease activity#GO:0008408;exonuclease activity#GO:0004527;RNA nuclease activity#GO:0004540 negative regulation of gene expression#GO:0010629;regulation of catabolic process#GO:0009894;heterocycle catabolic process#GO:0046700;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;nucleobase-containing compound metabolic process#GO:0006139;RNA destabilization#GO:0050779;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;regulation of RNA stability#GO:0043487;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;positive regulation of mRNA catabolic process#GO:0061014;regulation of cellular process#GO:0050794;post-transcriptional regulation of gene expression#GO:0010608;positive regulation of catabolic process#GO:0009896;mRNA destabilization#GO:0061157;nucleobase-containing compound catabolic process#GO:0034655;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;regulation of mRNA stability#GO:0043488;RNA metabolic process#GO:0016070;positive regulation of cellular catabolic process#GO:0031331;cellular nitrogen compound catabolic process#GO:0044270;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;mRNA catabolic process#GO:0006402;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;regulation of gene expression#GO:0010468;organic substance catabolic process#GO:1901575;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;positive regulation of mRNA metabolic process#GO:1903313;heterocycle metabolic process#GO:0046483;negative regulation of biosynthetic process#GO:0009890;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;positive regulation of RNA metabolic process#GO:0051254 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 mRNA polyadenylation factor#PC00146 CIOIN|Ensembl=ENSCING00000013251.2|UniProtKB=F6XKJ1 F6XKJ1 PTHR43975:SF2 ZGC:101858 EG:BACR7A4.14 PROTEIN-RELATED CIOIN|Ensembl=ENSCING00000002663.3|UniProtKB=F6YD53 F6YD53 PTHR43150:SF2 HYPERKINETIC, ISOFORM M HYPERKINETIC, ISOFORM M CIOIN|Ensembl=ENSCING00000024664.1|UniProtKB=H2XJK0 H2XJK0 PTHR10682:SF10 POLY A POLYMERASE POLYNUCLEOTIDE ADENYLYLTRANSFERASE adenylyltransferase activity#GO:0070566;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;RNA processing#GO:0006396;mRNA polyadenylation#GO:0006378;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;mRNA 3'-end processing#GO:0031124;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;mRNA processing#GO:0006397;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 mRNA polyadenylation factor#PC00146;RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000016915.2|UniProtKB=F6Q349 F6Q349 LOC100182890 PTHR24070:SF406 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY SMALL MONOMERIC GTPASE GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;ion binding#GO:0043167;anion binding#GO:0043168 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 small GTPase#PC00208;G-protein#PC00020 Integrin signalling pathway#P00034>Rap1#P00906 CIOIN|Ensembl=ENSCING00000001811.3|UniProtKB=F6X593 F6X593 LOC100186319 PTHR43735:SF3 APOPTOSIS-INDUCING FACTOR 1 FERROPTOSIS SUPPRESSOR PROTEIN 1 nucleotide binding#GO:0000166;electron transfer activity#GO:0009055;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;flavin adenine dinucleotide binding#GO:0050660;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167;oxidoreductase activity#GO:0016491 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 p53 pathway#P00059>NOXA#G01572 CIOIN|Ensembl=ENSCING00000003145.3|UniProtKB=Q7YT82 Q7YT82 rhoc PTHR24072:SF168 RHO FAMILY GTPASE RAS-LIKE GTP-BINDING PROTEIN RHO1 GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;enzyme binding#GO:0019899;ribonucleoside triphosphate phosphatase activity#GO:0017111;kinase binding#GO:0019900;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;protein kinase binding#GO:0019901;anion binding#GO:0043168;ion binding#GO:0043167 regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;regulation of cellular process#GO:0050794;regulation of organelle organization#GO:0033043;regulation of actin cytoskeleton organization#GO:0032956;biological regulation#GO:0065007;regulation of actin filament-based process#GO:0032970;regulation of cellular component organization#GO:0051128 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 small GTPase#PC00208 Ras Pathway#P04393>Rho#P04578;Integrin signalling pathway#P00034>Rho#P00948;Angiogenesis#P00005>GTPase#P00254;Axon guidance mediated by Slit/Robo#P00008>Rho#P00355;Cytoskeletal regulation by Rho GTPase#P00016>Rho#P00507 CIOIN|Ensembl=ENSCING00000004238.3|UniProtKB=F6YGF2 F6YGF2 LOC100176454 PTHR43669:SF3 5-KETO-D-GLUCONATE 5-REDUCTASE ALCOHOL DEHYDROGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G03445)-RELATED oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000015178.2|UniProtKB=F6XY77 F6XY77 PTHR46830:SF1 TRANSFERASE, PUTATIVE-RELATED ALPHA-1,4-N-ACETYLGLUCOSAMINYLTRANSFERASE transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000005614.3|UniProtKB=F7ATG5 F7ATG5 PTHR44321:SF1 TRANSDUCIN BETA-LIKE PROTEIN 2 TRANSDUCIN BETA-LIKE PROTEIN 2 response to organic substance#GO:0010033;signal transduction#GO:0007165;endoplasmic reticulum unfolded protein response#GO:0030968;cellular response to stimulus#GO:0051716;response to endoplasmic reticulum stress#GO:0034976;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to topologically incorrect protein#GO:0035967;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;response to topologically incorrect protein#GO:0035966;response to unfolded protein#GO:0006986;cellular response to unfolded protein#GO:0034620;biological regulation#GO:0065007;cellular response to stress#GO:0033554;signaling#GO:0023052 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000009122.3|UniProtKB=F6S3Q7 F6S3Q7 PTHR12640:SF0 RIBOPHORIN II DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT 2 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein N-linked glycosylation#GO:0006487;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 membrane protein complex#GO:0098796;endoplasmic reticulum protein-containing complex#GO:0140534;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endoplasmic reticulum subcompartment#GO:0098827;oligosaccharyltransferase complex#GO:0008250;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 glycosyltransferase#PC00111 CIOIN|Ensembl=ENSCING00000006789.3|UniProtKB=F6VE75 F6VE75 PTHR13609:SF4 UBIQUITIN DOMAIN CONTAINING 1 PROTEIN-RELATED RE42193P ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000022395.1|UniProtKB=H2XZY8 H2XZY8 PTHR21540:SF3 RING FINGER AND SWIM DOMAIN-CONTAINING PROTEIN 2 E3 UBIQUITIN-PROTEIN LIGASE ZSWIM2 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000009395.3|UniProtKB=F6U9X5 F6U9X5 LOC100186345 PTHR23105:SF1 RIBOSOMAL PROTEIN L7AE FAMILY MEMBER LARGE RIBOSOMAL SUBUNIT PROTEIN EL8 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;ribosomal large subunit biogenesis#GO:0042273;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;maturation of LSU-rRNA#GO:0000470;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic large ribosomal subunit#GO:0022625;large ribosomal subunit#GO:0015934;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202 CIOIN|Ensembl=ENSCING00000000599.3|UniProtKB=F6U1X0 F6U1X0 LOC100183999 PTHR11552:SF147 GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE CHOLINE DEHYDROGENASE, MITOCHONDRIAL oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000020776.1|UniProtKB=H2Y2U3 H2Y2U3 PTHR21681:SF0 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT J EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT J cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical entity#GO:0110165;eukaryotic translation initiation factor 3 complex#GO:0005852;intracellular anatomical structure#GO:0005622 translation initiation factor#PC00224;translation factor#PC00223;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000002369.3|UniProtKB=F6R501 F6R501 LOC100176681 PTHR13866:SF31 SPARC OSTEONECTIN SPARC-LIKE 2 cation binding#GO:0043169;extracellular matrix binding#GO:0050840;small molecule binding#GO:0036094;binding#GO:0005488;collagen binding#GO:0005518;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;protein-containing complex binding#GO:0044877;ion binding#GO:0043167 anatomical structure development#GO:0048856;developmental process#GO:0032502 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 extracellular matrix glycoprotein#PC00100 CIOIN|Ensembl=ENSCING00000012588.2|UniProtKB=F6Y3X0 F6Y3X0 LOC100182246 PTHR12790:SF0 TRANSCRIPTION INITIATION FACTOR IA RRN3 RNA POLYMERASE I-SPECIFIC TRANSCRIPTION INITIATION FACTOR RRN3-RELATED enzyme binding#GO:0019899;protein binding#GO:0005515;RNA polymerase binding#GO:0070063;binding#GO:0005488;RNA polymerase core enzyme binding#GO:0043175 cellular aromatic compound metabolic process#GO:0006725;DNA-templated transcription#GO:0006351;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;RNA biosynthetic process#GO:0032774;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleic acid metabolic process#GO:0090304;transcription by RNA polymerase I#GO:0006360;organic cyclic compound metabolic process#GO:1901360;nucleobase-containing compound biosynthetic process#GO:0034654;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;DNA-templated transcription initiation#GO:0006352;aromatic compound biosynthetic process#GO:0019438;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031;general transcription factor#PC00259 General transcription by RNA polymerase I#P00022>RNA Polymerase I Complex#P00652 CIOIN|Ensembl=ENSCING00000022449.1|UniProtKB=H2XZM0 H2XZM0 LOC100179612 PTHR10098:SF108 RAPSYN-RELATED TETRATRICOPEPTIDE REPEAT PROTEIN 28 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000004980.3|UniProtKB=F6WMK2 F6WMK2 PTHR11630:SF47 DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER DNA HELICASE MCM8 ATP-dependent activity, acting on DNA#GO:0008094;nucleic acid binding#GO:0003676;helicase activity#GO:0004386;ATP-dependent activity#GO:0140657;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;single-stranded DNA binding#GO:0003697;DNA binding#GO:0003677;catalytic activity, acting on a nucleic acid#GO:0140640;DNA helicase activity#GO:0003678;single-stranded DNA helicase activity#GO:0017116;catalytic activity, acting on DNA#GO:0140097 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;MCM complex#GO:0042555;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA metabolism protein#PC00009 CIOIN|Ensembl=ENSCING00000001821.3|UniProtKB=Q9NL43 Q9NL43 CiGSK PTHR24057:SF0 GLYCOGEN SYNTHASE KINASE-3 ALPHA PROTEIN KINASE SHAGGY-RELATED transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;developmental process#GO:0032502;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cell differentiation#GO:0030154;peptidyl-threonine phosphorylation#GO:0018107;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 Wnt signaling pathway#P00057>Glycogen Synthase Kinase-3Beta#P01441;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>GSK-3#P00902;PI3 kinase pathway#P00048>GSK3#P01181;Interleukin signaling pathway#P00036>GSK3#P00976;Ras Pathway#P04393>GSK3#P04546;Angiogenesis#P00005>GSK3beta#P00211;Alzheimer disease-presenilin pathway#P00004>GSK-3beta#P00175;PDGF signaling pathway#P00047>GSK3#P01153 CIOIN|Ensembl=ENSCING00000005600.3|UniProtKB=F6TFE2 F6TFE2 PTHR12734:SF0 METHYLTRANSFERASE-RELATED 18S RRNA (GUANINE-N(7))-METHYLTRANSFERASE-RELATED catalytic activity, acting on RNA#GO:0140098;transferase activity#GO:0016740;catalytic activity#GO:0003824;rRNA (guanine) methyltransferase activity#GO:0016435;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on a rRNA#GO:0140102;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;rRNA methyltransferase activity#GO:0008649;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;RNA methyltransferase activity#GO:0008173 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;RNA modification#GO:0009451;rRNA modification#GO:0000154;RNA processing#GO:0006396;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;ribosome biogenesis#GO:0042254;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;rRNA methylation#GO:0031167;nucleic acid metabolic process#GO:0090304;methylation#GO:0032259;macromolecule methylation#GO:0043414;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;rRNA base methylation#GO:0070475;RNA methylation#GO:0001510 intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 methyltransferase#PC00155;transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000004907.3|UniProtKB=F7B991 F7B991 LOC100178929 PTHR45619:SF8 SERINE/THREONINE-PROTEIN PHOSPHATASE PP2A-RELATED SERINE_THREONINE-PROTEIN PHOSPHATASE 4 CATALYTIC SUBUNIT hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;protein serine/threonine phosphatase activity#GO:0004722;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;double-strand break repair via homologous recombination#GO:0000724;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;response to stress#GO:0006950;nitrogen compound metabolic process#GO:0006807;recombinational repair#GO:0000725;cellular response to stress#GO:0033554;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein phosphatase#PC00195;protein modifying enzyme#PC00260 EGF receptor signaling pathway#P00018>PP2A#P00547;FGF signaling pathway#P00021>PP2A#P00629 CIOIN|Ensembl=ENSCING00000005981.3|UniProtKB=F6VT16 F6VT16 PTHR13096:SF7 MINA53 MYC INDUCED NUCLEAR ANTIGEN RIBOSOMAL OXYGENASE 2 histone modifying activity#GO:0140993;demethylase activity#GO:0032451;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;histone demethylase activity#GO:0032452;catalytic activity#GO:0003824;dioxygenase activity#GO:0051213;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491 membrane-enclosed lumen#GO:0031974;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000024060.1|UniProtKB=F6PMP3 F6PMP3 PTHR10127:SF814 DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING MEPRIN A SUBUNIT BETA hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000001243.3|UniProtKB=F7AES2 F7AES2 LOC100176930 PTHR11362:SF133 PHOSPHATIDYLETHANOLAMINE-BINDING PROTEIN LARGE RIBOSOMAL SUBUNIT PROTEIN ML38 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;mitochondrial large ribosomal subunit#GO:0005762;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;mitochondrial ribosome#GO:0005761;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;ribosomal subunit#GO:0044391;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;organellar ribosome#GO:0000313;protein-containing complex#GO:0032991;large ribosomal subunit#GO:0015934;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;ribosome#GO:0005840;mitochondrial protein-containing complex#GO:0098798 protease inhibitor#PC00191 CIOIN|Ensembl=ENSCING00000012291.2|UniProtKB=F7BEK9 F7BEK9 LOC100179397 PTHR43975:SF2 ZGC:101858 EG:BACR7A4.14 PROTEIN-RELATED CIOIN|Ensembl=ENSCING00000013557.2|UniProtKB=F6SW20 F6SW20 PTHR10454:SF210 CASPASE CASPASE-2 protease#PC00190;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000002832.3|UniProtKB=F7AJS0 F7AJS0 zf(ring)-23 PTHR23328:SF0 RING-TYPE DOMAIN-CONTAINING PROTEIN RING-TYPE DOMAIN-CONTAINING PROTEIN nucleosome binding#GO:0031491;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;chromatin binding#GO:0003682;protein-containing complex binding#GO:0044877;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;DNA damage response#GO:0006974;response to stress#GO:0006950;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular response to stress#GO:0033554;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;site of DNA damage#GO:0090734;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;site of double-strand break#GO:0035861;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000019818.1|UniProtKB=H2Y0S8 H2Y0S8 PTHR13456:SF0 UPF0729 PROTEIN C18ORF32 UPF0729 PROTEIN C18ORF32 CIOIN|Ensembl=ENSCING00000004257.3|UniProtKB=F6YFU4 F6YFU4 LOC100179935 PTHR45897:SF4 HIGH-AFFINITY CHOLINE TRANSPORTER 1 HIGH-AFFINITY CHOLINE TRANSPORTER 1 inorganic molecular entity transmembrane transporter activity#GO:0015318;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;sodium ion transmembrane transporter activity#GO:0015081;organic cation transmembrane transporter activity#GO:0015101;metal ion transmembrane transporter activity#GO:0046873;active monoatomic ion transmembrane transporter activity#GO:0022853;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;inorganic cation transmembrane transporter activity#GO:0022890;active transmembrane transporter activity#GO:0022804;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transporter#PC00227 Nicotinic acetylcholine receptor signaling pathway#P00044>CHT1#P01098;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>CHT1#P01084;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>CHT1#P01072 CIOIN|Ensembl=ENSCING00000007981.3|UniProtKB=F6WR70 F6WR70 PTHR18849:SF8 LEUCINE RICH REPEAT PROTEIN LEUCINE-RICH REPEAT-CONTAINING PROTEIN 61 cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;outer dynein arm assembly#GO:0036158;cell projection organization#GO:0030030;protein-containing complex assembly#GO:0065003;microtubule cytoskeleton organization#GO:0000226;cellular component organization#GO:0016043;axoneme assembly#GO:0035082;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;microtubule bundle formation#GO:0001578;axonemal dynein complex assembly#GO:0070286;cytoskeleton organization#GO:0007010;plasma membrane bounded cell projection assembly#GO:0120031 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000005851.3|UniProtKB=F6UGA6 F6UGA6 LOC100179723 PTHR10766:SF111 TRANSMEMBRANE 9 SUPERFAMILY PROTEIN TRANSMEMBRANE 9 SUPERFAMILY MEMBER 2 localization#GO:0051179;localization within membrane#GO:0051668;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;protein localization to membrane#GO:0072657;cellular process#GO:0009987;protein localization#GO:0008104 cellular anatomical entity#GO:0110165;membrane#GO:0016020 transporter#PC00227 CIOIN|Ensembl=ENSCING00000016443.2|UniProtKB=A0A1W2WPE0 A0A1W2WPE0 LOC100180325 PTHR22776:SF49 MARVEL-CONTAINING POTENTIAL LIPID RAFT-ASSOCIATED PROTEIN MARVEL DOMAIN-CONTAINING PROTEIN cellular anatomical entity#GO:0110165;membrane#GO:0016020 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000009380.3|UniProtKB=F6WX88 F6WX88 PTHR11616:SF182 SODIUM/CHLORIDE DEPENDENT TRANSPORTER TRANSPORTER metal ion transport#GO:0030001;transmembrane transport#GO:0055085;amino acid transport#GO:0006865;organic anion transport#GO:0015711;organic acid transport#GO:0015849;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;localization#GO:0051179;organic substance transport#GO:0071702;sodium ion transport#GO:0006814;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;sodium ion transmembrane transport#GO:0035725 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 primary active transporter#PC00068;transporter#PC00227 Adrenaline and noradrenaline biosynthesis#P00001>amine translocator#P00068 CIOIN|Ensembl=ENSCING00000025038.1|UniProtKB=H2XXD3 H2XXD3 PTHR24353:SF37 CYCLIC NUCLEOTIDE-DEPENDENT PROTEIN KINASE CAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT PRKX transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 serine/threonine protein kinase complex#GO:1902554;protein kinase complex#GO:1902911;intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;transferase complex#GO:1990234;transferase complex, transferring phosphorus-containing groups#GO:0061695 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Metabotropic glutamate receptor group III pathway#P00039>PKA#P01035;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>PKA#P01075;GABA-B receptor II signaling#P05731>PKA#P05752;5HT1 type receptor mediated signaling pathway#P04373>PKA#P04403;Enkephalin release#P05913>PKA#P05972;Histamine H2 receptor mediated signaling pathway#P04386>PKA#P04491;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PKA#P00862;Dopamine receptor mediated signaling pathway#P05912>PKA#P05946;Beta2 adrenergic receptor signaling pathway#P04378>PKA#P04444;Metabotropic glutamate receptor group II pathway#P00040>PKA#P01050;Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>PKA#P00746;Endothelin signaling pathway#P00019>PKG#P00567;Beta1 adrenergic receptor signaling pathway#P04377>PKA#P04437;Endothelin signaling pathway#P00019>PKA#P00570;Metabotropic glutamate receptor group I pathway#P00041>PKA#P01059 CIOIN|Ensembl=ENSCING00000024581.1|UniProtKB=H2XXZ8 H2XXZ8 LOC100176873 PTHR21212:SF0 BERNARDINELLI-SEIP CONGENITAL LIPODYSTROPHY 2 HOMOLOG BSCL2 PROTEIN SEIPIN localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;macromolecule localization#GO:0033036;maintenance of location#GO:0051235;organelle organization#GO:0006996;cellular component organization#GO:0016043;lipid localization#GO:0010876;lipid storage#GO:0019915;cellular process#GO:0009987 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000019618.1|UniProtKB=H2XY79 H2XY79 PTHR24372:SF77 GLYCOPROTEIN HORMONE RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 response to organic substance#GO:0010033;positive regulation of adenylate cyclase activity#GO:0045762;regulation of lyase activity#GO:0051339;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;cellular response to stimulus#GO:0051716;regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;cellular response to endogenous stimulus#GO:0071495;cellular response to chemical stimulus#GO:0070887;positive regulation of catalytic activity#GO:0043085;cellular response to organic substance#GO:0071310;regulation of cyclase activity#GO:0031279;positive regulation of molecular function#GO:0044093;cell communication#GO:0007154;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;positive regulation of cyclase activity#GO:0031281;hormone-mediated signaling pathway#GO:0009755;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to endogenous stimulus#GO:0009719;response to hormone#GO:0009725;cellular response to hormone stimulus#GO:0032870;response to chemical#GO:0042221;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of lyase activity#GO:0051349;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 CIOIN|Ensembl=ENSCING00000005745.3|UniProtKB=F6SXZ3 F6SXZ3 PTHR32308:SF0 LYASE BETA SUBUNIT, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G13030)-RELATED HPCH_HPAI ALDOLASE_CITRATE LYASE DOMAIN-CONTAINING PROTEIN cation binding#GO:0043169;metal ion binding#GO:0046872;magnesium ion binding#GO:0000287;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488 oxoacid metabolic process#GO:0043436;dicarboxylic acid metabolic process#GO:0043648;cellular metabolic process#GO:0044237;cellular process#GO:0009987;carboxylic acid metabolic process#GO:0019752;organic acid metabolic process#GO:0006082;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 lyase#PC00144 Pyruvate metabolism#P02772>Citrate Lyase#P03137 CIOIN|Ensembl=ENSCING00000018719.1|UniProtKB=H2XXM0 H2XXM0 PTHR24096:SF149 LONG-CHAIN-FATTY-ACID--COA LIGASE AMP-BINDING DOMAIN-CONTAINING PROTEIN-RELATED ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877 metabolite interconversion enzyme#PC00262;ligase#PC00142 CIOIN|Ensembl=ENSCING00000007085.3|UniProtKB=F6W9F7 F6W9F7 PTHR10334:SF554 CYSTEINE-RICH SECRETORY PROTEIN-RELATED AT04879P-RELATED extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 defense/immunity protein#PC00090 CIOIN|Ensembl=ENSCING00000006512.3|UniProtKB=F6PVQ7 F6PVQ7 LOC100175981 PTHR11716:SF106 PHOSPHOLIPASE A2 FAMILY MEMBER PHOSPHOLIPASE A2 A2-ACTITOXIN-UCS2A-LIKE cation binding#GO:0043169;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;phospholipase A2 activity#GO:0004623;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;lipid binding#GO:0008289;phospholipase activity#GO:0004620;ion binding#GO:0043167;phospholipid binding#GO:0005543 lipid metabolic process#GO:0006629;cellular metabolic process#GO:0044237;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;phospholipid metabolic process#GO:0006644;cellular lipid metabolic process#GO:0044255;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 phospholipase#PC00186 CIOIN|Ensembl=ENSCING00000015331.2|UniProtKB=F7APD9 F7APD9 PTHR11243:SF23 GROWTH FACTOR RECEPTOR-BOUND PROTEIN LD06925P scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000011649.2|UniProtKB=F6ZN29 F6ZN29 LOC100187176 PTHR46473:SF10 GH08155P LD45603P-RELATED CIOIN|Ensembl=ENSCING00000007964.3|UniProtKB=F6Z7W1 F6Z7W1 PTHR10972:SF102 OXYSTEROL-BINDING PROTEIN-RELATED OXYSTEROL-BINDING PROTEIN binding#GO:0005488;organic cyclic compound binding#GO:0097159;steroid binding#GO:0005496;sterol transporter activity#GO:0015248;sterol binding#GO:0032934;lipid binding#GO:0008289;lipid transporter activity#GO:0005319;transporter activity#GO:0005215 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;membrane#GO:0016020;intracellular anatomical structure#GO:0005622 transfer/carrier protein#PC00219 CIOIN|Ensembl=ENSCING00000022366.1|UniProtKB=H2XST3 H2XST3 PTHR11101:SF80 PHOSPHATE TRANSPORTER PHOSPHATE TRANSPORTER inorganic molecular entity transmembrane transporter activity#GO:0015318;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 localization#GO:0051179;inorganic anion transmembrane transport#GO:0098661;phosphate ion transport#GO:0006817;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;transport#GO:0006810;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;inorganic anion transport#GO:0015698 transporter#PC00227 CIOIN|Ensembl=ENSCING00000015485.2|UniProtKB=F6TVS6 F6TVS6 LOC778889 PTHR11085:SF10 NAD-DEPENDENT PROTEIN DEACYLASE SIRTUIN-5, MITOCHONDRIAL-RELATED NAD-DEPENDENT PROTEIN DEACYLASE SIRTUIN-5, MITOCHONDRIAL-RELATED nucleotide binding#GO:0000166;histone modifying activity#GO:0140993;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;deacetylase activity#GO:0019213;histone deacetylase activity#GO:0004407;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;anion binding#GO:0043168;catalytic activity, acting on a protein#GO:0140096 CIOIN|Ensembl=ENSCING00000023725.1|UniProtKB=H2XRC5 H2XRC5 PTHR10257:SF89 SERINE/THREONINE PROTEIN PHOSPHATASE 2A PP2A REGULATORY SUBUNIT B SERINE_THREONINE-PROTEIN PHOSPHATASE 2A 56 KDA REGULATORY SUBUNIT DELTA ISOFORM phosphatase regulator activity#GO:0019208;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;protein phosphatase regulator activity#GO:0019888 macromolecule modification#GO:0043412;nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;dephosphorylation#GO:0016311;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein dephosphorylation#GO:0006470;cellular metabolic process#GO:0044237;protein metabolic process#GO:0019538;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;protein serine/threonine phosphatase complex#GO:0008287;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein phosphatase#PC00195;protein modifying enzyme#PC00260 Wnt signaling pathway#P00057>PP2A#P01438;FGF signaling pathway#P00021>PP2A#P00629;EGF receptor signaling pathway#P00018>PP2A#P00547 CIOIN|Ensembl=ENSCING00000000720.3|UniProtKB=F6Q599 F6Q599 LOC100184589 PTHR23310:SF77 ACYL-COA-BINDING PROTEIN, ACBP LD25952P carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;amide binding#GO:0033218;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;lipid binding#GO:0008289;anion binding#GO:0043168;ion binding#GO:0043167 lipid metabolic process#GO:0006629;oxoacid metabolic process#GO:0043436;fatty acid metabolic process#GO:0006631;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular lipid metabolic process#GO:0044255;organic acid metabolic process#GO:0006082;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 transfer/carrier protein#PC00219 CIOIN|Ensembl=ENSCING00000014791.2|UniProtKB=F6VLE7 F6VLE7 PTHR19325:SF567 COMPLEMENT COMPONENT-RELATED SUSHI DOMAIN-CONTAINING SUSHI, VON WILLEBRAND FACTOR TYPE A, EGF AND PENTRAXIN DOMAIN-CONTAINING PROTEIN 1-LIKE complement component#PC00078 CIOIN|Ensembl=ENSCING00000024528.1|UniProtKB=H2XXZ7 H2XXZ7 LOC100186457 PTHR10836:SF76 GLYCERALDEHYDE 3-PHOSPHATE DEHYDROGENASE GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE-RELATED dehydrogenase#PC00092;oxidoreductase#PC00176 Glycolysis#P00024>Glyceraldehyde 3-phosphate dehydrogenase#P00676;Huntington disease#P00029>GAPDH#P00810 CIOIN|Ensembl=ENSCING00000024504.1|UniProtKB=H2Y3N1 H2Y3N1 PTHR46788:SF1 EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 5 EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 5 calmodulin-related#PC00061 CIOIN|Ensembl=ENSCING00000011422.2|UniProtKB=F7AWP7 F7AWP7 PTHR13132:SF29 ALPHA- 1,6 -FUCOSYLTRANSFERASE ALPHA-(1,6)-FUCOSYLTRANSFERASE transferase activity#GO:0016740;fucosyltransferase activity#GO:0008417;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein glycosylation#GO:0006486;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein N-linked glycosylation#GO:0006487;protein metabolic process#GO:0019538;glycosylation#GO:0070085;glycoprotein metabolic process#GO:0009100;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 glycosyltransferase#PC00111 Notch signaling pathway#P00045>Neurotic#P01115 CIOIN|Ensembl=ENSCING00000012407.2|UniProtKB=F6TL82 F6TL82 LOC100184193 PTHR11360:SF284 MONOCARBOXYLATE TRANSPORTER EG:103B4.3 PROTEIN-RELATED transporter#PC00227 CIOIN|Ensembl=ENSCING00000022474.1|UniProtKB=H2XMA6 H2XMA6 PTHR13869:SF24 MYELIN P0 RELATED BASEMENT MEMBRANE-SPECIFIC HEPARAN SULFATE PROTEOGLYCAN CORE PROTEIN-LIKE myelin protein#PC00161;structural protein#PC00211 CIOIN|Ensembl=ENSCING00000020229.1|UniProtKB=H2XZA1 H2XZA1 PTHR11929:SF145 ALPHA- 1,3 -FUCOSYLTRANSFERASE ALPHA-(1,3)-FUCOSYLTRANSFERASE FUT-1 transferase activity#GO:0016740;fucosyltransferase activity#GO:0008417;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 glycosylation#GO:0070085;metabolic process#GO:0008152 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000018529.1|UniProtKB=H2Y340 H2Y340 PTHR19836:SF19 30S RIBOSOMAL PROTEIN S14 SMALL RIBOSOMAL SUBUNIT PROTEIN US14M structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;small ribosomal subunit#GO:0015935;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000004353.3|UniProtKB=A0A1W3JIQ6 A0A1W3JIQ6 LOC100180409 PTHR10848:SF0 MEIOTIC RECOMBINATION PROTEIN SPO11 MEIOTIC RECOMBINATION PROTEIN SPO11 endodeoxyribonuclease#PC00093 CIOIN|Ensembl=ENSCING00000007292.4|UniProtKB=F6XY03 F6XY03 PTHR11528:SF97 HEAT SHOCK PROTEIN 90 FAMILY MEMBER ENDOPLASMIN protein binding#GO:0005515;unfolded protein binding#GO:0051082;binding#GO:0005488 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein folding#GO:0006457;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 Hsp90 family chaperone#PC00028 CIOIN|Ensembl=ENSCING00000002700.3|UniProtKB=F6UE33 F6UE33 PTHR10663:SF375 GUANYL-NUCLEOTIDE EXCHANGE FACTOR LD29171P guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 CIOIN|Ensembl=ENSCING00000004044.3|UniProtKB=Q4H2R0 Q4H2R0 Ci-STAT-b PTHR11801:SF43 SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION SIGNAL TRANSDUCER AND TRANSCRIPTION ACTIVATOR sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;Rel homology transcription factor#PC00252;immunoglobulin fold transcription factor#PC00251 PDGF signaling pathway#P00047>STAT#P01173;EGF receptor signaling pathway#P00018>STAT#P00561 CIOIN|Ensembl=ENSCING00000000418.3|UniProtKB=F7BL51 F7BL51 PTHR43172:SF1 ADENYLOSUCCINATE LYASE ADENYLOSUCCINATE LYASE lyase activity#GO:0016829;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;purine ribonucleoside monophosphate metabolic process#GO:0009167;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;nucleotide biosynthetic process#GO:0009165;nucleoside monophosphate metabolic process#GO:0009123;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;purine nucleoside monophosphate metabolic process#GO:0009126;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;ribonucleoside monophosphate metabolic process#GO:0009161;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 lyase#PC00144 De novo purine biosynthesis#P02738>Adenosuccinate lyase#P02901;De novo purine biosynthesis#P02738>5-Phosphoribosyl-4-(N-succinocarboxamide)-5-aminoimidazole lyase#P02892 CIOIN|Ensembl=ENSCING00000002100.3|UniProtKB=F6ZRJ2 F6ZRJ2 PTHR23043:SF17 HYPOXIA-INDUCIBLE FACTOR 1 ALPHA PROTEIN SIMILAR basic helix-loop-helix transcription factor#PC00055 CIOIN|Ensembl=ENSCING00000019895.1|UniProtKB=H2XKE5 H2XKE5 PTHR16134:SF119 F-BOX/TPR REPEAT PROTEIN POF3 AT02038P-RELATED ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000020879.1|UniProtKB=H2XSF5 H2XSF5 PTHR10342:SF274 ARYLSULFATASE ARYLSULFATASE B CIOIN|Ensembl=ENSCING00000012145.2|UniProtKB=F6TN36 F6TN36 PTHR23254:SF17 EIF4G DOMAIN PROTEIN MIF4G DOMAIN-CONTAINING PROTEIN nucleic acid binding#GO:0003676;translation regulator activity#GO:0045182;translation regulator activity, nucleic acid binding#GO:0090079;binding#GO:0005488;organic cyclic compound binding#GO:0097159 regulation of protein metabolic process#GO:0051246;regulation of amide metabolic process#GO:0034248;regulation of nitrogen compound metabolic process#GO:0051171;regulation of translational initiation#GO:0006446;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biosynthetic process#GO:0009889;post-transcriptional regulation of gene expression#GO:0010608;biological regulation#GO:0065007;regulation of translation#GO:0006417;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000006677.3|UniProtKB=H2XX78 H2XX78 PTHR14991:SF0 RING FINGER PROTEIN 32 RING FINGER PROTEIN 32 CIOIN|Ensembl=ENSCING00000007847.3|UniProtKB=F6VJG0 F6VJG0 LOC100185145 PTHR24023:SF1072 COLLAGEN ALPHA CO7A1 PROTEIN structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;external encapsulating structure organization#GO:0045229;extracellular matrix organization#GO:0030198 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;extracellular region#GO:0005576 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 CIOIN|Ensembl=ENSCING00000013004.2|UniProtKB=F6V6M0 F6V6M0 PTHR45990:SF1 DNA REPAIR PROTEIN REV1 DNA REPAIR PROTEIN REV1 DNA-directed DNA polymerase activity#GO:0003887;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on DNA#GO:0140097;DNA polymerase activity#GO:0034061 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;postreplication repair#GO:0006301;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;translesion synthesis#GO:0019985;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;nucleobase-containing compound biosynthetic process#GO:0034654;DNA biosynthetic process#GO:0071897;DNA synthesis involved in DNA repair#GO:0000731;aromatic compound biosynthetic process#GO:0019438;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA metabolism protein#PC00009 CIOIN|Ensembl=ENSCING00000006937.3|UniProtKB=F6V062 F6V062 PTHR46218:SF4 LASP LIM AND SH3 DOMAIN PROTEIN LASP CIOIN|Ensembl=ENSCING00000006744.3|UniProtKB=A0A1W5BQ23 A0A1W5BQ23 LOC100181766 PTHR45834:SF3 RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 9-RELATED RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 3, ISOFORM L nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;guanyl-nucleotide exchange factor activity#GO:0005085 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 CIOIN|Ensembl=ENSCING00000022197.1|UniProtKB=H2XUF0 H2XUF0 PTHR28163:SF1 PROTEIN PET117 HOMOLOG, MITOCHONDRIAL PROTEIN PET117 HOMOLOG, MITOCHONDRIAL cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;respiratory chain complex IV assembly#GO:0008535;mitochondrial respiratory chain complex assembly#GO:0033108;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;cytochrome complex assembly#GO:0017004;protein-containing complex assembly#GO:0065003;mitochondrial cytochrome c oxidase assembly#GO:0033617;mitochondrion organization#GO:0007005;cellular component organization#GO:0016043;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000005372.3|UniProtKB=F7BEM7 F7BEM7 PTHR10404:SF81 N-ACETYLATED-ALPHA-LINKED ACIDIC DIPEPTIDASE N-ACETYLATED ALPHA-LINKED ACIDIC DIPEPTIDASE 2 hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;carboxypeptidase activity#GO:0004180 metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000005106.2|UniProtKB=F6WKB1 F6WKB1 PTHR16146:SF46 INTELECTIN INTELECTIN-1A-RELATED CIOIN|Ensembl=ENSCING00000012044.2|UniProtKB=F7AMY5 F7AMY5 LOC100186983 PTHR28554:SF1 39S RIBOSOMAL PROTEIN L45, MITOCHONDRIAL LARGE RIBOSOMAL SUBUNIT PROTEIN ML45 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000003002.3|UniProtKB=Q68A28 Q68A28 Ci-PER-like PTHR10681:SF163 THIOREDOXIN PEROXIDASE AT16346P-RELATED oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;antioxidant activity#GO:0016209;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;response to stress#GO:0006950;catabolic process#GO:0009056;cellular metabolic process#GO:0044237;homeostatic process#GO:0042592;response to oxidative stress#GO:0006979;cellular process#GO:0009987;cellular response to stress#GO:0033554;cellular homeostasis#GO:0019725;cellular catabolic process#GO:0044248;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 peroxidase#PC00180;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000021662.1|UniProtKB=H2XMK8 H2XMK8 PTHR46885:SF1 PROTEIN ANKUB1 PROTEIN ANKUB1 CIOIN|Ensembl=ENSCING00000006008.3|UniProtKB=F6T2X1 F6T2X1 PTHR11024:SF3 NUCLEAR PORE COMPLEX PROTEIN SEC13 / SEH1 FAMILY MEMBER NUCLEOPORIN SEH1 positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;response to extracellular stimulus#GO:0009991;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;cellular response to starvation#GO:0009267;positive regulation of TOR signaling#GO:0032008;regulation of signal transduction#GO:0009966;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;cellular response to extracellular stimulus#GO:0031668;regulation of cell communication#GO:0010646;positive regulation of TORC1 signaling#GO:1904263;cellular response to stimulus#GO:0051716;regulation of TORC1 signaling#GO:1903432;cell communication#GO:0007154;response to nutrient levels#GO:0031667;cellular process#GO:0009987;regulation of TOR signaling#GO:0032006;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;response to stress#GO:0006950;cellular response to nutrient levels#GO:0031669;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;response to starvation#GO:0042594;biological regulation#GO:0065007;cellular response to external stimulus#GO:0071496;cellular response to amino acid starvation#GO:0034198;cellular response to stress#GO:0033554 envelope#GO:0031975;nuclear pore#GO:0005643;protein-containing complex#GO:0032991;Seh1-associated complex#GO:0035859;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear envelope#GO:0005635;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;organelle envelope#GO:0031967;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transporter#PC00227 CIOIN|Ensembl=ENSCING00000017647.2|UniProtKB=F6TBZ1 F6TBZ1 PTHR24388:SF104 ZINC FINGER PROTEIN AT-RICH BINDING PROTEIN-RELATED sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 CIOIN|Ensembl=ENSCING00000012690.2|UniProtKB=F6TFV0 F6TFV0 LOC100186893 PTHR10344:SF4 THYMIDYLATE KINASE UMP-CMP KINASE 2, MITOCHONDRIAL transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;phosphotransferase activity, phosphate group as acceptor#GO:0016776 cellular aromatic compound metabolic process#GO:0006725;nucleoside triphosphate metabolic process#GO:0009141;pyrimidine nucleotide metabolic process#GO:0006220;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;pyrimidine-containing compound metabolic process#GO:0072527;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;nucleoside diphosphate metabolic process#GO:0009132;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;nucleoside triphosphate biosynthetic process#GO:0009142;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 nucleotide kinase#PC00172 De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>dTMP kinase#P02916 CIOIN|Ensembl=ENSCING00000015308.2|UniProtKB=H2XU68 H2XU68 PTHR11346:SF176 GALECTIN 32 KDA BETA-GALACTOSIDE-BINDING LECTIN LEC-3 carbohydrate binding#GO:0030246;binding#GO:0005488 extracellular matrix protein#PC00102 CIOIN|Ensembl=ENSCING00000006475.3|UniProtKB=F6Q4V5 F6Q4V5 PTHR23050:SF354 CALCIUM BINDING PROTEIN EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 11 cation binding#GO:0043169;small molecule binding#GO:0036094;molecular function regulator activity#GO:0098772;binding#GO:0005488;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;enzyme regulator activity#GO:0030234 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 calmodulin-related#PC00061 CIOIN|Ensembl=ENSCING00000012886.2|UniProtKB=F6QWK4 F6QWK4 LOC100177655 PTHR42790:SF23 AMINOTRANSFERASE AROMATIC AMINO ACID AMINOTRANSFERASE DDB_G0272014 transaminase activity#GO:0008483;transferase activity#GO:0016740;catalytic activity#GO:0003824 oxoacid metabolic process#GO:0043436;nitrogen compound metabolic process#GO:0006807;alpha-amino acid metabolic process#GO:1901605;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;carboxylic acid metabolic process#GO:0019752;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 transaminase#PC00216 CIOIN|Ensembl=ENSCING00000005940.3|UniProtKB=F6YYJ3 F6YYJ3 PTHR19325:SF567 COMPLEMENT COMPONENT-RELATED SUSHI DOMAIN-CONTAINING SUSHI, VON WILLEBRAND FACTOR TYPE A, EGF AND PENTRAXIN DOMAIN-CONTAINING PROTEIN 1-LIKE complement component#PC00078 CIOIN|Ensembl=ENSCING00000024876.1|UniProtKB=H2XY58 H2XY58 PTHR45774:SF3 BTB/POZ DOMAIN-CONTAINING BTB (POZ) DOMAIN-CONTAINING 2B-RELATED ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000005883.3|UniProtKB=F6T4T6 F6T4T6 LOC100183475 PTHR21532:SF0 PHOSPHODIESTERASE HL CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 36 axoneme#GO:0005930;ciliary base#GO:0097546;cytoplasmic region#GO:0099568;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;plasma membrane bounded cell projection cytoplasm#GO:0032838;ciliary plasm#GO:0097014;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cytoskeleton#GO:0005856;cilium#GO:0005929 phosphodiesterase#PC00185;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000006504.3|UniProtKB=F7AHA3 F7AHA3 PTHR10728:SF40 CYTOSOLIC PHOSPHOLIPASE A2 PATATIN FAMILY PROTEIN hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;phospholipase A2 activity#GO:0004623;phospholipase activity#GO:0004620;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;cellular metabolic process#GO:0044237;glycerophospholipid metabolic process#GO:0006650;glycerolipid catabolic process#GO:0046503;lipid catabolic process#GO:0016042;glycerophospholipid catabolic process#GO:0046475;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate catabolic process#GO:0046434;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;phospholipid catabolic process#GO:0009395;catabolic process#GO:0009056;organophosphate metabolic process#GO:0019637;organic substance catabolic process#GO:1901575;cellular lipid metabolic process#GO:0044255;cellular lipid catabolic process#GO:0044242;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 phospholipase#PC00186 CIOIN|Ensembl=ENSCING00000005386.3|UniProtKB=F7AVL3 F7AVL3 PTHR10174:SF225 ALPHA-TOCOPHEROL TRANSFER PROTEIN-RELATED ALPHA-TOCOPHEROL TRANSFER PROTEIN phosphatidylinositol bisphosphate binding#GO:1902936;lipid binding#GO:0008289;phosphatidylinositol binding#GO:0035091;phospholipid binding#GO:0005543;phosphatidylinositol phosphate binding#GO:1901981;binding#GO:0005488 cellular anatomical entity#GO:0110165;membrane#GO:0016020 transfer/carrier protein#PC00219 CIOIN|Ensembl=ENSCING00000004662.3|UniProtKB=F6RHG2 F6RHG2 LOC100176748 PTHR11124:SF12 VACUOLAR SORTING PROTEIN VPS29 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 29 vesicle coat protein#PC00235 CIOIN|Ensembl=ENSCING00000016619.2|UniProtKB=F6UPT3 F6UPT3 PTHR24304:SF4 CYTOCHROME P450 FAMILY 7 CYTOCHROME P450 steroid hydroxylase activity#GO:0008395;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497 organic acid biosynthetic process#GO:0016053;organic hydroxy compound metabolic process#GO:1901615;oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;monocarboxylic acid biosynthetic process#GO:0072330;cellular metabolic process#GO:0044237;homeostatic process#GO:0042592;cellular biosynthetic process#GO:0044249;organic hydroxy compound biosynthetic process#GO:1901617;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;chemical homeostasis#GO:0048878;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;organic acid metabolic process#GO:0006082;cholesterol homeostasis#GO:0042632;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;steroid metabolic process#GO:0008202;organic cyclic compound metabolic process#GO:1901360;lipid homeostasis#GO:0055088;small molecule biosynthetic process#GO:0044283;carboxylic acid metabolic process#GO:0019752;steroid biosynthetic process#GO:0006694;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 oxygenase#PC00177;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000002406.2|UniProtKB=F6QI37 F6QI37 LOC100179994 PTHR43127:SF2 DEVELOPMENTALLY-REGULATED GTP-BINDING PROTEIN 2 DEVELOPMENTALLY-REGULATED GTP-BINDING PROTEIN 2 carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cytoplasmic translation#GO:0002181;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000007843.3|UniProtKB=F6WSG2 F6WSG2 PTHR11785:SF512 AMINO ACID TRANSPORTER SOBREMESA, ISOFORM B L-amino acid transmembrane transporter activity#GO:0015179;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;amino acid transmembrane transporter activity#GO:0015171;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215;organic acid transmembrane transporter activity#GO:0005342 localization#GO:0051179;organic substance transport#GO:0071702;amino acid transmembrane transport#GO:0003333;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;amino acid transport#GO:0006865;organic anion transport#GO:0015711;organic acid transport#GO:0015849;transport#GO:0006810;nitrogen compound transport#GO:0071705;organic acid transmembrane transport#GO:1903825;carboxylic acid transport#GO:0046942;cellular process#GO:0009987;carboxylic acid transmembrane transport#GO:1905039 transporter#PC00227 CIOIN|Ensembl=ENSCING00000018936.1|UniProtKB=H2XYF5 H2XYF5 LOC100178444 PTHR10969:SF37 MICROTUBULE-ASSOCIATED PROTEINS 1A/1B LIGHT CHAIN 3-RELATED PROTEIN LGG-2 cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;binding#GO:0005488;ubiquitin-like protein ligase binding#GO:0044389;enzyme binding#GO:0019899;protein binding#GO:0005515;microtubule binding#GO:0008017;lipid binding#GO:0008289;ubiquitin protein ligase binding#GO:0031625;phospholipid binding#GO:0005543 cellular component biogenesis#GO:0044085;macroautophagy#GO:0016236;autophagy of mitochondrion#GO:0000422;response to extracellular stimulus#GO:0009991;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;cellular component disassembly#GO:0022411;cellular response to starvation#GO:0009267;catabolic process#GO:0009056;mitochondrion organization#GO:0007005;autophagosome maturation#GO:0097352;cellular response to extracellular stimulus#GO:0031668;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;cellular component assembly#GO:0022607;cellular response to stimulus#GO:0051716;protein-containing complex disassembly#GO:0032984;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cell communication#GO:0007154;response to nutrient levels#GO:0031667;cellular process#GO:0009987;organelle disassembly#GO:1903008;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;response to stress#GO:0006950;cellular response to nutrient levels#GO:0031669;protein-containing complex organization#GO:0043933;organelle organization#GO:0006996;response to starvation#GO:0042594;cellular response to external stimulus#GO:0071496;autophagosome assembly#GO:0000045;cellular response to stress#GO:0033554;autophagy#GO:0006914 bounding membrane of organelle#GO:0098588;cytoplasm#GO:0005737;autophagosome membrane#GO:0000421;intracellular membrane-bounded organelle#GO:0043231;vacuolar membrane#GO:0005774;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;autophagosome#GO:0005776;intracellular anatomical structure#GO:0005622 non-motor microtubule binding protein#PC00166 CIOIN|Ensembl=ENSCING00000001119.3|UniProtKB=F6ZDE8 F6ZDE8 PTHR11786:SF0 N-HYDROXYARYLAMINE O-ACETYLTRANSFERASE ARYLAMINE N-ACETYLTRANSFERASE 4-RELATED acetyltransferase#PC00038 CIOIN|Ensembl=ENSCING00000008648.3|UniProtKB=F6ZYJ2 F6ZYJ2 LOC100180764 PTHR10281:SF1 MEMBRANE-ASSOCIATED PROGESTERONE RECEPTOR COMPONENT-RELATED VACUOLE MEMBRANE PROTEIN 1 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transmembrane signal receptor#PC00197 CIOIN|Ensembl=ENSCING00000024414.1|UniProtKB=H2XME3 H2XME3 LOC100180975 PTHR11753:SF2 ADAPTOR COMPLEXES SMALL SUBUNIT FAMILY ADAPTOR PROTEIN COMPLEX AP-3 SMALL CHAIN SIGMA3 localization#GO:0051179;vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234;cellular process#GO:0009987;transport#GO:0006810 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 vesicle coat protein#PC00235 CIOIN|Ensembl=ENSCING00000009361.3|UniProtKB=A0A1W3JJ67 A0A1W3JJ67 LOC100180800 PTHR44140:SF2 LD25575P LD25575P protein binding#GO:0005515;protein-folding chaperone binding#GO:0051087;binding#GO:0005488 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein folding#GO:0006457;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000006957.3|UniProtKB=F6SYL0 F6SYL0 LOC100184511 PTHR11588:SF504 TUBULIN TUBULIN BETA-1 CHAIN-RELATED carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;structural molecule activity#GO:0005198;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167;structural constituent of cytoskeleton#GO:0005200 cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;microtubule-based process#GO:0007017;organelle organization#GO:0006996;microtubule cytoskeleton organization#GO:0000226;cytoskeleton organization#GO:0007010;cell cycle#GO:0007049;cellular component organization#GO:0016043;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622 tubulin#PC00228;microtubule or microtubule-binding cytoskeletal protein#PC00157 Huntington disease#P00029>Microtubule#P00780;Huntington disease#P00029>beta-Tubulin#P00790;Cytoskeletal regulation by Rho GTPase#P00016>tubulin#P00526 CIOIN|Ensembl=ENSCING00000003513.3|UniProtKB=F7BHL3 F7BHL3 LOC100179089 PTHR24264:SF65 TRYPSIN-RELATED SRCR DOMAIN-CONTAINING PROTEIN hydrolase activity#GO:0016787;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 serine protease#PC00203;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000005024.3|UniProtKB=F6TX35 F6TX35 LOC100184960 PTHR15271:SF4 CHROMATIN ASSEMBLY FACTOR 1 SUBUNIT B CHROMATIN ASSEMBLY FACTOR 1 SUBUNIT B cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;protein-DNA complex organization#GO:0071824;nucleosome organization#GO:0034728;nucleosome assembly#GO:0006334;protein-containing complex organization#GO:0043933;protein-containing complex assembly#GO:0065003;chromatin organization#GO:0006325;cellular component organization#GO:0016043;cellular process#GO:0009987;chromatin remodeling#GO:0006338;protein-DNA complex assembly#GO:0065004 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 CIOIN|Ensembl=ENSCING00000001380.3|UniProtKB=F6S8X6 F6S8X6 PTHR10064:SF0 60S RIBOSOMAL PROTEIN L22 FI24544P1-RELATED structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;structural molecule activity#GO:0005198;binding#GO:0005488;organic cyclic compound binding#GO:0097159 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cytoplasmic translation#GO:0002181;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;translation#GO:0006412;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 ribosomal protein#PC00202;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000023705.1|UniProtKB=H2XXM2 H2XXM2 PTHR44523:SF1 TETRATRICOPEPTIDE REPEAT PROTEIN 13 TETRATRICOPEPTIDE REPEAT PROTEIN 13 CIOIN|Ensembl=ENSCING00000014906.2|UniProtKB=F6Y820 F6Y820 LOC100182253 PTHR18834:SF2 STEROID RECEPTOR RNA ACTIVATOR 1 STEROID RECEPTOR RNA ACTIVATOR 1 transcription coactivator activity#GO:0003713;transcription coregulator activity#GO:0003712;molecular adaptor activity#GO:0060090;transcription regulator activity#GO:0140110;nuclear receptor coactivator activity#GO:0030374;protein-macromolecule adaptor activity#GO:0030674 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000024948.1|UniProtKB=H2XZZ8 H2XZZ8 LOC100175756 PTHR10725:SF78 THAP DOMAIN-CONTAINING PROTEIN 9 DNA TRANSPOSASE THAP9 CIOIN|Ensembl=ENSCING00000001818.3|UniProtKB=F6WIW4 F6WIW4 dp-1 PTHR12548:SF9 TRANSCRIPTION FACTOR DP TRANSCRIPTION FACTOR DP sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 CIOIN|Ensembl=ENSCING00000023475.1|UniProtKB=H2XX80 H2XX80 PTHR23349:SF72 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, TWIST HLH54F sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 basic helix-loop-helix transcription factor#PC00055 CIOIN|Ensembl=ENSCING00000012747.2|UniProtKB=F7A8W7 F7A8W7 PTHR11929:SF145 ALPHA- 1,3 -FUCOSYLTRANSFERASE ALPHA-(1,3)-FUCOSYLTRANSFERASE FUT-1 transferase activity#GO:0016740;fucosyltransferase activity#GO:0008417;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 glycosylation#GO:0070085;metabolic process#GO:0008152 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000000238.3|UniProtKB=F6T310 F6T310 PTHR21208:SF0 ADP-DEPENDENT GLUCOKINASE ADP-DEPENDENT GLUCOKINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301 monosaccharide metabolic process#GO:0005996;hexose metabolic process#GO:0019318;carbohydrate metabolic process#GO:0005975;glucose metabolic process#GO:0006006;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transferase#PC00220;kinase#PC00137;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000002874.3|UniProtKB=F6SDI7 F6SDI7 PTHR11909:SF428 CASEIN KINASE-RELATED CASEIN KINASE I ISOFORM EPSILON transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of protein metabolic process#GO:0051246;regulation of catabolic process#GO:0009894;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;regulation of proteolysis involved in protein catabolic process#GO:1903050;positive regulation of proteolysis#GO:0045862;regulation of biological process#GO:0050789;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of proteolysis involved in protein catabolic process#GO:1903052;macromolecule metabolic process#GO:0043170;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cellular metabolic process#GO:0044237;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;positive regulation of canonical Wnt signaling pathway#GO:0090263;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;positive regulation of catabolic process#GO:0009896;positive regulation of protein catabolic process#GO:0045732;import into cell#GO:0098657;regulation of metabolic process#GO:0019222;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;macromolecule modification#GO:0043412;regulation of signaling#GO:0023051;transport#GO:0006810;positive regulation of proteasomal protein catabolic process#GO:1901800;protein modification process#GO:0036211;regulation of protein catabolic process#GO:0042176;peptidyl-amino acid modification#GO:0018193;positive regulation of Wnt signaling pathway#GO:0030177;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;positive regulation of response to stimulus#GO:0048584;positive regulation of metabolic process#GO:0009893;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;signaling#GO:0023052;positive regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032436;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;metabolic process#GO:0008152;regulation of cell communication#GO:0010646;regulation of proteolysis#GO:0030162;cellular response to stimulus#GO:0051716;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular process#GO:0009987;regulation of canonical Wnt signaling pathway#GO:0060828;regulation of proteasomal protein catabolic process#GO:0061136;regulation of primary metabolic process#GO:0080090;localization#GO:0051179;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of macromolecule metabolic process#GO:0060255;regulation of Wnt signaling pathway#GO:0030111;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 Wnt signaling pathway#P00057>Casein Kinase 1#P01460;CCKR signaling map#P06959>CK1delta/epsilon#P07089;Hedgehog signaling pathway#P00025>Casein kinase I#P00681;Circadian clock system#P00015>Casein kinase I#P00502;Parkinson disease#P00049>Casein kinase I#P01242 CIOIN|Ensembl=ENSCING00000013197.2|UniProtKB=F6Z4P5 F6Z4P5 PTHR22802:SF379 C-TYPE LECTIN SUPERFAMILY MEMBER CHONDROITIN SULFATE PROTEOGLYCAN 2 ISOFORM X1 membrane traffic protein#PC00150 CIOIN|Ensembl=ENSCING00000007470.3|UniProtKB=F6YIF4 F6YIF4 PTHR24419:SF34 INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASE PROTEIN TUBE-RELATED histone modifying activity#GO:0140993;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;mitotic cell cycle#GO:0000278;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell cycle#GO:0007049;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;signaling#GO:0023052 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 Toll pathway-drosophila#P06217>PLL#P06338 CIOIN|Ensembl=ENSCING00000016593.2|UniProtKB=F6W0Q4 F6W0Q4 PTHR12608:SF1 TRANSMEMBRANE PROTEIN HTP-1 RELATED TRANSMEMBRANE PROTEIN 165 inorganic molecular entity transmembrane transporter activity#GO:0015318;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;monoatomic ion transmembrane transporter activity#GO:0015075;inorganic cation transmembrane transporter activity#GO:0022890;metal ion transmembrane transporter activity#GO:0046873 CIOIN|Ensembl=ENSCING00000006832.3|UniProtKB=F7AZV4 F7AZV4 PTHR11616:SF182 SODIUM/CHLORIDE DEPENDENT TRANSPORTER TRANSPORTER metal ion transport#GO:0030001;transmembrane transport#GO:0055085;amino acid transport#GO:0006865;organic anion transport#GO:0015711;organic acid transport#GO:0015849;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;localization#GO:0051179;organic substance transport#GO:0071702;sodium ion transport#GO:0006814;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;sodium ion transmembrane transport#GO:0035725 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 primary active transporter#PC00068;transporter#PC00227 Adrenaline and noradrenaline biosynthesis#P00001>amine translocator#P00068 CIOIN|Ensembl=ENSCING00000020525.1|UniProtKB=H2XWI8 H2XWI8 PTHR16056:SF16 REGULATOR OF MICROTUBULE DYNAMICS PROTEIN REGULATOR OF MICROTUBULE DYNAMICS PROTEIN 1 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 supramolecular complex#GO:0099080;spindle pole#GO:0000922;spindle microtubule#GO:0005876;cellular anatomical entity#GO:0110165;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;mitotic spindle#GO:0072686;microtubule cytoskeleton#GO:0015630;cytoskeleton#GO:0005856;microtubule#GO:0005874;spindle#GO:0005819 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 CIOIN|Ensembl=ENSCING00000006015.3|UniProtKB=F6ZGG6 F6ZGG6 LOC100178141 PTHR13952:SF5 U1 SMALL NUCLEAR RIBONUCLEOPROTEIN 70 KD U1 SMALL NUCLEAR RIBONUCLEOPROTEIN 70 KDA nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;snRNA binding#GO:0017069;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;mRNA splicing, via spliceosome#GO:0000398;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;U1 snRNP#GO:0005685;U2-type spliceosomal complex#GO:0005684;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;spliceosomal snRNP complex#GO:0097525;small nuclear ribonucleoprotein complex#GO:0030532;protein-containing complex#GO:0032991;U2-type prespliceosome#GO:0071004;precatalytic spliceosome#GO:0071011;membrane-bounded organelle#GO:0043227;Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513 RNA splicing factor#PC00148;RNA processing factor#PC00147;RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000006951.3|UniProtKB=F6VN10 F6VN10 LOC100182227 PTHR23359:SF70 NUCLEOTIDE KINASE ADENYLATE KINASE 1, ISOFORM B transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, phosphate group as acceptor#GO:0016776;catalytic activity#GO:0003824;kinase activity#GO:0016301 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 nucleotide kinase#PC00172;kinase#PC00137 De novo purine biosynthesis#P02738>Adenylate kinase#P02896 CIOIN|Ensembl=ENSCING00000009362.3|UniProtKB=F6WYH0 F6WYH0 LOC100182056 PTHR10082:SF60 INTEGRIN BETA SUBUNIT INTEGRIN BETA-PS cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;integrin binding#GO:0005178;binding#GO:0005488;signaling receptor binding#GO:0005102 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cell adhesion mediated by integrin#GO:0033627;cell-cell adhesion#GO:0098609;cell motility#GO:0048870;cell adhesion#GO:0007155;cell communication#GO:0007154;cell-substrate adhesion#GO:0031589;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cell-matrix adhesion#GO:0007160;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;integrin-mediated signaling pathway#GO:0007229;cell migration#GO:0016477;signaling#GO:0023052 receptor complex#GO:0043235;membrane protein complex#GO:0098796;cell surface#GO:0009986;protein-containing complex#GO:0032991;plasma membrane signaling receptor complex#GO:0098802;anchoring junction#GO:0070161;plasma membrane protein complex#GO:0098797;focal adhesion#GO:0005925;cell junction#GO:0030054;cell-substrate junction#GO:0030055;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cell adhesion molecule#PC00069;integrin#PC00126 Integrin signalling pathway#P00034>Integrin beta#P00931 CIOIN|Ensembl=ENSCING00000019348.1|UniProtKB=H2XJM2 H2XJM2 LOC100177436 PTHR15405:SF0 PROLINE-RICH NUCLEAR RECEPTOR COACTIVATOR AAQUETZALLI, ISOFORM A membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000002342.3|UniProtKB=F6PN13 F6PN13 LOC101242392 PTHR11960:SF18 EUKARYOTIC TRANSLATION INITIATION FACTOR 4E RELATED EUKARYOTIC TRANSLATION INITIATION FACTOR 4E HOMOLOGOUS PROTEIN, ISOFORM B nucleic acid binding#GO:0003676;RNA binding#GO:0003723;translation regulator activity#GO:0045182;binding#GO:0005488;organic cyclic compound binding#GO:0097159;translation initiation factor activity#GO:0003743;RNA cap binding#GO:0000339;translation regulator activity, nucleic acid binding#GO:0090079;translation factor activity, RNA binding#GO:0008135 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;translational initiation#GO:0006413;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;intracellular protein-containing complex#GO:0140535;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622 translation initiation factor#PC00224;translation factor#PC00223;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000014480.2|UniProtKB=F6XM44 F6XM44 LOC100176762 PTHR10502:SF233 ANNEXIN ANNEXIN B9 lipid binding#GO:0008289;phospholipid binding#GO:0005543;binding#GO:0005488;phosphatidylserine binding#GO:0001786 localization#GO:0051179;endosomal transport#GO:0016197;cellular localization#GO:0051641;establishment of localization#GO:0051234;transport#GO:0006810;endosome transport via multivesicular body sorting pathway#GO:0032509;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;cellular process#GO:0009987;multivesicular body sorting pathway#GO:0071985 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;vesicle membrane#GO:0012506;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 calcium-binding protein#PC00060 CIOIN|Ensembl=ENSCING00000023247.1|UniProtKB=H2XP13 H2XP13 PTHR10288:SF339 KH DOMAIN CONTAINING RNA BINDING PROTEIN RNA-BINDING PROTEIN PASILLA nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of biosynthetic process#GO:0009889;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000009268.3|UniProtKB=F6S1J5 F6S1J5 LOC100184237 PTHR11157:SF69 FATTY ACID ACYL TRANSFERASE-RELATED ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN 7 acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824 organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;monocarboxylic acid biosynthetic process#GO:0072330;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;organic acid metabolic process#GO:0006082;membrane lipid biosynthetic process#GO:0046467;sphingolipid metabolic process#GO:0006665;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;fatty acid metabolic process#GO:0006631;membrane lipid metabolic process#GO:0006643;nitrogen compound metabolic process#GO:0006807;small molecule biosynthetic process#GO:0044283;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;sphingolipid biosynthetic process#GO:0030148;fatty acid biosynthetic process#GO:0006633;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 acyltransferase#PC00042 CIOIN|Ensembl=ENSCING00000005388.3|UniProtKB=F7ABY6 F7ABY6 LOC100185860 PTHR14952:SF9 ROPPORIN-1-LIKE PROTEIN EF-HAND DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000024472.1|UniProtKB=H2XJJ6 H2XJJ6 LOC100175466 PTHR13509:SF3 SEC61 SUBUNIT BETA PROTEIN TRANSPORT PROTEIN SEC61 SUBUNIT BETA nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 cotranslational protein targeting to membrane#GO:0006613;cellular localization#GO:0051641;intracellular protein transmembrane transport#GO:0065002;macromolecule localization#GO:0033036;post-translational protein targeting to membrane, translocation#GO:0031204;transport#GO:0006810;protein transmembrane transport#GO:0071806;nitrogen compound transport#GO:0071705;establishment of protein localization#GO:0045184;SRP-dependent cotranslational protein targeting to membrane#GO:0006614;organic substance transport#GO:0071702;establishment of protein localization to membrane#GO:0090150;post-translational protein targeting to endoplasmic reticulum membrane#GO:0006620;establishment of localization#GO:0051234;protein localization to organelle#GO:0033365;establishment of protein localization to endoplasmic reticulum#GO:0072599;localization within membrane#GO:0051668;protein localization to endoplasmic reticulum#GO:0070972;transmembrane transport#GO:0055085;protein localization to membrane#GO:0072657;protein targeting#GO:0006605;establishment of protein localization to organelle#GO:0072594;protein targeting to ER#GO:0045047;cellular process#GO:0009987;protein localization#GO:0008104;localization#GO:0051179;protein targeting to membrane#GO:0006612;cellular macromolecule localization#GO:0070727;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 cellular anatomical entity#GO:0110165;membrane#GO:0016020 membrane traffic protein#PC00150 CIOIN|Ensembl=ENSCING00000015352.2|UniProtKB=F6TT57 F6TT57 PTHR24139:SF34 CALCIUM-INDEPENDENT PHOSPHOLIPASE A2 85_88 KDA CALCIUM-INDEPENDENT PHOSPHOLIPASE A2 carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;phospholipase A2 activity#GO:0004623;fatty acyl-CoA hydrolase activity#GO:0047617;catalytic activity#GO:0003824;thiolester hydrolase activity#GO:0016790;hydrolase activity#GO:0016787;phospholipase activity#GO:0004620 positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of amide metabolic process#GO:0034248;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of cellular component biogenesis#GO:0044087;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of lipid metabolic process#GO:0019216;regulation of lipid biosynthetic process#GO:0046890;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 phospholipase#PC00186 Gonadotropin-releasing hormone receptor pathway#P06664>PLA2#P06738 CIOIN|Ensembl=ENSCING00000020993.1|UniProtKB=H2XXD4 H2XXD4 PTHR35711:SF1 EXPRESSED PROTEIN ECTODERMAL, ISOFORM F CIOIN|Ensembl=ENSCING00000002282.3|UniProtKB=F6VF77 F6VF77 PTHR11566:SF212 DYNAMIN DYNAMIN GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;microtubule binding#GO:0008017;ribonucleoside triphosphate phosphatase activity#GO:0017111 localization#GO:0051179;establishment of localization#GO:0051234;receptor internalization#GO:0031623;transport#GO:0006810;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;receptor-mediated endocytosis#GO:0006898;cellular process#GO:0009987;import into cell#GO:0098657 supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;cell periphery#GO:0071944;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;cytoskeleton#GO:0005856;microtubule#GO:0005874;plasma membrane#GO:0005886 membrane traffic protein#PC00150 CIOIN|Ensembl=ENSCING00000004289.3|UniProtKB=F6SI53 F6SI53 PTHR11632:SF51 SUCCINATE DEHYDROGENASE 2 FLAVOPROTEIN SUBUNIT SUCCINATE DEHYDROGENASE [UBIQUINONE] FLAVOPROTEIN SUBUNIT, MITOCHONDRIAL dehydrogenase#PC00092;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000014820.2|UniProtKB=F6S9P0 F6S9P0 PTHR11984:SF53 CONNEXIN GAP JUNCTION PROTEIN wide pore channel activity#GO:0022829;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;channel activity#GO:0015267 biological regulation#GO:0065007;regulation of biological process#GO:0050789;cell communication#GO:0007154;cellular process#GO:0009987;cell-cell signaling#GO:0007267;signaling#GO:0023052 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 cell junction protein#PC00070;gap junction#PC00105 CIOIN|Ensembl=ENSCING00000004427.3|UniProtKB=F6Y437 F6Y437 PTHR12294:SF13 EF HAND DOMAIN FAMILY A1,A2-RELATED MITOCHONDRIAL CALCIUM UPTAKE 3, ISOFORM D cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488 inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;calcium ion transmembrane transport#GO:0070588;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;homeostatic process#GO:0042592;monoatomic cation homeostasis#GO:0055080;inorganic ion transmembrane transport#GO:0098660;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;cellular process#GO:0009987;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;calcium ion transport#GO:0006816;monoatomic ion homeostasis#GO:0050801;localization#GO:0051179;mitochondrial transport#GO:0006839;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation transport#GO:0006812;mitochondrial calcium ion homeostasis#GO:0051560;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion transport#GO:0006811;mitochondrial transmembrane transport#GO:1990542;monoatomic cation transmembrane transport#GO:0098655 envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;transporter complex#GO:1990351;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;calcium channel complex#GO:0034704;membrane#GO:0016020;organelle envelope#GO:0031967;cation channel complex#GO:0034703;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;mitochondrial envelope#GO:0005740;transmembrane transporter complex#GO:1902495;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227;mitochondrial protein-containing complex#GO:0098798 calmodulin-related#PC00061 CIOIN|Ensembl=ENSCING00000008323.3|UniProtKB=F6Q7D4 F6Q7D4 LOC100175786 PTHR22731:SF3 RIBONUCLEASES P/MRP PROTEIN SUBUNIT POP1 RIBONUCLEASES P_MRP PROTEIN SUBUNIT POP1 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;endoribonuclease complex#GO:1902555;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;ribonuclease MRP complex#GO:0000172;catalytic complex#GO:1902494;endonuclease complex#GO:1905348;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;sno(s)RNA-containing ribonucleoprotein complex#GO:0005732;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;ribonuclease P complex#GO:0030677;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 endoribonuclease#PC00094;RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000006318.3|UniProtKB=F6Q4L9 F6Q4L9 PTHR20882:SF14 CYTOPLASMIC TRNA 2-THIOLATION PROTEIN 2 CYTOPLASMIC TRNA 2-THIOLATION PROTEIN 2 transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824;sulfurtransferase activity#GO:0016783 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA modification#GO:0009451;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;tRNA modification#GO:0006400;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;tRNA wobble uridine modification#GO:0002098;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 RNA processing factor#PC00147;RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000007478.3|UniProtKB=F6XWY9 F6XWY9 PTHR12558:SF13 CELL DIVISION CYCLE 16,23,27 CELL DIVISION CYCLE PROTEIN 27 HOMOLOG ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000021571.1|UniProtKB=H2XMQ1 H2XMQ1 PTHR32246:SF173 INGRESSION PROTEIN FIC1 C2 DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000008539.3|UniProtKB=F6YD02 F6YD02 PTHR12277:SF81 ALPHA/BETA HYDROLASE DOMAIN-CONTAINING PROTEIN PROTEIN ABHD13 serine protease#PC00203;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000004674.1|UniProtKB=F6RG94 F6RG94 foxL PTHR11829:SF411 FORKHEAD BOX PROTEIN FORKHEAD BOX PROTEIN L2 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;anatomical structure morphogenesis#GO:0009653;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 CIOIN|Ensembl=ENSCING00000023216.1|UniProtKB=H2XRD5 H2XRD5 LOC100184804 PTHR46005:SF4 RHO GTPASE-ACTIVATING PROTEIN 190 RHO GTPASE-ACTIVATING PROTEIN 190 nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 regulation of anatomical structure size#GO:0090066;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;small GTPase-mediated signal transduction#GO:0007264;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;Rho protein signal transduction#GO:0007266;regulation of cellular component size#GO:0032535;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;regulation of biological quality#GO:0065008;regulation of cell size#GO:0008361;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;intracellular signal transduction#GO:0035556;signaling#GO:0023052 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 GTPase-activating protein#PC00257 PDGF signaling pathway#P00047>Rho#P01174 CIOIN|Ensembl=ENSCING00000021251.1|UniProtKB=H2XXX7 H2XXX7 PTHR23282:SF142 APICAL ENDOSOMAL GLYCOPROTEIN PRECURSOR. MAM DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000020535.1|UniProtKB=H2XXK3 H2XXK3 zf(c2h2)-124 PTHR24379:SF127 KRAB AND ZINC FINGER DOMAIN-CONTAINING BLOODY FINGERS-RELATED sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 CIOIN|Ensembl=ENSCING00000013867.2|UniProtKB=H2XW57 H2XW57 LOC101242389 PTHR45791:SF1 CALCIUM AND INTEGRIN BINDING FAMILY MEMBER 2 CALCIUM AND INTEGRIN BINDING FAMILY MEMBER 1 CIOIN|Ensembl=ENSCING00000008240.3|UniProtKB=F6RDE8 F6RDE8 PTHR46652:SF8 LEUCINE-RICH REPEAT AND IQ DOMAIN-CONTAINING PROTEIN 1-RELATED LEUCINE RICH REPEAT CONTAINING 23 CIOIN|Ensembl=ENSCING00000007045.3|UniProtKB=F6ZC49 F6ZC49 LOC100185233 PTHR11353:SF19 CHAPERONIN T-COMPLEX PROTEIN 1 SUBUNIT THETA protein binding#GO:0005515;unfolded protein binding#GO:0051082;binding#GO:0005488 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein folding#GO:0006457;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;chaperonin-containing T-complex#GO:0005832;protein folding chaperone complex#GO:0101031;intracellular anatomical structure#GO:0005622 chaperonin#PC00073 CIOIN|Ensembl=ENSCING00000009553.3|UniProtKB=F6U8F8 F6U8F8 PTHR15138:SF14 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 4 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 4 nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 cellular aromatic compound metabolic process#GO:0006725;DNA-templated transcription#GO:0006351;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;RNA biosynthetic process#GO:0032774;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;transcription initiation at RNA polymerase II promoter#GO:0006367;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nucleobase-containing compound biosynthetic process#GO:0034654;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;DNA-templated transcription initiation#GO:0006352;aromatic compound biosynthetic process#GO:0019438;transcription by RNA polymerase II#GO:0006366;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;DNA-directed RNA polymerase complex#GO:0000428;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;transcription factor TFIID complex#GO:0005669;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695;RNA polymerase II, holoenzyme#GO:0016591;RNA polymerase complex#GO:0030880;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 RNA metabolism protein#PC00031;general transcription factor#PC00259 General transcription regulation#P00023>TBP-associated factors#P00658;Huntington disease#P00029>TAFII130#P00806;Transcription regulation by bZIP transcription factor#P00055>TBP-associated factors#P01385 CIOIN|Ensembl=ENSCING00000011811.2|UniProtKB=F6Y4G4 F6Y4G4 LOC100179233 PTHR13693:SF102 CLASS II AMINOTRANSFERASE/8-AMINO-7-OXONONANOATE SYNTHASE 2-AMINO-3-KETOBUTYRATE COENZYME A LIGASE, MITOCHONDRIAL transaminase#PC00216;transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000002398.3|UniProtKB=F6QZB5 F6QZB5 LOC100186018 PTHR11203:SF37 CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR FAMILY MEMBER INTEGRATOR COMPLEX SUBUNIT 11 catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a nucleic acid#GO:0140640;endonuclease activity#GO:0004519;RNA nuclease activity#GO:0004540;RNA endonuclease activity#GO:0004521 RNA metabolism protein#PC00031;RNA processing factor#PC00147 CIOIN|Ensembl=ENSCING00000000744.3|UniProtKB=F6Q290 F6Q290 LOC100181020 PTHR35075:SF1 A-KINASE ANCHOR PROTEIN 14 A-KINASE ANCHOR PROTEIN 14 protein kinase A binding#GO:0051018;protein kinase A regulatory subunit binding#GO:0034237;protein binding#GO:0005515;binding#GO:0005488 serine/threonine protein kinase complex#GO:1902554;protein kinase complex#GO:1902911;protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535;catalytic complex#GO:1902494;transferase complex#GO:1990234;transferase complex, transferring phosphorus-containing groups#GO:0061695 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000019510.1|UniProtKB=H2Y089 H2Y089 PTHR13800:SF1 TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL, SUBFAMILY M, MEMBER 6 TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL TRPM monoatomic cation channel activity#GO:0005261;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;monoatomic ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267;monoatomic ion channel activity#GO:0005216;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215 localization#GO:0051179;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;transport#GO:0006810;monoatomic cation transport#GO:0006812;cellular process#GO:0009987;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 CIOIN|Ensembl=ENSCING00000019199.1|UniProtKB=H2XN49 H2XN49 PTHR12966:SF0 NADH DEHYDROGENASE UBIQUINONE 1 ALPHA SUBCOMPLEX SUBUNIT 13 NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 13 envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;respiratory chain complex#GO:0098803;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transporter complex#GO:1990351;oxidoreductase complex#GO:1990204;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;respirasome#GO:0070469;mitochondrial respiratory chain complex I#GO:0005747;protein-containing complex#GO:0032991;mitochondrial envelope#GO:0005740;mitochondrial respirasome#GO:0005746;transmembrane transporter complex#GO:1902495;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227;respiratory chain complex I#GO:0045271;NADH dehydrogenase complex#GO:0030964;mitochondrial protein-containing complex#GO:0098798 dehydrogenase#PC00092;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000003537.3|UniProtKB=F7AYN4 F7AYN4 LOC100187303 PTHR24115:SF600 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF23 pyrophosphatase activity#GO:0016462;cytoskeletal protein binding#GO:0008092;microtubule motor activity#GO:0003777;tubulin binding#GO:0015631;ATP-dependent activity#GO:0140657;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;cytoskeletal motor activity#GO:0003774;microtubule binding#GO:0008017;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;ribonucleoside triphosphate phosphatase activity#GO:0017111;ATP hydrolysis activity#GO:0016887 microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017;cellular process#GO:0009987 supramolecular complex#GO:0099080;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;microtubule#GO:0005874 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 CIOIN|Ensembl=ENSCING00000006186.3|UniProtKB=F6XKA8 F6XKA8 PTHR21290:SF25 SPHINGOMYELIN SYNTHETASE SPHINGOMYELIN SYNTHASE-RELATED PROTEIN 1 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;membrane lipid biosynthetic process#GO:0046467;sphingolipid metabolic process#GO:0006665;primary metabolic process#GO:0044238;ceramide metabolic process#GO:0006672;amide biosynthetic process#GO:0043604;membrane lipid metabolic process#GO:0006643;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;ceramide biosynthetic process#GO:0046513;cellular lipid metabolic process#GO:0044255;amide metabolic process#GO:0043603;sphingolipid biosynthetic process#GO:0030148;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;Golgi membrane#GO:0000139;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 CIOIN|Ensembl=ENSCING00000021687.1|UniProtKB=F6QJA2 F6QJA2 LOC100183557 PTHR10961:SF46 PEROXISOMAL SARCOSINE OXIDASE PEROXISOMAL SARCOSINE OXIDASE oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 oxidase#PC00175;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000006701.3|UniProtKB=F7ART8 F7ART8 LOC100176761 PTHR19857:SF8 MITOCHONDRIAL DIVISION PROTEIN 1-RELATED ANGIO-ASSOCIATED MIGRATORY CELL PROTEIN CIOIN|Ensembl=ENSCING00000003862.3|UniProtKB=F6Y5T0 F6Y5T0 PTHR43223:SF2 ALKYL/ARYL-SULFATASE METALLO-BETA-LACTAMASE DOMAIN-CONTAINING PROTEIN metabolite interconversion enzyme#PC00262;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000014343.2|UniProtKB=F6TZ58 F6TZ58 PTHR24229:SF109 NEUROPEPTIDES RECEPTOR SOMATOSTATIN RECEPTOR TYPE 2-LIKE neuropeptide binding#GO:0042923;signaling receptor activity#GO:0038023;binding#GO:0005488;peptide binding#GO:0042277;amide binding#GO:0033218;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;neuropeptide signaling pathway#GO:0007218;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;neuron projection#GO:0043005;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 CIOIN|Ensembl=ENSCING00000018198.1|UniProtKB=H2Y249 H2Y249 PTHR20003:SF7 GLYCOPROTEIN-RELATED SGNH DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000012836.2|UniProtKB=F6W358 F6W358 LOC100186979 PTHR11214:SF283 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE N-ACETYLLACTOSAMINIDE BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE 4-LIKE transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;protein O-linked glycosylation#GO:0006493;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 bounding membrane of organelle#GO:0098588;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;Golgi membrane#GO:0000139;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111 CIOIN|Ensembl=ENSCING00000007992.3|UniProtKB=F6W3R8 F6W3R8 PTHR11909:SF20 CASEIN KINASE-RELATED CASEIN KINASE I ISOFORM ALPHA transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular process#GO:0009987;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 Wnt signaling pathway#P00057>Casein Kinase 1#P01460;Hedgehog signaling pathway#P00025>Casein kinase I#P00681;Parkinson disease#P00049>Casein kinase I#P01242 CIOIN|Ensembl=ENSCING00000014324.2|UniProtKB=F6TZQ2 F6TZQ2 PTHR10845:SF259 REGULATOR OF G PROTEIN SIGNALING RGS DOMAIN-CONTAINING PROTEIN-RELATED G-protein modulator#PC00022;protein-binding activity modulator#PC00095;GTPase-activating protein#PC00257 CIOIN|Ensembl=ENSCING00000012332.2|UniProtKB=F7ABQ1 F7ABQ1 LOC778980 PTHR23334:SF69 CCAAT/ENHANCER BINDING PROTEIN CCAAT_ENHANCER-BINDING PROTEIN GAMMA sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 DNA-binding transcription factor#PC00218;basic leucine zipper transcription factor#PC00056 CIOIN|Ensembl=ENSCING00000006541.2|UniProtKB=F6RQ08 F6RQ08 LOC100179624 PTHR12197:SF251 HISTONE-LYSINE N-METHYLTRANSFERASE SMYD EG:BACR7C10.4 PROTEIN membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 histone modifying enzyme#PC00261 CIOIN|Ensembl=ENSCING00000018815.1|UniProtKB=H2XXQ7 H2XXQ7 PTHR42904:SF1 NUDIX HYDROLASE, NUDC SUBFAMILY NUCLEOSIDE DIPHOSPHATE-LINKED MOIETY X MOTIF 17 pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;heterocycle catabolic process#GO:0046700;organonitrogen compound catabolic process#GO:1901565;pyridine nucleotide metabolic process#GO:0019362;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;cellular nitrogen compound catabolic process#GO:0044270;phosphate-containing compound metabolic process#GO:0006796;purine-containing compound catabolic process#GO:0072523;organic cyclic compound metabolic process#GO:1901360;purine nucleotide catabolic process#GO:0006195;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;pyridine-containing compound metabolic process#GO:0072524;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;NADP metabolic process#GO:0006739;purine nucleotide metabolic process#GO:0006163;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;nucleoside phosphate catabolic process#GO:1901292;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;nucleotide catabolic process#GO:0009166;nicotinamide nucleotide metabolic process#GO:0046496;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organophosphate catabolic process#GO:0046434;primary metabolic process#GO:0044238;aromatic compound catabolic process#GO:0019439;organic cyclic compound catabolic process#GO:1901361;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;nucleotide metabolic process#GO:0009117;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;microbody#GO:0042579;membrane-bounded organelle#GO:0043227;peroxisome#GO:0005777;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000024638.1|UniProtKB=H2XRE1 H2XRE1 PTHR12847:SF9 ATP-BINDING CASSETTE ABC TRANSPORTER-RELATED NECAP-LIKE PROTEIN CG9132 localization#GO:0051179;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization#GO:0051234;transport#GO:0006810 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;clathrin vesicle coat#GO:0030125;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;vesicle membrane#GO:0012506;organelle#GO:0043226;coated vesicle#GO:0030135;membrane#GO:0016020;vesicle#GO:0031982;vesicle coat#GO:0030120;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;clathrin-coated vesicle#GO:0030136;protein-containing complex#GO:0032991;membrane coat#GO:0030117;coated vesicle membrane#GO:0030662;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;coated membrane#GO:0048475;cytoplasmic vesicle membrane#GO:0030659 ATP-binding cassette (ABC) transporter#PC00003;transporter#PC00227 CIOIN|Ensembl=ENSCING00000014663.2|UniProtKB=F7BHU7 F7BHU7 PTHR24305:SF166 CYTOCHROME P450 CYTOCHROME P450 12A4, MITOCHONDRIAL-RELATED oxygenase#PC00177 CIOIN|Ensembl=ENSCING00000020443.1|UniProtKB=H2Y023 H2Y023 LOC100180300 PTHR46074:SF5 CYSTEINE-RICH PROTEIN CRIP FAMILY MEMBER LIM DOMAIN-CONTAINING PROTEIN C cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 CIOIN|Ensembl=ENSCING00000003320.3|UniProtKB=F6SPA0 F6SPA0 LOC100177824 PTHR24052:SF8 DELTA-RELATED NIMROD A, ISOFORM E cellular anatomical entity#GO:0110165;membrane#GO:0016020 membrane-bound signaling molecule#PC00152 CIOIN|Ensembl=ENSCING00000009229.3|UniProtKB=F6W1I0 F6W1I0 PTHR24343:SF301 SERINE/THREONINE KINASE TESTIS-SPECIFIC SERINE_THREONINE-PROTEIN KINASE 5 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;phosphorylation#GO:0016310;protein phosphorylation#GO:0006468;cellular process#GO:0009987;protein metabolic process#GO:0019538;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000001158.3|UniProtKB=F6YU89 F6YU89 LOC100179568 PTHR46545:SF1 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 51 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 51 CIOIN|Ensembl=ENSCING00000011780.2|UniProtKB=F6SMZ6 F6SMZ6 PTHR22775:SF44 SORTING NEXIN SORTING NEXIN-14 lipid binding#GO:0008289;phosphatidylinositol binding#GO:0035091;phospholipid binding#GO:0005543;binding#GO:0005488 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000000863.3|UniProtKB=F6QVZ9 F6QVZ9 LOC100176290 PTHR44329:SF288 SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 20 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 CIOIN|Gene=CION_CIOIN|UniProtKB=P16240 P16240 PTHR19309:SF0 GASTRIN GASTRIN peptide hormone#PC00179 CCKR signaling map#P06959>G34-Gly#P07036;CCKR signaling map#P06959>G17 - Gly#P07236;CCKR signaling map#P06959>G34#P07190;CCKR signaling map#P06959>Beta-arrestin-1/2#P07187;CCKR signaling map#P06959>G17#P07215 CIOIN|Ensembl=ENSCING00000015264.2|UniProtKB=A0A1W3JBG0 A0A1W3JBG0 LOC100177133 PTHR15184:SF71 ATP SYNTHASE ATP SYNTHASE SUBUNIT BETA, MITOCHONDRIAL ATP synthase#PC00002;primary active transporter#PC00068;transporter#PC00227 ATP synthesis#P02721>F1 beta#P02794 CIOIN|Ensembl=ENSCING00000003290.3|UniProtKB=F6WN06 F6WN06 PTHR35378:SF1 UNNAMED PRODUCT C2H2-TYPE DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000006657.3|UniProtKB=F6U062 F6U062 PTHR19229:SF209 ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA ATP-BINDING CASSETTE SUB-FAMILY A MEMBER 5 ISOFORM X1 transmembrane transporter activity#GO:0022857;primary active transmembrane transporter activity#GO:0015399;ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657;transporter activity#GO:0005215;lipid transporter activity#GO:0005319;active transmembrane transporter activity#GO:0022804 localization#GO:0051179;organic substance transport#GO:0071702;lipid localization#GO:0010876;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;lipid transport#GO:0006869;transport#GO:0006810 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ATP-binding cassette (ABC) transporter#PC00003;transporter#PC00227 CIOIN|Ensembl=ENSCING00000003687.4|UniProtKB=F6WUJ1 F6WUJ1 PTHR43977:SF1 STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 3 STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 3 CIOIN|Ensembl=ENSCING00000020437.1|UniProtKB=H2XPM6 H2XPM6 LOC100182087 PTHR44090:SF1 WD REPEAT-CONTAINING PROTEIN 61 SUPERKILLER COMPLEX PROTEIN 8 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;DNA-directed RNA polymerase complex#GO:0000428;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;intracellular protein-containing complex#GO:0140535;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;transcription elongation factor complex#GO:0008023;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695;RNA polymerase II, holoenzyme#GO:0016591;RNA polymerase complex#GO:0030880;protein-containing complex#GO:0032991;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;Cdc73/Paf1 complex#GO:0016593;nuclear protein-containing complex#GO:0140513 CIOIN|Ensembl=ENSCING00000025091.1|UniProtKB=H2XKU8 H2XKU8 PTHR10605:SF65 HEPARAN SULFATE SULFOTRANSFERASE GH20068P sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824 transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000009034.3|UniProtKB=F6R7B5 F6R7B5 PTHR14240:SF1 RETINITIS PIGMENTOSA GTPASE REGULATOR-INTERACTING PROTEIN PROTEIN FANTOM-RELATED organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;non-motile cilium assembly#GO:1905515;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cell projection organization#GO:0030030;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cilium#GO:0005929;ciliary transition zone#GO:0035869 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000015839.2|UniProtKB=F6SMM7 F6SMM7 PTHR24039:SF58 FIBRILLIN-RELATED EGF-LIKE DOMAIN-CONTAINING PROTEIN extracellular matrix structural protein#PC00103 CIOIN|Ensembl=ENSCING00000005026.3|UniProtKB=F6TX28 F6TX28 PTHR13169:SF0 UBIQUITIN-LIKE PROTEIN 3 HCG-1 PROTEIN UBIQUITIN-LIKE PROTEIN 3 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000021923.1|UniProtKB=H2XVA1 H2XVA1 LOC104265587 PTHR47577:SF1 THAP DOMAIN-CONTAINING PROTEIN 6 THAP DOMAIN-CONTAINING PROTEIN 6 CIOIN|Ensembl=ENSCING00000019152.1|UniProtKB=H2XSA5 H2XSA5 LOC100181225 PTHR11021:SF1 SMALL NUCLEAR RIBONUCLEOPROTEIN F SNRNP-F U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM6 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;RNA processing#GO:0006396;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;mRNA metabolic process#GO:0016071;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;ribosome biogenesis#GO:0042254;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;rRNA metabolic process#GO:0016072;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;ribonucleoprotein complex biogenesis#GO:0022613;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;maturation of SSU-rRNA#GO:0030490;ribosomal small subunit biogenesis#GO:0042274 membrane-enclosed lumen#GO:0031974;supramolecular complex#GO:0099080;U6 snRNP#GO:0005688;organelle lumen#GO:0043233;nucleus#GO:0005634;P-body#GO:0000932;intracellular membrane-bounded organelle#GO:0043231;U4/U6 x U5 tri-snRNP complex#GO:0046540;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;sno(s)RNA-containing ribonucleoprotein complex#GO:0005732;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein complex#GO:1990904;ribonucleoprotein granule#GO:0035770;spliceosomal snRNP complex#GO:0097525;small nuclear ribonucleoprotein complex#GO:0030532;protein-containing complex#GO:0032991;spliceosomal tri-snRNP complex#GO:0097526;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513 RNA splicing factor#PC00148;RNA processing factor#PC00147 CIOIN|Ensembl=ENSCING00000009309.3|UniProtKB=F6UZN8 F6UZN8 PTHR22906:SF43 PROPERDIN PROPERDIN CIOIN|Ensembl=ENSCING00000010142.3|UniProtKB=F6PI67 F6PI67 PTHR15092:SF44 POLY A -SPECIFIC RIBONUCLEASE/TARGET OF EGR1, MEMBER 1 POLY(A)-SPECIFIC RIBONUCLEASE PARN catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;nuclease activity#GO:0004518;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters#GO:0016796;hydrolase activity#GO:0016787;catalytic activity, acting on a nucleic acid#GO:0140640;3'-5'-RNA exonuclease activity#GO:0000175;exonuclease activity#GO:0004527;3'-5' exonuclease activity#GO:0008408;RNA nuclease activity#GO:0004540 negative regulation of gene expression#GO:0010629;regulation of catabolic process#GO:0009894;heterocycle catabolic process#GO:0046700;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulatory ncRNA processing#GO:0070918;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;RNA destabilization#GO:0050779;regulation of biological process#GO:0050789;ncRNA metabolic process#GO:0034660;mRNA metabolic process#GO:0016071;regulation of biological quality#GO:0065008;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;regulation of RNA stability#GO:0043487;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;nuclear-transcribed mRNA poly(A) tail shortening#GO:0000289;positive regulation of mRNA catabolic process#GO:0061014;regulation of cellular process#GO:0050794;post-transcriptional regulation of gene expression#GO:0010608;positive regulation of catabolic process#GO:0009896;mRNA destabilization#GO:0061157;nucleobase-containing compound catabolic process#GO:0034655;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of mRNA stability#GO:0043488;regulation of mRNA catabolic process#GO:0061013;RNA metabolic process#GO:0016070;positive regulation of cellular catabolic process#GO:0031331;RNA processing#GO:0006396;biosynthetic process#GO:0009058;cellular nitrogen compound catabolic process#GO:0044270;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;mRNA catabolic process#GO:0006402;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance catabolic process#GO:1901575;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;regulatory ncRNA-mediated gene silencing#GO:0031047;positive regulation of mRNA metabolic process#GO:1903313;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;RNA 3'-end processing#GO:0031123;cellular biosynthetic process#GO:0044249;nuclear-transcribed mRNA catabolic process#GO:0000956;organic substance biosynthetic process#GO:1901576;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;positive regulation of RNA metabolic process#GO:0051254 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 mRNA polyadenylation factor#PC00146 CIOIN|Ensembl=ENSCING00000018698.1|UniProtKB=H2XMJ0 H2XMJ0 PTHR12307:SF36 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT GLYCOGEN-BINDING SUBUNIT 76A phosphatase binding#GO:0019902;enzyme binding#GO:0019899;protein binding#GO:0005515;protein phosphatase binding#GO:0019903;binding#GO:0005488 protein serine/threonine phosphatase complex#GO:0008287;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical entity#GO:0110165;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622 phosphatase modulator#PC00184 CIOIN|Ensembl=ENSCING00000009043.3|UniProtKB=A0A1W5B9N3 A0A1W5B9N3 LOC100187165 PTHR12307:SF53 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT phosphatase binding#GO:0019902;enzyme binding#GO:0019899;protein binding#GO:0005515;carbohydrate binding#GO:0030246;protein phosphatase binding#GO:0019903;binding#GO:0005488 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of biosynthetic process#GO:0009889;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein serine/threonine phosphatase complex#GO:0008287;cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622 phosphatase modulator#PC00184 CIOIN|Ensembl=ENSCING00000007267.3|UniProtKB=F6U254 F6U254 LOC100184412 PTHR31233:SF6 BICAUDAL D FAMILY MEMBER PROTEIN BICAUDAL D cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;dynein complex binding#GO:0070840 regulation of microtubule-based process#GO:0032886;cellular localization#GO:0051641;macromolecule localization#GO:0033036;regulation of organelle organization#GO:0033043;microtubule cytoskeleton organization#GO:0000226;regulation of cellular component organization#GO:0051128;cellular component organization#GO:0016043;cellular process#GO:0009987;protein localization#GO:0008104;localization#GO:0051179;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of cytoskeleton organization#GO:0051493;cellular macromolecule localization#GO:0070727;microtubule-based process#GO:0007017;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;regulation of microtubule cytoskeleton organization#GO:0070507;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;protein localization to organelle#GO:0033365 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000001850.3|UniProtKB=H2XKX6 H2XKX6 PTHR10822:SF29 GLYPICAN DIVISION ABNORMALLY DELAYED PROTEIN regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of protein localization to membrane#GO:1905475;biological regulation#GO:0065007;regulation of localization#GO:0032879;cell motility#GO:0048870;regulation of cellular localization#GO:0060341;cell migration#GO:0016477;cellular process#GO:0009987;regulation of protein localization#GO:0032880 cell surface#GO:0009986;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000000488.3|UniProtKB=F6YC60 F6YC60 LOC100184330 PTHR24056:SF107 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE 11A-RELATED transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;nitrogen compound metabolic process#GO:0006807;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;regulation of mitotic cell cycle#GO:0007346;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 CIOIN|Ensembl=ENSCING00000014944.2|UniProtKB=F6VKL9 F6VKL9 PTHR44656:SF7 DEHYDROGENASE/REDUCTASE SDR FAMILY MEMBER 12 DEHYDROGENASE_REDUCTASE SDR FAMILY MEMBER 12 dehydrogenase#PC00092;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000024207.1|UniProtKB=H2XPW9 H2XPW9 PTHR19308:SF53 PHOSPHATIDYLCHOLINE TRANSFER PROTEIN CERAMIDE TRANSFER PROTEIN amide transport#GO:0042886;localization#GO:0051179;organic substance transport#GO:0071702;cellular localization#GO:0051641;establishment of localization#GO:0051234;macromolecule localization#GO:0033036;transport#GO:0006810;nitrogen compound transport#GO:0071705;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;lipid localization#GO:0010876;cellular process#GO:0009987;lipid transport#GO:0006869;intracellular lipid transport#GO:0032365 CIOIN|Ensembl=ENSCING00000002840.3|UniProtKB=F6WCM9 F6WCM9 PTHR12596:SF1 EXPORTIN 4,7-RELATED EXPORTIN-4 cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;nitrogen compound transport#GO:0071705;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;nuclear export#GO:0051168;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;protein export from nucleus#GO:0006611;intracellular transport#GO:0046907;nuclear transport#GO:0051169 envelope#GO:0031975;cytoplasm#GO:0005737;nuclear pore#GO:0005643;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear envelope#GO:0005635;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;organelle envelope#GO:0031967;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transporter#PC00227 CIOIN|Ensembl=ENSCING00000006632.3|UniProtKB=F6U1E2 F6U1E2 LOC100177402 PTHR11774:SF11 GERANYLGERANYL TRANSFERASE TYPE BETA SUBUNIT GERANYLGERANYL TRANSFERASE TYPE-2 SUBUNIT BETA acyltransferase#PC00042;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000018645.1|UniProtKB=H2XKZ9 H2XKZ9 PTHR11482:SF6 ARGININE/DIAMINOPIMELATE/ORNITHINE DECARBOXYLASE ORNITHINE DECARBOXYLASE 1-RELATED lyase activity#GO:0016829;carboxy-lyase activity#GO:0016831;carbon-carbon lyase activity#GO:0016830;catalytic activity#GO:0003824 amine metabolic process#GO:0009308;oxoacid metabolic process#GO:0043436;biogenic amine metabolic process#GO:0006576;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;polyamine metabolic process#GO:0006595;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;alpha-amino acid metabolic process#GO:1901605;polyamine biosynthetic process#GO:0006596;carboxylic acid metabolic process#GO:0019752;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 decarboxylase#PC00089 Ornithine degradation#P02758>Ornithine decarboxylase#P03053 CIOIN|Ensembl=ENSCING00000007496.3|UniProtKB=F6XVZ5 F6XVZ5 LOC100186251 PTHR47385:SF25 CALPONIN CALPONIN cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000002563.4|UniProtKB=F6UF57 F6UF57 LOC100182748 PTHR10073:SF12 DNA MISMATCH REPAIR PROTEIN MLH, PMS, MUTL DNA MISMATCH REPAIR PROTEIN MLH1 pyrophosphatase activity#GO:0016462;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ATP hydrolysis activity#GO:0016887;ribonucleoside triphosphate phosphatase activity#GO:0017111 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;mismatch repair#GO:0006298;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;DNA damage response#GO:0006974;response to stress#GO:0006950;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular response to stress#GO:0033554;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622 DNA metabolism protein#PC00009 CIOIN|Ensembl=ENSCING00000010068.3|UniProtKB=F6QD58 F6QD58 PTHR14002:SF59 ENDOGLIN/TGF-BETA RECEPTOR TYPE III CUB AND ZONA PELLUCIDA-LIKE DOMAIN-CONTAINING PROTEIN 1-RELATED transmembrane signal receptor#PC00197 CIOIN|Ensembl=ENSCING00000018640.1|UniProtKB=H2XZ76 H2XZ76 LOC100182896 PTHR12914:SF2 PARTNER OF SLD5 DNA REPLICATION COMPLEX GINS PROTEIN PSF1 cellular aromatic compound metabolic process#GO:0006725;nuclear DNA replication#GO:0033260;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;cell cycle process#GO:0022402;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;mitotic cell cycle process#GO:1903047;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mitotic cell cycle#GO:0000278;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;mitotic DNA replication#GO:1902969;DNA-templated DNA replication#GO:0006261;cell cycle#GO:0007049;DNA replication#GO:0006260;DNA strand elongation involved in DNA replication#GO:0006271;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259;cell cycle DNA replication#GO:0044786 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-DNA complex#GO:0032993;DNA replication preinitiation complex#GO:0031261;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular anatomical structure#GO:0005622;GINS complex#GO:0000811;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 RNA metabolism protein#PC00031;general transcription factor#PC00259 CIOIN|Ensembl=ENSCING00000005607.3|UniProtKB=F7BBQ5 F7BBQ5 PTHR11349:SF91 NUCLEOSIDE DIPHOSPHATE KINASE NUCLEOSIDE DIPHOSPHATE KINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;nucleoside diphosphate kinase activity#GO:0004550;phosphotransferase activity, phosphate group as acceptor#GO:0016776;catalytic activity#GO:0003824;kinase activity#GO:0016301 transferase#PC00220;kinase#PC00137;metabolite interconversion enzyme#PC00262 De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>dTDP kinase#P02919;De novo pyrimidine ribonucleotides biosythesis#P02740>CDP kinase#P02929;De novo pyrimidine ribonucleotides biosythesis#P02740>UDP kinase#P02923;De novo purine biosynthesis#P02738>GDP kinase#P02891;De novo purine biosynthesis#P02738>dADP kinase#P02907;De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>dCDP kinase#P02914;De novo purine biosynthesis#P02738>dGDP kinase#P02889;De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>dUDP kinase#P02912 CIOIN|Ensembl=ENSCING00000024613.1|UniProtKB=H2XSW8 H2XSW8 LOC100177903 PTHR45640:SF26 HEAT SHOCK PROTEIN HSP-12.2-RELATED RE23625P chaperone#PC00072 VEGF signaling pathway#P00056>HSP27#P01412;Angiogenesis#P00005>HSP27#P00231 CIOIN|Ensembl=ENSCING00000020356.1|UniProtKB=H2XSC1 H2XSC1 LOC100183464 PTHR10877:SF183 POLYCYSTIN FAMILY MEMBER AT14535P-RELATED ion channel#PC00133;transporter#PC00227 CIOIN|Ensembl=ENSCING00000006911.3|UniProtKB=F6WAY8 F6WAY8 LOC100187049 PTHR12121:SF100 CARBON CATABOLITE REPRESSOR PROTEIN 4 POLY(A)-SPECIFIC RIBONUCLEASE catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters#GO:0016796;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity#GO:0016787;3'-5'-RNA exonuclease activity#GO:0000175;exonuclease activity#GO:0004527;3'-5' exonuclease activity#GO:0008408;RNA nuclease activity#GO:0004540 mRNA polyadenylation factor#PC00146 CIOIN|Ensembl=ENSCING00000004735.3|UniProtKB=F6PWM6 F6PWM6 PTHR13271:SF47 UNCHARACTERIZED PUTATIVE METHYLTRANSFERASE ACTIN-HISTIDINE N-METHYLTRANSFERASE N-methyltransferase activity#GO:0008170;transferase activity#GO:0016740;catalytic activity#GO:0003824;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;protein-lysine N-methyltransferase activity#GO:0016279;catalytic activity, acting on a protein#GO:0140096;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;lysine N-methyltransferase activity#GO:0016278;protein methyltransferase activity#GO:0008276 macromolecule methylation#GO:0043414;methylation#GO:0032259;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 transferase#PC00220;methyltransferase#PC00155;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000005332.3|UniProtKB=F6TYL9 F6TYL9 LOC100181631 PTHR10138:SF0 TRYPTOPHAN 2,3-DIOXYGENASE TRYPTOPHAN 2,3-DIOXYGENASE oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;dioxygenase activity#GO:0051213;tetrapyrrole binding#GO:0046906;oxidoreductase activity#GO:0016491;heme binding#GO:0020037 cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;heterocycle catabolic process#GO:0046700;biogenic amine metabolic process#GO:0006576;organonitrogen compound catabolic process#GO:1901565;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;cellular nitrogen compound catabolic process#GO:0044270;amino acid catabolic process#GO:0009063;organic cyclic compound metabolic process#GO:1901360;aromatic amino acid metabolic process#GO:0009072;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;alpha-amino acid metabolic process#GO:1901605;purine-containing compound metabolic process#GO:0072521;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;amide metabolic process#GO:0043603;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;amine metabolic process#GO:0009308;acyl-CoA metabolic process#GO:0006637;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;aromatic compound catabolic process#GO:0019439;small molecule catabolic process#GO:0044282;organic cyclic compound catabolic process#GO:1901361;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;carboxylic acid metabolic process#GO:0019752;aromatic amino acid family catabolic process#GO:0009074;amino acid metabolic process#GO:0006520;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 oxygenase#PC00177;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000005344.3|UniProtKB=F7B4V9 F7B4V9 PTHR23389:SF6 CHROMOSOME TRANSMISSION FIDELITY FACTOR 18 REPLICATION FACTOR C SUBUNIT 1 DNA metabolism protein#PC00009 DNA replication#P00017>RFC#P00529 CIOIN|Ensembl=ENSCING00000004884.3|UniProtKB=F6SNI9 F6SNI9 PTHR19305:SF9 SYNAPTOSOMAL ASSOCIATED PROTEIN SYNAPTOSOMAL-ASSOCIATED PROTEIN 29 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 SNARE protein#PC00034 Opioid proenkephalin pathway#P05915>SNARE Complex#P05986;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>SNARE Complex#P01066;Thyrotropin-releasing hormone receptor signaling pathway#P04394>SNARE Complex#P04582;Dopamine receptor mediated signaling pathway#P05912>SNARE Complex#P05956;Adrenaline and noradrenaline biosynthesis#P00001>SNARE#P00072;Beta3 adrenergic receptor signaling pathway#P04379>SNARE Complex#P04447;5HT4 type receptor mediated signaling pathway#P04376>SNARE Complex#P04428;Opioid prodynorphin pathway#P05916>SNARE Complex#P05996;Nicotinic acetylcholine receptor signaling pathway#P00044>SNARE Complex#P01091;5HT3 type receptor mediated signaling pathway#P04375>SNARE Complex#P04423;Ionotropic glutamate receptor pathway#P00037>SNARE Complex#P01013;Metabotropic glutamate receptor group II pathway#P00040>SNARE Complex#P01049;Opioid proopiomelanocortin pathway#P05917>SNARE Complex#P06005;Beta1 adrenergic receptor signaling pathway#P04377>SNARE Complex#P04435;Cortocotropin releasing factor receptor signaling pathway#P04380>SNARE Complex#P04457;Metabotropic glutamate receptor group III pathway#P00039>SNARE Complex#P01042;Oxytocin receptor mediated signaling pathway#P04391>SNARE Complex#P04532;5HT2 type receptor mediated signaling pathway#P04374>SNARE Complex#P04415;5HT1 type receptor mediated signaling pathway#P04373>SNARE Complex#P04405;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>SNARE Complex#P01079;Beta2 adrenergic receptor signaling pathway#P04378>SNARE Complex#P04442 CIOIN|Ensembl=ENSCING00000023722.1|UniProtKB=H2XX32 H2XX32 uglcat2l PTHR10896:SF65 GALACTOSYLGALACTOSYLXYLOSYLPROTEIN 3-BETA-GLUCURONOSYLTRANSFERASE BETA-1,3-GLUCURONYLTRANSFERASE GALACTOSYLGALACTOSYLXYLOSYLPROTEIN 3-BETA-GLUCURONOSYLTRANSFERASE 3 carbohydrate metabolic process#GO:0005975;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;primary metabolic process#GO:0044238 cytoplasm#GO:0005737;bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;Golgi membrane#GO:0000139;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111 CIOIN|Ensembl=ENSCING00000009201.3|UniProtKB=F6WNP2 F6WNP2 LOC100182785 PTHR24300:SF397 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 2U1 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;tetrapyrrole binding#GO:0046906;steroid hydroxylase activity#GO:0008395;oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497;heme binding#GO:0020037 response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;response to chemical#GO:0042221;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 oxygenase#PC00177;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000023209.1|UniProtKB=H2XLC6 H2XLC6 LOC100183554 PTHR11226:SF0 UDP-GLUCOSE GLYCOPROTEIN:GLUCOSYLTRANSFERASE UDP-GLUCOSE:GLYCOPROTEIN GLUCOSYLTRANSFERASE UDP-glucosyltransferase activity#GO:0035251;transferase activity#GO:0016740;unfolded protein binding#GO:0051082;glycosyltransferase activity#GO:0016757;binding#GO:0005488;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194;protein binding#GO:0005515;glucosyltransferase activity#GO:0046527;hexosyltransferase activity#GO:0016758 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule modification#GO:0043412;protein catabolic process#GO:0030163;organonitrogen compound catabolic process#GO:1901565;protein modification process#GO:0036211;biosynthetic process#GO:0009058;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;protein N-linked glycosylation via asparagine#GO:0018279;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;response to organic substance#GO:0010033;macromolecule catabolic process#GO:0009057;cellular response to stimulus#GO:0051716;response to endoplasmic reticulum stress#GO:0034976;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein glycosylation#GO:0006486;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;ERAD pathway#GO:0036503;response to organonitrogen compound#GO:0010243;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;protein N-linked glycosylation#GO:0006487;cellular response to stress#GO:0033554;glycosylation#GO:0070085 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000005066.3|UniProtKB=F6ZM46 F6ZM46 PTHR22984:SF29 SERINE/THREONINE-PROTEIN KINASE PIM SERINE_THREONINE-PROTEIN KINASE PIM-1 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;phosphorylation#GO:0016310;protein phosphorylation#GO:0006468;cellular process#GO:0009987;protein metabolic process#GO:0019538;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000022447.1|UniProtKB=H2XLX9 H2XLX9 PTHR31457:SF2 METHYLMALONIC ACIDURIA AND HOMOCYSTINURIA TYPE C PROTEIN CYANOCOBALAMIN REDUCTASE _ ALKYLCOBALAMIN DEALKYLASE nucleotide binding#GO:0000166;demethylase activity#GO:0032451;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;oxidoreductase activity, acting on metal ions#GO:0016722;nucleoside phosphate binding#GO:1901265;flavin adenine dinucleotide binding#GO:0050660;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167;oxidoreductase activity#GO:0016491 tetrapyrrole metabolic process#GO:0033013;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000009310.3|UniProtKB=A0A1W3JGH5 A0A1W3JGH5 LOC100177652 PTHR11655:SF16 60S/50S RIBOSOMAL PROTEIN L6/L9 60S RIBOSOMAL PROTEIN L9 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cytoplasmic translation#GO:0002181;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic large ribosomal subunit#GO:0022625;large ribosomal subunit#GO:0015934;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000006211.3|UniProtKB=F6YWF1 F6YWF1 PTHR13190:SF1 AUTOPHAGY-RELATED 2, ISOFORM A AUTOPHAGY-RELATED 2, ISOFORM A phosphatidylinositol-3-phosphate binding#GO:0032266;molecular adaptor activity#GO:0060090;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;protein-membrane adaptor activity#GO:0043495;lipid binding#GO:0008289;phosphatidylinositol binding#GO:0035091;phosphatidylinositol phosphate binding#GO:1901981;phospholipid binding#GO:0005543 cellular component assembly#GO:0022607;microautophagy#GO:0016237;cellular component biogenesis#GO:0044085;macroautophagy#GO:0016236;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;autophagy of mitochondrion#GO:0000422;cellular process#GO:0009987;organelle disassembly#GO:1903008;organelle assembly#GO:0070925;process utilizing autophagic mechanism#GO:0061919;cellular component organization or biogenesis#GO:0071840;reticulophagy#GO:0061709;vacuole organization#GO:0007033;cellular component disassembly#GO:0022411;organelle organization#GO:0006996;autophagosome assembly#GO:0000045;catabolic process#GO:0009056;mitochondrion organization#GO:0007005;autophagy#GO:0006914;piecemeal microautophagy of the nucleus#GO:0034727;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;phagophore assembly site#GO:0000407;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000002132.3|UniProtKB=F6WRC9 F6WRC9 LOC100177548 PTHR23403:SF1 TREHALASE TREHALASE hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 carbohydrate catabolic process#GO:0016052;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carbohydrate metabolic process#GO:0005975;organic substance metabolic process#GO:0071704;primary metabolic process#GO:0044238;metabolic process#GO:0008152 CIOIN|Ensembl=ENSCING00000009883.3|UniProtKB=F6ZU53 F6ZU53 PTHR13414:SF9 HUEL-CATION TRANSPORTER PROTON-COUPLED ZINC ANTIPORTER SLC30A9, MITOCHONDRIAL transporter#PC00227 CIOIN|Ensembl=ENSCING00000020054.1|UniProtKB=H2XPR8 H2XPR8 LOC100180784 PTHR37932:SF1 SMALL LYSINE-RICH PROTEIN 1 SMALL LYSINE-RICH PROTEIN 1 CIOIN|Ensembl=ENSCING00000021142.1|UniProtKB=H2XU61 H2XU61 PTHR22973:SF12 LD35087P LD35087P cytoplasm#GO:0005737;bounding membrane of organelle#GO:0098588;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;Golgi membrane#GO:0000139;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000005373.3|UniProtKB=F7BF26 F7BF26 PTHR10416:SF0 DNA POLYMERASE DELTA SUBUNIT 2 DNA POLYMERASE DELTA SUBUNIT 2 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;DNA-templated DNA replication#GO:0006261;DNA replication#GO:0006260;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA strand elongation involved in DNA replication#GO:0006271 DNA polymerase complex#GO:0042575;intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;transferase complex#GO:1990234;transferase complex, transferring phosphorus-containing groups#GO:0061695 DNA-directed DNA polymerase#PC00018;DNA metabolism protein#PC00009 DNA replication#P00017>Pol delta#P00533 CIOIN|Ensembl=ENSCING00000010051.3|UniProtKB=A0A1W5B2W5 A0A1W5B2W5 LOC100183433 PTHR24321:SF8 DEHYDROGENASES, SHORT CHAIN ESTRADIOL 17-BETA-DEHYDROGENASE 8-RELATED dehydrogenase#PC00092;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000020920.1|UniProtKB=H2XZU8 H2XZU8 LOC100175266 PTHR46436:SF1 CENTROSOMAL PROTEIN OF 76 KDA CENTROSOMAL PROTEIN OF 76 KDA CIOIN|Ensembl=ENSCING00000002088.3|UniProtKB=F7AAA7 F7AAA7 PTHR12865:SF1 PHOSPHATIDYLINOSITOL 4-KINASE TYPE-II PHOSPHATIDYLINOSITOL 4-KINASE TYPE 2 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301;lipid kinase activity#GO:0001727 lipid metabolic process#GO:0006629;phospholipid biosynthetic process#GO:0008654;Golgi organization#GO:0007030;organophosphate biosynthetic process#GO:0090407;phosphatidylinositol biosynthetic process#GO:0006661;glycerolipid biosynthetic process#GO:0045017;endomembrane system organization#GO:0010256;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;phosphatidylinositol metabolic process#GO:0046488;glycerophospholipid metabolic process#GO:0006650;cellular component organization#GO:0016043;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;phosphatidylinositol phosphate biosynthetic process#GO:0046854;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;cellular component organization or biogenesis#GO:0071840;endosome organization#GO:0007032;glycerolipid metabolic process#GO:0046486;organelle organization#GO:0006996;glycerophospholipid biosynthetic process#GO:0046474;vesicle organization#GO:0016050;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 trans-Golgi network#GO:0005802;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;organelle subcompartment#GO:0031984;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791;plasma membrane#GO:0005886 kinase#PC00137 CIOIN|Ensembl=ENSCING00000005181.3|UniProtKB=F6RXW9 F6RXW9 PTHR10263:SF5 V-TYPE PROTON ATPASE PROTEOLIPID SUBUNIT V-TYPE PROTON ATPASE 16 KDA PROTEOLIPID SUBUNIT C cellular anatomical entity#GO:0110165;membrane#GO:0016020 ATP synthase#PC00002;primary active transporter#PC00068;transporter#PC00227 CIOIN|Ensembl=ENSCING00000021919.1|UniProtKB=H2XY02 H2XY02 LOC100177734 PTHR15907:SF182 DUF614 FAMILY PROTEIN-RELATED PROTEIN PLANT CADMIUM RESISTANCE 1-RELATED CIOIN|Ensembl=ENSCING00000021308.1|UniProtKB=H2XVA2 H2XVA2 PTHR31655:SF7 PROTEIN FAM78A PROTEIN FAM78A CIOIN|Ensembl=ENSCING00000012612.2|UniProtKB=F6XEJ6 F6XEJ6 PTHR10741:SF2 TRANSLIN AND TRANSLIN ASSOCIATED PROTEIN X TRANSLIN nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000009379.3|UniProtKB=F6WXA3 F6WXA3 PTHR43353:SF5 SUCCINATE-SEMIALDEHYDE DEHYDROGENASE, MITOCHONDRIAL SUCCINATE-SEMIALDEHYDE DEHYDROGENASE, MITOCHONDRIAL nitrogen compound metabolic process#GO:0006807;metabolic process#GO:0008152 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 5-Hydroxytryptamine degredation#P04372>Aldehyde Dehydrogenase#P04402;Aminobutyrate degradation#P02726>Succinate semi-aldehyde dehydrogenase#P02824;Gamma-aminobutyric acid synthesis#P04384>Succinic semialdehyde dehydrogenase#P04481 CIOIN|Ensembl=ENSCING00000024368.1|UniProtKB=H2XKB1 H2XKB1 LOC494358 PTHR11977:SF51 VILLIN PROTEIN FLIGHTLESS-1 HOMOLOG non-motor actin binding protein#PC00165 CIOIN|Ensembl=ENSCING00000006805.3|UniProtKB=F6UN86 F6UN86 PTHR24416:SF564 TYROSINE-PROTEIN KINASE RECEPTOR MACROPHAGE-STIMULATING PROTEIN RECEPTOR signaling receptor activity#GO:0038023;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;molecular transducer activity#GO:0060089;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672;transmembrane signaling receptor activity#GO:0004888 signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;positive regulation of cellular metabolic process#GO:0031325;developmental process#GO:0032502;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;nervous system development#GO:0007399;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;system development#GO:0048731;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;regulation of molecular function#GO:0065009;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;positive regulation of phosphorylation#GO:0042327;cellular response to stimulus#GO:0051716;positive regulation of catalytic activity#GO:0043085;multicellular organism development#GO:0007275;positive regulation of phosphorus metabolic process#GO:0010562;cell communication#GO:0007154;cell motility#GO:0048870;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphate metabolic process#GO:0045937;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;multicellular organismal process#GO:0032501;cell migration#GO:0016477;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 receptor complex#GO:0043235;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 CIOIN|Ensembl=ENSCING00000021245.1|UniProtKB=F6YUL2 F6YUL2 PTHR22988:SF75 MYOTONIC DYSTROPHY S/T KINASE-RELATED MYOSIN-16-LIKE transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;actomyosin structure organization#GO:0031032;cellular component organization#GO:0016043;protein phosphorylation#GO:0006468;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;peptidyl-threonine phosphorylation#GO:0018107;organelle organization#GO:0006996;nitrogen compound metabolic process#GO:0006807;cytoskeleton organization#GO:0007010;phosphorylation#GO:0016310;actin cytoskeleton organization#GO:0030036;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000006206.3|UniProtKB=F6ZE91 F6ZE91 PTHR10374:SF30 LACTOYLGLUTATHIONE LYASE GLYOXALASE I LACTOYLGLUTATHIONE LYASE lyase#PC00144 CIOIN|Ensembl=ENSCING00000014057.2|UniProtKB=F6U2A4 F6U2A4 PTHR12656:SF5 BRG-1 ASSOCIATED FACTOR 250 BAF250 TRITHORAX GROUP PROTEIN OSA nucleosome binding#GO:0031491;protein-containing complex binding#GO:0044877;binding#GO:0005488;chromatin binding#GO:0003682 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of RNA metabolic process#GO:0051254;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;ATPase complex#GO:1904949;intracellular organelle lumen#GO:0070013;SWI/SNF superfamily-type complex#GO:0070603;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;SWI/SNF complex#GO:0016514;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 CIOIN|Ensembl=ENSCING00000009144.3|UniProtKB=F7BBH1 F7BBH1 PTHR43779:SF3 DIOXYGENASE RV0097-RELATED (3R)-3-[(CARBOXYMETHYL)AMINO]FATTY ACID OXYGENASE_DECARBOXYLASE oxygenase#PC00177 CIOIN|Ensembl=ENSCING00000022027.1|UniProtKB=H2XLZ2 H2XLZ2 LOC100175378 PTHR45779:SF7 PEPTIDYLPROLYL ISOMERASE PEPTIDYLPROLYL ISOMERASE TGF-beta signaling pathway#P00052>FKBP12#P01288 CIOIN|Ensembl=ENSCING00000018203.1|UniProtKB=H2XXL3 H2XXL3 LOC100177695 PTHR21207:SF2 PARKIN COREGULATED GENE PROTEIN PARK2 COREGULATED PARKIN COREGULATED GENE PROTEIN heat shock protein binding#GO:0031072;protein binding#GO:0005515;protein-folding chaperone binding#GO:0051087;binding#GO:0005488;Hsp70 protein binding#GO:0030544;Hsp90 protein binding#GO:0051879 CIOIN|Ensembl=ENSCING00000003103.3|UniProtKB=F6PK60 F6PK60 LOC100178272 PTHR17600:SF2 MESODERM DEVELOPMENT CANDIDATE 2 LRP CHAPERONE MESD CIOIN|Ensembl=ENSCING00000023912.1|UniProtKB=H2XKB3 H2XKB3 LOC100177804 PTHR24214:SF38 PDZ AND LIM DOMAIN PROTEIN ZASP PDZ AND LIM DOMAIN PROTEIN ZASP-RELATED cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 CIOIN|Ensembl=ENSCING00000006546.3|UniProtKB=F6RPH7 F6RPH7 LOC100179820 PTHR22776:SF97 MARVEL-CONTAINING POTENTIAL LIPID RAFT-ASSOCIATED PROTEIN RE01453P cellular anatomical entity#GO:0110165;membrane#GO:0016020 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000014383.1|UniProtKB=F7AFN1 F7AFN1 PTHR12137:SF54 CARBOHYDRATE SULFOTRANSFERASE CARBOHYDRATE SULFOTRANSFERASE sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824 transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000010849.3|UniProtKB=F6UAS2 F6UAS2 PTHR42693:SF42 ARYLSULFATASE FAMILY MEMBER ARYLSULFATASE G hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000005989.3|UniProtKB=F6V5T4 F6V5T4 PTHR11119:SF3 XANTHINE-URACIL / VITAMIN C PERMEASE FAMILY MEMBER LD30822P transporter#PC00227 CIOIN|Ensembl=ENSCING00000006141.3|UniProtKB=F6V3N2 F6V3N2 PTHR43391:SF14 RETINOL DEHYDROGENASE-RELATED DEHYDROGENASE_REDUCTASE SDR FAMILY PROTEIN 7-LIKE dehydrogenase#PC00092;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000004024.1|UniProtKB=F6V9V8 F6V9V8 PTHR42972:SF8 TOL-PAL SYSTEM PROTEIN TOLB POLYHYDROXYBUTYRATE DEPOLYMERASE secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000019185.1|UniProtKB=F6WH54 F6WH54 PTHR24418:SF373 TYROSINE-PROTEIN KINASE TYROSINE-PROTEIN KINASE SRC42A protein tyrosine kinase activity#GO:0004713;non-membrane spanning protein tyrosine kinase activity#GO:0004715;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein binding#GO:0005515;catalytic activity, acting on a protein#GO:0140096;signaling receptor binding#GO:0005102;kinase activity#GO:0016301;protein kinase activity#GO:0004672 response to external biotic stimulus#GO:0043207;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;immune response#GO:0006955;developmental process#GO:0032502;cell communication#GO:0007154;cellular process#GO:0009987;defense response to symbiont#GO:0140546;regulation of biological process#GO:0050789;immune system process#GO:0002376;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;cell differentiation#GO:0030154;enzyme-linked receptor protein signaling pathway#GO:0007167;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological process involved in interspecies interaction between organisms#GO:0044419;biological regulation#GO:0065007;innate immune response#GO:0045087;defense response#GO:0006952;signaling#GO:0023052;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169 non-receptor tyrosine protein kinase#PC00168 Parkinson disease#P00049>Src kinase#P01230;Integrin signalling pathway#P00034>Src#P00940 CIOIN|Ensembl=ENSCING00000007573.3|UniProtKB=F6X5E1 F6X5E1 PTHR45628:SF1 VOLTAGE-DEPENDENT CALCIUM CHANNEL TYPE A SUBUNIT ALPHA-1 VOLTAGE-DEPENDENT CALCIUM CHANNEL TYPE D SUBUNIT ALPHA-1 calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;calcium channel activity#GO:0005262;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;transporter activity#GO:0005215;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated calcium channel activity#GO:0005245;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;calcium ion transmembrane transport#GO:0070588;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;calcium ion transport#GO:0006816;localization#GO:0051179;calcium ion import#GO:0070509;import across plasma membrane#GO:0098739;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;calcium ion transmembrane import into cytosol#GO:0097553;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;import into cell#GO:0098657 voltage-gated calcium channel complex#GO:0005891;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;calcium channel complex#GO:0034704;membrane#GO:0016020;cation channel complex#GO:0034703;plasma membrane#GO:0005886 transporter#PC00227;voltage-gated ion channel#PC00241 Beta2 adrenergic receptor signaling pathway#P04378>Ca2+ channel#P04445;Beta1 adrenergic receptor signaling pathway#P04377>Ca2+ channel#P04438;Alzheimer disease-amyloid secretase pathway#P00003>L-type calcium channels#P00082;Oxytocin receptor mediated signaling pathway#P04391>Ca2+ channel#P04535;5HT2 type receptor mediated signaling pathway#P04374>Ca2+ channel#P04411;Nicotinic acetylcholine receptor signaling pathway#P00044>Ca2+ channel#P01096 CIOIN|Ensembl=ENSCING00000005148.3|UniProtKB=F6VAC9 F6VAC9 LOC100176213 PTHR46331:SF2 VALACYCLOVIR HYDROLASE VALACYCLOVIR HYDROLASE hydrolase activity#GO:0016787;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000022287.1|UniProtKB=H2XP85 H2XP85 LOC100182483 PTHR24240:SF223 OPSIN MELATONIN RECEPTOR 1B signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 signal transduction#GO:0007165;response to light stimulus#GO:0009416;cellular response to stimulus#GO:0051716;detection of stimulus#GO:0051606;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;regulation of cellular process#GO:0050794;response to radiation#GO:0009314;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;response to abiotic stimulus#GO:0009628;signaling#GO:0023052;cellular response to light stimulus#GO:0071482 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 CIOIN|Ensembl=ENSCING00000010491.3|UniProtKB=F6SQ32 F6SQ32 PTHR24180:SF45 CYCLIN-DEPENDENT KINASE INHIBITOR 2C-RELATED POLY [ADP-RIBOSE] POLYMERASE TANKYRASE kinase inhibitor#PC00139 CIOIN|Ensembl=ENSCING00000021733.1|UniProtKB=H2XWN2 H2XWN2 PTHR10585:SF14 ER LUMEN PROTEIN RETAINING RECEPTOR ER LUMEN PROTEIN-RETAINING RECEPTOR signal sequence binding#GO:0005048;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277 endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;protein localization to endoplasmic reticulum#GO:0070972;macromolecule localization#GO:0033036;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;protein localization#GO:0008104;localization#GO:0051179;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;maintenance of location#GO:0051235;maintenance of location in cell#GO:0051651;establishment of localization in cell#GO:0051649;protein localization to organelle#GO:0033365;intracellular transport#GO:0046907 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cis-Golgi network#GO:0005801;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 membrane trafficking regulatory protein#PC00151 CIOIN|Ensembl=ENSCING00000003305.3|UniProtKB=F6W1L1 F6W1L1 LOC100177117 PTHR43127:SF1 DEVELOPMENTALLY-REGULATED GTP-BINDING PROTEIN 2 DEVELOPMENTALLY-REGULATED GTP-BINDING PROTEIN 1 carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cytoplasmic translation#GO:0002181;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000002841.3|UniProtKB=F6TX56 F6TX56 PTHR43721:SF36 ELONGATION FACTOR TU-RELATED ELONGATION FACTOR TU, MITOCHONDRIAL nucleic acid binding#GO:0003676;translation regulator activity#GO:0045182;translation regulator activity, nucleic acid binding#GO:0090079;binding#GO:0005488;organic cyclic compound binding#GO:0097159;translation elongation factor activity#GO:0003746;translation factor activity, RNA binding#GO:0008135 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;mitochondrial gene expression#GO:0140053;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;mitochondrial translation#GO:0032543;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;translational elongation#GO:0006414;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 translation elongation factor#PC00222;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000004255.3|UniProtKB=F6YFY0 F6YFY0 PTHR42854:SF3 EUKARYOTIC TRANSLATION INITIATION FACTOR 2 SUBUNIT 3 FAMILY MEMBER EUKARYOTIC TRANSLATION INITIATION FACTOR 2 SUBUNIT 3-RELATED tRNA binding#GO:0000049;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 translation initiation factor#PC00224;translation factor#PC00223;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000018366.1|UniProtKB=H2XV23 H2XV23 PTHR11360:SF316 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER 12-LIKE transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;monocarboxylic acid transmembrane transporter activity#GO:0008028;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215;organic acid transmembrane transporter activity#GO:0005342 localization#GO:0051179;organic substance transport#GO:0071702;monocarboxylic acid transport#GO:0015718;establishment of localization#GO:0051234;organic anion transport#GO:0015711;organic acid transport#GO:0015849;transport#GO:0006810;carboxylic acid transport#GO:0046942 transporter#PC00227 CIOIN|Ensembl=ENSCING00000024616.1|UniProtKB=H2XNX0 H2XNX0 PTHR10749:SF8 PHOSPHORYLASE B KINASE REGULATORY SUBUNIT PHOSPHORYLASE B KINASE REGULATORY SUBUNIT BETA cytoplasm#GO:0005737;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;transferase complex#GO:1990234;serine/threonine protein kinase complex#GO:1902554;protein kinase complex#GO:1902911;cellular anatomical entity#GO:0110165;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622 kinase modulator#PC00140;kinase activator#PC00138 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Phosphorylase b kinase#P00716 CIOIN|Ensembl=ENSCING00000006241.3|UniProtKB=F6PXA1 F6PXA1 LOC100181206 PTHR44366:SF1 UDP-N-ACETYLGLUCOSAMINE--PEPTIDE N-ACETYLGLUCOSAMINYLTRANSFERASE 110 KDA SUBUNIT UDP-N-ACETYLGLUCOSAMINE--PEPTIDE N-ACETYLGLUCOSAMINYLTRANSFERASE 110 KDA SUBUNIT acetylglucosaminyltransferase activity#GO:0008375;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;UDP-glycosyltransferase activity#GO:0008194 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;protein O-linked glycosylation#GO:0006493;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000007757.3|UniProtKB=F6XTN6 F6XTN6 PTHR11616:SF279 SODIUM/CHLORIDE DEPENDENT TRANSPORTER SODIUM-DEPENDENT SEROTONIN TRANSPORTER inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;small molecule binding#GO:0036094;binding#GO:0005488;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;chloride transmembrane transporter activity#GO:0015108;monoatomic cation transmembrane transporter activity#GO:0008324;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;cation binding#GO:0043169;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;organic cyclic compound binding#GO:0097159;metal ion transmembrane transporter activity#GO:0046873;active monoatomic ion transmembrane transporter activity#GO:0022853;heterocyclic compound binding#GO:1901363;monoatomic anion transmembrane transporter activity#GO:0008509;ion binding#GO:0043167;inorganic anion transmembrane transporter activity#GO:0015103;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294 organic hydroxy compound transport#GO:0015850;cellular localization#GO:0051641;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;organic anion transport#GO:0015711;amino acid transport#GO:0006865;organic acid transport#GO:0015849;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;localization#GO:0051179;organic substance transport#GO:0071702;sodium ion transport#GO:0006814;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;neurotransmitter transport#GO:0006836;monoatomic cation transport#GO:0006812;establishment of localization in cell#GO:0051649;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;import into cell#GO:0098657;sodium ion transmembrane transport#GO:0035725 synapse#GO:0045202;neuron projection#GO:0043005;cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886 primary active transporter#PC00068;transporter#PC00227 CIOIN|Ensembl=ENSCING00000019856.1|UniProtKB=H2XVJ5 H2XVJ5 LOC100180074 PTHR11471:SF13 TUMOR NECROSIS FACTOR FAMILY MEMBER TNF FAMILY PROFILE DOMAIN-CONTAINING PROTEIN intercellular signal molecule#PC00207 CIOIN|Ensembl=ENSCING00000017363.2|UniProtKB=F6X1E1 F6X1E1 PTHR13370:SF3 RNA METHYLASE-RELATED TRNA (GUANINE(10)-N2)-METHYLTRANSFERASE HOMOLOG methyltransferase activity#GO:0008168;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031;RNA methyltransferase#PC00033 CIOIN|Ensembl=ENSCING00000009541.3|UniProtKB=F6U9F4 F6U9F4 LOC100186938 PTHR11670:SF54 ACONITASE/IRON-RESPONSIVE ELEMENT FAMILY MEMBER IRON REGULATORY PROTEIN 1A-RELATED carbon-oxygen lyase activity#GO:0016835;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;small molecule binding#GO:0036094;binding#GO:0005488;iron-sulfur cluster binding#GO:0051536;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;hydro-lyase activity#GO:0016836;lyase activity#GO:0016829;mRNA binding#GO:0003729 oxoacid metabolic process#GO:0043436;aerobic respiration#GO:0009060;cellular respiration#GO:0045333;generation of precursor metabolites and energy#GO:0006091;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;carboxylic acid metabolic process#GO:0019752;energy derivation by oxidation of organic compounds#GO:0015980;tricarboxylic acid cycle#GO:0006099;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 Methylcitrate cycle#P02754>Aconitase#P03028 CIOIN|Ensembl=ENSCING00000005998.3|UniProtKB=F6V4K8 F6V4K8 PTHR19932:SF10 WD REPEAT AND HMG-BOX DNA BINDING PROTEIN WD REPEAT AND HMG-BOX DNA-BINDING PROTEIN 1 protein-containing complex binding#GO:0044877;binding#GO:0005488;chromatin binding#GO:0003682 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;DNA damage response#GO:0006974;mitotic cell cycle#GO:0000278;organic cyclic compound metabolic process#GO:1901360;response to stress#GO:0006950;nitrogen compound metabolic process#GO:0006807;DNA-templated DNA replication#GO:0006261;cell cycle#GO:0007049;DNA replication#GO:0006260;cellular response to stress#GO:0033554;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;chromosome#GO:0005694;nuclear replication fork#GO:0043596;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;replication fork#GO:0005657 chromatin/chromatin-binding, or -regulatory protein#PC00077 CIOIN|Ensembl=ENSCING00000007084.3|UniProtKB=H2XYL6 H2XYL6 PTHR10334:SF554 CYSTEINE-RICH SECRETORY PROTEIN-RELATED AT04879P-RELATED extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 defense/immunity protein#PC00090 CIOIN|Ensembl=ENSCING00000024717.1|UniProtKB=H2XUP5 H2XUP5 LOC104266251 PTHR24393:SF163 ZINC FINGER PROTEIN GASTRULA ZINC FINGER PROTEIN XLCGF7.1-LIKE DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 CIOIN|Ensembl=ENSCING00000009936.3|UniProtKB=F6R614 F6R614 LOC100178733 PTHR12879:SF8 SPHINGOLIPID DELTA 4 DESATURASE/C-4 HYDROXYLASE PROTEIN DES2 SPHINGOLIPID DELTA(4)-DESATURASE DES1 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 lipid metabolic process#GO:0006629;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;membrane lipid biosynthetic process#GO:0046467;sphingolipid metabolic process#GO:0006665;ceramide metabolic process#GO:0006672;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;membrane lipid metabolic process#GO:0006643;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;ceramide biosynthetic process#GO:0046513;cellular lipid metabolic process#GO:0044255;amide metabolic process#GO:0043603;sphingolipid biosynthetic process#GO:0030148;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 hydroxylase#PC00122 CIOIN|Ensembl=ENSCING00000016066.2|UniProtKB=F6W5V6 F6W5V6 PTHR10671:SF108 EPITHELIAL MEMBRANE PROTEIN-RELATED CLAUDIN FAMILY PROTEIN-RELATED cytoskeletal protein#PC00085 CIOIN|Ensembl=ENSCING00000009206.3|UniProtKB=F6WNF1 F6WNF1 PTHR34490:SF3 PROTEIN CBG12054-RELATED GALAXIN-LIKE ISOFORM X2 CIOIN|Ensembl=ENSCING00000018603.1|UniProtKB=H2XT29 H2XT29 PTHR21092:SF0 NICASTRIN NICASTRIN macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;protein processing#GO:0016485;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 Notch signaling pathway#P00045>Nicastrin#P01108;Alzheimer disease-presenilin pathway#P00004>Nicastrin#P00115;Alzheimer disease-amyloid secretase pathway#P00003>Nicastrin#P00095 CIOIN|Ensembl=ENSCING00000002265.3|UniProtKB=F6W2K0 F6W2K0 PTHR14790:SF15 RECQ-MEDIATED GENOME INSTABILITY PROTEIN 1 RMI1 RECQ-MEDIATED GENOME INSTABILITY PROTEIN 1 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;double-strand break repair#GO:0006302;nuclear division#GO:0000280;cell cycle process#GO:0022402;nucleobase-containing compound metabolic process#GO:0006139;reciprocal homologous recombination#GO:0140527;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;meiotic cell cycle process#GO:1903046;recombinational repair#GO:0000725;meiosis I cell cycle process#GO:0061982;reproductive process#GO:0022414;reciprocal meiotic recombination#GO:0007131;meiosis I#GO:0007127;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;meiotic cell cycle#GO:0051321;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;double-strand break repair via homologous recombination#GO:0000724;DNA recombination#GO:0006310;resolution of meiotic recombination intermediates#GO:0000712;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;reproduction#GO:0000003;response to stress#GO:0006950;meiotic nuclear division#GO:0140013;organelle organization#GO:0006996;sexual reproduction#GO:0019953;cell cycle#GO:0007049;organelle fission#GO:0048285;homologous recombination#GO:0035825;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear body#GO:0016604;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 CIOIN|Ensembl=ENSCING00000002842.3|UniProtKB=F6WCM2 F6WCM2 LOC100180245 PTHR13072:SF0 DYNACTIN 6 DYNACTIN SUBUNIT 6 protein-containing complex binding#GO:0044877;binding#GO:0005488;dynein complex binding#GO:0070840 cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;mitotic spindle organization#GO:0007052;microtubule-based process#GO:0007017;organelle organization#GO:0006996;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;cell cycle#GO:0007049;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;spindle organization#GO:0007051;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cellular process#GO:0009987;mitotic cell cycle process#GO:1903047 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;microtubule cytoskeleton#GO:0015630;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 CIOIN|Ensembl=ENSCING00000008407.3|UniProtKB=F6XRI7 F6XRI7 LOC100183284 PTHR12096:SF0 NUCLEAR PROTEIN SKIP-RELATED SNW DOMAIN-CONTAINING PROTEIN 1 RNA splicing factor#PC00148;RNA processing factor#PC00147 CIOIN|Ensembl=ENSCING00000019098.1|UniProtKB=H2XW41 H2XW41 PTHR24370:SF10 OPTICIN LEUCINE-RICH REPEAT AND WD REPEAT-CONTAINING PROTEIN 1 extracellular matrix protein#PC00102 CIOIN|Ensembl=ENSCING00000003314.3|UniProtKB=F6SPK3 F6SPK3 PTHR43721:SF9 ELONGATION FACTOR TU-RELATED GTP-BINDING PROTEIN 1 nucleic acid binding#GO:0003676;translation regulator activity#GO:0045182;translation regulator activity, nucleic acid binding#GO:0090079;binding#GO:0005488;organic cyclic compound binding#GO:0097159;translation elongation factor activity#GO:0003746;translation factor activity, RNA binding#GO:0008135 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;translational elongation#GO:0006414;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 translation elongation factor#PC00222;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000008632.4|UniProtKB=F6ZZ40 F6ZZ40 PTHR10676:SF36 DYNEIN HEAVY CHAIN FAMILY PROTEIN DYNEIN HEAVY CHAIN AT 93AB, ISOFORM C cytoskeletal motor activity#GO:0003774;microtubule motor activity#GO:0003777;protein binding#GO:0005515;ATP-dependent activity#GO:0140657;binding#GO:0005488 cilium-dependent cell motility#GO:0060285;microtubule-based process#GO:0007017;cilium or flagellum-dependent cell motility#GO:0001539;microtubule-based movement#GO:0007018;cell motility#GO:0048870;cellular process#GO:0009987;cilium movement involved in cell motility#GO:0060294;cilium movement#GO:0003341 axoneme#GO:0005930;catalytic complex#GO:1902494;cytoplasmic region#GO:0099568;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;microtubule associated complex#GO:0005875;non-membrane-bounded organelle#GO:0043228;motile cilium#GO:0031514;protein-containing complex#GO:0032991;9+2 motile cilium#GO:0097729;microtubule cytoskeleton#GO:0015630;ciliary plasm#GO:0097014;plasma membrane bounded cell projection cytoplasm#GO:0032838;membrane-bounded organelle#GO:0043227;dynein complex#GO:0030286;cell projection#GO:0042995;cytoskeleton#GO:0005856;cilium#GO:0005929 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 Huntington disease#P00029>Dynein complex#P00774 CIOIN|Ensembl=ENSCING00000014345.2|UniProtKB=F6TYX5 F6TYX5 LOC100175951 PTHR24006:SF733 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE RE52890P cysteine-type peptidase activity#GO:0008234;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;cysteine-type deubiquitinase activity#GO:0004843 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;protein modification by small protein removal#GO:0070646;protein deubiquitination#GO:0016579;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;post-translational protein modification#GO:0043687;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cysteine protease#PC00081;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000015395.2|UniProtKB=F6XWK4 F6XWK4 PTHR11695:SF294 ALCOHOL DEHYDROGENASE RELATED RETICULON-4-INTERACTING PROTEIN 1, MITOCHONDRIAL dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000003206.3|UniProtKB=Q4VYB1 Q4VYB1 uglcat1 PTHR10896:SF65 GALACTOSYLGALACTOSYLXYLOSYLPROTEIN 3-BETA-GLUCURONOSYLTRANSFERASE BETA-1,3-GLUCURONYLTRANSFERASE GALACTOSYLGALACTOSYLXYLOSYLPROTEIN 3-BETA-GLUCURONOSYLTRANSFERASE 3 carbohydrate metabolic process#GO:0005975;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;primary metabolic process#GO:0044238 cytoplasm#GO:0005737;bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;Golgi membrane#GO:0000139;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111 CIOIN|Ensembl=ENSCING00000013463.2|UniProtKB=F6SDX4 F6SDX4 PTHR19444:SF13 UNC-93 RELATED PROTEIN UNC-93 HOMOLOG A membrane-bound signaling molecule#PC00152 CIOIN|Ensembl=ENSCING00000001296.3|UniProtKB=F6WWL5 F6WWL5 erk3_4 PTHR24055:SF490 MITOGEN-ACTIVATED PROTEIN KINASE PROTEIN KINASE DOMAIN-CONTAINING PROTEIN transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;signaling#GO:0023052 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000006180.3|UniProtKB=F7BK44 F7BK44 LOC100175151 PTHR12146:SF0 40S RIBOSOMAL PROTEIN S10 RIBOSOMAL PROTEIN S10 structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;structural molecule activity#GO:0005198;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic small ribosomal subunit#GO:0022627;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;small ribosomal subunit#GO:0015935;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;ribosomal subunit#GO:0044391 ribosomal protein#PC00202;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000008058.3|UniProtKB=F7BCV4 F7BCV4 LOC100184456 PTHR43380:SF1 2-OXOISOVALERATE DEHYDROGENASE SUBUNIT ALPHA, MITOCHONDRIAL 2-OXOISOVALERATE DEHYDROGENASE SUBUNIT ALPHA, MITOCHONDRIAL oxoacid metabolic process#GO:0043436;branched-chain amino acid metabolic process#GO:0009081;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;amino acid catabolic process#GO:0009063;small molecule catabolic process#GO:0044282;nitrogen compound metabolic process#GO:0006807;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;carboxylic acid metabolic process#GO:0019752;amino acid metabolic process#GO:0006520;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 dehydrogenase#PC00092;oxidoreductase#PC00176 Pyruvate metabolism#P02772>Pyruvate Dehydrogenase#P03133 CIOIN|Ensembl=ENSCING00000007349.3|UniProtKB=F6XXW0 F6XXW0 PTHR48013:SF15 DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 5-RELATED DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 4 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;MAPK cascade#GO:0000165;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;cellular process#GO:0009987;signaling#GO:0023052 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Integrin signalling pathway#P00034>Jnk#P00951;FAS signaling pathway#P00020>MKK4#P00610;p38 MAPK pathway#P05918>MKK4#P06034;Huntington disease#P00029>MAPKK4#P00787;Ras Pathway#P04393>MKK4/7#P04565;Gonadotropin-releasing hormone receptor pathway#P06664>MKK4/7#P06760;Huntington disease#P00029>SEK-1#P00792;Apoptosis signaling pathway#P00006>SEK1#P00266;Angiogenesis#P00005>JNKK1#P00199;Toll receptor signaling pathway#P00054>MKK4#P01366;FGF signaling pathway#P00021>MKK4,7#P00637;Integrin signalling pathway#P00034>MEK#P00925;EGF receptor signaling pathway#P00018>MKK4,7#P00555;Oxidative stress response#P00046>MKK4#P01138;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>MEK#P00891 CIOIN|Ensembl=ENSCING00000025136.1|UniProtKB=H2XN98 H2XN98 PTHR12929:SF10 SOLUTE CARRIER FAMILY 52 RIBOFLAVIN TRANSPORTER transmembrane transporter activity#GO:0022857;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215 localization#GO:0051179;vitamin transport#GO:0051180;nitrogen compound transport#GO:0071705;organic substance transport#GO:0071702;establishment of localization#GO:0051234;organic anion transport#GO:0015711;transport#GO:0006810 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000007479.3|UniProtKB=F6XWW8 F6XWW8 PTHR11082:SF5 TRNA-DIHYDROURIDINE SYNTHASE TRNA-DIHYDROURIDINE(16_17) SYNTHASE [NAD(P)(+)]-LIKE catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on RNA#GO:0140098;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor#GO:0016628 RNA processing factor#PC00147 CIOIN|Ensembl=ENSCING00000024107.1|UniProtKB=H2Y1Z9 H2Y1Z9 LOC100185883 PTHR11777:SF9 ALANYL-TRNA SYNTHETASE ALANINE--TRNA LIGASE, CYTOPLASMIC catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;ligase activity#GO:0016874;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;peptide biosynthetic process#GO:0043043;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 aminoacyl-tRNA synthetase#PC00047;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000008842.3|UniProtKB=F7BKM3 F7BKM3 PTHR23101:SF122 RAB GDP/GTP EXCHANGE FACTOR RABAPTIN-5-ASSOCIATED EXCHANGE FACTOR FOR RAB5 nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;binding#GO:0005488;molecular function regulator activity#GO:0098772;enzyme binding#GO:0019899;protein binding#GO:0005515;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;guanyl-nucleotide exchange factor activity#GO:0005085 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;endocytic vesicle#GO:0030139;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 CIOIN|Ensembl=ENSCING00000019139.1|UniProtKB=H2XKW4 H2XKW4 PTHR24372:SF77 GLYCOPROTEIN HORMONE RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 response to organic substance#GO:0010033;positive regulation of adenylate cyclase activity#GO:0045762;regulation of lyase activity#GO:0051339;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;cellular response to stimulus#GO:0051716;regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;cellular response to endogenous stimulus#GO:0071495;cellular response to chemical stimulus#GO:0070887;positive regulation of catalytic activity#GO:0043085;cellular response to organic substance#GO:0071310;regulation of cyclase activity#GO:0031279;positive regulation of molecular function#GO:0044093;cell communication#GO:0007154;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;positive regulation of cyclase activity#GO:0031281;hormone-mediated signaling pathway#GO:0009755;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to endogenous stimulus#GO:0009719;response to hormone#GO:0009725;cellular response to hormone stimulus#GO:0032870;response to chemical#GO:0042221;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of lyase activity#GO:0051349;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 CIOIN|Ensembl=ENSCING00000021680.1|UniProtKB=H2XVM6 H2XVM6 LOC100180686 PTHR47437:SF4 JNK-INTERACTING PROTEIN 1-LIKE PROTEIN JNK-INTERACTING PROTEIN 1-LIKE PROTEIN molecular adaptor activity#GO:0060090;signaling adaptor activity#GO:0035591;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;protein binding#GO:0005515;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;kinase binding#GO:0019900 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;MAPK cascade#GO:0000165;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;cellular process#GO:0009987;JNK cascade#GO:0007254;signaling#GO:0023052 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000014115.2|UniProtKB=F6WWQ0 F6WWQ0 LOC100182487 PTHR24412:SF497 KELCH PROTEIN KELCH-LIKE PROTEIN 18 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000005946.3|UniProtKB=F6YY38 F6YY38 PTHR24025:SF28 DESMOGLEIN FAMILY MEMBER PUTATIVE-RELATED cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488 cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987 cell junction#GO:0030054;cellular anatomical entity#GO:0110165;cell-cell junction#GO:0005911;anchoring junction#GO:0070161 cell adhesion molecule#PC00069;cadherin#PC00057 CIOIN|Ensembl=ENSCING00000014637.2|UniProtKB=F6SAB4 F6SAB4 LOC100180631 PTHR33802:SF1 SI:CH211-161H7.5-RELATED XK-RELATED PROTEIN CIOIN|Ensembl=ENSCING00000007571.3|UniProtKB=F7AMB6 F7AMB6 LOC100186774 PTHR35190:SF2 PROTEIN DCD1B PROTEIN DCD1B CIOIN|Ensembl=ENSCING00000000742.3|UniProtKB=F6Q1K9 F6Q1K9 LOC100178560 PTHR24024:SF19 PULMONARY SURFACTANT-ASSOCIATED PROTEIN A FARMER, ISOFORM H extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 surfactant#PC00212;structural protein#PC00211 CIOIN|Ensembl=ENSCING00000022321.1|UniProtKB=H2XM61 H2XM61 PTHR23320:SF165 MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MS4A -RELATED MARVEL DOMAIN-CONTAINING PROTEIN transporter#PC00227 CIOIN|Ensembl=ENSCING00000001659.3|UniProtKB=F6YIB7 F6YIB7 PTHR12358:SF112 SPHINGOSINE KINASE LD11247P-RELATED transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301;lipid kinase activity#GO:0001727 organic hydroxy compound metabolic process#GO:1901615;lipid metabolic process#GO:0006629;alcohol biosynthetic process#GO:0046165;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic hydroxy compound biosynthetic process#GO:1901617;alcohol metabolic process#GO:0006066;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;membrane lipid biosynthetic process#GO:0046467;sphingolipid metabolic process#GO:0006665;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;membrane lipid metabolic process#GO:0006643;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;phosphorylation#GO:0016310;small molecule biosynthetic process#GO:0044283;cellular lipid metabolic process#GO:0044255;sphingolipid biosynthetic process#GO:0030148;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;membrane#GO:0016020;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 kinase#PC00137 CIOIN|Ensembl=ENSCING00000012112.2|UniProtKB=F6V921 F6V921 PTHR19969:SF8 SH2-SH3 ADAPTOR PROTEIN-RELATED ADAPTER MOLECULE CRK molecular adaptor activity#GO:0060090;signaling adaptor activity#GO:0035591;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;protein tyrosine kinase binding#GO:1990782;receptor tyrosine kinase binding#GO:0030971;signaling receptor binding#GO:0005102;kinase binding#GO:0019900 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cell motility#GO:0048870;cellular process#GO:0009987;cell migration#GO:0016477;signaling#GO:0023052 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 Integrin signalling pathway#P00034>Crk#P00933;CCKR signaling map#P06959>CRK#P07125;Angiogenesis#P00005>Crk#P00207 CIOIN|Ensembl=ENSCING00000008676.3|UniProtKB=F6XMJ7 F6XMJ7 LOC100178717 PTHR11785:SF512 AMINO ACID TRANSPORTER SOBREMESA, ISOFORM B L-amino acid transmembrane transporter activity#GO:0015179;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;amino acid transmembrane transporter activity#GO:0015171;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215;organic acid transmembrane transporter activity#GO:0005342 localization#GO:0051179;organic substance transport#GO:0071702;amino acid transmembrane transport#GO:0003333;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;amino acid transport#GO:0006865;organic anion transport#GO:0015711;organic acid transport#GO:0015849;transport#GO:0006810;nitrogen compound transport#GO:0071705;organic acid transmembrane transport#GO:1903825;carboxylic acid transport#GO:0046942;cellular process#GO:0009987;carboxylic acid transmembrane transport#GO:1905039 transporter#PC00227 CIOIN|Ensembl=ENSCING00000010797.3|UniProtKB=F6XKI3 F6XKI3 PTHR24256:SF545 TRYPTASE-RELATED INACTIVE SERINE PROTEASE 54 hydrolase activity#GO:0016787;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 serine protease#PC00203;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000010151.3|UniProtKB=F6PI29 F6PI29 LOC100177372 PTHR23259:SF70 RIDDLE ACCESSORY GLAND PROTEIN ACP62F-RELATED protease inhibitor#PC00191;protein-binding activity modulator#PC00095 CIOIN|Ensembl=ENSCING00000007654.3|UniProtKB=F6VWV8 F6VWV8 PTHR43184:SF12 MAJOR FACILITATOR SUPERFAMILY TRANSPORTER 16, ISOFORM B SUGAR PHOSPHATE EXCHANGER 3 transporter#PC00227 CIOIN|Ensembl=ENSCING00000001426.3|UniProtKB=F6YRT2 F6YRT2 LOC100182702 PTHR11645:SF58 PYRROLINE-5-CARBOXYLATE REDUCTASE NADP-DEPENDENT OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN 1 oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;proteinogenic amino acid metabolic process#GO:0170039;heterocycle metabolic process#GO:0046483;proteinogenic amino acid biosynthetic process#GO:0170038;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;organic cyclic compound metabolic process#GO:1901360;alpha-amino acid biosynthetic process#GO:1901607;nitrogen compound metabolic process#GO:0006807;amino acid biosynthetic process#GO:0008652;alpha-amino acid metabolic process#GO:1901605;small molecule biosynthetic process#GO:0044283;L-amino acid biosynthetic process#GO:0170034;carboxylic acid metabolic process#GO:0019752;L-amino acid metabolic process#GO:0170033;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 reductase#PC00198;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000023035.1|UniProtKB=H2XLI6 H2XLI6 PTHR12011:SF471 ADHESION G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 2 PROFILE 2 DOMAIN-CONTAINING PROTEIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 CIOIN|Ensembl=ENSCING00000009102.3|UniProtKB=F6Q9D5 F6Q9D5 PTHR10340:SF34 SPHINGOMYELIN PHOSPHODIESTERASE SPHINGOMYELIN PHOSPHODIESTERASE hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphoric diester hydrolase activity#GO:0008081;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 phosphodiesterase#PC00185;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000007986.3|UniProtKB=F7ATJ8 F7ATJ8 PTHR10159:SF530 DUAL SPECIFICITY PROTEIN PHOSPHATASE DUAL SPECIFICITY PROTEIN PHOSPHATASE DDB_G0271350-RELATED hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 regulation of MAPK cascade#GO:0043408;negative regulation of biological process#GO:0048519;macromolecule modification#GO:0043412;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;protein modification process#GO:0036211;regulation of intracellular signal transduction#GO:1902531;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;negative regulation of MAPK cascade#GO:0043409;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of cell communication#GO:0010646;negative regulation of response to stimulus#GO:0048585;macromolecule metabolic process#GO:0043170;negative regulation of signaling#GO:0023057;cellular metabolic process#GO:0044237;protein dephosphorylation#GO:0006470;organonitrogen compound metabolic process#GO:1901564;cellular process#GO:0009987;primary metabolic process#GO:0044238;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;dephosphorylation#GO:0016311;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 protein phosphatase#PC00195;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000005362.3|UniProtKB=F7BFG7 F7BFG7 PTHR13138:SF3 PROTEIN LIN1 CD2 ANTIGEN CYTOPLASMIC TAIL-BINDING PROTEIN 2 ribonucleoprotein complex#GO:1990904;spliceosomal snRNP complex#GO:0097525;small nuclear ribonucleoprotein complex#GO:0030532;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;Sm-like protein family complex#GO:0120114;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;U5 snRNP#GO:0005682;intracellular anatomical structure#GO:0005622 RNA splicing factor#PC00148;RNA processing factor#PC00147;RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000012177.2|UniProtKB=F6TUQ2 F6TUQ2 LOC100182627 PTHR13439:SF0 CT120 PROTEIN TOPOISOMERASE I DAMAGE AFFECTED PROTEIN 4 lipid homeostasis#GO:0055088;homeostatic process#GO:0042592;chemical homeostasis#GO:0048878 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000002569.4|UniProtKB=F6UF11 F6UF11 PTHR23506:SF13 GH10249P VESICULAR ACETYLCHOLINE TRANSPORTER transmembrane transporter activity#GO:0022857;organic cation transmembrane transporter activity#GO:0015101;transporter activity#GO:0005215 regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;anterograde trans-synaptic signaling#GO:0098916;biological regulation#GO:0065007;trans-synaptic signaling#GO:0099537;synaptic signaling#GO:0099536;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052;cell-cell signaling#GO:0007267 bounding membrane of organelle#GO:0098588;synapse#GO:0045202;intracellular membrane-bounded organelle#GO:0043231;plasma membrane protein complex#GO:0098797;terminal bouton#GO:0043195;clathrin vesicle coat#GO:0030125;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;AP-type membrane coat adaptor complex#GO:0030119;transport vesicle membrane#GO:0030658;clathrin-coated vesicle#GO:0030136;axon terminus#GO:0043679;membrane coat#GO:0030117;neuron projection terminus#GO:0044306;distal axon#GO:0150034;coated membrane#GO:0048475;cytoplasmic vesicle membrane#GO:0030659;cell projection#GO:0042995;trans-Golgi network transport vesicle#GO:0030140;clathrin-coated pit#GO:0005905;membrane protein complex#GO:0098796;presynapse#GO:0098793;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;cell junction#GO:0030054;cell periphery#GO:0071944;coated vesicle#GO:0030135;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;vesicle coat#GO:0030120;axon#GO:0030424;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;Golgi-associated vesicle membrane#GO:0030660;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;coated vesicle membrane#GO:0030662;neuron projection#GO:0043005;Golgi-associated vesicle#GO:0005798;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;transport vesicle#GO:0030133;endocytic vesicle#GO:0030139;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;transporter#PC00227 Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>VAChT#P01078;Nicotinic acetylcholine receptor signaling pathway#P00044>VAChT#P01089;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>VAChT#P01065 CIOIN|Ensembl=ENSCING00000011840.2|UniProtKB=F6ZL64 F6ZL64 LOC100182577 PTHR12770:SF31 RUS1 FAMILY PROTEIN C16ORF58 RUS FAMILY MEMBER 1 CIOIN|Ensembl=ENSCING00000012505.2|UniProtKB=F6S5T2 F6S5T2 zf(c2h2)-116 PTHR24403:SF105 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 2-LIKE ISOFORM X1 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of RNA metabolic process#GO:0051254;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 CIOIN|Ensembl=ENSCING00000009885.3|UniProtKB=F6RAU8 F6RAU8 LOC100185683 PTHR24390:SF244 ZINC FINGER PROTEIN LD33778P-RELATED sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 CIOIN|Ensembl=ENSCING00000014732.2|UniProtKB=F6WVN4 F6WVN4 PTHR14969:SF28 SPHINGOSINE-1-PHOSPHATE PHOSPHOHYDROLASE DIHYDROSPHINGOSINE 1-PHOSPHATE PHOSPHATASE LCB3-RELATED hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;phosphatase#PC00181;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000014916.2|UniProtKB=F6Y7J1 F6Y7J1 LOC100181119 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE SSU-1 sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824 cellular metabolic process#GO:0044237;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000019056.1|UniProtKB=H2XZB1 H2XZB1 PTHR24246:SF27 OLFACTORY RECEPTOR AND ADENOSINE RECEPTOR ADENOSINE RECEPTOR, ISOFORM A G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711 CIOIN|Ensembl=ENSCING00000021869.1|UniProtKB=H2XK34 H2XK34 PTHR23043:SF17 HYPOXIA-INDUCIBLE FACTOR 1 ALPHA PROTEIN SIMILAR basic helix-loop-helix transcription factor#PC00055 CIOIN|Ensembl=ENSCING00000003143.3|UniProtKB=F6R6F3 F6R6F3 PTHR22988:SF73 MYOTONIC DYSTROPHY S/T KINASE-RELATED RHO-ASSOCIATED PROTEIN KINASE transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cell division#GO:0051301;signal transduction#GO:0007165;small GTPase-mediated signal transduction#GO:0007264;macromolecule modification#GO:0043412;developmental process#GO:0032502;cell cycle process#GO:0022402;protein modification process#GO:0036211;regulation of cellular component organization#GO:0051128;peptidyl-amino acid modification#GO:0018193;mitotic cell cycle process#GO:1903047;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;mitotic cytokinesis#GO:0000281;mitotic cell cycle#GO:0000278;actin filament-based process#GO:0030029;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;regulation of cellular component biogenesis#GO:0044087;cytoskeleton-dependent cytokinesis#GO:0061640;cytoskeleton organization#GO:0007010;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;protein metabolic process#GO:0019538;cytokinesis#GO:0000910;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cell communication#GO:0007154;actomyosin structure organization#GO:0031032;cellular component organization#GO:0016043;cellular process#GO:0009987;Rho protein signal transduction#GO:0007266;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;embryo development#GO:0009790;peptidyl-threonine phosphorylation#GO:0018107;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cortical cytoskeleton organization#GO:0030865;biological regulation#GO:0065007;cell cycle#GO:0007049;multicellular organismal process#GO:0032501;regulation of cell junction assembly#GO:1901888;actin cytoskeleton organization#GO:0030036;embryonic morphogenesis#GO:0048598;cortical actin cytoskeleton organization#GO:0030866 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Cytoskeletal regulation by Rho GTPase#P00016>ROCK#P00519 CIOIN|Ensembl=ENSCING00000023728.1|UniProtKB=H2XUE3 H2XUE3 LOC100179585 PTHR11599:SF16 PROTEASOME SUBUNIT ALPHA/BETA PROTEASOME SUBUNIT ALPHA TYPE-2 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 peptidase complex#GO:1905368;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;proteasome complex#GO:0000502;endopeptidase complex#GO:1905369;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 protease#PC00190;protein modifying enzyme#PC00260 Parkinson disease#P00049>20S proteasome#P01227 CIOIN|Ensembl=ENSCING00000016716.2|UniProtKB=F7A9X4 F7A9X4 PTHR11785:SF512 AMINO ACID TRANSPORTER SOBREMESA, ISOFORM B L-amino acid transmembrane transporter activity#GO:0015179;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;amino acid transmembrane transporter activity#GO:0015171;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215;organic acid transmembrane transporter activity#GO:0005342 localization#GO:0051179;organic substance transport#GO:0071702;amino acid transmembrane transport#GO:0003333;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;amino acid transport#GO:0006865;organic anion transport#GO:0015711;organic acid transport#GO:0015849;transport#GO:0006810;nitrogen compound transport#GO:0071705;organic acid transmembrane transport#GO:1903825;carboxylic acid transport#GO:0046942;cellular process#GO:0009987;carboxylic acid transmembrane transport#GO:1905039 transporter#PC00227 CIOIN|Ensembl=ENSCING00000009516.3|UniProtKB=F6XC20 F6XC20 cagf9 PTHR45781:SF1 AGAP000281-PA HMG BOX DOMAIN-CONTAINING PROTEIN nucleic acid binding#GO:0003676;protein-containing complex binding#GO:0044877;chromatin DNA binding#GO:0031490;binding#GO:0005488;organic cyclic compound binding#GO:0097159;chromatin binding#GO:0003682;DNA binding#GO:0003677 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 HMG box transcription factor#PC00024 CIOIN|Ensembl=ENSCING00000002710.3|UniProtKB=F6UDK5 F6UDK5 LOC100183039 PTHR19384:SF76 NITRIC OXIDE SYNTHASE-RELATED NITRIC OXIDE SYNTHASE carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;oxidoreductase activity, acting on NAD(P)H#GO:0016651;oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497;organic cyclic compound binding#GO:0097159;oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor#GO:0016653;nucleoside phosphate binding#GO:1901265;flavin adenine dinucleotide binding#GO:0050660;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen#GO:0016709 response to external biotic stimulus#GO:0043207;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;response to biotic stimulus#GO:0009607;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;alpha-amino acid metabolic process#GO:1901605;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;response to molecule of bacterial origin#GO:0002237;carboxylic acid catabolic process#GO:0046395;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;oxoacid metabolic process#GO:0043436;regulation of lyase activity#GO:0051339;response to oxygen-containing compound#GO:1901700;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;organic acid metabolic process#GO:0006082;response to lipopolysaccharide#GO:0032496;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;positive regulation of phosphate metabolic process#GO:0045937;regulation of cellular process#GO:0050794;regulation of metabolic process#GO:0019222;small molecule metabolic process#GO:0044281;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;regulation of cyclase activity#GO:0031279;positive regulation of molecular function#GO:0044093;organonitrogen compound catabolic process#GO:1901565;response to lipid#GO:0033993;biosynthetic process#GO:0009058;regulation of catalytic activity#GO:0050790;positive regulation of biosynthetic process#GO:0009891;response to endogenous stimulus#GO:0009719;amino acid catabolic process#GO:0009063;positive regulation of metabolic process#GO:0009893;response to bacterium#GO:0009617;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;L-amino acid metabolic process#GO:0170033;signaling#GO:0023052;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;response to organic substance#GO:0010033;proteinogenic amino acid metabolic process#GO:0170039;cellular response to stimulus#GO:0051716;positive regulation of catalytic activity#GO:0043085;arginine metabolic process#GO:0006525;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;positive regulation of cyclase activity#GO:0031281;regulation of primary metabolic process#GO:0080090;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;response to hormone#GO:0009725;regulation of cellular biosynthetic process#GO:0031326;response to chemical#GO:0042221;regulation of nucleobase-containing compound metabolic process#GO:0019219;response to other organism#GO:0051707;biological process involved in interspecies interaction between organisms#GO:0044419;biological regulation#GO:0065007;positive regulation of lyase activity#GO:0051349;carboxylic acid metabolic process#GO:0019752;amino acid metabolic process#GO:0006520 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000006134.3|UniProtKB=F6V449 F6V449 PTHR24280:SF4 CYTOCHROME P450 20A1 CYTOCHROME P450 20A1 cellular anatomical entity#GO:0110165;membrane#GO:0016020 oxygenase#PC00177 CIOIN|Ensembl=ENSCING00000005474.3|UniProtKB=F7BDN3 F7BDN3 PTHR11616:SF321 SODIUM/CHLORIDE DEPENDENT TRANSPORTER SODIUM-DEPENDENT NUTRIENT AMINO ACID TRANSPORTER 1-RELATED inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;organic acid:sodium symporter activity#GO:0005343;organic acid transmembrane transporter activity#GO:0005342;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;organic anion transmembrane transporter activity#GO:0008514;monoatomic cation transmembrane transporter activity#GO:0008324;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;amino acid:sodium symporter activity#GO:0005283;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;metal ion transmembrane transporter activity#GO:0046873;active monoatomic ion transmembrane transporter activity#GO:0022853;amino acid transmembrane transporter activity#GO:0015171;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;organic anion transport#GO:0015711;amino acid transport#GO:0006865;organic acid transport#GO:0015849;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;amino acid import across plasma membrane#GO:0089718;carboxylic acid transmembrane transport#GO:1905039;localization#GO:0051179;organic substance transport#GO:0071702;import across plasma membrane#GO:0098739;amino acid transmembrane transport#GO:0003333;sodium ion transport#GO:0006814;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transport#GO:0006812;organic acid transmembrane transport#GO:1903825;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;import into cell#GO:0098657;sodium ion transmembrane transport#GO:0035725 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 primary active transporter#PC00068;transporter#PC00227 Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>CHT1#P01084 CIOIN|Ensembl=ENSCING00000007575.3|UniProtKB=F7AM88 F7AM88 PTHR15819:SF11 TRANSMEMBRANE PROTEIN FAM155 MID1, ISOFORM A calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;monoatomic ion channel activity#GO:0005216;inorganic cation transmembrane transporter activity#GO:0022890;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;calcium ion transmembrane transport#GO:0070588;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;calcium ion transport#GO:0006816;localization#GO:0051179;calcium ion import#GO:0070509;import across plasma membrane#GO:0098739;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;calcium ion transmembrane import into cytosol#GO:0097553;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;import into cell#GO:0098657 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 CIOIN|Ensembl=ENSCING00000000491.3|UniProtKB=F6YCI4 F6YCI4 LOC100175172 PTHR13360:SF1 ACTIVATING SIGNAL COINTEGRATOR 1 COMPLEX SUBUNIT 1 ACTIVATING SIGNAL COINTEGRATOR 1 COMPLEX SUBUNIT 1 regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000014543.2|UniProtKB=F7B7S8 F7B7S8 LOC100177506 PTHR18952:SF124 CARBONIC ANHYDRASE CARBONIC ANHYDRASE 7 carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829;hydro-lyase activity#GO:0016836;catalytic activity#GO:0003824 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 dehydratase#PC00091;lyase#PC00144 CIOIN|Ensembl=ENSCING00000006281.3|UniProtKB=F6V184 F6V184 LOC100186661 PTHR16002:SF4 TRANSMEMBRANE PROTEIN 248-LIKE TMEM248_TMEM219 DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000000539.3|UniProtKB=F6ULW5 F6ULW5 PTHR11690:SF296 AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED DEGENERIN-LIKE PROTEIN DEL-10 monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;ligand-gated monoatomic cation channel activity#GO:0099094;sodium channel activity#GO:0005272;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;ligand-gated channel activity#GO:0022834 localization#GO:0051179;sodium ion transport#GO:0006814;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;monoatomic cation transport#GO:0006812;inorganic ion transmembrane transport#GO:0098660;monoatomic ion transport#GO:0006811;cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;sodium ion transmembrane transport#GO:0035725 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 CIOIN|Ensembl=ENSCING00000007910.3|UniProtKB=F6ST44 F6ST44 LOC100179759 PTHR11390:SF20 PROKARYOTIC DNA TOPOISOMERASE DNA TOPOISOMERASE 3-BETA-1 catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on DNA#GO:0140097;isomerase activity#GO:0016853;catalytic activity#GO:0003824 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;DNA conformation change#GO:0071103;nucleic acid metabolic process#GO:0090304;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;response to stress#GO:0006950;organelle organization#GO:0006996;chromosome organization#GO:0051276;nitrogen compound metabolic process#GO:0006807;cellular response to stress#GO:0033554;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA metabolism protein#PC00009 CIOIN|Ensembl=ENSCING00000022466.1|UniProtKB=H2Y2Z9 H2Y2Z9 PTHR24412:SF497 KELCH PROTEIN KELCH-LIKE PROTEIN 18 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000002042.3|UniProtKB=F6YH93 F6YH93 PTHR22940:SF4 TIMEOUT/TIMELESS-2 PROTEIN TIMELESS HOMOLOG nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;signal transduction#GO:0007165;regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA metabolic process#GO:0051052;negative regulation of cell cycle process#GO:0010948;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;cell cycle checkpoint signaling#GO:0000075;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;DNA-templated DNA replication#GO:0006261;intracellular signal transduction#GO:0035556;negative regulation of DNA metabolic process#GO:0051053;negative regulation of cellular process#GO:0048523;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;negative regulation of cell cycle#GO:0045786;regulation of cell cycle phase transition#GO:1901987;negative regulation of cell cycle phase transition#GO:1901988;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;regulation of cell cycle process#GO:0010564;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;DNA integrity checkpoint signaling#GO:0031570;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;DNA replication checkpoint signaling#GO:0000076;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;cellular response to stress#GO:0033554;DNA replication#GO:0006260;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;DNA metabolic process#GO:0006259 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;nuclear replication fork#GO:0043596;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513;replication fork#GO:0005657 CIOIN|Ensembl=ENSCING00000019149.1|UniProtKB=H2XLH0 H2XLH0 PTHR10993:SF7 OCTANOYLTRANSFERASE LIPOYLTRANSFERASE 2, MITOCHONDRIAL-RELATED macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;protein modification process#GO:0036211;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;peptidyl-amino acid modification#GO:0018193;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 transferase#PC00220;metabolite interconversion enzyme#PC00262 Lipoate_biosynthesis#P02750>Lipoyl-protein ligase#P03003 CIOIN|Ensembl=ENSCING00000001369.3|UniProtKB=F6SWN3 F6SWN3 PTHR23334:SF69 CCAAT/ENHANCER BINDING PROTEIN CCAAT_ENHANCER-BINDING PROTEIN GAMMA sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 DNA-binding transcription factor#PC00218;basic leucine zipper transcription factor#PC00056 CIOIN|Ensembl=ENSCING00000000463.3|UniProtKB=Q2PEE5 Q2PEE5 Ci-IC5 PTHR21694:SF35 COILED-COIL DOMAIN-CONTAINING PROTEIN 63 OUTER DYNEIN ARM-DOCKING COMPLEX SUBUNIT 1 cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;outer dynein arm assembly#GO:0036158;cell projection organization#GO:0030030;microtubule cytoskeleton organization#GO:0000226;microtubule-based movement#GO:0007018;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;axoneme assembly#GO:0035082;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031;cilium movement#GO:0003341;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;microtubule bundle formation#GO:0001578;axonemal dynein complex assembly#GO:0070286;cytoskeleton organization#GO:0007010;plasma membrane bounded cell projection assembly#GO:0120031 axoneme#GO:0005930;cytoplasmic region#GO:0099568;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;plasma membrane bounded cell projection cytoplasm#GO:0032838;membrane-bounded organelle#GO:0043227;ciliary plasm#GO:0097014;cytoskeleton#GO:0005856;cell projection#GO:0042995;cilium#GO:0005929 CIOIN|Ensembl=ENSCING00000014378.2|UniProtKB=F7AG00 F7AG00 PTHR11814:SF257 SULFATE TRANSPORTER ANION TRANSPORTER SULP-7D inorganic molecular entity transmembrane transporter activity#GO:0015318;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;organic acid transmembrane transporter activity#GO:0005342;chloride transmembrane transporter activity#GO:0015108;monoatomic anion transmembrane transporter activity#GO:0008509;organic anion transmembrane transporter activity#GO:0008514;inorganic anion transmembrane transporter activity#GO:0015103;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 transporter#PC00227 CIOIN|Ensembl=ENSCING00000006182.3|UniProtKB=F7B1X4 F7B1X4 PTHR19918:SF8 CELL DIVISION CYCLE 20 CDC20 FIZZY -RELATED FI02843P protein-containing complex binding#GO:0044877;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;binding#GO:0005488 positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of protein metabolic process#GO:0051246;regulation of catabolic process#GO:0009894;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of proteasomal protein catabolic process#GO:1901800;protein catabolic process#GO:0030163;organonitrogen compound catabolic process#GO:1901565;regulation of protein catabolic process#GO:0042176;regulation of proteolysis involved in protein catabolic process#GO:1903050;positive regulation of proteolysis#GO:0045862;modification-dependent macromolecule catabolic process#GO:0043632;regulation of biological process#GO:0050789;positive regulation of metabolic process#GO:0009893;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;positive regulation of biological process#GO:0048518;proteolysis involved in protein catabolic process#GO:0051603;positive regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032436;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of proteolysis#GO:0030162;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;positive regulation of proteolysis involved in protein catabolic process#GO:1903052;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;organonitrogen compound metabolic process#GO:1901564;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of proteasomal protein catabolic process#GO:0061136;regulation of primary metabolic process#GO:0080090;positive regulation of protein metabolic process#GO:0051247;anaphase-promoting complex-dependent catabolic process#GO:0031145;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;positive regulation of catabolic process#GO:0009896;positive regulation of protein catabolic process#GO:0045732;regulation of metabolic process#GO:0019222;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434 ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;cullin-RING ubiquitin ligase complex#GO:0031461;transferase complex#GO:1990234;anaphase-promoting complex#GO:0005680;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;nuclear ubiquitin ligase complex#GO:0000152;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000018624.1|UniProtKB=H2XY59 H2XY59 PTHR43591:SF101 METHYLTRANSFERASE METHYLTRANSFERASE-LIKE PROTEIN 27 methyltransferase#PC00155;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000024683.1|UniProtKB=H2XWF6 H2XWF6 PTHR12400:SF51 INOSITOL POLYPHOSPHATE KINASE INOSITOL POLYPHOSPHATE MULTIKINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301 organic hydroxy compound metabolic process#GO:1901615;organophosphate biosynthetic process#GO:0090407;alcohol biosynthetic process#GO:0046165;cellular metabolic process#GO:0044237;alcohol metabolic process#GO:0006066;organic hydroxy compound biosynthetic process#GO:1901617;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;organophosphate metabolic process#GO:0019637;small molecule biosynthetic process#GO:0044283;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 kinase#PC00137 CIOIN|Ensembl=ENSCING00000015948.2|UniProtKB=F6X4N7 F6X4N7 PTHR45668:SF5 SERINE/THREONINE-PROTEIN PHOSPHATASE 5-RELATED SERINE_THREONINE-PROTEIN PHOSPHATASE 5 protein phosphatase#PC00195;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000007413.3|UniProtKB=F6RYM0 F6RYM0 LOC100176269 PTHR11461:SF211 SERINE PROTEASE INHIBITOR, SERPIN GH10112P-RELATED protease inhibitor#PC00191 CIOIN|Ensembl=ENSCING00000004441.3|UniProtKB=F6XEQ3 F6XEQ3 PTHR13793:SF160 PHD FINGER PROTEINS PHD FINGER PROTEIN RHINOCEROS regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 zinc finger transcription factor#PC00244 CIOIN|Ensembl=ENSCING00000020585.1|UniProtKB=H2XY62 H2XY62 PTHR45991:SF1 PACHYTENE CHECKPOINT PROTEIN 2 PACHYTENE CHECKPOINT PROTEIN 2 HOMOLOG cellular aromatic compound metabolic process#GO:0006725;negative regulation of biological process#GO:0048519;signal transduction#GO:0007165;nuclear division#GO:0000280;cell cycle process#GO:0022402;regulation of cellular component organization#GO:0051128;negative regulation of cell cycle process#GO:0010948;negative regulation of nuclear division#GO:0051784;nucleobase-containing compound metabolic process#GO:0006139;reciprocal homologous recombination#GO:0140527;regulation of biological process#GO:0050789;cell cycle checkpoint signaling#GO:0000075;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;meiotic cell cycle process#GO:1903046;negative regulation of organelle organization#GO:0010639;meiosis I cell cycle process#GO:0061982;reciprocal meiotic recombination#GO:0007131;reproductive process#GO:0022414;intracellular signal transduction#GO:0035556;negative regulation of cellular component organization#GO:0051129;negative regulation of cellular process#GO:0048523;signaling#GO:0023052;meiosis I#GO:0007127;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;regulation of nuclear division#GO:0051783;macromolecule metabolic process#GO:0043170;meiotic cell cycle#GO:0051321;negative regulation of cell cycle#GO:0045786;regulation of organelle organization#GO:0033043;regulation of cell cycle phase transition#GO:1901987;negative regulation of cell cycle phase transition#GO:1901988;cellular metabolic process#GO:0044237;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;regulation of cell cycle process#GO:0010564;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;reproduction#GO:0000003;regulation of meiotic cell cycle#GO:0051445;organelle organization#GO:0006996;meiotic nuclear division#GO:0140013;regulation of cellular process#GO:0050794;sexual reproduction#GO:0019953;biological regulation#GO:0065007;cell cycle#GO:0007049;organelle fission#GO:0048285;regulation of cell cycle#GO:0051726;homologous recombination#GO:0035825;DNA metabolic process#GO:0006259 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 CIOIN|Ensembl=ENSCING00000014099.2|UniProtKB=F6TDB0 F6TDB0 PTHR22803:SF155 MANNOSE, PHOSPHOLIPASE, LECTIN RECEPTOR RELATED ACCESSORY GLAND PROTEIN ACP29AB-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 membrane trafficking regulatory protein#PC00151 CIOIN|Ensembl=ENSCING00000020856.1|UniProtKB=Q3MQ22 Q3MQ22 atg5 PTHR13040:SF2 AUTOPHAGY PROTEIN 5 AUTOPHAGY PROTEIN 5 ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;acyltransferase activity#GO:0016746;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824 microautophagy#GO:0016237;cellular component biogenesis#GO:0044085;macroautophagy#GO:0016236;macromolecule modification#GO:0043412;protein modification process#GO:0036211;autophagy of mitochondrion#GO:0000422;response to extracellular stimulus#GO:0009991;biosynthetic process#GO:0009058;post-translational protein modification#GO:0043687;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;cellular component disassembly#GO:0022411;cellular response to starvation#GO:0009267;nitrogen compound metabolic process#GO:0006807;catabolic process#GO:0009056;mitochondrion organization#GO:0007005;protein metabolic process#GO:0019538;protein lipidation#GO:0006497;cellular response to extracellular stimulus#GO:0031668;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular component assembly#GO:0022607;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cell communication#GO:0007154;cellular component organization#GO:0016043;response to nutrient levels#GO:0031667;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organelle disassembly#GO:1903008;lipoprotein biosynthetic process#GO:0042158;primary metabolic process#GO:0044238;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;response to stress#GO:0006950;organelle organization#GO:0006996;cellular response to nutrient levels#GO:0031669;response to starvation#GO:0042594;cellular response to external stimulus#GO:0071496;autophagosome assembly#GO:0000045;lipoprotein metabolic process#GO:0042157;cellular response to stress#GO:0033554;piecemeal microautophagy of the nucleus#GO:0034727;autophagy#GO:0006914 intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;organelle#GO:0043226;organelle membrane contact site#GO:0044232;membrane#GO:0016020;intracellular organelle#GO:0043229;autophagosome#GO:0005776;mitochondria-associated endoplasmic reticulum membrane#GO:0044233;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;phagophore assembly site#GO:0000407;membrane-bounded organelle#GO:0043227 membrane trafficking regulatory protein#PC00151 CIOIN|Ensembl=ENSCING00000019130.1|UniProtKB=H2XKI3 H2XKI3 PTHR23121:SF9 SODIUM-DEPENDENT GLUCOSE TRANSPORTER 1 SODIUM-DEPENDENT GLUCOSE TRANSPORTER 1 transmembrane transporter activity#GO:0022857;sugar transmembrane transporter activity#GO:0051119;transporter activity#GO:0005215;carbohydrate transmembrane transporter activity#GO:0015144 transporter#PC00227 CIOIN|Ensembl=ENSCING00000016721.2|UniProtKB=F7AYD9 F7AYD9 LOC100177321 PTHR23264:SF19 NUCLEOTIDE-BINDING PROTEIN NBP35 YEAST -RELATED CYTOSOLIC FE-S CLUSTER ASSEMBLY FACTOR NUBP2 small molecule binding#GO:0036094;binding#GO:0005488;iron-sulfur cluster binding#GO:0051536 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;iron-sulfur cluster assembly#GO:0016226;cellular component organization#GO:0016043;cellular process#GO:0009987 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000012507.2|UniProtKB=F7BEA7 F7BEA7 PTHR24104:SF48 E3 UBIQUITIN-PROTEIN LIGASE NHLRC1-RELATED PROTEIN WECH transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein polyubiquitination#GO:0000209;proteasomal protein catabolic process#GO:0010498;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000000899.3|UniProtKB=F6U1G9 F6U1G9 LOC100181983 PTHR15093:SF1 PROSTATE APOPTOSIS RESPONSE PROTEIN PAR-4 PRKC APOPTOSIS WT1 REGULATOR PROTEIN CIOIN|Ensembl=ENSCING00000006005.3|UniProtKB=F6T302 F6T302 PTHR10270:SF324 SOX TRANSCRIPTION FACTOR SOX DOMAIN-CONTAINING PROTEIN DICHAETE-RELATED DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;cell differentiation#GO:0030154;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA metabolic process#GO:0051252;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;positive regulation of RNA metabolic process#GO:0051254;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;HMG box transcription factor#PC00024 CIOIN|Ensembl=ENSCING00000005347.4|UniProtKB=F7BEF3 F7BEF3 LOC100181431 PTHR11353:SF23 CHAPERONIN T-COMPLEX PROTEIN 1 SUBUNIT BETA protein binding#GO:0005515;unfolded protein binding#GO:0051082;binding#GO:0005488 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein folding#GO:0006457;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;chaperonin-containing T-complex#GO:0005832;protein folding chaperone complex#GO:0101031;intracellular anatomical structure#GO:0005622 chaperonin#PC00073 CIOIN|Ensembl=ENSCING00000019127.1|UniProtKB=H2XL83 H2XL83 LOC100178413 PTHR12581:SF0 HIV-1 REV BINDING PROTEIN 2, 3 KRR1 SMALL SUBUNIT PROCESSOME COMPONENT HOMOLOG membrane-enclosed lumen#GO:0031974;small-subunit processome#GO:0032040;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;nuclear lumen#GO:0031981 RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000021397.1|UniProtKB=H2Y346 H2Y346 PTHR12461:SF27 HYPOXIA-INDUCIBLE FACTOR 1 ALPHA INHIBITOR-RELATED JMJC DOMAIN-CONTAINING PROTEIN protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000024104.1|UniProtKB=H2XVE9 H2XVE9 PTHR12461:SF104 HYPOXIA-INDUCIBLE FACTOR 1 ALPHA INHIBITOR-RELATED TRNA WYBUTOSINE-SYNTHESIZING PROTEIN 5 tRNA binding#GO:0000049;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;carbohydrate derivative metabolic process#GO:1901135;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;RNA modification#GO:0009451;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;tRNA modification#GO:0006400;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;cellular metabolic process#GO:0044237;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nucleic acid metabolic process#GO:0090304;glycosyl compound metabolic process#GO:1901657 protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000013208.2|UniProtKB=F6VSM6 F6VSM6 PTHR43975:SF2 ZGC:101858 EG:BACR7A4.14 PROTEIN-RELATED CIOIN|Ensembl=ENSCING00000002277.4|UniProtKB=F6VGC6 F6VGC6 PTHR10997:SF8 IMPORTIN-7, 8, 11 EXPORTIN-2 cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;protein localization to nucleus#GO:0034504;nitrogen compound transport#GO:0071705;establishment of protein localization to organelle#GO:0072594;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;protein import into nucleus#GO:0006606;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;nuclear export#GO:0051168;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;protein export from nucleus#GO:0006611;intracellular transport#GO:0046907;protein localization to organelle#GO:0033365;nuclear transport#GO:0051169;import into nucleus#GO:0051170 envelope#GO:0031975;cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear envelope#GO:0005635;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transporter#PC00227 CIOIN|Ensembl=ENSCING00000000787.3|UniProtKB=F6VSD5 F6VSD5 PTHR46337:SF1 RCC1-LIKE G EXCHANGING FACTOR-LIKE PROTEIN RCC1-LIKE G EXCHANGING FACTOR-LIKE PROTEIN CIOIN|Ensembl=ENSCING00000014291.2|UniProtKB=F6VDW8 F6VDW8 PTHR11011:SF45 MALE STERILITY PROTEIN 2-RELATED FATTY ACYL-COA REDUCTASE CG8306-RELATED oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;lipid metabolic process#GO:0006629;heterocycle metabolic process#GO:0046483;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;acyl-CoA metabolic process#GO:0006637;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;amide metabolic process#GO:0043603;purine nucleotide metabolic process#GO:0006163;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;nucleobase-containing small molecule metabolic process#GO:0055086 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000004779.3|UniProtKB=L7N0S0 L7N0S0 LOC100183637 PTHR24300:SF397 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 2U1 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;tetrapyrrole binding#GO:0046906;steroid hydroxylase activity#GO:0008395;oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497;heme binding#GO:0020037 response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;response to chemical#GO:0042221;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 oxygenase#PC00177;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000013978.2|UniProtKB=F6RIZ5 F6RIZ5 LOC100186957 PTHR11106:SF27 GANGLIOSIDE INDUCED DIFFERENTIATION ASSOCIATED PROTEIN 2-RELATED MACRO DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000004990.3|UniProtKB=F6WLW9 F6WLW9 PTHR14920:SF0 OSMOTIC AVOIDANCE ABNORMAL PROTEIN 1/WD REPEAT MEMBRANE PROTEIN WD REPEAT DOMAIN 19 cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;cilium assembly#GO:0060271;cell projection organization#GO:0030030;transport#GO:0006810;microtubule-based movement#GO:0007018;cellular component organization#GO:0016043;intraciliary retrograde transport#GO:0035721;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;transport along microtubule#GO:0010970;cell projection assembly#GO:0030031;intraciliary transport#GO:0042073;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based transport#GO:0099111;microtubule-based process#GO:0007017;establishment of localization#GO:0051234;organelle organization#GO:0006996;cytoskeleton-dependent intracellular transport#GO:0030705;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;protein-containing complex localization#GO:0031503 protein-containing complex#GO:0032991;intraciliary transport particle A#GO:0030991;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cilium#GO:0005929;intraciliary transport particle#GO:0030990 CIOIN|Ensembl=ENSCING00000025228.1|UniProtKB=Q8HIM8 Q8HIM8 NADH5 PTHR42829:SF2 NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 5 NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 5 NADH dehydrogenase activity#GO:0003954;oxidoreductase activity, acting on NAD(P)H#GO:0016651;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;proton transmembrane transport#GO:1902600;monoatomic ion transmembrane transport#GO:0034220;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;monoatomic cation transport#GO:0006812;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000004062.3|UniProtKB=F6Z145 F6Z145 PTHR48027:SF18 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN 87F-RELATED HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN 87F-RELATED CIOIN|Ensembl=ENSCING00000002726.3|UniProtKB=F6TQ36 F6TQ36 PTHR24255:SF38 COMPLEMENT COMPONENT 1, S SUBCOMPONENT-RELATED MANNAN-BINDING LECTIN SERINE PROTEASE 1-LIKE hydrolase activity#GO:0016787;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 serine protease#PC00203;protease#PC00190 CIOIN|Ensembl=ENSCING00000001729.3|UniProtKB=F6TVB5 F6TVB5 PTHR31817:SF0 FAMILY NOT NAMED CHROMOSOME UNDETERMINED SCAFFOLD_67, WHOLE GENOME SHOTGUN SEQUENCE CIOIN|Ensembl=ENSCING00000006863.3|UniProtKB=F6ZD62 F6ZD62 PTHR24404:SF113 ZINC FINGER PROTEIN C2H2-TYPE DOMAIN-CONTAINING PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 CIOIN|Ensembl=ENSCING00000021562.1|UniProtKB=H2Y1A0 H2Y1A0 PTHR15189:SF7 BRISC AND BRCA1-A COMPLEX MEMBER 2 BRISC AND BRCA1-A COMPLEX MEMBER 2 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;DNA damage response#GO:0006974;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;BRCA1-A complex#GO:0070531;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000001683.3|UniProtKB=F6X863 F6X863 PTHR11592:SF81 GLUTATHIONE PEROXIDASE GLUTATHIONE PEROXIDASE oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;antioxidant activity#GO:0016209;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 peroxidase#PC00180;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000023761.1|UniProtKB=Q1RLE7 Q1RLE7 Ci-ZF(C2H2)-84 PTHR13723:SF303 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE SUBFAMILY NOT NAMED hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular component organization or biogenesis#GO:0071840;extracellular structure organization#GO:0043062;external encapsulating structure organization#GO:0045229;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;cellular component organization#GO:0016043;cellular process#GO:0009987;protein metabolic process#GO:0019538;extracellular matrix organization#GO:0030198;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944 metalloprotease#PC00153;protease#PC00190 CIOIN|Ensembl=ENSCING00000001328.3|UniProtKB=F6W9C9 F6W9C9 capza PTHR10653:SF0 F-ACTIN-CAPPING PROTEIN SUBUNIT ALPHA F-ACTIN-CAPPING PROTEIN SUBUNIT ALPHA cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 negative regulation of protein polymerization#GO:0032272;negative regulation of protein depolymerization#GO:1901880;negative regulation of biological process#GO:0048519;negative regulation of actin filament depolymerization#GO:0030835;regulation of cellular component organization#GO:0051128;regulation of actin polymerization or depolymerization#GO:0008064;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;actin filament-based process#GO:0030029;regulation of protein-containing complex assembly#GO:0043254;regulation of biological quality#GO:0065008;regulation of cellular component biogenesis#GO:0044087;negative regulation of organelle organization#GO:0010639;negative regulation of protein-containing complex disassembly#GO:0043242;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;barbed-end actin filament capping#GO:0051016;regulation of actin filament-based process#GO:0032970;negative regulation of cellular component organization#GO:0051129;regulation of protein polymerization#GO:0032271;negative regulation of cellular process#GO:0048523;regulation of anatomical structure size#GO:0090066;regulation of actin filament length#GO:0030832;regulation of organelle organization#GO:0033043;regulation of actin filament organization#GO:0110053;regulation of protein-containing complex disassembly#GO:0043244;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of actin filament polymerization#GO:0030833;regulation of cellular component size#GO:0032535;negative regulation of supramolecular fiber organization#GO:1902904;regulation of supramolecular fiber organization#GO:1902903;cellular component organization or biogenesis#GO:0071840;regulation of protein depolymerization#GO:1901879;regulation of actin filament depolymerization#GO:0030834;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;negative regulation of actin filament polymerization#GO:0030837;biological regulation#GO:0065007;negative regulation of protein-containing complex assembly#GO:0031333;actin cytoskeleton organization#GO:0030036;negative regulation of cytoskeleton organization#GO:0051494 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;cortical cytoskeleton#GO:0030863;cell cortex#GO:0005938;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-motor actin binding protein#PC00165 CIOIN|Ensembl=ENSCING00000021809.1|UniProtKB=H2Y1N8 H2Y1N8 PTHR32261:SF1 CALCIUM HOMEOSTASIS MODULATOR PROTEIN CALCIUM HOMEOSTASIS MODULATOR PROTEIN monoatomic cation channel activity#GO:0005261;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;transporter activity#GO:0005215 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 transporter#PC00227;voltage-gated ion channel#PC00241 CIOIN|Ensembl=ENSCING00000014461.2|UniProtKB=F6R5E2 F6R5E2 PTHR23011:SF28 CYCLIC NUCLEOTIDE-BINDING DOMAIN CONTAINING PROTEIN CYCLIC NUCLEOTIDE-BINDING DOMAIN CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000011747.2|UniProtKB=H2XRR3 H2XRR3 PTHR10728:SF40 CYTOSOLIC PHOSPHOLIPASE A2 PATATIN FAMILY PROTEIN hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;phospholipase A2 activity#GO:0004623;phospholipase activity#GO:0004620;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;cellular metabolic process#GO:0044237;glycerophospholipid metabolic process#GO:0006650;glycerolipid catabolic process#GO:0046503;lipid catabolic process#GO:0016042;glycerophospholipid catabolic process#GO:0046475;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate catabolic process#GO:0046434;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;phospholipid catabolic process#GO:0009395;catabolic process#GO:0009056;organophosphate metabolic process#GO:0019637;organic substance catabolic process#GO:1901575;cellular lipid metabolic process#GO:0044255;cellular lipid catabolic process#GO:0044242;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 phospholipase#PC00186 CIOIN|Ensembl=ENSCING00000001552.3|UniProtKB=F6YJM6 F6YJM6 LOC100177912 PTHR11785:SF512 AMINO ACID TRANSPORTER SOBREMESA, ISOFORM B L-amino acid transmembrane transporter activity#GO:0015179;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;amino acid transmembrane transporter activity#GO:0015171;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215;organic acid transmembrane transporter activity#GO:0005342 localization#GO:0051179;organic substance transport#GO:0071702;amino acid transmembrane transport#GO:0003333;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;amino acid transport#GO:0006865;organic anion transport#GO:0015711;organic acid transport#GO:0015849;transport#GO:0006810;nitrogen compound transport#GO:0071705;organic acid transmembrane transport#GO:1903825;carboxylic acid transport#GO:0046942;cellular process#GO:0009987;carboxylic acid transmembrane transport#GO:1905039 transporter#PC00227 CIOIN|Ensembl=ENSCING00000011284.2|UniProtKB=F6Y965 F6Y965 LOC100175885 PTHR12243:SF69 MADF DOMAIN TRANSCRIPTION FACTOR SI:CH73-59F11.3 regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218 CIOIN|Ensembl=ENSCING00000006945.3|UniProtKB=F6VND6 F6VND6 rar PTHR24082:SF464 NUCLEAR HORMONE RECEPTOR RETINOIC ACID RECEPTOR cis-regulatory region sequence-specific DNA binding#GO:0000987;signaling receptor activity#GO:0038023;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular transducer activity#GO:0060089;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;hormone-mediated signaling pathway#GO:0009755;regulation of biological process#GO:0050789;cellular response to hormone stimulus#GO:0032870;negative regulation of DNA-templated transcription#GO:0045892;positive regulation of biological process#GO:0048518;cellular developmental process#GO:0048869;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;negative regulation of metabolic process#GO:0009892;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of nitrogen compound metabolic process#GO:0051172;positive regulation of cellular process#GO:0048522;regulation of cellular process#GO:0050794;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;negative regulation of cellular metabolic process#GO:0031324;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;positive regulation of RNA biosynthetic process#GO:1902680;negative regulation of RNA biosynthetic process#GO:1902679;developmental process#GO:0032502;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of biosynthetic process#GO:0009891;cell differentiation#GO:0030154;response to endogenous stimulus#GO:0009719;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;intracellular receptor signaling pathway#GO:0030522;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;negative regulation of biosynthetic process#GO:0009890;regulation of DNA-templated transcription#GO:0006355;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;response to stimulus#GO:0050896;regulation of cellular biosynthetic process#GO:0031326;response to hormone#GO:0009725;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;positive regulation of RNA metabolic process#GO:0051254 C4 zinc finger nuclear receptor#PC00169;zinc finger transcription factor#PC00244 CIOIN|Ensembl=ENSCING00000014131.2|UniProtKB=F6SQS1 F6SQS1 PTHR46167:SF1 N-LYSINE METHYLTRANSFERASE KMT5A N-LYSINE METHYLTRANSFERASE KMT5A N-methyltransferase activity#GO:0008170;histone modifying activity#GO:0140993;transferase activity#GO:0016740;catalytic activity#GO:0003824;histone methyltransferase activity#GO:0042054;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;protein-lysine N-methyltransferase activity#GO:0016279;catalytic activity, acting on a protein#GO:0140096;lysine N-methyltransferase activity#GO:0016278;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;protein methyltransferase activity#GO:0008276 regulation of cell communication#GO:0010646;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of signaling#GO:0023051;regulation of response to stress#GO:0080134;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of intracellular signal transduction#GO:1902531;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of cellular response to stress#GO:0080135;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000014596.2|UniProtKB=F6SYC7 F6SYC7 LOC100179025 PTHR22802:SF379 C-TYPE LECTIN SUPERFAMILY MEMBER CHONDROITIN SULFATE PROTEOGLYCAN 2 ISOFORM X1 membrane traffic protein#PC00150 CIOIN|Ensembl=ENSCING00000002345.1|UniProtKB=Q7YT74 Q7YT74 LOC448958 PTHR24072:SF169 RHO FAMILY GTPASE RAS-RELATED C3 BOTULINUM TOXIN SUBSTRATE 2 GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;enzyme binding#GO:0019899;ribonucleoside triphosphate phosphatase activity#GO:0017111;kinase binding#GO:0019900;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;protein kinase binding#GO:0019901;anion binding#GO:0043168;ion binding#GO:0043167 establishment or maintenance of cell polarity#GO:0007163;regulation of anatomical structure morphogenesis#GO:0022603;regulation of organelle organization#GO:0033043;regulation of cellular component organization#GO:0051128;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of cytoskeleton organization#GO:0051493;regulation of cell shape#GO:0008360;regulation of biological quality#GO:0065008;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;cortical cytoskeleton organization#GO:0030865;biological regulation#GO:0065007;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;regulation of actin filament-based process#GO:0032970 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 small GTPase#PC00208 T cell activation#P00053>rac#P01324;Huntington disease#P00029>Rac#P00775;p38 MAPK pathway#P05918>Rac#P06021;Cytoskeletal regulation by Rho GTPase#P00016>Rac#P00523;EGF receptor signaling pathway#P00018>Rac#P00564;Axon guidance mediated by semaphorins#P00007>Rac#P00340;VEGF signaling pathway#P00056>Rac#P01421;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Cdc42#P00834;Ras Pathway#P04393>Rac#P04559;Axon guidance mediated by netrin#P00009>Rac#P00366;B cell activation#P00010>Rac#P00385;Integrin signalling pathway#P00034>Rac#P00927;Axon guidance mediated by Slit/Robo#P00008>Rac#P00354;FGF signaling pathway#P00021>Rac#P00645 CIOIN|Ensembl=ENSCING00000005118.3|UniProtKB=F6VYS2 F6VYS2 zf(bbox_ring_phd)-1 PTHR45915:SF6 TRANSCRIPTION INTERMEDIARY FACTOR E3 UBIQUITIN-PROTEIN LIGASE TRIM33 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;protein-DNA complex#GO:0032993;chromosome#GO:0005694;chromatin#GO:0000785;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 CIOIN|Ensembl=ENSCING00000005570.3|UniProtKB=F6URQ1 F6URQ1 LOC100180117 PTHR21084:SF1 DENSE INCISORS DENSE INCISORS CIOIN|Ensembl=ENSCING00000003482.3|UniProtKB=F6TM76 F6TM76 PTHR19143:SF458 FIBRINOGEN/TENASCIN/ANGIOPOEITIN FIBRINOGEN C-TERMINAL DOMAIN-CONTAINING PROTEIN-RELATED external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 CIOIN|Ensembl=ENSCING00000006433.3|UniProtKB=F6QLP3 F6QLP3 LOC100184863 PTHR14002:SF20 ENDOGLIN/TGF-BETA RECEPTOR TYPE III ZONA PELLUCIDA-LIKE DOMAIN-CONTAINING PROTEIN 1 transmembrane signal receptor#PC00197 CIOIN|Ensembl=ENSCING00000023819.1|UniProtKB=H2XVH5 H2XVH5 PTHR44942:SF4 METHYLTRANSF_11 DOMAIN-CONTAINING PROTEIN METHYLTRANSFERASE TYPE 11 DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000009220.3|UniProtKB=F6WMV3 F6WMV3 PTHR16206:SF4 DEP DOMAIN-CONTAINING PROTEIN LET-99 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000008779.3|UniProtKB=F6SZN1 F6SZN1 PTHR47385:SF18 CALPONIN CALPONIN cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000005596.3|UniProtKB=F6U3A5 F6U3A5 MED8 PTHR13074:SF9 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 8 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 8 general transcription factor#PC00259 CIOIN|Ensembl=ENSCING00000024050.1|UniProtKB=H2XQ18 H2XQ18 PTHR22878:SF69 DYNEIN HEAVY CHAIN 6, AXONEMAL-LIKE-RELATED DYNEIN HEAVY CHAIN CIOIN|Ensembl=ENSCING00000005462.3|UniProtKB=F6U609 F6U609 PTHR10894:SF1 NUCLEOLAR PROTEIN 5 NUCLEOLAR PROTEIN NOP5 NOP58 NUCLEOLAR PROTEIN 58 snoRNA binding#GO:0030515;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 small-subunit processome#GO:0032040;ribonucleoprotein complex#GO:1990904;preribosome#GO:0030684;protein-containing complex#GO:0032991;sno(s)RNA-containing ribonucleoprotein complex#GO:0005732 RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000006082.3|UniProtKB=F6ZFZ3 F6ZFZ3 PTHR23235:SF164 KRUEPPEL-LIKE TRANSCRIPTION FACTOR C2H2-TYPE DOMAIN-CONTAINING PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 CIOIN|Ensembl=ENSCING00000023307.1|UniProtKB=H2XWF9 H2XWF9 PTHR14494:SF0 ALADIN/ADRACALIN/AAAS ALADIN localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;transport#GO:0006810;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;cellular process#GO:0009987;nuclear transport#GO:0051169 envelope#GO:0031975;nuclear pore#GO:0005643;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear envelope#GO:0005635;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000024853.1|UniProtKB=F7A5Z0 F7A5Z0 PTHR24314:SF20 NON-SPECIFIC LIPID TRANSFER PROTEIN-RELATED STEROL CARRIER PROTEIN 2 transfer/carrier protein#PC00219 CIOIN|Ensembl=ENSCING00000003297.3|UniProtKB=F6W239 F6W239 LOC100178206 PTHR10083:SF328 KUNITZ-TYPE PROTEASE INHIBITOR-RELATED TISSUE FACTOR PATHWAY INHIBITOR peptidase inhibitor activity#GO:0030414;molecular function regulator activity#GO:0098772;serine-type endopeptidase inhibitor activity#GO:0004867;peptidase regulator activity#GO:0061134;enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;endopeptidase regulator activity#GO:0061135;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191;protein-binding activity modulator#PC00095 Blood coagulation#P00011>TFPI#P00417 CIOIN|Ensembl=ENSCING00000023681.1|UniProtKB=H2XK62 H2XK62 PTHR21451:SF0 HISTONE H3 METHYLTRANSFERASE HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC N-methyltransferase activity#GO:0008170;histone modifying activity#GO:0140993;transferase activity#GO:0016740;catalytic activity#GO:0003824;histone methyltransferase activity#GO:0042054;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;protein-lysine N-methyltransferase activity#GO:0016279;catalytic activity, acting on a protein#GO:0140096;lysine N-methyltransferase activity#GO:0016278;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;protein methyltransferase activity#GO:0008276 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;DNA damage checkpoint signaling#GO:0000077;negative regulation of cell cycle process#GO:0010948;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;cell cycle checkpoint signaling#GO:0000075;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;regulation of molecular function#GO:0065009;nitrogen compound metabolic process#GO:0006807;signal transduction in response to DNA damage#GO:0042770;intracellular signal transduction#GO:0035556;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;negative regulation of cell cycle#GO:0045786;macromolecule metabolic process#GO:0043170;negative regulation of cell cycle phase transition#GO:1901988;regulation of cell cycle phase transition#GO:1901987;cellular metabolic process#GO:0044237;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;regulation of cell cycle process#GO:0010564;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;DNA integrity checkpoint signaling#GO:0031570;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077;histone modifying enzyme#PC00261 CIOIN|Ensembl=ENSCING00000004828.3|UniProtKB=F6R8Z1 F6R8Z1 LOC100178064 PTHR13136:SF16 TESTIS DEVELOPMENT PROTEIN PRTD KAT8 REGULATORY NSL COMPLEX SUBUNIT 3 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of RNA metabolic process#GO:0051254;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 histone acetyltransferase complex#GO:0000123;acetyltransferase complex#GO:1902493;chromatin#GO:0000785;protein-DNA complex#GO:0032993;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein acetyltransferase complex#GO:0031248;protein-containing complex#GO:0032991;chromosome#GO:0005694 CIOIN|Ensembl=ENSCING00000006958.3|UniProtKB=F6SZ54 F6SZ54 LOC100176938 PTHR22847:SF637 WD40 REPEAT PROTEIN WD REPEAT DOMAIN 5B CIOIN|Ensembl=ENSCING00000005658.3|UniProtKB=F6Y1U4 F6Y1U4 PTHR23505:SF96 SPINSTER LP14756P cellular anatomical entity#GO:0110165;membrane#GO:0016020 transporter#PC00227 CIOIN|Ensembl=ENSCING00000000221.3|UniProtKB=F6V5N5 F6V5N5 LOC100182241 PTHR15907:SF161 DUF614 FAMILY PROTEIN-RELATED PLAC8 FAMILY PROTEIN CIOIN|Ensembl=ENSCING00000019949.1|UniProtKB=H2Y1M3 H2Y1M3 PTHR45710:SF26 C-TYPE LECTIN DOMAIN-CONTAINING PROTEIN 180 RH26557P defense/immunity protein#PC00090 CIOIN|Ensembl=ENSCING00000001531.3|UniProtKB=H2XQ88 H2XQ88 PTHR19143:SF459 FIBRINOGEN/TENASCIN/ANGIOPOEITIN FIBRINOGEN C-TERMINAL DOMAIN-CONTAINING PROTEIN external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 CIOIN|Ensembl=ENSCING00000020849.1|UniProtKB=H2XVK2 H2XVK2 PTHR13693:SF3 CLASS II AMINOTRANSFERASE/8-AMINO-7-OXONONANOATE SYNTHASE LD36009P transaminase#PC00216;transferase#PC00220;metabolite interconversion enzyme#PC00262 Biotin biosynthesis#P02731>8-Amino-7-oxononanoate synthase#P02858 CIOIN|Ensembl=ENSCING00000007834.3|UniProtKB=F6WTM4 F6WTM4 LOC100181614 PTHR44156:SF6 SUPERNUMERARY LIMBS, ISOFORM B-RELATED DYNEIN ASSEMBLY FACTOR WITH WDR REPEAT DOMAINS 1 CIOIN|Ensembl=ENSCING00000007984.3|UniProtKB=F6WQV1 F6WQV1 PTHR24115:SF418 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF12 pyrophosphatase activity#GO:0016462;cytoskeletal protein binding#GO:0008092;microtubule motor activity#GO:0003777;tubulin binding#GO:0015631;ATP-dependent activity#GO:0140657;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;cytoskeletal motor activity#GO:0003774;microtubule binding#GO:0008017;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;ribonucleoside triphosphate phosphatase activity#GO:0017111;ATP hydrolysis activity#GO:0016887 microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;microtubule associated complex#GO:0005875;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 CIOIN|Ensembl=ENSCING00000022292.1|UniProtKB=H2Y3J7 H2Y3J7 LOC100185223 PTHR24256:SF545 TRYPTASE-RELATED INACTIVE SERINE PROTEASE 54 hydrolase activity#GO:0016787;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 serine protease#PC00203;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000009108.3|UniProtKB=F6Q950 F6Q950 LOC100184264 PTHR20905:SF1 N-ACETYLTRANSFERASE-RELATED AT07410P-RELATED acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;N-acetyltransferase activity#GO:0008080;acyltransferase activity#GO:0016746;acetyltransferase activity#GO:0016407;catalytic activity#GO:0003824;N-acyltransferase activity#GO:0016410 acetyltransferase#PC00038 CIOIN|Ensembl=ENSCING00000003142.3|UniProtKB=F6QE16 F6QE16 PTHR45780:SF2 ETHANOLAMINE-PHOSPHATE CYTIDYLYLTRANSFERASE ETHANOLAMINE-PHOSPHATE CYTIDYLYLTRANSFERASE transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779 lipid metabolic process#GO:0006629;phospholipid biosynthetic process#GO:0008654;organophosphate biosynthetic process#GO:0090407;glycerolipid biosynthetic process#GO:0045017;cellular metabolic process#GO:0044237;glycerophospholipid metabolic process#GO:0006650;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;phospholipid metabolic process#GO:0006644;lipid biosynthetic process#GO:0008610;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;primary metabolic process#GO:0044238;glycerolipid metabolic process#GO:0046486;glycerophospholipid biosynthetic process#GO:0046474;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 nucleotidyltransferase#PC00174 CIOIN|Ensembl=ENSCING00000006238.3|UniProtKB=C4B8X5 C4B8X5 Ci-MORN40 PTHR43215:SF14 RADIAL SPOKE HEAD 1 HOMOLOG RADIAL SPOKE HEAD 1 HOMOLOG CIOIN|Ensembl=ENSCING00000003562.3|UniProtKB=A0A1W3JUY2 A0A1W3JUY2 LOC100176701 PTHR11157:SF126 FATTY ACID ACYL TRANSFERASE-RELATED ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824 organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;monocarboxylic acid biosynthetic process#GO:0072330;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;organic acid metabolic process#GO:0006082;membrane lipid biosynthetic process#GO:0046467;sphingolipid metabolic process#GO:0006665;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;fatty acid metabolic process#GO:0006631;membrane lipid metabolic process#GO:0006643;nitrogen compound metabolic process#GO:0006807;small molecule biosynthetic process#GO:0044283;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;sphingolipid biosynthetic process#GO:0030148;fatty acid biosynthetic process#GO:0006633;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 acyltransferase#PC00042 CIOIN|Ensembl=ENSCING00000018923.1|UniProtKB=H2XQT8 H2XQT8 LOC101242525 PTHR31331:SF1 LCCL DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_5G08630) CYSTEINE RICH SECRETORY PROTEIN LCCL DOMAIN CONTAINING 2 CIOIN|Ensembl=ENSCING00000008175.3|UniProtKB=F6PP55 F6PP55 PTHR19134:SF527 RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 7 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;protein tyrosine phosphatase activity#GO:0004725;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 protein phosphatase#PC00195;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000011615.2|UniProtKB=F6QK87 F6QK87 PTHR19297:SF181 GLYCOSYLTRANSFERASE 14 FAMILY MEMBER PROTEIN XYLOSYLTRANSFERASE acetylglucosaminyltransferase activity#GO:0008375;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194;hexosyltransferase activity#GO:0016758 glycosyltransferase#PC00111;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000012001.2|UniProtKB=F6RWY1 F6RWY1 LOC100181439 PTHR21635:SF0 LEUCINE ZIPPER TRANSCRIPTION FACTOR LIKE LEUCINE ZIPPER TRANSCRIPTION FACTOR-LIKE PROTEIN 1 regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of localization#GO:0032879;regulation of cellular localization#GO:0060341;negative regulation of cellular process#GO:0048523;regulation of protein localization#GO:0032880 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;basic leucine zipper transcription factor#PC00056 CIOIN|Ensembl=ENSCING00000008048.3|UniProtKB=F6S4W3 F6S4W3 PTHR46830:SF1 TRANSFERASE, PUTATIVE-RELATED ALPHA-1,4-N-ACETYLGLUCOSAMINYLTRANSFERASE transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000001876.3|UniProtKB=F6SJY4 F6SJY4 LOC100175784 PTHR13398:SF0 GDP-FUCOSE PROTEIN O-FUCOSYLTRANSFERASE 2 GDP-FUCOSE PROTEIN O-FUCOSYLTRANSFERASE 2 transferase activity#GO:0016740;fucosyltransferase activity#GO:0008417;catalytic activity, acting on a protein#GO:0140096;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000024507.1|UniProtKB=H2Y3E3 H2Y3E3 PTHR13723:SF305 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE PROTEIN MADD-4 hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular component organization or biogenesis#GO:0071840;extracellular structure organization#GO:0043062;external encapsulating structure organization#GO:0045229;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;cellular component organization#GO:0016043;cellular process#GO:0009987;protein metabolic process#GO:0019538;extracellular matrix organization#GO:0030198;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944 metalloprotease#PC00153;protease#PC00190 CIOIN|Ensembl=ENSCING00000005231.3|UniProtKB=F6YHR6 F6YHR6 LOC104265388 PTHR11216:SF1 EH DOMAIN SARCALUMENIN localization#GO:0051179;endosomal transport#GO:0016197;cellular localization#GO:0051641;establishment of localization#GO:0051234;transport#GO:0006810;endocytosis#GO:0006897;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;cellular process#GO:0009987;import into cell#GO:0098657 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 membrane traffic protein#PC00150 CIOIN|Ensembl=ENSCING00000013365.2|UniProtKB=F6YE85 F6YE85 LOC100175394 PTHR35539:SF1 CDNA SEQUENCE BC048562 CDNA SEQUENCE BC048562 CIOIN|Ensembl=ENSCING00000019901.1|UniProtKB=H2XQ93 H2XQ93 PTHR24034:SF200 EGF-LIKE DOMAIN-CONTAINING PROTEIN EGF-LIKE AND EMI DOMAIN-CONTAINING PROTEIN 1 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 CIOIN|Ensembl=ENSCING00000005931.3|UniProtKB=F6ZGZ0 F6ZGZ0 PTHR11164:SF0 GLUTAMATE CYSTEINE LIGASE GLUTAMATE--CYSTEINE LIGASE CATALYTIC SUBUNIT ligase activity#GO:0016874;catalytic activity#GO:0003824 sulfur compound metabolic process#GO:0006790;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;glutathione metabolic process#GO:0006749;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;cellular modified amino acid metabolic process#GO:0006575;amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 ligase#PC00142;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000005442.3|UniProtKB=F6UUL4 F6UUL4 LOC100178216 PTHR10743:SF0 PROTEIN RER1 PROTEIN RER1 localization#GO:0051179;cellular localization#GO:0051641;protein localization to endoplasmic reticulum#GO:0070972;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;maintenance of location#GO:0051235;maintenance of location in cell#GO:0051651;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;transport#GO:0006810;vesicle-mediated transport#GO:0016192;protein localization to organelle#GO:0033365;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;protein localization#GO:0008104 cytoplasm#GO:0005737;bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;Golgi membrane#GO:0000139;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000023164.1|UniProtKB=H2XVE2 H2XVE2 LOC108949285 PTHR24302:SF15 CYTOCHROME P450 FAMILY 3 FATTY-ACID PEROXYGENASE oxygenase#PC00177;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000005674.3|UniProtKB=F6YXZ3 F6YXZ3 LOC100180566 PTHR13707:SF23 KETOACID-COENZYME A TRANSFERASE SUCCINYL-COA:3-KETOACID-COENZYME A TRANSFERASE transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824 cellular metabolic process#GO:0044237;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152 transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000004262.3|UniProtKB=F7BNW5 F7BNW5 LOC100179870 PTHR10804:SF11 PROTEASE FAMILY M24 METHIONYL AMINOPEPTIDASE, AMINOPEPTIDASE P PROLIFERATION-ASSOCIATED PROTEIN 2G4 protease#PC00190 CIOIN|Ensembl=ENSCING00000005537.3|UniProtKB=F6RIG9 F6RIG9 PTHR12707:SF0 PINN PININ ribonucleoprotein complex#GO:1990904;catalytic step 2 spliceosome#GO:0071013;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000007089.3|UniProtKB=F6W8M0 F6W8M0 PTHR10766:SF177 TRANSMEMBRANE 9 SUPERFAMILY PROTEIN TRANSMEMBRANE 9 SUPERFAMILY MEMBER 1 localization#GO:0051179;localization within membrane#GO:0051668;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;protein localization to membrane#GO:0072657;cellular process#GO:0009987;protein localization#GO:0008104 cellular anatomical entity#GO:0110165;membrane#GO:0016020 transporter#PC00227 CIOIN|Ensembl=ENSCING00000003627.3|UniProtKB=F6TJJ7 F6TJJ7 PTHR24345:SF93 SERINE/THREONINE-PROTEIN KINASE PLK SERINE_THREONINE-PROTEIN KINASE PLK1 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;mitotic spindle organization#GO:0007052;microtubule-based process#GO:0007017;organelle organization#GO:0006996;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;cell cycle#GO:0007049;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;spindle organization#GO:0007051;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cellular process#GO:0009987;mitotic cell cycle process#GO:1903047 supramolecular complex#GO:0099080;spindle pole#GO:0000922;microtubule organizing center#GO:0005815;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;kinetochore#GO:0000776;condensed chromosome, centromeric region#GO:0000779;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;chromosome#GO:0005694;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;chromosomal region#GO:0098687;cytoskeleton#GO:0005856;spindle#GO:0005819 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000020376.1|UniProtKB=H2XRB5 H2XRB5 PTHR43053:SF4 GLYCOSIDASE FAMILY 31 MYOGENESIS-REGULATING GLYCOSIDASE glucosidase#PC00108 CIOIN|Ensembl=ENSCING00000008811.3|UniProtKB=F7BJL5 F7BJL5 PTHR11346:SF176 GALECTIN 32 KDA BETA-GALACTOSIDE-BINDING LECTIN LEC-3 carbohydrate binding#GO:0030246;binding#GO:0005488 extracellular matrix protein#PC00102 CIOIN|Ensembl=ENSCING00000008605.3|UniProtKB=F6TPB1 F6TPB1 LOC100178921 PTHR31443:SF3 FAMILY NOT NAMED SUBFAMILY NOT NAMED CIOIN|Ensembl=ENSCING00000003568.3|UniProtKB=F6YSJ8 F6YSJ8 LOC100180617 PTHR31539:SF1 CENTROSOMAL PROTEIN OF 19K CEP19 CENTROSOMAL PROTEIN OF 19 KDA vesicle targeting, to, from or within Golgi#GO:0048199;cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;cilium assembly#GO:0060271;organelle localization#GO:0051640;cell projection organization#GO:0030030;vesicle localization#GO:0051648;transport#GO:0006810;microtubule cytoskeleton organization#GO:0000226;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;vesicle targeting, trans-Golgi to periciliary membrane compartment#GO:0097712;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;vesicle targeting#GO:0006903;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;establishment of localization#GO:0051234;organelle organization#GO:0006996;establishment of vesicle localization#GO:0051650;establishment of localization in cell#GO:0051649;cytoskeleton organization#GO:0007010;plasma membrane bounded cell projection assembly#GO:0120031;establishment of organelle localization#GO:0051656 spindle pole#GO:0000922;microtubule organizing center#GO:0005815;cellular anatomical entity#GO:0110165;centriole#GO:0005814;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;ciliary basal body#GO:0036064;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;cell projection#GO:0042995;cilium#GO:0005929;spindle#GO:0005819 CIOIN|Ensembl=ENSCING00000001459.3|UniProtKB=F6VKM8 F6VKM8 LOC100178595 PTHR12374:SF20 TRANSCRIPTIONAL ADAPTOR 2 ADA2 -RELATED TRANSCRIPTIONAL ADAPTER 2-ALPHA molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;binding#GO:0005488;chromatin binding#GO:0003682;protein-macromolecule adaptor activity#GO:0030674;transcription coactivator activity#GO:0003713;protein-containing complex binding#GO:0044877 protein-DNA complex organization#GO:0071824;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;cellular component organization#GO:0016043;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;protein-containing complex organization#GO:0043933;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;chromatin remodeling#GO:0006338;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218 CIOIN|Ensembl=ENSCING00000001679.3|UniProtKB=F6X882 F6X882 PTHR12549:SF38 JMJC DOMAIN-CONTAINING HISTONE DEMETHYLATION PROTEIN JMJC DOMAIN-CONTAINING HISTONE DEMETHYLASE 2, ISOFORM A histone modifying activity#GO:0140993;nucleic acid binding#GO:0003676;histone demethylase activity#GO:0032452;binding#GO:0005488;catalytic activity#GO:0003824;protein-macromolecule adaptor activity#GO:0030674;transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;demethylase activity#GO:0032451;molecular adaptor activity#GO:0060090;chromatin DNA binding#GO:0031490;chromatin binding#GO:0003682;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;protein-containing complex binding#GO:0044877;catalytic activity, acting on a protein#GO:0140096 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;histone deacetylase complex#GO:0000118;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 chromatin/chromatin-binding, or -regulatory protein#PC00077;histone modifying enzyme#PC00261 CIOIN|Ensembl=ENSCING00000021576.1|UniProtKB=H2XKW2 H2XKW2 PTHR11806:SF0 GLUCOSE INHIBITED DIVISION PROTEIN A PROTEIN MTO1 HOMOLOG, MITOCHONDRIAL nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;flavin adenine dinucleotide binding#GO:0050660;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;RNA modification#GO:0009451;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;tRNA modification#GO:0006400;ncRNA metabolic process#GO:0034660;tRNA methylation#GO:0030488;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;tRNA wobble uridine modification#GO:0002098;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;methylation#GO:0032259;macromolecule methylation#GO:0043414;RNA methylation#GO:0001510 CIOIN|Ensembl=ENSCING00000006884.3|UniProtKB=F6YTY3 F6YTY3 LOC100187212 PTHR21452:SF4 EXPORTIN-6 EXPORTIN-6 cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;nitrogen compound transport#GO:0071705;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;nuclear export#GO:0051168;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;protein transport#GO:0015031;protein export from nucleus#GO:0006611;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;nuclear transport#GO:0051169 CIOIN|Ensembl=ENSCING00000015414.2|UniProtKB=F6X7Y3 F6X7Y3 PTHR19300:SF61 BETA-1,4-GALACTOSYLTRANSFERASE BETA-1,4-N-ACETYLGALACTOSAMINYLTRANSFERASE galactosyltransferase activity#GO:0008378;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 glycosylation#GO:0070085;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000009313.3|UniProtKB=F6ZMT5 F6ZMT5 PTHR24055:SF598 MITOGEN-ACTIVATED PROTEIN KINASE STRESS-ACTIVATED PROTEIN KINASE JNK transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;signaling#GO:0023052 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Integrin signalling pathway#P00034>Jnk#P00951;TGF-beta signaling pathway#P00052>JNK#P01284;Oxidative stress response#P00046>JNK1/2#P01129;Ras Pathway#P04393>JNK#P04572;Angiogenesis#P00005>JNK1#P00221;Interferon-gamma signaling pathway#P00035>Serine kinase#P00955;Alzheimer disease-amyloid secretase pathway#P00003>MAPK#P00099;EGF receptor signaling pathway#P00018>JNK1-3#P00545;Apoptosis signaling pathway#P00006>JNK#P00274;Toll receptor signaling pathway#P00054>JNK#P01375;Parkinson disease#P00049>SAPK#P01219;FGF signaling pathway#P00021>JNK1-3#P00628;FAS signaling pathway#P00020>JNK#P00615 CIOIN|Ensembl=ENSCING00000013192.2|UniProtKB=F6VTR4 F6VTR4 PTHR23320:SF158 MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MS4A -RELATED CREB-BINDING PROTEIN-LIKE ISOFORM X1 transporter#PC00227 CIOIN|Ensembl=ENSCING00000009082.3|UniProtKB=F6QEJ1 F6QEJ1 PTHR47490:SF2 PROTEIN BLISTER PROTEIN BLISTER CIOIN|Ensembl=ENSCING00000004189.3|UniProtKB=F7A6C5 F7A6C5 PTHR24179:SF21 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 12 MYOSIN BINDING SUBUNIT, ISOFORM O phosphatase regulator activity#GO:0019208;enzyme inhibitor activity#GO:0004857;molecular function inhibitor activity#GO:0140678;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 phosphatase modulator#PC00184 CIOIN|Ensembl=ENSCING00000004697.3|UniProtKB=F6QNI1 F6QNI1 LOC100184566 PTHR12316:SF17 NINJURIN-RELATED NINJURIN C, ISOFORM D cell adhesion#GO:0007155;cellular process#GO:0009987 cell adhesion molecule#PC00069 CIOIN|Ensembl=ENSCING00000024502.1|UniProtKB=H2XVY2 H2XVY2 PTHR32026:SF10 METHYLTRANSFERASE-LIKE PROTEIN 24 METHYLTRANSFERASE-LIKE PROTEIN 24-RELATED methyltransferase#PC00155 CIOIN|Ensembl=ENSCING00000011421.2|UniProtKB=F7AWY7 F7AWY7 LOC100182236 PTHR43975:SF2 ZGC:101858 EG:BACR7A4.14 PROTEIN-RELATED CIOIN|Ensembl=ENSCING00000007001.3|UniProtKB=F6SAH1 F6SAH1 PTHR24329:SF337 HOMEOBOX PROTEIN ARISTALESS ARISTALESS RELATED HOMEOBOX sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 CIOIN|Ensembl=ENSCING00000002306.3|UniProtKB=F6PP79 F6PP79 PTHR24043:SF8 SCAVENGER RECEPTOR CLASS F EGF-LIKE DOMAIN-CONTAINING PROTEIN membrane traffic protein#PC00150 CIOIN|Ensembl=ENSCING00000006646.3|UniProtKB=F6XA93 F6XA93 PTHR21444:SF14 COILED-COIL DOMAIN-CONTAINING PROTEIN 180 COILED-COIL DOMAIN-CONTAINING PROTEIN 180 CIOIN|Ensembl=ENSCING00000014830.2|UniProtKB=F6S8S3 F6S8S3 LOC100182417 PTHR13242:SF0 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT L macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;translation#GO:0006412;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;translational initiation#GO:0006413;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;eukaryotic translation initiation factor 3 complex#GO:0005852;intracellular anatomical structure#GO:0005622 translation initiation factor#PC00224;translation factor#PC00223;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000007050.3|UniProtKB=F6ZBW6 F6ZBW6 PTHR15286:SF6 RAS-ASSOCIATING DOMAIN CONTAINING PROTEIN GH01133P scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000005457.3|UniProtKB=F6UTV1 F6UTV1 PTHR11117:SF2 SUCCINYL-COA LIGASE SUBUNIT ALPHA SUCCINATE--COA LIGASE [ADP_GDP-FORMING] SUBUNIT ALPHA, MITOCHONDRIAL ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877 aerobic respiration#GO:0009060;cellular respiration#GO:0045333;generation of precursor metabolites and energy#GO:0006091;cellular metabolic process#GO:0044237;cellular process#GO:0009987;tricarboxylic acid cycle#GO:0006099;energy derivation by oxidation of organic compounds#GO:0015980;primary metabolic process#GO:0044238;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622 ligase#PC00142;metabolite interconversion enzyme#PC00262 TCA cycle#P00051>Succinyl CoA Synthetase#P01274 CIOIN|Ensembl=ENSCING00000012232.2|UniProtKB=F7B5X2 F7B5X2 LOC100182860 PTHR42721:SF42 SUGAR HYDROLASE-RELATED FIBRONECTIN TYPE III-LIKE DOMAIN-CONTAINING PROTEIN hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 polysaccharide metabolic process#GO:0005976;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;carbohydrate catabolic process#GO:0016052;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;cellular process#GO:0009987;carbohydrate metabolic process#GO:0005975;cell wall organization or biogenesis#GO:0071554;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 glucosidase#PC00108;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000020850.1|UniProtKB=H2XQ56 H2XQ56 PTHR10779:SF3 DYNEIN LIGHT CHAIN ROADBLOCK DYNEIN LIGHT CHAIN ROADBLOCK-TYPE 2 protein binding#GO:0005515;binding#GO:0005488 microtubule-based movement#GO:0007018;cellular process#GO:0009987;microtubule-based process#GO:0007017 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;microtubule cytoskeleton#GO:0015630;dynein complex#GO:0030286;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic dynein complex#GO:0005868;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;microtubule or microtubule-binding cytoskeletal protein#PC00157 CIOIN|Ensembl=ENSCING00000006631.3|UniProtKB=F6UP66 F6UP66 LOC100180098 PTHR21308:SF1 PHYTANOYL-COA ALPHA-HYDROXYLASE PHYTANOYL-COA DIOXYGENASE, PEROXISOMAL hydroxylase#PC00122 CIOIN|Ensembl=ENSCING00000009501.3|UniProtKB=F6Y8Y8 F6Y8Y8 PTHR10501:SF13 U1 SMALL NUCLEAR RIBONUCLEOPROTEIN A/U2 SMALL NUCLEAR RIBONUCLEOPROTEIN B U1 SMALL NUCLEAR RIBONUCLEOPROTEIN A nucleic acid binding#GO:0003676;RNA binding#GO:0003723;snRNA binding#GO:0017069;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704 ribonucleoprotein complex#GO:1990904;spliceosomal snRNP complex#GO:0097525;small nuclear ribonucleoprotein complex#GO:0030532;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;U1 snRNP#GO:0005685;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA splicing factor#PC00148;RNA processing factor#PC00147;RNA metabolism protein#PC00031 mRNA splicing#P00058>U2#P01478;mRNA splicing#P00058>U1#P01479 CIOIN|Ensembl=ENSCING00000009294.3|UniProtKB=F7B9T1 F7B9T1 PTHR12409:SF0 PREFOLDIN SUBUNIT 3 PREFOLDIN SUBUNIT 3 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;microtubule-based process#GO:0007017;protein-containing complex organization#GO:0043933;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;cellular process#GO:0009987 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622 chaperone#PC00072 CIOIN|Ensembl=ENSCING00000006284.3|UniProtKB=A0A1W2W1I3 A0A1W2W1I3 LOC100179166 PTHR31829:SF0 PYRIDOXAL 5'-PHOSPHATE SYNTHASE SUBUNIT SNZ1-RELATED PYRIDOXAL 5'-PHOSPHATE SYNTHASE SUBUNIT SNZ1-RELATED lyase activity#GO:0016829;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;organic hydroxy compound metabolic process#GO:1901615;heterocycle metabolic process#GO:0046483;organophosphate biosynthetic process#GO:0090407;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic hydroxy compound biosynthetic process#GO:1901617;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;pyridine-containing compound metabolic process#GO:0072524;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;small molecule biosynthetic process#GO:0044283;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704 CIOIN|Ensembl=ENSCING00000018831.1|UniProtKB=H2Y286 H2Y286 zf(u1like)-1 PTHR31394:SF1 TRANSMEMBRANE PROTEIN 199 TRANSMEMBRANE PROTEIN 199 cellular anatomical entity#GO:0110165;endomembrane system#GO:0012505 CIOIN|Ensembl=ENSCING00000011929.2|UniProtKB=F6VB34 F6VB34 PTHR28348:SF1 UPF0193 PROTEIN EVG1 UPF0193 PROTEIN EVG1 CIOIN|Ensembl=ENSCING00000007074.3|UniProtKB=F6WVT9 F6WVT9 PTHR24356:SF163 SERINE/THREONINE-PROTEIN KINASE 3-PHOSPHOINOSITIDE-DEPENDENT PROTEIN KINASE 1-RELATED transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular process#GO:0009987;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PDK1#P00831;Ras Pathway#P04393>PDK#P04555;CCKR signaling map#P06959>PDPK1#P07162;PI3 kinase pathway#P00048>PDK1 ACT#P01190;PI3 kinase pathway#P00048>PDK1#P01196;p53 pathway feedback loops 2#P04398>PDK1/2#P04656;p53 pathway#P00059>PDK1/2#P04616;Interleukin signaling pathway#P00036>PDK1/2#P00985;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>PDK1/2#P00903;PDGF signaling pathway#P00047>PDK1/2#P01164;PI3 kinase pathway#P00048>P110ACT#P01177 CIOIN|Ensembl=ENSCING00000004589.3|UniProtKB=F6U7F8 F6U7F8 PTHR24039:SF58 FIBRILLIN-RELATED EGF-LIKE DOMAIN-CONTAINING PROTEIN extracellular matrix structural protein#PC00103 CIOIN|Ensembl=ENSCING00000007679.3|UniProtKB=F6T718 F6T718 PTHR24058:SF112 DUAL SPECIFICITY PROTEIN KINASE DUAL SPECIFICITY TYROSINE-PHOSPHORYLATION-REGULATED KINASE 3 HOMOLOG-RELATED transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;protein phosphorylation#GO:0006468;cellular process#GO:0009987;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;peptidyl-threonine phosphorylation#GO:0018107;nitrogen compound metabolic process#GO:0006807;peptidyl-serine modification#GO:0018209;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000015798.2|UniProtKB=F6SIS7 F6SIS7 PTHR28617:SF1 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 77 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 77 structural protein#PC00211 CIOIN|Ensembl=ENSCING00000007616.3|UniProtKB=F6X5N8 F6X5N8 LOC494423 PTHR11388:SF157 ORGANIC ANION TRANSPORTER SOLUTE CARRIER ORGANIC ANION TRANSPORTER FAMILY MEMBER 2A1-LIKE secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 localization#GO:0051179;organic substance transport#GO:0071702;establishment of localization#GO:0051234;organic anion transport#GO:0015711;transport#GO:0006810 basal plasma membrane#GO:0009925;basolateral plasma membrane#GO:0016323;plasma membrane region#GO:0098590;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;basal part of cell#GO:0045178;plasma membrane#GO:0005886 transporter#PC00227 CIOIN|Ensembl=ENSCING00000006816.3|UniProtKB=F6TZR8 F6TZR8 PTHR10024:SF227 SYNAPTOTAGMIN SYNAPTOTAGMIN 1 cation binding#GO:0043169;small molecule binding#GO:0036094;binding#GO:0005488;phosphatidylserine binding#GO:0001786;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;protein binding#GO:0005515;clathrin binding#GO:0030276;lipid binding#GO:0008289;ion binding#GO:0043167;phospholipid binding#GO:0005543;SNARE binding#GO:0000149 cellular localization#GO:0051641;synaptic vesicle cycle#GO:0099504;synaptic vesicle endocytosis#GO:0048488;transport#GO:0006810;regulation of biological process#GO:0050789;regulated exocytosis#GO:0045055;synaptic vesicle recycling#GO:0036465;chemical synaptic transmission#GO:0007268;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;secretion#GO:0046903;neurotransmitter transport#GO:0006836;synaptic signaling#GO:0099536;signal release#GO:0023061;calcium-ion regulated exocytosis#GO:0017156;cell-cell signaling#GO:0007267;signaling#GO:0023052;synaptic vesicle exocytosis#GO:0016079;secretion by cell#GO:0032940;neurotransmitter secretion#GO:0007269;endocytosis#GO:0006897;trans-synaptic signaling#GO:0099537;vesicle-mediated transport#GO:0016192;cell communication#GO:0007154;cellular process#GO:0009987;localization#GO:0051179;signal release from synapse#GO:0099643;exocytosis#GO:0006887;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;import into cell#GO:0098657;export from cell#GO:0140352;vesicle-mediated transport in synapse#GO:0099003 intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;transport vesicle#GO:0030133;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 membrane trafficking regulatory protein#PC00151 Synaptic vesicle trafficking#P05734>Synaptotagmin#P05769 CIOIN|Ensembl=ENSCING00000008936.3|UniProtKB=F6Q9R4 F6Q9R4 LOC100183423 PTHR21255:SF27 T-COMPLEX-ASSOCIATED-TESTIS-EXPRESSED 1/ DYNEIN LIGHT CHAIN DYNEIN LIGHT CHAIN TCTEX-TYPE PROTEIN 2 protein binding#GO:0005515;binding#GO:0005488 microtubule-based movement#GO:0007018;cellular process#GO:0009987;microtubule-based process#GO:0007017 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;microtubule cytoskeleton#GO:0015630;dynein complex#GO:0030286;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic dynein complex#GO:0005868;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;microtubule or microtubule-binding cytoskeletal protein#PC00157 CIOIN|Ensembl=ENSCING00000009452.3|UniProtKB=F7AZ78 F7AZ78 PTHR46693:SF1 ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 15 ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 15 CIOIN|Ensembl=ENSCING00000001987.3|UniProtKB=F6XGB5 F6XGB5 LOC100181806 PTHR15099:SF2 PROTEIN PM1 TRANSMEMBRANE PROTEIN 11, MITOCHONDRIAL cellular component organization or biogenesis#GO:0071840;membrane organization#GO:0061024;organelle organization#GO:0006996;cellular component organization#GO:0016043;mitochondrial membrane organization#GO:0007006;mitochondrion organization#GO:0007005;cellular process#GO:0009987;inner mitochondrial membrane organization#GO:0007007 envelope#GO:0031975;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227 CIOIN|Ensembl=ENSCING00000009345.3|UniProtKB=F7B5G0 F7B5G0 PTHR22999:SF40 PX SERINE/THREONINE KINASE PXK PX DOMAIN-CONTAINING PROTEIN KINASE-LIKE PROTEIN lipid binding#GO:0008289;phosphatidylinositol binding#GO:0035091;phospholipid binding#GO:0005543;binding#GO:0005488 endosomal transport#GO:0016197;cellular localization#GO:0051641;negative regulation of biological process#GO:0048519;macromolecule localization#GO:0033036;protein targeting to vacuole#GO:0006623;transport#GO:0006810;nitrogen compound transport#GO:0071705;regulation of localization#GO:0032879;endosome to lysosome transport#GO:0008333;protein targeting to lysosome#GO:0006622;lysosomal transport#GO:0007041;establishment of protein localization#GO:0045184;regulation of biological process#GO:0050789;organic substance transport#GO:0071702;regulation of transport#GO:0051049;establishment of localization#GO:0051234;regulation of molecular function#GO:0065009;regulation of monoatomic ion transport#GO:0043269;protein localization to organelle#GO:0033365;establishment of protein localization to vacuole#GO:0072666;vacuolar transport#GO:0007034;protein localization to vacuole#GO:0072665;protein targeting#GO:0006605;establishment of protein localization to organelle#GO:0072594;vesicle-mediated transport#GO:0016192;negative regulation of transport#GO:0051051;cellular process#GO:0009987;protein localization#GO:0008104;localization#GO:0051179;protein localization to lysosome#GO:0061462;cellular macromolecule localization#GO:0070727;protein transport#GO:0015031;negative regulation of monoatomic ion transport#GO:0043271;biological regulation#GO:0065007;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;early endosome to late endosome transport#GO:0045022;negative regulation of molecular function#GO:0044092 endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;early endosome#GO:0005769;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;late endosome#GO:0005770;plasma membrane#GO:0005886 CIOIN|Ensembl=ENSCING00000011258.1|UniProtKB=F6YTE8 F6YTE8 PTHR24034:SF200 EGF-LIKE DOMAIN-CONTAINING PROTEIN EGF-LIKE AND EMI DOMAIN-CONTAINING PROTEIN 1 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 CIOIN|Ensembl=ENSCING00000015298.2|UniProtKB=F6UHV9 F6UHV9 PTHR10625:SF14 HISTONE DEACETYLASE HDAC1-RELATED HISTONE DEACETYLASE 8 histone modifying activity#GO:0140993;histone deacetylase activity#GO:0004407;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;deacetylase activity#GO:0019213;catalytic activity, acting on a protein#GO:0140096 negative regulation of gene expression#GO:0010629;negative regulation of cellular metabolic process#GO:0031324;protein-DNA complex organization#GO:0071824;negative regulation of biological process#GO:0048519;negative regulation of biosynthetic process#GO:0009890;heterochromatin formation#GO:0031507;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;negative regulation of gene expression, epigenetic#GO:0045814;cellular process#GO:0009987;epigenetic regulation of gene expression#GO:0040029;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;negative regulation of macromolecule biosynthetic process#GO:0010558;heterochromatin organization#GO:0070828;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;protein-containing complex organization#GO:0043933;regulation of cellular process#GO:0050794;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;chromatin remodeling#GO:0006338;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 Wnt signaling pathway#P00057>Histone deacetylase#P01472 CIOIN|Ensembl=ENSCING00000019647.1|UniProtKB=H2XQM2 H2XQM2 LOC100183646 PTHR46194:SF1 PEPTIDYL-TRNA HYDROLASE PTRHD1-RELATED PEPTIDYL-TRNA HYDROLASE PTRHD1-RELATED CIOIN|Ensembl=ENSCING00000007835.3|UniProtKB=F6W6R6 F6W6R6 LOC100176963 PTHR11699:SF211 ALDEHYDE DEHYDROGENASE-RELATED ALDEHYDE DEHYDROGENASE FAMILY 16 MEMBER A1 dehydrogenase#PC00092;oxidoreductase#PC00176 5-Hydroxytryptamine degredation#P04372>Aldehyde Dehydrogenase#P04402;Ornithine degradation#P02758>Aminobutyraldehyde dehydrogenase#P03055;Phenylethylamine degradation#P02766>Phenylacetaldehyde dehydrogenase#P03102 CIOIN|Ensembl=ENSCING00000024090.1|UniProtKB=H2Y3G1 H2Y3G1 LOC100179371 PTHR24034:SF209 EGF-LIKE DOMAIN-CONTAINING PROTEIN EGF-LIKE DOMAIN-CONTAINING PROTEIN extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 CIOIN|Ensembl=ENSCING00000018253.1|UniProtKB=H2Y255 H2Y255 PTHR11348:SF17 CONNECTIVE TISSUE GROWTH FACTOR-RELATED CCN carbohydrate derivative binding#GO:0097367;integrin binding#GO:0005178;binding#GO:0005488;heparin binding#GO:0008201;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;glycosaminoglycan binding#GO:0005539;signaling receptor binding#GO:0005102 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;positive regulation of cell differentiation#GO:0045597;cell communication#GO:0007154;cell adhesion#GO:0007155;cellular process#GO:0009987;regulation of cell differentiation#GO:0045595;positive regulation of developmental process#GO:0051094;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;biological regulation#GO:0065007;signaling#GO:0023052;positive regulation of biological process#GO:0048518 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;extracellular space#GO:0005615;extracellular region#GO:0005576 growth factor#PC00112 CIOIN|Ensembl=ENSCING00000018489.1|UniProtKB=H2XM50 H2XM50 PTHR12879:SF8 SPHINGOLIPID DELTA 4 DESATURASE/C-4 HYDROXYLASE PROTEIN DES2 SPHINGOLIPID DELTA(4)-DESATURASE DES1 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 lipid metabolic process#GO:0006629;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;membrane lipid biosynthetic process#GO:0046467;sphingolipid metabolic process#GO:0006665;ceramide metabolic process#GO:0006672;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;membrane lipid metabolic process#GO:0006643;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;ceramide biosynthetic process#GO:0046513;cellular lipid metabolic process#GO:0044255;amide metabolic process#GO:0043603;sphingolipid biosynthetic process#GO:0030148;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 hydroxylase#PC00122 CIOIN|Ensembl=ENSCING00000003131.3|UniProtKB=I6L237 I6L237 LOC100183233 PTHR12592:SF0 ATP-DEPENDENT (S)-NAD(P)H-HYDRATE DEHYDRATASE FAMILY MEMBER ATP-DEPENDENT (S)-NAD(P)H-HYDRATE DEHYDRATASE cellular metabolic process#GO:0044237;cellular process#GO:0009987;metabolic process#GO:0008152 dehydratase#PC00091;lyase#PC00144 CIOIN|Ensembl=ENSCING00000020439.1|UniProtKB=H2XL66 H2XL66 PTHR22948:SF76 TUDOR DOMAIN CONTAINING PROTEIN FI20010P1-RELATED scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000021424.1|UniProtKB=H2XX13 H2XX13 PTHR10155:SF5 PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT SUPPRESSOR OF CYTOKINE SIGNALING 7 enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207 lipid metabolic process#GO:0006629;phospholipid biosynthetic process#GO:0008654;organophosphate biosynthetic process#GO:0090407;phosphatidylinositol biosynthetic process#GO:0006661;glycerolipid biosynthetic process#GO:0045017;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;phosphatidylinositol metabolic process#GO:0046488;glycerophospholipid metabolic process#GO:0006650;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;phosphatidylinositol phosphate biosynthetic process#GO:0046854;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;glycerophospholipid biosynthetic process#GO:0046474;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;phosphatidylinositol 3-kinase complex#GO:0005942;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;membrane#GO:0016020;transferase complex, transferring phosphorus-containing groups#GO:0061695;extrinsic component of membrane#GO:0019898 kinase modulator#PC00140 Interferon-gamma signaling pathway#P00035>SOCS#P00956;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>SOCS#P00879 CIOIN|Ensembl=ENSCING00000002456.3|UniProtKB=A0A1W3JT00 A0A1W3JT00 LOC100187105 PTHR15907:SF182 DUF614 FAMILY PROTEIN-RELATED PROTEIN PLANT CADMIUM RESISTANCE 1-RELATED CIOIN|Ensembl=ENSCING00000024726.1|UniProtKB=H2Y3F7 H2Y3F7 PTHR24291:SF201 CYTOCHROME P450 FAMILY 4 CYTOCHROME P450, FAMILY 4, SUBFAMILY B, POLYPEPTIDE 7 oxygenase#PC00177;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000013578.2|UniProtKB=F6XNH0 F6XNH0 PTHR13429:SF5 FERM DOMAIN (PROTEIN4.1-EZRIN-RADIXIN-MOESIN) FAMILY PROTEIN EXPANDED regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;positive regulation of signal transduction#GO:0009967;positive regulation of cell communication#GO:0010647;regulation of signaling#GO:0023051;biological regulation#GO:0065007;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;regulation of intracellular signal transduction#GO:1902531;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522 plasma membrane region#GO:0098590;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;cytoplasmic side of plasma membrane#GO:0009898;apical plasma membrane#GO:0016324;plasma membrane#GO:0005886;apical part of cell#GO:0045177 CIOIN|Ensembl=ENSCING00000007155.3|UniProtKB=F7BGG9 F7BGG9 PTHR19300:SF61 BETA-1,4-GALACTOSYLTRANSFERASE BETA-1,4-N-ACETYLGALACTOSAMINYLTRANSFERASE galactosyltransferase activity#GO:0008378;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 glycosylation#GO:0070085;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000004227.2|UniProtKB=F6YGK4 F6YGK4 PTHR10288:SF338 KH DOMAIN CONTAINING RNA BINDING PROTEIN IGF-II MRNA-BINDING PROTEIN, ISOFORM L nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159;mRNA 3'-UTR binding#GO:0003730 developmental process#GO:0032502;multicellular organism development#GO:0007275;nervous system development#GO:0007399;regulation of biological process#GO:0050789;system development#GO:0048731;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000004681.3|UniProtKB=F6QSR3 F6QSR3 PTHR18934:SF221 ATP-DEPENDENT RNA HELICASE ATP-DEPENDENT RNA HELICASE DHX34-RELATED nucleic acid binding#GO:0003676;RNA binding#GO:0003723;helicase activity#GO:0004386;ATP-dependent activity#GO:0140657;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;catalytic activity, acting on a nucleic acid#GO:0140640 cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 RNA helicase#PC00032 CIOIN|Ensembl=ENSCING00000020062.1|UniProtKB=H2XYT3 H2XYT3 LOC100180383 PTHR23417:SF16 3-DEOXY-D-MANNO-OCTULOSONIC-ACID TRANSFERASE/TRNA GUANINE-N 7 - -METHYLTRANSFERASE TRNA (GUANINE-N(7)-)-METHYLTRANSFERASE tRNA methyltransferase activity#GO:0008175;catalytic activity, acting on RNA#GO:0140098;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;RNA methyltransferase activity#GO:0008173 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA modification#GO:0009451;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;tRNA modification#GO:0006400;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;macromolecule methylation#GO:0043414;tRNA methylation#GO:0030488;organic cyclic compound metabolic process#GO:1901360;methylation#GO:0032259;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;RNA methylation#GO:0001510;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 methyltransferase complex#GO:0034708;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular anatomical structure#GO:0005622 RNA processing factor#PC00147;RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000020197.1|UniProtKB=H2XNG8 H2XNG8 PTHR11767:SF111 INWARD RECTIFIER POTASSIUM CHANNEL INWARD RECTIFIER POTASSIUM CHANNEL 2-LIKE monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated potassium channel activity#GO:0005249;channel activity#GO:0015267;transporter activity#GO:0005215;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;ligand-gated monoatomic cation channel activity#GO:0099094;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;ligand-gated channel activity#GO:0022834 regulation of monoatomic ion transmembrane transport#GO:0034765;regulation of transmembrane transport#GO:0034762;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;regulation of localization#GO:0032879;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;localization#GO:0051179;regulation of biological process#GO:0050789;import across plasma membrane#GO:0098739;regulation of transport#GO:0051049;establishment of localization#GO:0051234;regulation of cellular process#GO:0050794;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;monoatomic cation transport#GO:0006812;regulation of monoatomic ion transport#GO:0043269;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;import into cell#GO:0098657;potassium ion transport#GO:0006813;potassium ion import across plasma membrane#GO:1990573 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 CIOIN|Ensembl=ENSCING00000011469.1|UniProtKB=F6SK07 F6SK07 PTHR22906:SF49 PROPERDIN COADHESIN-LIKE CIOIN|Ensembl=ENSCING00000015188.2|UniProtKB=F6XXQ7 F6XXQ7 LOC100175264 PTHR43675:SF8 ARSENITE METHYLTRANSFERASE ARSENITE METHYLTRANSFERASE methyltransferase activity#GO:0008168;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824 methyltransferase#PC00155;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000006320.3|UniProtKB=F6PYJ8 F6PYJ8 PTHR10196:SF68 SUGAR KINASE GLYCEROL KINASE 5-RELATED transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301 organic hydroxy compound metabolic process#GO:1901615;lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;triglyceride metabolic process#GO:0006641;organophosphate biosynthetic process#GO:0090407;cellular metabolic process#GO:0044237;alcohol metabolic process#GO:0006066;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;acylglycerol metabolic process#GO:0006639;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;carbohydrate derivative biosynthetic process#GO:1901137;neutral lipid metabolic process#GO:0006638;glycerolipid metabolic process#GO:0046486;glycerol-3-phosphate metabolic process#GO:0006072;organophosphate metabolic process#GO:0019637;phosphorylation#GO:0016310;cellular lipid metabolic process#GO:0044255;carbohydrate metabolic process#GO:0005975;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 carbohydrate kinase#PC00065 CIOIN|Ensembl=ENSCING00000000475.3|UniProtKB=F6YVQ9 F6YVQ9 LOC100185717 PTHR24072:SF156 RHO FAMILY GTPASE RHO-RELATED BTB DOMAIN CONTAINING, ISOFORM B GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;enzyme binding#GO:0019899;ribonucleoside triphosphate phosphatase activity#GO:0017111;kinase binding#GO:0019900;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;protein kinase binding#GO:0019901;anion binding#GO:0043168;ion binding#GO:0043167 establishment or maintenance of cell polarity#GO:0007163;regulation of anatomical structure morphogenesis#GO:0022603;regulation of organelle organization#GO:0033043;regulation of cellular component organization#GO:0051128;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of cytoskeleton organization#GO:0051493;regulation of cell shape#GO:0008360;regulation of biological quality#GO:0065008;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;cortical cytoskeleton organization#GO:0030865;biological regulation#GO:0065007;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;regulation of actin filament-based process#GO:0032970 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 small GTPase#PC00208 CIOIN|Ensembl=ENSCING00000004834.3|UniProtKB=F6TZD9 F6TZD9 PTHR10183:SF382 CALPAIN CALPAIN-15 cysteine-type peptidase activity#GO:0008234;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 cysteine protease#PC00081;protease#PC00190 CIOIN|Ensembl=ENSCING00000016078.2|UniProtKB=F6VJL7 F6VJL7 LOC100186399 PTHR10497:SF0 60S RIBOSOMAL PROTEIN L27 LARGE RIBOSOMAL SUBUNIT PROTEIN EL27 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic large ribosomal subunit#GO:0022625;large ribosomal subunit#GO:0015934;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000019565.1|UniProtKB=H2XT24 H2XT24 PTHR11096:SF1 RNA 3' TERMINAL PHOSPHATE CYCLASE RNA 3'-TERMINAL PHOSPHATE CYCLASE-LIKE PROTEIN catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;ligase activity#GO:0016874;cyclase activity#GO:0009975;nuclease activity#GO:0004518;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a nucleic acid#GO:0140640;endonuclease activity#GO:0004519;RNA nuclease activity#GO:0004540;RNA endonuclease activity#GO:0004521 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;ribosome biogenesis#GO:0042254;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000004106.3|UniProtKB=F6XVB0 F6XVB0 LOC100177413 PTHR45677:SF1 GLUTAMATE DECARBOXYLASE-RELATED ACIDIC AMINO ACID DECARBOXYLASE GADL1 lyase activity#GO:0016829;carboxy-lyase activity#GO:0016831;carbon-carbon lyase activity#GO:0016830;catalytic activity#GO:0003824 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 decarboxylase#PC00089 Gamma-aminobutyric acid synthesis#P04384>Glutamate decarboxylase#P04482 CIOIN|Ensembl=ENSCING00000019768.1|UniProtKB=H2Y1E7 H2Y1E7 PTHR10924:SF4 MAJOR FACILITATOR SUPERFAMILY PROTEIN-RELATED GH15861P tetrapyrrole binding#GO:0046906;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;binding#GO:0005488;organic cyclic compound binding#GO:0097159;heme binding#GO:0020037 localization#GO:0051179;organic substance transport#GO:0071702;metal ion transport#GO:0030001;establishment of localization#GO:0051234;transport#GO:0006810;monoatomic cation transport#GO:0006812;nitrogen compound transport#GO:0071705;iron ion transport#GO:0006826;transition metal ion transport#GO:0000041;monoatomic ion transport#GO:0006811 cellular anatomical entity#GO:0110165;membrane#GO:0016020 secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000024219.1|UniProtKB=H2XPE8 H2XPE8 PTHR46756:SF18 TRANSGELIN GAS2-LIKE PROTEIN PICKLED EGGS cytoskeletal protein binding#GO:0008092;molecular adaptor activity#GO:0060090;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;actin filament binding#GO:0051015;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779 cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987 supramolecular complex#GO:0099080;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;supramolecular fiber#GO:0099512;supramolecular polymer#GO:0099081;actin filament#GO:0005884;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085 CIOIN|Ensembl=ENSCING00000022511.1|UniProtKB=H2XKQ6 H2XKQ6 PTHR24033:SF218 EGF-LIKE DOMAIN-CONTAINING PROTEIN EGF-LIKE DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000023938.1|UniProtKB=H2XYI9 H2XYI9 PTHR13132:SF29 ALPHA- 1,6 -FUCOSYLTRANSFERASE ALPHA-(1,6)-FUCOSYLTRANSFERASE transferase activity#GO:0016740;fucosyltransferase activity#GO:0008417;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein glycosylation#GO:0006486;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein N-linked glycosylation#GO:0006487;protein metabolic process#GO:0019538;glycosylation#GO:0070085;glycoprotein metabolic process#GO:0009100;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 glycosyltransferase#PC00111 Notch signaling pathway#P00045>Neurotic#P01115 CIOIN|Ensembl=ENSCING00000022852.1|UniProtKB=H2XSN2 H2XSN2 LOC100182606 PTHR13374:SF3 DET1 HOMOLOG DE-ETIOLATED-1 HOMOLOG DET1 HOMOLOG molecular adaptor activity#GO:0060090;binding#GO:0005488;ubiquitin-like protein ligase binding#GO:0044389;protein-macromolecule adaptor activity#GO:0030674;protein binding#GO:0005515;ubiquitin ligase-substrate adaptor activity#GO:1990756;enzyme binding#GO:0019899;ubiquitin protein ligase binding#GO:0031625 positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of protein metabolic process#GO:0051246;regulation of catabolic process#GO:0009894;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of proteasomal protein catabolic process#GO:1901800;protein modification process#GO:0036211;regulation of protein catabolic process#GO:0042176;regulation of proteolysis involved in protein catabolic process#GO:1903050;post-translational protein modification#GO:0043687;positive regulation of proteolysis#GO:0045862;regulation of biological process#GO:0050789;positive regulation of metabolic process#GO:0009893;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;positive regulation of biological process#GO:0048518;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;positive regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032436;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;regulation of proteolysis#GO:0030162;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;positive regulation of proteolysis involved in protein catabolic process#GO:1903052;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;regulation of proteasomal protein catabolic process#GO:0061136;positive regulation of protein metabolic process#GO:0051247;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;positive regulation of catabolic process#GO:0009896;positive regulation of protein catabolic process#GO:0045732;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434;regulation of metabolic process#GO:0019222 protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cullin-RING ubiquitin ligase complex#GO:0031461;catalytic complex#GO:1902494;transferase complex#GO:1990234;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000005686.3|UniProtKB=F6XCH5 F6XCH5 hsp70 PTHR19375:SF551 HEAT SHOCK PROTEIN 70KDA HEAT SHOCK 70 KDA PROTEIN COGNATE 2 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 Hsp70 family chaperone#PC00027 Parkinson disease#P00049>Hsp70#P01208;Apoptosis signaling pathway#P00006>HSP70#P00321 CIOIN|Ensembl=ENSCING00000005431.3|UniProtKB=F6VIM5 F6VIM5 PTHR42985:SF45 SODIUM-COUPLED MONOCARBOXYLATE TRANSPORTER SODIUM_IODIDE COTRANSPORTER-LIKE symporter activity#GO:0015293;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 localization#GO:0051179;monoatomic cation transport#GO:0006812;sodium ion transport#GO:0006814;metal ion transport#GO:0030001;establishment of localization#GO:0051234;monoatomic ion transport#GO:0006811;transport#GO:0006810 secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000013289.2|UniProtKB=F7BLF3 F7BLF3 LOC100178668 PTHR13473:SF0 MITOCHONDRIAL RIBOSOMAL PROTEIN L48 LARGE RIBOSOMAL SUBUNIT PROTEIN ML48 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;mitochondrial ribosome#GO:0005761;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;organellar ribosome#GO:0000313;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;ribosome#GO:0005840 ribosomal protein#PC00202;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000017644.2|UniProtKB=F6S8N1 F6S8N1 LOC100177878 PTHR21642:SF6 CEREBRAL CAVERNOUS MALFORMATIONS PROTEIN 2 HOMOLOG CEREBRAL CAVERNOUS MALFORMATIONS 2 HARMONIN-HOMOLOGY DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000005008.3|UniProtKB=A0A1W2WKI9 A0A1W2WKI9 LOC100185384 PTHR10666:SF451 UBIQUITIN UBIQUITIN-LIKE PROTEIN 1-RIBOSOMAL PROTEIN ES31 FUSION PROTEIN enzyme binding#GO:0019899;protein binding#GO:0005515;ubiquitin protein ligase binding#GO:0031625;binding#GO:0005488;ubiquitin-like protein ligase binding#GO:0044389 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;protein modification by small protein conjugation#GO:0032446;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000002961.3|UniProtKB=F6R3U4 F6R3U4 PTHR12381:SF56 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN U FAMILY MEMBER B30.2_SPRY DOMAIN-CONTAINING PROTEIN-RELATED nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;alternative mRNA splicing, via spliceosome#GO:0000380;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000009199.3|UniProtKB=F6WNQ6 F6WNQ6 PTHR23354:SF62 NUCLEOLAR PROTEIN 7/ESTROGEN RECEPTOR COACTIVATOR-RELATED MUSTARD, ISOFORM V CIOIN|Ensembl=ENSCING00000008004.3|UniProtKB=F6VHL9 F6VHL9 PTHR46283:SF2 E3 UBIQUITIN-PROTEIN LIGASE MARCH5 AT07234P-RELATED transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;regulation of anatomical structure morphogenesis#GO:0022603;macromolecule metabolic process#GO:0043170;regulation of organelle organization#GO:0033043;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;regulation of cellular component organization#GO:0051128;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of mitochondrion organization#GO:0010821;nitrogen compound metabolic process#GO:0006807;biological regulation#GO:0065007;protein polyubiquitination#GO:0000209;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 envelope#GO:0031975;bounding membrane of organelle#GO:0098588;mitochondrial membrane#GO:0031966;intracellular membrane-bounded organelle#GO:0043231;mitochondrial outer membrane#GO:0005741;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000018368.1|UniProtKB=H2XX34 H2XX34 PTHR13245:SF14 RRP15-LIKE PROTEIN RRP15-LIKE PROTEIN cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;ribosomal large subunit biogenesis#GO:0042273;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;maturation of 5.8S rRNA#GO:0000460;maturation of LSU-rRNA#GO:0000470;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 ribonucleoprotein complex#GO:1990904;preribosome#GO:0030684;preribosome, large subunit precursor#GO:0030687;protein-containing complex#GO:0032991 CIOIN|Ensembl=ENSCING00000006059.3|UniProtKB=Q4H396 Q4H396 Ci-LAG1-like1 PTHR12560:SF0 LONGEVITY ASSURANCE FACTOR 1 LAG1 LD18904P transferase activity#GO:0016740;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity#GO:0003824;N-acyltransferase activity#GO:0016410 lipid metabolic process#GO:0006629;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;membrane lipid biosynthetic process#GO:0046467;sphingolipid metabolic process#GO:0006665;ceramide metabolic process#GO:0006672;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;membrane lipid metabolic process#GO:0006643;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;ceramide biosynthetic process#GO:0046513;cellular lipid metabolic process#GO:0044255;amide metabolic process#GO:0043603;sphingolipid biosynthetic process#GO:0030148;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000009021.3|UniProtKB=F6UUQ0 F6UUQ0 PTHR15532:SF5 FAMILY NOT NAMED SULFOTRANSFERASE DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000001388.3|UniProtKB=F6ZTU7 F6ZTU7 PTHR24127:SF1 ANKYRIN REPEAT AND EF-HAND DOMAIN-CONTAINING PROTEIN 1 ANKYRIN REPEAT AND EF-HAND DOMAIN-CONTAINING PROTEIN 1 CIOIN|Ensembl=ENSCING00000008806.3|UniProtKB=F7BJS1 F7BJS1 PTHR10963:SF55 GLYCOSYL HYDROLASE-RELATED GLYCOSIDE HYDROLASE FAMILY 16 PROTEIN glucosidase#PC00108;metabolite interconversion enzyme#PC00262;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000003977.3|UniProtKB=F6WKG4 F6WKG4 PTHR11972:SF208 NADPH OXIDASE DUAL OXIDASE-LIKE PROTEIN oxidoreductase activity, acting on NAD(P)H#GO:0016651;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 cellular metabolic process#GO:0044237;response to stimulus#GO:0050896;response to stress#GO:0006950;cellular process#GO:0009987;defense response#GO:0006952;metabolic process#GO:0008152 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;plasma membrane protein complex#GO:0098797;oxidoreductase complex#GO:1990204;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 oxidase#PC00175;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000002390.3|UniProtKB=F6R035 F6R035 LOC100180096 PTHR13034:SF2 DYNACTIN P62 SUBUNIT DYNACTIN SUBUNIT 4 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 CIOIN|Ensembl=ENSCING00000008693.3|UniProtKB=F6WZJ4 F6WZJ4 LOC100186901 PTHR21328:SF2 POLY ADP-RIBOSE POLYMERASE FAMILY, MEMBER PARP PROTEIN MONO-ADP-RIBOSYLTRANSFERASE PARP16 CIOIN|Ensembl=ENSCING00000006905.3|UniProtKB=F6YAD0 F6YAD0 PTHR13366:SF0 MALARIA ANTIGEN-RELATED HEAT REPEAT-CONTAINING PROTEIN 6 CIOIN|Ensembl=ENSCING00000011468.2|UniProtKB=F6ZU59 F6ZU59 PTHR22906:SF49 PROPERDIN COADHESIN-LIKE CIOIN|Ensembl=ENSCING00000000871.3|UniProtKB=F6QQK4 F6QQK4 LOC100182403 PTHR23220:SF133 INTEGRIN ALPHA INTEGRIN ALPHA-PS2 cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;integrin binding#GO:0005178;binding#GO:0005488;signaling receptor binding#GO:0005102 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cell adhesion mediated by integrin#GO:0033627;cell-cell adhesion#GO:0098609;cell communication#GO:0007154;cell adhesion#GO:0007155;cell-substrate adhesion#GO:0031589;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cell-matrix adhesion#GO:0007160;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;integrin-mediated signaling pathway#GO:0007229;biological regulation#GO:0065007;signaling#GO:0023052 receptor complex#GO:0043235;membrane protein complex#GO:0098796;external side of plasma membrane#GO:0009897;cell surface#GO:0009986;protein-containing complex#GO:0032991;plasma membrane signaling receptor complex#GO:0098802;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 cell adhesion molecule#PC00069;integrin#PC00126 Integrin signalling pathway#P00034>Integrin alpha#P00941 CIOIN|Ensembl=ENSCING00000016077.2|UniProtKB=F6W5C2 F6W5C2 PTHR46500:SF1 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 221 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 221 organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cell projection organization#GO:0030030;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection assembly#GO:0120031;motile cilium assembly#GO:0044458;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031 motile cilium#GO:0031514;9+2 motile cilium#GO:0097729;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;cilium#GO:0005929;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025 structural protein#PC00211 CIOIN|Ensembl=ENSCING00000019695.1|UniProtKB=H2XKA5 H2XKA5 PTHR19282:SF534 TETRASPANIN TETRASPANIN FAMILY-RELATED cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000001434.3|UniProtKB=F6W7H5 F6W7H5 PTHR12775:SF0 PROTEIN C20ORF43 HOMOLOG REPLICATION TERMINATION FACTOR 2 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;DNA-templated DNA replication#GO:0006261;DNA replication#GO:0006260;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000020435.1|UniProtKB=H2Y3R7 H2Y3R7 PTHR13663:SF2 SIMILAR TO RIKEN CDNA 6430548M08 SIMILAR TO RIKEN CDNA 6430548M08 CIOIN|Ensembl=ENSCING00000015067.2|UniProtKB=F6S7P1 F6S7P1 PTHR32261:SF1 CALCIUM HOMEOSTASIS MODULATOR PROTEIN CALCIUM HOMEOSTASIS MODULATOR PROTEIN monoatomic cation channel activity#GO:0005261;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;transporter activity#GO:0005215 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 transporter#PC00227;voltage-gated ion channel#PC00241 CIOIN|Ensembl=ENSCING00000024672.1|UniProtKB=H2Y3F6 H2Y3F6 PTHR13465:SF2 UPF0183 PROTEIN PHAGOSOME ASSEMBLY FACTOR 1 CIOIN|Ensembl=ENSCING00000000963.3|UniProtKB=F7BAC4 F7BAC4 PTHR14379:SF79 LIMKAIN B LKAP MEIOSIS ARREST FEMALE PROTEIN 1 HOMOLOG-LIKE PROTEIN protein-containing complex binding#GO:0044877;binding#GO:0005488 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000010773.3|UniProtKB=F6ZDJ9 F6ZDJ9 LOC100178172 PTHR34256:SF1 UPF0561 PROTEIN C2ORF68 UPF0561 PROTEIN C2ORF68 CIOIN|Ensembl=ENSCING00000021620.1|UniProtKB=F6VTQ0 F6VTQ0 PTHR20765:SF1 SOLUTE CARRIER FAMILY 43 MEMBER 3-RELATED EQUILIBRATIVE NUCLEOBASE TRANSPORTER 1 amino acid transporter#PC00046;secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000015950.2|UniProtKB=F6X4L2 F6X4L2 LOC100187041 PTHR23320:SF165 MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MS4A -RELATED MARVEL DOMAIN-CONTAINING PROTEIN transporter#PC00227 CIOIN|Ensembl=ENSCING00000016138.2|UniProtKB=F6TG38 F6TG38 PTHR35170:SF2 PROTEIN DD3-3 PROTEIN DD3-3 CIOIN|Ensembl=ENSCING00000015372.2|UniProtKB=F7A5L4 F7A5L4 PTHR12710:SF0 NUCLEAR PROTEIN LOCALIZATION 4 NUCLEAR PROTEIN LOCALIZATION PROTEIN 4 HOMOLOG enzyme binding#GO:0019899;protein binding#GO:0005515;ubiquitin-like protein binding#GO:0032182;ubiquitin protein ligase binding#GO:0031625;binding#GO:0005488;ubiquitin-like protein ligase binding#GO:0044389;ubiquitin binding#GO:0043130 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000007514.3|UniProtKB=F6UJM5 F6UJM5 LOC100183722 PTHR22734:SF3 U3 SMALL NUCLEOLAR RIBONUCLEOPROTEIN PROTEIN IMP4 RIBOSOME PRODUCTION FACTOR 1 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;ribosomal large subunit biogenesis#GO:0042273;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;maturation of 5.8S rRNA#GO:0000460;maturation of LSU-rRNA#GO:0000470;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;preribosome, large subunit precursor#GO:0030687;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;nuclear lumen#GO:0031981 RNA splicing factor#PC00148;RNA processing factor#PC00147;RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000005921.3|UniProtKB=F6YYG7 F6YYG7 LOC100176441 PTHR11773:SF1 GLYCINE DEHYDROGENASE, DECARBOXYLATING GLYCINE DEHYDROGENASE (DECARBOXYLATING), MITOCHONDRIAL cation binding#GO:0043169;amino acid binding#GO:0016597;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;carboxylic acid binding#GO:0031406;heterocyclic compound binding#GO:1901363;organic acid binding#GO:0043177;ion binding#GO:0043167;anion binding#GO:0043168;oxidoreductase activity#GO:0016491 oxoacid metabolic process#GO:0043436;proteinogenic amino acid metabolic process#GO:0170039;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;amino acid catabolic process#GO:0009063;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;nitrogen compound metabolic process#GO:0006807;alpha-amino acid metabolic process#GO:1901605;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;L-amino acid metabolic process#GO:0170033;carboxylic acid metabolic process#GO:0019752;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;oxidoreductase complex#GO:1990204;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622 dehydrogenase#PC00092;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000013652.2|UniProtKB=F6UBE7 F6UBE7 LOC101242476 PTHR10334:SF590 CYSTEINE-RICH SECRETORY PROTEIN-RELATED SCP DOMAIN-CONTAINING PROTEIN extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 defense/immunity protein#PC00090 CIOIN|Ensembl=ENSCING00000006013.3|UniProtKB=F6SFQ0 F6SFQ0 PTHR10694:SF33 LYSINE-SPECIFIC DEMETHYLASE LYSINE-SPECIFIC DEMETHYLASE 5 histone modifying activity#GO:0140993;demethylase activity#GO:0032451;catalytic activity, acting on a protein#GO:0140096;histone demethylase activity#GO:0032452;catalytic activity#GO:0003824 protein-DNA complex organization#GO:0071824;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biosynthetic process#GO:0009889;protein-containing complex organization#GO:0043933;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;chromatin remodeling#GO:0006338;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077;histone modifying enzyme#PC00261 CIOIN|Ensembl=ENSCING00000023206.1|UniProtKB=H2Y2X3 H2Y2X3 LOC100187093 PTHR10697:SF1 MAMMALIAN EPENDYMIN-RELATED PROTEIN 1 MAMMALIAN EPENDYMIN-RELATED PROTEIN 1 cytoplasm#GO:0005737;lysosome#GO:0005764;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;lytic vacuole#GO:0000323;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000025215.1|UniProtKB=Q8HIN1 Q8HIN1 NADH3 PTHR11058:SF9 NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 3 NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 3 transmembrane transporter activity#GO:0022857;primary active transmembrane transporter activity#GO:0015399;electron transfer activity#GO:0009055;catalytic activity#GO:0003824;oxidoreductase activity, acting on NAD(P)H#GO:0016651;NADH dehydrogenase activity#GO:0003954;active transmembrane transporter activity#GO:0022804;oxidoreductase activity#GO:0016491;transporter activity#GO:0005215 oxidoreductase complex#GO:1990204;membrane protein complex#GO:0098796;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;membrane#GO:0016020;NADH dehydrogenase complex#GO:0030964;catalytic complex#GO:1902494 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000007672.3|UniProtKB=F6T7B1 F6T7B1 PTHR12428:SF66 OXA1 MITOCHONDRIAL INNER MEMBRANE PROTEIN OXA1L localization within membrane#GO:0051668;cellular localization#GO:0051641;macromolecule localization#GO:0033036;membrane organization#GO:0061024;protein localization to membrane#GO:0072657;establishment of protein localization to organelle#GO:0072594;cellular component organization#GO:0016043;protein localization to mitochondrion#GO:0070585;cellular process#GO:0009987;establishment of protein localization#GO:0045184;inner mitochondrial membrane organization#GO:0007007;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of protein localization to membrane#GO:0090150;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;establishment of protein localization to mitochondrion#GO:0072655;organelle organization#GO:0006996;establishment of localization in cell#GO:0051649;protein localization to organelle#GO:0033365;mitochondrion organization#GO:0007005;mitochondrial membrane organization#GO:0007006;protein insertion into membrane#GO:0051205 envelope#GO:0031975;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;organelle membrane#GO:0031090;organelle inner membrane#GO:0019866;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227 transporter#PC00227 CIOIN|Ensembl=ENSCING00000012767.1|UniProtKB=F6ZQ58 F6ZQ58 LOC104266855 PTHR12709:SF1 DNA-DIRECTED RNA POLYMERASE II, III DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC8 cellular aromatic compound metabolic process#GO:0006725;DNA-templated transcription#GO:0006351;heterocycle metabolic process#GO:0046483;transcription by RNA polymerase III#GO:0006383;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;RNA biosynthetic process#GO:0032774;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;DNA-templated transcription initiation#GO:0006352;aromatic compound biosynthetic process#GO:0019438;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;DNA-directed RNA polymerase complex#GO:0000428;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;RNA polymerase III complex#GO:0005666;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 RNA metabolism protein#PC00031;DNA-directed RNA polymerase#PC00019 CIOIN|Ensembl=ENSCING00000006970.3|UniProtKB=F6SYX7 F6SYX7 PTHR11475:SF58 OXIDASE/PEROXIDASE PEROXIDASIN oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;antioxidant activity#GO:0016209;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 peroxidase#PC00180;metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000015250.2|UniProtKB=F6ULJ5 F6ULJ5 PTHR24412:SF497 KELCH PROTEIN KELCH-LIKE PROTEIN 18 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000019997.1|UniProtKB=H2XRM1 H2XRM1 PTHR12270:SF25 GLYCOSYLTRANSFERASE-RELATED GLYCOSYLTRANSFERASE-LIKE PROTEIN LARGE glucuronosyltransferase activity#GO:0015020;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194;pentosyltransferase activity#GO:0016763;xylosyltransferase activity#GO:0042285;hexosyltransferase activity#GO:0016758 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;protein O-linked glycosylation#GO:0006493;protein O-linked mannosylation#GO:0035269;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;protein mannosylation#GO:0035268;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085;mannosylation#GO:0097502 glycosyltransferase#PC00111 CIOIN|Ensembl=ENSCING00000013912.2|UniProtKB=A0A1W5BGB6 A0A1W5BGB6 LOC100185985 PTHR15597:SF22 ATAXIN 2-BINDING PROTEIN 1-RELATED RNA-BINDING FOX PROTEIN 1, ISOFORM H nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 regulation of nitrogen compound metabolic process#GO:0051171;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of mRNA processing#GO:0050684;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of metabolic process#GO:0019222;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;regulation of cellular metabolic process#GO:0031323;regulation of mRNA metabolic process#GO:1903311 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA splicing factor#PC00148;RNA processing factor#PC00147;RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000001259.3|UniProtKB=F7AE92 F7AE92 PTHR43969:SF9 GLUTATHIONE S TRANSFERASE D10, ISOFORM A-RELATED GLUTATHIONE S TRANSFERASE D10, ISOFORM A-RELATED glutathione transferase activity#GO:0004364;transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824 sulfur compound metabolic process#GO:0006790;nitrogen compound metabolic process#GO:0006807;peptide metabolic process#GO:0006518;cellular modified amino acid metabolic process#GO:0006575;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular process#GO:0009987;glutathione metabolic process#GO:0006749;amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000004317.3|UniProtKB=F6SH45 F6SH45 LOC100182536 PTHR24240:SF223 OPSIN MELATONIN RECEPTOR 1B signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 signal transduction#GO:0007165;response to light stimulus#GO:0009416;cellular response to stimulus#GO:0051716;detection of stimulus#GO:0051606;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;regulation of cellular process#GO:0050794;response to radiation#GO:0009314;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;response to abiotic stimulus#GO:0009628;signaling#GO:0023052;cellular response to light stimulus#GO:0071482 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 CIOIN|Ensembl=ENSCING00000001716.3|UniProtKB=F6TVX8 F6TVX8 LOC100185344 PTHR23503:SF8 SOLUTE CARRIER FAMILY 2 FACILITATED GLUCOSE TRANSPORTER PROTEIN 1 transmembrane transporter activity#GO:0022857;sugar transmembrane transporter activity#GO:0051119;transporter activity#GO:0005215;carbohydrate transmembrane transporter activity#GO:0015144 localization#GO:0051179;organic substance transport#GO:0071702;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810;cellular process#GO:0009987;carbohydrate transmembrane transport#GO:0034219;carbohydrate transport#GO:0008643 cellular anatomical entity#GO:0110165;membrane#GO:0016020 secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000008346.3|UniProtKB=F7B426 F7B426 LOC100185581 PTHR24044:SF417 NOTCH LIGAND FAMILY MEMBER WEARY, ISOFORM B protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 intercellular signal molecule#PC00207 CIOIN|Ensembl=ENSCING00000005419.3|UniProtKB=F6YQR4 F6YQR4 PTHR12687:SF4 NUCLEOLAR COMPLEX 2 AND RAD4-RELATED NUCLEOLAR COMPLEX PROTEIN 2 HOMOLOG cellular component organization or biogenesis#GO:0071840;cellular component biogenesis#GO:0044085;ribosome biogenesis#GO:0042254;cellular process#GO:0009987;ribosomal large subunit biogenesis#GO:0042273;ribonucleoprotein complex biogenesis#GO:0022613 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;preribosome, large subunit precursor#GO:0030687;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513;90S preribosome#GO:0030686 CIOIN|Ensembl=ENSCING00000001732.3|UniProtKB=F7AMV0 F7AMV0 LOC100186420 PTHR45973:SF12 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT SDS22-RELATED DYNEIN REGULATORY COMPLEX SUBUNIT 3 membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;cilium#GO:0005929;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025 phosphatase modulator#PC00184 CIOIN|Ensembl=ENSCING00000024044.1|UniProtKB=H2XXG2 H2XXG2 PTHR23282:SF142 APICAL ENDOSOMAL GLYCOPROTEIN PRECURSOR. MAM DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000024568.1|UniProtKB=H2XXP3 H2XXP3 PTHR23055:SF178 CALCIUM BINDING PROTEINS NEUROCALCIN HOMOLOG cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488 calmodulin-related#PC00061 CIOIN|Ensembl=ENSCING00000019287.1|UniProtKB=H2Y3J4 H2Y3J4 PTHR22749:SF6 RIBOFLAVIN KINASE/FMN ADENYLYLTRANSFERASE RIBOFLAVIN KINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301 cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;nucleoside monophosphate metabolic process#GO:0009123;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;ribonucleoside monophosphate metabolic process#GO:0009161;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 Flavin biosynthesis#P02741>Riboflavin kinase#P02934;Flavin biosynthesis#P02741>FAD synthetase#P02936 CIOIN|Ensembl=ENSCING00000015812.2|UniProtKB=F6RW25 F6RW25 PTHR46780:SF9 PROTEIN EVA-1 D-GALACTOSIDE_L-RHAMNOSE BINDING SUEL LECTIN PROTEIN CIOIN|Ensembl=ENSCING00000024142.1|UniProtKB=H2XSG7 H2XSG7 PTHR24038:SF11 STABILIN INTEGRIN BETA-LIKE PROTEIN E membrane trafficking regulatory protein#PC00151 CIOIN|Ensembl=ENSCING00000022188.1|UniProtKB=H2XLH4 H2XLH4 PTHR10390:SF61 HOMEOBOX PROTEIN SIX HOMEOBOX PROTEIN SIX2 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 CIOIN|Ensembl=ENSCING00000006395.3|UniProtKB=F6RJT7 F6RJT7 PTHR11909:SF422 CASEIN KINASE-RELATED BCDNA.LD23371-RELATED transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular process#GO:0009987;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 CIOIN|Ensembl=ENSCING00000020797.1|UniProtKB=H2Y3D5 H2Y3D5 PTHR10890:SF27 CYSTEINYL-TRNA SYNTHETASE CYSTEINE--TRNA LIGASE, MITOCHONDRIAL-RELATED catalytic activity, acting on RNA#GO:0140098;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;ligase activity#GO:0016874;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;catalytic activity, acting on a nucleic acid#GO:0140640;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;anion binding#GO:0043168;ATP binding#GO:0005524 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;peptide biosynthetic process#GO:0043043;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 aminoacyl-tRNA synthetase#PC00047;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000000130.3|UniProtKB=F7A0P7 F7A0P7 LOC100175426 PTHR22974:SF23 MIXED LINEAGE PROTEIN KINASE TOUSLED-LIKE KINASE, ISOFORM G transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cell cycle process#GO:0022402;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular process#GO:0009987;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;chromosome segregation#GO:0007059;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell cycle#GO:0007049;peptidyl-serine modification#GO:0018209;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000006376.3|UniProtKB=F6RL82 F6RL82 PTHR13173:SF10 WW DOMAIN BINDING PROTEIN 4 WW DOMAIN-BINDING PROTEIN 4 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;precatalytic spliceosome#GO:0071011;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000002438.3|UniProtKB=F6QBZ6 F6QBZ6 LOC100181621 PTHR24251:SF30 OVOCHYMASE-RELATED MEMBRANE FRIZZLED-RELATED PROTEIN serine protease#PC00203;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000009459.3|UniProtKB=F7AY44 F7AY44 PTHR45615:SF50 MYOSIN HEAVY CHAIN, NON-MUSCLE MYOSIN-16 microfilament motor activity#GO:0000146;cytoskeletal protein binding#GO:0008092;ATP-dependent activity#GO:0140657;binding#GO:0005488;actin filament binding#GO:0051015;cytoskeletal motor activity#GO:0003774;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779 supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;supramolecular fiber#GO:0099512;supramolecular polymer#GO:0099081;myosin complex#GO:0016459;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 CIOIN|Ensembl=ENSCING00000024280.1|UniProtKB=H2XZ37 H2XZ37 PTHR34400:SF4 FAMILY NOT NAMED MEMBRANE PROTEIN CIOIN|Ensembl=ENSCING00000011630.2|UniProtKB=F7APT3 F7APT3 PTHR46126:SF1 DYNACTIN SUBUNIT 5 DYNACTIN SUBUNIT 5 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 CIOIN|Ensembl=ENSCING00000022675.1|UniProtKB=H2Y0Z7 H2Y0Z7 PTHR24302:SF15 CYTOCHROME P450 FAMILY 3 FATTY-ACID PEROXYGENASE oxygenase#PC00177;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000006699.3|UniProtKB=F7ARU9 F7ARU9 LOC100178581 PTHR14002:SF54 ENDOGLIN/TGF-BETA RECEPTOR TYPE III ZONA PELLUCIDA SPERM-BINDING PROTEIN 2 transmembrane signal receptor#PC00197 CIOIN|Ensembl=ENSCING00000016779.2|UniProtKB=F6QTS6 F6QTS6 LOC100175914 PTHR10632:SF2 SULFIDE:QUINONE OXIDOREDUCTASE SULFIDE:QUINONE OXIDOREDUCTASE, MITOCHONDRIAL nucleotide binding#GO:0000166;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;flavin adenine dinucleotide binding#GO:0050660;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167;oxidoreductase activity#GO:0016491 cellular metabolic process#GO:0044237;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987;metabolic process#GO:0008152 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000001748.3|UniProtKB=F7AMF2 F7AMF2 PTHR47572:SF4 LIPOPROTEIN-RELATED LACTONASE DRP35 CIOIN|Ensembl=ENSCING00000000632.3|UniProtKB=F6RRB9 F6RRB9 LOC100181739 PTHR36978:SF4 P-LOOP CONTAINING NUCLEOTIDE TRIPHOSPHATE HYDROLASE P-LOOP CONTAINING NUCLEOSIDE TRIPHOSPHATE HYDROLASE PROTEIN metabolite interconversion enzyme#PC00262;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000000622.3|UniProtKB=F6RRQ4 F6RRQ4 LOC100186343 PTHR22776:SF97 MARVEL-CONTAINING POTENTIAL LIPID RAFT-ASSOCIATED PROTEIN RE01453P cellular anatomical entity#GO:0110165;membrane#GO:0016020 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000005895.3|UniProtKB=F6SHZ7 F6SHZ7 capzb PTHR10619:SF0 F-ACTIN-CAPPING PROTEIN SUBUNIT BETA F-ACTIN-CAPPING PROTEIN SUBUNIT BETA ISOFORMS 1 AND 2 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 negative regulation of protein polymerization#GO:0032272;negative regulation of protein depolymerization#GO:1901880;negative regulation of biological process#GO:0048519;negative regulation of actin filament depolymerization#GO:0030835;developmental process#GO:0032502;regulation of cellular component organization#GO:0051128;regulation of actin polymerization or depolymerization#GO:0008064;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;regulation of protein-containing complex assembly#GO:0043254;regulation of biological quality#GO:0065008;anatomical structure morphogenesis#GO:0009653;regulation of cellular component biogenesis#GO:0044087;negative regulation of organelle organization#GO:0010639;negative regulation of protein-containing complex disassembly#GO:0043242;regulation of actin cytoskeleton organization#GO:0032956;barbed-end actin filament capping#GO:0051016;regulation of actin filament-based process#GO:0032970;negative regulation of cellular component organization#GO:0051129;regulation of protein polymerization#GO:0032271;negative regulation of cellular process#GO:0048523;regulation of anatomical structure size#GO:0090066;regulation of actin filament length#GO:0030832;regulation of organelle organization#GO:0033043;regulation of actin filament organization#GO:0110053;regulation of protein-containing complex disassembly#GO:0043244;cellular component organization#GO:0016043;cell morphogenesis#GO:0000902;cellular process#GO:0009987;regulation of actin filament polymerization#GO:0030833;regulation of cellular component size#GO:0032535;negative regulation of supramolecular fiber organization#GO:1902904;regulation of supramolecular fiber organization#GO:1902903;cellular component organization or biogenesis#GO:0071840;regulation of protein depolymerization#GO:1901879;regulation of actin filament depolymerization#GO:0030834;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;negative regulation of actin filament polymerization#GO:0030837;biological regulation#GO:0065007;negative regulation of protein-containing complex assembly#GO:0031333;negative regulation of cytoskeleton organization#GO:0051494 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-motor actin binding protein#PC00165 CIOIN|Ensembl=ENSCING00000003958.3|UniProtKB=F6Z2I4 F6Z2I4 PTHR16228:SF7 DIVALENT CATION TRANSPORTER SOLUTE CARRIER FAMILY 41 SLC41A_MGTE INTEGRAL MEMBRANE DOMAIN-CONTAINING PROTEIN secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000016664.2|UniProtKB=F6PJG3 F6PJG3 LOC100182074 PTHR24034:SF209 EGF-LIKE DOMAIN-CONTAINING PROTEIN EGF-LIKE DOMAIN-CONTAINING PROTEIN extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 CIOIN|Ensembl=ENSCING00000019728.1|UniProtKB=H2XNN0 H2XNN0 PTHR11003:SF330 POTASSIUM CHANNEL, SUBFAMILY K POTASSIUM CHANNEL DOMAIN-CONTAINING PROTEIN monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated potassium channel activity#GO:0005249;channel activity#GO:0015267;transporter activity#GO:0005215;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;regulation of membrane potential#GO:0042391;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;localization#GO:0051179;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;monoatomic cation transport#GO:0006812;potassium ion transmembrane transport#GO:0071805;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;potassium ion transport#GO:0006813 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 CIOIN|Ensembl=ENSCING00000002733.3|UniProtKB=F6TPM4 F6TPM4 PTHR14614:SF130 HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN PROTEIN-LYSINE N-METHYLTRANSFERASE EEF2KMT protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000023485.1|UniProtKB=H2XNQ4 H2XNQ4 PTHR11486:SF148 FIBROBLAST GROWTH FACTOR PROTEIN LET-756 molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;binding#GO:0005488;growth factor activity#GO:0008083;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;growth factor receptor binding#GO:0070851;protein binding#GO:0005515;signaling receptor binding#GO:0005102;fibroblast growth factor receptor binding#GO:0005104 positive regulation of gene expression#GO:0010628;regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;positive regulation of cell population proliferation#GO:0008284;positive regulation of protein modification process#GO:0031401;regulation of intracellular signal transduction#GO:1902531;response to fibroblast growth factor#GO:0071774;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;regulation of cell migration#GO:0030334;anatomical structure morphogenesis#GO:0009653;regulation of signal transduction#GO:0009966;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;cellular developmental process#GO:0048869;cellular response to endogenous stimulus#GO:0071495;positive regulation of phosphorus metabolic process#GO:0010562;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;positive regulation of cell communication#GO:0010647;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;fibroblast growth factor receptor signaling pathway#GO:0008543;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;regulation of locomotion#GO:0040012;response to growth factor#GO:0070848;animal organ development#GO:0048513;regulation of signaling#GO:0023051;developmental process#GO:0032502;positive regulation of MAPK cascade#GO:0043410;positive regulation of response to stimulus#GO:0048584;positive regulation of biosynthetic process#GO:0009891;cell differentiation#GO:0030154;response to endogenous stimulus#GO:0009719;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of intracellular signal transduction#GO:1902533;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;signaling#GO:0023052;regulation of cell communication#GO:0010646;positive regulation of protein phosphorylation#GO:0001934;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;regulation of cell population proliferation#GO:0042127;regulation of cell motility#GO:2000145;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;cellular response to growth factor stimulus#GO:0071363;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;animal organ morphogenesis#GO:0009887;cellular response to fibroblast growth factor stimulus#GO:0044344 cytoplasm#GO:0005737;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576;intracellular anatomical structure#GO:0005622 intercellular signal molecule#PC00207;growth factor#PC00112 CIOIN|Ensembl=ENSCING00000008978.3|UniProtKB=F6PKW3 F6PKW3 PTHR24418:SF418 TYROSINE-PROTEIN KINASE TYROSINE-PROTEIN KINASE FER protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 non-receptor tyrosine protein kinase#PC00168 CIOIN|Ensembl=ENSCING00000017358.2|UniProtKB=A0A1W5BL25 A0A1W5BL25 LOC100182160 PTHR31120:SF6 METALLOPROTEASE TIKI METALLOPROTEASE TIKI HOMOLOG hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular anatomical entity#GO:0110165;membrane#GO:0016020 metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000003953.3|UniProtKB=F6WJQ9 F6WJQ9 LOC100179182 PTHR43999:SF1 DNAJ HOMOLOG SUBFAMILY C MEMBER 2 DNAJ HOMOLOG SUBFAMILY C MEMBER 2 binding#GO:0005488;ribosome binding#GO:0043022;ribonucleoprotein complex binding#GO:0043021;heat shock protein binding#GO:0031072;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;protein-folding chaperone binding#GO:0051087;Hsp70 protein binding#GO:0030544 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein folding#GO:0006457;'de novo' protein folding#GO:0006458;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 chaperone#PC00072 CIOIN|Ensembl=ENSCING00000006578.3|UniProtKB=F6R1D9 F6R1D9 LOC100179203 PTHR42901:SF1 ALCOHOL DEHYDROGENASE ALCOHOL DEHYDROGENASE dehydrogenase#PC00092;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000003238.3|UniProtKB=F6ZNU2 F6ZNU2 LOC100183502 PTHR35155:SF1 SPERMATOGENESIS-ASSOCIATED PROTEIN 24 SPERMATOGENESIS-ASSOCIATED PROTEIN 24 nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000007915.3|UniProtKB=F7AAC8 F7AAC8 LOC100186095 PTHR14905:SF21 NG37 VWFA DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000005184.3|UniProtKB=F6RXD4 F6RXD4 LOC100179112 PTHR45624:SF12 MITOCHONDRIAL BASIC AMINO ACIDS TRANSPORTER-RELATED MITOCHONDRIAL ORNITHINE TRANSPORTER 1 L-amino acid transmembrane transporter activity#GO:0015179;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;amino acid transmembrane transporter activity#GO:0015171;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215;organic acid transmembrane transporter activity#GO:0005342 L-amino acid transport#GO:0015807;transmembrane transport#GO:0055085;amino acid transport#GO:0006865;organic anion transport#GO:0015711;organic acid transport#GO:0015849;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942;cellular process#GO:0009987;carboxylic acid transmembrane transport#GO:1905039;mitochondrial transport#GO:0006839;localization#GO:0051179;organic substance transport#GO:0071702;amino acid transmembrane transport#GO:0003333;establishment of localization#GO:0051234;L-alpha-amino acid transmembrane transport#GO:1902475;organic acid transmembrane transport#GO:1903825;mitochondrial transmembrane transport#GO:1990542 transporter#PC00227 CIOIN|Ensembl=ENSCING00000004481.3|UniProtKB=F6TEZ1 F6TEZ1 LOC100182145 PTHR10709:SF2 ACTIN-RELATED PROTEIN 2/3 COMPLEX SUBUNIT 1 ACTIN-RELATED PROTEIN 2_3 COMPLEX SUBUNIT cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;Arp2/3 complex-mediated actin nucleation#GO:0034314;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;Arp2/3 protein complex#GO:0005885;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 Integrin signalling pathway#P00034>Arp2/3#P00912;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Arp2/3#P00876;Cytoskeletal regulation by Rho GTPase#P00016>ARP2/3#P00511;Huntington disease#P00029>Arp2/3 complex#P00811 CIOIN|Ensembl=ENSCING00000021025.1|UniProtKB=H2Y252 H2Y252 PTHR11783:SF43 SULFOTRANSFERASE SULT AMINE SULFOTRANSFERASE-RELATED sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824 cellular metabolic process#GO:0044237;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000001945.3|UniProtKB=F6XU15 F6XU15 PTHR13872:SF1 DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT STT3B glycosyltransferase#PC00111 CIOIN|Ensembl=ENSCING00000014273.2|UniProtKB=F6XA49 F6XA49 LOC100185445 PTHR10504:SF131 BACTERICIDAL PERMEABILITY-INCREASING BPI PROTEIN-RELATED BPI2 DOMAIN-CONTAINING PROTEIN defense/immunity protein#PC00090 CIOIN|Ensembl=ENSCING00000020544.1|UniProtKB=H2XZ40 H2XZ40 PTHR11188:SF176 ARRESTIN DOMAIN CONTAINING PROTEIN ARRESTIN DOMAIN-CONTAINING PROTEIN 1 localization#GO:0051179;organic substance transport#GO:0071702;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;transport#GO:0006810;protein transport#GO:0015031;nitrogen compound transport#GO:0071705;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000003029.3|UniProtKB=F6QAF5 F6QAF5 LOC100185184 PTHR12352:SF3 SECRETED MODULAR CALCIUM-BINDING PROTEIN NIDOGEN-2 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 calmodulin-related#PC00061 CIOIN|Ensembl=ENSCING00000000433.3|UniProtKB=F6ZS66 F6ZS66 PTHR10457:SF7 MEVALONATE KINASE/GALACTOKINASE GALACTOKINASE-RELATED transferase activity, transferring phosphorus-containing groups#GO:0016772;carbohydrate kinase activity#GO:0019200;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301 monosaccharide metabolic process#GO:0005996;hexose metabolic process#GO:0019318;carbohydrate metabolic process#GO:0005975;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;primary metabolic process#GO:0044238;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;carbohydrate kinase#PC00065 Fructose galactose metabolism#P02744>Galactokinase#P02960 CIOIN|Ensembl=ENSCING00000023447.1|UniProtKB=H2XNI1 H2XNI1 PTHR22589:SF103 CARNITINE O-ACYLTRANSFERASE CARNITINE O-ACETYL-TRANSFERASE, ISOFORM A-RELATED transferase#PC00220;acyltransferase#PC00042;metabolite interconversion enzyme#PC00262 Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>CAT#P01076;Nicotinic acetylcholine receptor signaling pathway#P00044>CAT#P01087;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>CAT#P01063 CIOIN|Ensembl=ENSCING00000020568.1|UniProtKB=H2XSM6 H2XSM6 LOC100183830 PTHR31475:SF5 UPF0462 PROTEIN UPF0462 PROTEIN C4ORF33 HOMOLOG CIOIN|Ensembl=ENSCING00000002227.3|UniProtKB=F6X3K4 F6X3K4 LOC100175175 PTHR11913:SF12 COFILIN-RELATED COFILIN_ACTIN-DEPOLYMERIZING FACTOR HOMOLOG-RELATED cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 cellular component organization or biogenesis#GO:0071840;cellular component disassembly#GO:0022411;actin filament-based process#GO:0030029;protein-containing complex disassembly#GO:0032984;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;actin polymerization or depolymerization#GO:0008154;cellular component organization#GO:0016043;protein depolymerization#GO:0051261;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987;actin filament depolymerization#GO:0030042 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165 Cytoskeletal regulation by Rho GTPase#P00016>Cofilin#P00508 CIOIN|Ensembl=ENSCING00000003446.3|UniProtKB=F6YAG6 F6YAG6 PTHR23176:SF129 RHO/RAC/CDC GTPASE-ACTIVATING PROTEIN RHO GTPASE ACTIVATING PROTEIN AT 16F, ISOFORM E-RELATED biological regulation#GO:0065007;regulation of hydrolase activity#GO:0051336;regulation of catalytic activity#GO:0050790;regulation of molecular function#GO:0065009;regulation of GTPase activity#GO:0043087 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 G-protein modulator#PC00022;protein-binding activity modulator#PC00095;GTPase-activating protein#PC00257 PDGF signaling pathway#P00047>Rho#P01174 CIOIN|Ensembl=ENSCING00000000771.3|UniProtKB=F6PHA1 F6PHA1 LOC100179141 PTHR34153:SF2 SI:CH211-262H13.3-RELATED-RELATED SI:CH211-262H13.3-RELATED CIOIN|Ensembl=ENSCING00000012331.2|UniProtKB=F7ABQ9 F7ABQ9 PTHR24372:SF77 GLYCOPROTEIN HORMONE RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 response to organic substance#GO:0010033;positive regulation of adenylate cyclase activity#GO:0045762;regulation of lyase activity#GO:0051339;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;cellular response to stimulus#GO:0051716;regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;cellular response to endogenous stimulus#GO:0071495;cellular response to chemical stimulus#GO:0070887;positive regulation of catalytic activity#GO:0043085;cellular response to organic substance#GO:0071310;regulation of cyclase activity#GO:0031279;positive regulation of molecular function#GO:0044093;cell communication#GO:0007154;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;positive regulation of cyclase activity#GO:0031281;hormone-mediated signaling pathway#GO:0009755;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to endogenous stimulus#GO:0009719;response to hormone#GO:0009725;cellular response to hormone stimulus#GO:0032870;response to chemical#GO:0042221;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of lyase activity#GO:0051349;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 CIOIN|Ensembl=ENSCING00000010478.3|UniProtKB=F6Q9F4 F6Q9F4 LOC100176558 PTHR10983:SF16 1-ACYLGLYCEROL-3-PHOSPHATE ACYLTRANSFERASE-RELATED LYSOCARDIOLIPIN ACYLTRANSFERASE 1 acyltransferase#PC00042 CIOIN|Ensembl=ENSCING00000008364.3|UniProtKB=F7AJP1 F7AJP1 LOC100184965 PTHR11879:SF55 ASPARTATE AMINOTRANSFERASE GLUTAMATE OXALOACETATE TRANSAMINASE 1, ISOFORM B transaminase activity#GO:0008483;transferase activity#GO:0016740;catalytic activity#GO:0003824 transaminase#PC00216;transferase#PC00220;metabolite interconversion enzyme#PC00262 Asparagine and aspartate biosynthesis#P02730>Aspartate aminotransferase#P02854 CIOIN|Ensembl=ENSCING00000009515.3|UniProtKB=Q8T3S5 Q8T3S5 CK2A PTHR24054:SF0 CASEIN KINASE II SUBUNIT ALPHA CASEIN KINASE II SUBUNIT ALPHA transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;protein phosphorylation#GO:0006468;cellular process#GO:0009987;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;peptidyl-threonine phosphorylation#GO:0018107;regulation of cellular process#GO:0050794;nitrogen compound metabolic process#GO:0006807;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;regulation of cell cycle#GO:0051726;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;serine/threonine protein kinase complex#GO:1902554;cytosol#GO:0005829;protein kinase complex#GO:1902911;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227 Cadherin signaling pathway#P00012>Casein kinase II#P00462;Wnt signaling pathway#P00057>Casein Kinase 2#P01459;Parkinson disease#P00049>Casein kinase II#P01236 CIOIN|Ensembl=ENSCING00000001697.3|UniProtKB=F6UJQ0 F6UJQ0 LOC100181055 PTHR24229:SF109 NEUROPEPTIDES RECEPTOR SOMATOSTATIN RECEPTOR TYPE 2-LIKE neuropeptide binding#GO:0042923;signaling receptor activity#GO:0038023;binding#GO:0005488;peptide binding#GO:0042277;amide binding#GO:0033218;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;neuropeptide signaling pathway#GO:0007218;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;neuron projection#GO:0043005;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 CIOIN|Ensembl=ENSCING00000006224.3|UniProtKB=F6YBU7 F6YBU7 LOC100187398 PTHR21668:SF0 EIF-1A EUKARYOTIC TRANSLATION INITIATION FACTOR 4C nucleic acid binding#GO:0003676;translation regulator activity#GO:0045182;translation regulator activity, nucleic acid binding#GO:0090079;binding#GO:0005488;organic cyclic compound binding#GO:0097159;translation initiation factor activity#GO:0003743;translation factor activity, RNA binding#GO:0008135 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;translational initiation#GO:0006413;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 translation initiation factor#PC00224;translation factor#PC00223;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000025104.1|UniProtKB=H2XQB5 H2XQB5 PTHR22093:SF0 LEUKOCYTE RECEPTOR CLUSTER LRC MEMBER 1 LEUKOCYTE RECEPTOR CLUSTER MEMBER 1 CIOIN|Ensembl=ENSCING00000009191.3|UniProtKB=F6SD56 F6SD56 LOC100183540 PTHR23023:SF226 DIMETHYLANILINE MONOOXYGENASE FLAVIN-CONTAINING MONOOXYGENASE oxygenase#PC00177;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000000779.3|UniProtKB=F7A912 F7A912 PTHR21646:SF46 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE cysteine protease#PC00081;protease#PC00190 CIOIN|Ensembl=ENSCING00000007140.3|UniProtKB=F7BH38 F7BH38 PTHR13780:SF35 AMP-ACTIVATED PROTEIN KINASE, GAMMA REGULATORY SUBUNIT LD22662P kinase modulator#PC00140 CIOIN|Ensembl=ENSCING00000021617.1|UniProtKB=F6Z0V4 F6Z0V4 LOC113474404 PTHR15350:SF5 COP9 SIGNALOSOME COMPLEX SUBUNIT 7/DENDRITIC CELL PROTEIN GA17 COP9 SIGNALOSOME COMPLEX SUBUNIT 7 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;COP9 signalosome#GO:0008180;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000019263.1|UniProtKB=H2XPR5 H2XPR5 LOC100185807 PTHR10472:SF5 D-TYROSYL-TRNA TYR DEACYLASE D-AMINOACYL-TRNA DEACYLASE 1 catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity#GO:0016787;catalytic activity, acting on RNA#GO:0140098;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;tRNA metabolic process#GO:0006399;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 esterase#PC00097;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000005433.3|UniProtKB=F6UUV9 F6UUV9 LOC100182889 PTHR11774:SF6 GERANYLGERANYL TRANSFERASE TYPE BETA SUBUNIT PROTEIN FARNESYLTRANSFERASE SUBUNIT BETA prenyltransferase activity#GO:0004659;transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein modification process#GO:0036211;cellular process#GO:0009987;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;transferase complex#GO:1990234 acyltransferase#PC00042;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000023733.1|UniProtKB=F6ZW88 F6ZW88 LOC100183307 PTHR10671:SF108 EPITHELIAL MEMBRANE PROTEIN-RELATED CLAUDIN FAMILY PROTEIN-RELATED cytoskeletal protein#PC00085 CIOIN|Ensembl=ENSCING00000014757.2|UniProtKB=F6TQ79 F6TQ79 LOC100178079 PTHR14604:SF3 WD40 REPEAT PF20 SPERM-ASSOCIATED ANTIGEN 16 PROTEIN microtubule or microtubule-binding cytoskeletal protein#PC00157 CIOIN|Ensembl=ENSCING00000025058.1|UniProtKB=H2Y1F4 H2Y1F4 PTHR24240:SF223 OPSIN MELATONIN RECEPTOR 1B signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 signal transduction#GO:0007165;response to light stimulus#GO:0009416;cellular response to stimulus#GO:0051716;detection of stimulus#GO:0051606;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;regulation of cellular process#GO:0050794;response to radiation#GO:0009314;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;response to abiotic stimulus#GO:0009628;signaling#GO:0023052;cellular response to light stimulus#GO:0071482 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 CIOIN|Ensembl=ENSCING00000005067.3|UniProtKB=F6ZM55 F6ZM55 PTHR46542:SF1 X-BOX BINDING PROTEIN 1 X-BOX BINDING PROTEIN 1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000020099.1|UniProtKB=F6YQT3 F6YQT3 PTHR18866:SF33 CARBOXYLASE:PYRUVATE/ACETYL-COA/PROPIONYL-COA CARBOXYLASE METHYLCROTONOYL-COA CARBOXYLASE SUBUNIT ALPHA, MITOCHONDRIAL-RELATED ligase#PC00142 Methylmalonyl pathway#P02755>Propionyl-CoA carboxylase#P03033 CIOIN|Ensembl=ENSCING00000024266.1|UniProtKB=H2XQD5 H2XQD5 PTHR13693:SF3 CLASS II AMINOTRANSFERASE/8-AMINO-7-OXONONANOATE SYNTHASE LD36009P transaminase#PC00216;transferase#PC00220;metabolite interconversion enzyme#PC00262 Biotin biosynthesis#P02731>8-Amino-7-oxononanoate synthase#P02858 CIOIN|Ensembl=ENSCING00000019192.1|UniProtKB=H2XLM7 H2XLM7 PTHR28529:SF2 DNA REPAIR PROTEIN SWI5 HOMOLOG DNA REPAIR PROTEIN SWI5 HOMOLOG DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;double-strand break repair via homologous recombination#GO:0000724;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;response to stress#GO:0006950;nitrogen compound metabolic process#GO:0006807;recombinational repair#GO:0000725;cellular response to stress#GO:0033554;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 DNA metabolism protein#PC00009 CIOIN|Ensembl=ENSCING00000003062.3|UniProtKB=F6PLF9 F6PLF9 LOC100184076 PTHR10030:SF37 ALPHA-L-FUCOSIDASE ALPHA-L-FUCOSIDASE-RELATED hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 monosaccharide metabolic process#GO:0005996;carbohydrate derivative metabolic process#GO:1901135;glycosyl compound catabolic process#GO:1901658;carbohydrate derivative catabolic process#GO:1901136;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;hexose metabolic process#GO:0019318;glycosyl compound metabolic process#GO:1901657;carbohydrate metabolic process#GO:0005975;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;lysosome#GO:0005764;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;lytic vacuole#GO:0000323;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosidase#PC00110;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000016218.2|UniProtKB=F6ZRR5 F6ZRR5 PTHR24031:SF594 RNA HELICASE ATP-DEPENDENT RNA HELICASE DDX52-RELATED cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;maturation of SSU-rRNA#GO:0030490;ribosomal small subunit biogenesis#GO:0042274;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 ribonucleoprotein complex#GO:1990904;preribosome#GO:0030684;protein-containing complex#GO:0032991;90S preribosome#GO:0030686 RNA helicase#PC00032 CIOIN|Ensembl=ENSCING00000003312.3|UniProtKB=F6TBF9 F6TBF9 PTHR14212:SF0 U4/U6-ASSOCIATED RNA SPLICING FACTOR-RELATED U4_U6 SMALL NUCLEAR RIBONUCLEOPROTEIN PRP3 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704 ribonucleoprotein complex#GO:1990904;spliceosomal snRNP complex#GO:0097525;small nuclear ribonucleoprotein complex#GO:0030532;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;spliceosomal tri-snRNP complex#GO:0097526;U4/U6 x U5 tri-snRNP complex#GO:0046540;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA splicing factor#PC00148;RNA processing factor#PC00147;RNA metabolism protein#PC00031 mRNA splicing#P00058>U4#P01476;mRNA splicing#P00058>U6#P01473 CIOIN|Ensembl=ENSCING00000013547.2|UniProtKB=F6YCQ4 F6YCQ4 LOC100176306 PTHR21119:SF5 C2 DOMAIN-CONTAINING PROTEIN C2 DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000016942.2|UniProtKB=F6Z4I8 F6Z4I8 LOC100186942 PTHR14064:SF5 CHONDROMODULIN-RELATED LEUKOCYTE CELL-DERIVED CHEMOTAXIN 1 CIOIN|Ensembl=ENSCING00000009514.3|UniProtKB=F6XIZ4 F6XIZ4 LOC100175467 PTHR12458:SF8 ORF PROTEIN CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 20 regulation of microtubule-based process#GO:0032886;cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cell projection organization#GO:0030030;regulation of cell motility#GO:2000145;regulation of locomotion#GO:0040012;positive regulation of locomotion#GO:0040017;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;regulation of biological quality#GO:0065008;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;positive regulation of cell motility#GO:2000147;biological regulation#GO:0065007;plasma membrane bounded cell projection assembly#GO:0120031;positive regulation of biological process#GO:0048518 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;motile cilium#GO:0031514;microtubule organizing center#GO:0005815;microtubule cytoskeleton#GO:0015630;ciliary basal body#GO:0036064;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;cilium#GO:0005929;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 Transcription regulation by bZIP transcription factor#P00055>TFIIB#P01397;General transcription regulation#P00023>TFIIB#P00668 CIOIN|Ensembl=ENSCING00000002578.3|UniProtKB=A0A1W3JHR7 A0A1W3JHR7 LOC100185655 PTHR13869:SF24 MYELIN P0 RELATED BASEMENT MEMBRANE-SPECIFIC HEPARAN SULFATE PROTEOGLYCAN CORE PROTEIN-LIKE myelin protein#PC00161;structural protein#PC00211 CIOIN|Ensembl=ENSCING00000004910.3|UniProtKB=F7AQE7 F7AQE7 LOC100180404 PTHR18884:SF57 SEPTIN CELL DIVISION CONTROL PROTEIN 10 GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824 localization#GO:0051179;cell division#GO:0051301;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;cytoskeleton-dependent cytokinesis#GO:0061640;cell cycle process#GO:0022402;cell cycle#GO:0007049;cellular process#GO:0009987;cytokinesis#GO:0000910;protein localization#GO:0008104 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;cell division site#GO:0032153;cell cortex#GO:0005938;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085 CIOIN|Ensembl=ENSCING00000006488.3|UniProtKB=F6QWY0 F6QWY0 PTHR11929:SF145 ALPHA- 1,3 -FUCOSYLTRANSFERASE ALPHA-(1,3)-FUCOSYLTRANSFERASE FUT-1 transferase activity#GO:0016740;fucosyltransferase activity#GO:0008417;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 glycosylation#GO:0070085;metabolic process#GO:0008152 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000003276.3|UniProtKB=F6WNH9 F6WNH9 PTHR22599:SF8 MPS ONE BINDER KINASE ACTIVATOR-LIKE MOB MOB KINASE ACTIVATOR-LIKE 1 protein kinase activator activity#GO:0030295;protein kinase regulator activity#GO:0019887;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047;kinase regulator activity#GO:0019207;enzyme regulator activity#GO:0030234;kinase activator activity#GO:0019209 positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of protein modification process#GO:0031401;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;positive regulation of metabolic process#GO:0009893;positive regulation of biological process#GO:0048518;signaling#GO:0023052;positive regulation of protein phosphorylation#GO:0001934;positive regulation of phosphorylation#GO:0042327;cellular response to stimulus#GO:0051716;positive regulation of phosphorus metabolic process#GO:0010562;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;positive regulation of phosphate metabolic process#GO:0045937;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of protein phosphorylation#GO:0001932;biological regulation#GO:0065007;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 kinase modulator#PC00140;kinase activator#PC00138 CIOIN|Ensembl=ENSCING00000006936.3|UniProtKB=F6ZHF5 F6ZHF5 PTHR12027:SF112 WNT RELATED PROTEIN WNT-2 molecular function activator activity#GO:0140677;binding#GO:0005488;molecular function regulator activity#GO:0098772;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;cytokine activity#GO:0005125;G protein-coupled receptor binding#GO:0001664;signaling receptor binding#GO:0005102 cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;neurogenesis#GO:0022008;developmental process#GO:0032502;multicellular organism development#GO:0007275;cell communication#GO:0007154;cell fate commitment#GO:0045165;cell-cell signaling by wnt#GO:0198738;nervous system development#GO:0007399;cellular process#GO:0009987;regulation of biological process#GO:0050789;system development#GO:0048731;response to stimulus#GO:0050896;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;neuron differentiation#GO:0030182;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;cell-cell signaling#GO:0007267;signaling#GO:0023052;canonical Wnt signaling pathway#GO:0060070;Wnt signaling pathway#GO:0016055 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 intercellular signal molecule#PC00207 Wnt signaling pathway#P00057>Wnt#P01444;Alzheimer disease-presenilin pathway#P00004>Wnt#P00142;Angiogenesis#P00005>Wnt#P00206;Cadherin signaling pathway#P00012>Wnt#P00474 CIOIN|Ensembl=ENSCING00000005925.3|UniProtKB=F6WUF6 F6WUF6 LOC100180700 PTHR21148:SF11 THIOREDOXIN DOMAIN-CONTAINING PROTEIN 9 THIOREDOXIN DOMAIN-CONTAINING PROTEIN 9 microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cellular process#GO:0009987;microtubule-based process#GO:0007017;organelle organization#GO:0006996 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 protein-binding activity modulator#PC00095 CIOIN|Ensembl=ENSCING00000005287.3|UniProtKB=F6RUQ3 F6RUQ3 PTHR11599:SF11 PROTEASOME SUBUNIT ALPHA/BETA PROTEASOME SUBUNIT ALPHA TYPE-6 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;peptidase complex#GO:1905368;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;proteasome complex#GO:0000502;membrane-bounded organelle#GO:0043227;endopeptidase complex#GO:1905369;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protease#PC00190;protein modifying enzyme#PC00260 Parkinson disease#P00049>20S proteasome#P01227 CIOIN|Ensembl=ENSCING00000022805.1|UniProtKB=H2XQ43 H2XQ43 PTHR24240:SF223 OPSIN MELATONIN RECEPTOR 1B signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 signal transduction#GO:0007165;response to light stimulus#GO:0009416;cellular response to stimulus#GO:0051716;detection of stimulus#GO:0051606;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;regulation of cellular process#GO:0050794;response to radiation#GO:0009314;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;response to abiotic stimulus#GO:0009628;signaling#GO:0023052;cellular response to light stimulus#GO:0071482 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 CIOIN|Ensembl=ENSCING00000013225.2|UniProtKB=F6V4V8 F6V4V8 LOC100181451 PTHR21255:SF65 T-COMPLEX-ASSOCIATED-TESTIS-EXPRESSED 1/ DYNEIN LIGHT CHAIN TCTEX1 DOMAIN-CONTAINING PROTEIN 2 protein binding#GO:0005515;binding#GO:0005488 microtubule-based movement#GO:0007018;cellular process#GO:0009987;microtubule-based process#GO:0007017 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;microtubule cytoskeleton#GO:0015630;dynein complex#GO:0030286;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic dynein complex#GO:0005868;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;microtubule or microtubule-binding cytoskeletal protein#PC00157 CIOIN|Ensembl=ENSCING00000000550.3|UniProtKB=F6Q7A6 F6Q7A6 PTHR43570:SF16 ALDEHYDE DEHYDROGENASE ALDEHYDE DEHYDROGENASE TYPE III, ISOFORM Q oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 5-Hydroxytryptamine degredation#P04372>Aldehyde Dehydrogenase#P04402 CIOIN|Ensembl=ENSCING00000022080.1|UniProtKB=H2XXA7 H2XXA7 PTHR31912:SF34 IP13529P NOTOCHORD-RELATED PROTEIN CIOIN|Ensembl=ENSCING00000020551.1|UniProtKB=H2XJL8 H2XJL8 PTHR23401:SF0 CYCLIN DEPENDANT KINASE-5 ACTIVATOR CYCLIN-DEPENDENT KINASE 5 ACTIVATOR protein kinase activator activity#GO:0030295;molecular function activator activity#GO:0140677;protein kinase regulator activity#GO:0019887;binding#GO:0005488;molecular function regulator activity#GO:0098772;protein serine/threonine kinase activator activity#GO:0043539;enzyme binding#GO:0019899;protein binding#GO:0005515;enzyme activator activity#GO:0008047;protein kinase binding#GO:0019901;enzyme regulator activity#GO:0030234;kinase regulator activity#GO:0019207;kinase activator activity#GO:0019209;kinase binding#GO:0019900 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 kinase modulator#PC00140;kinase activator#PC00138 CIOIN|Ensembl=ENSCING00000004146.3|UniProtKB=F7BQ94 F7BQ94 LOC101243511 PTHR43069:SF2 FUMARYLACETOACETASE FUMARYLACETOACETASE hydrolase activity#GO:0016787;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;tyrosine metabolic process#GO:0006570;organonitrogen compound catabolic process#GO:1901565;amino acid catabolic process#GO:0009063;organic cyclic compound metabolic process#GO:1901360;aromatic amino acid metabolic process#GO:0009072;nitrogen compound metabolic process#GO:0006807;alpha-amino acid metabolic process#GO:1901605;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;L-amino acid metabolic process#GO:0170033;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;organic hydroxy compound metabolic process#GO:1901615;proteinogenic amino acid metabolic process#GO:0170039;oxoacid metabolic process#GO:0043436;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;aromatic compound catabolic process#GO:0019439;organic cyclic compound catabolic process#GO:1901361;aromatic amino acid family catabolic process#GO:0009074;carboxylic acid metabolic process#GO:0019752;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281;monocarboxylic acid catabolic process#GO:0072329 CIOIN|Ensembl=ENSCING00000016738.2|UniProtKB=F6QZV1 F6QZV1 PTHR35577:SF2 CYSTEINE-RICH, ACIDIC INTEGRAL MEMBRANE PROTEIN-RELATED DYNEIN HEAVY CHAIN CIOIN|Ensembl=ENSCING00000006694.3|UniProtKB=F7ASB7 F7ASB7 PTHR43539:SF23 FLAVIN-BINDING MONOOXYGENASE-LIKE PROTEIN (AFU_ORTHOLOGUE AFUA_4G09220) FAD-DEPENDENT OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN 2 nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;flavin adenine dinucleotide binding#GO:0050660;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;anion binding#GO:0043168;oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497 response to organic substance#GO:0010033;macromolecule catabolic process#GO:0009057;cellular response to stimulus#GO:0051716;response to endoplasmic reticulum stress#GO:0034976;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;response to organonitrogen compound#GO:0010243;ERAD pathway#GO:0036503;cellular process#GO:0009987;primary metabolic process#GO:0044238;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;cellular response to stress#GO:0033554;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;endoplasmic reticulum lumen#GO:0005788;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 oxygenase#PC00177;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000007418.3|UniProtKB=A0A1W5BJ79 A0A1W5BJ79 deaf-1 PTHR10237:SF1 DEFORMED EPIDERMAL AUTOREGULATORY FACTOR 1 HOMOLOG SUPPRESSIN DEFORMED EPIDERMAL AUTOREGULATORY FACTOR 1 HOMOLOG transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 zinc finger transcription factor#PC00244 CIOIN|Ensembl=ENSCING00000012544.2|UniProtKB=F6WLM3 F6WLM3 PTHR11819:SF196 SOLUTE CARRIER FAMILY 5 SODIUM_GLUCOSE COTRANSPORTER 4 inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;carbohydrate transmembrane transporter activity#GO:0015144;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;sugar transmembrane transporter activity#GO:0051119;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;active transmembrane transporter activity#GO:0022804;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;active monoatomic ion transmembrane transporter activity#GO:0022853;monoatomic ion transmembrane transporter activity#GO:0015075;inorganic cation transmembrane transporter activity#GO:0022890;solute:monoatomic cation symporter activity#GO:0015294 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000006184.3|UniProtKB=F7BK20 F7BK20 foxk PTHR45881:SF7 CHECKPOINT SUPPRESSOR 1-LIKE, ISOFORM A-RELATED CHECKPOINT SUPPRESSOR 1-LIKE, ISOFORM A-RELATED sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 CIOIN|Ensembl=ENSCING00000001619.3|UniProtKB=F6RYL0 F6RYL0 PTHR47633:SF3 IMMUNOGLOBULIN STRIATED MUSCLE PREFERENTIALLY EXPRESSED PROTEIN KINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;kinase activity#GO:0016301;protein kinase activity#GO:0004672 CIOIN|Ensembl=ENSCING00000004851.4|UniProtKB=H2XJF3 H2XJF3 PTHR31409:SF0 WASH COMPLEX SUBUNIT 4 WASH COMPLEX SUBUNIT 4 localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;endosome organization#GO:0007032;endosomal transport#GO:0016197;cellular localization#GO:0051641;establishment of localization#GO:0051234;organelle organization#GO:0006996;transport#GO:0006810;endomembrane system organization#GO:0010256;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;vesicle organization#GO:0016050;intracellular transport#GO:0046907;cellular component organization#GO:0016043;cellular process#GO:0009987 cytoplasm#GO:0005737;endosome#GO:0005768;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000019635.1|UniProtKB=H2Y142 H2Y142 PTHR31661:SF1 SIMILAR TO CDNA SEQUENCE BC052040 CDAN1-INTERACTING NUCLEASE 1 CIOIN|Ensembl=ENSCING00000012158.2|UniProtKB=F6UHR3 F6UHR3 PTHR15000:SF1 ERYTHROID DIFFERENTIATION-RELATED FACTOR 1 ERYTHROID DIFFERENTIATION-RELATED FACTOR 1 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;positive regulation of cellular metabolic process#GO:0031325;regulation of RNA biosynthetic process#GO:2001141;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of biosynthetic process#GO:0009889;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;biological regulation#GO:0065007;positive regulation of RNA metabolic process#GO:0051254;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 CIOIN|Ensembl=ENSCING00000000951.3|UniProtKB=A0A1W5BNF9 A0A1W5BNF9 LOC100175978 PTHR23507:SF1 ZGC:174356 FI18259P1-RELATED Endothelin signaling pathway#P00019>Adenylate cyclase#P00569 CIOIN|Ensembl=ENSCING00000004538.3|UniProtKB=F7A8L3 F7A8L3 PTHR13743:SF112 BEIGE/BEACH-RELATED BEACH DOMAIN-CONTAINING PROTEIN scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000004185.3|UniProtKB=F7B5N7 F7B5N7 PTHR22961:SF13 SER/THR PROTEIN KINASE-TRB TRIBBLES enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;binding#GO:0005488;kinase binding#GO:0019900 positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;regulation of catabolic process#GO:0009894;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of proteasomal protein catabolic process#GO:1901800;regulation of protein catabolic process#GO:0042176;regulation of proteolysis involved in protein catabolic process#GO:1903050;regulation of catalytic activity#GO:0050790;positive regulation of proteolysis#GO:0045862;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;positive regulation of metabolic process#GO:0009893;regulation of molecular function#GO:0065009;regulation of protein serine/threonine kinase activity#GO:0071900;regulation of MAP kinase activity#GO:0043405;positive regulation of biological process#GO:0048518;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;positive regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032436;regulation of kinase activity#GO:0043549;regulation of protein kinase activity#GO:0045859;regulation of proteolysis#GO:0030162;positive regulation of proteolysis involved in protein catabolic process#GO:1903052;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060;positive regulation of macromolecule metabolic process#GO:0010604;regulation of primary metabolic process#GO:0080090;regulation of proteasomal protein catabolic process#GO:0061136;positive regulation of protein metabolic process#GO:0051247;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of protein phosphorylation#GO:0001932;biological regulation#GO:0065007;positive regulation of catabolic process#GO:0009896;positive regulation of protein catabolic process#GO:0045732;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 CIOIN|Gene=TRM5_CIOIN|UniProtKB=F7A355 F7A355 PTHR23245:SF36 TRNA METHYLTRANSFERASE TRNA (GUANINE(37)-N1)-METHYLTRANSFERASE tRNA methyltransferase activity#GO:0008175;catalytic activity, acting on RNA#GO:0140098;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;RNA methyltransferase activity#GO:0008173 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA modification#GO:0009451;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;tRNA modification#GO:0006400;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;macromolecule methylation#GO:0043414;tRNA methylation#GO:0030488;organic cyclic compound metabolic process#GO:1901360;methylation#GO:0032259;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;RNA methylation#GO:0001510;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031;RNA methyltransferase#PC00033 CIOIN|Ensembl=ENSCING00000021485.1|UniProtKB=H2XSJ5 H2XSJ5 PTHR10658:SF81 PHOSPHATIDYLINOSITOL TRANSFER PROTEIN PROTEIN RETINAL DEGENERATION B cation binding#GO:0043169;phosphatidylcholine binding#GO:0031210;lipid transfer activity#GO:0120013;small molecule binding#GO:0036094;binding#GO:0005488;phosphatidylcholine transporter activity#GO:0008525;phospholipid transporter activity#GO:0005548;lipid binding#GO:0008289;ion binding#GO:0043167;phosphatidylinositol binding#GO:0035091;phospholipid binding#GO:0005543;transporter activity#GO:0005215;lipid transporter activity#GO:0005319 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 transporter#PC00227 CIOIN|Ensembl=ENSCING00000005920.3|UniProtKB=F6ZHQ8 F6ZHQ8 PTHR24092:SF150 PROBABLE PHOSPHOLIPID-TRANSPORTING ATPASE PHOSPHOLIPID-TRANSPORTING ATPASE ATPase-coupled intramembrane lipid transporter activity#GO:0140326;ATP-dependent activity#GO:0140657;transporter activity#GO:0005215;lipid transporter activity#GO:0005319 organophosphate ester transport#GO:0015748;macromolecule localization#GO:0033036;membrane organization#GO:0061024;transport#GO:0006810;cellular component organization#GO:0016043;regulation of membrane lipid distribution#GO:0097035;phospholipid transport#GO:0015914;cellular process#GO:0009987;lipid transport#GO:0006869;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;biological regulation#GO:0065007;lipid translocation#GO:0034204;lipid localization#GO:0010876;phospholipid translocation#GO:0045332 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 primary active transporter#PC00068;transporter#PC00227 CIOIN|Ensembl=ENSCING00000020430.1|UniProtKB=F6SXF0 F6SXF0 PTHR26312:SF87 TETRATRICOPEPTIDE REPEAT PROTEIN 5 TETRATRICOPEPTIDE REPEAT PROTEIN 5 CIOIN|Ensembl=ENSCING00000008356.3|UniProtKB=F7AKC9 F7AKC9 LOC100177101 PTHR24412:SF401 KELCH PROTEIN FI11917P scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000012346.2|UniProtKB=F6ZTN4 F6ZTN4 LOC100182525 PTHR32123:SF9 BICD FAMILY-LIKE CARGO ADAPTER PROTEIN SPINDLY membrane trafficking regulatory protein#PC00151 CIOIN|Ensembl=ENSCING00000023474.1|UniProtKB=H2XZD2 H2XZD2 PTHR46473:SF26 GH08155P LRRNT DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000021338.1|UniProtKB=H2XXK6 H2XXK6 PTHR14894:SF0 CDK5 REGULATORY SUBUNIT-ASSOCIATED PROTEIN 3 CDK5 REGULATORY SUBUNIT-ASSOCIATED PROTEIN 3 biological regulation#GO:0065007;regulation of biological process#GO:0050789;regulation of cell cycle#GO:0051726;regulation of mitotic cell cycle#GO:0007346;regulation of cellular process#GO:0050794 cellular anatomical entity#GO:0110165;endomembrane system#GO:0012505 CIOIN|Ensembl=ENSCING00000007080.3|UniProtKB=F6WA11 F6WA11 LOC100177287 PTHR13234:SF8 GAMMA-INTERFERON INDUCIBLE LYSOSOMAL THIOL REDUCTASE GILT GAMMA-INTERFERON-INDUCIBLE LYSOSOMAL THIOL REDUCTASE oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 reductase#PC00198;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000013685.2|UniProtKB=F6PWZ1 F6PWZ1 PTHR19325:SF560 COMPLEMENT COMPONENT-RELATED SUSHI DOMAIN-CONTAINING SUSHI, VON WILLEBRAND FACTOR TYPE A, EGF AND PENTRAXIN DOMAIN-CONTAINING PROTEIN 1 complement component#PC00078 CIOIN|Ensembl=ENSCING00000006331.3|UniProtKB=F6PXX9 F6PXX9 PTHR11480:SF3 SAPOSIN-RELATED BCDNA.GH08312 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000019932.1|UniProtKB=H2XP59 H2XP59 PTHR14917:SF4 SPERMATOGENESIS-ASSOCIATED PROTEIN 7 SPERMATOGENESIS-ASSOCIATED 7 microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cellular process#GO:0009987;microtubule-based process#GO:0007017;organelle organization#GO:0006996 axoneme#GO:0005930;microtubule organizing center#GO:0005815;cytoplasmic region#GO:0099568;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;ciliary basal body#GO:0036064;membrane-bounded organelle#GO:0043227;plasma membrane bounded cell projection cytoplasm#GO:0032838;ciliary plasm#GO:0097014;cell projection#GO:0042995;cytoskeleton#GO:0005856;cilium#GO:0005929 CIOIN|Ensembl=ENSCING00000004983.3|UniProtKB=F6W7N8 F6W7N8 PTHR24096:SF267 LONG-CHAIN-FATTY-ACID--COA LIGASE MALONATE--COA LIGASE ACSF3, MITOCHONDRIAL ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877 metabolite interconversion enzyme#PC00262;ligase#PC00142 CIOIN|Ensembl=ENSCING00000005470.3|UniProtKB=F6S6E8 F6S6E8 PTHR45777:SF2 METHIONINE AMINOPEPTIDASE 2 METHIONINE AMINOPEPTIDASE 2 metalloexopeptidase activity#GO:0008235;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;aminopeptidase activity#GO:0004177;exopeptidase activity#GO:0008238;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 protease#PC00190 CIOIN|Ensembl=ENSCING00000014846.2|UniProtKB=F7BGA6 F7BGA6 PTHR31331:SF1 LCCL DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_5G08630) CYSTEINE RICH SECRETORY PROTEIN LCCL DOMAIN CONTAINING 2 CIOIN|Ensembl=ENSCING00000022397.1|UniProtKB=H2XM91 H2XM91 PTHR10953:SF5 UBIQUITIN-ACTIVATING ENZYME E1 SUMO-ACTIVATING ENZYME SUBUNIT 2 ligase activity#GO:0016874;transferase activity#GO:0016740;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877;nucleotidyltransferase activity#GO:0016779;thiosulfate sulfurtransferase activity#GO:0004792;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity, acting on a protein#GO:0140096;sulfurtransferase activity#GO:0016783 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;protein sumoylation#GO:0016925;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;post-translational protein modification#GO:0043687;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 Ubiquitin proteasome pathway#P00060>E1#P01492 CIOIN|Ensembl=ENSCING00000006962.3|UniProtKB=Q4H3C6 Q4H3C6 Ci-Hox4 PTHR45771:SF6 HOMEOTIC PROTEIN DEFORMED HOMEOTIC PROTEIN SEX COMBS REDUCED sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;pattern specification process#GO:0007389;positive regulation of biological process#GO:0048518;regulation of DNA-templated transcription#GO:0006355;multicellular organism development#GO:0007275;regionalization#GO:0003002;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;anatomical structure development#GO:0048856;biological regulation#GO:0065007;anterior/posterior pattern specification#GO:0009952;multicellular organismal process#GO:0032501;positive regulation of RNA metabolic process#GO:0051254;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116 CIOIN|Ensembl=ENSCING00000001304.3|UniProtKB=Q4H394 Q4H394 Ci-large Maf PTHR10129:SF50 TRANSCRIPTION FACTOR MAF BZIP DOMAIN-CONTAINING PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;basic leucine zipper transcription factor#PC00056 CIOIN|Ensembl=ENSCING00000014222.2|UniProtKB=F6Y0W6 F6Y0W6 PTHR10728:SF40 CYTOSOLIC PHOSPHOLIPASE A2 PATATIN FAMILY PROTEIN hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;phospholipase A2 activity#GO:0004623;phospholipase activity#GO:0004620;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;cellular metabolic process#GO:0044237;glycerophospholipid metabolic process#GO:0006650;glycerolipid catabolic process#GO:0046503;lipid catabolic process#GO:0016042;glycerophospholipid catabolic process#GO:0046475;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate catabolic process#GO:0046434;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;phospholipid catabolic process#GO:0009395;catabolic process#GO:0009056;organophosphate metabolic process#GO:0019637;organic substance catabolic process#GO:1901575;cellular lipid metabolic process#GO:0044255;cellular lipid catabolic process#GO:0044242;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 phospholipase#PC00186 CIOIN|Ensembl=ENSCING00000015744.2|UniProtKB=F6VVY9 F6VVY9 PTHR22588:SF3 VWFA DOMAIN-CONTAINING PROTEIN VWFA DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000008371.3|UniProtKB=F7A1R5 F7A1R5 PTHR19849:SF0 PHOSPHOLIPASE A-2-ACTIVATING PROTEIN PHOSPHOLIPASE A-2-ACTIVATING PROTEIN protein binding#GO:0005515;ubiquitin-like protein binding#GO:0032182;binding#GO:0005488;ubiquitin binding#GO:0043130 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;homeostatic process#GO:0042592;cellular homeostasis#GO:0019725;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000008006.3|UniProtKB=F6VHI4 F6VHI4 PTHR45625:SF6 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-RELATED SPLICEOSOME-ASSOCIATED PROTEIN CWC27 HOMOLOG peptidyl-prolyl cis-trans isomerase activity#GO:0003755;isomerase activity#GO:0016853;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;protein peptidyl-prolyl isomerization#GO:0000413;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 ribonucleoprotein complex#GO:1990904;catalytic step 2 spliceosome#GO:0071013;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622 chaperone#PC00072 CIOIN|Ensembl=ENSCING00000005288.3|UniProtKB=F6TUV6 F6TUV6 LOC100177816 PTHR10026:SF8 CYCLIN CYCLIN-H protein kinase regulator activity#GO:0019887;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207 regulation of protein kinase activity#GO:0045859;regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of catalytic activity#GO:0050790;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of phosphorus metabolic process#GO:0051174;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of molecular function#GO:0065009;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;regulation of protein serine/threonine kinase activity#GO:0071900;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cyclin-dependent protein serine/threonine kinase activity#GO:0000079;regulation of kinase activity#GO:0043549;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;DNA-directed RNA polymerase complex#GO:0000428;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;serine/threonine protein kinase complex#GO:1902554;RNA polymerase II transcription regulator complex#GO:0090575;protein kinase complex#GO:1902911;intracellular protein-containing complex#GO:0140535;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695;RNA polymerase II, holoenzyme#GO:0016591;RNA polymerase complex#GO:0030880;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;transcription factor TFIIH holo complex#GO:0005675;nuclear protein-containing complex#GO:0140513 kinase activator#PC00138 CIOIN|Ensembl=ENSCING00000014507.2|UniProtKB=F6YT96 F6YT96 LOC100185235 PTHR20003:SF7 GLYCOPROTEIN-RELATED SGNH DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000020659.1|UniProtKB=H2XJL5 H2XJL5 LOC100183854 PTHR23024:SF24 ARYLACETAMIDE DEACETYLASE ALPHA_BETA HYDROLASE FOLD-3 DOMAIN-CONTAINING PROTEIN deacetylase#PC00087;metabolite interconversion enzyme#PC00262;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000017937.1|UniProtKB=H2XTU1 H2XTU1 PTHR43806:SF7 PEPTIDASE S8 MEMBRANE-BOUND TRANSCRIPTION FACTOR SITE-1 PROTEASE hydrolase activity#GO:0016787;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 serine protease#PC00203;protease#PC00190 CIOIN|Ensembl=ENSCING00000018189.1|UniProtKB=H2XXY1 H2XXY1 PTHR24343:SF348 SERINE/THREONINE KINASE AT25266P transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;phosphorylation#GO:0016310;protein phosphorylation#GO:0006468;cellular process#GO:0009987;protein metabolic process#GO:0019538;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000013161.2|UniProtKB=F6YFE4 F6YFE4 PTHR12308:SF87 ANOCTAMIN ANOCTAMIN inorganic molecular entity transmembrane transporter activity#GO:0015318;chloride channel activity#GO:0005254;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;chloride transmembrane transporter activity#GO:0015108;monoatomic anion transmembrane transporter activity#GO:0008509;inorganic anion transmembrane transporter activity#GO:0015103;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267;monoatomic ion channel activity#GO:0005216 localization#GO:0051179;inorganic anion transmembrane transport#GO:0098661;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic anion transmembrane transport#GO:0098656;monoatomic ion transmembrane transport#GO:0034220;monoatomic anion transport#GO:0006820;transport#GO:0006810;chloride transport#GO:0006821;chloride transmembrane transport#GO:1902476;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 CIOIN|Ensembl=ENSCING00000014847.2|UniProtKB=F7BGA1 F7BGA1 PTHR31331:SF1 LCCL DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_5G08630) CYSTEINE RICH SECRETORY PROTEIN LCCL DOMAIN CONTAINING 2 CIOIN|Ensembl=ENSCING00000015854.2|UniProtKB=F6ZJE6 F6ZJE6 PTHR13438:SF2 AMINOACYL TRNA SYNTHASE COMPLEX-INTERACTING MULTIFUNCTIONAL PROTEIN AMINOACYL TRNA SYNTHASE COMPLEX-INTERACTING MULTIFUNCTIONAL PROTEIN 2 intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;catalytic complex#GO:1902494 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000001897.3|UniProtKB=F7A328 F7A328 LOC100177808 PTHR22895:SF0 ARMADILLO REPEAT-CONTAINING PROTEIN 6 ARMADILLO REPEAT-CONTAINING PROTEIN 6 CIOIN|Ensembl=ENSCING00000006219.3|UniProtKB=F6YW93 F6YW93 LOC100186981 PTHR22792:SF140 LUPUS LA PROTEIN-RELATED ACHILLES, ISOFORM A nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000014238.2|UniProtKB=F6XZJ5 F6XZJ5 LOC100177517 PTHR48407:SF1 CRANIOFACIAL DEVELOPMENT PROTEIN 1 CRANIOFACIAL DEVELOPMENT PROTEIN 1 CIOIN|Ensembl=ENSCING00000007370.3|UniProtKB=F6VCG5 F6VCG5 PTHR12722:SF0 XAP-5 PROTEIN-RELATED PROTEIN FAM50A cellular component organization or biogenesis#GO:0071840;chromatin organization#GO:0006325;protein-DNA complex organization#GO:0071824;cellular component organization#GO:0016043;cellular process#GO:0009987;protein-containing complex organization#GO:0043933 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000002715.3|UniProtKB=F6UDJ0 F6UDJ0 PTHR23270:SF10 PROGRAMMED CELL DEATH PROTEIN 11 PRE-RRNA PROCESSING PROTEIN RRP5 PROTEIN RRP5 HOMOLOG nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 membrane-enclosed lumen#GO:0031974;small-subunit processome#GO:0032040;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;nuclear lumen#GO:0031981 RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000009433.3|UniProtKB=F6TKV3 F6TKV3 PTHR23152:SF4 2-OXOGLUTARATE DEHYDROGENASE 2-OXOADIPATE DEHYDROGENASE COMPLEX COMPONENT E1 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 TCA cycle#P00051>alphaketoglutarate Dehydrogenase#P01269 CIOIN|Ensembl=ENSCING00000022926.1|UniProtKB=H2XNN6 H2XNN6 PTHR47977:SF18 RAS-RELATED PROTEIN RAB RABX5 GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;ion binding#GO:0043167;anion binding#GO:0043168 localization#GO:0051179;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization#GO:0051234;transport#GO:0006810 small GTPase#PC00208;G-protein#PC00020 CIOIN|Ensembl=ENSCING00000013525.2|UniProtKB=F7B0X0 F7B0X0 LOC100177511 PTHR21314:SF0 QUEUOSINE 5'-PHOSPHATE N-GLYCOSYLASE_HYDROLASE-RELATED QUEUOSINE 5'-PHOSPHATE N-GLYCOSYLASE_HYDROLASE cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;tRNA metabolic process#GO:0006399;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;RNA modification#GO:0009451;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;tRNA modification#GO:0006400;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 CIOIN|Ensembl=ENSCING00000004085.3|UniProtKB=F6YI37 F6YI37 PTHR11705:SF91 PROTEASE FAMILY M14 CARBOXYPEPTIDASE A,B FI01817P-RELATED metalloexopeptidase activity#GO:0008235;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;metallocarboxypeptidase activity#GO:0004181;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;carboxypeptidase activity#GO:0004180 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 metalloprotease#PC00153;protease#PC00190 CIOIN|Ensembl=ENSCING00000007171.3|UniProtKB=F6ZAZ4 F6ZAZ4 LOC100177772 PTHR22802:SF379 C-TYPE LECTIN SUPERFAMILY MEMBER CHONDROITIN SULFATE PROTEOGLYCAN 2 ISOFORM X1 membrane traffic protein#PC00150 CIOIN|Ensembl=ENSCING00000001222.3|UniProtKB=F6SYF4 F6SYF4 PTHR42735:SF6 FAMILY NOT NAMED SPHINGOSINE-1-PHOSPHATE LYASE 1 CIOIN|Ensembl=ENSCING00000024222.1|UniProtKB=H2Y260 H2Y260 PTHR24390:SF244 ZINC FINGER PROTEIN LD33778P-RELATED sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 CIOIN|Ensembl=ENSCING00000018201.1|UniProtKB=H2XYK1 H2XYK1 PTHR24024:SF19 PULMONARY SURFACTANT-ASSOCIATED PROTEIN A FARMER, ISOFORM H extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 surfactant#PC00212;structural protein#PC00211 CIOIN|Ensembl=ENSCING00000007439.3|UniProtKB=F7AP23 F7AP23 LOC100181786 PTHR45850:SF2 SORTING NEXIN FAMILY MEMBER SORTING NEXIN-5-LIKE scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000004638.3|UniProtKB=F6RST4 F6RST4 PTHR23065:SF61 PROLINE-SERINE-THREONINE PHOSPHATASE INTERACTING PROTEIN 1 PROLINE-SERINE-THREONINE PHOSPHATASE-INTERACTING PROTEIN 2-LIKE cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;protein-containing complex assembly#GO:0065003;actin polymerization or depolymerization#GO:0008154;actin filament polymerization#GO:0030041;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;protein-containing complex organization#GO:0043933;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;protein polymerization#GO:0051258;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036 supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;cell periphery#GO:0071944;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;organelle#GO:0043226;actin filament#GO:0005884;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cytoskeleton#GO:0005856;plasma membrane#GO:0005886 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 CIOIN|Ensembl=ENSCING00000013955.2|UniProtKB=F6RPS0 F6RPS0 LOC100180310 PTHR20905:SF1 N-ACETYLTRANSFERASE-RELATED AT07410P-RELATED acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;N-acetyltransferase activity#GO:0008080;acyltransferase activity#GO:0016746;acetyltransferase activity#GO:0016407;catalytic activity#GO:0003824;N-acyltransferase activity#GO:0016410 acetyltransferase#PC00038 CIOIN|Ensembl=ENSCING00000001495.3|UniProtKB=F6THF9 F6THF9 PTHR12691:SF10 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 23 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 23 positive regulation of gene expression#GO:0010628;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;positive regulation of macromolecule biosynthetic process#GO:0010557;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;mediator complex#GO:0016592;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031;general transcription factor#PC00259 CIOIN|Ensembl=ENSCING00000009815.3|UniProtKB=F6Y5L1 F6Y5L1 PTHR31698:SF7 LYSOZYME G FAMILY MEMBER PEPTIDASE M15C DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000005075.3|UniProtKB=F6ZLR2 F6ZLR2 PTHR22997:SF6 PIH1 DOMAIN-CONTAINING PROTEIN 1 PIH1 DOMAIN-CONTAINING PROTEIN 2 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;RNA processing#GO:0006396;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;protein-RNA complex assembly#GO:0022618;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;ribosome biogenesis#GO:0042254;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;rRNA metabolic process#GO:0016072;protein-containing complex organization#GO:0043933;ribonucleoprotein complex biogenesis#GO:0022613;protein-RNA complex organization#GO:0071826 cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000006437.3|UniProtKB=F6QLN4 F6QLN4 PTHR12299:SF17 HYALURONIC ACID-BINDING PROTEIN 4 AT19571P-RELATED nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000009118.4|UniProtKB=F6TJV9 F6TJV9 PTHR43599:SF3 MULTIFUNCTIONAL PROTEIN ADE2 SI:DKEY-6E2.2 CIOIN|Ensembl=ENSCING00000009195.3|UniProtKB=F6V934 F6V934 LOC100184556 PTHR46029:SF7 C-TERMINAL-BINDING PROTEIN C-TERMINAL-BINDING PROTEIN molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;transcription coactivator activity#GO:0003713;protein binding#GO:0005515;transcription factor binding#GO:0008134;DNA-binding transcription factor binding#GO:0140297 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transcription cofactor#PC00217 Wnt signaling pathway#P00057>C-terminal Binding Protein#P01439 CIOIN|Ensembl=ENSCING00000001767.3|UniProtKB=F7A3V9 F7A3V9 LOC100181643 PTHR12271:SF40 POLY A POLYMERASE CID PAP -RELATED POLY(A) RNA POLYMERASE GLD2 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;RNA 3'-end processing#GO:0031123;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 nucleotidyltransferase#PC00174 CIOIN|Ensembl=ENSCING00000005475.3|UniProtKB=F6S6I0 F6S6I0 LOC100177907 PTHR35678:SF1 PROTEIN STPG4 PROTEIN STPG4 protein binding#GO:0005515;protein-containing complex binding#GO:0044877;histone binding#GO:0042393;binding#GO:0005488;chromatin binding#GO:0003682 positive regulation of nitrogen compound metabolic process#GO:0051173;protein-DNA complex organization#GO:0071824;regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA metabolic process#GO:0051052;positive regulation of cellular metabolic process#GO:0031325;cellular component organization#GO:0016043;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;epigenetic regulation of gene expression#GO:0040029;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;positive regulation of metabolic process#GO:0009893;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;protein-containing complex organization#GO:0043933;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;chromatin remodeling#GO:0006338;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000019760.1|UniProtKB=F7AWN2 F7AWN2 PTHR19879:SF1 TRANSCRIPTION INITIATION FACTOR TFIID CANNONBALL-RELATED cellular aromatic compound metabolic process#GO:0006725;DNA-templated transcription#GO:0006351;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;RNA biosynthetic process#GO:0032774;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;transcription initiation at RNA polymerase II promoter#GO:0006367;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nucleobase-containing compound biosynthetic process#GO:0034654;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;DNA-templated transcription initiation#GO:0006352;aromatic compound biosynthetic process#GO:0019438;transcription by RNA polymerase II#GO:0006366;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;DNA-directed RNA polymerase complex#GO:0000428;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;transcription factor TFIID complex#GO:0005669;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695;RNA polymerase II, holoenzyme#GO:0016591;RNA polymerase complex#GO:0030880;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 CIOIN|Ensembl=ENSCING00000001326.3|UniProtKB=F6W9U8 F6W9U8 PTHR15090:SF0 SEQUESTOSOME 1-RELATED SEQUESTOSOME-1 K63-linked polyubiquitin modification-dependent protein binding#GO:0070530;binding#GO:0005488;protein binding#GO:0005515;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;modification-dependent protein binding#GO:0140030;polyubiquitin modification-dependent protein binding#GO:0031593;kinase binding#GO:0019900 macroautophagy#GO:0016236;mitophagy#GO:0000423;endomembrane system organization#GO:0010256;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;autophagy of mitochondrion#GO:0000422;cellular process#GO:0009987;organelle disassembly#GO:1903008;process utilizing autophagic mechanism#GO:0061919;cellular component organization or biogenesis#GO:0071840;endosome organization#GO:0007032;cellular component disassembly#GO:0022411;organelle organization#GO:0006996;catabolic process#GO:0009056;vesicle organization#GO:0016050;mitochondrion organization#GO:0007005;autophagy#GO:0006914;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;autophagosome#GO:0005776;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000011992.2|UniProtKB=F6RXH0 F6RXH0 PTHR46501:SF10 MYOMEGALIN CENTROSOMIN regulation of microtubule-based process#GO:0032886;positive regulation of organelle organization#GO:0010638;regulation of organelle organization#GO:0033043;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;centrosome cycle#GO:0007098;regulation of cellular component organization#GO:0051128;cellular component organization#GO:0016043;regulation of microtubule polymerization or depolymerization#GO:0031110;cellular process#GO:0009987;microtubule organizing center organization#GO:0031023;positive regulation of protein polymerization#GO:0032273;positive regulation of cellular process#GO:0048522;regulation of supramolecular fiber organization#GO:1902903;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of cytoskeleton organization#GO:0051493;regulation of protein-containing complex assembly#GO:0043254;microtubule-based process#GO:0007017;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;regulation of cellular component biogenesis#GO:0044087;regulation of microtubule cytoskeleton organization#GO:0070507;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;cell cycle#GO:0007049;cytoskeleton organization#GO:0007010;positive regulation of cellular component biogenesis#GO:0044089;regulation of protein polymerization#GO:0032271;positive regulation of biological process#GO:0048518 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;microtubule cytoskeleton#GO:0015630;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000006364.3|UniProtKB=F6RRI2 F6RRI2 PTHR21646:SF33 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 22 cysteine protease#PC00081;protease#PC00190 CIOIN|Ensembl=ENSCING00000011737.2|UniProtKB=F6TX66 F6TX66 LOC100175469 PTHR10366:SF853 NAD DEPENDENT EPIMERASE/DEHYDRATASE GH25466P oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 dehydratase#PC00091;lyase#PC00144 CIOIN|Ensembl=ENSCING00000023572.1|UniProtKB=H2XR98 H2XR98 PTHR43671:SF13 SERINE/THREONINE-PROTEIN KINASE NEK SERINE_THREONINE-PROTEIN KINASE NEK2 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000008182.3|UniProtKB=F6PJX3 F6PJX3 PTHR11946:SF71 VALYL-TRNA SYNTHETASES VALINE--TRNA LIGASE, MITOCHONDRIAL catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;ligase activity#GO:0016874;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;peptide biosynthetic process#GO:0043043;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 aminoacyl-tRNA synthetase#PC00047;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000000101.3|UniProtKB=F6T5M6 F6T5M6 LOC100177401 PTHR25480:SF0 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 73 C-MAF-INDUCING PROTEIN CIOIN|Ensembl=ENSCING00000002699.3|UniProtKB=F6X139 F6X139 PTHR43084:SF1 PERSULFIDE DIOXYGENASE ETHE1 PERSULFIDE DIOXYGENASE ETHE1, MITOCHONDRIAL oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;dioxygenase activity#GO:0051213 sulfur compound metabolic process#GO:0006790;nitrogen compound metabolic process#GO:0006807;peptide metabolic process#GO:0006518;cellular modified amino acid metabolic process#GO:0006575;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular process#GO:0009987;glutathione metabolic process#GO:0006749;amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 oxygenase#PC00177;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000017382.2|UniProtKB=F6X0B6 F6X0B6 PTHR43677:SF4 SHORT-CHAIN DEHYDROGENASE/REDUCTASE QUINONE OXIDOREDUCTASE-LIKE PROTEIN 2 oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 Huntington disease#P00029>PIG3#G01535 CIOIN|Ensembl=ENSCING00000005061.3|UniProtKB=F6ZRE8 F6ZRE8 PTHR12245:SF11 SPRY DOMAIN CONTAINING SOCS BOX PROTEIN PROTEIN GUSTAVUS macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 SCF ubiquitin ligase complex#GO:0019005;intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;cullin-RING ubiquitin ligase complex#GO:0031461;transferase complex#GO:1990234 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000007647.3|UniProtKB=F6VXC2 F6VXC2 PTHR44329:SF291 SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED PROTEIN KINASE DOMAIN-CONTAINING PROTEIN MAP kinase kinase kinase activity#GO:0004709;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000005509.3|UniProtKB=F7AV41 F7AV41 PTHR44324:SF3 WD40 REPEAT DOMAIN 95 WD REPEAT-CONTAINING PROTEIN 49-LIKE CIOIN|Ensembl=ENSCING00000014206.2|UniProtKB=F6ZPA1 F6ZPA1 LOC100184299 PTHR31649:SF1 AGAP009604-PA FARNESOIC ACID O-METHYL TRANSFERASE DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000003655.3|UniProtKB=F7AXN3 F7AXN3 PTHR24031:SF91 RNA HELICASE ATP-DEPENDENT RNA HELICASE DDX24 intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA helicase#PC00032 CIOIN|Ensembl=ENSCING00000007428.3|UniProtKB=F7B7U2 F7B7U2 PTHR15398:SF4 BROMODOMAIN-CONTAINING PROTEIN 8 BROMODOMAIN-CONTAINING PROTEIN 8 ISOFORM X1 CIOIN|Ensembl=ENSCING00000024495.1|UniProtKB=H2XW45 H2XW45 LOC100176528 PTHR45732:SF7 ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 8 ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 8 Huntington disease#P00029>ARF#P00786 CIOIN|Ensembl=ENSCING00000002504.3|UniProtKB=F6YEQ8 F6YEQ8 LOC100175728 PTHR13227:SF0 EUKARYOTIC TRANSLATION INITIATION FACTOR 2A EUKARYOTIC TRANSLATION INITIATION FACTOR 2A tRNA binding#GO:0000049;nucleic acid binding#GO:0003676;translation regulator activity#GO:0045182;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159;translation initiation factor activity#GO:0003743;ribonucleoprotein complex binding#GO:0043021;ribosome binding#GO:0043022;mRNA binding#GO:0003729;protein-containing complex binding#GO:0044877;translation regulator activity, nucleic acid binding#GO:0090079;translation factor activity, RNA binding#GO:0008135 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic small ribosomal subunit#GO:0022627;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;small ribosomal subunit#GO:0015935;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;ribosomal subunit#GO:0044391 translation initiation factor#PC00224;translation factor#PC00223;translational protein#PC00263 Gonadotropin-releasing hormone receptor pathway#P06664>EIF2A#P06762 CIOIN|Ensembl=ENSCING00000018011.1|UniProtKB=H2XXG9 H2XXG9 PTHR24064:SF577 SOLUTE CARRIER FAMILY 22 MEMBER GH09241P secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000011345.2|UniProtKB=F6UXI9 F6UXI9 LOC100180193 PTHR23011:SF38 CYCLIC NUCLEOTIDE-BINDING DOMAIN CONTAINING PROTEIN CYCLIC NUCLEOTIDE-BINDING DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000008408.3|UniProtKB=F6XRM1 F6XRM1 PTHR13164:SF3 CALICYLIN BINDING PROTEIN CALCYCLIN-BINDING PROTEIN membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000004861.3|UniProtKB=F6TCA9 F6TCA9 zf(c2h2)-12 PTHR24379:SF121 KRAB AND ZINC FINGER DOMAIN-CONTAINING C2H2-TYPE DOMAIN-CONTAINING PROTEIN C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 CIOIN|Ensembl=ENSCING00000000728.3|UniProtKB=F6WWM2 F6WWM2 PTHR23302:SF40 TRANSMEMBRANE CHANNEL-RELATED TRANSMEMBRANE CHANNEL-LIKE PROTEIN passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;channel activity#GO:0015267;gated channel activity#GO:0022836;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 ion channel#PC00133;transporter#PC00227 CIOIN|Ensembl=ENSCING00000023735.1|UniProtKB=Q19AW1 Q19AW1 Phox2 PTHR24329:SF543 HOMEOBOX PROTEIN ARISTALESS FI01017P-RELATED sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 CIOIN|Ensembl=ENSCING00000020984.1|UniProtKB=H2XU78 H2XU78 PTHR19325:SF571 COMPLEMENT COMPONENT-RELATED SUSHI DOMAIN-CONTAINING SUSHI DOMAIN-CONTAINING PROTEIN complement component#PC00078 CIOIN|Ensembl=ENSCING00000004346.3|UniProtKB=F7BMN7 F7BMN7 LOC100181934 PTHR12311:SF7 ACTIVATOR OF BASAL TRANSCRIPTION 1 ACTIVATOR OF BASAL TRANSCRIPTION 1 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;RNA processing#GO:0006396;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;protein-RNA complex assembly#GO:0022618;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;ribosome biogenesis#GO:0042254;non-membrane-bounded organelle assembly#GO:0140694;maturation of 5.8S rRNA#GO:0000460;endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000447;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular component organization#GO:0016043;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;protein-RNA complex organization#GO:0071826;maturation of SSU-rRNA#GO:0030490;ribosomal small subunit biogenesis#GO:0042274 intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000001757.2|UniProtKB=F7AM41 F7AM41 PTHR24229:SF109 NEUROPEPTIDES RECEPTOR SOMATOSTATIN RECEPTOR TYPE 2-LIKE neuropeptide binding#GO:0042923;signaling receptor activity#GO:0038023;binding#GO:0005488;peptide binding#GO:0042277;amide binding#GO:0033218;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;neuropeptide signaling pathway#GO:0007218;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;neuron projection#GO:0043005;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 CIOIN|Ensembl=ENSCING00000007277.3|UniProtKB=F6SVP7 F6SVP7 LOC100184413 PTHR13326:SF21 TRNA PSEUDOURIDINE SYNTHASE D PSEUDOURIDYLATE SYNTHASE PUS7L isomerase activity#GO:0016853;intramolecular transferase activity#GO:0016866;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;RNA modification#GO:0009451;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;pseudouridine synthesis#GO:0001522;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 CIOIN|Ensembl=ENSCING00000001929.2|UniProtKB=F6ZIP8 F6ZIP8 PTHR11938:SF91 FAD NADPH DEHYDROGENASE/OXIDOREDUCTASE NADPH:ADRENODOXIN OXIDOREDUCTASE, MITOCHONDRIAL oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 oxidoreductase#PC00176 Vitamin D metabolism and pathway#P04396>FdxR#P04604 CIOIN|Ensembl=ENSCING00000008674.3|UniProtKB=F6XML2 F6XML2 PTHR11145:SF8 BTB/POZ DOMAIN-CONTAINING ADAPTER FOR CUL3-MEDIATED RHOA DEGRADATION PROTEIN FAMILY MEMBER RE57120P scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000004029.3|UniProtKB=F6SKG8 F6SKG8 PTHR11010:SF117 PROTEASE S28 PRO-X CARBOXYPEPTIDASE-RELATED SERINE PROTEASE 16 hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 serine protease#PC00203;protease#PC00190 CIOIN|Ensembl=ENSCING00000004282.3|UniProtKB=F6TT18 F6TT18 LOC100175596 PTHR19269:SF79 TROPOMYOSIN TROPOMYOSIN ALPHA-3 CHAIN cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;system process#GO:0003008;actin filament organization#GO:0007015;multicellular organismal process#GO:0032501;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987;muscle system process#GO:0003012;muscle contraction#GO:0006936 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;actin filament#GO:0005884;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;actin binding motor protein#PC00040 CIOIN|Ensembl=ENSCING00000006167.3|UniProtKB=F6SDM6 F6SDM6 PTHR23180:SF399 CENTAURIN/ARF BLOWN FUSE, ISOFORM A-RELATED CIOIN|Ensembl=ENSCING00000002679.3|UniProtKB=F6XPZ4 F6XPZ4 LOC100177214 PTHR10126:SF42 TATA-BOX BINDING PROTEIN TATA-BOX-BINDING PROTEIN cellular aromatic compound metabolic process#GO:0006725;DNA-templated transcription#GO:0006351;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;gene expression#GO:0010467;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;DNA-templated transcription initiation#GO:0006352;aromatic compound biosynthetic process#GO:0019438;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 RNA metabolism protein#PC00031;general transcription factor#PC00259 General transcription by RNA polymerase I#P00022>SL1 complex#P00653;Huntington disease#P00029>TBP#P00779;General transcription by RNA polymerase I#P00022>TBP#P00657;Transcription regulation by bZIP transcription factor#P00055>TBP#P01399 CIOIN|Ensembl=ENSCING00000007807.3|UniProtKB=F6WHQ9 F6WHQ9 LOC100179079 PTHR45710:SF34 C-TYPE LECTIN DOMAIN-CONTAINING PROTEIN 180 SUBFAMILY NOT NAMED defense/immunity protein#PC00090 CIOIN|Ensembl=ENSCING00000006416.3|UniProtKB=F6QSH0 F6QSH0 PTHR13108:SF9 CONDENSIN COMPLEX SUBUNIT 2 CONDENSIN COMPLEX SUBUNIT 2 protein-containing complex binding#GO:0044877;binding#GO:0005488;chromatin binding#GO:0003682 nuclear chromosome segregation#GO:0098813;sister chromatid segregation#GO:0000819;nuclear division#GO:0000280;cell cycle process#GO:0022402;chromosome condensation#GO:0030261;cellular component organization#GO:0016043;cellular process#GO:0009987;mitotic cell cycle process#GO:1903047;chromosome segregation#GO:0007059;mitotic chromosome condensation#GO:0007076;cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;chromosome organization#GO:0051276;organelle organization#GO:0006996;cell cycle#GO:0007049;mitotic nuclear division#GO:0140014;organelle fission#GO:0048285;mitotic sister chromatid segregation#GO:0000070 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000014674.2|UniProtKB=F6ZWC8 F6ZWC8 PTHR46303:SF1 VWFC DOMAIN-CONTAINING PROTEIN VWFC DOMAIN-CONTAINING PROTEIN protein binding#GO:0005515;binding#GO:0005488;cytokine binding#GO:0019955 regulation of cell communication#GO:0010646;cellular developmental process#GO:0048869;negative regulation of biological process#GO:0048519;negative regulation of response to stimulus#GO:0048585;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;developmental process#GO:0032502;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;regulation of BMP signaling pathway#GO:0030510;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;negative regulation of BMP signaling pathway#GO:0030514;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cellular response to growth factor stimulus#GO:0090287;negative regulation of signal transduction#GO:0009968;negative regulation of cell communication#GO:0010648;negative regulation of cellular process#GO:0048523 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 CIOIN|Ensembl=ENSCING00000014370.2|UniProtKB=F7AGA2 F7AGA2 LOC100185963 PTHR22776:SF49 MARVEL-CONTAINING POTENTIAL LIPID RAFT-ASSOCIATED PROTEIN MARVEL DOMAIN-CONTAINING PROTEIN cellular anatomical entity#GO:0110165;membrane#GO:0016020 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000011584.2|UniProtKB=F7AP11 F7AP11 PTHR13050:SF7 USE1-LIKE PROTEIN VESICLE TRANSPORT PROTEIN USE1 molecular adaptor activity#GO:0060090;SNAP receptor activity#GO:0005484;protein-macromolecule adaptor activity#GO:0030674 localization#GO:0051179;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization#GO:0051234;Golgi vesicle transport#GO:0048193;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;transport#GO:0006810 cytoplasm#GO:0005737;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;SNARE complex#GO:0031201;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000005511.3|UniProtKB=F7AU99 F7AU99 PTHR10201:SF331 MATRIX METALLOPROTEINASE MATRIX METALLOPROTEINASE-14-LIKE ISOFORM X1 hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular component organization or biogenesis#GO:0071840;extracellular structure organization#GO:0043062;external encapsulating structure organization#GO:0045229;catabolic process#GO:0009056;cellular component organization#GO:0016043;cellular process#GO:0009987;extracellular matrix organization#GO:0030198;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000001504.3|UniProtKB=F6SVK8 F6SVK8 LOC100178840 PTHR46819:SF1 EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 7 EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 7 calmodulin-related#PC00061 CIOIN|Ensembl=ENSCING00000011918.2|UniProtKB=F6XIK1 F6XIK1 PTHR14871:SF1 DYNEIN REGULATORY COMPLEX PROTEIN 9 DYNEIN REGULATORY COMPLEX PROTEIN 9 cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782;cellular component organization#GO:0016043;cellular process#GO:0009987;cell projection organization#GO:0030030;organelle organization#GO:0006996;plasma membrane bounded cell projection organization#GO:0120036 cytoplasm#GO:0005737;motile cilium#GO:0031514;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;cilium#GO:0005929;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;microtubule or microtubule-binding cytoskeletal protein#PC00157 CIOIN|Ensembl=ENSCING00000018169.1|UniProtKB=H2XMY4 H2XMY4 LOC100177090 PTHR12560:SF58 LONGEVITY ASSURANCE FACTOR 1 LAG1 CERAMIDE SYNTHASE 1 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity#GO:0003824;N-acyltransferase activity#GO:0016410 lipid metabolic process#GO:0006629;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;membrane lipid biosynthetic process#GO:0046467;sphingolipid metabolic process#GO:0006665;ceramide metabolic process#GO:0006672;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;membrane lipid metabolic process#GO:0006643;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;ceramide biosynthetic process#GO:0046513;cellular lipid metabolic process#GO:0044255;amide metabolic process#GO:0043603;sphingolipid biosynthetic process#GO:0030148;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 transferase#PC00220;metabolite interconversion enzyme#PC00262 TGF-beta signaling pathway#P00052>TGFbeta#P01286 CIOIN|Ensembl=ENSCING00000004505.3|UniProtKB=F7ASZ2 F7ASZ2 LOC100176174 PTHR10476:SF1 CHARGED MULTIVESICULAR BODY PROTEIN CHARGED MULTIVESICULAR BODY PROTEIN 3 membrane traffic protein#PC00150 CIOIN|Ensembl=ENSCING00000001161.2|UniProtKB=F6YAZ4 F6YAZ4 LOC100184966 PTHR23428:SF349 HISTONE H2B HISTONE H2B chromatin/chromatin-binding, or -regulatory protein#PC00077 CIOIN|Ensembl=ENSCING00000019101.1|UniProtKB=H2XZ89 H2XZ89 LOC100180715 PTHR13551:SF1 BRAIN PROTEIN I3 MEMBRANE PROTEIN BRI3 CIOIN|Ensembl=ENSCING00000005394.3|UniProtKB=F6ZA03 F6ZA03 LOC100181332 PTHR13003:SF2 NUP107-RELATED NUCLEAR PORE COMPLEX PROTEIN NUP107 structural molecule activity#GO:0005198;structural constituent of nuclear pore#GO:0017056 cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;protein localization to nucleus#GO:0034504;nucleic acid transport#GO:0050657;nitrogen compound transport#GO:0071705;gene expression#GO:0010467;biosynthetic process#GO:0009058;establishment of protein localization#GO:0045184;RNA localization#GO:0006403;organic substance transport#GO:0071702;protein import into nucleus#GO:0006606;transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery#GO:0000972;establishment of localization#GO:0051234;RNA transport#GO:0050658;protein localization to organelle#GO:0033365;nuclear transport#GO:0051169;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;mRNA export from nucleus#GO:0006406;macromolecule biosynthetic process#GO:0009059;establishment of RNA localization#GO:0051236;macromolecule metabolic process#GO:0043170;establishment of protein localization to organelle#GO:0072594;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;mRNA transport#GO:0051028;cellular process#GO:0009987;post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery#GO:0000973;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;nuclear export#GO:0051168;nucleocytoplasmic transport#GO:0006913;organelle organization#GO:0006996;chromosome organization#GO:0051276;nucleobase-containing compound transport#GO:0015931;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;import into nucleus#GO:0051170 envelope#GO:0031975;nuclear pore#GO:0005643;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear envelope#GO:0005635;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;organelle envelope#GO:0031967;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transporter#PC00227 CIOIN|Ensembl=ENSCING00000024629.1|UniProtKB=H2XXR0 H2XXR0 LOC100185636 PTHR24300:SF397 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 2U1 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;tetrapyrrole binding#GO:0046906;steroid hydroxylase activity#GO:0008395;oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497;heme binding#GO:0020037 response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;response to chemical#GO:0042221;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 oxygenase#PC00177;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000009011.3|UniProtKB=F6RCK1 F6RCK1 PTHR45727:SF3 NPC INTRACELLULAR CHOLESTEROL TRANSPORTER 1 NPC1-LIKE INTRACELLULAR CHOLESTEROL TRANSPORTER 1 small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;steroid binding#GO:0005496;sterol binding#GO:0032934;lipid binding#GO:0008289;alcohol binding#GO:0043178;cholesterol binding#GO:0015485 organic hydroxy compound transport#GO:0015850;macromolecule localization#GO:0033036;sterol transport#GO:0015918;transport#GO:0006810;system process#GO:0003008;homeostatic process#GO:0042592;chemical homeostasis#GO:0048878;cholesterol homeostasis#GO:0042632;lipid transport#GO:0006869;localization#GO:0051179;cholesterol transport#GO:0030301;organic substance transport#GO:0071702;digestion#GO:0007586;establishment of localization#GO:0051234;lipid homeostasis#GO:0055088;multicellular organismal process#GO:0032501;lipid localization#GO:0010876 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 CIOIN|Ensembl=ENSCING00000021351.1|UniProtKB=H2XUJ2 H2XUJ2 LOC100181271 PTHR22997:SF6 PIH1 DOMAIN-CONTAINING PROTEIN 1 PIH1 DOMAIN-CONTAINING PROTEIN 2 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;RNA processing#GO:0006396;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;protein-RNA complex assembly#GO:0022618;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;ribosome biogenesis#GO:0042254;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;rRNA metabolic process#GO:0016072;protein-containing complex organization#GO:0043933;ribonucleoprotein complex biogenesis#GO:0022613;protein-RNA complex organization#GO:0071826 cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000022735.1|UniProtKB=H2XTI5 H2XTI5 LOC100178916 PTHR21580:SF21 SHIPPO-1-RELATED O(6)-METHYLGUANINE-INDUCED APOPTOSIS 2 apoptotic mitochondrial changes#GO:0008637;membrane organization#GO:0061024;transport#GO:0006810;programmed cell death#GO:0012501;cellular component organization#GO:0016043;cellular process#GO:0009987;mitochondrial transport#GO:0006839;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;organelle organization#GO:0006996;apoptotic process#GO:0006915;biological regulation#GO:0065007;cell death#GO:0008219;mitochondrial membrane organization#GO:0007006;mitochondrion organization#GO:0007005 structural protein#PC00211 CIOIN|Ensembl=ENSCING00000013562.2|UniProtKB=F6YBZ2 F6YBZ2 PTHR14453:SF107 PARP/ZINC FINGER CCCH TYPE DOMAIN CONTAINING PROTEIN POLY [ADP-RIBOSE] POLYMERASE molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;transcription corepressor activity#GO:0003714;catalytic activity#GO:0003824;protein-macromolecule adaptor activity#GO:0030674;catalytic activity, acting on a protein#GO:0140096;pentosyltransferase activity#GO:0016763 negative regulation of gene expression#GO:0010629;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of biosynthetic process#GO:0009890;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;negative regulation of metabolic process#GO:0009892;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biosynthetic process#GO:0009889;nitrogen compound metabolic process#GO:0006807;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000019685.1|UniProtKB=F7B8D7 F7B8D7 PTHR24412:SF272 KELCH PROTEIN KELCH-LIKE PROTEIN DIABLO scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000008713.3|UniProtKB=F6WCB0 F6WCB0 LOC100178663 PTHR12534:SF0 30S RIBOSOMAL PROTEIN S2 PROKARYOTIC AND ORGANELLAR SMALL RIBOSOMAL SUBUNIT PROTEIN US2M structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;translation#GO:0006412;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 ribosomal protein#PC00202;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000005247.2|UniProtKB=F6XVG4 F6XVG4 PTHR12934:SF11 50S RIBOSOMAL PROTEIN L15 LARGE RIBOSOMAL SUBUNIT PROTEIN UL15M structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 ribosomal protein#PC00202;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000001104.3|UniProtKB=F7AG70 F7AG70 LOC100176485 PTHR19890:SF10 FIBROBLAST GROWTH FACTOR RECEPTOR FIBROBLAST GROWTH FACTOR RECEPTOR-LIKE 1 transmembrane signal receptor#PC00197;tyrosine protein kinase receptor#PC00233 CIOIN|Ensembl=ENSCING00000024964.1|UniProtKB=H2XZ80 H2XZ80 PTHR24064:SF577 SOLUTE CARRIER FAMILY 22 MEMBER GH09241P secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000000838|UniProtKB=O76808 O76808 Su(H) PTHR10665:SF0 RECOMBINING BINDING PROTEIN SUPPRESSOR OF HAIRLESS SUPPRESSOR OF HAIRLESS PROTEIN cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 Rel homology transcription factor#PC00252;immunoglobulin fold transcription factor#PC00251 Notch signaling pathway#P00045>Su(H)#P01101;Alzheimer disease-presenilin pathway#P00004>CSL#P00158;Angiogenesis#P00005>CSL#P00233 CIOIN|Ensembl=ENSCING00000003744.3|UniProtKB=F6U6L5 F6U6L5 LOC100187496 PTHR43561:SF3 FAMILY NOT NAMED HYDROXYACYL-COENZYME A DEHYDROGENASE, MITOCHONDRIAL oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 lipid metabolic process#GO:0006629;oxoacid metabolic process#GO:0043436;cellular metabolic process#GO:0044237;lipid oxidation#GO:0034440;lipid modification#GO:0030258;lipid catabolic process#GO:0016042;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;fatty acid catabolic process#GO:0009062;primary metabolic process#GO:0044238;fatty acid metabolic process#GO:0006631;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;fatty acid beta-oxidation#GO:0006635;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;cellular lipid metabolic process#GO:0044255;carboxylic acid catabolic process#GO:0046395;cellular lipid catabolic process#GO:0044242;carboxylic acid metabolic process#GO:0019752;cellular catabolic process#GO:0044248;monocarboxylic acid catabolic process#GO:0072329;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 CIOIN|Ensembl=ENSCING00000011756.2|UniProtKB=F6TAB1 F6TAB1 PTHR34400:SF4 FAMILY NOT NAMED MEMBRANE PROTEIN CIOIN|Ensembl=ENSCING00000001422.3|UniProtKB=A0A1W2W6U9 A0A1W2W6U9 LOC100177697 PTHR10844:SF32 CAVEOLIN CAVEOLIN-3-LIKE cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;membrane assembly#GO:0071709;membrane organization#GO:0061024;plasma membrane organization#GO:0007009;endomembrane system organization#GO:0010256;cellular component organization#GO:0016043;cellular process#GO:0009987 plasma membrane raft#GO:0044853;caveola#GO:0005901;plasma membrane region#GO:0098590;membrane raft#GO:0045121;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;membrane microdomain#GO:0098857;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000024165.1|UniProtKB=H2XJR2 H2XJR2 PTHR24322:SF746 PKSB SHORT CHAIN DEHYDROGENASE_REDUCTASE FAMILY 16C MEMBER 5 oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;lipid droplet#GO:0005811;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 dehydrogenase#PC00092;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000021285.1|UniProtKB=H2XRU0 H2XRU0 PTHR14146:SF0 EXOCYST COMPLEX COMPONENT 4 EXOCYST COMPLEX COMPONENT 4 localization#GO:0051179;localization within membrane#GO:0051668;cellular localization#GO:0051641;vesicle-mediated transport to the plasma membrane#GO:0098876;exocytosis#GO:0006887;establishment of localization#GO:0051234;secretion#GO:0046903;post-Golgi vesicle-mediated transport#GO:0006892;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;Golgi to plasma membrane transport#GO:0006893;export from cell#GO:0140352;secretion by cell#GO:0032940 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;vesicle tethering complex#GO:0099023;exocyst#GO:0000145;cell cortex#GO:0005938;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150 CIOIN|Ensembl=ENSCING00000016470.2|UniProtKB=F6WDF7 F6WDF7 LOC113474034 PTHR42884:SF3 PROPROTEIN CONVERTASE SUBTILISIN/KEXIN-RELATED FURIN-LIKE PROTEASE 1, ISOFORMS 1_1-X_2 hydrolase activity#GO:0016787;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;protein processing#GO:0016485;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 bounding membrane of organelle#GO:0098588;trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791;Golgi membrane#GO:0000139 serine protease#PC00203;protein modifying enzyme#PC00260 Activin beta signaling pathway#P06210>FUR1#P06238;Endothelin signaling pathway#P00019>furin#P00575;GBB signaling pathway#P06214>FUR1#P06298;SCW signaling pathway#P06216>FUR1#P06333;DPP-SCW signaling pathway#P06212>FUR1#P06263;DPP signaling pathway#P06213>FUR1#P06290;ALP23B signaling pathway#P06209>FUR1#P06227;Alzheimer disease-amyloid secretase pathway#P00003>Furin#P00105;BMP/activin signaling pathway-drosophila#P06211>Furin#P06244;Alzheimer disease-presenilin pathway#P00004>Furin#P00157;MYO signaling pathway#P06215>FUR1#P06318 CIOIN|Ensembl=ENSCING00000001637.3|UniProtKB=F7B7R9 F7B7R9 PTHR11388:SF142 ORGANIC ANION TRANSPORTER SOLUTE CARRIER ORGANIC ANION TRANSPORTER FAMILY MEMBER 5A1 secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 localization#GO:0051179;organic substance transport#GO:0071702;establishment of localization#GO:0051234;organic anion transport#GO:0015711;transport#GO:0006810 basal plasma membrane#GO:0009925;basolateral plasma membrane#GO:0016323;plasma membrane region#GO:0098590;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;basal part of cell#GO:0045178;plasma membrane#GO:0005886 transporter#PC00227 CIOIN|Ensembl=ENSCING00000011539.2|UniProtKB=F6W7P7 F6W7P7 LOC100185389 PTHR15191:SF3 PROTEIN CBG20567 PITUITARY TUMOR-TRANSFORMING GENE PROTEIN-BINDING FACTOR cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;protein localization to nucleus#GO:0034504;nitrogen compound transport#GO:0071705;establishment of protein localization to organelle#GO:0072594;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;protein import into nucleus#GO:0006606;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;protein localization to organelle#GO:0033365;nuclear transport#GO:0051169;import into nucleus#GO:0051170 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000016251.2|UniProtKB=F6ZBY5 F6ZBY5 LOC100182021 PTHR21021:SF16 GAF/PUTATIVE CYTOSKELETAL PROTEIN TIP41-LIKE PROTEIN oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;regulation of phosphatase activity#GO:0010921;regulation of dephosphorylation#GO:0035303;cell communication#GO:0007154;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;regulation of macromolecule metabolic process#GO:0060255;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of hydrolase activity#GO:0051336;intracellular signal transduction#GO:0035556;signaling#GO:0023052;regulation of metabolic process#GO:0019222;TOR signaling#GO:0031929;regulation of phosphoprotein phosphatase activity#GO:0043666;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000019075.1|UniProtKB=H2XNM8 H2XNM8 PTHR24256:SF545 TRYPTASE-RELATED INACTIVE SERINE PROTEASE 54 hydrolase activity#GO:0016787;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 serine protease#PC00203;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000000473.3|UniProtKB=F6YVR5 F6YVR5 LOC100176203 PTHR31743:SF1 TRANSIENT RECEPTOR POTENTIAL CHANNEL 4-ASSOCIATED PROTEIN TCPC4AP SHORT TRANSIENT RECEPTOR POTENTIAL CHANNEL 4-ASSOCIATED PROTEIN phosphatase binding#GO:0019902;enzyme binding#GO:0019899;protein binding#GO:0005515;binding#GO:0005488 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;cullin-RING ubiquitin ligase complex#GO:0031461;transferase complex#GO:1990234;Cul4-RING E3 ubiquitin ligase complex#GO:0080008 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000023652.1|UniProtKB=H2XY07 H2XY07 PTHR43294:SF13 SODIUM/POTASSIUM-TRANSPORTING ATPASE SUBUNIT ALPHA SODIUM_POTASSIUM-TRANSPORTING ATPASE SUBUNIT ALPHA inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium ion transmembrane transporter activity#GO:0015079;sodium ion transmembrane transporter activity#GO:0015081;P-type ion transporter activity#GO:0015662;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;ATPase-coupled transmembrane transporter activity#GO:0042626;monoatomic cation transmembrane transporter activity#GO:0008324;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;primary active transmembrane transporter activity#GO:0015399;ATP-dependent activity#GO:0140657;metal ion transmembrane transporter activity#GO:0046873;active monoatomic ion transmembrane transporter activity#GO:0022853;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion transmembrane transporter activity#GO:0015075 inorganic ion homeostasis#GO:0098771;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;proton transmembrane transport#GO:1902600;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;sodium ion homeostasis#GO:0055078;monoatomic cation homeostasis#GO:0055080;homeostatic process#GO:0042592;inorganic ion transmembrane transport#GO:0098660;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;cellular process#GO:0009987;intracellular chemical homeostasis#GO:0055082;monoatomic ion homeostasis#GO:0050801;localization#GO:0051179;import across plasma membrane#GO:0098739;sodium ion transport#GO:0006814;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;intracellular monoatomic cation homeostasis#GO:0030003;potassium ion transmembrane transport#GO:0071805;monoatomic cation transport#GO:0006812;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion transport#GO:0006811;import into cell#GO:0098657;monoatomic cation transmembrane transport#GO:0098655;export from cell#GO:0140352;sodium ion transmembrane transport#GO:0035725;potassium ion import across plasma membrane#GO:1990573;potassium ion transport#GO:0006813 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 primary active transporter#PC00068;transporter#PC00227 CIOIN|Ensembl=ENSCING00000003470.3|UniProtKB=F6UAX0 F6UAX0 PTHR24390:SF237 ZINC FINGER PROTEIN FI23536P1-RELATED sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 CIOIN|Ensembl=ENSCING00000021957.1|UniProtKB=H2XS09 H2XS09 LOC100186865 PTHR22776:SF49 MARVEL-CONTAINING POTENTIAL LIPID RAFT-ASSOCIATED PROTEIN MARVEL DOMAIN-CONTAINING PROTEIN cellular anatomical entity#GO:0110165;membrane#GO:0016020 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000017931.1|UniProtKB=H2XQ24 H2XQ24 PTHR12191:SF37 SOLUTE CARRIER FAMILY 39 ZINC TRANSPORTER FOI secondary active transmembrane transporter activity#GO:0015291;inorganic molecular entity transmembrane transporter activity#GO:0015318;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;symporter activity#GO:0015293;active monoatomic ion transmembrane transporter activity#GO:0022853;organic anion transmembrane transporter activity#GO:0008514;monoatomic cation transmembrane transporter activity#GO:0008324;inorganic cation transmembrane transporter activity#GO:0022890;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;homeostatic process#GO:0042592;monoatomic cation homeostasis#GO:0055080;inorganic ion transmembrane transport#GO:0098660;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;cellular process#GO:0009987;intracellular chemical homeostasis#GO:0055082;monoatomic ion homeostasis#GO:0050801;localization#GO:0051179;import across plasma membrane#GO:0098739;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation transport#GO:0006812;transition metal ion transport#GO:0000041;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;import into cell#GO:0098657 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000004045.3|UniProtKB=F7B6W8 F7B6W8 PTHR13182:SF8 ZINC FINGER PROTEIN 622 CYTOPLASMIC 60S SUBUNIT BIOGENESIS FACTOR ZNF622 cellular component organization or biogenesis#GO:0071840;cellular component biogenesis#GO:0044085;ribosome biogenesis#GO:0042254;ribosomal large subunit biogenesis#GO:0042273;cellular process#GO:0009987;ribonucleoprotein complex biogenesis#GO:0022613 ribonucleoprotein complex#GO:1990904;preribosome#GO:0030684;protein-containing complex#GO:0032991;preribosome, large subunit precursor#GO:0030687 RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000007627.3|UniProtKB=F6WJ31 F6WJ31 LOC778553 PTHR24399:SF65 ZINC FINGER AND BTB DOMAIN-CONTAINING ZINC FINGER PROTEIN cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity#GO:0001217;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of immune system process#GO:0002682;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;regulation of cytokine production#GO:0001817;regulation of multicellular organismal process#GO:0051239;negative regulation of biosynthetic process#GO:0009890;regulation of DNA-templated transcription#GO:0006355;negative regulation of metabolic process#GO:0009892;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 CIOIN|Ensembl=ENSCING00000003121.3|UniProtKB=F6R6G1 F6R6G1 PTHR11675:SF101 N-ACETYLGALACTOSAMINYLTRANSFERASE POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE 5 transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;UDP-glycosyltransferase activity#GO:0008194 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;protein O-linked glycosylation#GO:0006493;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000011383.2|UniProtKB=F6XZ84 F6XZ84 LOC100186859 PTHR35836:SF1 VCBS REPEAT-CONTAINING PROTEIN VCBS REPEAT-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000024061.1|UniProtKB=H2XNC3 H2XNC3 PTHR24115:SF162 KINESIN-RELATED KINESIN-LIKE PROTEIN KIN-14E pyrophosphatase activity#GO:0016462;cytoskeletal protein binding#GO:0008092;microtubule motor activity#GO:0003777;tubulin binding#GO:0015631;ATP-dependent activity#GO:0140657;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;cytoskeletal motor activity#GO:0003774;microtubule binding#GO:0008017;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;ribonucleoside triphosphate phosphatase activity#GO:0017111;ATP hydrolysis activity#GO:0016887 microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;microtubule associated complex#GO:0005875;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 CIOIN|Ensembl=ENSCING00000006069.3|UniProtKB=F6YXI8 F6YXI8 PTHR17605:SF0 RIBOSOME BIOGENESIS PROTEIN BOP1 BLOCK OF PROLIFERATION 1 PROTEIN RIBOSOME BIOGENESIS PROTEIN BOP1 ribonucleoprotein complex binding#GO:0043021;protein-containing complex binding#GO:0044877;binding#GO:0005488 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;RNA processing#GO:0006396;gene expression#GO:0010467;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;ribosomal large subunit biogenesis#GO:0042273;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;maturation of LSU-rRNA#GO:0000470;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;preribosome, large subunit precursor#GO:0030687;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;nuclear lumen#GO:0031981;90S preribosome#GO:0030686;nuclear protein-containing complex#GO:0140513 ribosomal protein#PC00202;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000012741.2|UniProtKB=F7A9A6 F7A9A6 LOC100175906 PTHR13071:SF4 MITOCHONDRIAL 28S RIBOSOMAL PROTEIN S22 SMALL RIBOSOMAL SUBUNIT PROTEIN MS22 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;mitochondrial ribosome#GO:0005761;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;ribosomal subunit#GO:0044391;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;organellar ribosome#GO:0000313;protein-containing complex#GO:0032991;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;small ribosomal subunit#GO:0015935;ribosome#GO:0005840;mitochondrial small ribosomal subunit#GO:0005763;mitochondrial protein-containing complex#GO:0098798 ribosomal protein#PC00202;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000015044.2|UniProtKB=F6SUX9 F6SUX9 LOC100178559 PTHR11616:SF241 SODIUM/CHLORIDE DEPENDENT TRANSPORTER SODIUM- AND CHLORIDE-DEPENDENT GLYCINE TRANSPORTER 2 inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;organic acid:sodium symporter activity#GO:0005343;organic acid transmembrane transporter activity#GO:0005342;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;organic anion transmembrane transporter activity#GO:0008514;monoatomic cation transmembrane transporter activity#GO:0008324;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;amino acid:sodium symporter activity#GO:0005283;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;metal ion transmembrane transporter activity#GO:0046873;active monoatomic ion transmembrane transporter activity#GO:0022853;amino acid transmembrane transporter activity#GO:0015171;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;organic anion transport#GO:0015711;amino acid transport#GO:0006865;organic acid transport#GO:0015849;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;amino acid import across plasma membrane#GO:0089718;carboxylic acid transmembrane transport#GO:1905039;localization#GO:0051179;organic substance transport#GO:0071702;import across plasma membrane#GO:0098739;amino acid transmembrane transport#GO:0003333;sodium ion transport#GO:0006814;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transport#GO:0006812;organic acid transmembrane transport#GO:1903825;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;import into cell#GO:0098657;sodium ion transmembrane transport#GO:0035725 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 primary active transporter#PC00068;transporter#PC00227 CIOIN|Ensembl=ENSCING00000000234.3|UniProtKB=F6T336 F6T336 PTHR24229:SF109 NEUROPEPTIDES RECEPTOR SOMATOSTATIN RECEPTOR TYPE 2-LIKE neuropeptide binding#GO:0042923;signaling receptor activity#GO:0038023;binding#GO:0005488;peptide binding#GO:0042277;amide binding#GO:0033218;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;neuropeptide signaling pathway#GO:0007218;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;neuron projection#GO:0043005;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 CIOIN|Ensembl=ENSCING00000001849.3|UniProtKB=F6T7F9 F6T7F9 zf(traf_ring)-1 PTHR10131:SF151 TNF RECEPTOR ASSOCIATED FACTOR TNF RECEPTOR ASSOCIATED FACTOR (TRAF) HOMOLOG regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;regulation of canonical NF-kappaB signal transduction#GO:0043122;regulation of signaling#GO:0023051;biological regulation#GO:0065007;regulation of intracellular signal transduction#GO:1902531 receptor complex#GO:0043235;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;plasma membrane signaling receptor complex#GO:0098802;plasma membrane protein complex#GO:0098797;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000013292.2|UniProtKB=F7BLB2 F7BLB2 PTHR15706:SF2 SH3 MULTIPLE DOMAIN SH3 AND PX DOMAIN-CONTAINING PROTEIN 2A scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000023541.1|UniProtKB=F6TK09 F6TK09 LOC100175198 PTHR12675:SF6 MUSCLEBLIND-LIKE PROTEIN ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 10 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nitrogen compound metabolic process#GO:0051171;regulation of biosynthetic process#GO:0009889;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA metabolic process#GO:0051252;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 RNA splicing factor#PC00148;RNA processing factor#PC00147;RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000006135.3|UniProtKB=F6V437 F6V437 LOC100185166 PTHR15362:SF4 PHOSPHATIDYLINOSITOL SYNTHASE CDP-DIACYLGLYCEROL--INOSITOL 3-PHOSPHATIDYLTRANSFERASE transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;phospholipid biosynthetic process#GO:0008654;organophosphate biosynthetic process#GO:0090407;phosphatidylinositol biosynthetic process#GO:0006661;glycerolipid biosynthetic process#GO:0045017;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;phosphatidylinositol metabolic process#GO:0046488;glycerophospholipid metabolic process#GO:0006650;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;glycerophospholipid biosynthetic process#GO:0046474;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000009491.3|UniProtKB=F6Y9H6 F6Y9H6 LOC100179281 PTHR12899:SF3 39S RIBOSOMAL PROTEIN L18, MITOCHONDRIAL LARGE RIBOSOMAL SUBUNIT PROTEIN UL18M nucleic acid binding#GO:0003676;RNA binding#GO:0003723;rRNA binding#GO:0019843;binding#GO:0005488;organic cyclic compound binding#GO:0097159 ribosomal protein#PC00202;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000023534.1|UniProtKB=H2Y1B5 H2Y1B5 PTHR10965:SF0 60S RIBOSOMAL PROTEIN L38 LARGE RIBOSOMAL SUBUNIT PROTEIN EL38 ribosomal protein#PC00202;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000017070.2|UniProtKB=F6X1X1 F6X1X1 LOC100177003 PTHR43735:SF3 APOPTOSIS-INDUCING FACTOR 1 FERROPTOSIS SUPPRESSOR PROTEIN 1 nucleotide binding#GO:0000166;electron transfer activity#GO:0009055;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;flavin adenine dinucleotide binding#GO:0050660;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167;oxidoreductase activity#GO:0016491 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 p53 pathway#P00059>NOXA#G01572 CIOIN|Ensembl=ENSCING00000003109.3|UniProtKB=F6PHM0 F6PHM0 PTHR11830:SF3 40S RIBOSOMAL PROTEIN S3A CYLINDROMATOSIS, ISOFORM D cysteine-type peptidase activity#GO:0008234;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;cysteine-type deubiquitinase activity#GO:0004843 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;protein K63-linked deubiquitination#GO:0070536;protein modification by small protein removal#GO:0070646;protein deubiquitination#GO:0016579;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;metabolic process#GO:0008152;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202 CIOIN|Ensembl=ENSCING00000009997.3|UniProtKB=A0A1W3JSW3 A0A1W3JSW3 LOC100187068 PTHR14154:SF2 UPF0041 BRAIN PROTEIN 44-RELATED MITOCHONDRIAL PYRUVATE CARRIER 2 CIOIN|Ensembl=ENSCING00000015390.2|UniProtKB=F6YQB2 F6YQB2 LOC100180053 PTHR13063:SF10 ENOS INTERACTING PROTEIN NITRIC OXIDE SYNTHASE-INTERACTING PROTEIN membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000021800.1|UniProtKB=H2Y1S1 H2Y1S1 PTHR46290:SF1 DI-N-ACETYLCHITOBIASE DI-N-ACETYLCHITOBIASE CIOIN|Ensembl=ENSCING00000018401.1|UniProtKB=H2XY30 H2XY30 LOC100184713 PTHR23147:SF133 SERINE/ARGININE RICH SPLICING FACTOR SERINE_ARGININE-RICH SPLICING FACTOR 10 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;nuclear speck#GO:0016607;organelle#GO:0043226;nuclear body#GO:0016604;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA splicing factor#PC00148;RNA processing factor#PC00147;RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000008228.3|UniProtKB=F6R5F9 F6R5F9 PTHR46769:SF2 POLYCYSTIC KIDNEY AND HEPATIC DISEASE 1 (AUTOSOMAL RECESSIVE)-LIKE 1 FIBROCYSTIN-L ISOFORM 2 PRECURSOR-RELATED CIOIN|Ensembl=ENSCING00000002637.3|UniProtKB=F6YDR3 F6YDR3 PTHR24006:SF644 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 7 cysteine-type peptidase activity#GO:0008234;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;cysteine-type deubiquitinase activity#GO:0004843 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;regulation of protein stability#GO:0031647;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;protein modification by small protein removal#GO:0070646;protein deubiquitination#GO:0016579;biological regulation#GO:0065007;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cysteine protease#PC00081;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000001291.3|UniProtKB=F6WWC7 F6WWC7 PTHR11588:SF13 TUBULIN TUBULIN EPSILON CHAIN carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;structural molecule activity#GO:0005198;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167;structural constituent of cytoskeleton#GO:0005200 cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;microtubule-based process#GO:0007017;organelle organization#GO:0006996;microtubule cytoskeleton organization#GO:0000226;cytoskeleton organization#GO:0007010;cell cycle#GO:0007049;cellular component organization#GO:0016043;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622 tubulin#PC00228;microtubule or microtubule-binding cytoskeletal protein#PC00157 CIOIN|Ensembl=ENSCING00000020511.1|UniProtKB=H2XUS4 H2XUS4 LOC100185641 PTHR11351:SF31 ACYL-COA DESATURASE DESATURASE 1, ISOFORM A-RELATED CIOIN|Ensembl=ENSCING00000008419.3|UniProtKB=F6X2Y1 F6X2Y1 LOC100181991 PTHR46529:SF1 TRNA WYBUTOSINE-SYNTHESIZING PROTEIN 4 TRNA WYBUTOSINE-SYNTHESIZING PROTEIN 4 tRNA methyltransferase activity#GO:0008175;catalytic activity, acting on RNA#GO:0140098;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;RNA methyltransferase activity#GO:0008173 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;carbohydrate derivative metabolic process#GO:1901135;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;RNA modification#GO:0009451;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;tRNA modification#GO:0006400;ncRNA metabolic process#GO:0034660;tRNA methylation#GO:0030488;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nucleic acid metabolic process#GO:0090304;methylation#GO:0032259;macromolecule methylation#GO:0043414;RNA methylation#GO:0001510;glycosyl compound metabolic process#GO:1901657 RNA processing factor#PC00147;RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000005316.3|UniProtKB=F7B684 F7B684 PTHR43107:SF15 LONG-CHAIN FATTY ACID TRANSPORT PROTEIN FATTY ACID TRANSPORT PROTEIN 3, ISOFORM A long-chain fatty acid-CoA ligase activity#GO:0004467;ligase activity#GO:0016874;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;ATP-dependent activity#GO:0140657;organic acid transmembrane transporter activity#GO:0005342;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877;monocarboxylic acid transmembrane transporter activity#GO:0008028;organic anion transmembrane transporter activity#GO:0008514;lipid transporter activity#GO:0005319;transporter activity#GO:0005215 long-chain fatty acid metabolic process#GO:0001676;oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;monocarboxylic acid transport#GO:0015718;macromolecule localization#GO:0033036;organic anion transport#GO:0015711;organic acid transport#GO:0015849;fatty acid transport#GO:0015908;transport#GO:0006810;carboxylic acid transport#GO:0046942;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;lipid transport#GO:0006869;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;localization#GO:0051179;organic substance transport#GO:0071702;fatty acid metabolic process#GO:0006631;establishment of localization#GO:0051234;lipid localization#GO:0010876;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;import into cell#GO:0098657;long-chain fatty acid transport#GO:0015909;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000004706.3|UniProtKB=F6QNA6 F6QNA6 zf(an1)-3 PTHR46728:SF1 AN1-TYPE ZINC FINGER PROTEIN 4 AN1-TYPE ZINC FINGER PROTEIN 4 CIOIN|Ensembl=ENSCING00000008833.3|UniProtKB=F7B0J2 F7B0J2 LOC100180348 PTHR12767:SF9 BCL7 RELATED BCL7-LIKE CIOIN|Ensembl=ENSCING00000007638.3|UniProtKB=F6WIL0 F6WIL0 PTHR11576:SF22 ZONA PELLUCIDA SPERM-BINDING PROTEIN 3 ONCOPROTEIN INDUCED TRANSCRIPT 3 CIOIN|Ensembl=ENSCING00000013250.2|UniProtKB=F6XKL3 F6XKL3 PTHR43975:SF2 ZGC:101858 EG:BACR7A4.14 PROTEIN-RELATED CIOIN|Ensembl=ENSCING00000003662.3|UniProtKB=F7AWS8 F7AWS8 LOC100186387 PTHR11132:SF255 SOLUTE CARRIER FAMILY 35 GDP-FUCOSE TRANSPORTER 1 secondary active transmembrane transporter activity#GO:0015291;antiporter activity#GO:0015297;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 localization#GO:0051179;cellular process#GO:0009987;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000002877.3|UniProtKB=F6T0V1 F6T0V1 LOC100182202 PTHR11360:SF284 MONOCARBOXYLATE TRANSPORTER EG:103B4.3 PROTEIN-RELATED transporter#PC00227 CIOIN|Ensembl=ENSCING00000003704.2|UniProtKB=F6XHS1 F6XHS1 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE SSU-1 sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824 cellular metabolic process#GO:0044237;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000019897.1|UniProtKB=H2Y145 H2Y145 PTHR45712:SF22 AGAP008170-PA INSULIN-LIKE GROWTH FACTOR-BINDING PROTEIN COMPLEX ACID LABILE SUBUNIT CIOIN|Ensembl=ENSCING00000007281.3|UniProtKB=F6SUU2 F6SUU2 PTHR13723:SF278 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE ADAM METALLOPEPTIDASE WITH THROMBOSPONDIN TYPE 1 MOTIF A, ISOFORM B hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular component organization or biogenesis#GO:0071840;extracellular structure organization#GO:0043062;external encapsulating structure organization#GO:0045229;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;cellular component organization#GO:0016043;cellular process#GO:0009987;protein metabolic process#GO:0019538;extracellular matrix organization#GO:0030198;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944 metalloprotease#PC00153;protease#PC00190 CIOIN|Ensembl=ENSCING00000022513.1|UniProtKB=H2XYR3 H2XYR3 PTHR21349:SF0 50S RIBOSOMAL PROTEIN L21 LARGE RIBOSOMAL SUBUNIT PROTEIN BL21M structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 ribosomal protein#PC00202;translational protein#PC00263 Methylcitrate cycle#P02754>Aconitase#P03028 CIOIN|Ensembl=ENSCING00000004383.3|UniProtKB=H2Y048 H2Y048 LOC100186137 PTHR11963:SF48 LEUCINE AMINOPEPTIDASE-RELATED DIPEPTIDASE B, ISOFORM A hydrolase activity#GO:0016787;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 metalloprotease#PC00153;protease#PC00190 CIOIN|Ensembl=ENSCING00000006831.3|UniProtKB=F7AZV0 F7AZV0 PTHR43416:SF5 DIHYDROLIPOYLLYSINE-RESIDUE SUCCINYLTRANSFERASE COMPONENT OF 2-OXOGLUTARATE DEHYDROGENASE COMPLEX, MITOCHONDRIAL-RELATED DIHYDROLIPOYLLYSINE-RESIDUE SUCCINYLTRANSFERASE COMPONENT OF 2-OXOGLUTARATE DEHYDROGENASE COMPLEX, MITOCHONDRIAL transferase activity#GO:0016740;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 aerobic respiration#GO:0009060;cellular respiration#GO:0045333;generation of precursor metabolites and energy#GO:0006091;cellular metabolic process#GO:0044237;cellular process#GO:0009987;tricarboxylic acid cycle#GO:0006099;energy derivation by oxidation of organic compounds#GO:0015980;primary metabolic process#GO:0044238;metabolic process#GO:0008152 transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000009653.3|UniProtKB=F6WUV8 F6WUV8 LOC100181310 PTHR16146:SF46 INTELECTIN INTELECTIN-1A-RELATED CIOIN|Ensembl=ENSCING00000006540.3|UniProtKB=F6RQ16 F6RQ16 LOC100183583 PTHR14269:SF4 CDP-DIACYLGLYCEROL--GLYCEROL-3-PHOSPHATE 3-PHOSPHATIDYLTRANSFERASE-RELATED CAT EYE SYNDROME CRITICAL REGION PROTEIN 5 lipid metabolic process#GO:0006629;phospholipid biosynthetic process#GO:0008654;organophosphate biosynthetic process#GO:0090407;glycerolipid biosynthetic process#GO:0045017;cellular metabolic process#GO:0044237;glycerophospholipid metabolic process#GO:0006650;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;phospholipid metabolic process#GO:0006644;lipid biosynthetic process#GO:0008610;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;primary metabolic process#GO:0044238;glycerolipid metabolic process#GO:0046486;glycerophospholipid biosynthetic process#GO:0046474;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000004519.3|UniProtKB=F7ASI0 F7ASI0 LOC100175110 PTHR11009:SF1 DER1-LIKE PROTEIN, DERLIN DERLIN-1 ribonucleoprotein complex binding#GO:0043021;protein-containing complex binding#GO:0044877;binding#GO:0005488 signal transduction#GO:0007165;endoplasmic reticulum unfolded protein response#GO:0030968;protein catabolic process#GO:0030163;organonitrogen compound catabolic process#GO:1901565;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;response to unfolded protein#GO:0006986;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;protein metabolic process#GO:0019538;signaling#GO:0023052;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;response to organic substance#GO:0010033;macromolecule catabolic process#GO:0009057;cellular response to stimulus#GO:0051716;response to endoplasmic reticulum stress#GO:0034976;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;ERAD pathway#GO:0036503;cell communication#GO:0007154;response to organonitrogen compound#GO:0010243;cellular process#GO:0009987;cellular response to topologically incorrect protein#GO:0035967;primary metabolic process#GO:0044238;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;response to topologically incorrect protein#GO:0035966;cellular response to unfolded protein#GO:0034620;biological regulation#GO:0065007;cellular response to stress#GO:0033554 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 primary active transporter#PC00068;transporter#PC00227 CIOIN|Ensembl=ENSCING00000000713.3|UniProtKB=Q1RLF7 Q1RLF7 Ci-ZF(C2H2)-75 PTHR24390:SF227 ZINC FINGER PROTEIN KRUEPPEL HOMOLOG 1-RELATED sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 CIOIN|Ensembl=ENSCING00000013134.2|UniProtKB=F6ZH66 F6ZH66 PTHR12276:SF45 EPSIN/ENT-RELATED CLATHRIN INTERACTOR 1 protein binding#GO:0005515;lipid binding#GO:0008289;clathrin binding#GO:0030276;phospholipid binding#GO:0005543;binding#GO:0005488 localization#GO:0051179;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization#GO:0051234;import into cell#GO:0098657;transport#GO:0006810;endocytosis#GO:0006897 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;clathrin vesicle coat#GO:0030125;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;coated vesicle#GO:0030135;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;vesicle coat#GO:0030120;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;clathrin-coated vesicle#GO:0030136;endomembrane system#GO:0012505;membrane coat#GO:0030117;coated vesicle membrane#GO:0030662;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;coated membrane#GO:0048475;cytoplasmic vesicle membrane#GO:0030659;plasma membrane#GO:0005886 membrane trafficking regulatory protein#PC00151 CIOIN|Ensembl=ENSCING00000014278.2|UniProtKB=F6WP45 F6WP45 LOC100183082 PTHR10504:SF131 BACTERICIDAL PERMEABILITY-INCREASING BPI PROTEIN-RELATED BPI2 DOMAIN-CONTAINING PROTEIN defense/immunity protein#PC00090 CIOIN|Ensembl=ENSCING00000023180.1|UniProtKB=H2Y2M6 H2Y2M6 PTHR13174:SF3 D-GLUCURONYL C5-EPIMERASE D-GLUCURONYL C5-EPIMERASE racemase and epimerase activity, acting on carbohydrates and derivatives#GO:0016857;isomerase activity#GO:0016853;catalytic activity#GO:0003824 glycoprotein biosynthetic process#GO:0009101;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;sulfur compound metabolic process#GO:0006790;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;proteoglycan metabolic process#GO:0006029;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;proteoglycan biosynthetic process#GO:0030166;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 isomerase#PC00135;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000005606.3|UniProtKB=H2XSP6 H2XSP6 LOC100177688 PTHR35970:SF1 SODIUM CHANNEL AND CLATHRIN LINKER 1 SODIUM CHANNEL AND CLATHRIN LINKER 1 organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cell projection organization#GO:0030030;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;centriole#GO:0005814;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000013296.2|UniProtKB=F7BL82 F7BL82 PTHR23503:SF132 SOLUTE CARRIER FAMILY 2 SOLUTE CARRIER FAMILY 2, FACILITATED GLUCOSE TRANSPORTER MEMBER 5-LIKE transmembrane transporter activity#GO:0022857;sugar transmembrane transporter activity#GO:0051119;transporter activity#GO:0005215;carbohydrate transmembrane transporter activity#GO:0015144 localization#GO:0051179;organic substance transport#GO:0071702;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;organic anion transport#GO:0015711;transport#GO:0006810;vitamin transport#GO:0051180;glucose transmembrane transport#GO:1904659;cellular process#GO:0009987;carbohydrate transmembrane transport#GO:0034219;carbohydrate transport#GO:0008643 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000007190.3|UniProtKB=F6YSB9 F6YSB9 PTHR11224:SF10 MAKORIN-RELATED IP09428P-RELATED transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000021033.1|UniProtKB=H2XXY3 H2XXY3 PTHR12472:SF0 RAB3-GAP REGULATORY DOMAIN RAB3 GTPASE-ACTIVATING PROTEIN NON-CATALYTIC SUBUNIT biological regulation#GO:0065007;regulation of hydrolase activity#GO:0051336;regulation of catalytic activity#GO:0050790;regulation of GTPase activity#GO:0043087;regulation of molecular function#GO:0065009 G-protein modulator#PC00022;protein-binding activity modulator#PC00095 CIOIN|Ensembl=ENSCING00000019712.1|UniProtKB=F6Y7J8 F6Y7J8 LOC100178752 PTHR11723:SF17 DNA-BINDING PROTEIN INHIBITOR PROTEIN EXTRA-MACROCHAETAE negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;rhythmic process#GO:0048511;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;regulation of biosynthetic process#GO:0009889;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;cellular developmental process#GO:0048869;circadian rhythm#GO:0007623;negative regulation of biosynthetic process#GO:0009890;regulation of DNA-templated transcription#GO:0006355;negative regulation of metabolic process#GO:0009892;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;circadian regulation of gene expression#GO:0032922;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218 CIOIN|Ensembl=ENSCING00000003660.3|UniProtKB=F7ADN1 F7ADN1 PTHR18937:SF172 STRUCTURAL MAINTENANCE OF CHROMOSOMES SMC FAMILY MEMBER STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN nuclear chromosome segregation#GO:0098813;sister chromatid segregation#GO:0000819;nuclear division#GO:0000280;cell cycle process#GO:0022402;chromosome condensation#GO:0030261;cellular component organization#GO:0016043;cellular process#GO:0009987;mitotic cell cycle process#GO:1903047;chromosome segregation#GO:0007059;mitotic chromosome condensation#GO:0007076;cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;chromosome organization#GO:0051276;organelle organization#GO:0006996;cell cycle#GO:0007049;mitotic nuclear division#GO:0140014;organelle fission#GO:0048285;mitotic sister chromatid segregation#GO:0000070 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000005141.3|UniProtKB=F6VAW2 F6VAW2 PTHR15067:SF5 E3 UBIQUITIN-PROTEIN LIGASE RNF8 E3 UBIQUITIN-PROTEIN LIGASE AMFR transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 signal transduction#GO:0007165;endoplasmic reticulum unfolded protein response#GO:0030968;macromolecule modification#GO:0043412;protein catabolic process#GO:0030163;organonitrogen compound catabolic process#GO:1901565;protein modification process#GO:0036211;post-translational protein modification#GO:0043687;modification-dependent macromolecule catabolic process#GO:0043632;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;response to unfolded protein#GO:0006986;proteolysis#GO:0006508;catabolic process#GO:0009056;protein polyubiquitination#GO:0000209;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;proteolysis involved in protein catabolic process#GO:0051603;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;response to organic substance#GO:0010033;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;cellular response to stimulus#GO:0051716;response to endoplasmic reticulum stress#GO:0034976;cellular response to chemical stimulus#GO:0070887;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;cellular response to organic substance#GO:0071310;protein K48-linked ubiquitination#GO:0070936;organonitrogen compound metabolic process#GO:1901564;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to topologically incorrect protein#GO:0035967;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cellular response to unfolded protein#GO:0034620;response to topologically incorrect protein#GO:0035966;biological regulation#GO:0065007;cellular response to stress#GO:0033554 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000016051.2|UniProtKB=F6W6D7 F6W6D7 zf(cchc)-11 PTHR13316:SF0 ZINC FINGER, CCHC DOMAIN CONTAINING 8 ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 8 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 ribonucleoprotein complex#GO:1990904;catalytic step 2 spliceosome#GO:0071013;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000006352.3|UniProtKB=F6RS47 F6RS47 PTHR24230:SF157 G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;neuropeptide signaling pathway#GO:0007218;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 CIOIN|Ensembl=ENSCING00000006734.3|UniProtKB=F6YLC1 F6YLC1 LOC100186199 PTHR23091:SF4 N-TERMINAL ACETYLTRANSFERASE N-TERMINAL AMINO-ACID N(ALPHA)-ACETYLTRANSFERASE NATA acetyltransferase#PC00038 CIOIN|Ensembl=ENSCING00000010618.3|UniProtKB=F7BB38 F7BB38 PTHR24300:SF397 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 2U1 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;tetrapyrrole binding#GO:0046906;steroid hydroxylase activity#GO:0008395;oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497;heme binding#GO:0020037 response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;response to chemical#GO:0042221;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 oxygenase#PC00177;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000017501.2|UniProtKB=F6T1D8 F6T1D8 PTHR31395:SF25 SHISA ABLIM_ANCHOR DOMAIN-CONTAINING PROTEIN scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000019169.1|UniProtKB=H2XVM0 H2XVM0 LOC100181195 PTHR13976:SF25 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN-RELATED RNA-BINDING PROTEIN FUSILLI nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nitrogen compound metabolic process#GO:0051171;regulation of biosynthetic process#GO:0009889;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA splicing factor#PC00148;RNA processing factor#PC00147;RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000008463.3|UniProtKB=F6TR93 F6TR93 PTHR10201:SF331 MATRIX METALLOPROTEINASE MATRIX METALLOPROTEINASE-14-LIKE ISOFORM X1 hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular component organization or biogenesis#GO:0071840;extracellular structure organization#GO:0043062;external encapsulating structure organization#GO:0045229;catabolic process#GO:0009056;cellular component organization#GO:0016043;cellular process#GO:0009987;extracellular matrix organization#GO:0030198;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000013638.2|UniProtKB=F6UCB5 F6UCB5 LOC100177071 PTHR12147:SF26 METALLOPEPTIDASE M28 FAMILY MEMBER PEPTIDASE M28 DOMAIN-CONTAINING PROTEIN macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;metabolic process#GO:0008152;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704 metalloprotease#PC00153;protease#PC00190 CIOIN|Ensembl=ENSCING00000024510.1|UniProtKB=H2XTV7 H2XTV7 PTHR10083:SF373 KUNITZ-TYPE PROTEASE INHIBITOR-RELATED SERINE PEPTIDASE INHIBITOR, KUNITZ TYPE, 2 peptidase inhibitor activity#GO:0030414;molecular function regulator activity#GO:0098772;serine-type endopeptidase inhibitor activity#GO:0004867;peptidase regulator activity#GO:0061134;enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;endopeptidase regulator activity#GO:0061135;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191;protein-binding activity modulator#PC00095 CIOIN|Ensembl=ENSCING00000008908.3|UniProtKB=F6QBC9 F6QBC9 irf-like-7 PTHR11949:SF53 INTERFERON REGULATORY FACTOR IRF TRYPTOPHAN PENTAD REPEAT DOMAIN-CONTAINING PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 CIOIN|Ensembl=ENSCING00000018302.1|UniProtKB=H2XS33 H2XS33 PTHR12297:SF3 HYPOXIA-INDUCBILE GENE 1 HIG1 -RELATED HIG1 DOMAIN FAMILY MEMBER 1A scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000023766.1|UniProtKB=H2XL39 H2XL39 LOC100176317 PTHR11683:SF12 MYELIN PROTEOLIPID M6, ISOFORM F cellular developmental process#GO:0048869;neurogenesis#GO:0022008;cell projection organization#GO:0030030;multicellular organism development#GO:0007275;developmental process#GO:0032502;cellular component organization#GO:0016043;cellular process#GO:0009987;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;system development#GO:0048731;neuron projection development#GO:0031175;cell differentiation#GO:0030154;anatomical structure development#GO:0048856;neuron differentiation#GO:0030182;neuron development#GO:0048666;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 myelin protein#PC00161 CIOIN|Ensembl=ENSCING00000001398.3|UniProtKB=F6ZBE4 F6ZBE4 PTHR24073:SF128 DRAB5-RELATED RAB-LIKE PROTEIN 3 GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824 localization#GO:0051179;organic substance transport#GO:0071702;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;transport#GO:0006810;protein transport#GO:0015031;nitrogen compound transport#GO:0071705;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104 cellular anatomical entity#GO:0110165;endomembrane system#GO:0012505 small GTPase#PC00208;G-protein#PC00020 CIOIN|Ensembl=ENSCING00000014704.2|UniProtKB=F6ZC68 F6ZC68 PTHR24300:SF397 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 2U1 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;tetrapyrrole binding#GO:0046906;steroid hydroxylase activity#GO:0008395;oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497;heme binding#GO:0020037 response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;response to chemical#GO:0042221;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 oxygenase#PC00177;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000006576.4|UniProtKB=F6R1A2 F6R1A2 LOC100175958 PTHR12965:SF0 VACUOLAR PROTEIN SORTING 54 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 54 syntaxin binding#GO:0019905;protein binding#GO:0005515;binding#GO:0005488;SNARE binding#GO:0000149 localization#GO:0051179;endosomal transport#GO:0016197;cellular localization#GO:0051641;Golgi to vacuole transport#GO:0006896;establishment of localization#GO:0051234;vacuolar transport#GO:0007034;post-Golgi vesicle-mediated transport#GO:0006892;transport#GO:0006810;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987;cytosolic transport#GO:0016482;retrograde transport, endosome to Golgi#GO:0042147 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular vesicle#GO:0097708;vesicle tethering complex#GO:0099023;Golgi apparatus#GO:0005794;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150 CIOIN|Ensembl=ENSCING00000007769.3|UniProtKB=A0A1W3JJQ5 A0A1W3JJQ5 LOC100183094 PTHR47981:SF20 RAB FAMILY RAS-RELATED PROTEIN RAB-7A small GTPase#PC00208;G-protein#PC00020 CIOIN|Ensembl=ENSCING00000007967.3|UniProtKB=F6Z7N3 F6Z7N3 PTHR46003:SF1 HOST CELL FACTOR HOST CELL FACTOR transcription coactivator activity#GO:0003713;molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;protein-macromolecule adaptor activity#GO:0030674 protein-DNA complex organization#GO:0071824;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;cellular component organization#GO:0016043;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;protein-containing complex organization#GO:0043933;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;chromatin remodeling#GO:0006338;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;histone methyltransferase complex#GO:0035097;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;methyltransferase complex#GO:0034708;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 CIOIN|Ensembl=ENSCING00000008473.3|UniProtKB=F6TQG1 F6TQG1 LOC100175025 PTHR10920:SF12 RIBOSOMAL RNA METHYLTRANSFERASE TRNA (CYTIDINE(32)_GUANOSINE(34)-2'-O)-METHYLTRANSFERASE-RELATED tRNA methyltransferase activity#GO:0008175;catalytic activity, acting on RNA#GO:0140098;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;RNA methyltransferase activity#GO:0008173 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;peptide metabolic process#GO:0006518;RNA modification#GO:0009451;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;tRNA modification#GO:0006400;translation#GO:0006412;ncRNA metabolic process#GO:0034660;tRNA methylation#GO:0030488;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cytoplasmic translation#GO:0002181;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nucleic acid metabolic process#GO:0090304;macromolecule methylation#GO:0043414;methylation#GO:0032259;RNA methylation#GO:0001510 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 RNA methyltransferase#PC00033 CIOIN|Ensembl=ENSCING00000015091.2|UniProtKB=F6TQ55 F6TQ55 PTHR31938:SF4 NUCLEAR SPECKLE SPLICING REGULATORY PROTEIN 1 NUCLEAR SPECKLE SPLICING REGULATORY PROTEIN 1 CIOIN|Ensembl=ENSCING00000010421.3|UniProtKB=F6R2E4 F6R2E4 LOC100179821 PTHR33769:SF2 TESTIS-EXPRESSED PROTEIN 26 ISOFORM X3 TESTIS-EXPRESSED PROTEIN 26 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000012925.2|UniProtKB=F6RM26 F6RM26 PTHR15071:SF29 MANNOSE-6-PHOSPHATE RECEPTOR FAMILY MEMBER CATION-DEPENDENT MANNOSE-6-PHOSPHATE RECEPTOR cellular localization#GO:0051641;establishment of protein localization to vacuole#GO:0072666;macromolecule localization#GO:0033036;protein targeting to vacuole#GO:0006623;vacuolar transport#GO:0007034;transport#GO:0006810;protein localization to vacuole#GO:0072665;protein targeting#GO:0006605;nitrogen compound transport#GO:0071705;establishment of protein localization to organelle#GO:0072594;cellular process#GO:0009987;protein targeting to lysosome#GO:0006622;lysosomal transport#GO:0007041;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;organic substance transport#GO:0071702;protein localization to lysosome#GO:0061462;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;protein localization to organelle#GO:0033365 cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;Golgi apparatus subcompartment#GO:0098791;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150 CIOIN|Ensembl=ENSCING00000008892.3|UniProtKB=F6QX43 F6QX43 LOC100179146 PTHR16146:SF46 INTELECTIN INTELECTIN-1A-RELATED CIOIN|Ensembl=ENSCING00000001251.3|UniProtKB=F7AEN4 F7AEN4 nodal PTHR11848:SF302 TGF-BETA FAMILY TGF-BETA FAMILY PROFILE DOMAIN-CONTAINING PROTEIN molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;cytokine activity#GO:0005125;protein binding#GO:0005515;signaling receptor binding#GO:0005102 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 CIOIN|Ensembl=ENSCING00000004811.3|UniProtKB=F6R9V2 F6R9V2 PTHR23048:SF49 MYOSIN LIGHT CHAIN 1, 3 FI08416P-RELATED intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;myosin complex#GO:0016459;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 CIOIN|Ensembl=ENSCING00000025101.1|UniProtKB=F6WMT5 F6WMT5 PTHR10799:SF879 SNF2/RAD54 HELICASE FAMILY CHROMATIN-REMODELING COMPLEX ATPASE CHAIN ISWI ATP-dependent activity, acting on DNA#GO:0008094;nucleic acid binding#GO:0003676;ATP-dependent activity#GO:0140657;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on DNA#GO:0140097 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-DNA complex#GO:0032993;chromosome#GO:0005694;chromatin#GO:0000785;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA helicase#PC00011;DNA metabolism protein#PC00009 Wnt signaling pathway#P00057>SWI/SNF#P01435 CIOIN|Ensembl=ENSCING00000020006.1|UniProtKB=H2XJM1 H2XJM1 PTHR24300:SF397 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 2U1 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;tetrapyrrole binding#GO:0046906;steroid hydroxylase activity#GO:0008395;oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497;heme binding#GO:0020037 response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;response to chemical#GO:0042221;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 oxygenase#PC00177;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000006420.3|UniProtKB=F6PQG2 F6PQG2 gla3 PTHR24033:SF224 EGF-LIKE DOMAIN-CONTAINING PROTEIN C-TYPE LECTIN CIOIN|Ensembl=ENSCING00000005044.3|UniProtKB=F6SM47 F6SM47 LOC100178567 PTHR10830:SF0 DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE 48 KDA SUBUNIT DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE 48 KDA SUBUNIT glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein N-linked glycosylation#GO:0006487;protein metabolic process#GO:0019538;protein N-linked glycosylation via asparagine#GO:0018279;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 membrane protein complex#GO:0098796;endoplasmic reticulum protein-containing complex#GO:0140534;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endoplasmic reticulum subcompartment#GO:0098827;oligosaccharyltransferase complex#GO:0008250;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 glycosyltransferase#PC00111 CIOIN|Ensembl=ENSCING00000009283.3|UniProtKB=F7BA39 F7BA39 PTHR11216:SF176 EH DOMAIN EPIDERMAL GROWTH FACTOR RECEPTOR PATHWAY SUBSTRATE CLONE 15, ISOFORM A localization#GO:0051179;endosomal transport#GO:0016197;cellular localization#GO:0051641;establishment of localization#GO:0051234;transport#GO:0006810;endocytosis#GO:0006897;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;cellular process#GO:0009987;import into cell#GO:0098657 cytoplasm#GO:0005737;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;membrane coat#GO:0030117;plasma membrane protein complex#GO:0098797;coated membrane#GO:0048475;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;clathrin-coated pit#GO:0005905;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 membrane traffic protein#PC00150 CIOIN|Ensembl=ENSCING00000005779.3|UniProtKB=F6RSR2 F6RSR2 LOC100182171 PTHR17250:SF0 NEGATIVE ELONGATION FACTOR E NEGATIVE ELONGATION FACTOR E regulation of DNA-templated transcription elongation#GO:0032784;regulation of transcription elongation by RNA polymerase II#GO:0034243;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of biosynthetic process#GO:0009890;negative regulation of RNA metabolic process#GO:0051253;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of metabolic process#GO:0009892;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;transcription elongation factor complex#GO:0008023;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000008879.3|UniProtKB=F6QXJ4 F6QXJ4 LOC113474059 PTHR31019:SF1 SMALL INTEGRAL MEMBRANE PROTEIN 14 SMALL INTEGRAL MEMBRANE PROTEIN 14 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000015780.2|UniProtKB=F6UQQ5 F6UQQ5 PTHR43788:SF16 DNA2/NAM7 HELICASE FAMILY MEMBER HELICASE WITH ZINC FINGER 2 catalytic activity, acting on a nucleic acid#GO:0140640;ATP-dependent activity, acting on DNA#GO:0008094;DNA helicase activity#GO:0003678;catalytic activity, acting on DNA#GO:0140097;helicase activity#GO:0004386;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824 DNA metabolism protein#PC00009 CIOIN|Ensembl=ENSCING00000003108.3|UniProtKB=F6PHN6 F6PHN6 LOC100182774 PTHR10281:SF4 MEMBRANE-ASSOCIATED PROGESTERONE RECEPTOR COMPONENT-RELATED NEUFERRICIN cellular anatomical entity#GO:0110165;membrane#GO:0016020;endomembrane system#GO:0012505 transmembrane signal receptor#PC00197 CIOIN|Ensembl=ENSCING00000012983.2|UniProtKB=F6RAU0 F6RAU0 LOC100178009 PTHR24276:SF91 POLYSERASE-RELATED AT26814P-RELATED hydrolase activity#GO:0016787;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171 serine protease#PC00203;protease#PC00190 CIOIN|Ensembl=ENSCING00000003874.3|UniProtKB=H2XRS2 H2XRS2 PTHR10117:SF54 TRANSIENT RECEPTOR POTENTIAL CHANNEL TRANSIENT RECEPTOR POTENTIAL-GAMMA PROTEIN calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;calcium channel activity#GO:0005262;small molecule binding#GO:0036094;binding#GO:0005488;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;anion binding#GO:0043168;ion binding#GO:0043167;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;alcohol binding#GO:0043178 inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;calcium ion transmembrane transport#GO:0070588;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;homeostatic process#GO:0042592;monoatomic cation homeostasis#GO:0055080;inorganic ion transmembrane transport#GO:0098660;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;cellular process#GO:0009987;regulation of cytosolic calcium ion concentration#GO:0051480;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;calcium ion transport#GO:0006816;monoatomic ion homeostasis#GO:0050801;localization#GO:0051179;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation transport#GO:0006812;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;cation channel complex#GO:0034703;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 Alzheimer disease-presenilin pathway#P00004>Capacitative calcium channels#P00124 CIOIN|Ensembl=ENSCING00000020235.1|UniProtKB=H2Y3S7 H2Y3S7 PTHR23288:SF17 OCCLUDIN AND RNA POLYMERASE II ELONGATION FACTOR ELL RNA POLYMERASE II ELONGATION FACTOR ELL sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690 regulation of transcription elongation by RNA polymerase II#GO:0034243;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;positive regulation of DNA-templated transcription, elongation#GO:0032786;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;ncRNA metabolic process#GO:0034660;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;DNA-templated transcription#GO:0006351;positive regulation of transcription elongation by RNA polymerase II#GO:0032968;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;regulation of DNA-templated transcription elongation#GO:0032784;heterocycle metabolic process#GO:0046483;snRNA metabolic process#GO:0016073;snRNA transcription by RNA polymerase II#GO:0042795;macromolecule biosynthetic process#GO:0009059;regulation of DNA-templated transcription#GO:0006355;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;positive regulation of cellular biosynthetic process#GO:0031328;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;ncRNA transcription#GO:0098781;biological regulation#GO:0065007;positive regulation of RNA metabolic process#GO:0051254;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;transcription elongation factor complex#GO:0008023;intracellular anatomical structure#GO:0005622 general transcription factor#PC00259 CIOIN|Ensembl=ENSCING00000011810.2|UniProtKB=F6S014 F6S014 LOC100187123 PTHR23105:SF31 RIBOSOMAL PROTEIN L7AE FAMILY MEMBER RIBOSOMAL L1 DOMAIN-CONTAINING PROTEIN 1 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;maturation of SSU-rRNA#GO:0030490;ribosomal small subunit biogenesis#GO:0042274;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202 CIOIN|Ensembl=ENSCING00000005654.3|UniProtKB=F6Y1W8 F6Y1W8 PTHR46652:SF3 LEUCINE-RICH REPEAT AND IQ DOMAIN-CONTAINING PROTEIN 1-RELATED LEUCINE-RICH REPEAT-CONTAINING PROTEIN 9 CIOIN|Ensembl=ENSCING00000017986.1|UniProtKB=H2XME0 H2XME0 PTHR23167:SF69 CALPONIN HOMOLOGY DOMAIN-CONTAINING PROTEIN DDB_G0272472-RELATED FI18193P1 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000021742.1|UniProtKB=F7BGU9 F7BGU9 PTHR11453:SF47 ANION EXCHANGE PROTEIN ANION EXCHANGE PROTEIN transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 localization#GO:0051179;organic substance transport#GO:0071702;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;organic anion transport#GO:0015711;transport#GO:0006810;homeostatic process#GO:0042592;chemical homeostasis#GO:0048878;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000000536.3|UniProtKB=F6ULY5 F6ULY5 PTHR46652:SF3 LEUCINE-RICH REPEAT AND IQ DOMAIN-CONTAINING PROTEIN 1-RELATED LEUCINE-RICH REPEAT-CONTAINING PROTEIN 9 CIOIN|Ensembl=ENSCING00000014482.2|UniProtKB=F6YM31 F6YM31 PTHR10367:SF9 MRNA-CAPPING ENZYME DUAL-SPECIFICITY PHOSPHATASE 11 (RNA_RNP COMPLEX 1-INTERACTING) catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;hydrolase activity#GO:0016787;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphoric ester hydrolase activity#GO:0042578 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;mRNA processing#GO:0006397;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 RNA processing factor#PC00147;RNA metabolism protein#PC00031;mRNA capping factor#PC00145 CIOIN|Ensembl=ENSCING00000023798.1|UniProtKB=H2XS07 H2XS07 PTHR24343:SF348 SERINE/THREONINE KINASE AT25266P transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;phosphorylation#GO:0016310;protein phosphorylation#GO:0006468;cellular process#GO:0009987;protein metabolic process#GO:0019538;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000007566.3|UniProtKB=F7BD35 F7BD35 LOC100186785 PTHR22603:SF93 CHOLINE/ETHANOALAMINE KINASE RE24176P transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301 lipid metabolic process#GO:0006629;phospholipid biosynthetic process#GO:0008654;organophosphate biosynthetic process#GO:0090407;glycerolipid biosynthetic process#GO:0045017;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;glycerophospholipid metabolic process#GO:0006650;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;phosphatidylcholine biosynthetic process#GO:0006656;glycerolipid metabolic process#GO:0046486;nitrogen compound metabolic process#GO:0006807;glycerophospholipid biosynthetic process#GO:0046474;organophosphate metabolic process#GO:0019637;phosphatidylcholine metabolic process#GO:0046470;cellular lipid metabolic process#GO:0044255;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 kinase#PC00137 CIOIN|Ensembl=ENSCING00000014085.2|UniProtKB=F6U005 F6U005 PTHR11771:SF153 LIPOXYGENASE LIPOXYGENASE DOMAIN-CONTAINING PROTEIN oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;dioxygenase activity#GO:0051213 lipid metabolic process#GO:0006629;lipid oxidation#GO:0034440;cellular metabolic process#GO:0044237;lipid modification#GO:0030258;cellular lipid metabolic process#GO:0044255;cellular process#GO:0009987;metabolic process#GO:0008152;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704 oxygenase#PC00177;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000019664.1|UniProtKB=H2XWZ5 H2XWZ5 PTHR12129:SF17 HEPARAN SULFATE 2-O-SULFOTRANSFERASE HEPARAN SULFATE 2-O-SULFOTRANSFERASE 1 sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824 glycoprotein biosynthetic process#GO:0009101;carbohydrate biosynthetic process#GO:0016051;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;sulfur compound metabolic process#GO:0006790;polysaccharide biosynthetic process#GO:0000271;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;proteoglycan metabolic process#GO:0006029;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;polysaccharide metabolic process#GO:0005976;proteoglycan biosynthetic process#GO:0030166;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;carbohydrate metabolic process#GO:0005975;glycoprotein metabolic process#GO:0009100;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000010134.3|UniProtKB=F6PIA1 F6PIA1 PTHR24418:SF447 TYROSINE-PROTEIN KINASE TYROSINE PROTEIN-KINASE SRC-1 protein tyrosine kinase activity#GO:0004713;non-membrane spanning protein tyrosine kinase activity#GO:0004715;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein binding#GO:0005515;catalytic activity, acting on a protein#GO:0140096;signaling receptor binding#GO:0005102;kinase activity#GO:0016301;protein kinase activity#GO:0004672 response to external biotic stimulus#GO:0043207;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;immune response#GO:0006955;developmental process#GO:0032502;cell communication#GO:0007154;cellular process#GO:0009987;defense response to symbiont#GO:0140546;regulation of biological process#GO:0050789;immune system process#GO:0002376;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;cell differentiation#GO:0030154;enzyme-linked receptor protein signaling pathway#GO:0007167;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological process involved in interspecies interaction between organisms#GO:0044419;biological regulation#GO:0065007;innate immune response#GO:0045087;defense response#GO:0006952;signaling#GO:0023052;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169 non-receptor tyrosine protein kinase#PC00168 Parkinson disease#P00049>Src kinase#P01230;Integrin signalling pathway#P00034>Src#P00940 CIOIN|Ensembl=ENSCING00000022996.1|UniProtKB=H2XKJ0 H2XKJ0 LOC100182357 PTHR23404:SF3 MOLYBDOPTERIN SYNTHASE RELATED MAP3K12-BINDING INHIBITORY PROTEIN 1 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000002122.3|UniProtKB=F6RVB8 F6RVB8 LOC100184303 PTHR21531:SF0 LOW-TEMPERATURE VIABILITY PROTEIN LTV1-RELATED PROTEIN LTV1 HOMOLOG cellular component biogenesis#GO:0044085;ribosomal subunit export from nucleus#GO:0000054;cellular localization#GO:0051641;organelle localization#GO:0051640;transport#GO:0006810;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;nuclear export#GO:0051168;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;ribonucleoprotein complex biogenesis#GO:0022613;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;ribosome biogenesis#GO:0042254;nuclear transport#GO:0051169;establishment of organelle localization#GO:0051656;ribosomal small subunit biogenesis#GO:0042274;protein-containing complex localization#GO:0031503 cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;preribosome, small subunit precursor#GO:0030688;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;preribosome#GO:0030684;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000011510.2|UniProtKB=F6WUA7 F6WUA7 PTHR43948:SF10 DNAJ HOMOLOG SUBFAMILY B MRJ, ISOFORM E chaperone#PC00072 CIOIN|Ensembl=ENSCING00000009087.3|UniProtKB=F6Q9K0 F6Q9K0 PTHR11946:SF109 VALYL-TRNA SYNTHETASES VALINE--TRNA LIGASE catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;ligase activity#GO:0016874;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;peptide biosynthetic process#GO:0043043;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 aminoacyl-tRNA synthetase#PC00047;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000013056.2|UniProtKB=F6T511 F6T511 LOC100179796 PTHR10426:SF88 STRICTOSIDINE SYNTHASE-RELATED ADIPOCYTE PLASMA MEMBRANE-ASSOCIATED PROTEIN HEMOMUCIN-RELATED hydrolase activity#GO:0016787;catalytic activity#GO:0003824 CIOIN|Ensembl=ENSCING00000004920.3|UniProtKB=F7AR17 F7AR17 LOC100175052 PTHR12461:SF42 HYPOXIA-INDUCIBLE FACTOR 1 ALPHA INHIBITOR-RELATED JMJC DOMAIN-CONTAINING PROTEIN protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000019148.1|UniProtKB=F6TAK8 F6TAK8 PTHR23409:SF18 RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE SMALL CHAIN RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE SUBUNIT M2 reductase#PC00198;oxidoreductase#PC00176 De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>CDP Reductase#P02915;De novo purine biosynthesis#P02738>ADP reductase#P02902;De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>UDP reductase#P02921;De novo purine biosynthesis#P02738>GDP reductase#P02909 CIOIN|Ensembl=ENSCING00000007800.3|UniProtKB=F6X3A0 F6X3A0 PTHR21664:SF1 CHRONIC MYELOGENOUS LEUKEMIA TUMOR ANTIGEN 66 NUDC DOMAIN-CONTAINING PROTEIN 1 CIOIN|Ensembl=ENSCING00000006234.3|UniProtKB=F6YCP6 F6YCP6 LOC101243211 PTHR45860:SF1 TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT ALPHA TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT ALPHA translation initiation factor#PC00224;translation factor#PC00223;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000016044.2|UniProtKB=F6W6Y0 F6W6Y0 LOC100183546 PTHR45973:SF9 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT SDS22-RELATED LEUCINE-RICH REPEAT-CONTAINING PROTEIN 46 phosphatase modulator#PC00184 CIOIN|Ensembl=ENSCING00000005498.3|UniProtKB=F7BE19 F7BE19 PTHR20920:SF5 RPE-SPONDIN SMB DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000003180.3|UniProtKB=F7ANX0 F7ANX0 PTHR23503:SF8 SOLUTE CARRIER FAMILY 2 FACILITATED GLUCOSE TRANSPORTER PROTEIN 1 transmembrane transporter activity#GO:0022857;sugar transmembrane transporter activity#GO:0051119;transporter activity#GO:0005215;carbohydrate transmembrane transporter activity#GO:0015144 localization#GO:0051179;organic substance transport#GO:0071702;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810;cellular process#GO:0009987;carbohydrate transmembrane transport#GO:0034219;carbohydrate transport#GO:0008643 cellular anatomical entity#GO:0110165;membrane#GO:0016020 secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000023472.1|UniProtKB=H2Y1T3 H2Y1T3 PTHR22906:SF52 PROPERDIN ADHESION G PROTEIN-COUPLED RECEPTOR B1 CIOIN|Ensembl=ENSCING00000018806.1|UniProtKB=H2XJL7 H2XJL7 PTHR46809:SF2 STROMAL CELL-DERIVED FACTOR 2-LIKE PROTEIN GH21273P CIOIN|Ensembl=ENSCING00000015328.2|UniProtKB=F7APG8 F7APG8 PTHR15680:SF9 RIBOSOMAL PROTEIN L19 LARGE RIBOSOMAL SUBUNIT PROTEIN BL19M structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 ribosomal protein#PC00202;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000018336.1|UniProtKB=F7BBL3 F7BBL3 PTHR15162:SF7 ASPARTOACYLASE SUCCINYLGLUTAMATE DESUCCINYLASE CIOIN|Ensembl=ENSCING00000008574.3|UniProtKB=F6X0F3 F6X0F3 LOC100181072 PTHR10623:SF6 MICROTUBULE-ASSOCIATED PROTEIN RP/EB FAMILY MEMBER EB1, ISOFORM F-RELATED cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;microtubule plus-end binding#GO:0051010;binding#GO:0005488 regulation of microtubule-based process#GO:0032886;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;macromolecule localization#GO:0033036;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;regulation of cellular component organization#GO:0051128;chromosome segregation#GO:0007059;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;regulation of microtubule cytoskeleton organization#GO:0070507;spindle assembly#GO:0051225;cytoskeleton organization#GO:0007010;spindle organization#GO:0007051;protein localization to organelle#GO:0033365;non-membrane-bounded organelle assembly#GO:0140694;cellular component assembly#GO:0022607;regulation of organelle organization#GO:0033043;cellular component organization#GO:0016043;regulation of microtubule polymerization or depolymerization#GO:0031110;cellular process#GO:0009987;protein localization#GO:0008104;organelle assembly#GO:0070925;localization#GO:0051179;protein localization to cytoskeleton#GO:0044380;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;microtubule-based process#GO:0007017;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;biological regulation#GO:0065007;cell cycle#GO:0007049 supramolecular complex#GO:0099080;spindle midzone#GO:0051233;microtubule organizing center#GO:0005815;cytoplasmic microtubule#GO:0005881;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;supramolecular fiber#GO:0099512;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;cytoskeleton#GO:0005856;microtubule plus-end#GO:0035371;spindle#GO:0005819;microtubule#GO:0005874 non-motor microtubule binding protein#PC00166 CIOIN|Ensembl=ENSCING00000004324.3|UniProtKB=F6TS86 F6TS86 PTHR22589:SF67 CARNITINE O-ACYLTRANSFERASE PEROXISOMAL CARNITINE O-OCTANOYLTRANSFERASE transferase#PC00220;acyltransferase#PC00042;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000019031.1|UniProtKB=H2XPL6 H2XPL6 PTHR46356:SF1 MITOCHONDRIAL 2-OXODICARBOXYLATE CARRIER MITOCHONDRIAL 2-OXODICARBOXYLATE CARRIER secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000003548.3|UniProtKB=F7AYB9 F7AYB9 LOC100186203 PTHR43450:SF1 ASPARTYL-TRNA SYNTHETASE ASPARTATE--TRNA LIGASE, CYTOPLASMIC catalytic activity, acting on RNA#GO:0140098;ligase activity#GO:0016874;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;catalytic activity, acting on a nucleic acid#GO:0140640 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;peptide biosynthetic process#GO:0043043;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cytosol#GO:0005829;intracellular protein-containing complex#GO:0140535;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622 aminoacyl-tRNA synthetase#PC00047;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000000321.3|UniProtKB=F6WEG7 F6WEG7 LOC100183146 PTHR12430:SF0 MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM20 TRANSLOCASE OF OUTER MITOCHONDRIAL MEMBRANE 20 signal sequence binding#GO:0005048;protein transmembrane transporter activity#GO:0008320;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277 cellular localization#GO:0051641;transmembrane transport#GO:0055085;macromolecule localization#GO:0033036;establishment of RNA localization#GO:0051236;transport#GO:0006810;protein transmembrane transport#GO:0071806;protein targeting#GO:0006605;nucleic acid transport#GO:0050657;nitrogen compound transport#GO:0071705;establishment of protein localization to organelle#GO:0072594;protein localization to mitochondrion#GO:0070585;cellular process#GO:0009987;protein transmembrane import into intracellular organelle#GO:0044743;establishment of protein localization#GO:0045184;RNA localization#GO:0006403;protein localization#GO:0008104;localization#GO:0051179;mitochondrial transport#GO:0006839;organic substance transport#GO:0071702;protein import into mitochondrial matrix#GO:0030150;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein targeting to mitochondrion#GO:0006626;establishment of protein localization to mitochondrion#GO:0072655;RNA transport#GO:0050658;nucleobase-containing compound transport#GO:0015931;protein transport#GO:0015031;protein localization to organelle#GO:0033365;mitochondrial transmembrane transport#GO:1990542 envelope#GO:0031975;bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;intracellular membrane-bounded organelle#GO:0043231;mitochondrial outer membrane#GO:0005741;mitochondrial outer membrane translocase complex#GO:0005742;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;organelle outer membrane#GO:0031968;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867;mitochondrial protein-containing complex#GO:0098798 primary active transporter#PC00068;transporter#PC00227 CIOIN|Ensembl=ENSCING00000022426.1|UniProtKB=H2XZF3 H2XZF3 PTHR13340:SF2 GATA ZINC FINGER DOMAIN-CONTAINING GATA ZINC FINGER DOMAIN-CONTAINING PROTEIN 1 cellular component organization or biogenesis#GO:0071840;chromatin organization#GO:0006325;protein-DNA complex organization#GO:0071824;cellular component organization#GO:0016043;cellular process#GO:0009987;protein-containing complex organization#GO:0043933 zinc finger transcription factor#PC00244 CIOIN|Ensembl=ENSCING00000006684.3|UniProtKB=F7BAF2 F7BAF2 LOC445732 PTHR11814:SF272 SULFATE TRANSPORTER SOLUTE CARRIER FAMILY 26 MEMBER 10P-RELATED inorganic molecular entity transmembrane transporter activity#GO:0015318;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;organic acid transmembrane transporter activity#GO:0005342;chloride transmembrane transporter activity#GO:0015108;monoatomic anion transmembrane transporter activity#GO:0008509;organic anion transmembrane transporter activity#GO:0008514;inorganic anion transmembrane transporter activity#GO:0015103;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 transporter#PC00227 CIOIN|Ensembl=ENSCING00000003892.3|UniProtKB=L7N0R8 L7N0R8 PTHR48041:SF116 ABC TRANSPORTER G FAMILY MEMBER 28 PROTEIN BROWN transmembrane transporter activity#GO:0022857;primary active transmembrane transporter activity#GO:0015399;ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 localization#GO:0051179;cellular process#GO:0009987;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 ATP-binding cassette (ABC) transporter#PC00003;transporter#PC00227 CIOIN|Ensembl=ENSCING00000004739.3|UniProtKB=F6RJ12 F6RJ12 PTHR12400:SF26 INOSITOL POLYPHOSPHATE KINASE KINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;phosphotransferase activity, phosphate group as acceptor#GO:0016776 organic hydroxy compound metabolic process#GO:1901615;lipid metabolic process#GO:0006629;phospholipid biosynthetic process#GO:0008654;organophosphate biosynthetic process#GO:0090407;phosphatidylinositol biosynthetic process#GO:0006661;glycerolipid biosynthetic process#GO:0045017;alcohol biosynthetic process#GO:0046165;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic hydroxy compound biosynthetic process#GO:1901617;phosphatidylinositol metabolic process#GO:0046488;glycerophospholipid metabolic process#GO:0006650;alcohol metabolic process#GO:0006066;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;phosphatidylinositol phosphate biosynthetic process#GO:0046854;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;glycerophospholipid biosynthetic process#GO:0046474;organophosphate metabolic process#GO:0019637;small molecule biosynthetic process#GO:0044283;cellular lipid metabolic process#GO:0044255;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 kinase#PC00137 CIOIN|Ensembl=ENSCING00000006388.3|UniProtKB=F6RK00 F6RK00 LOC100180174 PTHR45754:SF3 METHYLENETETRAHYDROFOLATE REDUCTASE METHYLENETETRAHYDROFOLATE REDUCTASE (NADPH) nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;flavin adenine dinucleotide binding#GO:0050660;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167;oxidoreductase activity#GO:0016491 cellular aromatic compound metabolic process#GO:0006725;sulfur compound metabolic process#GO:0006790;proteinogenic amino acid biosynthetic process#GO:0170038;folic acid-containing compound metabolic process#GO:0006760;biosynthetic process#GO:0009058;carboxylic acid biosynthetic process#GO:0046394;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular modified amino acid metabolic process#GO:0006575;amino acid biosynthetic process#GO:0008652;alpha-amino acid metabolic process#GO:1901605;L-amino acid metabolic process#GO:0170033;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;proteinogenic amino acid metabolic process#GO:0170039;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;aspartate family amino acid biosynthetic process#GO:0009067;alpha-amino acid biosynthetic process#GO:1901607;aspartate family amino acid metabolic process#GO:0009066;L-amino acid biosynthetic process#GO:0170034;small molecule biosynthetic process#GO:0044283;carboxylic acid metabolic process#GO:0019752;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 reductase#PC00198;oxidoreductase#PC00176 CIOIN|Gene=APTX|UniProtKB=P61802 P61802 APTX PTHR12486:SF4 APRATAXIN-RELATED APRATAXIN hydrolase activity, acting on ester bonds#GO:0016788;nucleic acid binding#GO:0003676;DNA exonuclease activity, producing 5'-phosphomonoesters#GO:0016895;nuclease activity#GO:0004518;DNA exonuclease activity#GO:0004529;5'-3' exonuclease activity#GO:0008409;binding#GO:0005488;catalytic activity#GO:0003824;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters#GO:0016796;single-stranded DNA binding#GO:0003697;damaged DNA binding#GO:0003684;catalytic activity, acting on a nucleic acid#GO:0140640;double-stranded DNA binding#GO:0003690;exonuclease activity#GO:0004527;RNA binding#GO:0003723;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;hydrolase activity#GO:0016787;DNA nuclease activity#GO:0004536;catalytic activity, acting on DNA#GO:0140097;double-stranded RNA binding#GO:0003725 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;DNA damage response#GO:0006974;response to stress#GO:0006950;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular response to stress#GO:0033554;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 damaged DNA-binding protein#PC00086;DNA metabolism protein#PC00009 CIOIN|Ensembl=ENSCING00000023844.1|UniProtKB=H2XUP2 H2XUP2 PTHR45701:SF13 SYNAPTOBREVIN FAMILY MEMBER V-SNARE COILED-COIL HOMOLOGY DOMAIN-CONTAINING PROTEIN syntaxin binding#GO:0019905;molecular adaptor activity#GO:0060090;protein binding#GO:0005515;SNAP receptor activity#GO:0005484;binding#GO:0005488;SNARE binding#GO:0000149;protein-macromolecule adaptor activity#GO:0030674 vesicle fusion#GO:0006906;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;transport#GO:0006810;protein-containing complex assembly#GO:0065003;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;membrane fusion#GO:0061025;establishment of localization#GO:0051234;protein-containing complex organization#GO:0043933;organelle organization#GO:0006996;vesicle organization#GO:0016050;organelle fusion#GO:0048284 cytoplasm#GO:0005737;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;SNARE complex#GO:0031201;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150 CIOIN|Ensembl=ENSCING00000009109.3|UniProtKB=F6Q929 F6Q929 LOC100181888 PTHR43675:SF8 ARSENITE METHYLTRANSFERASE ARSENITE METHYLTRANSFERASE methyltransferase activity#GO:0008168;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824 methyltransferase#PC00155;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000005242.3|UniProtKB=F6YH17 F6YH17 PTHR13935:SF153 ACHAETE-SCUTE TRANSCRIPTION FACTOR-RELATED ACHAETE-SCUTE FAMILY BHLH TRANSCRIPTION FACTOR 1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of nitrogen compound metabolic process#GO:0051173;neurogenesis#GO:0022008;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nitrogen compound metabolic process#GO:0051171;animal organ development#GO:0048513;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;regulation of cell differentiation#GO:0045595;regulation of multicellular organismal development#GO:2000026;nervous system development#GO:0007399;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;neuron differentiation#GO:0030182;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;cellular developmental process#GO:0048869;regulation of multicellular organismal process#GO:0051239;regulation of cell development#GO:0060284;regulation of DNA-templated transcription#GO:0006355;multicellular organism development#GO:0007275;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of neurogenesis#GO:0050767;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;positive regulation of RNA metabolic process#GO:0051254;generation of neurons#GO:0048699;sensory organ development#GO:0007423;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;basic helix-loop-helix transcription factor#PC00055 CIOIN|Ensembl=ENSCING00000007860.3|UniProtKB=F6VJH0 F6VJH0 PTHR22762:SF133 ALPHA-GLUCOSIDASE P-TYPE DOMAIN-CONTAINING PROTEIN hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 glucosidase#PC00108;metabolite interconversion enzyme#PC00262;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000008926.3|UniProtKB=F6QAA1 F6QAA1 LOC100178755 PTHR48177:SF1 TRANSMEMBRANE PROTEIN 189 PLASMANYLETHANOLAMINE DESATURASE 1 oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 CIOIN|Ensembl=ENSCING00000005557.3|UniProtKB=F6VGH4 F6VGH4 LOC100175572 PTHR10454:SF31 CASPASE CASPASE-7 cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197;hydrolase activity#GO:0016787;cysteine-type endopeptidase activity involved in apoptotic process#GO:0097153;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 regulation of biological process#GO:0050789;positive regulation of apoptotic process#GO:0043065;positive regulation of programmed cell death#GO:0043068;regulation of apoptotic process#GO:0042981;regulation of cellular process#GO:0050794;apoptotic process#GO:0006915;biological regulation#GO:0065007;cell death#GO:0008219;programmed cell death#GO:0012501;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;regulation of programmed cell death#GO:0043067;positive regulation of cellular process#GO:0048522 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 protease#PC00190;protein modifying enzyme#PC00260 FAS signaling pathway#P00020>Caspase7#P00595;Apoptosis signaling pathway#P00006>Caspase 7#P00300;FAS signaling pathway#P00020>Pro-Caspase7#P00605 CIOIN|Ensembl=ENSCING00000008878.3|UniProtKB=F6QXK6 F6QXK6 LOC100184954 PTHR24098:SF0 OUTER SEGMENT 5 OUTER SEGMENT 5 organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cell projection organization#GO:0030030;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031 protein-containing complex#GO:0032991;intraciliary transport particle B#GO:0030992;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;cilium#GO:0005929;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intraciliary transport particle#GO:0030990 CIOIN|Ensembl=ENSCING00000009824.3|UniProtKB=F6Y4Z5 F6Y4Z5 LOC100181673 PTHR21397:SF4 CHROMATIN COMPLEXES SUBUNIT BAP18-RELATED ER MEMBRANE PROTEIN COMPLEX SUBUNIT 10 chromatin/chromatin-binding, or -regulatory protein#PC00077 CIOIN|Ensembl=ENSCING00000010411.3|UniProtKB=F7B2Q1 F7B2Q1 LOC100181871 PTHR19957:SF3 SYNTAXIN SYNTAXIN-5 molecular adaptor activity#GO:0060090;protein binding#GO:0005515;SNAP receptor activity#GO:0005484;binding#GO:0005488;SNARE binding#GO:0000149;protein-macromolecule adaptor activity#GO:0030674 endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;vesicle fusion#GO:0006906;cellular localization#GO:0051641;organelle localization#GO:0051640;macromolecule localization#GO:0033036;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;membrane fusion#GO:0061025;establishment of localization#GO:0051234;organelle organization#GO:0006996;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;vesicle organization#GO:0016050;intracellular transport#GO:0046907;organelle fusion#GO:0048284 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;SNARE complex#GO:0031201;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;Golgi membrane#GO:0000139 SNARE protein#PC00034;membrane traffic protein#PC00150 Nicotinic acetylcholine receptor signaling pathway#P00044>SNARE Complex#P01091;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>SNARE Complex#P01079 CIOIN|Ensembl=ENSCING00000007768.3|UniProtKB=F6XTL0 F6XTL0 PTHR19300:SF61 BETA-1,4-GALACTOSYLTRANSFERASE BETA-1,4-N-ACETYLGALACTOSAMINYLTRANSFERASE galactosyltransferase activity#GO:0008378;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 glycosylation#GO:0070085;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000020722.1|UniProtKB=H2XRA3 H2XRA3 PTHR21162:SF0 P53 AND DNA DAMAGE-REGULATED PROTEIN P53 AND DNA DAMAGE-REGULATED PROTEIN 1 CIOIN|Ensembl=ENSCING00000004647.2|UniProtKB=F6RNA2 F6RNA2 LOC100176602 PTHR43591:SF101 METHYLTRANSFERASE METHYLTRANSFERASE-LIKE PROTEIN 27 methyltransferase#PC00155;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000018213.1|UniProtKB=H2Y0I2 H2Y0I2 PTHR13628:SF1 TRANSMEMBRANE PROTEIN 267 TRANSMEMBRANE PROTEIN 267 CIOIN|Ensembl=ENSCING00000016699.2|UniProtKB=F6RTY1 F6RTY1 LOC100186946 PTHR12940:SF0 ES-2 PROTEIN - RELATED SPLICING FACTOR ESS-2 HOMOLOG ribonucleoprotein complex#GO:1990904;catalytic step 2 spliceosome#GO:0071013;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000000734.3|UniProtKB=F6Q2Q3 F6Q2Q3 PTHR15859:SF1 SETA BINDING PROTEIN 1 BTB DOMAIN-CONTAINING PROTEIN scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000014892.2|UniProtKB=F6YRR0 F6YRR0 LOC101243418 PTHR11545:SF3 RIBOSOMAL PROTEIN L13 LARGE RIBOSOMAL SUBUNIT PROTEIN UL13 structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;structural molecule activity#GO:0005198;binding#GO:0005488;organic cyclic compound binding#GO:0097159 negative regulation of gene expression#GO:0010629;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;negative regulation of biosynthetic process#GO:0009890;regulation of amide metabolic process#GO:0034248;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of translation#GO:0017148;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;post-transcriptional regulation of gene expression#GO:0010608;biological regulation#GO:0065007;regulation of translation#GO:0006417;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic large ribosomal subunit#GO:0022625;large ribosomal subunit#GO:0015934;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000014224.2|UniProtKB=F6Y0T9 F6Y0T9 PTHR11373:SF4 DEOXYNUCLEOSIDE TRIPHOSPHATE TRIPHOSPHOHYDROLASE DEOXYNUCLEOSIDE TRIPHOSPHATE TRIPHOSPHOHYDROLASE SAMHD1 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 cellular aromatic compound metabolic process#GO:0006725;nucleoside triphosphate metabolic process#GO:0009141;carbohydrate derivative metabolic process#GO:1901135;heterocycle catabolic process#GO:0046700;organonitrogen compound catabolic process#GO:1901565;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;purine-containing compound catabolic process#GO:0072523;phosphate-containing compound metabolic process#GO:0006796;cellular nitrogen compound catabolic process#GO:0044270;organic cyclic compound metabolic process#GO:1901360;purine nucleotide catabolic process#GO:0006195;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;purine nucleotide metabolic process#GO:0006163;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;nucleoside phosphate catabolic process#GO:1901292;carbohydrate derivative catabolic process#GO:1901136;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;nucleotide catabolic process#GO:0009166;nucleoside triphosphate catabolic process#GO:0009143;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organophosphate catabolic process#GO:0046434;primary metabolic process#GO:0044238;aromatic compound catabolic process#GO:0019439;organic cyclic compound catabolic process#GO:1901361;organophosphate metabolic process#GO:0019637;purine nucleoside triphosphate metabolic process#GO:0009144;nucleobase-containing compound catabolic process#GO:0034655;nucleotide metabolic process#GO:0009117;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000000662.3|UniProtKB=F6QWY8 F6QWY8 PTHR24056:SF400 CELL DIVISION PROTEIN KINASE KINASE, PUTATIVE-RELATED transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;phosphorylation#GO:0016310;protein phosphorylation#GO:0006468;cellular process#GO:0009987;protein metabolic process#GO:0019538;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 CIOIN|Ensembl=ENSCING00000002291.3|UniProtKB=F6VF67 F6VF67 PTHR31322:SF2 E3 UBIQUITIN-PROTEIN LIGASE TM129 E3 UBIQUITIN-PROTEIN LIGASE TM129 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000002555.3|UniProtKB=F6X2D7 F6X2D7 LOC100184571 PTHR15462:SF8 SERINE PROTEASE SERINE PROTEASE serine protease#PC00203 CIOIN|Ensembl=ENSCING00000004863.3|UniProtKB=Q1RPZ1 Q1RPZ1 Ci-ZF(C2H2)-93 PTHR24409:SF417 ZINC FINGER PROTEIN 142 SERENDIPITY LOCUS PROTEIN BETA-RELATED sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 CIOIN|Ensembl=ENSCING00000004464.3|UniProtKB=F6US70 F6US70 LOC100181706 PTHR10334:SF590 CYSTEINE-RICH SECRETORY PROTEIN-RELATED SCP DOMAIN-CONTAINING PROTEIN extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 defense/immunity protein#PC00090 CIOIN|Ensembl=ENSCING00000006430.3|UniProtKB=F6QQZ3 F6QQZ3 PTHR10681:SF171 THIOREDOXIN PEROXIDASE PEROXIREDOXIN 4 oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;antioxidant activity#GO:0016209;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;response to stress#GO:0006950;catabolic process#GO:0009056;cellular metabolic process#GO:0044237;homeostatic process#GO:0042592;response to oxidative stress#GO:0006979;cellular process#GO:0009987;cellular response to stress#GO:0033554;cellular homeostasis#GO:0019725;cellular catabolic process#GO:0044248;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 peroxidase#PC00180;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000009658.3|UniProtKB=Q9NL46 Q9NL46 CiDsh PTHR10878:SF25 SEGMENT POLARITY PROTEIN DISHEVELLED SEGMENT POLARITY PROTEIN DISHEVELLED regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;cell-cell signaling by wnt#GO:0198738;canonical Wnt signaling pathway#GO:0060070;cell-cell signaling#GO:0007267;signaling#GO:0023052;Wnt signaling pathway#GO:0016055 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 Angiogenesis#P00005>Dsh#P00200;Wnt signaling pathway#P00057>Dishevelled#P01447 CIOIN|Ensembl=ENSCING00000006386.3|UniProtKB=F6QR00 F6QR00 PTHR20856:SF7 DNA-DIRECTED RNA POLYMERASE I SUBUNIT 2 DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB2 catalytic activity, acting on RNA#GO:0140098;5'-3' RNA polymerase activity#GO:0034062;transferase activity#GO:0016740;DNA-directed 5'-3' RNA polymerase activity#GO:0003899;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;RNA polymerase activity#GO:0097747;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring phosphorus-containing groups#GO:0016772 RNA metabolism protein#PC00031;DNA-directed RNA polymerase#PC00019 CIOIN|Ensembl=ENSCING00000006043.3|UniProtKB=F7BLJ0 F7BLJ0 PTHR11654:SF509 OLIGOPEPTIDE TRANSPORTER-RELATED SOLUTE CARRIER FAMILY 15 MEMBER 4 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 localization#GO:0051179;establishment of localization#GO:0051234;cellular process#GO:0009987;transmembrane transport#GO:0055085;transport#GO:0006810 cellular anatomical entity#GO:0110165;membrane#GO:0016020 transporter#PC00227 CIOIN|Ensembl=ENSCING00000011599.2|UniProtKB=F6S1A9 F6S1A9 PTHR45808:SF2 RHO GTPASE-ACTIVATING PROTEIN 68F RHO GTPASE-ACTIVATING PROTEIN 68F nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;small GTPase-mediated signal transduction#GO:0007264;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;cellular process#GO:0009987;signaling#GO:0023052 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 GTPase-activating protein#PC00257 VEGF signaling pathway#P00056>Rac#P01421;Angiogenesis#P00005>Rac#P00245;Cytoskeletal regulation by Rho GTPase#P00016>Rho GAPs#P00520;PDGF signaling pathway#P00047>Rho#P01174 CIOIN|Ensembl=ENSCING00000009826.3|UniProtKB=F6UE78 F6UE78 PTHR12196:SF2 DOMAIN OF UNKNOWN FUNCTION 71 DUF71 -CONTAINING PROTEIN DIPHTHINE--AMMONIA LIGASE ligase activity#GO:0016874;catalytic activity#GO:0003824 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;primary metabolic process#GO:0044238 CIOIN|Ensembl=ENSCING00000021526.1|UniProtKB=H2Y0Q1 H2Y0Q1 PTHR43651:SF3 1,4-ALPHA-GLUCAN-BRANCHING ENZYME 1,4-ALPHA-GLUCAN-BRANCHING ENZYME transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 carbohydrate metabolic process#GO:0005975;organic substance metabolic process#GO:0071704;primary metabolic process#GO:0044238;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 amylase#PC00048;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000006856.3|UniProtKB=Q4H389 Q4H389 Ci-Lmx PTHR24208:SF166 LIM/HOMEOBOX PROTEIN LHX LIM HOMEOBOX TRANSCRIPTION FACTOR 1 ALPHA, ISOFORM B sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 homeodomain transcription factor#PC00119 CIOIN|Ensembl=ENSCING00000010116.3|UniProtKB=F6PIG9 F6PIG9 LOC100182534 PTHR12937:SF0 VACUOLAR PROTEIN SORTING 28, ISOFORM 2 VPS28 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 28 HOMOLOG protein-containing complex binding#GO:0044877;binding#GO:0005488 endosomal transport#GO:0016197;cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;protein catabolic process#GO:0030163;late endosome to vacuole transport via multivesicular body sorting pathway#GO:0032511;nitrogen compound transport#GO:0071705;organonitrogen compound catabolic process#GO:1901565;late endosome to vacuole transport#GO:0045324;protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043328;establishment of protein localization#GO:0045184;ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043162;modification-dependent macromolecule catabolic process#GO:0043632;organic substance transport#GO:0071702;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;protein localization to organelle#GO:0033365;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;establishment of protein localization to vacuole#GO:0072666;modification-dependent protein catabolic process#GO:0019941;vacuolar transport#GO:0007034;macromolecule metabolic process#GO:0043170;protein localization to vacuole#GO:0072665;organonitrogen compound metabolic process#GO:1901564;establishment of protein localization to organelle#GO:0072594;vesicle-mediated transport#GO:0016192;multivesicular body sorting pathway#GO:0071985;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein localization#GO:0008104;ubiquitin-dependent protein catabolic process#GO:0006511;localization#GO:0051179;cellular macromolecule localization#GO:0070727;protein transport#GO:0015031;endosome transport via multivesicular body sorting pathway#GO:0032509;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;endosome#GO:0005768;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endosome membrane#GO:0010008;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;ESCRT I complex#GO:0000813;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cytoplasmic vesicle membrane#GO:0030659 membrane traffic protein#PC00150 CIOIN|Ensembl=ENSCING00000001883.1|UniProtKB=F6SJ02 F6SJ02 LOC100179863 PTHR24253:SF55 TRANSMEMBRANE PROTEASE SERINE TRANSMEMBRANE PROTEASE SERINE 13 serine protease#PC00203;protease#PC00190 CIOIN|Ensembl=ENSCING00000001341.3|UniProtKB=F6VMU0 F6VMU0 LOC100181328 PTHR11786:SF0 N-HYDROXYARYLAMINE O-ACETYLTRANSFERASE ARYLAMINE N-ACETYLTRANSFERASE 4-RELATED acetyltransferase#PC00038 CIOIN|Ensembl=ENSCING00000001381.3|UniProtKB=Q4H3Q3 Q4H3Q3 Ci-dickkopf PTHR12113:SF6 DICKKOPF3-LIKE 3 DICKKOPF N-TERMINAL CYSTEINE-RICH DOMAIN-CONTAINING PROTEIN signaling receptor regulator activity#GO:0030545;protein binding#GO:0005515;molecular function inhibitor activity#GO:0140678;binding#GO:0005488;molecular function regulator activity#GO:0098772;signaling receptor binding#GO:0005102 regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;negative regulation of response to stimulus#GO:0048585;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;regulation of canonical Wnt signaling pathway#GO:0060828;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;regulation of Wnt signaling pathway#GO:0030111;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of canonical Wnt signaling pathway#GO:0090090;negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 membrane trafficking regulatory protein#PC00151 CIOIN|Ensembl=ENSCING00000011719.2|UniProtKB=F6W097 F6W097 PTHR43184:SF12 MAJOR FACILITATOR SUPERFAMILY TRANSPORTER 16, ISOFORM B SUGAR PHOSPHATE EXCHANGER 3 transporter#PC00227 CIOIN|Ensembl=ENSCING00000008991.3|UniProtKB=F6PHB9 F6PHB9 PTHR10676:SF361 DYNEIN HEAVY CHAIN FAMILY PROTEIN DYNEIN AXONEMAL HEAVY CHAIN 8 cytoskeletal motor activity#GO:0003774;microtubule motor activity#GO:0003777;protein binding#GO:0005515;ATP-dependent activity#GO:0140657;binding#GO:0005488 cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;outer dynein arm assembly#GO:0036158;cell projection organization#GO:0030030;microtubule-based movement#GO:0007018;microtubule cytoskeleton organization#GO:0000226;cilium or flagellum-dependent cell motility#GO:0001539;protein-containing complex assembly#GO:0065003;cell motility#GO:0048870;cellular component organization#GO:0016043;axoneme assembly#GO:0035082;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031;cilium movement involved in cell motility#GO:0060294;cilium movement#GO:0003341;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cilium-dependent cell motility#GO:0060285;microtubule-based process#GO:0007017;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;microtubule bundle formation#GO:0001578;axonemal dynein complex assembly#GO:0070286;cytoskeleton organization#GO:0007010;plasma membrane bounded cell projection assembly#GO:0120031 axoneme#GO:0005930;outer dynein arm#GO:0036157;catalytic complex#GO:1902494;cytoplasmic region#GO:0099568;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;sperm flagellum#GO:0036126;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;microtubule associated complex#GO:0005875;axonemal dynein complex#GO:0005858;non-membrane-bounded organelle#GO:0043228;motile cilium#GO:0031514;protein-containing complex#GO:0032991;9+2 motile cilium#GO:0097729;microtubule cytoskeleton#GO:0015630;ciliary plasm#GO:0097014;plasma membrane bounded cell projection cytoplasm#GO:0032838;membrane-bounded organelle#GO:0043227;dynein complex#GO:0030286;cell projection#GO:0042995;cytoskeleton#GO:0005856;cilium#GO:0005929 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 Huntington disease#P00029>Dynein complex#P00774 CIOIN|Ensembl=ENSCING00000005418.3|UniProtKB=F6Z987 F6Z987 PTHR24115:SF194 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF6 pyrophosphatase activity#GO:0016462;cytoskeletal protein binding#GO:0008092;microtubule motor activity#GO:0003777;tubulin binding#GO:0015631;ATP-dependent activity#GO:0140657;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;cytoskeletal motor activity#GO:0003774;microtubule binding#GO:0008017;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;ribonucleoside triphosphate phosphatase activity#GO:0017111;ATP hydrolysis activity#GO:0016887 microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;microtubule associated complex#GO:0005875;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 CIOIN|Ensembl=ENSCING00000008010.3|UniProtKB=F6ZFS8 F6ZFS8 PTHR11101:SF80 PHOSPHATE TRANSPORTER PHOSPHATE TRANSPORTER inorganic molecular entity transmembrane transporter activity#GO:0015318;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 localization#GO:0051179;inorganic anion transmembrane transport#GO:0098661;phosphate ion transport#GO:0006817;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;transport#GO:0006810;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;inorganic anion transport#GO:0015698 transporter#PC00227 CIOIN|Ensembl=ENSCING00000006695.3|UniProtKB=F6Y6F6 F6Y6F6 PTHR43539:SF23 FLAVIN-BINDING MONOOXYGENASE-LIKE PROTEIN (AFU_ORTHOLOGUE AFUA_4G09220) FAD-DEPENDENT OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN 2 nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;flavin adenine dinucleotide binding#GO:0050660;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;anion binding#GO:0043168;oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497 response to organic substance#GO:0010033;macromolecule catabolic process#GO:0009057;cellular response to stimulus#GO:0051716;response to endoplasmic reticulum stress#GO:0034976;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;response to organonitrogen compound#GO:0010243;ERAD pathway#GO:0036503;cellular process#GO:0009987;primary metabolic process#GO:0044238;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;cellular response to stress#GO:0033554;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;endoplasmic reticulum lumen#GO:0005788;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 oxygenase#PC00177;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000005453.3|UniProtKB=F6UTT2 F6UTT2 PTHR12670:SF1 CERAMIDASE NEUTRAL CERAMIDASE hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;alcohol biosynthetic process#GO:0046165;organonitrogen compound catabolic process#GO:1901565;organic hydroxy compound biosynthetic process#GO:1901617;lipid catabolic process#GO:0016042;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;sphingolipid metabolic process#GO:0006665;carboxylic acid biosynthetic process#GO:0046394;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;sphingolipid catabolic process#GO:0030149;cellular lipid catabolic process#GO:0044242;amide metabolic process#GO:0043603;sphingolipid biosynthetic process#GO:0030148;fatty acid biosynthetic process#GO:0006633;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;long-chain fatty acid metabolic process#GO:0001676;organic hydroxy compound metabolic process#GO:1901615;organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;monocarboxylic acid biosynthetic process#GO:0072330;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;alcohol metabolic process#GO:0006066;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;membrane lipid biosynthetic process#GO:0046467;monocarboxylic acid metabolic process#GO:0032787;ceramide metabolic process#GO:0006672;primary metabolic process#GO:0044238;fatty acid metabolic process#GO:0006631;membrane lipid metabolic process#GO:0006643;small molecule biosynthetic process#GO:0044283;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281 cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 CIOIN|Ensembl=ENSCING00000023982.1|UniProtKB=F6RXE4 F6RXE4 PTHR22298:SF29 ENDO-1,4-BETA-GLUCANASE ENDOGLUCANASE CIOIN|Ensembl=ENSCING00000020287.1|UniProtKB=H2XQR3 H2XQR3 PTHR13809:SF27 GUANINE NUCLEOTIDE-BINDING PROTEIN GAMMA SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN SUBUNIT GAMMA protein binding#GO:0005515;binding#GO:0005488 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;plasma membrane protein complex#GO:0098797;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;cytoplasmic side of plasma membrane#GO:0009898;extrinsic component of membrane#GO:0019898;plasma membrane#GO:0005886 heterotrimeric G-protein#PC00117;G-protein#PC00020 Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>G-Protein#P01085;5HT2 type receptor mediated signaling pathway#P04374>G-protein#P04416;Cortocotropin releasing factor receptor signaling pathway#P04380>G-Protein#P04458;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>G-Protein#P01073;Metabotropic glutamate receptor group II pathway#P00040>G-protein#P01047 CIOIN|Ensembl=ENSCING00000006379.3|UniProtKB=F6RL73 F6RL73 LOC100179098 PTHR44027:SF7 DNAJ HOMOLOG SUBFAMILY C MEMBER 5 HOMOLOG DNAJ HOMOLOG SUBFAMILY C MEMBER 5 HOMOLOG chaperone#PC00072 CIOIN|Ensembl=ENSCING00000005592.3|UniProtKB=F7BBT3 F7BBT3 PTHR23115:SF188 TRANSLATION FACTOR HBS1-LIKE PROTEIN GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;translation#GO:0006412;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 translation factor#PC00223;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000012237.2|UniProtKB=F7B5T8 F7B5T8 PTHR14002:SF20 ENDOGLIN/TGF-BETA RECEPTOR TYPE III ZONA PELLUCIDA-LIKE DOMAIN-CONTAINING PROTEIN 1 transmembrane signal receptor#PC00197 CIOIN|Ensembl=ENSCING00000009127.4|UniProtKB=Q1RL41 Q1RL41 Ci-ZF(DHHC)-8 PTHR12246:SF13 PALMITOYLTRANSFERASE ZDHHC16 PALMITOYLTRANSFERASE ZDHHC16 protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000004737.3|UniProtKB=F6PWJ2 F6PWJ2 PTHR33504:SF1 NADH DEHYDROGENASE (UBIQUINONE) 1 BETA SUBCOMPLEX, 4 FAMILY WITH SEQUENCE SIMILARITY 90, MEMBER A1B dehydrogenase#PC00092;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000002557.3|UniProtKB=F6X2C4 F6X2C4 LOC100182407 PTHR11024:SF2 NUCLEAR PORE COMPLEX PROTEIN SEC13 / SEH1 FAMILY MEMBER PROTEIN SEC13 HOMOLOG endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;macromolecule localization#GO:0033036;membrane organization#GO:0061024;transport#GO:0006810;protein localization to nucleus#GO:0034504;nitrogen compound transport#GO:0071705;establishment of protein localization#GO:0045184;organic substance transport#GO:0071702;protein import into nucleus#GO:0006606;establishment of localization#GO:0051234;vesicle organization#GO:0016050;protein localization to organelle#GO:0033365;nuclear transport#GO:0051169;establishment of protein localization to organelle#GO:0072594;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;vesicle budding from membrane#GO:0006900;nucleocytoplasmic transport#GO:0006913;organelle organization#GO:0006996;protein transport#GO:0015031;COPII-coated vesicle budding#GO:0090114;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;import into nucleus#GO:0051170 bounding membrane of organelle#GO:0098588;COPII-coated ER to Golgi transport vesicle#GO:0030134;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;transport vesicle membrane#GO:0030658;membrane coat#GO:0030117;coated membrane#GO:0048475;cytoplasmic vesicle membrane#GO:0030659;envelope#GO:0031975;nuclear pore#GO:0005643;membrane protein complex#GO:0098796;ER to Golgi transport vesicle membrane#GO:0012507;nucleus#GO:0005634;intracellular vesicle#GO:0097708;membrane#GO:0016020;coated vesicle#GO:0030135;vesicle coat#GO:0030120;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;coated vesicle membrane#GO:0030662;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;transport vesicle#GO:0030133;nuclear protein-containing complex#GO:0140513 transporter#PC00227 CIOIN|Ensembl=ENSCING00000017995.1|UniProtKB=F6YNZ8 F6YNZ8 LOC100175559 PTHR10671:SF108 EPITHELIAL MEMBRANE PROTEIN-RELATED CLAUDIN FAMILY PROTEIN-RELATED cytoskeletal protein#PC00085 CIOIN|Ensembl=ENSCING00000009648.3|UniProtKB=F6XH93 F6XH93 LOC100186863 PTHR12259:SF1 RGS-GAIP INTERACTING PROTEIN GIPC GH21964P scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000000306.3|UniProtKB=F6ZGB0 F6ZGB0 LOC100180412 PTHR44086:SF10 THIOSULFATE SULFURTRANSFERASE RDL2, MITOCHONDRIAL-RELATED THIOSULFATE SULFURTRANSFERASE_RHODANESE-LIKE DOMAIN-CONTAINING PROTEIN 3 thiosulfate sulfurtransferase activity#GO:0004792;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824;sulfurtransferase activity#GO:0016783 transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000013735.2|UniProtKB=F6PM15 F6PM15 PTHR12700:SF12 ATP SYNTHASE SUBUNIT D, MITOCHONDRIAL ATP SYNTHASE SUBUNIT D, MITOCHONDRIAL monoatomic cation channel activity#GO:0005261;ligase activity#GO:0016874;inorganic molecular entity transmembrane transporter activity#GO:0015318;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;catalytic activity#GO:0003824;proton transmembrane transporter activity#GO:0015078;proton channel activity#GO:0015252;proton-transporting ATP synthase activity, rotational mechanism#GO:0046933;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;inorganic cation transmembrane transporter activity#GO:0022890;channel activity#GO:0015267;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 cellular aromatic compound metabolic process#GO:0006725;ribonucleoside triphosphate metabolic process#GO:0009199;nucleoside triphosphate metabolic process#GO:0009141;carbohydrate derivative metabolic process#GO:1901135;ATP biosynthetic process#GO:0006754;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ATP metabolic process#GO:0046034;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;purine nucleoside triphosphate biosynthetic process#GO:0009145;heterocycle metabolic process#GO:0046483;purine ribonucleoside triphosphate metabolic process#GO:0009205;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;ribonucleoside triphosphate biosynthetic process#GO:0009201;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;proton motive force-driven ATP synthesis#GO:0015986;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;nucleoside triphosphate biosynthetic process#GO:0009142;organophosphate metabolic process#GO:0019637;purine nucleoside triphosphate metabolic process#GO:0009144;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;proton-transporting two-sector ATPase complex, proton-transporting domain#GO:0033177;ATPase complex#GO:1904949;organelle inner membrane#GO:0019866;mitochondrial proton-transporting ATP synthase complex#GO:0005753;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;proton-transporting two-sector ATPase complex#GO:0016469;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)#GO:0000276;mitochondrial envelope#GO:0005740;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227;proton-transporting ATP synthase complex, coupling factor F(o)#GO:0045263;proton-transporting ATP synthase complex#GO:0045259;mitochondrial protein-containing complex#GO:0098798 ATP synthase#PC00002;primary active transporter#PC00068;transporter#PC00227 CIOIN|Ensembl=ENSCING00000009631.3|UniProtKB=F6ZUA8 F6ZUA8 PTHR23301:SF0 CHITIN BINDING PERITROPHIN-A CHITIN-BINDING TYPE-2 DOMAIN-CONTAINING PROTEIN-RELATED CIOIN|Ensembl=ENSCING00000006168.3|UniProtKB=F7BL69 F7BL69 PTHR22874:SF1 ACTIVATING MOLECULE IN BECN1-REGULATED AUTOPHAGY PROTEIN 1 ACTIVATING MOLECULE IN BECN1-REGULATED AUTOPHAGY PROTEIN 1 ubiquitin ligase-substrate adaptor activity#GO:1990756;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;macroautophagy#GO:0016236;mitophagy#GO:0000423;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;autophagy of mitochondrion#GO:0000422;cellular process#GO:0009987;organelle disassembly#GO:1903008;organelle assembly#GO:0070925;process utilizing autophagic mechanism#GO:0061919;cellular component organization or biogenesis#GO:0071840;vacuole organization#GO:0007033;cellular component disassembly#GO:0022411;organelle organization#GO:0006996;autophagosome assembly#GO:0000045;catabolic process#GO:0009056;mitochondrion organization#GO:0007005;autophagy#GO:0006914;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;intracellular membrane-bounded organelle#GO:0043231;cullin-RING ubiquitin ligase complex#GO:0031461;catalytic complex#GO:1902494;transferase complex#GO:1990234;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;Cul4-RING E3 ubiquitin ligase complex#GO:0080008;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000024525.1|UniProtKB=H2Y072 H2Y072 PTHR32178:SF6 FAM187 IG-LIKE DOMAIN-CONTAINING PROTEIN immunoglobulin superfamily cell adhesion molecule#PC00125 CIOIN|Ensembl=ENSCING00000020170.1|UniProtKB=H2XMW2 H2XMW2 PTHR46550:SF1 F-BOX ONLY PROTEIN 3 F-BOX PROTEIN 3 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000002967.3|UniProtKB=F6R3R2 F6R3R2 LOC494397 PTHR14002:SF54 ENDOGLIN/TGF-BETA RECEPTOR TYPE III ZONA PELLUCIDA SPERM-BINDING PROTEIN 2 transmembrane signal receptor#PC00197 CIOIN|Ensembl=ENSCING00000024234.1|UniProtKB=H2XWH6 H2XWH6 LOC100181076 PTHR31462:SF5 ENDOSOMAL/LYSOSOMAL POTASSIUM CHANNEL TMEM175 ENDOSOMAL_LYSOSOMAL PROTON CHANNEL TMEM175 ion channel#PC00133;transporter#PC00227 CIOIN|Ensembl=ENSCING00000022727.1|UniProtKB=H2XM97 H2XM97 LOC100177768 PTHR31921:SF1 PROTEIN DPCD PROTEIN DPCD CIOIN|Ensembl=ENSCING00000008044.3|UniProtKB=F6S5A6 F6S5A6 PTHR11963:SF48 LEUCINE AMINOPEPTIDASE-RELATED DIPEPTIDASE B, ISOFORM A hydrolase activity#GO:0016787;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 metalloprotease#PC00153;protease#PC00190 CIOIN|Ensembl=ENSCING00000008924.3|UniProtKB=F6QAK1 F6QAK1 LOC100185844 PTHR10794:SF45 ABHYDROLASE DOMAIN-CONTAINING PROTEIN MONOACYLGLYCEROL LIPASE ABHD2 hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;catalytic activity#GO:0003824 male gamete generation#GO:0048232;neutral lipid catabolic process#GO:0046461;lipid catabolic process#GO:0016042;acylglycerol metabolic process#GO:0006639;lipid biosynthetic process#GO:0008610;hormone-mediated signaling pathway#GO:0009755;carboxylic acid biosynthetic process#GO:0046394;neutral lipid metabolic process#GO:0006638;regulation of biological process#GO:0050789;cellular response to hormone stimulus#GO:0032870;spermatogenesis#GO:0007283;reproductive process#GO:0022414;carboxylic acid catabolic process#GO:0046395;cellular lipid catabolic process#GO:0044242;multicellular organismal reproductive process#GO:0048609;organic substance metabolic process#GO:0071704;germ cell development#GO:0007281;organic acid biosynthetic process#GO:0016053;sperm capacitation#GO:0048240;oxoacid metabolic process#GO:0043436;cellular developmental process#GO:0048869;gamete generation#GO:0007276;cellular response to endogenous stimulus#GO:0071495;monocarboxylic acid biosynthetic process#GO:0072330;cellular response to organic substance#GO:0071310;cellular metabolic process#GO:0044237;cell communication#GO:0007154;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;developmental process involved in reproduction#GO:0003006;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;reproduction#GO:0000003;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;sexual reproduction#GO:0019953;multicellular organismal process#GO:0032501;small molecule biosynthetic process#GO:0044283;small molecule metabolic process#GO:0044281;monocarboxylic acid catabolic process#GO:0072329;lipid metabolic process#GO:0006629;signal transduction#GO:0007165;response to organic cyclic compound#GO:0014070;cellular process involved in reproduction in multicellular organism#GO:0022412;cellular response to steroid hormone stimulus#GO:0071383;developmental process#GO:0032502;response to lipid#GO:0033993;spermatid differentiation#GO:0048515;biosynthetic process#GO:0009058;cellular response to lipid#GO:0071396;acylglycerol catabolic process#GO:0046464;cell differentiation#GO:0030154;response to endogenous stimulus#GO:0009719;glycerolipid metabolic process#GO:0046486;cellular response to organic cyclic compound#GO:0071407;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;signaling#GO:0023052;metabolic process#GO:0008152;fatty acid biosynthetic process#GO:0006633;cellular catabolic process#GO:0044248;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;multicellular organism reproduction#GO:0032504;cellular biosynthetic process#GO:0044249;steroid hormone mediated signaling pathway#GO:0043401;organic substance biosynthetic process#GO:1901576;glycerolipid catabolic process#GO:0046503;cellular process#GO:0009987;fatty acid catabolic process#GO:0009062;cell development#GO:0048468;spermatid development#GO:0007286;response to stimulus#GO:0050896;fatty acid metabolic process#GO:0006631;response to hormone#GO:0009725;response to chemical#GO:0042221;biological regulation#GO:0065007;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;response to steroid hormone#GO:0048545 motile cilium#GO:0031514;9+2 motile cilium#GO:0097729;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;cell periphery#GO:0071944;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;cilium#GO:0005929;sperm flagellum#GO:0036126;plasma membrane#GO:0005886 serine protease#PC00203;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000008272.3|UniProtKB=F6QTW3 F6QTW3 PTHR24418:SF421 TYROSINE-PROTEIN KINASE PROTEIN KINASE DOMAIN-CONTAINING PROTEIN protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 non-receptor tyrosine protein kinase#PC00168 CIOIN|Ensembl=ENSCING00000004121.3|UniProtKB=F6XUE2 F6XUE2 LOC100185263 PTHR21402:SF10 GAMETOCYTE SPECIFIC FACTOR 1-RELATED U11_U12 SMALL NUCLEAR RIBONUCLEOPROTEIN 48 KDA PROTEIN CIOIN|Ensembl=ENSCING00000015055.2|UniProtKB=F6S840 F6S840 LOC100183508 PTHR13581:SF5 MRG-BINDING PROTEIN MRG_MORF4L-BINDING PROTEIN regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 histone acetyltransferase complex#GO:0000123;acetyltransferase complex#GO:1902493;chromatin#GO:0000785;protein-DNA complex#GO:0032993;catalytic complex#GO:1902494;NuA4 histone acetyltransferase complex#GO:0035267;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein acetyltransferase complex#GO:0031248;protein-containing complex#GO:0032991;chromosome#GO:0005694 CIOIN|Ensembl=ENSCING00000019360.1|UniProtKB=H2XVK3 H2XVK3 PTHR10306:SF17 SYNAPTOPHYSIN MARVEL DOMAIN-CONTAINING PROTEIN membrane trafficking regulatory protein#PC00151 CIOIN|Ensembl=ENSCING00000007416.3|UniProtKB=F7B8M0 F7B8M0 PTHR13318:SF275 PARTNER OF PAIRED, ISOFORM B-RELATED F-BOX DOMAIN-CONTAINING PROTEIN macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 SCF ubiquitin ligase complex#GO:0019005;intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;cullin-RING ubiquitin ligase complex#GO:0031461;transferase complex#GO:1990234 CIOIN|Ensembl=ENSCING00000008309.3|UniProtKB=F6QBN9 F6QBN9 PTHR43975:SF2 ZGC:101858 EG:BACR7A4.14 PROTEIN-RELATED CIOIN|Ensembl=ENSCING00000004590.3|UniProtKB=F6WPA9 F6WPA9 PTHR13742:SF17 RETINOBLASTOMA-ASSOCIATED PROTEIN RB -RELATED RE32990P-RELATED sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690 cellular developmental process#GO:0048869;negative regulation of biological process#GO:0048519;regulation of mitotic cell cycle phase transition#GO:1901990;negative regulation of cell cycle#GO:0045786;developmental process#GO:0032502;regulation of cell cycle phase transition#GO:1901987;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of mitotic cell cycle#GO:0045930;negative regulation of cell cycle process#GO:0010948;cellular process#GO:0009987;regulation of cell cycle process#GO:0010564;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;negative regulation of mitotic cell cycle phase transition#GO:1901991;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;regulation of G1/S transition of mitotic cell cycle#GO:2000045;negative regulation of cellular process#GO:0048523;regulation of mitotic cell cycle#GO:0007346;regulation of cell cycle G1/S phase transition#GO:1902806;negative regulation of G1/S transition of mitotic cell cycle#GO:2000134 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;chromatin#GO:0000785;protein-DNA complex#GO:0032993;chromosome#GO:0005694;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 CIOIN|Ensembl=ENSCING00000005321.1|UniProtKB=F7BPN8 F7BPN8 PTHR24104:SF57 E3 UBIQUITIN-PROTEIN LIGASE NHLRC1-RELATED BEE-MILK PROTEIN transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein polyubiquitination#GO:0000209;proteasomal protein catabolic process#GO:0010498;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000008953.3|UniProtKB=Q6XZ09 Q6XZ09 LOC445799 PTHR11730:SF60 AMMONIUM TRANSPORTER RH50, ISOFORM D inorganic molecular entity transmembrane transporter activity#GO:0015318;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;inorganic cation transmembrane transporter activity#GO:0022890;channel activity#GO:0015267 localization#GO:0051179;inorganic ion homeostasis#GO:0098771;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;nitrogen compound transport#GO:0071705;homeostatic process#GO:0042592;inorganic ion transmembrane transport#GO:0098660;chemical homeostasis#GO:0048878;cellular process#GO:0009987 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 primary active transporter#PC00068;transporter#PC00227 CIOIN|Ensembl=ENSCING00000006472.3|UniProtKB=F6Q2J9 F6Q2J9 LOC100182755 PTHR11699:SF211 ALDEHYDE DEHYDROGENASE-RELATED ALDEHYDE DEHYDROGENASE FAMILY 16 MEMBER A1 dehydrogenase#PC00092;oxidoreductase#PC00176 5-Hydroxytryptamine degredation#P04372>Aldehyde Dehydrogenase#P04402;Ornithine degradation#P02758>Aminobutyraldehyde dehydrogenase#P03055;Phenylethylamine degradation#P02766>Phenylacetaldehyde dehydrogenase#P03102 CIOIN|Ensembl=ENSCING00000019371.1|UniProtKB=H2XX92 H2XX92 PTHR11933:SF5 TRNA 5-METHYLAMINOMETHYL-2-THIOURIDYLATE -METHYLTRANSFERASE MITOCHONDRIAL TRNA-SPECIFIC 2-THIOURIDYLASE 1 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;tRNA metabolic process#GO:0006399;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;RNA modification#GO:0009451;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;tRNA modification#GO:0006400;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;tRNA wobble uridine modification#GO:0002098;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 RNA metabolism protein#PC00031;RNA methyltransferase#PC00033 CIOIN|Ensembl=ENSCING00000001586.3|UniProtKB=F6VCN7 F6VCN7 PTHR45750:SF3 GH11602P HISTONE ACETYLTRANSFERASE histone modifying activity#GO:0140993;histone acetyltransferase activity#GO:0004402;transferase activity#GO:0016740;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;N-acetyltransferase activity#GO:0008080;acetyltransferase activity#GO:0016407;peptide-lysine-N-acetyltransferase activity#GO:0061733;peptide N-acetyltransferase activity#GO:0034212;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;N-acyltransferase activity#GO:0016410 positive regulation of nitrogen compound metabolic process#GO:0051173;protein-DNA complex organization#GO:0071824;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;regulation of DNA-templated transcription#GO:0006355;cellular component organization#GO:0016043;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA metabolic process#GO:0051252;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;protein-containing complex organization#GO:0043933;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;chromatin organization#GO:0006325;positive regulation of RNA metabolic process#GO:0051254;chromatin remodeling#GO:0006338;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 histone acetyltransferase complex#GO:0000123;acetyltransferase complex#GO:1902493;protein-DNA complex#GO:0032993;catalytic complex#GO:1902494;chromatin#GO:0000785;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein acetyltransferase complex#GO:0031248;protein-containing complex#GO:0032991;chromosome#GO:0005694 Notch signaling pathway#P00045>CoA#P01100 CIOIN|Ensembl=ENSCING00000012860.2|UniProtKB=F6Q0A4 F6Q0A4 PTHR12436:SF3 80 KDA MCM3-ASSOCIATED PROTEIN GERMINAL-CENTER ASSOCIATED NUCLEAR PROTEIN mRNA export from nucleus#GO:0006406;cellular localization#GO:0051641;macromolecule biosynthetic process#GO:0009059;macromolecule localization#GO:0033036;establishment of RNA localization#GO:0051236;macromolecule metabolic process#GO:0043170;transport#GO:0006810;nucleic acid transport#GO:0050657;nitrogen compound transport#GO:0071705;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;mRNA transport#GO:0051028;RNA localization#GO:0006403;localization#GO:0051179;organic substance transport#GO:0071702;nuclear export#GO:0051168;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;RNA transport#GO:0050658;nucleobase-containing compound transport#GO:0015931;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;nuclear transport#GO:0051169;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;transcription export complex 2#GO:0070390;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000007695.3|UniProtKB=F6SJ18 F6SJ18 PTHR46516:SF1 TRNA-SPECIFIC ADENOSINE DEAMINASE 1 TRNA-SPECIFIC ADENOSINE DEAMINASE 1 hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;adenosine deaminase activity#GO:0004000;tRNA-specific adenosine deaminase activity#GO:0008251;deaminase activity#GO:0019239;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 RNA processing factor#PC00147;RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000008221.3|UniProtKB=F6RTW0 F6RTW0 LOC100180836 PTHR11227:SF18 WD-REPEAT PROTEIN INTERACTING WITH PHOSPHOINOSIDES WIPI -RELATED WD REPEAT DOMAIN PHOSPHOINOSITIDE-INTERACTING PROTEIN 3 phosphatidylinositol-3-phosphate binding#GO:0032266;phosphatidylinositol bisphosphate binding#GO:1902936;small molecule binding#GO:0036094;binding#GO:0005488;lipid binding#GO:0008289;phosphatidylinositol binding#GO:0035091;anion binding#GO:0043168;ion binding#GO:0043167;phospholipid binding#GO:0005543;phosphatidylinositol phosphate binding#GO:1901981 cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;macroautophagy#GO:0016236;macromolecule localization#GO:0033036;macromolecule modification#GO:0043412;protein modification process#GO:0036211;autophagy of mitochondrion#GO:0000422;biosynthetic process#GO:0009058;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;cellular component disassembly#GO:0022411;nitrogen compound metabolic process#GO:0006807;catabolic process#GO:0009056;mitochondrion organization#GO:0007005;protein metabolic process#GO:0019538;protein lipidation#GO:0006497;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;cellular component assembly#GO:0022607;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organelle disassembly#GO:1903008;lipoprotein biosynthetic process#GO:0042158;protein localization#GO:0008104;primary metabolic process#GO:0044238;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;organelle organization#GO:0006996;autophagosome assembly#GO:0000045;lipoprotein metabolic process#GO:0042157;autophagy#GO:0006914 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;phagophore assembly site#GO:0000407;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;extrinsic component of membrane#GO:0019898 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000013433.2|UniProtKB=F6V326 F6V326 PTHR22775:SF48 SORTING NEXIN SORTING NEXIN-25 lipid binding#GO:0008289;phosphatidylinositol binding#GO:0035091;phospholipid binding#GO:0005543;binding#GO:0005488 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000007699.3|UniProtKB=F7A2X8 F7A2X8 PTHR10520:SF12 TRIFUNCTIONAL PURINE BIOSYNTHETIC PROTEIN ADENOSINE-3-RELATED TRIFUNCTIONAL PURINE BIOSYNTHETIC PROTEIN ADENOSINE-3 ligase activity#GO:0016874;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase metabolic process#GO:0009112;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;organonitrogen compound biosynthetic process#GO:1901566;purine nucleobase metabolic process#GO:0006144;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 De novo purine biosynthesis#P02738>Phosphoribosylamine glycine ligase#P02908 CIOIN|Ensembl=ENSCING00000007082.3|UniProtKB=F6W9Y0 F6W9Y0 PTHR11596:SF94 ALKALINE PHOSPHATASE ALKALINE PHOSPHATASE hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 cellular metabolic process#GO:0044237;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;dephosphorylation#GO:0016311;metabolic process#GO:0008152 phosphatase#PC00181;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000006125.3|UniProtKB=F6SDC9 F6SDC9 LOC100185123 PTHR11937:SF387 ACTIN ACTIN-LIKE PROTEIN 53D intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 actin and actin related protein#PC00039;cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 Wnt signaling pathway#P00057>NFAT Target Genes#G01559;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>F-actin#P00858;Alzheimer disease-presenilin pathway#P00004>actin#P00114;Integrin signalling pathway#P00034>Actin#P00944;Huntington disease#P00029>Actin#P00807;Nicotinic acetylcholine receptor signaling pathway#P00044>Actin#P01090;Cadherin signaling pathway#P00012>F-actin#P00470;Cytoskeletal regulation by Rho GTPase#P00016>Actin#P00512 CIOIN|Ensembl=ENSCING00000003261.3|UniProtKB=F6Z4U5 F6Z4U5 PTHR20837:SF0 CENTROSOMAL PROTEIN-RELATED COILED-COIL AND C2 DOMAIN-CONTAINING PROTEIN 2A cellular component assembly#GO:0022607;non-motile cilium assembly#GO:1905515;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;cilium assembly#GO:0060271;macromolecule localization#GO:0033036;cell projection organization#GO:0030030;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031;protein localization#GO:0008104;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;protein localization to cilium#GO:0061512;organelle organization#GO:0006996;protein localization to organelle#GO:0033365;plasma membrane bounded cell projection assembly#GO:0120031 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cilium#GO:0005929;ciliary transition zone#GO:0035869 CIOIN|Ensembl=ENSCING00000007996.3|UniProtKB=F6W446 F6W446 PTHR11254:SF395 HECT DOMAIN UBIQUITIN-PROTEIN LIGASE E3 UBIQUITIN-PROTEIN LIGASE SMURF1 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 negative regulation of biological process#GO:0048519;macromolecule modification#GO:0043412;regulation of signaling#GO:0023051;protein catabolic process#GO:0030163;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;post-translational protein modification#GO:0043687;regulation of biological process#GO:0050789;regulation of BMP signaling pathway#GO:0030510;modification-dependent macromolecule catabolic process#GO:0043632;negative regulation of BMP signaling pathway#GO:0030514;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;proteolysis#GO:0006508;regulation of cellular response to growth factor stimulus#GO:0090287;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;negative regulation of cellular process#GO:0048523;proteolysis involved in protein catabolic process#GO:0051603;negative regulation of cell communication#GO:0010648;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of cell communication#GO:0010646;macromolecule catabolic process#GO:0009057;protein ubiquitination#GO:0016567;modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation or removal#GO:0070647;negative regulation of response to stimulus#GO:0048585;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;negative regulation of signaling#GO:0023057;organonitrogen compound metabolic process#GO:1901564;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;regulation of response to stimulus#GO:0048583;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234 SCW signaling pathway#P06216>LACK#P06321;Activin beta signaling pathway#P06210>LACK#P06230;DPP signaling pathway#P06213>LACK#P06278;TGF-beta signaling pathway#P00052>Smurfs#P01279;BMP/activin signaling pathway-drosophila#P06211>Smurf#P06243;ALP23B signaling pathway#P06209>LACK#P06219;DPP-SCW signaling pathway#P06212>LACK#P06269;GBB signaling pathway#P06214>LACK#P06303;MYO signaling pathway#P06215>LACK#P06309 CIOIN|Ensembl=ENSCING00000008526.3|UniProtKB=F7AI93 F7AI93 PTHR15316:SF1 SPLICEOSOME ASSOCIATED PROTEIN 114/SWAP SPLICING FACTOR-RELATED SPLICING FACTOR 3A SUBUNIT 1 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 regulation of nitrogen compound metabolic process#GO:0051171;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of mRNA processing#GO:0050684;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of metabolic process#GO:0019222;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;regulation of cellular metabolic process#GO:0031323;regulation of mRNA metabolic process#GO:1903311 catalytic step 2 spliceosome#GO:0071013;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;U2-type spliceosomal complex#GO:0005684;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;spliceosomal snRNP complex#GO:0097525;small nuclear ribonucleoprotein complex#GO:0030532;protein-containing complex#GO:0032991;U2 snRNP#GO:0005686;U2-type prespliceosome#GO:0071004;membrane-bounded organelle#GO:0043227;Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513 RNA splicing factor#PC00148;RNA processing factor#PC00147;RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000022135.1|UniProtKB=H2XP25 H2XP25 LOC100175287 PTHR19325:SF560 COMPLEMENT COMPONENT-RELATED SUSHI DOMAIN-CONTAINING SUSHI, VON WILLEBRAND FACTOR TYPE A, EGF AND PENTRAXIN DOMAIN-CONTAINING PROTEIN 1 complement component#PC00078 CIOIN|Ensembl=ENSCING00000002183.3|UniProtKB=F6SS40 F6SS40 LOC100178671 PTHR34095:SF1 39S RIBOSOMAL PROTEIN L55, MITOCHONDRIAL LARGE RIBOSOMAL SUBUNIT PROTEIN ML55 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;mitochondrial large ribosomal subunit#GO:0005762;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;mitochondrial ribosome#GO:0005761;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;ribosomal subunit#GO:0044391;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;organellar ribosome#GO:0000313;protein-containing complex#GO:0032991;large ribosomal subunit#GO:0015934;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;ribosome#GO:0005840;mitochondrial protein-containing complex#GO:0098798 ribosomal protein#PC00202;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000023487.1|UniProtKB=H2XN58 H2XN58 PTHR24346:SF75 MAP/MICROTUBULE AFFINITY-REGULATING KINASE AURORA KINASE transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;signaling#GO:0023052 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000012654.2|UniProtKB=F6URT4 F6URT4 LOC100187475 PTHR20990:SF1 PEROXISOMAL BIOGENESIS FACTOR 11 PEROXISOMAL MEMBRANE PROTEIN 11C cellular component organization or biogenesis#GO:0071840;organelle fission#GO:0048285;cellular component organization#GO:0016043;cellular process#GO:0009987;organelle organization#GO:0006996;peroxisome organization#GO:0007031 peroxisomal membrane#GO:0005778;cytoplasm#GO:0005737;bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;microbody#GO:0042579;peroxisome#GO:0005777;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000022601.1|UniProtKB=H2XKX3 H2XKX3 PTHR10697:SF1 MAMMALIAN EPENDYMIN-RELATED PROTEIN 1 MAMMALIAN EPENDYMIN-RELATED PROTEIN 1 cytoplasm#GO:0005737;lysosome#GO:0005764;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;lytic vacuole#GO:0000323;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000006698.3|UniProtKB=F7ARW3 F7ARW3 LOC100176262 PTHR28630:SF3 FAMILY NOT NAMED PEROXIREDOXIN-LIKE 2C CIOIN|Ensembl=ENSCING00000002238.3|UniProtKB=F6YND1 F6YND1 LOC100182231 PTHR11406:SF0 PHOSPHOGLYCERATE KINASE PHOSPHOGLYCERATE KINASE carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;transferase activity#GO:0016740;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;transferase activity, transferring phosphorus-containing groups#GO:0016772;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;anion binding#GO:0043168;kinase activity#GO:0016301;ATP binding#GO:0005524 ribonucleoside triphosphate metabolic process#GO:0009199;nucleoside triphosphate metabolic process#GO:0009141;heterocycle catabolic process#GO:0046700;ribonucleotide catabolic process#GO:0009261;pyridine nucleotide metabolic process#GO:0019362;nucleobase-containing compound metabolic process#GO:0006139;ATP metabolic process#GO:0046034;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;purine ribonucleotide catabolic process#GO:0009154;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;pyridine-containing compound metabolic process#GO:0072524;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;oxoacid metabolic process#GO:0043436;nucleoside phosphate catabolic process#GO:1901292;carbohydrate derivative catabolic process#GO:1901136;purine ribonucleoside triphosphate metabolic process#GO:0009205;generation of precursor metabolites and energy#GO:0006091;cellular metabolic process#GO:0044237;nucleotide catabolic process#GO:0009166;cellular nitrogen compound metabolic process#GO:0034641;nicotinamide nucleotide metabolic process#GO:0046496;nucleoside diphosphate catabolic process#GO:0009134;organic acid metabolic process#GO:0006082;ribonucleotide metabolic process#GO:0009259;monocarboxylic acid metabolic process#GO:0032787;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;organophosphate catabolic process#GO:0046434;hexose biosynthetic process#GO:0019319;glycolytic process#GO:0006096;organophosphate metabolic process#GO:0019637;small molecule biosynthetic process#GO:0044283;nucleobase-containing compound catabolic process#GO:0034655;nucleotide metabolic process#GO:0009117;small molecule metabolic process#GO:0044281;cellular aromatic compound metabolic process#GO:0006725;monosaccharide metabolic process#GO:0005996;carbohydrate derivative metabolic process#GO:1901135;organonitrogen compound catabolic process#GO:1901565;biosynthetic process#GO:0009058;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;purine-containing compound catabolic process#GO:0072523;cellular nitrogen compound catabolic process#GO:0044270;purine nucleotide catabolic process#GO:0006195;organic cyclic compound metabolic process#GO:1901360;carbohydrate catabolic process#GO:0016052;catabolic process#GO:0009056;nucleoside diphosphate metabolic process#GO:0009132;organic substance catabolic process#GO:1901575;carbohydrate metabolic process#GO:0005975;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;carbohydrate biosynthetic process#GO:0016051;heterocycle metabolic process#GO:0046483;organonitrogen compound metabolic process#GO:1901564;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;glucose metabolic process#GO:0006006;aromatic compound catabolic process#GO:0019439;organic cyclic compound catabolic process#GO:1901361;purine nucleoside triphosphate metabolic process#GO:0009144;hexose metabolic process#GO:0019318;carboxylic acid metabolic process#GO:0019752;nucleobase-containing small molecule metabolic process#GO:0055086 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 carbohydrate kinase#PC00065 Glycolysis#P00024>Phosphoglycerate kinase#P00671 CIOIN|Ensembl=ENSCING00000011417.2|UniProtKB=F7AX45 F7AX45 LOC100178283 PTHR10917:SF0 DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC3 DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC3 catalytic activity, acting on RNA#GO:0140098;5'-3' RNA polymerase activity#GO:0034062;transferase activity#GO:0016740;DNA-directed 5'-3' RNA polymerase activity#GO:0003899;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;RNA polymerase activity#GO:0097747;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring phosphorus-containing groups#GO:0016772;RNA polymerase III activity#GO:0001056;RNA polymerase II activity#GO:0001055;RNA polymerase I activity#GO:0001054 membrane-enclosed lumen#GO:0031974;RNA polymerase II, core complex#GO:0005665;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;DNA-directed RNA polymerase complex#GO:0000428;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular protein-containing complex#GO:0140535;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695;RNA polymerase II, holoenzyme#GO:0016591;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;RNA polymerase complex#GO:0030880;protein-containing complex#GO:0032991;RNA polymerase III complex#GO:0005666;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;RNA polymerase I complex#GO:0005736;nuclear protein-containing complex#GO:0140513 RNA metabolism protein#PC00031;DNA-directed RNA polymerase#PC00019 Transcription regulation by bZIP transcription factor#P00055>RNA Polymerase II#P01388;General transcription regulation#P00023>RNA Polymerase II#P00660 CIOIN|Ensembl=ENSCING00000008817.4|UniProtKB=F7BJA3 F7BJA3 LOC100176856 PTHR11246:SF1 PRE-MRNA SPLICING FACTOR PRE-MRNA-PROCESSING FACTOR 6 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;RNA processing#GO:0006396;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;protein-RNA complex assembly#GO:0022618;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;spliceosomal snRNP assembly#GO:0000387;organic substance metabolic process#GO:0071704;mRNA splicing, via spliceosome#GO:0000398;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;protein-containing complex organization#GO:0043933;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;ribonucleoprotein complex biogenesis#GO:0022613;mRNA processing#GO:0006397;protein-RNA complex organization#GO:0071826;RNA splicing, via transesterification reactions#GO:0000375 catalytic step 2 spliceosome#GO:0071013;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;U4/U6 x U5 tri-snRNP complex#GO:0046540;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;spliceosomal snRNP complex#GO:0097525;small nuclear ribonucleoprotein complex#GO:0030532;protein-containing complex#GO:0032991;spliceosomal tri-snRNP complex#GO:0097526;membrane-bounded organelle#GO:0043227;Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513 RNA splicing factor#PC00148;RNA processing factor#PC00147 CIOIN|Ensembl=ENSCING00000021876.1|UniProtKB=H2XR34 H2XR34 PTHR10231:SF66 NUCLEOTIDE-SUGAR TRANSMEMBRANE TRANSPORTER CMP-SIALIC ACID TRANSPORTER carbohydrate derivative transmembrane transporter activity#GO:1901505;nucleobase-containing compound transmembrane transporter activity#GO:0015932;transmembrane transporter activity#GO:0022857;nucleotide-sugar transmembrane transporter activity#GO:0005338;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215 localization#GO:0051179;organic substance transport#GO:0071702;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;organic anion transport#GO:0015711;nucleobase-containing compound transport#GO:0015931;nucleotide-sugar transmembrane transport#GO:0015780;transport#GO:0006810;nitrogen compound transport#GO:0071705;cellular process#GO:0009987;carbohydrate derivative transport#GO:1901264 cytoplasm#GO:0005737;bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;Golgi membrane#GO:0000139;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transporter#PC00227 CIOIN|Ensembl=ENSCING00000005415.3|UniProtKB=F6Z9B3 F6Z9B3 LOC100187490 PTHR11645:SF62 PYRROLINE-5-CARBOXYLATE REDUCTASE PYRROLINE-5-CARBOXYLATE REDUCTASE oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;proteinogenic amino acid metabolic process#GO:0170039;heterocycle metabolic process#GO:0046483;proteinogenic amino acid biosynthetic process#GO:0170038;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;organic cyclic compound metabolic process#GO:1901360;alpha-amino acid biosynthetic process#GO:1901607;nitrogen compound metabolic process#GO:0006807;amino acid biosynthetic process#GO:0008652;alpha-amino acid metabolic process#GO:1901605;small molecule biosynthetic process#GO:0044283;L-amino acid biosynthetic process#GO:0170034;carboxylic acid metabolic process#GO:0019752;L-amino acid metabolic process#GO:0170033;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 reductase#PC00198;oxidoreductase#PC00176 Proline biosynthesis#P02768>Pyrroline-5-carboxylate reductase#P03113 CIOIN|Ensembl=ENSCING00000022441.1|UniProtKB=H2XUG7 H2XUG7 PTHR16146:SF46 INTELECTIN INTELECTIN-1A-RELATED CIOIN|Ensembl=ENSCING00000012825.2|UniProtKB=F6W3C3 F6W3C3 LOC100176778 PTHR13049:SF2 DUF814-RELATED COILED-COIL DOMAIN-CONTAINING PROTEIN 25 CIOIN|Ensembl=ENSCING00000001118.3|UniProtKB=F6VBG8 F6VBG8 PTHR11895:SF7 TRANSAMIDASE GLUTAMYL-TRNA(GLN) AMIDOTRANSFERASE SUBUNIT A, MITOCHONDRIAL metabolite interconversion enzyme#PC00262;ligase#PC00142 CIOIN|Ensembl=ENSCING00000008571.3|UniProtKB=F6WEY7 F6WEY7 PTHR24039:SF49 FIBRILLIN-RELATED SUBFAMILY NOT NAMED extracellular matrix structural protein#PC00103 CIOIN|Ensembl=ENSCING00000008003.3|UniProtKB=A0A1W2WFB7 A0A1W2WFB7 LOC100182865 PTHR23065:SF11 PROLINE-SERINE-THREONINE PHOSPHATASE INTERACTING PROTEIN 1 SYNDAPIN, ISOFORM C lipid binding#GO:0008289;phospholipid binding#GO:0005543;binding#GO:0005488 regulation of endocytosis#GO:0030100;membrane organization#GO:0061024;plasma membrane organization#GO:0007009;endomembrane system organization#GO:0010256;regulation of localization#GO:0032879;regulation of cellular component organization#GO:0051128;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of transport#GO:0051049;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010 cytoplasm#GO:0005737;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 CIOIN|Ensembl=ENSCING00000021265.1|UniProtKB=H2XJV9 H2XJV9 LOC100178010 PTHR28681:SF1 TRANSMEMBRANE PROTEIN 196 TRANSMEMBRANE PROTEIN 196 CIOIN|Ensembl=ENSCING00000009952.3|UniProtKB=F7AJU0 F7AJU0 elf PTHR11849:SF191 ETS ECDYSONE-INDUCED PROTEIN 74EF ISOFORM B transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 PDGF signaling pathway#P00047>Ets#P01167 CIOIN|Ensembl=ENSCING00000014603.2|UniProtKB=F6SY22 F6SY22 PTHR24274:SF1 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 161 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 161 organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cell projection organization#GO:0030030;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;motile cilium#GO:0031514;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cilium#GO:0005929 structural protein#PC00211 CIOIN|Ensembl=ENSCING00000005624.3|UniProtKB=F7ASN6 F7ASN6 LOC100180068 PTHR43238:SF1 GDP-L-FUCOSE SYNTHASE GDP-L-FUCOSE SYNTHASE oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000005090.3|UniProtKB=F6Z2G5 F6Z2G5 PTHR23506:SF23 GH10249P GH10249P secondary carrier transporter#PC00258;transporter#PC00227 Adrenaline and noradrenaline biosynthesis#P00001>VAT1#P00071;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>VAChT#P01078;5HT3 type receptor mediated signaling pathway#P04375>5HT vesicular transporter#P04424;5HT2 type receptor mediated signaling pathway#P04374>5HT vesicular transporter#P04418;Nicotinic acetylcholine receptor signaling pathway#P00044>VAChT#P01089;5HT4 type receptor mediated signaling pathway#P04376>5HT vesicular transporter#P04432;5HT1 type receptor mediated signaling pathway#P04373>5HT vesicular transporter#P04410 CIOIN|Ensembl=ENSCING00000023532.1|UniProtKB=H2Y2G2 H2Y2G2 LOC100185663 PTHR46180:SF1 VINCULIN VINCULIN protein binding#GO:0005515;binding#GO:0005488;beta-catenin binding#GO:0008013 cell adhesion#GO:0007155;cellular process#GO:0009987 cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cell junction#GO:0030054;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;focal adhesion#GO:0005925;cell-substrate junction#GO:0030055;adherens junction#GO:0005912;cell-cell contact zone#GO:0044291;cytoskeleton#GO:0005856;plasma membrane#GO:0005886 Gonadotropin-releasing hormone receptor pathway#P06664>Vinculin#P06771;Integrin signalling pathway#P00034>Vinculin#P00937 CIOIN|Ensembl=ENSCING00000019497.1|UniProtKB=H2Y3G9 H2Y3G9 PTHR12308:SF84 ANOCTAMIN ANOCTAMIN inorganic molecular entity transmembrane transporter activity#GO:0015318;chloride channel activity#GO:0005254;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;chloride transmembrane transporter activity#GO:0015108;monoatomic anion transmembrane transporter activity#GO:0008509;inorganic anion transmembrane transporter activity#GO:0015103;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267;monoatomic ion channel activity#GO:0005216 localization#GO:0051179;inorganic anion transmembrane transport#GO:0098661;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic anion transmembrane transport#GO:0098656;monoatomic ion transmembrane transport#GO:0034220;monoatomic anion transport#GO:0006820;transport#GO:0006810;chloride transport#GO:0006821;chloride transmembrane transport#GO:1902476;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 CIOIN|Ensembl=ENSCING00000008202.3|UniProtKB=F6PJL7 F6PJL7 LOC100178703 PTHR24349:SF514 SERINE/THREONINE-PROTEIN KINASE MAP KINASE-ACTIVATED PROTEIN KINASE 2 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;protein binding#GO:0005515;calmodulin binding#GO:0005516;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular process#GO:0009987;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Ras Pathway#P04393>MAPKAP#P04564;PDGF signaling pathway#P00047>MAPKAPK2#P01157;VEGF signaling pathway#P00056>MAPKAPK2/3#P01415;Angiogenesis#P00005>MAPKAPK2/3#P00244 CIOIN|Ensembl=ENSCING00000020548.1|UniProtKB=F7AEJ9 F7AEJ9 PTHR10869:SF244 PROLYL 4-HYDROXYLASE ALPHA SUBUNIT PROLYL 4-HYDROXYLASE SUBUNIT ALPHA-2 2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;dioxygenase activity#GO:0051213 oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular modified amino acid metabolic process#GO:0006575;protein hydroxylation#GO:0018126;alpha-amino acid metabolic process#GO:1901605;protein metabolic process#GO:0019538;carboxylic acid metabolic process#GO:0019752;L-amino acid metabolic process#GO:0170033;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000020618.1|UniProtKB=F6R6Q8 F6R6Q8 PTHR24377:SF1012 IP01015P-RELATED C2H2-TYPE DOMAIN-CONTAINING PROTEIN-RELATED C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 CIOIN|Ensembl=ENSCING00000019633.1|UniProtKB=H2Y0C0 H2Y0C0 PTHR23245:SF25 TRNA METHYLTRANSFERASE TRNA WYBUTOSINE-SYNTHESIZING PROTEIN 2 HOMOLOG tRNA methyltransferase activity#GO:0008175;catalytic activity, acting on RNA#GO:0140098;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;RNA methyltransferase activity#GO:0008173 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;carbohydrate derivative metabolic process#GO:1901135;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;RNA modification#GO:0009451;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;tRNA modification#GO:0006400;ncRNA metabolic process#GO:0034660;tRNA methylation#GO:0030488;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nucleic acid metabolic process#GO:0090304;methylation#GO:0032259;macromolecule methylation#GO:0043414;RNA methylation#GO:0001510;glycosyl compound metabolic process#GO:1901657 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031;RNA methyltransferase#PC00033 CIOIN|Ensembl=ENSCING00000023270.1|UniProtKB=H2XP49 H2XP49 LOC100175046 PTHR11102:SF147 SEL-1-LIKE PROTEIN SEL1L ADAPTOR SUBUNIT OF ERAD E3 UBIQUITIN LIGASE response to organic substance#GO:0010033;macromolecule catabolic process#GO:0009057;cellular response to stimulus#GO:0051716;response to endoplasmic reticulum stress#GO:0034976;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;response to organonitrogen compound#GO:0010243;ERAD pathway#GO:0036503;cellular process#GO:0009987;primary metabolic process#GO:0044238;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;cellular response to stress#GO:0033554;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000001668.3|UniProtKB=F6XWU5 F6XWU5 LOC100180223 PTHR13774:SF17 PHENAZINE BIOSYNTHESIS PROTEIN PHENAZINE BIOSYNTHESIS-LIKE DOMAIN-CONTAINING PROTEIN isomerase activity#GO:0016853;catalytic activity#GO:0003824 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000008135.3|UniProtKB=F6Y978 F6Y978 PTHR21634:SF9 RE13835P RE13835P protein binding#GO:0005515;protein-folding chaperone binding#GO:0051087;molecular function inhibitor activity#GO:0140678;molecular function regulator activity#GO:0098772;binding#GO:0005488 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000006971.3|UniProtKB=F6SZB5 F6SZB5 LOC100179848 PTHR35263:SF1 TESTIS-EXPRESSED PROTEIN 49 TESTIS-EXPRESSED PROTEIN 49 CIOIN|Ensembl=ENSCING00000008059.3|UniProtKB=F7BCU9 F7BCU9 PTHR14399:SF5 P53-INDUCED PROTEIN RELATED CELL JUNCTION PROTEIN VAB-9 cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987 cell junction#GO:0030054;cellular anatomical entity#GO:0110165;anchoring junction#GO:0070161;cell-cell junction#GO:0005911 CIOIN|Ensembl=ENSCING00000005817.3|UniProtKB=F6WH15 F6WH15 LOC100187034 PTHR10496:SF0 40S RIBOSOMAL PROTEIN S24 40S RIBOSOMAL PROTEIN S24 ribosomal protein#PC00202;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000021517.1|UniProtKB=F7B5V2 F7B5V2 PTHR21724:SF109 SHKT DOMAIN-CONTAINING PROTEIN SHKT DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000008174.3|UniProtKB=F6PNS6 F6PNS6 PTHR11964:SF1 S-ADENOSYLMETHIONINE SYNTHETASE S-ADENOSYLMETHIONINE SYNTHASE transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824 sulfur compound metabolic process#GO:0006790;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 nucleotidyltransferase#PC00174 S-adenosylmethionine biosynthesis#P02773>S-Adenosyl methionine synthetase#P03143 CIOIN|Ensembl=ENSCING00000023512.1|UniProtKB=H2XLA3 H2XLA3 PTHR10288:SF321 KH DOMAIN CONTAINING RNA BINDING PROTEIN MUSHROOM-BODY EXPRESSED, ISOFORM K nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nitrogen compound metabolic process#GO:0051171;regulation of biosynthetic process#GO:0009889;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA metabolic process#GO:0051252;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000009476.3|UniProtKB=F7AEX8 F7AEX8 PTHR34400:SF4 FAMILY NOT NAMED MEMBRANE PROTEIN CIOIN|Ensembl=ENSCING00000006474.3|UniProtKB=F6Q4W5 F6Q4W5 PTHR11610:SF173 LIPASE LIPASE DOMAIN-CONTAINING PROTEIN-RELATED hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;lipid catabolic process#GO:0016042;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;primary metabolic process#GO:0044238 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 lipase#PC00143;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000020806.1|UniProtKB=H2Y3F2 H2Y3F2 PTHR11711:SF30 ADP RIBOSYLATION FACTOR-RELATED ADP-RIBOSYLATION FACTOR 1 carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;anion binding#GO:0043168 cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 G-protein#PC00020 Integrin signalling pathway#P00034>Arf1#P00923;Huntington disease#P00029>ARF#P00786 CIOIN|Ensembl=ENSCING00000007489.3|UniProtKB=Q70VZ3 Q70VZ3 foxE PTHR11829:SF402 FORKHEAD BOX PROTEIN FORK HEAD DOMAIN-CONTAINING PROTEIN FD3-RELATED sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;anatomical structure morphogenesis#GO:0009653;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 CIOIN|Ensembl=ENSCING00000006412.3|UniProtKB=F6QWP6 F6QWP6 LOC100186551 PTHR10739:SF13 CYTIDYLYLTRANSFERASE CHOLINE-PHOSPHATE CYTIDYLYLTRANSFERASE cation binding#GO:0043169;transferase activity#GO:0016740;phosphatidylcholine binding#GO:0031210;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;transferase activity, transferring phosphorus-containing groups#GO:0016772;lipid binding#GO:0008289;ion binding#GO:0043167;phospholipid binding#GO:0005543 transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000006455.3|UniProtKB=F6QKB5 F6QKB5 LOC100177099 PTHR13471:SF0 TETRATRICOPEPTIDE-LIKE HELICAL NUCLEAR EXOSOME REGULATOR NRDE2 negative regulation of gene expression#GO:0010629;negative regulation of cellular metabolic process#GO:0031324;protein-DNA complex organization#GO:0071824;negative regulation of biological process#GO:0048519;regulation of catabolic process#GO:0009894;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;heterochromatin formation#GO:0031507;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulatory ncRNA-mediated gene silencing#GO:0031047;negative regulation of biosynthetic process#GO:0009890;negative regulation of cellular catabolic process#GO:0031330;cellular component organization#GO:0016043;negative regulation of metabolic process#GO:0009892;regulation of cellular catabolic process#GO:0031329;negative regulation of gene expression, epigenetic#GO:0045814;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;epigenetic regulation of gene expression#GO:0040029;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of catabolic process#GO:0009895;regulation of cellular biosynthetic process#GO:0031326;heterochromatin organization#GO:0070828;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;protein-containing complex organization#GO:0043933;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;chromatin organization#GO:0006325;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;chromatin remodeling#GO:0006338;negative regulation of RNA catabolic process#GO:1902369;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 ribonucleoprotein complex#GO:1990904;catalytic step 2 spliceosome#GO:0071013;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000009577.3|UniProtKB=F6TJ64 F6TJ64 LOC100180019 PTHR12826:SF13 RIBONUCLEASE Y RNA-BINDING PROTEIN PNO1 endoribonuclease#PC00094;RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000006394.3|UniProtKB=F6U7M8 F6U7M8 PTHR24173:SF85 ANKYRIN REPEAT CONTAINING PROTEIN FEM-1 HOMOLOG CG6966 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;transferase complex#GO:1990234 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000007928.3|UniProtKB=F7A9X0 F7A9X0 PTHR24348:SF22 SERINE/THREONINE-PROTEIN KINASE UNC-51-RELATED NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular component biogenesis#GO:0044085;regulation of catabolic process#GO:0009894;macroautophagy#GO:0016236;macromolecule modification#GO:0043412;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;nitrogen compound metabolic process#GO:0006807;catabolic process#GO:0009056;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;cellular component assembly#GO:0022607;macromolecule metabolic process#GO:0043170;regulation of autophagy#GO:0010506;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;protein phosphorylation#GO:0006468;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;primary metabolic process#GO:0044238;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;biological regulation#GO:0065007;autophagosome assembly#GO:0000045;peptidyl-serine modification#GO:0018209;autophagy#GO:0006914;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;phagophore assembly site#GO:0000407;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;autophagosome#GO:0005776;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 CIOIN|Ensembl=ENSCING00000006392.3|UniProtKB=F7AX15 F7AX15 PTHR11311:SF16 SPONDIN SPONDIN-1 cell adhesion#GO:0007155;cellular process#GO:0009987 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165 cell adhesion molecule#PC00069 CIOIN|Ensembl=ENSCING00000001755.3|UniProtKB=H2XS52 H2XS52 PTHR15976:SF16 CONSTITUTIVE COACTIVATOR OF PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA ASTEROID DOMAIN-CONTAINING PROTEIN membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000011762.2|UniProtKB=Q4H3V8 Q4H3V8 Ci-ATF4_5 PTHR13044:SF14 ACTIVATING TRANSCRIPTION FACTOR ATF 4/5 CRYPTOCEPHAL, ISOFORM A DNA-binding transcription factor#PC00218 CIOIN|Ensembl=ENSCING00000002337.3|UniProtKB=F6R683 F6R683 LOC100177970 PTHR48030:SF3 SPLICING FACTOR 3B SUBUNIT 4 SPLICING FACTOR 3B SUBUNIT 4 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 positive regulation of gene expression#GO:0010628;positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of mRNA metabolic process#GO:1903313;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;biological regulation#GO:0065007;regulation of mRNA processing#GO:0050684;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of RNA metabolic process#GO:0051254;regulation of mRNA splicing, via spliceosome#GO:0048024;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;precatalytic spliceosome#GO:0071011;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 RNA splicing factor#PC00148;RNA processing factor#PC00147;RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000011436.2|UniProtKB=F7AD61 F7AD61 LOC100175065 PTHR15892:SF2 MITOCHONDRIAL RIBOSOMAL PROTEIN L30 LARGE RIBOSOMAL SUBUNIT PROTEIN UL30M ribosomal protein#PC00202;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000007468.3|UniProtKB=F6YIG0 F6YIG0 PTHR20905:SF1 N-ACETYLTRANSFERASE-RELATED AT07410P-RELATED acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;N-acetyltransferase activity#GO:0008080;acyltransferase activity#GO:0016746;acetyltransferase activity#GO:0016407;catalytic activity#GO:0003824;N-acyltransferase activity#GO:0016410 acetyltransferase#PC00038 CIOIN|Ensembl=ENSCING00000019061.1|UniProtKB=H2XRR7 H2XRR7 PTHR44360:SF1 DNAJ HOMOLOG SUBFAMILY B MEMBER 9 DNAJ HOMOLOG SUBFAMILY B MEMBER 9 protein binding#GO:0005515;protein-folding chaperone binding#GO:0051087;binding#GO:0005488 response to organic substance#GO:0010033;macromolecule catabolic process#GO:0009057;cellular response to stimulus#GO:0051716;response to endoplasmic reticulum stress#GO:0034976;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;response to organonitrogen compound#GO:0010243;ERAD pathway#GO:0036503;cellular process#GO:0009987;primary metabolic process#GO:0044238;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;cellular response to stress#GO:0033554;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chaperone#PC00072 CIOIN|Ensembl=ENSCING00000001582.3|UniProtKB=F6VD75 F6VD75 PTHR13451:SF0 CLASS II CROSSOVER JUNCTION ENDONUCLEASE MUS81 CROSSOVER JUNCTION ENDONUCLEASE MUS81 hydrolase activity, acting on ester bonds#GO:0016788;DNA endonuclease activity#GO:0004520;nuclease activity#GO:0004518;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity#GO:0016787;endonuclease activity#GO:0004519;DNA nuclease activity#GO:0004536;catalytic activity, acting on DNA#GO:0140097 DNA repair#GO:0006281;DNA damage checkpoint signaling#GO:0000077;mitotic cell cycle checkpoint signaling#GO:0007093;nuclear division#GO:0000280;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;cell cycle checkpoint signaling#GO:0000075;DNA damage response#GO:0006974;mitotic cell cycle#GO:0000278;nitrogen compound metabolic process#GO:0006807;recombinational repair#GO:0000725;meiosis I cell cycle process#GO:0061982;reproductive process#GO:0022414;intracellular signal transduction#GO:0035556;meiosis I#GO:0007127;organic substance metabolic process#GO:0071704;negative regulation of cell cycle#GO:0045786;macromolecule metabolic process#GO:0043170;meiotic cell cycle#GO:0051321;regulation of cell cycle phase transition#GO:1901987;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;double-strand break repair via homologous recombination#GO:0000724;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;regulation of cell cycle process#GO:0010564;resolution of meiotic recombination intermediates#GO:0000712;cellular component organization or biogenesis#GO:0071840;response to stress#GO:0006950;reproduction#GO:0000003;regulation of cellular process#GO:0050794;sexual reproduction#GO:0019953;cellular response to stress#GO:0033554;cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;double-strand break repair#GO:0006302;mitotic intra-S DNA damage checkpoint signaling#GO:0031573;cell cycle process#GO:0022402;negative regulation of cell cycle process#GO:0010948;mitotic cell cycle process#GO:1903047;reciprocal homologous recombination#GO:0140527;organic cyclic compound metabolic process#GO:1901360;meiotic cell cycle process#GO:1903046;signal transduction in response to DNA damage#GO:0042770;reciprocal meiotic recombination#GO:0007131;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of mitotic cell cycle#GO:0045930;cellular process#GO:0009987;DNA integrity checkpoint signaling#GO:0031570;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;double-strand break repair via break-induced replication#GO:0000727;organelle organization#GO:0006996;meiotic nuclear division#GO:0140013;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;organelle fission#GO:0048285;mitotic DNA integrity checkpoint signaling#GO:0044774;homologous recombination#GO:0035825;mitotic DNA damage checkpoint signaling#GO:0044773;regulation of mitotic cell cycle#GO:0007346;DNA metabolic process#GO:0006259 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;endonuclease complex#GO:1905348;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000004069.3|UniProtKB=F7B6C9 F7B6C9 LOC100183982 PTHR15606:SF4 DNAJ HOMOLOG SUBFAMILY C MEMBER 8/LIPOPOLYSACCHARIDE SPECIFIC RESPONSE-7-RELATED DNAJ HOMOLOG SUBFAMILY C MEMBER 8 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chaperone#PC00072 CIOIN|Ensembl=ENSCING00000020306.1|UniProtKB=H2XVS8 H2XVS8 LOC100176855 PTHR23408:SF3 METHYLMALONYL-COA MUTASE METHYLMALONIC ACIDURIA TYPE A PROTEIN, MITOCHONDRIAL hydrolase activity#GO:0016787;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 mutase#PC00160 CIOIN|Ensembl=ENSCING00000011415.2|UniProtKB=F7AX55 F7AX55 PTHR11214:SF283 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE N-ACETYLLACTOSAMINIDE BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE 4-LIKE transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;protein O-linked glycosylation#GO:0006493;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 bounding membrane of organelle#GO:0098588;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;Golgi membrane#GO:0000139;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111 CIOIN|Ensembl=ENSCING00000005135.3|UniProtKB=F6VBC2 F6VBC2 PTHR11905:SF159 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN ADAM METALLOPROTEASE metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000013659.2|UniProtKB=F6UB54 F6UB54 LOC100175762 PTHR11035:SF35 VERY-LONG-CHAIN (3R)-3-HYDROXYACYL-COA DEHYDRATASE VERY-LONG-CHAIN (3R)-3-HYDROXYACYL-COA DEHYDRATASE lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835;hydro-lyase activity#GO:0016836;catalytic activity#GO:0003824 organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;monocarboxylic acid biosynthetic process#GO:0072330;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;organic acid metabolic process#GO:0006082;membrane lipid biosynthetic process#GO:0046467;sphingolipid metabolic process#GO:0006665;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;fatty acid metabolic process#GO:0006631;membrane lipid metabolic process#GO:0006643;nitrogen compound metabolic process#GO:0006807;small molecule biosynthetic process#GO:0044283;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;sphingolipid biosynthetic process#GO:0030148;fatty acid biosynthetic process#GO:0006633;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 dehydratase#PC00091;lyase#PC00144 CIOIN|Ensembl=ENSCING00000018824.1|UniProtKB=H2Y279 H2Y279 PTHR10067:SF6 PHOSPHATIDYLSERINE DECARBOXYLASE PHOSPHATIDYLSERINE DECARBOXYLASE PROENZYME, MITOCHONDRIAL lyase activity#GO:0016829;carboxy-lyase activity#GO:0016831;carbon-carbon lyase activity#GO:0016830;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;phospholipid biosynthetic process#GO:0008654;organophosphate biosynthetic process#GO:0090407;glycerolipid biosynthetic process#GO:0045017;cellular metabolic process#GO:0044237;glycerophospholipid metabolic process#GO:0006650;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;phospholipid metabolic process#GO:0006644;lipid biosynthetic process#GO:0008610;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;primary metabolic process#GO:0044238;glycerolipid metabolic process#GO:0046486;glycerophospholipid biosynthetic process#GO:0046474;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 decarboxylase#PC00089 CIOIN|Ensembl=ENSCING00000003567.3|UniProtKB=F6Y8C3 F6Y8C3 PTHR10925:SF5 N-ACETYLTRANSFERASE 10 RNA CYTIDINE ACETYLTRANSFERASE tRNA binding#GO:0000049;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;N-acetyltransferase activity#GO:0008080;acetyltransferase activity#GO:0016407;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;N-acyltransferase activity#GO:0016410 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;RNA modification#GO:0009451;rRNA modification#GO:0000154;RNA processing#GO:0006396;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;ribosome biogenesis#GO:0042254;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;maturation of SSU-rRNA#GO:0030490;ribosomal small subunit biogenesis#GO:0042274 RNA processing factor#PC00147 CIOIN|Ensembl=ENSCING00000007216.3|UniProtKB=F6W790 F6W790 PTHR37412:SF2 C2 DOMAIN-CONTAINING PROTEIN 5 C2 DOMAIN-CONTAINING PROTEIN 5 cation binding#GO:0043169;small molecule binding#GO:0036094;binding#GO:0005488;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;lipid binding#GO:0008289;ion binding#GO:0043167;phospholipid binding#GO:0005543 cellular localization#GO:0051641;intracellular protein transmembrane transport#GO:0065002;positive regulation of organelle organization#GO:0010638;macromolecule localization#GO:0033036;transport#GO:0006810;protein transmembrane transport#GO:0071806;nitrogen compound transport#GO:0071705;regulation of localization#GO:0032879;regulation of cellular component organization#GO:0051128;establishment of protein localization#GO:0045184;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;organic substance transport#GO:0071702;regulation of transport#GO:0051049;establishment of localization#GO:0051234;positive regulation of biological process#GO:0048518;regulation of protein localization#GO:0032880;protein localization to plasma membrane#GO:0072659;localization within membrane#GO:0051668;regulation of transmembrane transport#GO:0034762;positive regulation of establishment of protein localization#GO:1904951;transmembrane transport#GO:0055085;protein localization to membrane#GO:0072657;regulation of protein localization to membrane#GO:1905475;regulation of organelle organization#GO:0033043;positive regulation of transport#GO:0051050;regulation of cellular localization#GO:0060341;cellular process#GO:0009987;protein localization#GO:0008104;positive regulation of cellular process#GO:0048522;localization#GO:0051179;protein localization to cell periphery#GO:1990778;cellular macromolecule localization#GO:0070727;regulation of cellular process#GO:0050794;protein transport#GO:0015031;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;positive regulation of protein localization#GO:1903829;regulation of establishment of protein localization#GO:0070201 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 CIOIN|Ensembl=ENSCING00000006995.3|UniProtKB=F6SAW5 F6SAW5 LOC100177336 PTHR10177:SF401 CYCLINS CYCLIN-O protein kinase regulator activity#GO:0019887;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207 regulation of protein kinase activity#GO:0045859;regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;mitotic cell cycle phase transition#GO:0044772;regulation of nitrogen compound metabolic process#GO:0051171;cell cycle process#GO:0022402;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;cell cycle phase transition#GO:0044770;mitotic cell cycle process#GO:1903047;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;regulation of primary metabolic process#GO:0080090;mitotic cell cycle#GO:0000278;regulation of macromolecule metabolic process#GO:0060255;regulation of molecular function#GO:0065009;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;regulation of protein serine/threonine kinase activity#GO:0071900;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cyclin-dependent protein serine/threonine kinase activity#GO:0000079;regulation of kinase activity#GO:0043549;regulation of cellular metabolic process#GO:0031323 microtubule organizing center#GO:0005815;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;serine/threonine protein kinase complex#GO:1902554;protein kinase complex#GO:1902911;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856 kinase activator#PC00138 CIOIN|Ensembl=ENSCING00000021280.1|UniProtKB=H2XPZ6 H2XPZ6 LOC100176917 PTHR11596:SF94 ALKALINE PHOSPHATASE ALKALINE PHOSPHATASE hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 cellular metabolic process#GO:0044237;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;dephosphorylation#GO:0016311;metabolic process#GO:0008152 phosphatase#PC00181;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000021317.1|UniProtKB=H2XZ20 H2XZ20 PTHR47160:SF5 PUTATIVE-RELATED MULE TRANSPOSASE DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000009812.3|UniProtKB=F6Y5Q3 F6Y5Q3 PTHR11800:SF2 DNA-DIRECTED RNA POLYMERASE DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB3 catalytic activity, acting on RNA#GO:0140098;5'-3' RNA polymerase activity#GO:0034062;transferase activity#GO:0016740;DNA-directed 5'-3' RNA polymerase activity#GO:0003899;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;RNA polymerase activity#GO:0097747;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring phosphorus-containing groups#GO:0016772 RNA metabolism protein#PC00031;DNA-directed RNA polymerase#PC00019 Transcription regulation by bZIP transcription factor#P00055>RNA Polymerase II#P01388;General transcription regulation#P00023>RNA Polymerase II#P00660 CIOIN|Ensembl=ENSCING00000024152.1|UniProtKB=H2Y1T6 H2Y1T6 PTHR19444:SF13 UNC-93 RELATED PROTEIN UNC-93 HOMOLOG A membrane-bound signaling molecule#PC00152 CIOIN|Ensembl=ENSCING00000018970.1|UniProtKB=I6L7H7 I6L7H7 PTHR23245:SF36 TRNA METHYLTRANSFERASE TRNA (GUANINE(37)-N1)-METHYLTRANSFERASE tRNA methyltransferase activity#GO:0008175;catalytic activity, acting on RNA#GO:0140098;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;RNA methyltransferase activity#GO:0008173 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA modification#GO:0009451;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;tRNA modification#GO:0006400;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;macromolecule methylation#GO:0043414;tRNA methylation#GO:0030488;organic cyclic compound metabolic process#GO:1901360;methylation#GO:0032259;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;RNA methylation#GO:0001510;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031;RNA methyltransferase#PC00033 CIOIN|Ensembl=ENSCING00000004507.3|UniProtKB=F7ATE8 F7ATE8 PTHR24403:SF109 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 845-LIKE positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of RNA metabolic process#GO:0051254;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 CIOIN|Ensembl=ENSCING00000022328.1|UniProtKB=H2Y0G7 H2Y0G7 PTHR22902:SF53 SESQUIPEDALIAN INOSITOL PHOSPHATASE INTERACTING PROTEIN, ISOFORM A endosomal transport#GO:0016197;cellular localization#GO:0051641;macromolecule metabolic process#GO:0043170;transport#GO:0006810;endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;cytosolic transport#GO:0016482;retrograde transport, endosome to Golgi#GO:0042147;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;endosome organization#GO:0007032;establishment of localization#GO:0051234;organelle organization#GO:0006996;establishment of localization in cell#GO:0051649;vesicle organization#GO:0016050;intracellular transport#GO:0046907;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 trans-Golgi network#GO:0005802;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;early endosome#GO:0005769;organelle subcompartment#GO:0031984;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;recycling endosome#GO:0055037;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791 membrane traffic protein#PC00150 CIOIN|Ensembl=ENSCING00000003557.3|UniProtKB=F6YTH3 F6YTH3 LOC100177420 PTHR34221:SF4 HYPOTHETICAL PROTEIN LOC691189 CHROMOSOME LG9 OPEN READING FRAME, HUMAN C17ORF98 CIOIN|Ensembl=ENSCING00000001263.3|UniProtKB=F6RED0 F6RED0 LOC100184934 PTHR12922:SF7 UBIQUINONE BIOSYNTHESIS PROTEIN UBIQUINONE BIOSYNTHESIS PROTEIN COQ4 HOMOLOG, MITOCHONDRIAL CIOIN|Ensembl=ENSCING00000007836.3|UniProtKB=C4B8X4 C4B8X4 Ci-RSP4_6 PTHR13159:SF0 RADIAL SPOKEHEAD-RELATED RADIAL SPOKE HEAD 6 HOMOLOG A cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cell projection organization#GO:0030030;microtubule cytoskeleton organization#GO:0000226;microtubule-based movement#GO:0007018;cellular component organization#GO:0016043;axoneme assembly#GO:0035082;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031;cilium movement#GO:0003341;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;microtubule bundle formation#GO:0001578;cytoskeleton organization#GO:0007010;plasma membrane bounded cell projection assembly#GO:0120031 axoneme#GO:0005930;cytoplasmic region#GO:0099568;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;plasma membrane bounded cell projection cytoplasm#GO:0032838;membrane-bounded organelle#GO:0043227;ciliary plasm#GO:0097014;cytoskeleton#GO:0005856;cell projection#GO:0042995;cilium#GO:0005929 cytoskeletal protein#PC00085;microtubule or microtubule-binding cytoskeletal protein#PC00157 CIOIN|Ensembl=ENSCING00000008756.3|UniProtKB=F6T0J5 F6T0J5 LOC100176760 PTHR11599:SF15 PROTEASOME SUBUNIT ALPHA/BETA PROTEASOME SUBUNIT ALPHA TYPE-7-1-RELATED macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 protease#PC00190;protein modifying enzyme#PC00260 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489;Parkinson disease#P00049>20S proteasome#P01227 CIOIN|Ensembl=ENSCING00000002350.3|UniProtKB=Q7YT79 Q7YT79 LOC445702 PTHR24072:SF359 RHO FAMILY GTPASE RAS-RELATED PROTEIN RAC1-RELATED GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;enzyme binding#GO:0019899;ribonucleoside triphosphate phosphatase activity#GO:0017111;kinase binding#GO:0019900;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;protein kinase binding#GO:0019901;anion binding#GO:0043168;ion binding#GO:0043167 establishment or maintenance of cell polarity#GO:0007163;regulation of anatomical structure morphogenesis#GO:0022603;regulation of organelle organization#GO:0033043;regulation of cellular component organization#GO:0051128;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of cytoskeleton organization#GO:0051493;regulation of cell shape#GO:0008360;regulation of biological quality#GO:0065008;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;cortical cytoskeleton organization#GO:0030865;biological regulation#GO:0065007;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;regulation of actin filament-based process#GO:0032970 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 small GTPase#PC00208 T cell activation#P00053>rac#P01324;Huntington disease#P00029>Rac#P00775;Cytoskeletal regulation by Rho GTPase#P00016>Rac#P00523;EGF receptor signaling pathway#P00018>Rac#P00564;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Cdc42#P00834;Ras Pathway#P04393>Rac#P04559;Axon guidance mediated by netrin#P00009>Rac#P00366;Integrin signalling pathway#P00034>Rac#P00927;Axon guidance mediated by Slit/Robo#P00008>Rac#P00354;FGF signaling pathway#P00021>Rac#P00645 CIOIN|Ensembl=ENSCING00000019082.1|UniProtKB=H2XMC6 H2XMC6 PTHR19265:SF0 MEIOSIS-SPECIFIC NUCLEAR STRUCTURAL PROTEIN 1 MEIOSIS-SPECIFIC NUCLEAR STRUCTURAL PROTEIN 1 structural protein#PC00211 CIOIN|Ensembl=ENSCING00000000190.3|UniProtKB=F6WFE5 F6WFE5 PTHR31854:SF2 TUBULIN POLYGLUTAMYLASE COMPLEX SUBUNIT 2 TUBULIN POLYGLUTAMYLASE COMPLEX SUBUNIT 2 microtubule or microtubule-binding cytoskeletal protein#PC00157 CIOIN|Ensembl=ENSCING00000002818.3|UniProtKB=F6WYV6 F6WYV6 PTHR10551:SF9 FASCIN FASCIN-2 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 establishment or maintenance of cell polarity#GO:0007163;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;actin filament bundle assembly#GO:0051017;cell motility#GO:0048870;cellular component organization#GO:0016043;actin filament bundle organization#GO:0061572;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;cell migration#GO:0016477 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165 CIOIN|Ensembl=ENSCING00000019135.1|UniProtKB=H2XLV8 H2XLV8 LOC100177056 PTHR19134:SF562 RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE PROTEIN-TYROSINE-PHOSPHATASE hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;protein tyrosine phosphatase activity#GO:0004725;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 protein phosphatase#PC00195;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000006335.3|UniProtKB=F6PX91 F6PX91 LOC100176657 PTHR12002:SF116 CLAUDIN CLAUDIN-11-LIKE cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cell-cell junction organization#GO:0045216;cellular component biogenesis#GO:0044085;cell-cell junction assembly#GO:0007043;cell junction organization#GO:0034330;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;cell adhesion#GO:0007155;cellular process#GO:0009987 tight junction#GO:0070160;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cell junction#GO:0030054;bicellular tight junction#GO:0005923;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;apical junction complex#GO:0043296;plasma membrane#GO:0005886 cell junction protein#PC00070;tight junction#PC00214 CIOIN|Ensembl=ENSCING00000007987.3|UniProtKB=F6W505 F6W505 PTHR11929:SF145 ALPHA- 1,3 -FUCOSYLTRANSFERASE ALPHA-(1,3)-FUCOSYLTRANSFERASE FUT-1 transferase activity#GO:0016740;fucosyltransferase activity#GO:0008417;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 glycosylation#GO:0070085;metabolic process#GO:0008152 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000001556.3|UniProtKB=H2XLQ1 H2XLQ1 PTHR24028:SF146 CADHERIN-87A CADHERIN 96CB, ISOFORM D-RELATED cell adhesion#GO:0007155;cellular process#GO:0009987 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cell adhesion molecule#PC00069;cadherin#PC00057 CIOIN|Ensembl=ENSCING00000016491.2|UniProtKB=F6YMW5 F6YMW5 LOC113475151 PTHR13396:SF5 NEDD4 FAMILY INTERACTING PROTEIN 1/2 NEDD4 FAMILY INTERACTING PROTEIN positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;transport#GO:0006810;protein catabolic process#GO:0030163;organonitrogen compound catabolic process#GO:1901565;positive regulation of protein modification process#GO:0031401;regulation of biological process#GO:0050789;modification-dependent macromolecule catabolic process#GO:0043632;positive regulation of metabolic process#GO:0009893;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;monoatomic cation transport#GO:0006812;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;positive regulation of biological process#GO:0048518;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;modification-dependent protein catabolic process#GO:0019941;macromolecule catabolic process#GO:0009057;metal ion transport#GO:0030001;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;positive regulation of macromolecule metabolic process#GO:0010604;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;localization#GO:0051179;regulation of primary metabolic process#GO:0080090;positive regulation of protein metabolic process#GO:0051247;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;monoatomic ion transport#GO:0006811;regulation of metabolic process#GO:0019222 cytoplasm#GO:0005737;perinuclear region of cytoplasm#GO:0048471;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000014702.2|UniProtKB=H2Y222 H2Y222 LOC100180038 PTHR11511:SF4 LARVAL STORAGE PROTEIN/PHENOLOXIDASE PHENOLOXIDASE 2-RELATED CIOIN|Ensembl=ENSCING00000019391.1|UniProtKB=H2XXE8 H2XXE8 PTHR24372:SF77 GLYCOPROTEIN HORMONE RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 response to organic substance#GO:0010033;positive regulation of adenylate cyclase activity#GO:0045762;regulation of lyase activity#GO:0051339;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;cellular response to stimulus#GO:0051716;regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;cellular response to endogenous stimulus#GO:0071495;cellular response to chemical stimulus#GO:0070887;positive regulation of catalytic activity#GO:0043085;cellular response to organic substance#GO:0071310;regulation of cyclase activity#GO:0031279;positive regulation of molecular function#GO:0044093;cell communication#GO:0007154;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;positive regulation of cyclase activity#GO:0031281;hormone-mediated signaling pathway#GO:0009755;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to endogenous stimulus#GO:0009719;response to hormone#GO:0009725;cellular response to hormone stimulus#GO:0032870;response to chemical#GO:0042221;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of lyase activity#GO:0051349;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 CIOIN|Ensembl=ENSCING00000002170.3|UniProtKB=F6SSP8 F6SSP8 PTHR17204:SF5 PRE-MRNA PROCESSING PROTEIN PRP39-RELATED PRE-MRNA-PROCESSING FACTOR 39 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;pre-mRNA binding#GO:0036002;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;RNA processing#GO:0006396;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;mRNA cis splicing, via spliceosome#GO:0045292;protein-RNA complex assembly#GO:0022618;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular biosynthetic process#GO:0044249;mRNA splice site recognition#GO:0006376;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;protein-containing complex organization#GO:0043933;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;ribonucleoprotein complex biogenesis#GO:0022613;mRNA processing#GO:0006397;protein-RNA complex organization#GO:0071826;RNA splicing, via transesterification reactions#GO:0000375;spliceosomal complex assembly#GO:0000245 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;U1 snRNP#GO:0005685;U2-type spliceosomal complex#GO:0005684;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;spliceosomal snRNP complex#GO:0097525;small nuclear ribonucleoprotein complex#GO:0030532;protein-containing complex#GO:0032991;U2-type prespliceosome#GO:0071004;membrane-bounded organelle#GO:0043227;Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513 RNA splicing factor#PC00148;RNA processing factor#PC00147;RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000002144.3|UniProtKB=F6W4G0 F6W4G0 LOC100178167 PTHR11785:SF512 AMINO ACID TRANSPORTER SOBREMESA, ISOFORM B L-amino acid transmembrane transporter activity#GO:0015179;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;amino acid transmembrane transporter activity#GO:0015171;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215;organic acid transmembrane transporter activity#GO:0005342 localization#GO:0051179;organic substance transport#GO:0071702;amino acid transmembrane transport#GO:0003333;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;amino acid transport#GO:0006865;organic anion transport#GO:0015711;organic acid transport#GO:0015849;transport#GO:0006810;nitrogen compound transport#GO:0071705;organic acid transmembrane transport#GO:1903825;carboxylic acid transport#GO:0046942;cellular process#GO:0009987;carboxylic acid transmembrane transport#GO:1905039 transporter#PC00227 CIOIN|Ensembl=ENSCING00000007469.3|UniProtKB=F6YIG5 F6YIG5 PTHR19282:SF551 TETRASPANIN RE08073P-RELATED cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000000045.3|UniProtKB=Q4H2Z7 Q4H2Z7 Ci-paraxis-like PTHR23349:SF42 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, TWIST BHLH DOMAIN-CONTAINING PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 basic helix-loop-helix transcription factor#PC00055 CIOIN|Ensembl=ENSCING00000005087.3|UniProtKB=F6Z2Y2 F6Z2Y2 LOC100185078 PTHR13161:SF4 SPLICING FACTOR SUPPRESSOR OF WHITE APRICOT CLK4-ASSOCIATING SERINE_ARGININE RICH PROTEIN RNA splicing factor#PC00148;RNA metabolism protein#PC00031;RNA processing factor#PC00147 CIOIN|Ensembl=ENSCING00000005260.2|UniProtKB=F6V9K6 F6V9K6 PTHR11571:SF222 GLUTATHIONE S-TRANSFERASE GLUTATHIONE TRANSFERASE glutathione transferase activity#GO:0004364;transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824 sulfur compound metabolic process#GO:0006790;nitrogen compound metabolic process#GO:0006807;peptide metabolic process#GO:0006518;cellular modified amino acid metabolic process#GO:0006575;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular process#GO:0009987;glutathione metabolic process#GO:0006749;amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000012751.2|UniProtKB=F6ZR39 F6ZR39 PTHR10704:SF71 CARBOHYDRATE SULFOTRANSFERASE CARBOHYDRATE SULFOTRANSFERASE 1-LIKE sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824 cellular metabolic process#GO:0044237;amino sugar metabolic process#GO:0006040;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000004751.3|UniProtKB=F6PR96 F6PR96 LOC100182043 PTHR23359:SF242 NUCLEOTIDE KINASE GTP:AMP PHOSPHOTRANSFERASE, MITOCHONDRIAL transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;phosphotransferase activity, phosphate group as acceptor#GO:0016776 cellular aromatic compound metabolic process#GO:0006725;nucleoside triphosphate metabolic process#GO:0009141;purine ribonucleoside monophosphate metabolic process#GO:0009167;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;nucleoside monophosphate metabolic process#GO:0009123;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;purine nucleoside monophosphate metabolic process#GO:0009126;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;ribonucleoside monophosphate metabolic process#GO:0009161;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;nucleoside triphosphate biosynthetic process#GO:0009142;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 nucleotide kinase#PC00172;kinase#PC00137 De novo purine biosynthesis#P02738>Adenylate kinase#P02896 CIOIN|Ensembl=ENSCING00000009238.3|UniProtKB=F6W170 F6W170 LOC100183682 PTHR48034:SF21 TRANSFORMER-2 SEX-DETERMINING PROTEIN-RELATED TRANSFORMER-2 PROTEIN HOMOLOG BETA-LIKE ISOFORM X1 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 positive regulation of gene expression#GO:0010628;positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of mRNA metabolic process#GO:1903313;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;biological regulation#GO:0065007;regulation of mRNA processing#GO:0050684;regulation of gene expression#GO:0010468;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule biosynthetic process#GO:0010556;regulation of mRNA splicing, via spliceosome#GO:0048024;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000008047.3|UniProtKB=F6S4X0 F6S4X0 LOC100178759 PTHR15876:SF8 TRANSMEMBRANE PROTEIN ADIPOCYTE-ASSOCIATED 1 TRANSMEMBRANE PROTEIN ADIPOCYTE-ASSOCIATED 1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 CIOIN|Ensembl=ENSCING00000004193.3|UniProtKB=F7B587 F7B587 PTHR45696:SF10 60S ACIDIC RIBOSOMAL PROTEIN P1 LARGE RIBOSOMAL SUBUNIT PROTEIN P1 ribosomal protein#PC00202;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000013464.2|UniProtKB=F6SDU9 F6SDU9 LOC100184864 PTHR45774:SF3 BTB/POZ DOMAIN-CONTAINING BTB (POZ) DOMAIN-CONTAINING 2B-RELATED ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000016259.2|UniProtKB=F6PL73 F6PL73 LOC100181600 PTHR12968:SF1 B9 DOMAIN-CONTAINING B9 DOMAIN-CONTAINING PROTEIN 1 organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cell projection organization#GO:0030030;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031 protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;cilium#GO:0005929;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;ciliary transition zone#GO:0035869 structural protein#PC00211 CIOIN|Ensembl=ENSCING00000003230.3|UniProtKB=F6ZP25 F6ZP25 LOC100184742 PTHR45955:SF1 PHOSPHOACETYLGLUCOSAMINE MUTASE PHOSPHOACETYLGLUCOSAMINE MUTASE isomerase activity#GO:0016853;intramolecular transferase activity#GO:0016866;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;carbohydrate derivative metabolic process#GO:1901135;UDP-N-acetylglucosamine metabolic process#GO:0006047;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleotide-sugar metabolic process#GO:0009225;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing compound biosynthetic process#GO:0034654;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;amino sugar metabolic process#GO:0006040;aromatic compound biosynthetic process#GO:0019438;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 mutase#PC00160 CIOIN|Ensembl=ENSCING00000018925.1|UniProtKB=H2XPI4 H2XPI4 PTHR11849:SF304 ETS DNA-BINDING PROTEIN D-ETS-3 transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 CIOIN|Ensembl=ENSCING00000006417.3|UniProtKB=F6QR08 F6QR08 LOC100178823 PTHR10698:SF0 V-TYPE PROTON ATPASE SUBUNIT H V-TYPE PROTON ATPASE SUBUNIT H ATP synthase#PC00002;primary active transporter#PC00068;transporter#PC00227 CIOIN|Ensembl=ENSCING00000009873.3|UniProtKB=F6Q9J1 F6Q9J1 LOC100182069 PTHR11547:SF57 ARGININE OR CREATINE KINASE PHOSPHAGEN KINASE C-TERMINAL DOMAIN-CONTAINING PROTEIN transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301 organophosphate biosynthetic process#GO:0090407;nitrogen compound metabolic process#GO:0006807;cellular modified amino acid metabolic process#GO:0006575;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;organophosphate metabolic process#GO:0019637;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;metabolic process#GO:0008152;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 amino acid kinase#PC00045 CIOIN|Ensembl=ENSCING00000012452.2|UniProtKB=F6UUF9 F6UUF9 LOC100185726 PTHR46426:SF1 PROTEIN DISULFIDE-ISOMERASE TMX3 PROTEIN DISULFIDE-ISOMERASE TMX3 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chaperone#PC00072 CIOIN|Ensembl=ENSCING00000008565.3|UniProtKB=F6X184 F6X184 PTHR11848:SF33 TGF-BETA FAMILY TGF-BETA FAMILY PROFILE DOMAIN-CONTAINING PROTEIN molecular function activator activity#GO:0140677;binding#GO:0005488;molecular function regulator activity#GO:0098772;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;cytokine activity#GO:0005125;signaling receptor binding#GO:0005102 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cellular response to endogenous stimulus#GO:0071495;regulation of cell population proliferation#GO:0042127;response to growth factor#GO:0070848;cell communication#GO:0007154;transforming growth factor beta receptor signaling pathway#GO:0007179;cellular process#GO:0009987;response to transforming growth factor beta#GO:0071559;cellular response to transforming growth factor beta stimulus#GO:0071560;regulation of biological process#GO:0050789;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;response to stimulus#GO:0050896;response to endogenous stimulus#GO:0009719;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of cellular process#GO:0050794;cellular response to growth factor stimulus#GO:0071363;cell surface receptor signaling pathway#GO:0007166;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007;signaling#GO:0023052 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 growth factor#PC00112 CIOIN|Ensembl=ENSCING00000004797.3|UniProtKB=F6REV8 F6REV8 PTHR13274:SF2 MITOCHONDRIAL RIBOSOMAL PROTEIN S25 SMALL RIBOSOMAL SUBUNIT PROTEIN MS25 ribosomal protein#PC00202;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000009089.3|UniProtKB=F6QE85 F6QE85 LOC100177185 PTHR11461:SF211 SERINE PROTEASE INHIBITOR, SERPIN GH10112P-RELATED protease inhibitor#PC00191 CIOIN|Ensembl=ENSCING00000001992.3|UniProtKB=F6XG01 F6XG01 PTHR22967:SF57 SERINE/THREONINE PROTEIN KINASE AUXILIN, ISOFORM A-RELATED transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000001844.3|UniProtKB=F6T788 F6T788 PTHR19282:SF519 TETRASPANIN TETRASPANIN cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 CIOIN|Gene=RPS13|UniProtKB=Q8I7D6 Q8I7D6 RPS13 PTHR11885:SF6 RIBOSOMAL PROTEIN S15P/S13E SMALL RIBOSOMAL SUBUNIT PROTEIN US15 structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;structural molecule activity#GO:0005198;binding#GO:0005488;organic cyclic compound binding#GO:0097159;rRNA binding#GO:0019843 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic small ribosomal subunit#GO:0022627;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;small ribosomal subunit#GO:0015935;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;ribosomal subunit#GO:0044391 ribosomal protein#PC00202;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000013354.1|UniProtKB=F6RLB9 F6RLB9 LOC100181964 PTHR10500:SF0 BETA-MICROSEMINOPROTEIN SCO-SPONDIN-LIKE intercellular signal molecule#PC00207 CIOIN|Ensembl=ENSCING00000009365.3|UniProtKB=F6WYE6 F6WYE6 LOC100179435 PTHR43818:SF11 BCDNA.GH03377 BCDNA.GH03377 dehydrogenase#PC00092;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000024423.1|UniProtKB=H2XK67 H2XK67 LOC100182652 PTHR24073:SF269 DRAB5-RELATED DNAJ HOMOLOG SUBFAMILY C MEMBER 27 GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824 localization#GO:0051179;organic substance transport#GO:0071702;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;transport#GO:0006810;protein transport#GO:0015031;nitrogen compound transport#GO:0071705;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104 cellular anatomical entity#GO:0110165;endomembrane system#GO:0012505 small GTPase#PC00208;G-protein#PC00020 Integrin signalling pathway#P00034>Rap1#P00906;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Rap1#P00734 CIOIN|Ensembl=ENSCING00000007258.3|UniProtKB=F6VSQ8 F6VSQ8 PTHR46007:SF11 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 12 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 12 molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;transcription coactivator activity#GO:0003713;protein binding#GO:0005515;transcription factor binding#GO:0008134 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of RNA metabolic process#GO:0051254;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;mediator complex#GO:0016592;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031;general transcription factor#PC00259 CIOIN|Ensembl=ENSCING00000009249.3|UniProtKB=F6SNY7 F6SNY7 PTHR23023:SF226 DIMETHYLANILINE MONOOXYGENASE FLAVIN-CONTAINING MONOOXYGENASE oxygenase#PC00177;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000022870.1|UniProtKB=H2Y2F7 H2Y2F7 LOC100185018 PTHR20963:SF8 MULTIPLE INOSITOL POLYPHOSPHATE PHOSPHATASE-RELATED MULTIPLE INOSITOL POLYPHOSPHATE PHOSPHATASE 1 hydrolase#PC00121;phosphatase#PC00181 CIOIN|Ensembl=ENSCING00000012597.2|UniProtKB=F6Y354 F6Y354 LOC100175401 PTHR47537:SF2 CUBILIN CUBILIN cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 CIOIN|Ensembl=ENSCING00000014974.2|UniProtKB=F6UVU7 F6UVU7 LOC100175993 PTHR15129:SF0 SRC-ASSOCIATED ADAPTOR PROTEIN SH3 DOMAIN-CONTAINING PROTEIN cytoplasm#GO:0005737;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000022098.1|UniProtKB=Q4H3J7 Q4H3J7 Ci-FoxA-a PTHR11829:SF380 FORKHEAD BOX PROTEIN PROTEIN FORK HEAD sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;anatomical structure morphogenesis#GO:0009653;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 CIOIN|Ensembl=ENSCING00000005997.3|UniProtKB=F6R9M1 F6R9M1 PTHR19300:SF57 BETA-1,4-GALACTOSYLTRANSFERASE BETA-1,4-N-ACETYLGALACTOSAMINYLTRANSFERASE galactosyltransferase activity#GO:0008378;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 glycosylation#GO:0070085;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000002354.3|UniProtKB=F6PJ70 F6PJ70 PTHR21646:SF76 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 32 cysteine protease#PC00081;protease#PC00190 CIOIN|Ensembl=ENSCING00000007824.3|UniProtKB=F6YS00 F6YS00 nox4 PTHR11972:SF153 NADPH OXIDASE SUPEROXIDE-GENERATING NADPH OXIDASE HEAVY CHAIN SUBUNIT A cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 oxidase#PC00175;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000000405.3|UniProtKB=F6SE21 F6SE21 PTHR24353:SF37 CYCLIC NUCLEOTIDE-DEPENDENT PROTEIN KINASE CAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT PRKX transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 serine/threonine protein kinase complex#GO:1902554;protein kinase complex#GO:1902911;intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;transferase complex#GO:1990234;transferase complex, transferring phosphorus-containing groups#GO:0061695 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Metabotropic glutamate receptor group III pathway#P00039>PKA#P01035;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>PKA#P01075;GABA-B receptor II signaling#P05731>PKA#P05752;5HT1 type receptor mediated signaling pathway#P04373>PKA#P04403;Enkephalin release#P05913>PKA#P05972;Histamine H2 receptor mediated signaling pathway#P04386>PKA#P04491;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PKA#P00862;Dopamine receptor mediated signaling pathway#P05912>PKA#P05946;Beta2 adrenergic receptor signaling pathway#P04378>PKA#P04444;Metabotropic glutamate receptor group II pathway#P00040>PKA#P01050;Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>PKA#P00746;Endothelin signaling pathway#P00019>PKG#P00567;Beta1 adrenergic receptor signaling pathway#P04377>PKA#P04437;Endothelin signaling pathway#P00019>PKA#P00570;Metabotropic glutamate receptor group I pathway#P00041>PKA#P01059 CIOIN|Ensembl=ENSCING00000021229|UniProtKB=Q1RLC9 Q1RLC9 PTHR31148:SF1 U1 SMALL NUCLEAR RIBONUCLEOPROTEIN C U1 SMALL NUCLEAR RIBONUCLEOPROTEIN C nucleic acid binding#GO:0003676;RNA binding#GO:0003723;pre-mRNA binding#GO:0036002;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;RNA processing#GO:0006396;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;mRNA cis splicing, via spliceosome#GO:0045292;protein-RNA complex assembly#GO:0022618;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular biosynthetic process#GO:0044249;mRNA splice site recognition#GO:0006376;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;protein-containing complex organization#GO:0043933;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;ribonucleoprotein complex biogenesis#GO:0022613;mRNA processing#GO:0006397;protein-RNA complex organization#GO:0071826;RNA splicing, via transesterification reactions#GO:0000375;spliceosomal complex assembly#GO:0000245 ribonucleoprotein complex#GO:1990904;spliceosomal snRNP complex#GO:0097525;small nuclear ribonucleoprotein complex#GO:0030532;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;U1 snRNP#GO:0005685;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000009556.3|UniProtKB=F6U805 F6U805 LOC100182510 PTHR36291:SF1 UBAP1-MVB12-ASSOCIATED (UMA)-DOMAIN CONTAINING PROTEIN 1 UBAP1-MVB12-ASSOCIATED (UMA)-DOMAIN CONTAINING PROTEIN 1 CIOIN|Ensembl=ENSCING00000004497.3|UniProtKB=F6TF08 F6TF08 PTHR24300:SF397 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 2U1 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;tetrapyrrole binding#GO:0046906;steroid hydroxylase activity#GO:0008395;oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497;heme binding#GO:0020037 response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;response to chemical#GO:0042221;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 oxygenase#PC00177;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000008030.3|UniProtKB=F6SSA8 F6SSA8 PTHR43689:SF8 HYDROLASE ALPHA_BETA-HYDROLASES SUPERFAMILY PROTEIN serine protease#PC00203 CIOIN|Ensembl=ENSCING00000003629.3|UniProtKB=F6U895 F6U895 LOC100185575 PTHR32289:SF1 PROTEIN FAM167A PROTEIN FAM167A-LIKE CIOIN|Ensembl=ENSCING00000005926.3|UniProtKB=F6WUH0 F6WUH0 LOC100183052 PTHR10884:SF14 NADH DEHYDROGENASE UBIQUINONE IRON-SULFUR PROTEIN 3 NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 3, MITOCHONDRIAL dehydrogenase#PC00092;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000001394.3|UniProtKB=F6ZTS6 F6ZTS6 PTHR11937:SF14 ACTIN ACTIN-RELATED PROTEIN 10 microtubule-based movement#GO:0007018;cellular process#GO:0009987;microtubule-based process#GO:0007017 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 actin and actin related protein#PC00039;cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 CIOIN|Ensembl=ENSCING00000012454.2|UniProtKB=F6UUD7 F6UUD7 LOC100186797 PTHR10334:SF576 CYSTEINE-RICH SECRETORY PROTEIN-RELATED GLI PATHOSIS-RELATED 1-LIKE extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 defense/immunity protein#PC00090 CIOIN|Ensembl=ENSCING00000003959.3|UniProtKB=F6Z255 F6Z255 LOC100185758 PTHR47980:SF23 LD44762P RAB10, MEMBER RAS ONCOGENE FAMILY cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;myosin binding#GO:0017022;binding#GO:0005488 cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;protein secretion#GO:0009306;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;establishment of protein localization to extracellular region#GO:0035592;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;exocytosis#GO:0006887;establishment of localization#GO:0051234;secretion#GO:0046903;protein transport#GO:0015031;protein localization to extracellular region#GO:0071692;export from cell#GO:0140352;secretion by cell#GO:0032940 endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;recycling endosome#GO:0055037;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;secretory vesicle#GO:0099503 TGF-beta signaling pathway#P00052>Ras-GDP#P01291;TGF-beta signaling pathway#P00052>Ras-GTP#P01280 CIOIN|Ensembl=ENSCING00000019118.1|UniProtKB=H2Y397 H2Y397 PTHR18978:SF1 GRIP-1 ASSOCIATED PROTEIN 1 GRIP1-ASSOCIATED PROTEIN 1 endosomal transport#GO:0016197;cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;nitrogen compound transport#GO:0071705;regulation of synapse organization#GO:0050807;regulation of localization#GO:0032879;regulation of cellular component organization#GO:0051128;establishment of protein localization#GO:0045184;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;organic substance transport#GO:0071702;establishment of protein localization to membrane#GO:0090150;endocytic recycling#GO:0032456;regulation of transport#GO:0051049;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;neurotransmitter receptor transport to postsynaptic membrane#GO:0098969;regulation of protein transport#GO:0051223;regulation of postsynaptic membrane neurotransmitter receptor levels#GO:0099072;regulation of protein localization#GO:0032880;protein localization to plasma membrane#GO:0072659;localization within membrane#GO:0051668;vesicle-mediated transport to the plasma membrane#GO:0098876;protein localization to synapse#GO:0035418;protein localization to membrane#GO:0072657;regulation of protein localization to membrane#GO:1905475;vesicle-mediated transport#GO:0016192;regulation of cellular localization#GO:0060341;cellular process#GO:0009987;protein localization#GO:0008104;localization#GO:0051179;protein localization to cell periphery#GO:1990778;cellular macromolecule localization#GO:0070727;regulation of cellular process#GO:0050794;protein localization to cell junction#GO:1902414;protein transport#GO:0015031;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;regulation of synapse structure or activity#GO:0050803;regulation of establishment of protein localization#GO:0070201;protein-containing complex localization#GO:0031503 bounding membrane of organelle#GO:0098588;synapse#GO:0045202;endosome#GO:0005768;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cell junction#GO:0030054;early endosome#GO:0005769;glutamatergic synapse#GO:0098978;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endosome membrane#GO:0010008;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;extrinsic component of membrane#GO:0019898;intracellular anatomical structure#GO:0005622;early endosome membrane#GO:0031901;cytoplasm#GO:0005737;endomembrane system#GO:0012505;recycling endosome#GO:0055037;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;postsynapse#GO:0098794;cytoplasmic vesicle membrane#GO:0030659 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 CIOIN|Ensembl=ENSCING00000007434.3|UniProtKB=F7APL0 F7APL0 LOC100176328 PTHR36978:SF4 P-LOOP CONTAINING NUCLEOTIDE TRIPHOSPHATE HYDROLASE P-LOOP CONTAINING NUCLEOSIDE TRIPHOSPHATE HYDROLASE PROTEIN metabolite interconversion enzyme#PC00262;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000008420.3|UniProtKB=F6X2X2 F6X2X2 LOC100179664 PTHR31698:SF7 LYSOZYME G FAMILY MEMBER PEPTIDASE M15C DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000010224.3|UniProtKB=F6VF47 F6VF47 LOC100186600 PTHR11309:SF126 FRIZZLED FRIZZLED-2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;protein binding#GO:0005515;Wnt-protein binding#GO:0017147;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;non-canonical Wnt signaling pathway#GO:0035567;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;cell-cell signaling by wnt#GO:0198738;canonical Wnt signaling pathway#GO:0060070;cell-cell signaling#GO:0007267;signaling#GO:0023052;Wnt signaling pathway#GO:0016055 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Wnt signaling pathway#P00057>Frizzled#P01428;Cadherin signaling pathway#P00012>Frizzled#P00475;Alzheimer disease-presenilin pathway#P00004>Frizzled#P00119 CIOIN|Ensembl=ENSCING00000005777.3|UniProtKB=F6RSU8 F6RSU8 PTHR11814:SF55 SULFATE TRANSPORTER SODIUM-INDEPENDENT SULFATE ANION TRANSPORTER cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 transporter#PC00227 CIOIN|Ensembl=ENSCING00000009248.3|UniProtKB=F6W0Y5 F6W0Y5 LOC100181350 PTHR11908:SF132 XANTHINE DEHYDROGENASE ALDEHYDE OXIDASE 1-RELATED oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 oxidoreductase#PC00176 Adenine and hypoxanthine salvage pathway#P02723>Xanthine dehydrogenase#P02809;Purine metabolism#P02769>Xanthine Oxidase#P03116 CIOIN|Ensembl=ENSCING00000008625.3|UniProtKB=F6T1X5 F6T1X5 PTHR46237:SF1 CYTOCHROME B5 REDUCTASE 4 FAMILY MEMBER CYTOCHROME B5 REDUCTASE 4 binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor#GO:0016653;tetrapyrrole binding#GO:0046906;oxidoreductase activity, acting on NAD(P)H#GO:0016651;oxidoreductase activity#GO:0016491;heme binding#GO:0020037 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 reductase#PC00198;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000013176.2|UniProtKB=F6Q2A0 F6Q2A0 LOC100186076 PTHR33802:SF1 SI:CH211-161H7.5-RELATED XK-RELATED PROTEIN CIOIN|Ensembl=ENSCING00000004967.3|UniProtKB=A0A1W2WET0 A0A1W2WET0 LOC100185510 PTHR10780:SF18 MITOCHONDRIAL CARRIER HOMOLOG LD43650P mitochondrial carrier protein#PC00158;secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000012402.2|UniProtKB=F6YQ94 F6YQ94 LOC100185809 PTHR12499:SF0 OPTIC ATROPHY 3 PROTEIN OPA3 OPTIC ATROPHY 3 PROTEIN biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of lipid metabolic process#GO:0019216;regulation of metabolic process#GO:0019222 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000015526.2|UniProtKB=F6T860 F6T860 PTHR22802:SF379 C-TYPE LECTIN SUPERFAMILY MEMBER CHONDROITIN SULFATE PROTEOGLYCAN 2 ISOFORM X1 membrane traffic protein#PC00150 CIOIN|Ensembl=ENSCING00000008475.3|UniProtKB=F6T485 F6T485 LOC100177365 PTHR12377:SF0 CYTOSOLIC IRON-SULFUR ASSEMBLY COMPONENT 2B-RELATED CYTOSOLIC IRON-SULFUR ASSEMBLY COMPONENT 2B macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;gene expression#GO:0010467;protein maturation#GO:0051604;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;primary metabolic process#GO:0044238 CIOIN|Ensembl=ENSCING00000015325.2|UniProtKB=F7B7M7 F7B7M7 PTHR47194:SF3 SORTING NEXIN-29-RELATED SORTING NEXIN 29 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000009878.3|UniProtKB=F6WTV6 F6WTV6 LOC100181774 PTHR19353:SF82 FATTY ACID DESATURASE 2 CYTOCHROME B5 HEME-BINDING DOMAIN-CONTAINING PROTEIN oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;organic substance metabolic process#GO:0071704;primary metabolic process#GO:0044238;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;membrane#GO:0016020 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000001979.3|UniProtKB=F6X3S3 F6X3S3 LOC104265927 PTHR10853:SF0 PELOTA PROTEIN PELOTA HOMOLOG negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;heterocycle catabolic process#GO:0046700;RNA metabolic process#GO:0016070;nucleobase-containing compound metabolic process#GO:0006139;cellular nitrogen compound catabolic process#GO:0044270;regulation of biological process#GO:0050789;ncRNA metabolic process#GO:0034660;mRNA metabolic process#GO:0016071;cellular component disassembly#GO:0022411;organic cyclic compound metabolic process#GO:1901360;mRNA catabolic process#GO:0006402;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;organic substance catabolic process#GO:1901575;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;negative regulation of biosynthetic process#GO:0009890;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;nuclear-transcribed mRNA catabolic process#GO:0000956;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organelle disassembly#GO:1903008;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;rRNA metabolic process#GO:0016072;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;nucleobase-containing compound catabolic process#GO:0034655;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 translation release factor#PC00225;translation factor#PC00223;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000006827.3|UniProtKB=F7B065 F7B065 PTHR10736:SF0 BESTROPHIN BESTROPHIN HOMOLOG ion channel#PC00133;transporter#PC00227 CIOIN|Ensembl=ENSCING00000005771.3|UniProtKB=F6RT14 F6RT14 LOC100178270 PTHR14076:SF7 RECEPTOR ACTIVITY MODIFYING PROTEIN RAMP RECEPTOR ACTIVITY-MODIFYING PROTEIN 1-LIKE signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cellular localization#GO:0051641;signal transduction#GO:0007165;macromolecule localization#GO:0033036;receptor internalization#GO:0031623;transport#GO:0006810;nitrogen compound transport#GO:0071705;establishment of protein localization#GO:0045184;calcium ion transport#GO:0006816;regulation of biological process#GO:0050789;organic substance transport#GO:0071702;response to endogenous stimulus#GO:0009719;cellular response to hormone stimulus#GO:0032870;establishment of localization#GO:0051234;monoatomic cation transport#GO:0006812;receptor-mediated endocytosis#GO:0006898;signaling#GO:0023052;response to organic substance#GO:0010033;protein localization to plasma membrane#GO:0072659;localization within membrane#GO:0051668;cellular response to stimulus#GO:0051716;metal ion transport#GO:0030001;cellular response to endogenous stimulus#GO:0071495;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;protein localization to membrane#GO:0072657;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cell communication#GO:0007154;cellular process#GO:0009987;protein localization#GO:0008104;localization#GO:0051179;protein localization to cell periphery#GO:1990778;response to stimulus#GO:0050896;response to hormone#GO:0009725;cellular macromolecule localization#GO:0070727;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;protein transport#GO:0015031;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;monoatomic ion transport#GO:0006811;import into cell#GO:0098657 receptor complex#GO:0043235;cell surface#GO:0009986;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991 transmembrane signal receptor#PC00197 CIOIN|Ensembl=ENSCING00000009047.3|UniProtKB=F6R6K6 F6R6K6 LOC100183968 PTHR12480:SF41 ARGININE DEMETHYLASE AND LYSYL-HYDROXYLASE JMJD JMJC DOMAIN-CONTAINING PROTEIN sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;dioxygenase activity#GO:0051213;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity#GO:0016491 positive regulation of gene expression#GO:0010628;positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of protein metabolic process#GO:0051246;regulation of amide metabolic process#GO:0034248;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;protein modification process#GO:0036211;regulation of cellular component organization#GO:0051128;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;protein hydroxylation#GO:0018126;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;positive regulation of biological process#GO:0048518;positive regulation of translation#GO:0045727;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;regulation of protein-containing complex disassembly#GO:0043244;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;positive regulation of protein metabolic process#GO:0051247;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;post-transcriptional regulation of gene expression#GO:0010608;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;regulation of translation#GO:0006417;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000004925.3|UniProtKB=F7AQR7 F7AQR7 LOC100176841 PTHR10334:SF589 CYSTEINE-RICH SECRETORY PROTEIN-RELATED ANCYLOSTOMA SECRETED PROTEIN ISOFORM X1-RELATED extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 defense/immunity protein#PC00090 CIOIN|Ensembl=ENSCING00000014070.2|UniProtKB=F6QK47 F6QK47 PTHR10334:SF576 CYSTEINE-RICH SECRETORY PROTEIN-RELATED GLI PATHOSIS-RELATED 1-LIKE extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 defense/immunity protein#PC00090 CIOIN|Ensembl=ENSCING00000002481.3|UniProtKB=F7B3K0 F7B3K0 PTHR24056:SF222 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE-LIKE 1 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;phosphorylation#GO:0016310;protein phosphorylation#GO:0006468;cellular process#GO:0009987;protein metabolic process#GO:0019538;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 CIOIN|Ensembl=ENSCING00000007351.3|UniProtKB=F6XXX0 F6XXX0 LOC100177518 PTHR14002:SF54 ENDOGLIN/TGF-BETA RECEPTOR TYPE III ZONA PELLUCIDA SPERM-BINDING PROTEIN 2 transmembrane signal receptor#PC00197 CIOIN|Ensembl=ENSCING00000019069.1|UniProtKB=F7AK90 F7AK90 LOC100179000 PTHR11461:SF211 SERINE PROTEASE INHIBITOR, SERPIN GH10112P-RELATED protease inhibitor#PC00191 CIOIN|Ensembl=ENSCING00000009398.3|UniProtKB=F6UA65 F6UA65 LOC100177491 PTHR10134:SF20 CYTOCHROME B-C1 COMPLEX SUBUNIT RIESKE, MITOCHONDRIAL CYTOCHROME B-C1 COMPLEX SUBUNIT RIESKE, MITOCHONDRIAL-RELATED oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 CIOIN|Ensembl=ENSCING00000019702.1|UniProtKB=H2XUE6 H2XUE6 PTHR45951:SF3 PROTEIN DISPATCHED-RELATED PROTEIN DISPATCHED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;smoothened signaling pathway#GO:0007224;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;membrane#GO:0016020 CIOIN|Ensembl=ENSCING00000008620.3|UniProtKB=F6T1Y9 F6T1Y9 PTHR13391:SF0 MITOCHONDRIAL DISTRIBUTION REGULATOR MISATO PROTEIN MISATO HOMOLOG 1 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000001323.3|UniProtKB=F6W9V3 F6W9V3 LOC100182235 PTHR22802:SF396 C-TYPE LECTIN SUPERFAMILY MEMBER C-TYPE LECTIN DOMAIN-CONTAINING PROTEIN membrane traffic protein#PC00150 CIOIN|Ensembl=ENSCING00000025002.1|UniProtKB=H2Y124 H2Y124 LOC100177635 PTHR21347:SF0 CLEFT LIP AND PALATE ASSOCIATED TRANSMEMBRANE PROTEIN-RELATED LIPID SCRAMBLASE CLPTM1L cellular anatomical entity#GO:0110165;membrane#GO:0016020;endomembrane system#GO:0012505 CIOIN|Ensembl=ENSCING00000025109.1|UniProtKB=H2Y3H8 H2Y3H8 PTHR12429:SF8 NEURALIZED NEURALIZED-LIKE PROTEIN 2 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 Notch signaling pathway#P00045>Neuralized#P01117 CIOIN|Ensembl=ENSCING00000006524.3|UniProtKB=F6PQW9 F6PQW9 zf(fyve)-11 PTHR46275:SF1 HEPATOCYTE GROWTH FACTOR-REGULATED TYROSINE KINASE SUBSTRATE HEPATOCYTE GROWTH FACTOR-REGULATED TYROSINE KINASE SUBSTRATE protein binding#GO:0005515;ubiquitin-like protein binding#GO:0032182;binding#GO:0005488;ubiquitin binding#GO:0043130 endosomal transport#GO:0016197;localization within membrane#GO:0051668;cellular localization#GO:0051641;vesicle-mediated transport to the plasma membrane#GO:0098876;receptor internalization#GO:0031623;transport#GO:0006810;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;localization#GO:0051179;endocytic recycling#GO:0032456;establishment of localization#GO:0051234;establishment of localization in cell#GO:0051649;receptor-mediated endocytosis#GO:0006898;intracellular transport#GO:0046907;import into cell#GO:0098657 cytoplasm#GO:0005737;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular vesicle#GO:0097708;early endosome#GO:0005769;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000014156.2|UniProtKB=F7A8I5 F7A8I5 PTHR24300:SF397 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 2U1 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;tetrapyrrole binding#GO:0046906;steroid hydroxylase activity#GO:0008395;oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497;heme binding#GO:0020037 response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;response to chemical#GO:0042221;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 oxygenase#PC00177;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000008370.3|UniProtKB=F7A172 F7A172 LOC100186763 PTHR23410:SF12 RIBOSOMAL PROTEIN L5-RELATED LARGE RIBOSOMAL SUBUNIT PROTEIN UL18 structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;structural molecule activity#GO:0005198;rRNA binding#GO:0019843;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;cellular process#GO:0009987;ribosomal large subunit biogenesis#GO:0042273;organelle assembly#GO:0070925;protein-RNA complex assembly#GO:0022618;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;organelle organization#GO:0006996;ribosomal large subunit assembly#GO:0000027;ribonucleoprotein complex biogenesis#GO:0022613;protein-RNA complex organization#GO:0071826;ribosome biogenesis#GO:0042254;non-membrane-bounded organelle assembly#GO:0140694 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic large ribosomal subunit#GO:0022625;large ribosomal subunit#GO:0015934;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000005577.3|UniProtKB=F6U472 F6U472 PTHR43086:SF3 VERY-LONG-CHAIN 3-OXOOACYL-COA REDUCTASE NADP-DEPENDENT 3-HYDROXY ACID DEHYDROGENASE YDFG reductase#PC00198;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000003651.3|UniProtKB=F7AXZ4 F7AXZ4 PTHR14963:SF1 RHO GTPASE ACTIVATING PROTEIN 18,19-RELATED RHO GTPASE-ACTIVATING PROTEIN CONUNDRUM nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 regulation of anatomical structure size#GO:0090066;regulation of cell communication#GO:0010646;regulation of actin filament length#GO:0030832;regulation of organelle organization#GO:0033043;regulation of signaling#GO:0023051;regulation of actin filament organization#GO:0110053;regulation of cellular component organization#GO:0051128;cellular component organization#GO:0016043;regulation of actin polymerization or depolymerization#GO:0008064;cellular process#GO:0009987;regulation of intracellular signal transduction#GO:1902531;regulation of actin filament polymerization#GO:0030833;regulation of cellular component size#GO:0032535;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of supramolecular fiber organization#GO:1902903;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of cytoskeleton organization#GO:0051493;regulation of protein-containing complex assembly#GO:0043254;regulation of biological quality#GO:0065008;regulation of cellular process#GO:0050794;regulation of cellular component biogenesis#GO:0044087;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of actin cytoskeleton organization#GO:0032956;regulation of actin filament-based process#GO:0032970;regulation of protein polymerization#GO:0032271 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 GTPase-activating protein#PC00257 CIOIN|Ensembl=ENSCING00000020813.1|UniProtKB=H2XJM4 H2XJM4 PTHR15818:SF2 G PATCH AND KOW-CONTAINING G-PATCH DOMAIN AND KOW MOTIFS-CONTAINING PROTEIN cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA splicing factor#PC00148;RNA processing factor#PC00147;RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000012267.2|UniProtKB=F7AL38 F7AL38 PTHR23509:SF48 PA-PL1 PHOSPHOLIPASE FAMILY INTRACELLULAR PHOSPHOLIPASE A1 hydrolase activity#GO:0016787;lipase activity#GO:0016298;hydrolase activity, acting on ester bonds#GO:0016788;phospholipase activity#GO:0004620;catalytic activity#GO:0003824 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 phospholipase#PC00186;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000024994.1|UniProtKB=H2XKB5 H2XKB5 PTHR22792:SF140 LUPUS LA PROTEIN-RELATED ACHILLES, ISOFORM A nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000016344.2|UniProtKB=F6VH27 F6VH27 PTHR47979:SF53 DRAB11-RELATED FI07418P GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;ion binding#GO:0043167;anion binding#GO:0043168 localization#GO:0051179;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization#GO:0051234;transport#GO:0006810 small GTPase#PC00208 CIOIN|Ensembl=ENSCING00000023567.1|UniProtKB=H2XVU4 H2XVU4 PTHR10877:SF150 POLYCYSTIN FAMILY MEMBER REJ DOMAIN-CONTAINING PROTEIN calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;metal ion transmembrane transporter activity#GO:0046873;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267;monoatomic ion channel activity#GO:0005216 detection of stimulus#GO:0051606;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;detection of mechanical stimulus#GO:0050982;response to mechanical stimulus#GO:0009612;response to abiotic stimulus#GO:0009628 cellular anatomical entity#GO:0110165;membrane#GO:0016020 ion channel#PC00133;transporter#PC00227 CIOIN|Ensembl=ENSCING00000020851.1|UniProtKB=H2XLL1 H2XLL1 LOC100178934 PTHR45570:SF2 CARBOXYLIC ESTER HYDROLASE ACETYLCHOLINESTERASE 1-LIKE metabolite interconversion enzyme#PC00262;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000007485.3|UniProtKB=F6XWH9 F6XWH9 LOC100175259 PTHR11132:SF427 SOLUTE CARRIER FAMILY 35 SOLUTE CARRIER FAMILY 35 MEMBER E1 secondary active transmembrane transporter activity#GO:0015291;antiporter activity#GO:0015297;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 localization#GO:0051179;cellular process#GO:0009987;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000022974.1|UniProtKB=H2XN33 H2XN33 PTHR12620:SF4 U2 SNRNP AUXILIARY FACTOR, SMALL SUBUNIT ZINC FINGER (CCCH TYPE), RNA-BINDING MOTIF AND SERINE_ARGININE RICH 2 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;pre-mRNA binding#GO:0036002;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA splicing factor#PC00148;RNA processing factor#PC00147;RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000020128.1|UniProtKB=F6RR11 F6RR11 PTHR48082:SF2 ATP SYNTHASE SUBUNIT ALPHA, MITOCHONDRIAL ATP SYNTHASE SUBUNIT ALPHA, MITOCHONDRIAL monoatomic cation channel activity#GO:0005261;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;inorganic molecular entity transmembrane transporter activity#GO:0015318;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;proton channel activity#GO:0015252;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;channel activity#GO:0015267;ligase activity#GO:0016874;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;proton transmembrane transporter activity#GO:0015078;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;anion binding#GO:0043168;proton-transporting ATP synthase activity, rotational mechanism#GO:0046933;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;ATP binding#GO:0005524;monoatomic ion transmembrane transporter activity#GO:0015075 cellular aromatic compound metabolic process#GO:0006725;ribonucleoside triphosphate metabolic process#GO:0009199;nucleoside triphosphate metabolic process#GO:0009141;carbohydrate derivative metabolic process#GO:1901135;ATP biosynthetic process#GO:0006754;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ATP metabolic process#GO:0046034;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;purine nucleoside triphosphate biosynthetic process#GO:0009145;heterocycle metabolic process#GO:0046483;purine ribonucleoside triphosphate metabolic process#GO:0009205;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;ribonucleoside triphosphate biosynthetic process#GO:0009201;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;proton motive force-driven ATP synthesis#GO:0015986;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;nucleoside triphosphate biosynthetic process#GO:0009142;organophosphate metabolic process#GO:0019637;purine nucleoside triphosphate metabolic process#GO:0009144;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 ATP synthase#PC00002;primary active transporter#PC00068;transporter#PC00227 ATP synthesis#P02721>F1 alpha#P02791 CIOIN|Ensembl=ENSCING00000005030.3|UniProtKB=F6T9R9 F6T9R9 PTHR20920:SF5 RPE-SPONDIN SMB DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000007229.3|UniProtKB=F6VKE2 F6VKE2 PTHR11616:SF309 SODIUM/CHLORIDE DEPENDENT TRANSPORTER TRANSPORTER metal ion transport#GO:0030001;transmembrane transport#GO:0055085;amino acid transport#GO:0006865;organic anion transport#GO:0015711;organic acid transport#GO:0015849;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;localization#GO:0051179;organic substance transport#GO:0071702;sodium ion transport#GO:0006814;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;sodium ion transmembrane transport#GO:0035725 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 primary active transporter#PC00068;transporter#PC00227 CIOIN|Ensembl=ENSCING00000007617.3|UniProtKB=F6X5M5 F6X5M5 PTHR12280:SF30 PANTOTHENATE KINASE FUMBLE transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301 cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 kinase#PC00137 Coenzyme A biosynthesis#P02736>Pantothenate kinase#P02885 CIOIN|Ensembl=ENSCING00000020788.1|UniProtKB=H2XV35 H2XV35 PTHR11079:SF156 CYTOSINE DEAMINASE FAMILY MEMBER INACTIVE TRNA-SPECIFIC ADENOSINE DEAMINASE-LIKE PROTEIN 3-RELATED hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;adenosine deaminase activity#GO:0004000;tRNA-specific adenosine deaminase activity#GO:0008251;deaminase activity#GO:0019239;catalytic activity#GO:0003824 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 deaminase#PC00088;metabolite interconversion enzyme#PC00262;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000020047.1|UniProtKB=F6QAM3 F6QAM3 LOC100177966 PTHR43735:SF3 APOPTOSIS-INDUCING FACTOR 1 FERROPTOSIS SUPPRESSOR PROTEIN 1 nucleotide binding#GO:0000166;electron transfer activity#GO:0009055;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;flavin adenine dinucleotide binding#GO:0050660;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167;oxidoreductase activity#GO:0016491 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 p53 pathway#P00059>NOXA#G01572 CIOIN|Ensembl=ENSCING00000001911.3|UniProtKB=F7A2K6 F7A2K6 LOC100182976 PTHR11686:SF9 GAMMA GLUTAMYL TRANSPEPTIDASE RE13973P hydrolase activity#GO:0016787;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 sulfur compound metabolic process#GO:0006790;peptide metabolic process#GO:0006518;organonitrogen compound metabolic process#GO:1901564;peptide catabolic process#GO:0043171;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;glutathione metabolic process#GO:0006749;sulfur compound catabolic process#GO:0044273;nitrogen compound metabolic process#GO:0006807;cellular modified amino acid metabolic process#GO:0006575;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 protease#PC00190;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000013026.1|UniProtKB=F6UG00 F6UG00 PTHR19444:SF13 UNC-93 RELATED PROTEIN UNC-93 HOMOLOG A membrane-bound signaling molecule#PC00152 CIOIN|Ensembl=ENSCING00000023010.1|UniProtKB=A0A1W2WGY3 A0A1W2WGY3 LOC100184809 PTHR43607:SF1 V-TYPE PROTON ATPASE CATALYTIC SUBUNIT A H(+)-TRANSPORTING TWO-SECTOR ATPASE inorganic molecular entity transmembrane transporter activity#GO:0015318;transmembrane transporter activity#GO:0022857;primary active transmembrane transporter activity#GO:0015399;ATP-dependent activity#GO:0140657;proton transmembrane transporter activity#GO:0015078;active monoatomic ion transmembrane transporter activity#GO:0022853;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;ATPase-coupled transmembrane transporter activity#GO:0042626;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;inorganic cation transmembrane transporter activity#GO:0022890;active transmembrane transporter activity#GO:0022804;monoatomic ion transmembrane transporter activity#GO:0015075 localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;proton transmembrane transport#GO:1902600;monoatomic ion transmembrane transport#GO:0034220;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;monoatomic cation transport#GO:0006812;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655 ATP synthase#PC00002;primary active transporter#PC00068;transporter#PC00227 CIOIN|Ensembl=ENSCING00000001809.3|UniProtKB=F6WJF4 F6WJF4 PTHR10857:SF106 COPINE C2 DOMAIN-CONTAINING PROTEIN lipid binding#GO:0008289;phospholipid binding#GO:0005543;binding#GO:0005488 response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;cellular process#GO:0009987;response to chemical#GO:0042221 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 calcium-binding protein#PC00060 CIOIN|Ensembl=ENSCING00000006934.3|UniProtKB=F6VNG2 F6VNG2 PTHR10502:SF175 ANNEXIN ANNEXIN A13 lipid binding#GO:0008289;phospholipid binding#GO:0005543;binding#GO:0005488;phosphatidylserine binding#GO:0001786 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;vesicle membrane#GO:0012506;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 calcium-binding protein#PC00060 CIOIN|Ensembl=ENSCING00000001086.3|UniProtKB=F7AZY9 F7AZY9 foxj2 PTHR46078:SF2 FORKHEAD BOX PROTEIN J2 FAMILY MEMBER FORK-HEAD DOMAIN-CONTAINING PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 CIOIN|Ensembl=ENSCING00000003239.4|UniProtKB=F6Z5U4 F6Z5U4 LOC100182540 PTHR12131:SF7 ATP-DEPENDENT RNA AND DNA HELICASE EXOSOME RNA HELICASE MTR4 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;maturation of 5.8S rRNA#GO:0000460;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA metabolism protein#PC00009 CIOIN|Ensembl=ENSCING00000008788.3|UniProtKB=F6V2L0 F6V2L0 PTHR16308:SF13 UBIQUITIN ASSOCIATED PROTEIN 2-LIKE/LINGERER PROTEIN LINGERER CIOIN|Ensembl=ENSCING00000010034.3|UniProtKB=F6QHU8 F6QHU8 PTHR24276:SF98 POLYSERASE-RELATED FI18310P1-RELATED serine protease#PC00203;protease#PC00190 CIOIN|Ensembl=ENSCING00000006103.3|UniProtKB=F6YWW0 F6YWW0 PTHR43591:SF101 METHYLTRANSFERASE METHYLTRANSFERASE-LIKE PROTEIN 27 methyltransferase#PC00155;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000008480.3|UniProtKB=F6T3V6 F6T3V6 PTHR10829:SF23 CORTACTIN AND DREBRIN CORTACTIN, ISOFORM A cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 regulation of anatomical structure size#GO:0090066;regulation of actin filament length#GO:0030832;regulation of organelle organization#GO:0033043;regulation of actin filament organization#GO:0110053;regulation of cellular component organization#GO:0051128;cell motility#GO:0048870;cellular component organization#GO:0016043;regulation of actin polymerization or depolymerization#GO:0008064;cellular process#GO:0009987;regulation of actin filament polymerization#GO:0030833;regulation of cellular component size#GO:0032535;regulation of supramolecular fiber organization#GO:1902903;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of cytoskeleton organization#GO:0051493;regulation of protein-containing complex assembly#GO:0043254;regulation of biological quality#GO:0065008;regulation of cellular process#GO:0050794;regulation of cellular component biogenesis#GO:0044087;biological regulation#GO:0065007;regulation of actin cytoskeleton organization#GO:0032956;regulation of actin filament-based process#GO:0032970;cell migration#GO:0016477;regulation of protein polymerization#GO:0032271 supramolecular complex#GO:0099080;cortical cytoskeleton#GO:0030863;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;cell cortex#GO:0005938;cell periphery#GO:0071944;supramolecular fiber#GO:0099512;cortical actin cytoskeleton#GO:0030864;organelle#GO:0043226;actin filament#GO:0005884;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cytoskeleton#GO:0005856;plasma membrane#GO:0005886;site of polarized growth#GO:0030427 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041;non-motor actin binding protein#PC00165 CIOIN|Ensembl=ENSCING00000004573.3|UniProtKB=A0A1W5BLE2 A0A1W5BLE2 LOC100175515 PTHR10869:SF180 PROLYL 4-HYDROXYLASE ALPHA SUBUNIT FE2OG DIOXYGENASE DOMAIN-CONTAINING PROTEIN 2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;dioxygenase activity#GO:0051213 oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular modified amino acid metabolic process#GO:0006575;protein hydroxylation#GO:0018126;alpha-amino acid metabolic process#GO:1901605;protein metabolic process#GO:0019538;carboxylic acid metabolic process#GO:0019752;L-amino acid metabolic process#GO:0170033;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000002093.3|UniProtKB=F6ZSD7 F6ZSD7 PTHR23192:SF88 OLFACTOMEDIN-RELATED ADHESION G PROTEIN-COUPLED RECEPTOR L2-LIKE regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 structural protein#PC00211 CIOIN|Ensembl=ENSCING00000020340.1|UniProtKB=H2XTM0 H2XTM0 PTHR19325:SF560 COMPLEMENT COMPONENT-RELATED SUSHI DOMAIN-CONTAINING SUSHI, VON WILLEBRAND FACTOR TYPE A, EGF AND PENTRAXIN DOMAIN-CONTAINING PROTEIN 1 complement component#PC00078 CIOIN|Ensembl=ENSCING00000016403.2|UniProtKB=F6S4J4 F6S4J4 PTHR13826:SF14 INTESTINAL TREFOIL FACTOR-RELATED TREFOIL FACTOR 2 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 CIOIN|Ensembl=ENSCING00000010101.3|UniProtKB=F6Z6W8 F6Z6W8 PTHR10983:SF24 1-ACYLGLYCEROL-3-PHOSPHATE ACYLTRANSFERASE-RELATED 1-ACYLGLYCEROL-3-PHOSPHATE O-ACYLTRANSFERASE 3, ISOFORM E-RELATED acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;O-acyltransferase activity#GO:0008374 cellular anatomical entity#GO:0110165;endomembrane system#GO:0012505 acyltransferase#PC00042 CIOIN|Ensembl=ENSCING00000005805.3|UniProtKB=F6RGX9 F6RGX9 LOC100182340 PTHR35156:SF1 TESTIS-EXPRESSED PROTEIN 52 TESTIS-EXPRESSED PROTEIN 52 CIOIN|Gene=nvd-Ci-2|UniProtKB=F7J187 F7J187 nvd-Ci-2 PTHR21266:SF32 IRON-SULFUR DOMAIN CONTAINING PROTEIN CHOLESTEROL 7-DESATURASE NVD oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 oxygenase#PC00177;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000005005.3|UniProtKB=F6WL94 F6WL94 LOC100175194 PTHR11474:SF126 TYROSINASE FAMILY MEMBER TYROSINASE-LIKE PROTEIN TYR-1-RELATED oxygenase#PC00177;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000014914.2|UniProtKB=F6UPI8 F6UPI8 PTHR11829:SF206 FORKHEAD BOX PROTEIN FORKHEAD BOX PROTEIN Q1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;anatomical structure morphogenesis#GO:0009653;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 CIOIN|Ensembl=ENSCING00000011736.2|UniProtKB=F6TX70 F6TX70 PTHR10366:SF853 NAD DEPENDENT EPIMERASE/DEHYDRATASE GH25466P oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 dehydratase#PC00091;lyase#PC00144 CIOIN|Ensembl=ENSCING00000010145.3|UniProtKB=F6PI53 F6PI53 LOC100178005 PTHR11644:SF2 CYTIDINE DEAMINASE CYTIDINE DEAMINASE cation binding#GO:0043169;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;small molecule binding#GO:0036094;zinc ion binding#GO:0008270;binding#GO:0005488;catalytic activity#GO:0003824;transition metal ion binding#GO:0046914;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;metal ion binding#GO:0046872;deaminase activity#GO:0019239;ion binding#GO:0043167 cellular aromatic compound metabolic process#GO:0006725;nucleoside metabolic process#GO:0009116;glycosyl compound catabolic process#GO:1901658;carbohydrate derivative metabolic process#GO:1901135;heterocycle catabolic process#GO:0046700;pyrimidine-containing compound metabolic process#GO:0072527;organonitrogen compound catabolic process#GO:1901565;nucleobase-containing compound metabolic process#GO:0006139;cellular nitrogen compound catabolic process#GO:0044270;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;catabolic process#GO:0009056;nucleoside catabolic process#GO:0009164;organic substance catabolic process#GO:1901575;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248;heterocycle metabolic process#GO:0046483;carbohydrate derivative catabolic process#GO:1901136;cellular metabolic process#GO:0044237;organonitrogen compound metabolic process#GO:1901564;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;small molecule catabolic process#GO:0044282;aromatic compound catabolic process#GO:0019439;nucleobase-containing small molecule catabolic process#GO:0034656;organic cyclic compound catabolic process#GO:1901361;nucleobase-containing compound catabolic process#GO:0034655;glycosyl compound metabolic process#GO:1901657;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 deaminase#PC00088;hydrolase#PC00121 Salvage pyrimidine ribonucleotides#P02775>Cytidine deaminase#P03154;Salvage pyrimidine deoxyribonucleotides#P02774>Cytidine deaminase#P03144;Pyrimidine Metabolism#P02771>Cytidine Deaminase#P03130 CIOIN|Ensembl=ENSCING00000000098.3|UniProtKB=F6T5Q1 F6T5Q1 LOC100184425 PTHR11571:SF224 GLUTATHIONE S-TRANSFERASE HEMATOPOIETIC PROSTAGLANDIN D SYNTHASE glutathione transferase activity#GO:0004364;transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824 sulfur compound metabolic process#GO:0006790;nitrogen compound metabolic process#GO:0006807;peptide metabolic process#GO:0006518;cellular modified amino acid metabolic process#GO:0006575;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular process#GO:0009987;glutathione metabolic process#GO:0006749;amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000021765.1|UniProtKB=H2Y0G4 H2Y0G4 PTHR11959:SF10 4-HYDROXYPHENYLPYRUVATE DIOXYGENASE 4-HYDROXYPHENYLPYRUVATE DIOXYGENASE-LIKE PROTEIN oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;dioxygenase activity#GO:0051213 cellular aromatic compound metabolic process#GO:0006725;oxoacid metabolic process#GO:0043436;tyrosine metabolic process#GO:0006570;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;aromatic compound catabolic process#GO:0019439;aromatic amino acid metabolic process#GO:0009072;organic cyclic compound metabolic process#GO:1901360;small molecule catabolic process#GO:0044282;nitrogen compound metabolic process#GO:0006807;alpha-amino acid metabolic process#GO:1901605;organic cyclic compound catabolic process#GO:1901361;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;carboxylic acid metabolic process#GO:0019752;aromatic amino acid family catabolic process#GO:0009074;amino acid metabolic process#GO:0006520;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 oxygenase#PC00177;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000008776.3|UniProtKB=F6SDH3 F6SDH3 PTHR24039:SF57 FIBRILLIN-RELATED FIBROPELLIN-2 extracellular matrix structural protein#PC00103 CIOIN|Ensembl=ENSCING00000004429.3|UniProtKB=F6Y403 F6Y403 LOC100176903 PTHR11802:SF201 SERINE PROTEASE FAMILY S10 SERINE CARBOXYPEPTIDASE CARBOXYPEPTIDASE hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171;carboxypeptidase activity#GO:0004180 serine protease#PC00203;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000014500.2|UniProtKB=F6QAV6 F6QAV6 LOC100181425 PTHR12483:SF115 SOLUTE CARRIER FAMILY 31 COPPER TRANSPORTERS COPPER TRANSPORT PROTEIN secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000009235.3|UniProtKB=F6W1E1 F6W1E1 LOC100181281 PTHR31183:SF1 TRICHOPLEIN KERATIN FILAMENT-BINDING PROTEIN FAMILY MEMBER CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 53 structural protein#PC00211 CIOIN|Ensembl=ENSCING00000005993.3|UniProtKB=F6V5C3 F6V5C3 PTHR23320:SF158 MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MS4A -RELATED CREB-BINDING PROTEIN-LIKE ISOFORM X1 transporter#PC00227 CIOIN|Ensembl=ENSCING00000021377.1|UniProtKB=H2Y2X6 H2Y2X6 LOC100183896 PTHR43011:SF1 IRON-SULFUR CLUSTER ASSEMBLY 2 HOMOLOG, MITOCHONDRIAL IRON-SULFUR CLUSTER ASSEMBLY 2 HOMOLOG, MITOCHONDRIAL cation binding#GO:0043169;small molecule binding#GO:0036094;binding#GO:0005488;iron-sulfur cluster binding#GO:0051536;iron ion binding#GO:0005506;transition metal ion binding#GO:0046914;metal ion binding#GO:0046872;ion binding#GO:0043167 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;iron-sulfur cluster assembly#GO:0016226;cellular component organization#GO:0016043;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 CIOIN|Ensembl=ENSCING00000002693.3|UniProtKB=F6X1K6 F6X1K6 PTHR12241:SF31 TUBULIN POLYGLUTAMYLASE POLYGLUTAMYLASE COMPLEX SUBUNIT TTLL1 cytoskeletal protein binding#GO:0008092;ligase activity#GO:0016874;protein binding#GO:0005515;tubulin binding#GO:0015631;catalytic activity, acting on a protein#GO:0140096;binding#GO:0005488;catalytic activity#GO:0003824 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;microtubule cytoskeleton organization#GO:0000226;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;cellular component organization#GO:0016043;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;nitrogen compound metabolic process#GO:0006807;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;microtubule cytoskeleton#GO:0015630;ciliary basal body#GO:0036064;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;cilium#GO:0005929;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;microtubule or microtubule-binding cytoskeletal protein#PC00157 CIOIN|Ensembl=ENSCING00000001558.3|UniProtKB=F6XZ52 F6XZ52 LOC100181412 PTHR42940:SF3 ALCOHOL DEHYDROGENASE 1-RELATED ALCOHOL DEHYDROGENASE 1-RELATED oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000002179.3|UniProtKB=Q4H3N0 Q4H3N0 Ci-ELK PTHR11849:SF133 ETS ETS DOMAIN-CONTAINING PROTEIN transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>ELK#P00890;Parkinson disease#P00049>Elk-1#P01233 CIOIN|Ensembl=ENSCING00000014221.2|UniProtKB=F6Y0X5 F6Y0X5 LOC100176136 PTHR19282:SF519 TETRASPANIN TETRASPANIN cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000022603.1|UniProtKB=F6QJJ5 F6QJJ5 PTHR24412:SF497 KELCH PROTEIN KELCH-LIKE PROTEIN 18 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000005186.3|UniProtKB=F7B6K5 F7B6K5 PTHR13252:SF9 F-BOX ONLY PROTEIN 28 F-BOX ONLY PROTEIN 28 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein polyubiquitination#GO:0000209;post-translational protein modification#GO:0043687;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;organic substance metabolic process#GO:0071704;primary metabolic process#GO:0044238;metabolic process#GO:0008152 CIOIN|Ensembl=ENSCING00000012406.2|UniProtKB=F6YFV6 F6YFV6 PTHR10003:SF86 SUPEROXIDE DISMUTASE CU-ZN -RELATED COPPER CHAPERONE FOR SUPEROXIDE DISMUTASE cation binding#GO:0043169;antioxidant activity#GO:0016209;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;transition metal ion binding#GO:0046914;copper ion binding#GO:0005507;metal ion binding#GO:0046872;ion binding#GO:0043167;oxidoreductase activity#GO:0016491 cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;cellular metabolic process#GO:0044237;response to oxidative stress#GO:0006979;cellular process#GO:0009987;response to stimulus#GO:0050896;cellular response to oxygen-containing compound#GO:1901701;detoxification#GO:0098754;response to stress#GO:0006950;response to chemical#GO:0042221;cellular response to oxidative stress#GO:0034599;response to toxic substance#GO:0009636;response to reactive oxygen species#GO:0000302;cellular response to stress#GO:0033554;metabolic process#GO:0008152 oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000017997.1|UniProtKB=H2XU36 H2XU36 LOC100181677 PTHR19134:SF527 RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 7 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;protein tyrosine phosphatase activity#GO:0004725;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 protein phosphatase#PC00195;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000007245.3|UniProtKB=F6U7R9 F6U7R9 PTHR43520:SF8 ATP7, ISOFORM B P-TYPE CU(+) TRANSPORTER inorganic molecular entity transmembrane transporter activity#GO:0015318;small molecule binding#GO:0036094;binding#GO:0005488;transition metal ion binding#GO:0046914;copper ion binding#GO:0005507;metal ion binding#GO:0046872;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;P-type ion transporter activity#GO:0015662;ATPase-coupled transmembrane transporter activity#GO:0042626;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;active transmembrane transporter activity#GO:0022804;cation binding#GO:0043169;transmembrane transporter activity#GO:0022857;primary active transmembrane transporter activity#GO:0015399;ATP-dependent activity#GO:0140657;metal ion transmembrane transporter activity#GO:0046873;active monoatomic ion transmembrane transporter activity#GO:0022853;ion binding#GO:0043167;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion transmembrane transporter activity#GO:0015075 monoatomic cation homeostasis#GO:0055080;homeostatic process#GO:0042592;inorganic ion homeostasis#GO:0098771;chemical homeostasis#GO:0048878;monoatomic ion homeostasis#GO:0050801 cellular anatomical entity#GO:0110165;membrane#GO:0016020 primary active transporter#PC00068;transporter#PC00227 CIOIN|Ensembl=ENSCING00000004937.3|UniProtKB=F7A606 F7A606 PTHR22904:SF523 TPR REPEAT CONTAINING PROTEIN STRESS-INDUCED-PHOSPHOPROTEIN 1 heat shock protein binding#GO:0031072;protein binding#GO:0005515;binding#GO:0005488;Hsp90 protein binding#GO:0051879 CIOIN|Ensembl=ENSCING00000003155.3|UniProtKB=F6QEE6 F6QEE6 PTHR12670:SF1 CERAMIDASE NEUTRAL CERAMIDASE hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;alcohol biosynthetic process#GO:0046165;organonitrogen compound catabolic process#GO:1901565;organic hydroxy compound biosynthetic process#GO:1901617;lipid catabolic process#GO:0016042;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;sphingolipid metabolic process#GO:0006665;carboxylic acid biosynthetic process#GO:0046394;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;sphingolipid catabolic process#GO:0030149;cellular lipid catabolic process#GO:0044242;amide metabolic process#GO:0043603;sphingolipid biosynthetic process#GO:0030148;fatty acid biosynthetic process#GO:0006633;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;long-chain fatty acid metabolic process#GO:0001676;organic hydroxy compound metabolic process#GO:1901615;organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;monocarboxylic acid biosynthetic process#GO:0072330;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;alcohol metabolic process#GO:0006066;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;membrane lipid biosynthetic process#GO:0046467;monocarboxylic acid metabolic process#GO:0032787;ceramide metabolic process#GO:0006672;primary metabolic process#GO:0044238;fatty acid metabolic process#GO:0006631;membrane lipid metabolic process#GO:0006643;small molecule biosynthetic process#GO:0044283;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281 cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 CIOIN|Ensembl=ENSCING00000015377.2|UniProtKB=F6WH30 F6WH30 LOC100175261 PTHR11984:SF53 CONNEXIN GAP JUNCTION PROTEIN wide pore channel activity#GO:0022829;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;channel activity#GO:0015267 biological regulation#GO:0065007;regulation of biological process#GO:0050789;cell communication#GO:0007154;cellular process#GO:0009987;cell-cell signaling#GO:0007267;signaling#GO:0023052 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 cell junction protein#PC00070;gap junction#PC00105 CIOIN|Ensembl=ENSCING00000007761.3|UniProtKB=F6XTS5 F6XTS5 PTHR24256:SF571 TRYPTASE-RELATED PEPTIDASE S1 DOMAIN-CONTAINING PROTEIN hydrolase activity#GO:0016787;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 serine protease#PC00203;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000006890.3|UniProtKB=F6YTZ8 F6YTZ8 PTHR45632:SF10 LD33804P BTB DOMAIN-CONTAINING PROTEIN scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000002821.3|UniProtKB=F6WZ78 F6WZ78 LOC100178698 PTHR36978:SF4 P-LOOP CONTAINING NUCLEOTIDE TRIPHOSPHATE HYDROLASE P-LOOP CONTAINING NUCLEOSIDE TRIPHOSPHATE HYDROLASE PROTEIN metabolite interconversion enzyme#PC00262;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000001961.3|UniProtKB=F6XT02 F6XT02 ci-arfgap-2 PTHR45705:SF1 FI20236P1 FI20236P1 nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047;GTPase regulator activity#GO:0030695;molecular function activator activity#GO:0140677;GTPase activator activity#GO:0005096;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000013191.2|UniProtKB=F6VTS4 F6VTS4 LOC100179418 PTHR11461:SF211 SERINE PROTEASE INHIBITOR, SERPIN GH10112P-RELATED protease inhibitor#PC00191 CIOIN|Ensembl=ENSCING00000022313.1|UniProtKB=H2XYU0 H2XYU0 PTHR11082:SF5 TRNA-DIHYDROURIDINE SYNTHASE TRNA-DIHYDROURIDINE(16_17) SYNTHASE [NAD(P)(+)]-LIKE catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on RNA#GO:0140098;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor#GO:0016628 RNA processing factor#PC00147 CIOIN|Ensembl=ENSCING00000013358.2|UniProtKB=F6YWQ8 F6YWQ8 PTHR45739:SF11 MATRIX PROTEIN, PUTATIVE-RELATED FRAS1-RELATED EXTRACELLULAR MATRIX PROTEIN 1-LIKE ISOFORM X1 anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;developmental process#GO:0032502 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165 CIOIN|Ensembl=ENSCING00000022500.1|UniProtKB=H2Y0T8 H2Y0T8 PTHR19143:SF458 FIBRINOGEN/TENASCIN/ANGIOPOEITIN FIBRINOGEN C-TERMINAL DOMAIN-CONTAINING PROTEIN-RELATED external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 CIOIN|Ensembl=ENSCING00000020076.1|UniProtKB=H2XXA0 H2XXA0 PTHR14309:SF12 EXPRESSED PROTEIN PH DOMAIN-CONTAINING PROTEIN biological regulation#GO:0065007;regulation of biological process#GO:0050789;regulation of cell differentiation#GO:0045595;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794 cellular anatomical entity#GO:0110165;membrane#GO:0016020 CIOIN|Ensembl=ENSCING00000016959.2|UniProtKB=F6RPK0 F6RPK0 PTHR43115:SF4 DEHYDROGENASE/REDUCTASE SDR FAMILY MEMBER 11 DEHYDROGENASE_REDUCTASE SDR FAMILY MEMBER 11 oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000003858.3|UniProtKB=F6TXF8 F6TXF8 PTHR11388:SF100 ORGANIC ANION TRANSPORTER SOLUTE CARRIER ORGANIC ANION TRANSPORTER FAMILY MEMBER 4A1 transporter#PC00227 CIOIN|Ensembl=ENSCING00000001033.3|UniProtKB=F6VEF4 F6VEF4 PTHR24034:SF205 EGF-LIKE DOMAIN-CONTAINING PROTEIN NIDOGEN extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 CIOIN|Ensembl=ENSCING00000014385.2|UniProtKB=F6SVN8 F6SVN8 PTHR11579:SF0 PROTEIN-L-ISOASPARTATE O-METHYLTRANSFERASE PROTEIN-L-ISOASPARTATE(D-ASPARTATE) O-METHYLTRANSFERASE transferase activity#GO:0016740;O-methyltransferase activity#GO:0008171;catalytic activity#GO:0003824;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a protein#GO:0140096;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;protein methyltransferase activity#GO:0008276 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 methyltransferase#PC00155 CIOIN|Ensembl=ENSCING00000002977.3|UniProtKB=Q4H3U1 Q4H3U1 Ci-BTF3 PTHR10351:SF23 TRANSCRIPTION FACTOR BTF3 FAMILY MEMBER TRANSCRIPTION FACTOR BTF3 cytoplasm#GO:0005737;cytosol#GO:0005829;protein-containing complex#GO:0032991;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 CIOIN|Ensembl=ENSCING00000001741.3|UniProtKB=F7AMQ2 F7AMQ2 PTHR21405:SF0 CDNA SEQUENCE BC021608 TETRATRICOPEPTIDE REPEAT PROTEIN 36 CIOIN|Ensembl=ENSCING00000003559.3|UniProtKB=F6YSZ2 F6YSZ2 PTHR15427:SF33 EMILIN ELASTIN MICROFIBRIL INTERFACE-LOCATED PROTEIN ELASTIN MICROFIBRIL INTERFACER COLLAGEN IV NC1 DOMAIN-CONTAINING PROTEIN scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000016977.2|UniProtKB=F7BK02 F7BK02 LOC100184275 PTHR21392:SF0 TRNA-URIDINE AMINOCARBOXYPROPYLTRANSFERASE 2 TRNA-URIDINE AMINOCARBOXYPROPYLTRANSFERASE 2 CIOIN|Ensembl=ENSCING00000005289.3|UniProtKB=F6VRW9 F6VRW9 PTHR23233:SF84 SAL-LIKE PROTEIN FI23031P1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 CIOIN|Ensembl=ENSCING00000011588.2|UniProtKB=F6S277 F6S277 LOC100178653 PTHR11571:SF222 GLUTATHIONE S-TRANSFERASE GLUTATHIONE TRANSFERASE glutathione transferase activity#GO:0004364;transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824 sulfur compound metabolic process#GO:0006790;nitrogen compound metabolic process#GO:0006807;peptide metabolic process#GO:0006518;cellular modified amino acid metabolic process#GO:0006575;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular process#GO:0009987;glutathione metabolic process#GO:0006749;amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000000837.3|UniProtKB=F6R180 F6R180 LOC100182469 PTHR13016:SF0 AMMECR1 HOMOLOG AMME SYNDROME CANDIDATE GENE 1 PROTEIN CIOIN|Ensembl=ENSCING00000003608.3|UniProtKB=F6U9D1 F6U9D1 LOC100180777 PTHR31968:SF4 SERINE/ARGININE-RELATED PROTEIN 53 SERINE_ARGININE-RELATED PROTEIN 53 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;alternative mRNA splicing, via spliceosome#GO:0000380;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000020072.1|UniProtKB=H2XPC3 H2XPC3 PTHR22802:SF379 C-TYPE LECTIN SUPERFAMILY MEMBER CHONDROITIN SULFATE PROTEOGLYCAN 2 ISOFORM X1 membrane traffic protein#PC00150 CIOIN|Ensembl=ENSCING00000013983.2|UniProtKB=F6QAE6 F6QAE6 LOC100182930 PTHR28620:SF1 CENTROMERE PROTEIN V CENP-V_GFA DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000003665.3|UniProtKB=F7AD97 F7AD97 LOC100176467 PTHR14190:SF7 SUPPRESSOR OF ACTIN MUTATIONS 2/VACUOLAR PROTEIN SORTING 52 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 52 HOMOLOG syntaxin binding#GO:0019905;protein binding#GO:0005515;binding#GO:0005488;SNARE binding#GO:0000149 endosomal transport#GO:0016197;localization within membrane#GO:0051668;cellular localization#GO:0051641;vesicle-mediated transport to the plasma membrane#GO:0098876;vacuolar transport#GO:0007034;post-Golgi vesicle-mediated transport#GO:0006892;transport#GO:0006810;vesicle-mediated transport#GO:0016192;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987;cytosolic transport#GO:0016482;retrograde transport, endosome to Golgi#GO:0042147;localization#GO:0051179;endocytic recycling#GO:0032456;establishment of localization#GO:0051234;Golgi to vacuole transport#GO:0006896;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular vesicle#GO:0097708;vesicle tethering complex#GO:0099023;Golgi apparatus#GO:0005794;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150 CIOIN|Ensembl=ENSCING00000004369.3|UniProtKB=F7BDX5 F7BDX5 PTHR11571:SF224 GLUTATHIONE S-TRANSFERASE HEMATOPOIETIC PROSTAGLANDIN D SYNTHASE glutathione transferase activity#GO:0004364;transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824 sulfur compound metabolic process#GO:0006790;nitrogen compound metabolic process#GO:0006807;peptide metabolic process#GO:0006518;cellular modified amino acid metabolic process#GO:0006575;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular process#GO:0009987;glutathione metabolic process#GO:0006749;amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000001684.3|UniProtKB=F6X892 F6X892 LOC100176626 PTHR46212:SF3 PEFLIN GH27120P CIOIN|Ensembl=ENSCING00000018539.1|UniProtKB=H2XQJ8 H2XQJ8 LOC100178035 PTHR12645:SF0 ALR/ERV FAD-LINKED SULFHYDRYL OXIDASE ALR nucleotide binding#GO:0000166;protein-disulfide reductase activity#GO:0015035;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;flavin adenine dinucleotide binding#GO:0050660;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;disulfide oxidoreductase activity#GO:0015036;ion binding#GO:0043167;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 oxidase#PC00175;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000015708.2|UniProtKB=F6ZD42 F6ZD42 PTHR16146:SF46 INTELECTIN INTELECTIN-1A-RELATED CIOIN|Ensembl=ENSCING00000010799.3|UniProtKB=F6XKH4 F6XKH4 PTHR14499:SF136 POTASSIUM CHANNEL TETRAMERIZATION DOMAIN-CONTAINING GH08630P scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000014873.2|UniProtKB=F6ZAF3 F6ZAF3 PTHR14002:SF59 ENDOGLIN/TGF-BETA RECEPTOR TYPE III CUB AND ZONA PELLUCIDA-LIKE DOMAIN-CONTAINING PROTEIN 1-RELATED transmembrane signal receptor#PC00197 CIOIN|Ensembl=ENSCING00000005710.3|UniProtKB=F6U2S1 F6U2S1 PTHR11733:SF167 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI17812P1-RELATED hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;protein processing#GO:0016485;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 Endothelin signaling pathway#P00019>ECE1-3#P00585 CIOIN|Ensembl=ENSCING00000016200.2|UniProtKB=F6ZS91 F6ZS91 LOC100181886 PTHR15460:SF3 PEROXISOMAL MEMBRANE PROTEIN 4 PEROXISOMAL MEMBRANE PROTEIN 4 peroxisomal membrane#GO:0005778;cytoplasm#GO:0005737;bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;peroxisome#GO:0005777;microbody#GO:0042579;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000019376.1|UniProtKB=H2XY13 H2XY13 PTHR13060:SF0 SGT1 PROTEIN HSGT1 SUPPRESSOR OF GCR2 PROTEIN ECDYSONELESS HOMOLOG membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000008105.3|UniProtKB=F6YN50 F6YN50 nf-il2 PTHR15284:SF0 NUCLEAR FACTOR INTERLEUKIN-3-REGULATED PROTEIN GH23983P circadian rhythm#GO:0007623;rhythmic process#GO:0048511;regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;basic leucine zipper transcription factor#PC00056 CIOIN|Ensembl=ENSCING00000014026.2|UniProtKB=F6QVB5 F6QVB5 PTHR31703:SF2 UPF0669 PROTEIN C6ORF120 UPF0669 PROTEIN C6ORF120 CIOIN|Ensembl=ENSCING00000003826.2|UniProtKB=F6ZST9 F6ZST9 LOC100176983 PTHR11360:SF284 MONOCARBOXYLATE TRANSPORTER EG:103B4.3 PROTEIN-RELATED transporter#PC00227 CIOIN|Ensembl=ENSCING00000008841.3|UniProtKB=F7B059 F7B059 PTHR13806:SF46 FLOTILLIN-RELATED FLOTILLIN-1-RELATED enzyme binding#GO:0019899;protein binding#GO:0005515;protease binding#GO:0002020;binding#GO:0005488 localization#GO:0051179;protein localization to plasma membrane#GO:0072659;protein localization to cell periphery#GO:1990778;localization within membrane#GO:0051668;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;protein localization to membrane#GO:0072657;cellular process#GO:0009987;protein localization#GO:0008104 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 CIOIN|Ensembl=ENSCING00000018744.1|UniProtKB=H2XXU0 H2XXU0 PTHR45783:SF3 KINESIN LIGHT CHAIN KINESIN LIGHT CHAIN kinesin binding#GO:0019894;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;binding#GO:0005488 microtubule-based movement#GO:0007018;cellular process#GO:0009987;microtubule-based process#GO:0007017 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 Alzheimer disease-amyloid secretase pathway#P00003>kinesin#P00107 CIOIN|Ensembl=ENSCING00000022125.1|UniProtKB=H2Y2X7 H2Y2X7 LOC100177874 PTHR21625:SF0 NYD-SP28 PROTEIN DYNEIN REGULATORY COMPLEX SUBUNIT 2 regulation of microtubule-based process#GO:0032886;cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cell projection organization#GO:0030030;microtubule cytoskeleton organization#GO:0000226;cilium or flagellum-dependent cell motility#GO:0001539;protein-containing complex assembly#GO:0065003;cell motility#GO:0048870;cellular component organization#GO:0016043;axoneme assembly#GO:0035082;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031;regulation of biological process#GO:0050789;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cilium-dependent cell motility#GO:0060285;microtubule-based process#GO:0007017;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;regulation of cellular process#GO:0050794;microtubule bundle formation#GO:0001578;axonemal dynein complex assembly#GO:0070286;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;plasma membrane bounded cell projection assembly#GO:0120031 axoneme#GO:0005930;cytoplasmic region#GO:0099568;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;plasma membrane bounded cell projection cytoplasm#GO:0032838;membrane-bounded organelle#GO:0043227;ciliary plasm#GO:0097014;cytoskeleton#GO:0005856;cell projection#GO:0042995;cilium#GO:0005929 CIOIN|Ensembl=ENSCING00000004294.3|UniProtKB=F6TTF4 F6TTF4 LOC100187071 PTHR10177:SF593 CYCLINS G2_MITOTIC-SPECIFIC CYCLIN-A protein kinase regulator activity#GO:0019887;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207 regulation of protein kinase activity#GO:0045859;regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;mitotic cell cycle phase transition#GO:0044772;regulation of nitrogen compound metabolic process#GO:0051171;cell cycle process#GO:0022402;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;cell cycle phase transition#GO:0044770;mitotic cell cycle process#GO:1903047;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;regulation of primary metabolic process#GO:0080090;mitotic cell cycle#GO:0000278;regulation of macromolecule metabolic process#GO:0060255;regulation of molecular function#GO:0065009;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;regulation of protein serine/threonine kinase activity#GO:0071900;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cyclin-dependent protein serine/threonine kinase activity#GO:0000079;regulation of kinase activity#GO:0043549;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;protein kinase complex#GO:1902911;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622 kinase activator#PC00138 CIOIN|Ensembl=ENSCING00000020660.1|UniProtKB=H2XR99 H2XR99 PTHR13233:SF0 MICROSPHERULE PROTEIN 1 MICROSPHERULE PROTEIN 1 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of RNA metabolic process#GO:0051254;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 histone acetyltransferase complex#GO:0000123;acetyltransferase complex#GO:1902493;chromatin#GO:0000785;protein-DNA complex#GO:0032993;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein acetyltransferase complex#GO:0031248;protein-containing complex#GO:0032991;chromosome#GO:0005694 CIOIN|Ensembl=ENSCING00000021500.1|UniProtKB=H2XYR7 H2XYR7 LOC100186321 PTHR12383:SF16 PROTEASE FAMILY S26 MITOCHONDRIAL INNER MEMBRANE PROTEASE-RELATED MITOCHONDRIAL INNER MEMBRANE PROTEASE SUBUNIT 1 protease#PC00190;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000018333.1|UniProtKB=H2Y0U8 H2Y0U8 PTHR21676:SF6 PROTEIN STUM PROTEIN STUM CIOIN|Ensembl=ENSCING00000012882.2|UniProtKB=F6PUA0 F6PUA0 LOC100184472 PTHR10671:SF34 EPITHELIAL MEMBRANE PROTEIN-RELATED PROTEIN NKG7 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cytoskeletal protein#PC00085 CIOIN|Ensembl=ENSCING00000022491.1|UniProtKB=H2XTL6 H2XTL6 LOC100177611 PTHR45701:SF9 SYNAPTOBREVIN FAMILY MEMBER V-SNARE COILED-COIL HOMOLOGY DOMAIN-CONTAINING PROTEIN syntaxin binding#GO:0019905;molecular adaptor activity#GO:0060090;protein binding#GO:0005515;SNAP receptor activity#GO:0005484;binding#GO:0005488;SNARE binding#GO:0000149;protein-macromolecule adaptor activity#GO:0030674 localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;vesicle fusion#GO:0006906;membrane fusion#GO:0061025;establishment of localization#GO:0051234;membrane organization#GO:0061024;organelle organization#GO:0006996;organelle membrane fusion#GO:0090174;transport#GO:0006810;vesicle-mediated transport#GO:0016192;vesicle organization#GO:0016050;cellular component organization#GO:0016043;cellular process#GO:0009987;organelle fusion#GO:0048284 cytoplasm#GO:0005737;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;SNARE complex#GO:0031201;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150 Opioid proenkephalin pathway#P05915>SNARE Complex#P05986;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>SNARE Complex#P01066;Thyrotropin-releasing hormone receptor signaling pathway#P04394>SNARE Complex#P04582;Dopamine receptor mediated signaling pathway#P05912>SNARE Complex#P05956;Adrenaline and noradrenaline biosynthesis#P00001>SNARE#P00072;Beta3 adrenergic receptor signaling pathway#P04379>SNARE Complex#P04447;5HT4 type receptor mediated signaling pathway#P04376>SNARE Complex#P04428;Opioid prodynorphin pathway#P05916>SNARE Complex#P05996;Alpha adrenergic receptor signaling pathway#P00002>SNARE#P00074;Nicotinic acetylcholine receptor signaling pathway#P00044>SNARE Complex#P01091;5HT3 type receptor mediated signaling pathway#P04375>SNARE Complex#P04423;Ionotropic glutamate receptor pathway#P00037>SNARE Complex#P01013;Metabotropic glutamate receptor group II pathway#P00040>SNARE Complex#P01049;Opioid proopiomelanocortin pathway#P05917>SNARE Complex#P06005;Beta1 adrenergic receptor signaling pathway#P04377>SNARE Complex#P04435;Cortocotropin releasing factor receptor signaling pathway#P04380>SNARE Complex#P04457;Metabotropic glutamate receptor group III pathway#P00039>SNARE Complex#P01042;Oxytocin receptor mediated signaling pathway#P04391>SNARE Complex#P04532;5HT2 type receptor mediated signaling pathway#P04374>SNARE Complex#P04415;5HT1 type receptor mediated signaling pathway#P04373>SNARE Complex#P04405;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>SNARE Complex#P01079;Beta2 adrenergic receptor signaling pathway#P04378>SNARE Complex#P04442 CIOIN|Ensembl=ENSCING00000010113.2|UniProtKB=F6PII0 F6PII0 LOC100185470 PTHR13610:SF9 METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN FI06469P N-methyltransferase activity#GO:0008170;transferase activity#GO:0016740;catalytic activity#GO:0003824;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;protein-lysine N-methyltransferase activity#GO:0016279;catalytic activity, acting on a protein#GO:0140096;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;protein methyltransferase activity#GO:0008276;lysine N-methyltransferase activity#GO:0016278 regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of molecular function#GO:0044093;protein modification process#GO:0036211;positive regulation of cation channel activity#GO:2001259;regulation of localization#GO:0032879;peptidyl-amino acid modification#GO:0018193;regulation of monoatomic cation transmembrane transport#GO:1904062;regulation of catalytic activity#GO:0050790;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;regulation of transport#GO:0051049;regulation of molecular function#GO:0065009;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;regulation of monoatomic ion transmembrane transporter activity#GO:0032412;regulation of transmembrane transporter activity#GO:0022898;regulation of monoatomic ion transport#GO:0043269;protein metabolic process#GO:0019538;regulation of transporter activity#GO:0032409;positive regulation of biological process#GO:0048518;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;regulation of monoatomic ion transmembrane transport#GO:0034765;regulation of transmembrane transport#GO:0034762;macromolecule metabolic process#GO:0043170;positive regulation of catalytic activity#GO:0043085;organonitrogen compound metabolic process#GO:1901564;positive regulation of transport#GO:0051050;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;macromolecule methylation#GO:0043414;regulation of cellular biosynthetic process#GO:0031326;methylation#GO:0032259;positive regulation of transporter activity#GO:0032411;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000007499.3|UniProtKB=F6XVX1 F6XVX1 PTHR22957:SF653 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN FI17814P1 nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 regulation of molecular function#GO:0065009;regulation of GTPase activity#GO:0043087;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;activation of GTPase activity#GO:0090630;biological regulation#GO:0065007;positive regulation of molecular function#GO:0044093;regulation of hydrolase activity#GO:0051336;regulation of catalytic activity#GO:0050790;positive regulation of hydrolase activity#GO:0051345 GTPase-activating protein#PC00257 CIOIN|Ensembl=ENSCING00000022703.1|UniProtKB=H2XZE3 H2XZE3 PTHR11039:SF64 NEBULIN NEBULIN-RELATED-ANCHORING PROTEIN-LIKE cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;actin binding#GO:0003779;actin filament binding#GO:0051015 CIOIN|Ensembl=ENSCING00000005770.3|UniProtKB=F6RMF5 F6RMF5 LOC100183015 PTHR24418:SF373 TYROSINE-PROTEIN KINASE TYROSINE-PROTEIN KINASE SRC42A protein tyrosine kinase activity#GO:0004713;non-membrane spanning protein tyrosine kinase activity#GO:0004715;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein binding#GO:0005515;catalytic activity, acting on a protein#GO:0140096;signaling receptor binding#GO:0005102;kinase activity#GO:0016301;protein kinase activity#GO:0004672 response to external biotic stimulus#GO:0043207;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;immune response#GO:0006955;developmental process#GO:0032502;cell communication#GO:0007154;cellular process#GO:0009987;defense response to symbiont#GO:0140546;regulation of biological process#GO:0050789;immune system process#GO:0002376;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;cell differentiation#GO:0030154;enzyme-linked receptor protein signaling pathway#GO:0007167;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological process involved in interspecies interaction between organisms#GO:0044419;biological regulation#GO:0065007;innate immune response#GO:0045087;defense response#GO:0006952;signaling#GO:0023052;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169 non-receptor tyrosine protein kinase#PC00168 Parkinson disease#P00049>Src kinase#P01230;Integrin signalling pathway#P00034>Src#P00940 CIOIN|Ensembl=ENSCING00000002712.4|UniProtKB=F6UDU8 F6UDU8 LOC100181294 PTHR44117:SF1 INTRAFLAGELLAR TRANSPORT PROTEIN 88 HOMOLOG INTRAFLAGELLAR TRANSPORT PROTEIN 88 HOMOLOG kinesin binding#GO:0019894;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;binding#GO:0005488 non-motile cilium assembly#GO:1905515;cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;cilium assembly#GO:0060271;cell projection organization#GO:0030030;transport#GO:0006810;microtubule-based movement#GO:0007018;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;transport along microtubule#GO:0010970;cell projection assembly#GO:0030031;intraciliary transport#GO:0042073;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based transport#GO:0099111;microtubule-based process#GO:0007017;establishment of localization#GO:0051234;organelle organization#GO:0006996;cytoskeleton-dependent intracellular transport#GO:0030705;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;protein-containing complex localization#GO:0031503 microtubule organizing center#GO:0005815;non-motile cilium#GO:0097730;ciliary base#GO:0097546;cellular anatomical entity#GO:0110165;centriole#GO:0005814;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;ciliary basal body#GO:0036064;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;cell projection#GO:0042995;cilium#GO:0005929 CIOIN|Ensembl=ENSCING00000014024.2|UniProtKB=F6QH89 F6QH89 PTHR15622:SF2 WD40 REPEAT PROTEIN U4_U6 SMALL NUCLEAR RIBONUCLEOPROTEIN PRP4 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein polyubiquitination#GO:0000209;post-translational protein modification#GO:0043687;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;organic substance metabolic process#GO:0071704;primary metabolic process#GO:0044238;metabolic process#GO:0008152 CIOIN|Ensembl=ENSCING00000008570.3|UniProtKB=F6X0K4 F6X0K4 LOC100175385 PTHR10036:SF3 CD59 GLYCOPROTEIN PROTEIN SLEEPLESS-RELATED CIOIN|Ensembl=ENSCING00000003322.3|UniProtKB=H2XQD7 H2XQD7 LOC104266248 PTHR13082:SF0 SAP18 HISTONE DEACETYLASE COMPLEX SUBUNIT SAP18 molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;protein binding#GO:0005515;transcription factor binding#GO:0008134 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of biosynthetic process#GO:0009890;negative regulation of RNA metabolic process#GO:0051253;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of metabolic process#GO:0009892;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 Hedgehog signaling pathway#P00025>Sap18#P00697 CIOIN|Ensembl=ENSCING00000002010.2|UniProtKB=F6WSV9 F6WSV9 PTHR11409:SF43 ADENOSINE DEAMINASE ADENOSINE DEAMINASE hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;adenosine deaminase activity#GO:0004000;deaminase activity#GO:0019239;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;nucleoside metabolic process#GO:0009116;glycosyl compound catabolic process#GO:1901658;carbohydrate derivative metabolic process#GO:1901135;heterocycle catabolic process#GO:0046700;organonitrogen compound catabolic process#GO:1901565;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase metabolic process#GO:0009112;nucleobase-containing compound metabolic process#GO:0006139;cellular nitrogen compound catabolic process#GO:0044270;purine-containing compound catabolic process#GO:0072523;organic cyclic compound metabolic process#GO:1901360;purine nucleoside metabolic process#GO:0042278;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;purine-containing compound metabolic process#GO:0072521;catabolic process#GO:0009056;nucleoside catabolic process#GO:0009164;organic substance catabolic process#GO:1901575;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;carbohydrate derivative catabolic process#GO:1901136;purine nucleobase metabolic process#GO:0006144;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;purine nucleoside catabolic process#GO:0006152;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;aromatic compound catabolic process#GO:0019439;nucleobase-containing compound biosynthetic process#GO:0034654;small molecule catabolic process#GO:0044282;nucleobase-containing small molecule catabolic process#GO:0034656;adenosine metabolic process#GO:0046085;organic cyclic compound catabolic process#GO:1901361;aromatic compound biosynthetic process#GO:0019438;small molecule biosynthetic process#GO:0044283;nucleobase-containing compound catabolic process#GO:0034655;glycosyl compound metabolic process#GO:1901657;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 deaminase#PC00088;metabolite interconversion enzyme#PC00262;hydrolase#PC00121 Adenine and hypoxanthine salvage pathway#P02723>Adenosine deaminase#P02811;Adenine and hypoxanthine salvage pathway#P02723>Deoxyadenosine deaminase#P02807 CIOIN|Ensembl=ENSCING00000022992.1|UniProtKB=H2XXW8 H2XXW8 PTHR23341:SF2 HIGH MOBILITY GROUP PROTEINS HMG-A AND C HIGH MOBILITY GROUP PROTEIN HMG-12 molecular adaptor activity#GO:0060090;transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;protein-macromolecule adaptor activity#GO:0030674 regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 HMG box transcription factor#PC00024 CIOIN|Ensembl=ENSCING00000013107.2|UniProtKB=F7BNX3 F7BNX3 PTHR10075:SF100 BASIGIN RELATED FASCICLIN-2 cell adhesion molecule binding#GO:0050839;cell-cell adhesion mediator activity#GO:0098632;protein binding#GO:0005515;binding#GO:0005488 neuron projection guidance#GO:0097485;cell recognition#GO:0008037;neurogenesis#GO:0022008;cell projection organization#GO:0030030;developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cellular anatomical entity morphogenesis#GO:0032989;system development#GO:0048731;cell differentiation#GO:0030154;axon guidance#GO:0007411;anatomical structure morphogenesis#GO:0009653;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;axonogenesis#GO:0007409;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;homophilic cell adhesion via plasma membrane adhesion molecules#GO:0007156;cell-cell adhesion via plasma-membrane adhesion molecules#GO:0098742;cell-cell adhesion#GO:0098609;cellular component organization#GO:0016043;cell adhesion#GO:0007155;cell morphogenesis#GO:0000902;cellular process#GO:0009987;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;cell morphogenesis involved in neuron differentiation#GO:0048667;anatomical structure development#GO:0048856;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699 neuron projection#GO:0043005;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886;axon#GO:0030424 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000007502.3|UniProtKB=F6X7U3 F6X7U3 PTHR32059:SF0 RAB11-BINDING PROTEIN RELCH RAB11-BINDING PROTEIN RELCH trans-Golgi network#GO:0005802;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;organelle subcompartment#GO:0031984;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;recycling endosome#GO:0055037;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791 CIOIN|Ensembl=ENSCING00000005713.3|UniProtKB=F6WPJ4 F6WPJ4 PTHR24409:SF295 ZINC FINGER PROTEIN 142 AZ2-RELATED sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 CIOIN|Ensembl=ENSCING00000004263.3|UniProtKB=F6V6N1 F6V6N1 PTHR10877:SF183 POLYCYSTIN FAMILY MEMBER AT14535P-RELATED ion channel#PC00133;transporter#PC00227 CIOIN|Ensembl=ENSCING00000018311.1|UniProtKB=H2XN47 H2XN47 LOC100182614 PTHR11040:SF211 ZINC/IRON TRANSPORTER ZINC TRANSPORTER ZIP11 inorganic molecular entity transmembrane transporter activity#GO:0015318;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;inorganic cation transmembrane transporter activity#GO:0022890;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075 localization#GO:0051179;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;monoatomic cation transport#GO:0006812;transition metal ion transport#GO:0000041;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655 cellular anatomical entity#GO:0110165;membrane#GO:0016020 secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000020811.1|UniProtKB=H2XU70 H2XU70 LOC100177017 PTHR13381:SF0 RNA POLYMERASE II HOLOENZYME COMPONENT SRB7 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 21 molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;protein-macromolecule adaptor activity#GO:0030674 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;mediator complex#GO:0016592;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031;DNA-directed RNA polymerase#PC00019 CIOIN|Ensembl=ENSCING00000022842.1|UniProtKB=H2XYF3 H2XYF3 PTHR11533:SF301 PROTEASE M1 ZINC METALLOPROTEASE AMINOPEPTIDASE metalloexopeptidase activity#GO:0008235;metallopeptidase activity#GO:0008237;small molecule binding#GO:0036094;zinc ion binding#GO:0008270;binding#GO:0005488;catalytic activity#GO:0003824;transition metal ion binding#GO:0046914;amide binding#GO:0033218;metal ion binding#GO:0046872;peptidase activity#GO:0008233;metalloaminopeptidase activity#GO:0070006;cation binding#GO:0043169;peptide binding#GO:0042277;hydrolase activity#GO:0016787;aminopeptidase activity#GO:0004177;exopeptidase activity#GO:0008238;ion binding#GO:0043167;catalytic activity, acting on a protein#GO:0140096 macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;peptide catabolic process#GO:0043171;cellular process#GO:0009987;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;membrane#GO:0016020;extracellular region#GO:0005576;intracellular anatomical structure#GO:0005622 metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000012347.2|UniProtKB=F6ZTE1 F6ZTE1 LOC100175499 PTHR19878:SF8 AUTOPHAGY PROTEIN 16-LIKE AUTOPHAGY-RELATED 16, ISOFORM F CIOIN|Ensembl=ENSCING00000018658.1|UniProtKB=H2XRG5 H2XRG5 PTHR19143:SF458 FIBRINOGEN/TENASCIN/ANGIOPOEITIN FIBRINOGEN C-TERMINAL DOMAIN-CONTAINING PROTEIN-RELATED external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 CIOIN|Ensembl=ENSCING00000003530.3|UniProtKB=F6YB82 F6YB82 PTHR23147:SF189 SERINE/ARGININE RICH SPLICING FACTOR SERINE AND ARGININE-RICH-SPLICING FACTOR 3A nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;nuclear speck#GO:0016607;organelle#GO:0043226;nuclear body#GO:0016604;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA splicing factor#PC00148;RNA processing factor#PC00147;RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000001081.3|UniProtKB=F7B0F3 F7B0F3 PTHR13087:SF0 NF-KAPPA B ACTIVATING PROTEIN NFKB ACTIVATING PROTEIN LIKE regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of biosynthetic process#GO:0009889;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000021369.1|UniProtKB=H2Y234 H2Y234 LOC100183461 PTHR11954:SF6 D-DOPACHROME DECARBOXYLASE MACROPHAGE MIGRATION INHIBITORY FACTOR isomerase activity#GO:0016853;catalytic activity#GO:0003824 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 decarboxylase#PC00089;lyase#PC00144 CIOIN|Ensembl=ENSCING00000020404.1|UniProtKB=H2XUH7 H2XUH7 PTHR14140:SF45 E3 UBIQUITIN-PROTEIN LIGASE UHRF-RELATED RING-TYPE E3 UBIQUITIN TRANSFERASE transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 negative regulation of gene expression#GO:0010629;negative regulation of cellular metabolic process#GO:0031324;protein-DNA complex organization#GO:0071824;negative regulation of biological process#GO:0048519;macromolecule modification#GO:0043412;protein modification process#GO:0036211;post-translational protein modification#GO:0043687;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;negative regulation of biosynthetic process#GO:0009890;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular component organization#GO:0016043;negative regulation of metabolic process#GO:0009892;negative regulation of gene expression, epigenetic#GO:0045814;cellular process#GO:0009987;primary metabolic process#GO:0044238;epigenetic regulation of gene expression#GO:0040029;cellular component organization or biogenesis#GO:0071840;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;protein-containing complex organization#GO:0043933;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;chromatin organization#GO:0006325;chromatin remodeling#GO:0006338;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000000706.3|UniProtKB=F6QLG8 F6QLG8 PTHR12905:SF0 METALLOPHOSPHOESTERASE CALCINEURIN-LIKE PHOSPHOESTERASE DOMAIN-CONTAINING PROTEIN esterase#PC00097 CIOIN|Ensembl=ENSCING00000013322.2|UniProtKB=Q1RLI9 Q1RLI9 Ci-ZF(Bbox_RING)-1 PTHR25462:SF229 BONUS, ISOFORM C-RELATED TRANSCRIPTION INTERMEDIARY FACTOR 1-BETA transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;protein monoubiquitination#GO:0006513;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000005291.3|UniProtKB=F7B5P4 F7B5P4 PTHR22767:SF2 N-TERMINAL ACETYLTRANSFERASE-RELATED N(ALPHA)-ACETYLTRANSFERASE 15_16, ISOFORM A macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;peptidyl-amino acid modification#GO:0018193;protein acylation#GO:0043543;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;protein acetylation#GO:0006473;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 acetyltransferase#PC00038 CIOIN|Ensembl=ENSCING00000003006.3|UniProtKB=F6QFA2 F6QFA2 LOC100183243 PTHR12112:SF39 BNIP - RELATED EG:152A3.5 PROTEIN (FBGN0003116_PN PROTEIN) hydrolase activity#GO:0016787;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;exopolyphosphatase activity#GO:0004309;catalytic activity#GO:0003824 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 phosphodiesterase#PC00185;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000009216.3|UniProtKB=F6WMW7 F6WMW7 PTHR11929:SF145 ALPHA- 1,3 -FUCOSYLTRANSFERASE ALPHA-(1,3)-FUCOSYLTRANSFERASE FUT-1 transferase activity#GO:0016740;fucosyltransferase activity#GO:0008417;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 glycosylation#GO:0070085;metabolic process#GO:0008152 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000001932.3|UniProtKB=F6ZIC6 F6ZIC6 LOC100181334 PTHR24068:SF129 UBIQUITIN-CONJUGATING ENZYME E2 NEDD8-CONJUGATING ENZYME UBE2F ubiquitin-like protein conjugating enzyme activity#GO:0061650;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin conjugating enzyme activity#GO:0061631;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein neddylation#GO:0045116;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein polyubiquitination#GO:0000209;post-translational protein modification#GO:0043687;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000017174.2|UniProtKB=F6T4C7 F6T4C7 LOC664634 PTHR34930:SF2 GEO05313P1 MICROTUBULE-ASSOCIATED PROTEIN JUPITER cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 CIOIN|Ensembl=ENSCING00000006308.3|UniProtKB=F6SGF7 F6SGF7 PTHR48493:SF1 UBIQUITIN-LIKE DOMAIN-CONTAINING CTD PHOSPHATASE 1 UBIQUITIN-LIKE DOMAIN-CONTAINING CTD PHOSPHATASE 1 CIOIN|Ensembl=ENSCING00000022303.1|UniProtKB=H2Y2K3 H2Y2K3 LOC100169894 PTHR24302:SF15 CYTOCHROME P450 FAMILY 3 FATTY-ACID PEROXYGENASE oxygenase#PC00177;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000022248.1|UniProtKB=H2Y054 H2Y054 LOC100186168 PTHR47978:SF21 FAMILY NOT NAMED RAS-RELATED PROTEIN RAB-26 GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;anion binding#GO:0043168;ion binding#GO:0043167 regulation of biological process#GO:0050789;regulation of transport#GO:0051049;regulation of secretion#GO:0051046;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of localization#GO:0032879;regulation of secretion by cell#GO:1903530;regulation of vesicle-mediated transport#GO:0060627;regulation of exocytosis#GO:0017157 cytoplasm#GO:0005737;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 small GTPase#PC00208;G-protein#PC00020 CIOIN|Ensembl=ENSCING00000017528.2|UniProtKB=F6SET0 F6SET0 PTHR31159:SF1 COMM DOMAIN-CONTAINING PROTEIN 3 COMM DOMAIN-CONTAINING PROTEIN 3 CIOIN|Ensembl=ENSCING00000012019.2|UniProtKB=F6SUL1 F6SUL1 LOC100181877 PTHR24347:SF427 SERINE/THREONINE-PROTEIN KINASE SERINE_THREONINE-PROTEIN KINASE DCLK3 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000002956.3|UniProtKB=A0A1W3JD12 A0A1W3JD12 LOC100180448 PTHR23058:SF0 PEROXISOMAL MEMBRANE PROTEIN PEX14 PEROXISOMAL MEMBRANE PROTEIN PEX14 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 cellular localization#GO:0051641;intracellular protein transmembrane transport#GO:0065002;transmembrane transport#GO:0055085;macromolecule localization#GO:0033036;protein import into peroxisome matrix#GO:0016558;transport#GO:0006810;protein transmembrane transport#GO:0071806;nitrogen compound transport#GO:0071705;establishment of protein localization to organelle#GO:0072594;cellular component organization#GO:0016043;cellular process#GO:0009987;protein transmembrane import into intracellular organelle#GO:0044743;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;organelle organization#GO:0006996;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;protein localization to organelle#GO:0033365;peroxisome organization#GO:0007031 bounding membrane of organelle#GO:0098588;peroxisomal membrane#GO:0005778;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;transporter complex#GO:1990351;peroxisome#GO:0005777;membrane-bounded organelle#GO:0043227;microbody#GO:0042579;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 primary active transporter#PC00068;transporter#PC00227 CIOIN|Ensembl=ENSCING00000001284.2|UniProtKB=F6ZCN2 F6ZCN2 PTHR11360:SF318 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER 12 localization#GO:0051179;organic substance transport#GO:0071702;monocarboxylic acid transport#GO:0015718;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;organic anion transport#GO:0015711;organic acid transport#GO:0015849;transport#GO:0006810;nitrogen compound transport#GO:0071705;organic acid transmembrane transport#GO:1903825;carboxylic acid transport#GO:0046942;cellular process#GO:0009987;carboxylic acid transmembrane transport#GO:1905039 transporter#PC00227 CIOIN|Ensembl=ENSCING00000014061.2|UniProtKB=F6PUF3 F6PUF3 PTHR11733:SF133 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED PHOSPHATE-REGULATING NEUTRAL ENDOPEPTIDASE PHEX hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;protein processing#GO:0016485;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 Endothelin signaling pathway#P00019>ECE1-3#P00585 CIOIN|Ensembl=ENSCING00000015381.2|UniProtKB=F6XXK1 F6XXK1 LOC100178344 PTHR13080:SF20 ATP SYNTHASE F CHAIN, MITOCHONDRIAL-RELATED ATP SYNTHASE SUBUNIT F, MITOCHONDRIAL-RELATED monoatomic cation channel activity#GO:0005261;ligase activity#GO:0016874;inorganic molecular entity transmembrane transporter activity#GO:0015318;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;catalytic activity#GO:0003824;proton transmembrane transporter activity#GO:0015078;proton channel activity#GO:0015252;proton-transporting ATP synthase activity, rotational mechanism#GO:0046933;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;inorganic cation transmembrane transporter activity#GO:0022890;channel activity#GO:0015267;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 cellular aromatic compound metabolic process#GO:0006725;ribonucleoside triphosphate metabolic process#GO:0009199;nucleoside triphosphate metabolic process#GO:0009141;carbohydrate derivative metabolic process#GO:1901135;ATP biosynthetic process#GO:0006754;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;energy derivation by oxidation of organic compounds#GO:0015980;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ATP metabolic process#GO:0046034;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;purine nucleoside triphosphate biosynthetic process#GO:0009145;aerobic respiration#GO:0009060;cellular respiration#GO:0045333;heterocycle metabolic process#GO:0046483;purine ribonucleoside triphosphate metabolic process#GO:0009205;generation of precursor metabolites and energy#GO:0006091;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;ribonucleoside triphosphate biosynthetic process#GO:0009201;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;proton motive force-driven ATP synthesis#GO:0015986;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;oxidative phosphorylation#GO:0006119;aromatic compound biosynthetic process#GO:0019438;nucleoside triphosphate biosynthetic process#GO:0009142;organophosphate metabolic process#GO:0019637;purine nucleoside triphosphate metabolic process#GO:0009144;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;ATPase complex#GO:1904949;organelle inner membrane#GO:0019866;mitochondrial proton-transporting ATP synthase complex#GO:0005753;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;proton-transporting two-sector ATPase complex#GO:0016469;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial envelope#GO:0005740;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227;proton-transporting ATP synthase complex#GO:0045259;mitochondrial protein-containing complex#GO:0098798 ATP synthase#PC00002;primary active transporter#PC00068;transporter#PC00227 CIOIN|Ensembl=ENSCING00000002692.3|UniProtKB=F6X159 F6X159 mapkk3_6 PTHR48013:SF11 DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 5-RELATED LICORNE transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;MAPK cascade#GO:0000165;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;cellular process#GO:0009987;signaling#GO:0023052 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 FGF signaling pathway#P00021>MKK3,6#P00625;EGF receptor signaling pathway#P00018>MKK3,6#P00540;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>MEK#P00891 CIOIN|Ensembl=ENSCING00000022190.1|UniProtKB=H2XPD1 H2XPD1 LOC100177850 PTHR11276:SF42 DNA POLYMERASE TYPE-X FAMILY MEMBER DNA POLYMERASE BETA DNA-directed DNA polymerase activity#GO:0003887;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on DNA#GO:0140097;DNA polymerase activity#GO:0034061 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;base-excision repair#GO:0006284;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;double-strand break repair via nonhomologous end joining#GO:0006303;nucleic acid metabolic process#GO:0090304;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;response to stress#GO:0006950;nitrogen compound metabolic process#GO:0006807;cellular response to stress#GO:0033554;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-directed DNA polymerase#PC00018 CIOIN|Ensembl=ENSCING00000000977.3|UniProtKB=F7A8J9 F7A8J9 LOC100178230 PTHR10383:SF48 SERINE INCORPORATOR SERINE INCORPORATOR 1-LIKE cellular anatomical entity#GO:0110165;membrane#GO:0016020 protein-binding activity modulator#PC00095 CIOIN|Ensembl=ENSCING00000007288.3|UniProtKB=F6S7X2 F6S7X2 PTHR22298:SF29 ENDO-1,4-BETA-GLUCANASE ENDOGLUCANASE CIOIN|Ensembl=ENSCING00000002959.3|UniProtKB=F6R497 F6R497 PTHR14453:SF67 PARP/ZINC FINGER CCCH TYPE DOMAIN CONTAINING PROTEIN POLY [ADP-RIBOSE] POLYMERASE molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714;protein-macromolecule adaptor activity#GO:0030674 negative regulation of gene expression#GO:0010629;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of biosynthetic process#GO:0009890;negative regulation of metabolic process#GO:0009892;regulation of biological process#GO:0050789;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000017426.2|UniProtKB=F6PLM3 F6PLM3 PTHR45750:SF3 GH11602P HISTONE ACETYLTRANSFERASE histone modifying activity#GO:0140993;histone acetyltransferase activity#GO:0004402;transferase activity#GO:0016740;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;N-acetyltransferase activity#GO:0008080;acetyltransferase activity#GO:0016407;peptide-lysine-N-acetyltransferase activity#GO:0061733;peptide N-acetyltransferase activity#GO:0034212;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;N-acyltransferase activity#GO:0016410 positive regulation of nitrogen compound metabolic process#GO:0051173;protein-DNA complex organization#GO:0071824;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;regulation of DNA-templated transcription#GO:0006355;cellular component organization#GO:0016043;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA metabolic process#GO:0051252;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;protein-containing complex organization#GO:0043933;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;chromatin organization#GO:0006325;positive regulation of RNA metabolic process#GO:0051254;chromatin remodeling#GO:0006338;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 histone acetyltransferase complex#GO:0000123;acetyltransferase complex#GO:1902493;protein-DNA complex#GO:0032993;catalytic complex#GO:1902494;chromatin#GO:0000785;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein acetyltransferase complex#GO:0031248;protein-containing complex#GO:0032991;chromosome#GO:0005694 Notch signaling pathway#P00045>CoA#P01100 CIOIN|Ensembl=ENSCING00000022741.1|UniProtKB=H2XT41 H2XT41 LOC100178827 PTHR19317:SF0 PRENYLATED RAB ACCEPTOR 1-RELATED PRENYLATED RAB ACCEPTOR PROTEIN 1 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150 CIOIN|Ensembl=ENSCING00000018876.1|UniProtKB=H2XQ72 H2XQ72 LOC100178577 PTHR21502:SF4 ZINC FINGER PROTEIN DZIP1 RILP-LIKE PROTEIN HOMOLOG enzyme binding#GO:0019899;protein binding#GO:0005515;small GTPase binding#GO:0031267;binding#GO:0005488 organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cell projection organization#GO:0030030;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;microtubule cytoskeleton#GO:0015630;ciliary basal body#GO:0036064;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;cilium#GO:0005929;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 CIOIN|Ensembl=ENSCING00000016523.2|UniProtKB=H2XVL7 H2XVL7 PTHR11711:SF322 ADP RIBOSYLATION FACTOR-RELATED ADP-RIBOSYLATION FACTOR 6 carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167 cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 G-protein#PC00020 Integrin signalling pathway#P00034>Arf6#P00919;Huntington disease#P00029>ARF#P00786 CIOIN|Ensembl=ENSCING00000015003.2|UniProtKB=F6U7G3 F6U7G3 PTHR45789:SF2 FI18025P1 FI18025P1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000024475.1|UniProtKB=H2XJQ9 H2XJQ9 PTHR24261:SF7 PLASMINOGEN-RELATED KRINGLE DOMAIN-CONTAINING PROTEIN serine protease#PC00203;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000004772.3|UniProtKB=F6PM34 F6PM34 PTHR22881:SF27 BROMODOMAIN CONTAINING PROTEIN BROMODOMAIN CONTAINING 7_9 chromatin/chromatin-binding, or -regulatory protein#PC00077 CIOIN|Ensembl=ENSCING00000012917.2|UniProtKB=F6RMM4 F6RMM4 PTHR19143:SF394 FIBRINOGEN/TENASCIN/ANGIOPOEITIN ANGIOPOIETIN-RELATED PROTEIN 3-LIKE external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 CIOIN|Ensembl=ENSCING00000009490.3|UniProtKB=F6Y9J0 F6Y9J0 LOC100187240 PTHR36978:SF4 P-LOOP CONTAINING NUCLEOTIDE TRIPHOSPHATE HYDROLASE P-LOOP CONTAINING NUCLEOSIDE TRIPHOSPHATE HYDROLASE PROTEIN metabolite interconversion enzyme#PC00262;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000010643.3|UniProtKB=F6WT59 F6WT59 PTHR23023:SF226 DIMETHYLANILINE MONOOXYGENASE FLAVIN-CONTAINING MONOOXYGENASE oxygenase#PC00177;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000005069.3|UniProtKB=F6ZLS3 F6ZLS3 LOC100181611 PTHR10924:SF4 MAJOR FACILITATOR SUPERFAMILY PROTEIN-RELATED GH15861P tetrapyrrole binding#GO:0046906;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;binding#GO:0005488;organic cyclic compound binding#GO:0097159;heme binding#GO:0020037 localization#GO:0051179;organic substance transport#GO:0071702;metal ion transport#GO:0030001;establishment of localization#GO:0051234;transport#GO:0006810;monoatomic cation transport#GO:0006812;nitrogen compound transport#GO:0071705;iron ion transport#GO:0006826;transition metal ion transport#GO:0000041;monoatomic ion transport#GO:0006811 cellular anatomical entity#GO:0110165;membrane#GO:0016020 secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000002468.3|UniProtKB=F7B4M8 F7B4M8 LOC100175532 PTHR11705:SF153 PROTEASE FAMILY M14 CARBOXYPEPTIDASE A,B ZINC CARBOXYPEPTIDASE A 1-LIKE PROTEIN metalloexopeptidase activity#GO:0008235;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;metallocarboxypeptidase activity#GO:0004181;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;carboxypeptidase activity#GO:0004180 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 metalloprotease#PC00153;protease#PC00190 CIOIN|Ensembl=ENSCING00000001801.3|UniProtKB=F6X5Q9 F6X5Q9 LOC100181680 PTHR12497:SF0 TAZ PROTEIN TAFAZZIN TAFAZZIN acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;O-acyltransferase activity#GO:0008374 acyltransferase#PC00042;transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000004114.3|UniProtKB=F6XV81 F6XV81 LOC100176212 PTHR20948:SF2 TRANSMEMBRANE PROTEIN 164 TRANSMEMBRANE PROTEIN 164 CIOIN|Ensembl=ENSCING00000000157.3|UniProtKB=F6ZH80 F6ZH80 PTHR10334:SF591 CYSTEINE-RICH SECRETORY PROTEIN-RELATED GLIOMA PATHOGENESIS-RELATED PROTEIN 1-LIKE extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 defense/immunity protein#PC00090 CIOIN|Ensembl=ENSCING00000016625.2|UniProtKB=F6RKQ2 F6RKQ2 PTHR43995:SF1 PRE-MRNA-PROCESSING FACTOR 19 PRE-MRNA-PROCESSING FACTOR 19 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;mRNA splicing, via spliceosome#GO:0000398;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;U2-type spliceosomal complex#GO:0005684;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;Prp19 complex#GO:0000974;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622 RNA processing factor#PC00147;RNA metabolism protein#PC00031 mRNA splicing#P00058>U4#P01476 CIOIN|Ensembl=ENSCING00000018014.1|UniProtKB=H2XUZ9 H2XUZ9 LOC100186201 PTHR31807:SF37 AUGMIN FAMILY MEMBER HAUS AUGMIN-LIKE COMPLEX SUBUNIT 8 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;cellular component organization#GO:0016043;cellular process#GO:0009987;chromosome segregation#GO:0007059;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;spindle assembly#GO:0051225;cytoskeleton organization#GO:0007010;cell cycle#GO:0007049;spindle organization#GO:0007051;non-membrane-bounded organelle assembly#GO:0140694 supramolecular complex#GO:0099080;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;microtubule#GO:0005874 CIOIN|Ensembl=ENSCING00000011675.1|UniProtKB=F6X8I8 F6X8I8 PTHR23349:SF63 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, TWIST FER3-LIKE PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 basic helix-loop-helix transcription factor#PC00055 CIOIN|Ensembl=ENSCING00000013621.2|UniProtKB=F6V198 F6V198 PTHR42778:SF1 2-AMINOETHYLPHOSPHONATE--PYRUVATE TRANSAMINASE 2-AMINOETHYLPHOSPHONATE--PYRUVATE TRANSAMINASE transaminase#PC00216;transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000024608.1|UniProtKB=H2XNJ6 H2XNJ6 PTHR24126:SF14 ANKYRIN REPEAT, PH AND SEC7 DOMAIN CONTAINING PROTEIN SECG-RELATED ANK_REP_REGION DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000019463.1|UniProtKB=H2XQY5 H2XQY5 PTHR46289:SF14 52 KDA REPRESSOR OF THE INHIBITOR OF THE PROTEIN KINASE-LIKE PROTEIN-RELATED DUF4371 DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000024771.1|UniProtKB=H2XYF7 H2XYF7 LOC100176113 PTHR13479:SF66 30S RIBOSOMAL PROTEIN S18 LARGE RIBOSOMAL SUBUNIT PROTEIN ML66 structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;structural molecule activity#GO:0005198;rRNA binding#GO:0019843;binding#GO:0005488;organic cyclic compound binding#GO:0097159 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;mitochondrial gene expression#GO:0140053;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;mitochondrial translation#GO:0032543;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;mitochondrial ribosome#GO:0005761;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;ribosomal subunit#GO:0044391;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;organellar ribosome#GO:0000313;protein-containing complex#GO:0032991;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;small ribosomal subunit#GO:0015935;ribosome#GO:0005840;mitochondrial small ribosomal subunit#GO:0005763;mitochondrial protein-containing complex#GO:0098798 ribosomal protein#PC00202;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000018811.1|UniProtKB=H2XPR6 H2XPR6 PTHR13132:SF29 ALPHA- 1,6 -FUCOSYLTRANSFERASE ALPHA-(1,6)-FUCOSYLTRANSFERASE transferase activity#GO:0016740;fucosyltransferase activity#GO:0008417;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein glycosylation#GO:0006486;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein N-linked glycosylation#GO:0006487;protein metabolic process#GO:0019538;glycosylation#GO:0070085;glycoprotein metabolic process#GO:0009100;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 glycosyltransferase#PC00111 Notch signaling pathway#P00045>Neurotic#P01115 CIOIN|Ensembl=ENSCING00000019207.1|UniProtKB=H2XYD3 H2XYD3 PTHR11232:SF17 PHOSPHOTYROSINE INTERACTION DOMAIN-CONTAINING FAMILY MEMBER CAPON-LIKE PROTEIN enzyme binding#GO:0019899;protein binding#GO:0005515;binding#GO:0005488 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000003163.3|UniProtKB=F6QIK7 F6QIK7 PTHR43512:SF7 TRANSLATION FACTOR GUF1-RELATED TRANSLATION FACTOR GUF1, MITOCHONDRIAL ribonucleoprotein complex binding#GO:0043021;ribosome binding#GO:0043022;protein-containing complex binding#GO:0044877;binding#GO:0005488 positive regulation of gene expression#GO:0010628;positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of protein metabolic process#GO:0051246;regulation of amide metabolic process#GO:0034248;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;positive regulation of biosynthetic process#GO:0009891;positive regulation of protein metabolic process#GO:0051247;positive regulation of metabolic process#GO:0009893;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biosynthetic process#GO:0009889;post-transcriptional regulation of gene expression#GO:0010608;positive regulation of macromolecule biosynthetic process#GO:0010557;biological regulation#GO:0065007;regulation of translation#GO:0006417;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of biological process#GO:0048518;positive regulation of translation#GO:0045727;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 translation initiation factor#PC00224;translation factor#PC00223;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000006146.3|UniProtKB=F6V396 F6V396 PTHR24412:SF450 KELCH PROTEIN KELCH-LIKE PROTEIN DIABLO scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000019183.1|UniProtKB=H2XQM9 H2XQM9 LOC100183742 PTHR34645:SF1 SIMILAR TO HYPOTHETICAL PROTEIN GENE 136-RELATED CIOIN|Ensembl=ENSCING00000008874.3|UniProtKB=F6QY24 F6QY24 LOC100175551 PTHR10121:SF0 COATOMER SUBUNIT DELTA COATOMER SUBUNIT DELTA localization#GO:0051179;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;organelle localization#GO:0051640;establishment of localization#GO:0051234;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;transport#GO:0006810;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;coated vesicle#GO:0030135;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;vesicle coat#GO:0030120;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;Golgi-associated vesicle membrane#GO:0030660;protein-containing complex#GO:0032991;COPI vesicle coat#GO:0030126;endomembrane system#GO:0012505;membrane coat#GO:0030117;coated vesicle membrane#GO:0030662;COPI-coated vesicle#GO:0030137;Golgi-associated vesicle#GO:0005798;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;coated membrane#GO:0048475;cytoplasmic vesicle membrane#GO:0030659 vesicle coat protein#PC00235 CIOIN|Ensembl=ENSCING00000007075.3|UniProtKB=F6WVX7 F6WVX7 PTHR16036:SF2 ANKYRIN REPEAT AND ZINC FINGER DOMAIN-CONTAINING PROTEIN 1 TRNA ENDONUCLEASE ANKZF1 response to organic substance#GO:0010033;macromolecule catabolic process#GO:0009057;cellular response to stimulus#GO:0051716;response to endoplasmic reticulum stress#GO:0034976;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;response to organonitrogen compound#GO:0010243;ERAD pathway#GO:0036503;cellular process#GO:0009987;primary metabolic process#GO:0044238;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;cellular response to stress#GO:0033554;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 CIOIN|Ensembl=ENSCING00000002141.3|UniProtKB=F6W4W6 F6W4W6 PTHR11977:SF131 VILLIN GELSOLIN-LIKE DOMAIN-CONTAINING PROTEIN cytoskeletal protein binding#GO:0008092;phosphatidylinositol bisphosphate binding#GO:1902936;small molecule binding#GO:0036094;phosphatidylinositol-4,5-bisphosphate binding#GO:0005546;binding#GO:0005488;actin filament binding#GO:0051015;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;lipid binding#GO:0008289;ion binding#GO:0043167;phosphatidylinositol binding#GO:0035091;anion binding#GO:0043168;phosphatidylinositol phosphate binding#GO:1901981;phospholipid binding#GO:0005543;actin binding#GO:0003779 negative regulation of protein polymerization#GO:0032272;negative regulation of protein depolymerization#GO:1901880;negative regulation of biological process#GO:0048519;negative regulation of actin filament depolymerization#GO:0030835;regulation of cellular component organization#GO:0051128;regulation of actin polymerization or depolymerization#GO:0008064;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;actin filament-based process#GO:0030029;regulation of protein-containing complex assembly#GO:0043254;regulation of biological quality#GO:0065008;regulation of cellular component biogenesis#GO:0044087;supramolecular fiber organization#GO:0097435;negative regulation of organelle organization#GO:0010639;negative regulation of protein-containing complex disassembly#GO:0043242;actin filament organization#GO:0007015;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;regulation of actin filament-based process#GO:0032970;barbed-end actin filament capping#GO:0051016;negative regulation of cellular component organization#GO:0051129;regulation of protein polymerization#GO:0032271;negative regulation of cellular process#GO:0048523;regulation of anatomical structure size#GO:0090066;regulation of actin filament length#GO:0030832;regulation of organelle organization#GO:0033043;regulation of actin filament organization#GO:0110053;actin polymerization or depolymerization#GO:0008154;regulation of protein-containing complex disassembly#GO:0043244;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of actin filament polymerization#GO:0030833;regulation of cellular component size#GO:0032535;negative regulation of supramolecular fiber organization#GO:1902904;regulation of supramolecular fiber organization#GO:1902903;cellular component organization or biogenesis#GO:0071840;regulation of protein depolymerization#GO:1901879;organelle organization#GO:0006996;regulation of actin filament depolymerization#GO:0030834;regulation of cellular process#GO:0050794;negative regulation of actin filament polymerization#GO:0030837;biological regulation#GO:0065007;negative regulation of protein-containing complex assembly#GO:0031333;actin cytoskeleton organization#GO:0030036;negative regulation of cytoskeleton organization#GO:0051494 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-motor actin binding protein#PC00165 CIOIN|Ensembl=ENSCING00000014695.2|UniProtKB=F6ZCI6 F6ZCI6 LOC100186932 PTHR12771:SF51 ENGULFMENT AND CELL MOTILITY LD01482P scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000001342.3|UniProtKB=A0A1W3JPJ7 A0A1W3JPJ7 LOC100178056 PTHR10644:SF1 DNA REPAIR/RNA PROCESSING CPSF FAMILY SPLICING FACTOR 3B SUBUNIT 3 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;snRNA binding#GO:0017069;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704 ribonucleoprotein complex#GO:1990904;spliceosomal snRNP complex#GO:0097525;small nuclear ribonucleoprotein complex#GO:0030532;protein-containing complex#GO:0032991;U2 snRNP#GO:0005686;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA processing factor#PC00147 CIOIN|Ensembl=ENSCING00000007869.3|UniProtKB=F6U4V1 F6U4V1 LOC100176463 PTHR10953:SF4 UBIQUITIN-ACTIVATING ENZYME E1 UBIQUITIN-ACTIVATING ENZYME E1 C-TERMINAL DOMAIN-CONTAINING PROTEIN ligase activity#GO:0016874;transferase activity#GO:0016740;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877;nucleotidyltransferase activity#GO:0016779;thiosulfate sulfurtransferase activity#GO:0004792;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity, acting on a protein#GO:0140096;sulfurtransferase activity#GO:0016783 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;cellular response to stimulus#GO:0051716;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;cellular process#GO:0009987;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;response to stimulus#GO:0050896;DNA damage response#GO:0006974;response to stress#GO:0006950;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;cellular response to stress#GO:0033554;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 Ubiquitin proteasome pathway#P00060>E1#P01492 CIOIN|Ensembl=ENSCING00000007458.3|UniProtKB=F6YIV7 F6YIV7 xbpd PTHR46542:SF1 X-BOX BINDING PROTEIN 1 X-BOX BINDING PROTEIN 1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000011665.2|UniProtKB=F6X941 F6X941 PTHR13491:SF0 ZCCHC10 PROTEIN ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 10 CIOIN|Ensembl=ENSCING00000001889.3|UniProtKB=Q4H2U5 Q4H2U5 Ci-sFRP1_5 PTHR11309:SF148 FRIZZLED SECRETED FRIZZLED-RELATED PROTEIN 1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;protein binding#GO:0005515;Wnt-protein binding#GO:0017147;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;non-canonical Wnt signaling pathway#GO:0035567;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;cell-cell signaling by wnt#GO:0198738;canonical Wnt signaling pathway#GO:0060070;cell-cell signaling#GO:0007267;signaling#GO:0023052;Wnt signaling pathway#GO:0016055 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;extracellular space#GO:0005615;membrane#GO:0016020;extracellular region#GO:0005576;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 CIOIN|Ensembl=ENSCING00000002732.3|UniProtKB=F7ALU0 F7ALU0 PTHR12287:SF23 EPIDERMAL GROWTH FACTOR RECEPTOR KINASE SUBSTRATE EPS8-RELATED PROTEIN AROUSER, ISOFORM A-RELATED cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;actin binding#GO:0003779;binding#GO:0005488 regulation of cell communication#GO:0010646;regulation of Rho protein signal transduction#GO:0035023;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;small GTPase-mediated signal transduction#GO:0007264;regulation of signaling#GO:0023051;cell communication#GO:0007154;cellular process#GO:0009987;regulation of intracellular signal transduction#GO:1902531;Rho protein signal transduction#GO:0007266;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;intracellular signal transduction#GO:0035556;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000011276.2|UniProtKB=F6YSP8 F6YSP8 LOC100184198 PTHR11532:SF62 PROTEASE M14 CARBOXYPEPTIDASE CARBOXYPEPTIDASE D metalloexopeptidase activity#GO:0008235;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;metallocarboxypeptidase activity#GO:0004181;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;carboxypeptidase activity#GO:0004180 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;protein processing#GO:0016485;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 protease#PC00190;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000018988.1|UniProtKB=H2XS14 H2XS14 LOC100186682 PTHR45618:SF13 MITOCHONDRIAL DICARBOXYLATE CARRIER-RELATED MITOCHONDRIAL DICARBOXYLATE CARRIER inorganic molecular entity transmembrane transporter activity#GO:0015318;secondary active transmembrane transporter activity#GO:0015291;antiporter activity#GO:0015297;transmembrane transporter activity#GO:0022857;succinate transmembrane transporter activity#GO:0015141;carboxylic acid transmembrane transporter activity#GO:0046943;organic acid transmembrane transporter activity#GO:0005342;inorganic anion transmembrane transporter activity#GO:0015103;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 succinate transport#GO:0015744;transmembrane transport#GO:0055085;dicarboxylic acid transport#GO:0006835;organic anion transport#GO:0015711;organic acid transport#GO:0015849;transport#GO:0006810;carboxylic acid transport#GO:0046942;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;carboxylic acid transmembrane transport#GO:1905039;inorganic anion transmembrane transport#GO:0098661;localization#GO:0051179;organic substance transport#GO:0071702;phosphate ion transport#GO:0006817;establishment of localization#GO:0051234;C4-dicarboxylate transport#GO:0015740;organic acid transmembrane transport#GO:1903825;inorganic anion transport#GO:0015698 secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000011876.2|UniProtKB=F6Z1X8 F6Z1X8 LOC100180823 PTHR24305:SF166 CYTOCHROME P450 CYTOCHROME P450 12A4, MITOCHONDRIAL-RELATED oxygenase#PC00177 CIOIN|Ensembl=ENSCING00000007947.3|UniProtKB=F6Z8I7 F6Z8I7 PTHR19969:SF14 SH2-SH3 ADAPTOR PROTEIN-RELATED DREADLOCKS, ISOFORM B molecular adaptor activity#GO:0060090;signaling adaptor activity#GO:0035591;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;protein tyrosine kinase binding#GO:1990782;receptor tyrosine kinase binding#GO:0030971;signaling receptor binding#GO:0005102;kinase binding#GO:0019900 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cell motility#GO:0048870;cellular process#GO:0009987;cell migration#GO:0016477;signaling#GO:0023052;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000001098.3|UniProtKB=F7AGL2 F7AGL2 PTHR19134:SF553 RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE TYROSINE-PROTEIN PHOSPHATASE 10D-RELATED hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;protein tyrosine phosphatase activity#GO:0004725;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 protein phosphatase#PC00195;protein modifying enzyme#PC00260 Axon guidance mediated by Slit/Robo#P00008>Ptp10D#P00343 CIOIN|Ensembl=ENSCING00000001888.3|UniProtKB=F6SIX8 F6SIX8 PTHR45903:SF1 GLUTAMATE-RICH WD REPEAT-CONTAINING PROTEIN 1 GLUTAMATE-RICH WD REPEAT-CONTAINING PROTEIN 1 cellular component organization or biogenesis#GO:0071840;cellular component biogenesis#GO:0044085;ribosome biogenesis#GO:0042254;cellular process#GO:0009987;ribonucleoprotein complex biogenesis#GO:0022613 membrane-enclosed lumen#GO:0031974;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000010780.3|UniProtKB=F6TMJ9 F6TMJ9 LOC100177596 PTHR24031:SF84 RNA HELICASE EUKARYOTIC INITIATION FACTOR 4A nucleic acid binding#GO:0003676;translation regulator activity#GO:0045182;translation regulator activity, nucleic acid binding#GO:0090079;binding#GO:0005488;organic cyclic compound binding#GO:0097159;translation initiation factor activity#GO:0003743;translation factor activity, RNA binding#GO:0008135 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cytoplasmic translation#GO:0002181;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cytoplasmic translational initiation#GO:0002183;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;translational initiation#GO:0006413;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;cytoplasmic stress granule#GO:0010494;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464;intracellular anatomical structure#GO:0005622 RNA helicase#PC00032 CIOIN|Ensembl=ENSCING00000022550.1|UniProtKB=H2XQ27 H2XQ27 PTHR12241:SF154 TUBULIN POLYGLUTAMYLASE TUBULIN POLYGLUTAMYLASE TTLL11 cytoskeletal protein binding#GO:0008092;ligase activity#GO:0016874;protein binding#GO:0005515;tubulin binding#GO:0015631;catalytic activity, acting on a protein#GO:0140096;binding#GO:0005488;catalytic activity#GO:0003824 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;microtubule cytoskeleton organization#GO:0000226;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;cellular component organization#GO:0016043;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;nitrogen compound metabolic process#GO:0006807;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;microtubule cytoskeleton#GO:0015630;ciliary basal body#GO:0036064;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;cilium#GO:0005929;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;microtubule or microtubule-binding cytoskeletal protein#PC00157 CIOIN|Ensembl=ENSCING00000015984.2|UniProtKB=F7AHJ7 F7AHJ7 LOC100181338 PTHR33444:SF2 SI:DKEY-19B23.12-RELATED MARVEL DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000008155.3|UniProtKB=F6VFA0 F6VFA0 LOC100179536 PTHR45722:SF2 60S RIBOSOMAL PROTEIN L35 LARGE RIBOSOMAL SUBUNIT PROTEIN UL29-RELATED structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;structural molecule activity#GO:0005198;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;RNA processing#GO:0006396;gene expression#GO:0010467;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;ribosomal large subunit biogenesis#GO:0042273;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;maturation of LSU-rRNA#GO:0000470;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic large ribosomal subunit#GO:0022625;large ribosomal subunit#GO:0015934;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000023187.1|UniProtKB=H2XNV5 H2XNV5 PTHR11915:SF442 SPECTRIN/FILAMIN RELATED CYTOSKELETAL PROTEIN ALPHA-ACTININ, SARCOMERIC-RELATED cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actin filament-based process#GO:0030029;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987;organelle organization#GO:0006996 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cortical cytoskeleton#GO:0030863;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;cell cortex#GO:0005938;cell periphery#GO:0071944;cortical actin cytoskeleton#GO:0030864;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 Integrin signalling pathway#P00034>alpha actinin#P00928 CIOIN|Ensembl=ENSCING00000002154.3|UniProtKB=Q8T8A6 Q8T8A6 Ci-CSD PTHR45677:SF8 GLUTAMATE DECARBOXYLASE-RELATED CYSTEINE SULFINIC ACID DECARBOXYLASE lyase activity#GO:0016829;carboxy-lyase activity#GO:0016831;carbon-carbon lyase activity#GO:0016830;catalytic activity#GO:0003824 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 decarboxylase#PC00089 Gamma-aminobutyric acid synthesis#P04384>Glutamate decarboxylase#P04482 CIOIN|Ensembl=ENSCING00000009592.3|UniProtKB=F7AXB1 F7AXB1 PTHR23113:SF368 GUANINE NUCLEOTIDE EXCHANGE FACTOR CELL DIVISION CONTROL PROTEIN 25 nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;small GTPase-mediated signal transduction#GO:0007264;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;Ras protein signal transduction#GO:0007265;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 PDGF signaling pathway#P00047>SOS#P01159;EGF receptor signaling pathway#P00018>SOS#P00558 CIOIN|Ensembl=ENSCING00000014546.2|UniProtKB=F6UZR0 F6UZR0 PTHR22597:SF0 POLYCOMB GROUP PROTEIN POLYCOMB PROTEIN SUZ12 nucleic acid binding#GO:0003676;protein-containing complex binding#GO:0044877;chromatin DNA binding#GO:0031490;chromatin binding#GO:0003682;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 CIOIN|Ensembl=ENSCING00000006671.3|UniProtKB=F6SR69 F6SR69 PTHR11690:SF222 AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED AMILORIDE-SENSITIVE SODIUM CHANNEL SUBUNIT GAMMA monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;ligand-gated monoatomic cation channel activity#GO:0099094;sodium channel activity#GO:0005272;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;ligand-gated channel activity#GO:0022834 localization#GO:0051179;sodium ion transport#GO:0006814;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;monoatomic cation transport#GO:0006812;inorganic ion transmembrane transport#GO:0098660;monoatomic ion transport#GO:0006811;cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;sodium ion transmembrane transport#GO:0035725 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 CIOIN|Ensembl=ENSCING00000021810.1|UniProtKB=H2XNI7 H2XNI7 PTHR12461:SF106 HYPOXIA-INDUCIBLE FACTOR 1 ALPHA INHIBITOR-RELATED BIFUNCTIONAL PEPTIDASE AND ARGINYL-HYDROXYLASE JMJD5 protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000005309.3|UniProtKB=F7BBL9 F7BBL9 PTHR11848:SF119 TGF-BETA FAMILY TGF-BETA FAMILY PROFILE DOMAIN-CONTAINING PROTEIN molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;cytokine activity#GO:0005125;protein binding#GO:0005515;signaling receptor binding#GO:0005102 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 TGF-beta signaling pathway#P00052>TGFbeta#P01286 CIOIN|Ensembl=ENSCING00000013555.2|UniProtKB=F6YC34 F6YC34 PTHR21623:SF2 SPERIOLIN-BINDING FACTOR COILED-COIL DOMAIN-CONTAINING PROTEIN 33 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;microbody#GO:0042579;peroxisome#GO:0005777;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000000226.3|UniProtKB=F6T385 F6T385 LOC100178236 PTHR12217:SF4 EUKARYOTIC TRANSLATION INITIATION FACTOR 2D EUKARYOTIC TRANSLATION INITIATION FACTOR 2D nucleic acid binding#GO:0003676;translation regulator activity#GO:0045182;translation regulator activity, nucleic acid binding#GO:0090079;binding#GO:0005488;organic cyclic compound binding#GO:0097159;translation initiation factor activity#GO:0003743;translation factor activity, RNA binding#GO:0008135 cellular component biogenesis#GO:0044085;peptide metabolic process#GO:0006518;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;translation#GO:0006412;protein-RNA complex assembly#GO:0022618;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular component assembly#GO:0022607;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cytoplasmic translation#GO:0002181;cellular component organization#GO:0016043;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;cytoplasmic translational initiation#GO:0002183;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;cellular component organization or biogenesis#GO:0071840;peptide biosynthetic process#GO:0043043;protein-containing complex organization#GO:0043933;ribonucleoprotein complex biogenesis#GO:0022613;translational initiation#GO:0006413;protein-RNA complex organization#GO:0071826 translation initiation factor#PC00224;translation factor#PC00223;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000004407.3|UniProtKB=F6YNQ3 F6YNQ3 PTHR11835:SF42 DECARBOXYLATING DEHYDROGENASES-ISOCITRATE, ISOPROPYLMALATE, TARTRATE ISOCITRATE DEHYDROGENASE [NAD] SUBUNIT BETA, MITOCHONDRIAL oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 organic hydroxy compound metabolic process#GO:1901615;oxoacid metabolic process#GO:0043436;aerobic respiration#GO:0009060;cellular respiration#GO:0045333;generation of precursor metabolites and energy#GO:0006091;cellular metabolic process#GO:0044237;alcohol metabolic process#GO:0006066;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;energy derivation by oxidation of organic compounds#GO:0015980;tricarboxylic acid cycle#GO:0006099;primary metabolic process#GO:0044238;secondary alcohol metabolic process#GO:1902652;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 dehydrogenase#PC00092;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000002221.3|UniProtKB=F6Z7A4 F6Z7A4 PTHR22106:SF5 COILED-COIL DOMAIN-CONTAINING PROTEIN 78 COILED-COIL DOMAIN-CONTAINING PROTEIN 78 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000003967.3|UniProtKB=A0A1W2WD17 A0A1W2WD17 LOC100182527 PTHR46511:SF1 MORN REPEAT-CONTAINING PROTEIN 3 MORN REPEAT-CONTAINING PROTEIN 3 CIOIN|Ensembl=ENSCING00000013222.2|UniProtKB=F6V526 F6V526 LOC100175991 PTHR12121:SF34 CARBON CATABOLITE REPRESSOR PROTEIN 4 PROTEIN ANGEL catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters#GO:0016796;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity#GO:0016787;3'-5'-RNA exonuclease activity#GO:0000175;exonuclease activity#GO:0004527;3'-5' exonuclease activity#GO:0008408;RNA nuclease activity#GO:0004540 mRNA polyadenylation factor#PC00146 CIOIN|Ensembl=ENSCING00000008177.3|UniProtKB=F6PP23 F6PP23 zf(fyve)-4 PTHR12673:SF241 FACIOGENITAL DYSPLASIA PROTEIN DH DOMAIN-CONTAINING PROTEIN nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cell projection organization#GO:0030030;organelle organization#GO:0006996;filopodium assembly#GO:0046847;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 CIOIN|Ensembl=ENSCING00000019763.1|UniProtKB=A0A1W5BEL0 A0A1W5BEL0 LOC100181168 PTHR24034:SF204 EGF-LIKE DOMAIN-CONTAINING PROTEIN ADHESION G PROTEIN-COUPLED RECEPTOR E1 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 CIOIN|Ensembl=ENSCING00000000384.3|UniProtKB=F6SF06 F6SF06 PTHR43329:SF141 EPOXIDE HYDROLASE AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN-RELATED hydrolase activity#GO:0016787;catalytic activity#GO:0003824 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000006681.3|UniProtKB=F6YPX6 F6YPX6 PTHR24412:SF450 KELCH PROTEIN KELCH-LIKE PROTEIN DIABLO scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000018436.1|UniProtKB=H2XYQ2 H2XYQ2 PTHR15276:SF0 H4 D10S170 PROTEIN-RELATED COILED-COIL DOMAIN-CONTAINING PROTEIN 6 CIOIN|Ensembl=ENSCING00000007094.3|UniProtKB=F6W8L4 F6W8L4 LOC100175011 PTHR23426:SF76 FERREDOXIN/ADRENODOXIN ADRENODOXIN-LIKE PROTEIN 2, MITOCHONDRIAL cellular metabolic process#GO:0044237;electron transport chain#GO:0022900;cellular process#GO:0009987;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 oxidoreductase#PC00176 Vitamin D metabolism and pathway#P04396>FDX#P04607 CIOIN|Ensembl=ENSCING00000021248.1|UniProtKB=A0A1W2WKT4 A0A1W2WKT4 LOC100184857 PTHR11831:SF5 30S 40S RIBOSOMAL PROTEIN 40S RIBOSOMAL PROTEIN S9 structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;structural molecule activity#GO:0005198;binding#GO:0005488;organic cyclic compound binding#GO:0097159;rRNA binding#GO:0019843 cellular component organization or biogenesis#GO:0071840;cellular component biogenesis#GO:0044085;ribosome biogenesis#GO:0042254;cellular process#GO:0009987;ribosomal small subunit biogenesis#GO:0042274;ribonucleoprotein complex biogenesis#GO:0022613 intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;small ribosomal subunit#GO:0015935;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;ribosomal subunit#GO:0044391 ribosomal protein#PC00202 CIOIN|Ensembl=ENSCING00000007422.3|UniProtKB=F7B7Y1 F7B7Y1 PTHR23317:SF76 DEDICATOR OF CYTOKINESIS DOCK LD20667P nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 regulation of molecular function#GO:0065009;regulation of GTPase activity#GO:0043087;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;biological regulation#GO:0065007;positive regulation of molecular function#GO:0044093;regulation of hydrolase activity#GO:0051336;regulation of catalytic activity#GO:0050790;positive regulation of hydrolase activity#GO:0051345 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022 CIOIN|Ensembl=ENSCING00000003804.3|UniProtKB=F7ABK2 F7ABK2 zf(bbox_ring)-4 PTHR11711:SF163 ADP RIBOSYLATION FACTOR-RELATED E3 UBIQUITIN-PROTEIN LIGASE TRIM23 carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167 cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 bounding membrane of organelle#GO:0098588;lytic vacuole membrane#GO:0098852;intracellular membrane-bounded organelle#GO:0043231;vacuolar membrane#GO:0005774;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;lytic vacuole#GO:0000323;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;lysosomal membrane#GO:0005765;lysosome#GO:0005764;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 G-protein#PC00020 CIOIN|Ensembl=ENSCING00000020612.1|UniProtKB=H2XX28 H2XX28 PTHR48034:SF6 TRANSFORMER-2 SEX-DETERMINING PROTEIN-RELATED TRANSFORMER-2 SEX-DETERMINING PROTEIN nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 positive regulation of gene expression#GO:0010628;positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of mRNA metabolic process#GO:1903313;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;biological regulation#GO:0065007;regulation of mRNA processing#GO:0050684;regulation of gene expression#GO:0010468;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule biosynthetic process#GO:0010556;regulation of mRNA splicing, via spliceosome#GO:0048024;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000021418.1|UniProtKB=H2XK87 H2XK87 PTHR12232:SF15 SH3 DOMAIN-BINDING GLUTAMIC ACID-RICH-LIKE PROTEIN SH3 DOMAIN-BINDING GLUTAMIC ACID-RICH PROTEIN HOMOLOG cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000014325.2|UniProtKB=F6TZP7 F6TZP7 LOC100181625 PTHR31097:SF2 SI:DKEY-276J7.1 CHROMOSOME 7 OPEN READING FRAME 57 CIOIN|Ensembl=ENSCING00000004763.3|UniProtKB=A0A1W2WIN8 A0A1W2WIN8 LOC100180425 PTHR13318:SF165 PARTNER OF PAIRED, ISOFORM B-RELATED F-BOX_LRR-REPEAT PROTEIN FBXL-1 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 SCF ubiquitin ligase complex#GO:0019005;intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;cullin-RING ubiquitin ligase complex#GO:0031461;transferase complex#GO:1990234 CIOIN|Ensembl=ENSCING00000020744.1|UniProtKB=H2Y115 H2Y115 PTHR24072:SF142 RHO FAMILY GTPASE RHOU, ISOFORM B GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;enzyme binding#GO:0019899;ribonucleoside triphosphate phosphatase activity#GO:0017111;kinase binding#GO:0019900;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;protein kinase binding#GO:0019901;anion binding#GO:0043168;ion binding#GO:0043167 establishment or maintenance of cell polarity#GO:0007163;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;small GTPase-mediated signal transduction#GO:0007264;transport#GO:0006810;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cell communication#GO:0007154;cellular process#GO:0009987;Rho protein signal transduction#GO:0007266;localization#GO:0051179;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;establishment of cell polarity#GO:0030010;establishment of localization#GO:0051234;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;intracellular signal transduction#GO:0035556;import into cell#GO:0098657;signaling#GO:0023052 small GTPase#PC00208 CIOIN|Ensembl=ENSCING00000001919.3|UniProtKB=F6ZJ65 F6ZJ65 LOC100185857 PTHR35087:SF1 SIMILAR TO HYPOTHETICAL PROTEIN FLJ40298 RIKEN CDNA 4930505A04 GENE CIOIN|Ensembl=ENSCING00000001202.3|UniProtKB=F6SZ23 F6SZ23 LOC778964 PTHR24416:SF566 TYROSINE-PROTEIN KINASE RECEPTOR EPIDERMAL GROWTH FACTOR RECEPTOR signaling receptor activity#GO:0038023;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;molecular transducer activity#GO:0060089;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672;transmembrane signaling receptor activity#GO:0004888 negative regulation of biological process#GO:0048519;signal transduction#GO:0007165;neurogenesis#GO:0022008;regulation of phosphate metabolic process#GO:0019220;positive regulation of cellular metabolic process#GO:0031325;developmental process#GO:0032502;positive regulation of molecular function#GO:0044093;positive regulation of cell population proliferation#GO:0008284;regulation of catalytic activity#GO:0050790;nervous system development#GO:0007399;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;system development#GO:0048731;cell differentiation#GO:0030154;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;negative regulation of programmed cell death#GO:0043069;regulation of molecular function#GO:0065009;positive regulation of biological process#GO:0048518;negative regulation of cellular process#GO:0048523;signaling#GO:0023052;regulation of programmed cell death#GO:0043067;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;cellular developmental process#GO:0048869;positive regulation of phosphorylation#GO:0042327;cellular response to stimulus#GO:0051716;regulation of apoptotic process#GO:0042981;regulation of cell population proliferation#GO:0042127;positive regulation of catalytic activity#GO:0043085;multicellular organism development#GO:0007275;positive regulation of phosphorus metabolic process#GO:0010562;cell communication#GO:0007154;cellular process#GO:0009987;negative regulation of apoptotic process#GO:0043066;positive regulation of cellular process#GO:0048522;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphate metabolic process#GO:0045937;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;anatomical structure development#GO:0048856;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;multicellular organismal process#GO:0032501;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 basal plasma membrane#GO:0009925;receptor complex#GO:0043235;protein-containing complex#GO:0032991;plasma membrane region#GO:0098590;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;basal part of cell#GO:0045178;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 EGF receptor signaling pathway#P00018>EGFR#P00542;Cadherin signaling pathway#P00012>EGFR#P00466 CIOIN|Ensembl=ENSCING00000009611.3|UniProtKB=F7AD29 F7AD29 LOC100179207 PTHR12390:SF0 UROPORPHYRINOGEN III SYNTHASE UROPORPHYRINOGEN-III SYNTHASE lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835;hydro-lyase activity#GO:0016836;catalytic activity#GO:0003824 tetrapyrrole metabolic process#GO:0033013;cellular aromatic compound metabolic process#GO:0006725;organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;porphyrin-containing compound metabolic process#GO:0006778;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;carboxylic acid biosynthetic process#GO:0046394;heterocycle biosynthetic process#GO:0018130;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;aromatic compound biosynthetic process#GO:0019438;small molecule biosynthetic process#GO:0044283;carboxylic acid metabolic process#GO:0019752;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 hydrolase#PC00121 Heme biosynthesis#P02746>Uroporphyrinogen-III synthase#P02974 CIOIN|Ensembl=ENSCING00000007557.3|UniProtKB=F6T8B2 F6T8B2 LOC100175813 PTHR12480:SF41 ARGININE DEMETHYLASE AND LYSYL-HYDROXYLASE JMJD JMJC DOMAIN-CONTAINING PROTEIN sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;dioxygenase activity#GO:0051213;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity#GO:0016491 positive regulation of gene expression#GO:0010628;positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of protein metabolic process#GO:0051246;regulation of amide metabolic process#GO:0034248;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;protein modification process#GO:0036211;regulation of cellular component organization#GO:0051128;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;protein hydroxylation#GO:0018126;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;positive regulation of biological process#GO:0048518;positive regulation of translation#GO:0045727;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;regulation of protein-containing complex disassembly#GO:0043244;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;positive regulation of protein metabolic process#GO:0051247;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;post-transcriptional regulation of gene expression#GO:0010608;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;regulation of translation#GO:0006417;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000019266.1|UniProtKB=H2Y0P5 H2Y0P5 PTHR24372:SF77 GLYCOPROTEIN HORMONE RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 response to organic substance#GO:0010033;positive regulation of adenylate cyclase activity#GO:0045762;regulation of lyase activity#GO:0051339;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;cellular response to stimulus#GO:0051716;regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;cellular response to endogenous stimulus#GO:0071495;cellular response to chemical stimulus#GO:0070887;positive regulation of catalytic activity#GO:0043085;cellular response to organic substance#GO:0071310;regulation of cyclase activity#GO:0031279;positive regulation of molecular function#GO:0044093;cell communication#GO:0007154;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;positive regulation of cyclase activity#GO:0031281;hormone-mediated signaling pathway#GO:0009755;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to endogenous stimulus#GO:0009719;response to hormone#GO:0009725;cellular response to hormone stimulus#GO:0032870;response to chemical#GO:0042221;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of lyase activity#GO:0051349;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 CIOIN|Ensembl=ENSCING00000004857.3|UniProtKB=F6TC91 F6TC91 PTHR23318:SF0 ATP SYNTHASE GAMMA-RELATED SERINE_THREONINE-PROTEIN PHOSPHATASE 4 REGULATORY SUBUNIT 3 phosphatase regulator activity#GO:0019208;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;protein phosphatase regulator activity#GO:0019888 macromolecule modification#GO:0043412;nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;dephosphorylation#GO:0016311;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein dephosphorylation#GO:0006470;cellular metabolic process#GO:0044237;protein metabolic process#GO:0019538;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;protein serine/threonine phosphatase complex#GO:0008287;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ATP synthase#PC00002;primary active transporter#PC00068;transporter#PC00227 CIOIN|Ensembl=ENSCING00000014124.2|UniProtKB=F6SQY7 F6SQY7 PTHR43888:SF10 DNAJ-LIKE-2, ISOFORM A-RELATED DNAJ-LIKE-2, ISOFORM A protein binding#GO:0005515;protein-folding chaperone binding#GO:0051087;binding#GO:0005488 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein folding#GO:0006457;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 chaperone#PC00072 CIOIN|Ensembl=ENSCING00000024102.1|UniProtKB=H2Y1N7 H2Y1N7 gpx_d PTHR11592:SF78 GLUTATHIONE PEROXIDASE GLUTATHIONE PEROXIDASE peroxidase#PC00180;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000003630.3|UniProtKB=F6TJY9 F6TJY9 PTHR10442:SF0 40S RIBOSOMAL PROTEIN S21 SMALL RIBOSOMAL SUBUNIT PROTEIN ES21 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;RNA processing#GO:0006396;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;ribosome biogenesis#GO:0042254;maturation of 5.8S rRNA#GO:0000460;endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000447;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA 3'-end processing#GO:0031123;macromolecule metabolic process#GO:0043170;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;maturation of SSU-rRNA#GO:0030490;ribosomal small subunit biogenesis#GO:0042274 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic small ribosomal subunit#GO:0022627;cytosol#GO:0005829;small ribosomal subunit#GO:0015935;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000003156.3|UniProtKB=F6QIW3 F6QIW3 PTHR23308:SF66 NUCLEAR INHIBITOR OF PROTEIN PHOSPHATASE-1 KANADAPTIN nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 RNA splicing factor#PC00148;RNA processing factor#PC00147 CIOIN|Ensembl=ENSCING00000023716.1|UniProtKB=H2Y3T4 H2Y3T4 LOC100176205 PTHR13250:SF1 TF-1 CELL APOPTOSIS RELATED PROTEIN-15 PROGRAMMED CELL DEATH PROTEIN 10 enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;binding#GO:0005488;kinase binding#GO:0019900 positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;regulation of cellular component organization#GO:0051128;regulation of catalytic activity#GO:0050790;positive regulation of protein modification process#GO:0031401;regulation of intracellular signal transduction#GO:1902531;positive regulation of MAPK cascade#GO:0043410;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;positive regulation of response to stimulus#GO:0048584;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;regulation of protein serine/threonine kinase activity#GO:0071900;positive regulation of intracellular signal transduction#GO:1902533;regulation of MAP kinase activity#GO:0043405;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;regulation of kinase activity#GO:0043549;positive regulation of protein phosphorylation#GO:0001934;regulation of protein kinase activity#GO:0045859;regulation of cell communication#GO:0010646;positive regulation of phosphorylation#GO:0042327;positive regulation of catalytic activity#GO:0043085;regulation of organelle organization#GO:0033043;positive regulation of phosphorus metabolic process#GO:0010562;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of protein serine/threonine kinase activity#GO:0071902;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;regulation of primary metabolic process#GO:0080090;positive regulation of protein metabolic process#GO:0051247;positive regulation of phosphate metabolic process#GO:0045937;positive regulation of protein kinase activity#GO:0045860;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of protein phosphorylation#GO:0001932;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991 CIOIN|Ensembl=ENSCING00000008826.2|UniProtKB=A0A1W5B9L1 A0A1W5B9L1 LOC100187256 PTHR21860:SF2 TRANSCRIPTION INITIATION FACTOR IIIC TFIIIC , POLYPEPTIDE 6-RELATED GENERAL TRANSCRIPTION FACTOR 3C POLYPEPTIDE 6 cellular aromatic compound metabolic process#GO:0006725;DNA-templated transcription#GO:0006351;heterocycle metabolic process#GO:0046483;transcription by RNA polymerase III#GO:0006383;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;gene expression#GO:0010467;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;aromatic compound biosynthetic process#GO:0019438;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;transcription factor TFIIIC complex#GO:0000127 CIOIN|Ensembl=ENSCING00000021005.1|UniProtKB=H2XVD0 H2XVD0 PTHR15592:SF27 MATRIN 3/NUCLEAR PROTEIN 220-RELATED HEPHAESTUS, ISOFORM Y nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nitrogen compound metabolic process#GO:0051171;regulation of biosynthetic process#GO:0009889;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA metabolic process#GO:0051252;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA processing factor#PC00147;RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000002420.3|UniProtKB=F6QHS0 F6QHS0 PTHR44156:SF15 SUPERNUMERARY LIMBS, ISOFORM B-RELATED F-BOX DOMAIN-CONTAINING PROTEIN ubiquitin ligase-substrate adaptor activity#GO:1990756;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein polyubiquitination#GO:0000209;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 SCF ubiquitin ligase complex#GO:0019005;intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;cullin-RING ubiquitin ligase complex#GO:0031461;transferase complex#GO:1990234 CIOIN|Ensembl=ENSCING00000009139.3|UniProtKB=F7BBN7 F7BBN7 PTHR18934:SF118 ATP-DEPENDENT RNA HELICASE ATP-DEPENDENT RNA HELICASE DHX33 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;helicase activity#GO:0004386;ATP-dependent activity#GO:0140657;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;catalytic activity, acting on a nucleic acid#GO:0140640;double-stranded RNA binding#GO:0003725 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of transcription by RNA polymerase I#GO:0045943;regulation of transcription by RNA polymerase I#GO:0006356;positive regulation of RNA biosynthetic process#GO:1902680;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of RNA biosynthetic process#GO:2001141;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of RNA metabolic process#GO:0051254;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA helicase#PC00032 CIOIN|Ensembl=ENSCING00000007936.3|UniProtKB=F6ZRQ5 F6ZRQ5 PTHR31488:SF1 DPY-19-LIKE 1, LIKE (H. SAPIENS) C-MANNOSYLTRANSFERASE DPY19L1 mannosyltransferase activity#GO:0000030;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;protein mannosylation#GO:0035268;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085;mannosylation#GO:0097502 envelope#GO:0031975;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;organelle membrane#GO:0031090;organelle inner membrane#GO:0019866;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;nuclear membrane#GO:0031965;endomembrane system#GO:0012505;nuclear inner membrane#GO:0005637;membrane-bounded organelle#GO:0043227 CIOIN|Ensembl=ENSCING00000002945.3|UniProtKB=F6R8R2 F6R8R2 PTHR10157:SF23 DOPAMINE BETA HYDROXYLASE RELATED MOXD1 HOMOLOG 1 hydroxylase#PC00122 CIOIN|Ensembl=ENSCING00000014261.2|UniProtKB=F6U6T9 F6U6T9 LOC100178473 PTHR21240:SF27 2-AMINO-3-CARBOXYLMUCONATE-6-SEMIALDEHYDE DECARBOXYLASE 2-AMINO-3-CARBOXYMUCONATE-6-SEMIALDEHYDE DECARBOXYLASE secondary metabolic process#GO:0019748;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 decarboxylase#PC00089;lyase#PC00144 CIOIN|Ensembl=ENSCING00000008299.3|UniProtKB=F6QC45 F6QC45 LOC100176668 PTHR22811:SF50 TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN 2 endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;Golgi organization#GO:0007030;macromolecule localization#GO:0033036;transport#GO:0006810;endomembrane system organization#GO:0010256;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;organelle organization#GO:0006996;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 COPII-coated ER to Golgi transport vesicle#GO:0030134;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;cellular anatomical entity#GO:0110165;organelle#GO:0043226;coated vesicle#GO:0030135;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;endoplasmic reticulum#GO:0005783;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793 vesicle coat protein#PC00235 CIOIN|Ensembl=ENSCING00000022336.1|UniProtKB=H2XSM0 H2XSM0 PTHR12341:SF41 5'->3' EXORIBONUCLEASE 5'-3' EXORIBONUCLEASE 2 catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;nuclease activity#GO:0004518;5'-3' exonuclease activity#GO:0008409;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters#GO:0016796;hydrolase activity#GO:0016787;catalytic activity, acting on a nucleic acid#GO:0140640;exonuclease activity#GO:0004527;RNA nuclease activity#GO:0004540 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;heterocycle catabolic process#GO:0046700;RNA metabolic process#GO:0016070;nucleobase-containing compound metabolic process#GO:0006139;cellular nitrogen compound catabolic process#GO:0044270;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;mRNA catabolic process#GO:0006402;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance catabolic process#GO:1901575;negative regulation of cellular process#GO:0048523;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;negative regulation of biosynthetic process#GO:0009890;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;nuclear-transcribed mRNA catabolic process#GO:0000956;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;nucleobase-containing compound catabolic process#GO:0034655;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031;exoribonuclease#PC00099 DNA replication#P00017>5' to 3' Exoribonulcease#P00535 CIOIN|Ensembl=ENSCING00000004522.3|UniProtKB=F7A9W3 F7A9W3 LOC100177142 PTHR46923:SF1 CATION CHANNEL SPERM-ASSOCIATED PROTEIN 2 CATION CHANNEL SPERM-ASSOCIATED PROTEIN 2 sperm capacitation#GO:0048240;germ cell development#GO:0007281;male gamete generation#GO:0048232;cellular developmental process#GO:0048869;fertilization#GO:0009566;gamete generation#GO:0007276;cellular process involved in reproduction in multicellular organism#GO:0022412;multicellular organism reproduction#GO:0032504;developmental process#GO:0032502;microtubule-based movement#GO:0007018;cilium or flagellum-dependent cell motility#GO:0001539;cell motility#GO:0048870;sperm motility#GO:0097722;spermatid differentiation#GO:0048515;cellular process#GO:0009987;cilium movement involved in cell motility#GO:0060294;cilium movement#GO:0003341;cell development#GO:0048468;developmental process involved in reproduction#GO:0003006;cilium-dependent cell motility#GO:0060285;cell differentiation#GO:0030154;spermatid development#GO:0007286;reproduction#GO:0000003;microtubule-based process#GO:0007017;anatomical structure development#GO:0048856;sexual reproduction#GO:0019953;spermatogenesis#GO:0007283;reproductive process#GO:0022414;multicellular organismal process#GO:0032501;flagellated sperm motility#GO:0030317;multicellular organismal reproductive process#GO:0048609 voltage-gated calcium channel complex#GO:0005891;membrane protein complex#GO:0098796;CatSper complex#GO:0036128;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;calcium channel complex#GO:0034704;membrane#GO:0016020;cation channel complex#GO:0034703;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 CIOIN|Ensembl=ENSCING00000006604.3|UniProtKB=A0A8D3ERV2 A0A8D3ERV2 PTHR21266:SF32 IRON-SULFUR DOMAIN CONTAINING PROTEIN CHOLESTEROL 7-DESATURASE NVD oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 oxygenase#PC00177;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000019627.1|UniProtKB=H2XSW5 H2XSW5 LOC100183788 PTHR10671:SF108 EPITHELIAL MEMBRANE PROTEIN-RELATED CLAUDIN FAMILY PROTEIN-RELATED cytoskeletal protein#PC00085 CIOIN|Ensembl=ENSCING00000015136.2|UniProtKB=F6Y6K2 F6Y6K2 LOC100183187 PTHR31598:SF1 IQ DOMAIN-CONTAINING PROTEIN D DYNEIN REGULATORY COMPLEX PROTEIN 10 CIOIN|Ensembl=ENSCING00000022964.1|UniProtKB=H2XUJ7 H2XUJ7 PTHR21686:SF12 DEOXYNUCLEOTIDYLTRANSFERASE TERMINAL-INTERACTING PROTEIN 2 DEOXYNUCLEOTIDYLTRANSFERASE TERMINAL-INTERACTING PROTEIN 2 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000012863.2|UniProtKB=F6Q071 F6Q071 PTHR46600:SF1 THAP DOMAIN-CONTAINING THAP DOMAIN-CONTAINING PROTEIN 1 zinc finger transcription factor#PC00244 CIOIN|Ensembl=ENSCING00000022203.1|UniProtKB=H2XRW4 H2XRW4 PTHR10849:SF20 NADH DEHYDROGENASE UBIQUINONE IRON-SULFUR PROTEIN 8, MITOCHONDRIAL NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 8, MITOCHONDRIAL NADH dehydrogenase activity#GO:0003954;oxidoreductase activity, acting on NAD(P)H#GO:0016651;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 cellular metabolic process#GO:0044237;cellular respiration#GO:0045333;aerobic respiration#GO:0009060;cellular process#GO:0009987;energy derivation by oxidation of organic compounds#GO:0015980;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152 oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000007606.3|UniProtKB=F6ZJP7 F6ZJP7 PTHR45625:SF2 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-RELATED PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-LIKE 3 peptidyl-prolyl cis-trans isomerase activity#GO:0003755;isomerase activity#GO:0016853;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;protein peptidyl-prolyl isomerization#GO:0000413;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 ribonucleoprotein complex#GO:1990904;catalytic step 2 spliceosome#GO:0071013;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622 chaperone#PC00072 CIOIN|Ensembl=ENSCING00000002364.3|UniProtKB=F6RA65 F6RA65 PTHR45852:SF1 SER/THR-PROTEIN KINASE RIO2 SERINE_THREONINE-PROTEIN KINASE RIO2 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;maturation of SSU-rRNA#GO:0030490;ribosomal small subunit biogenesis#GO:0042274;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;preribosome, small subunit precursor#GO:0030688;preribosome#GO:0030684;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000000878.3|UniProtKB=F6UPQ6 F6UPQ6 LOC100187261 PTHR21377:SF0 PROTEIN FAM210B, MITOCHONDRIAL PROTEIN FAM210B, MITOCHONDRIAL cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000003441.3|UniProtKB=F6XKK7 F6XKK7 PTHR11255:SF80 DIACYLGLYCEROL KINASE EYE-SPECIFIC DIACYLGLYCEROL KINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301;lipid kinase activity#GO:0001727 cellular anatomical entity#GO:0110165;membrane#GO:0016020 transferase#PC00220;kinase#PC00137;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000020263.1|UniProtKB=H2XN36 H2XN36 PTHR20883:SF14 PHYTANOYL-COA DIOXYGENASE DOMAIN CONTAINING 1 PHYTANOYL-COA DIOXYGENASE oxygenase#PC00177;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000002129.3|UniProtKB=F6WRF3 F6WRF3 PTHR12746:SF2 NONSENSE-MEDIATED MRNA DECAY PROTEIN 3 60S RIBOSOMAL EXPORT PROTEIN NMD3 ribonucleoprotein complex binding#GO:0043021;ribosome binding#GO:0043022;protein-containing complex binding#GO:0044877;binding#GO:0005488 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000006959.3|UniProtKB=F6UZR9 F6UZR9 PTHR10704:SF71 CARBOHYDRATE SULFOTRANSFERASE CARBOHYDRATE SULFOTRANSFERASE 1-LIKE sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824 cellular metabolic process#GO:0044237;amino sugar metabolic process#GO:0006040;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000007511.3|UniProtKB=F6X709 F6X709 LOC100180562 PTHR31180:SF3 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 107-RELATED EXPRESSED SEQUENCE EH456644 CIOIN|Ensembl=ENSCING00000002458.3|UniProtKB=F6Q8V1 F6Q8V1 PTHR13510:SF44 FYVE-FINGER-CONTAINING RAB5 EFFECTOR PROTEIN RABENOSYN-5-RELATED RABENOSYN-5 CIOIN|Ensembl=ENSCING00000012884.2|UniProtKB=F6PU76 F6PU76 PTHR14898:SF0 ENHANCER OF POLYCOMB ENHANCER OF POLYCOMB-LIKE PROTEIN regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991 chromatin/chromatin-binding, or -regulatory protein#PC00077 CIOIN|Ensembl=ENSCING00000007306.3|UniProtKB=F6Z3T2 F6Z3T2 PTHR12696:SF0 TIP120 CULLIN-ASSOCIATED NEDD8-DISSOCIATED PROTEIN 1 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein-containing complex assembly#GO:0065003;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular component organization#GO:0016043;cellular process#GO:0009987;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nitrogen compound metabolic process#GO:0006807;protein-containing complex organization#GO:0043933;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000013218.2|UniProtKB=F6V5I4 F6V5I4 LOC100183442 PTHR12991:SF10 NITROGEN PERMEASE REGULATOR 2/TUMOR SUPPRESSOR CANDIDATE 4 GATOR COMPLEX PROTEIN NPRL2 nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;regulation of TORC1 signaling#GO:1903432;negative regulation of response to stimulus#GO:0048585;regulation of catabolic process#GO:0009894;negative regulation of intracellular signal transduction#GO:1902532;regulation of autophagy#GO:0010506;positive regulation of cellular metabolic process#GO:0031325;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;positive regulation of cellular catabolic process#GO:0031331;regulation of cellular catabolic process#GO:0031329;regulation of intracellular signal transduction#GO:1902531;negative regulation of TOR signaling#GO:0032007;regulation of TOR signaling#GO:0032006;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of metabolic process#GO:0009893;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of catabolic process#GO:0009896;negative regulation of signal transduction#GO:0009968;positive regulation of autophagy#GO:0010508;negative regulation of TORC1 signaling#GO:1904262;positive regulation of biological process#GO:0048518;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 bounding membrane of organelle#GO:0098588;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;Seh1-associated complex#GO:0035859;intracellular membrane-bounded organelle#GO:0043231;vacuolar membrane#GO:0005774;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 GTPase-activating protein#PC00257 CIOIN|Ensembl=ENSCING00000002930.3|UniProtKB=F6R8M3 F6R8M3 PTHR24026:SF125 FAT ATYPICAL CADHERIN-RELATED FAT-LIKE CADHERIN-RELATED TUMOR SUPPRESSOR HOMOLOG cell adhesion molecule#PC00069;cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 CIOIN|Ensembl=ENSCING00000007574.3|UniProtKB=F7BDF6 F7BDF6 PTHR11037:SF20 TRANSCRIPTION FACTOR CP2 PROTEIN GRAINYHEAD DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218 CIOIN|Ensembl=ENSCING00000010079.3|UniProtKB=F6QCG4 F6QCG4 LOC100182368 PTHR10612:SF34 APOLIPOPROTEIN D APOLIPOPROTEIN D apolipoprotein#PC00052;transfer/carrier protein#PC00219 CIOIN|Ensembl=ENSCING00000004054.3|UniProtKB=F7B7A4 F7B7A4 PTHR11848:SF308 TGF-BETA FAMILY BMP-LIKE PROTEIN UNC-129 molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;cytokine activity#GO:0005125;protein binding#GO:0005515;signaling receptor binding#GO:0005102 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 TGF-beta signaling pathway#P00052>TGFbeta#P01286 CIOIN|Ensembl=ENSCING00000001635.3|UniProtKB=F7API1 F7API1 PTHR24089:SF705 SOLUTE CARRIER FAMILY 25 SOLUTE CARRIER FAMILY 25 MEMBER 16 carbohydrate derivative transmembrane transporter activity#GO:1901505;purine nucleotide transmembrane transporter activity#GO:0015216;nucleobase-containing compound transmembrane transporter activity#GO:0015932;transmembrane transporter activity#GO:0022857;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215 localization#GO:0051179;mitochondrial transport#GO:0006839;organic substance transport#GO:0071702;organophosphate ester transport#GO:0015748;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;organic anion transport#GO:0015711;nucleobase-containing compound transport#GO:0015931;transport#GO:0006810;nitrogen compound transport#GO:0071705;cellular process#GO:0009987;mitochondrial transmembrane transport#GO:1990542;carbohydrate derivative transport#GO:1901264 envelope#GO:0031975;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;organelle membrane#GO:0031090;organelle inner membrane#GO:0019866;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227 mitochondrial carrier protein#PC00158;secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000008039.3|UniProtKB=F6S5C8 F6S5C8 PTHR11849:SF304 ETS DNA-BINDING PROTEIN D-ETS-3 transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 CIOIN|Ensembl=ENSCING00000009633.3|UniProtKB=F6ZU35 F6ZU35 PTHR12413:SF1 DOLICHYL GLYCOSYLTRANSFERASE DOLICHYL PYROPHOSPHATE MAN9GLCNAC2 ALPHA-1,3-GLUCOSYLTRANSFERASE glucosyltransferase activity#GO:0046527;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein N-linked glycosylation#GO:0006487;cellular lipid metabolic process#GO:0044255;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111 CIOIN|Ensembl=ENSCING00000024643.1|UniProtKB=H2XWH8 H2XWH8 PTHR46218:SF4 LASP LIM AND SH3 DOMAIN PROTEIN LASP CIOIN|Ensembl=ENSCING00000002076.3|UniProtKB=F7AAL8 F7AAL8 LOC100181727 PTHR13023:SF3 APYRASE SOLUBLE CALCIUM-ACTIVATED NUCLEOTIDASE 1 pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside diphosphate phosphatase activity#GO:0017110;catalytic activity#GO:0003824 glycoprotein biosynthetic process#GO:0009101;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;proteoglycan metabolic process#GO:0006029;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;proteoglycan biosynthetic process#GO:0030166;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 nucleotide phosphatase#PC00173;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000006223.3|UniProtKB=F6YVW8 F6YVW8 LOC100176808 PTHR45665:SF9 AQUAPORIN-8 AQUAPORIN-8 inorganic molecular entity transmembrane transporter activity#GO:0015318;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;channel activity#GO:0015267;water transmembrane transporter activity#GO:0005372 localization#GO:0051179;water transport#GO:0006833;establishment of localization#GO:0051234;fluid transport#GO:0042044;transport#GO:0006810 cellular anatomical entity#GO:0110165;membrane#GO:0016020 CIOIN|Ensembl=ENSCING00000020871.1|UniProtKB=H2Y0E0 H2Y0E0 LOC100178289 PTHR13826:SF14 INTESTINAL TREFOIL FACTOR-RELATED TREFOIL FACTOR 2 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 CIOIN|Ensembl=ENSCING00000021062.1|UniProtKB=A0A1W2WKU4 A0A1W2WKU4 LOC100185040 PTHR12644:SF0 ARP2/3 COMPLEX 16 KD SUBUNIT P16-ARC ACTIN-RELATED PROTEIN 2_3 COMPLEX SUBUNIT 5 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;Arp2/3 complex-mediated actin nucleation#GO:0034314;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;Arp2/3 protein complex#GO:0005885;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 Integrin signalling pathway#P00034>Arp2/3#P00912;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Arp2/3#P00876;Cytoskeletal regulation by Rho GTPase#P00016>ARP2/3#P00511 CIOIN|Ensembl=ENSCING00000012932.2|UniProtKB=F6RLL0 F6RLL0 PTHR45617:SF165 LEUCINE RICH REPEAT FAMILY PROTEIN COMMON DPR-INTERACTING PROTEIN-RELATED scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000003202.3|UniProtKB=F6S360 F6S360 PTHR43176:SF3 3-HYDROXYISOBUTYRYL-COA HYDROLASE-RELATED 3-HYDROXYISOBUTYRYL-COA HYDROLASE, MITOCHONDRIAL oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 oxoacid metabolic process#GO:0043436;branched-chain amino acid metabolic process#GO:0009081;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;amino acid catabolic process#GO:0009063;small molecule catabolic process#GO:0044282;nitrogen compound metabolic process#GO:0006807;alpha-amino acid metabolic process#GO:1901605;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;carboxylic acid metabolic process#GO:0019752;amino acid metabolic process#GO:0006520;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000017654.2|UniProtKB=F6WZ22 F6WZ22 LOC101243466 PTHR46513:SF13 VITELLOGENIN RECEPTOR-LIKE PROTEIN-RELATED-RELATED EGF-LIKE DOMAIN-CONTAINING PROTEIN transmembrane signal receptor#PC00197 CIOIN|Ensembl=ENSCING00000009634.3|UniProtKB=F7BEI8 F7BEI8 LOC100187286 PTHR32083:SF0 CILIA AND FLAGELLA-ASSOCIATED PROTEIN 58-RELATED CILIA AND FLAGELLA-ASSOCIATED PROTEIN 58 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 structural protein#PC00211 CIOIN|Ensembl=ENSCING00000004689.3|UniProtKB=F6QNM6 F6QNM6 PTHR10663:SF342 GUANYL-NUCLEOTIDE EXCHANGE FACTOR FI21420P1 cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actin filament-based process#GO:0030029;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987;organelle organization#GO:0006996 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 CIOIN|Ensembl=ENSCING00000004958.3|UniProtKB=F6X9L5 F6X9L5 LOC100179675 PTHR42690:SF1 THREONINE SYNTHASE FAMILY MEMBER THREONINE SYNTHASE-LIKE 2 Vitamin B6 metabolism#P02787>Threonine synthase#P03242;Threonine biosynthesis#P02781>Threonine synthase#P03190 CIOIN|Ensembl=ENSCING00000002349.3|UniProtKB=A0A1W2W3E0 A0A1W2W3E0 LOC100185771 PTHR19269:SF45 TROPOMYOSIN TROPOMYOSIN-1, ISOFORMS 33_34 cytoskeletal protein#PC00085;actin binding motor protein#PC00040 CIOIN|Ensembl=ENSCING00000001205.3|UniProtKB=F6TKL9 F6TKL9 LOC100180551 PTHR20854:SF4 INOSITOL MONOPHOSPHATASE INOSITOL-1-MONOPHOSPHATASE-RELATED inositol phosphate phosphatase activity#GO:0052745;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 regulation of biological process#GO:0050789;organic hydroxy compound metabolic process#GO:1901615;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;alcohol metabolic process#GO:0006066;cellular process#GO:0009987;signaling#GO:0023052;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704 phosphatase#PC00181;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000023049.1|UniProtKB=F6UJX7 F6UJX7 LOC100179852 PTHR19143:SF458 FIBRINOGEN/TENASCIN/ANGIOPOEITIN FIBRINOGEN C-TERMINAL DOMAIN-CONTAINING PROTEIN-RELATED external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 CIOIN|Ensembl=ENSCING00000014087.2|UniProtKB=F6TE72 F6TE72 PTHR11584:SF394 SERINE/THREONINE PROTEIN KINASE APOPTOTIC SIGNAL-REGULATING KINASE 1, ISOFORM C transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;kinase activity#GO:0016301;protein kinase activity#GO:0004672 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 FGF signaling pathway#P00021>MEKK1-5#P00634;EGF receptor signaling pathway#P00018>MEKK1-5#P00553 CIOIN|Ensembl=ENSCING00000003247.3|UniProtKB=F6Z5D4 F6Z5D4 PTHR14907:SF2 FI14130P SUPPRESSOR APC DOMAIN-CONTAINING PROTEIN 2 CIOIN|Ensembl=ENSCING00000016822.2|UniProtKB=F6QD16 F6QD16 PTHR31395:SF25 SHISA ABLIM_ANCHOR DOMAIN-CONTAINING PROTEIN scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000003236.3|UniProtKB=A0A1W2WHI2 A0A1W2WHI2 LOC100184910 PTHR46380:SF2 CYCLIN-D-BINDING MYB-LIKE TRANSCRIPTION FACTOR 1 CYCLIN-D-BINDING MYB-LIKE TRANSCRIPTION FACTOR 1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 CIOIN|Ensembl=ENSCING00000010712.3|UniProtKB=Q4H2M1 Q4H2M1 Ci-xBPb PTHR46542:SF1 X-BOX BINDING PROTEIN 1 X-BOX BINDING PROTEIN 1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000009159.3|UniProtKB=F6ZNP4 F6ZNP4 LOC100179695 PTHR11709:SF518 MULTI-COPPER OXIDASE MULTICOPPER OXIDASE oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 oxidase#PC00175;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000007345.3|UniProtKB=F6XYB7 F6XYB7 LOC100181090 PTHR22809:SF5 METHYLTRANSFERASE-RELATED TRNA N(3)-METHYLCYTIDINE METHYLTRANSFERASE METTL6 methyltransferase#PC00155 CIOIN|Ensembl=ENSCING00000013361.2|UniProtKB=F6YWM5 F6YWM5 PTHR19290:SF162 BASIC HELIX-LOOP-HELIX PROTEIN NEUROGENIN-RELATED TRANSCRIPTION FACTOR ATOH7 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of nitrogen compound metabolic process#GO:0051173;neurogenesis#GO:0022008;positive regulation of RNA biosynthetic process#GO:1902680;cell projection organization#GO:0030030;regulation of nitrogen compound metabolic process#GO:0051171;animal organ development#GO:0048513;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;neuron differentiation#GO:0030182;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;multicellular organism development#GO:0007275;cellular component organization#GO:0016043;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;anatomical structure development#GO:0048856;biological regulation#GO:0065007;neuron development#GO:0048666;multicellular organismal process#GO:0032501;positive regulation of RNA metabolic process#GO:0051254;generation of neurons#GO:0048699;sensory organ development#GO:0007423;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;basic helix-loop-helix transcription factor#PC00055 CIOIN|Ensembl=ENSCING00000008922.3|UniProtKB=F6QAL4 F6QAL4 LOC100177966 PTHR43735:SF3 APOPTOSIS-INDUCING FACTOR 1 FERROPTOSIS SUPPRESSOR PROTEIN 1 nucleotide binding#GO:0000166;electron transfer activity#GO:0009055;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;flavin adenine dinucleotide binding#GO:0050660;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167;oxidoreductase activity#GO:0016491 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 p53 pathway#P00059>NOXA#G01572 CIOIN|Ensembl=ENSCING00000002333.3|UniProtKB=F6PNP3 F6PNP3 PTHR28358:SF1 TRANSMEMBRANE PROTEIN 127 TRANSMEMBRANE PROTEIN 127 regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;regulation of signaling#GO:0023051;biological regulation#GO:0065007;regulation of intracellular signal transduction#GO:1902531;regulation of TOR signaling#GO:0032006 cellular anatomical entity#GO:0110165;membrane#GO:0016020 CIOIN|Ensembl=ENSCING00000005605.3|UniProtKB=H2XSN3 H2XSN3 PTHR42738:SF7 HYDROXYMETHYLGLUTARYL-COA LYASE HYDROXYMETHYLGLUTARYL-COA LYASE lyase activity#GO:0016829;carbon-carbon lyase activity#GO:0016830;catalytic activity#GO:0003824 oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;branched-chain amino acid metabolic process#GO:0009081;generation of precursor metabolites and energy#GO:0006091;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;amino acid catabolic process#GO:0009063;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;nitrogen compound metabolic process#GO:0006807;alpha-amino acid metabolic process#GO:1901605;catabolic process#GO:0009056;small molecule biosynthetic process#GO:0044283;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;carboxylic acid metabolic process#GO:0019752;amino acid metabolic process#GO:0006520;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 lyase#PC00144 CIOIN|Ensembl=ENSCING00000023549.1|UniProtKB=H2XJS0 H2XJS0 PTHR11689:SF89 CHLORIDE CHANNEL PROTEIN CLC FAMILY MEMBER CHLORIDE CHANNEL PROTEIN inorganic molecular entity transmembrane transporter activity#GO:0015318;transmembrane transporter activity#GO:0022857;chloride transmembrane transporter activity#GO:0015108;monoatomic anion transmembrane transporter activity#GO:0008509;inorganic anion transmembrane transporter activity#GO:0015103;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ion channel#PC00133;transporter#PC00227 CIOIN|Ensembl=ENSCING00000019179.1|UniProtKB=H2Y257 H2Y257 PTHR24372:SF77 GLYCOPROTEIN HORMONE RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 response to organic substance#GO:0010033;positive regulation of adenylate cyclase activity#GO:0045762;regulation of lyase activity#GO:0051339;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;cellular response to stimulus#GO:0051716;regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;cellular response to endogenous stimulus#GO:0071495;cellular response to chemical stimulus#GO:0070887;positive regulation of catalytic activity#GO:0043085;cellular response to organic substance#GO:0071310;regulation of cyclase activity#GO:0031279;positive regulation of molecular function#GO:0044093;cell communication#GO:0007154;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;positive regulation of cyclase activity#GO:0031281;hormone-mediated signaling pathway#GO:0009755;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to endogenous stimulus#GO:0009719;response to hormone#GO:0009725;cellular response to hormone stimulus#GO:0032870;response to chemical#GO:0042221;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of lyase activity#GO:0051349;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 CIOIN|Ensembl=ENSCING00000024978.1|UniProtKB=H2XRT4 H2XRT4 LOC100182046 PTHR24543:SF325 MULTICOPPER OXIDASE-RELATED F5_8 TYPE C DOMAIN-CONTAINING PROTEIN oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000009005.3|UniProtKB=F6PHJ3 F6PHJ3 PTHR10529:SF344 AP COMPLEX SUBUNIT MU PROTEIN STONED-B molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 cellular localization#GO:0051641;regulation of endocytosis#GO:0030100;synaptic vesicle cycle#GO:0099504;synaptic vesicle endocytosis#GO:0048488;clathrin-dependent endocytosis#GO:0072583;endocytosis#GO:0006897;transport#GO:0006810;vesicle-mediated transport#GO:0016192;regulation of localization#GO:0032879;regulation of cellular component organization#GO:0051128;cellular process#GO:0009987;regulation of vesicle-mediated transport#GO:0060627;localization#GO:0051179;regulation of biological process#GO:0050789;synaptic vesicle recycling#GO:0036465;regulation of transport#GO:0051049;establishment of localization#GO:0051234;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;receptor-mediated endocytosis#GO:0006898;import into cell#GO:0098657;vesicle-mediated transport in synapse#GO:0099003 bounding membrane of organelle#GO:0098588;synapse#GO:0045202;intracellular membrane-bounded organelle#GO:0043231;synaptic vesicle#GO:0008021;plasma membrane protein complex#GO:0098797;clathrin vesicle coat#GO:0030125;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;AP-type membrane coat adaptor complex#GO:0030119;clathrin-coated vesicle#GO:0030136;membrane coat#GO:0030117;coated membrane#GO:0048475;cytoplasmic vesicle membrane#GO:0030659;clathrin-coated pit#GO:0005905;membrane protein complex#GO:0098796;presynapse#GO:0098793;intracellular vesicle#GO:0097708;cell junction#GO:0030054;cell periphery#GO:0071944;membrane#GO:0016020;coated vesicle#GO:0030135;vesicle coat#GO:0030120;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;coated vesicle membrane#GO:0030662;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;transport vesicle#GO:0030133;endocytic vesicle#GO:0030139;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 membrane traffic protein#PC00150 CIOIN|Ensembl=ENSCING00000021648.1|UniProtKB=H2XSC4 H2XSC4 PTHR22802:SF379 C-TYPE LECTIN SUPERFAMILY MEMBER CHONDROITIN SULFATE PROTEOGLYCAN 2 ISOFORM X1 membrane traffic protein#PC00150 CIOIN|Ensembl=ENSCING00000019104.1|UniProtKB=H2XLP2 H2XLP2 PTHR21255:SF65 T-COMPLEX-ASSOCIATED-TESTIS-EXPRESSED 1/ DYNEIN LIGHT CHAIN TCTEX1 DOMAIN-CONTAINING PROTEIN 2 protein binding#GO:0005515;binding#GO:0005488 microtubule-based movement#GO:0007018;cellular process#GO:0009987;microtubule-based process#GO:0007017 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;microtubule cytoskeleton#GO:0015630;dynein complex#GO:0030286;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic dynein complex#GO:0005868;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;microtubule or microtubule-binding cytoskeletal protein#PC00157 CIOIN|Ensembl=ENSCING00000003952.3|UniProtKB=F6ZLL7 F6ZLL7 PTHR12843:SF5 PROTEIN-LYSINE N-METHYLTRANSFERASE METTL10 EEF1A LYSINE METHYLTRANSFERASE 2 protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000018492.1|UniProtKB=H2XYW1 H2XYW1 PTHR14614:SF164 HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN HISTONE-ARGININE METHYLTRANSFERASE METTL23 protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000013237.2|UniProtKB=F6UFU1 F6UFU1 PTHR24096:SF149 LONG-CHAIN-FATTY-ACID--COA LIGASE AMP-BINDING DOMAIN-CONTAINING PROTEIN-RELATED ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877 metabolite interconversion enzyme#PC00262;ligase#PC00142 CIOIN|Ensembl=ENSCING00000005673.3|UniProtKB=F6YY15 F6YY15 PTHR10150:SF0 DNA REPAIR ENDONUCLEASE XPF DNA REPAIR ENDONUCLEASE XPF hydrolase activity, acting on ester bonds#GO:0016788;DNA endonuclease activity#GO:0004520;nucleic acid binding#GO:0003676;nuclease activity#GO:0004518;single-stranded DNA binding#GO:0003697;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;endonuclease activity#GO:0004519;damaged DNA binding#GO:0003684;hydrolase activity#GO:0016787;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on DNA#GO:0140097;DNA nuclease activity#GO:0004536 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;double-strand break repair#GO:0006302;nuclear division#GO:0000280;cell cycle process#GO:0022402;nucleobase-containing compound metabolic process#GO:0006139;reciprocal homologous recombination#GO:0140527;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;interstrand cross-link repair#GO:0036297;nitrogen compound metabolic process#GO:0006807;meiotic cell cycle process#GO:1903046;recombinational repair#GO:0000725;meiosis I cell cycle process#GO:0061982;reciprocal meiotic recombination#GO:0007131;reproductive process#GO:0022414;meiosis I#GO:0007127;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleotide-excision repair#GO:0006289;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;meiotic cell cycle#GO:0051321;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;double-strand break repair via homologous recombination#GO:0000724;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;resolution of meiotic recombination intermediates#GO:0000712;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;reproduction#GO:0000003;organelle organization#GO:0006996;meiotic nuclear division#GO:0140013;sexual reproduction#GO:0019953;cell cycle#GO:0007049;organelle fission#GO:0048285;homologous recombination#GO:0035825;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleotide-excision repair complex#GO:0000109;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 endodeoxyribonuclease#PC00093 CIOIN|Ensembl=ENSCING00000006175.3|UniProtKB=F7BKG7 F7BKG7 LOC100182700 PTHR23044:SF61 3'-5' EXONUCLEASE ERI1-RELATED 3'-5' EXORIBONUCLEASE 1-RELATED RNA metabolism protein#PC00031;exoribonuclease#PC00099 CIOIN|Ensembl=ENSCING00000014790.1|UniProtKB=F6VLF4 F6VLF4 LOC100184687 PTHR46355:SF1 UPF0428 PROTEIN CXORF56 STING ER EXIT PROTEIN endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;endoplasmic reticulum organization#GO:0007029;membrane organization#GO:0061024;transport#GO:0006810;endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;organelle organization#GO:0006996;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 CIOIN|Ensembl=ENSCING00000013424.1|UniProtKB=F6V3E7 F6V3E7 PTHR13954:SF6 IRE1-RELATED NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE tyrosine protein kinase receptor#PC00233 Alzheimer disease-presenilin pathway#P00004>Ire-1#P00144;Alzheimer disease-presenilin pathway#P00004>Ire-1 N-terminal fragment#P00110;Alzheimer disease-presenilin pathway#P00004>Ire-1 C-terminal fragment#P00125 CIOIN|Ensembl=ENSCING00000024087.1|UniProtKB=H2XJZ3 H2XJZ3 PTHR24039:SF52 FIBRILLIN-RELATED EGF-LIKE DOMAIN-CONTAINING PROTEIN extracellular matrix structural protein#PC00103 CIOIN|Ensembl=ENSCING00000006930.3|UniProtKB=F6VPC4 F6VPC4 PTHR24391:SF27 HISTONE H4 TRANSCRIPTION FACTOR-RELATED ZINC FINGER PROTEIN 1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 CIOIN|Ensembl=ENSCING00000019802.1|UniProtKB=H2XMV3 H2XMV3 PTHR19143:SF379 FIBRINOGEN/TENASCIN/ANGIOPOEITIN FIBROLEUKIN-LIKE external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 CIOIN|Ensembl=ENSCING00000018102.1|UniProtKB=H2XMG9 H2XMG9 LOC100180805 PTHR10671:SF108 EPITHELIAL MEMBRANE PROTEIN-RELATED CLAUDIN FAMILY PROTEIN-RELATED cytoskeletal protein#PC00085 CIOIN|Ensembl=ENSCING00000007255.3|UniProtKB=A0A1W5BDY9 A0A1W5BDY9 LOC100181638 PTHR47990:SF34 2-OXOGLUTARATE (2OG) AND FE(II)-DEPENDENT OXYGENASE SUPERFAMILY PROTEIN-RELATED IRON_ASCORBATE OXIDOREDUCTASE DDB_G0283291-RELATED 2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;dioxygenase activity#GO:0051213 oxygenase#PC00177;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000006984.3|UniProtKB=F6SY80 F6SY80 PTHR46021:SF2 ARF-GAP WITH DUAL PH DOMAIN-CONTAINING PROTEIN 1-LIKE PROTEIN ARF-GAP WITH DUAL PH DOMAIN-CONTAINING PROTEIN 1 nucleoside-triphosphatase regulator activity#GO:0060589;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;small molecule binding#GO:0036094;binding#GO:0005488;molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047;lipid binding#GO:0008289;anion binding#GO:0043168;phosphatidylinositol binding#GO:0035091;ion binding#GO:0043167;phospholipid binding#GO:0005543;phosphatidylinositol phosphate binding#GO:1901981;enzyme regulator activity#GO:0030234 biological regulation#GO:0065007;regulation of hydrolase activity#GO:0051336;regulation of catalytic activity#GO:0050790;regulation of GTPase activity#GO:0043087;regulation of molecular function#GO:0065009 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 CIOIN|Ensembl=ENSCING00000004654.3|UniProtKB=Q9NL28 Q9NL28 Ci-NET1a PTHR10574:SF365 NETRIN/LAMININ-RELATED NETRIN-A-RELATED neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;cell projection organization#GO:0030030;animal organ development#GO:0048513;developmental process#GO:0032502;dendrite development#GO:0016358;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cellular anatomical entity morphogenesis#GO:0032989;system development#GO:0048731;cell differentiation#GO:0030154;axon guidance#GO:0007411;anatomical structure morphogenesis#GO:0009653;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;axonogenesis#GO:0007409;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;cellular component organization#GO:0016043;cell morphogenesis#GO:0000902;cellular process#GO:0009987;tissue development#GO:0009888;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;cell morphogenesis involved in neuron differentiation#GO:0048667;motor neuron axon guidance#GO:0008045;anatomical structure development#GO:0048856;animal organ morphogenesis#GO:0009887;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;basement membrane#GO:0005604 extracellular matrix protein#PC00102 Axon guidance mediated by netrin#P00009>Netrin#P00357;Axon guidance mediated by Slit/Robo#P00008>Netrin#P00344 CIOIN|Ensembl=ENSCING00000013509.2|UniProtKB=L7N0U8 L7N0U8 PTHR47456:SF6 PHD-TYPE DOMAIN-CONTAINING PROTEIN SI:DKEY-31C13.1 CIOIN|Ensembl=ENSCING00000012369.2|UniProtKB=F6WM93 F6WM93 PTHR11819:SF196 SOLUTE CARRIER FAMILY 5 SODIUM_GLUCOSE COTRANSPORTER 4 inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;carbohydrate transmembrane transporter activity#GO:0015144;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;sugar transmembrane transporter activity#GO:0051119;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;active transmembrane transporter activity#GO:0022804;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;active monoatomic ion transmembrane transporter activity#GO:0022853;monoatomic ion transmembrane transporter activity#GO:0015075;inorganic cation transmembrane transporter activity#GO:0022890;solute:monoatomic cation symporter activity#GO:0015294 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000014879.2|UniProtKB=F6ZA28 F6ZA28 PTHR31302:SF0 TRANSMEMBRANE PROTEIN WITH METALLOPHOSPHOESTERASE DOMAIN-RELATED TRANSMEMBRANE PROTEIN WITH METALLOPHOSPHOESTERASE DOMAIN CIOIN|Ensembl=ENSCING00000008436.3|UniProtKB=F6UF46 F6UF46 PTHR47330:SF1 POLY(U)-BINDING-SPLICING FACTOR PUF60-B-RELATED POLY(U)-BINDING-SPLICING FACTOR PUF60 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;RNA processing#GO:0006396;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;protein-RNA complex assembly#GO:0022618;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;alternative mRNA splicing, via spliceosome#GO:0000380;regulation of mRNA processing#GO:0050684;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular component organization#GO:0016043;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;mRNA splice site recognition#GO:0006376;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;regulation of RNA splicing#GO:0043484;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;protein-containing complex organization#GO:0043933;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;ribonucleoprotein complex biogenesis#GO:0022613;biological regulation#GO:0065007;mRNA processing#GO:0006397;protein-RNA complex organization#GO:0071826;RNA splicing, via transesterification reactions#GO:0000375;spliceosomal complex assembly#GO:0000245;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;regulation of metabolic process#GO:0019222;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323 ribonucleoprotein complex#GO:1990904;catalytic step 2 spliceosome#GO:0071013;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;precatalytic spliceosome#GO:0071011;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622 RNA splicing factor#PC00148;RNA processing factor#PC00147 CIOIN|Ensembl=ENSCING00000002002.3|UniProtKB=F6WTB4 F6WTB4 PTHR15592:SF27 MATRIN 3/NUCLEAR PROTEIN 220-RELATED HEPHAESTUS, ISOFORM Y nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nitrogen compound metabolic process#GO:0051171;regulation of biosynthetic process#GO:0009889;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA metabolic process#GO:0051252;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA processing factor#PC00147;RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000022645.1|UniProtKB=H2XQE9 H2XQE9 PTHR11214:SF283 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE N-ACETYLLACTOSAMINIDE BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE 4-LIKE transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;protein O-linked glycosylation#GO:0006493;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 bounding membrane of organelle#GO:0098588;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;Golgi membrane#GO:0000139;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111 CIOIN|Ensembl=ENSCING00000023197.1|UniProtKB=F6YHB0 F6YHB0 PTHR23070:SF110 BCS1 AAA-TYPE ATPASE MITOCHONDRIAL CHAPERONE BCS1 CIOIN|Ensembl=ENSCING00000003219.3|UniProtKB=F6S2G5 F6S2G5 PTHR12509:SF9 SPERMATOGENESIS-ASSOCIATED 4-RELATED SPERM FLAGELLAR PROTEIN 1 ISOFORM X1 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 biological regulation#GO:0065007;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of organelle organization#GO:0033043 axoneme#GO:0005930;cytoplasmic region#GO:0099568;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;plasma membrane bounded cell projection cytoplasm#GO:0032838;ciliary plasm#GO:0097014;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cytoskeleton#GO:0005856;cilium#GO:0005929 CIOIN|Ensembl=ENSCING00000005591.3|UniProtKB=H2XMI3 H2XMI3 LOC100181360 PTHR11384:SF59 ATP-BINDING CASSETTE, SUB-FAMILY D MEMBER LYSOSOMAL COBALAMIN TRANSPORTER ABCD4 ATP-binding cassette (ABC) transporter#PC00003;transporter#PC00227 CIOIN|Ensembl=ENSCING00000009652.3|UniProtKB=F6WV80 F6WV80 PTHR48012:SF2 STERILE20-LIKE KINASE, ISOFORM B-RELATED STERILE20-LIKE KINASE, ISOFORM B transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;phosphorylation#GO:0016310;protein phosphorylation#GO:0006468;cellular process#GO:0009987;protein metabolic process#GO:0019538;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000004555.3|UniProtKB=F6ZQG8 F6ZQG8 LOC100187265 PTHR15154:SF2 HAMARTIN HAMARTIN regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;negative regulation of response to stimulus#GO:0048585;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;negative regulation of TOR signaling#GO:0032007;regulation of intracellular signal transduction#GO:1902531;regulation of TOR signaling#GO:0032006;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;regulation of cell cycle#GO:0051726;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622 Insulin/IGF pathway-protein kinase B signaling cascade#P00033>TSC1#P04495;p53 pathway by glucose deprivation#P04397>TSC1#P04645 CIOIN|Ensembl=ENSCING00000006724.3|UniProtKB=F6YLI3 F6YLI3 PTHR19443:SF16 HEXOKINASE HEXOKINASE TYPE 1-RELATED transferase activity, transferring phosphorus-containing groups#GO:0016772;carbohydrate kinase activity#GO:0019200;transferase activity#GO:0016740;hexokinase activity#GO:0004396;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301 monosaccharide metabolic process#GO:0005996;carbohydrate phosphorylation#GO:0046835;cellular metabolic process#GO:0044237;phosphorylation#GO:0016310;hexose metabolic process#GO:0019318;cellular process#GO:0009987;carbohydrate metabolic process#GO:0005975;glucose metabolic process#GO:0006006;phosphorus metabolic process#GO:0006793;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704 kinase#PC00137 Pentose phosphate pathway#P02762>Hexokinase#P03079;Glycolysis#P00024>Hexokinase#P00677;Fructose galactose metabolism#P02744>Hexokinase#P02966 CIOIN|Ensembl=ENSCING00000012898.2|UniProtKB=F6PT97 F6PT97 LOC100183524 PTHR31728:SF5 ABRAXAS FAMILY MEMBER OS07G0540200 PROTEIN protein binding#GO:0005515;binding#GO:0005488;polyubiquitin modification-dependent protein binding#GO:0031593;modification-dependent protein binding#GO:0140030 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000023776.1|UniProtKB=F6XQI0 F6XQI0 LOC100180954 PTHR11767:SF111 INWARD RECTIFIER POTASSIUM CHANNEL INWARD RECTIFIER POTASSIUM CHANNEL 2-LIKE monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated potassium channel activity#GO:0005249;channel activity#GO:0015267;transporter activity#GO:0005215;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;ligand-gated monoatomic cation channel activity#GO:0099094;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;ligand-gated channel activity#GO:0022834 regulation of monoatomic ion transmembrane transport#GO:0034765;regulation of transmembrane transport#GO:0034762;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;regulation of localization#GO:0032879;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;localization#GO:0051179;regulation of biological process#GO:0050789;import across plasma membrane#GO:0098739;regulation of transport#GO:0051049;establishment of localization#GO:0051234;regulation of cellular process#GO:0050794;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;monoatomic cation transport#GO:0006812;regulation of monoatomic ion transport#GO:0043269;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;import into cell#GO:0098657;potassium ion transport#GO:0006813;potassium ion import across plasma membrane#GO:1990573 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 CIOIN|Ensembl=ENSCING00000002850.3|UniProtKB=F6T0F1 F6T0F1 PTHR45728:SF3 ACETYL-COA CARBOXYLASE, ISOFORM A ACETYL-COA CARBOXYLASE ligase activity#GO:0016874;catalytic activity#GO:0003824 organic acid biosynthetic process#GO:0016053;lipid metabolic process#GO:0006629;oxoacid metabolic process#GO:0043436;monocarboxylic acid biosynthetic process#GO:0072330;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;fatty acid metabolic process#GO:0006631;small molecule biosynthetic process#GO:0044283;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;fatty acid biosynthetic process#GO:0006633;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 CIOIN|Ensembl=ENSCING00000025030.1|UniProtKB=H2Y050 H2Y050 PTHR22939:SF129 SERINE PROTEASE FAMILY S1C HTRA-RELATED SERINE PROTEASE HTRA2, MITOCHONDRIAL serine protease#PC00203;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000008375.3|UniProtKB=F7A1F6 F7A1F6 PTHR10127:SF856 DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING METALLOENDOPEPTIDASE hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000000568.3|UniProtKB=F6SJ11 F6SJ11 PTHR22906:SF49 PROPERDIN COADHESIN-LIKE CIOIN|Ensembl=ENSCING00000008646.3|UniProtKB=F6ZYT4 F6ZYT4 LOC100177323 PTHR42999:SF1 ANTIBIOTIC RESISTANCE PROTEIN MCBG PENTAPEPTIDE REPEAT-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000024750.1|UniProtKB=H2XTR2 H2XTR2 LOC100186306 PTHR23153:SF38 UBX-RELATED UBX DOMAIN-CONTAINING PROTEIN 6 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000002003.3|UniProtKB=F6WT98 F6WT98 PTHR10373:SF38 TRANSCRIPTION FACTOR 7 FAMILY MEMBER PROTEIN PANGOLIN, ISOFORM J sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;cell communication#GO:0007154;cell-cell signaling by wnt#GO:0198738;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;cell-cell signaling#GO:0007267;signaling#GO:0023052;canonical Wnt signaling pathway#GO:0060070;regulation of metabolic process#GO:0019222;Wnt signaling pathway#GO:0016055;regulation of cellular metabolic process#GO:0031323 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 DNA-binding transcription factor#PC00218 CIOIN|Ensembl=ENSCING00000012953.3|UniProtKB=F6RG39 F6RG39 PTHR21539:SF0 SAGA-ASSOCIATED FACTOR 29 SAGA-ASSOCIATED FACTOR 29 protein binding#GO:0005515;methylated histone binding#GO:0035064;binding#GO:0005488;histone binding#GO:0042393;modification-dependent protein binding#GO:0140030 SAGA-type complex#GO:0070461;peptidase complex#GO:1905368;histone acetyltransferase complex#GO:0000123;acetyltransferase complex#GO:1902493;protein-DNA complex#GO:0032993;chromatin#GO:0000785;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein acetyltransferase complex#GO:0031248;protein-containing complex#GO:0032991;chromosome#GO:0005694;SAGA complex#GO:0000124 CIOIN|Ensembl=ENSCING00000019600.1|UniProtKB=H2XXT6 H2XXT6 PTHR19444:SF13 UNC-93 RELATED PROTEIN UNC-93 HOMOLOG A membrane-bound signaling molecule#PC00152 CIOIN|Ensembl=ENSCING00000002742.3|UniProtKB=F6T2M3 F6T2M3 thbsb PTHR10199:SF100 THROMBOSPONDIN THROMBOSPONDIN, ISOFORM A external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165 cell adhesion molecule#PC00069 CIOIN|Ensembl=ENSCING00000006035.3|UniProtKB=F7BMB7 F7BMB7 LOC100178943 PTHR22981:SF7 3-HYDROXYISOBUTYRATE DEHYDROGENASE-RELATED 3-HYDROXYISOBUTYRATE DEHYDROGENASE, MITOCHONDRIAL oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 dehydrogenase#PC00092;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000017333.1|UniProtKB=F6Z4M7 F6Z4M7 PTHR22802:SF379 C-TYPE LECTIN SUPERFAMILY MEMBER CHONDROITIN SULFATE PROTEOGLYCAN 2 ISOFORM X1 membrane traffic protein#PC00150 CIOIN|Ensembl=ENSCING00000004337.3|UniProtKB=F7BML6 F7BML6 PTHR12442:SF22 DYNEIN INTERMEDIATE CHAIN CYTOPLASMIC DYNEIN 1 INTERMEDIATE CHAIN-RELATED protein binding#GO:0005515;binding#GO:0005488 localization#GO:0051179;cellular localization#GO:0051641;microtubule-based transport#GO:0099111;establishment of localization#GO:0051234;microtubule-based process#GO:0007017;transport#GO:0006810;cytoskeleton-dependent intracellular transport#GO:0030705;microtubule-based movement#GO:0007018;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;cellular process#GO:0009987;transport along microtubule#GO:0010970 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;microtubule cytoskeleton#GO:0015630;dynein complex#GO:0030286;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic dynein complex#GO:0005868;intracellular anatomical structure#GO:0005622 microtubule or microtubule-binding cytoskeletal protein#PC00157 Huntington disease#P00029>Dynein complex#P00774 CIOIN|Ensembl=ENSCING00000013501.2|UniProtKB=F7B1U4 F7B1U4 PTHR18870:SF9 PROTEIN TAG-278-RELATED PROTEIN TAG-278-RELATED CIOIN|Ensembl=ENSCING00000014359.2|UniProtKB=F7AZK0 F7AZK0 LOC100177359 PTHR14002:SF54 ENDOGLIN/TGF-BETA RECEPTOR TYPE III ZONA PELLUCIDA SPERM-BINDING PROTEIN 2 transmembrane signal receptor#PC00197 CIOIN|Ensembl=ENSCING00000023413.1|UniProtKB=H2XQC4 H2XQC4 PTHR13132:SF29 ALPHA- 1,6 -FUCOSYLTRANSFERASE ALPHA-(1,6)-FUCOSYLTRANSFERASE transferase activity#GO:0016740;fucosyltransferase activity#GO:0008417;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein glycosylation#GO:0006486;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein N-linked glycosylation#GO:0006487;protein metabolic process#GO:0019538;glycosylation#GO:0070085;glycoprotein metabolic process#GO:0009100;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 glycosyltransferase#PC00111 Notch signaling pathway#P00045>Neurotic#P01115 CIOIN|Ensembl=ENSCING00000023312.1|UniProtKB=H2XUT9 H2XUT9 LOC100182647 PTHR47507:SF6 BARRIER TO AUTOINTEGRATION FACTOR 2 BARRIER-TO-AUTOINTEGRATION FACTOR nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;cellular process#GO:0009987;organelle organization#GO:0006996;chromosome organization#GO:0051276 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;condensed chromosome#GO:0000793;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000006589.3|UniProtKB=L7N0S9 L7N0S9 PTHR42790:SF23 AMINOTRANSFERASE AROMATIC AMINO ACID AMINOTRANSFERASE DDB_G0272014 transaminase activity#GO:0008483;transferase activity#GO:0016740;catalytic activity#GO:0003824 oxoacid metabolic process#GO:0043436;nitrogen compound metabolic process#GO:0006807;alpha-amino acid metabolic process#GO:1901605;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;carboxylic acid metabolic process#GO:0019752;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 transaminase#PC00216 CIOIN|Ensembl=ENSCING00000009028.3|UniProtKB=F6R7R7 F6R7R7 PTHR11937:SF390 ACTIN ACTIN-LIKE ISOFORM X1 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 actin and actin related protein#PC00039;cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 CIOIN|Ensembl=ENSCING00000015440.2|UniProtKB=F6X6U3 F6X6U3 LOC100186966 PTHR11571:SF224 GLUTATHIONE S-TRANSFERASE HEMATOPOIETIC PROSTAGLANDIN D SYNTHASE glutathione transferase activity#GO:0004364;transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824 sulfur compound metabolic process#GO:0006790;nitrogen compound metabolic process#GO:0006807;peptide metabolic process#GO:0006518;cellular modified amino acid metabolic process#GO:0006575;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular process#GO:0009987;glutathione metabolic process#GO:0006749;amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000003772.3|UniProtKB=F7AVB6 F7AVB6 PTHR42737:SF2 GLUTATHIONE REDUCTASE GLUTATHIONE REDUCTASE nucleotide binding#GO:0000166;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;antioxidant activity#GO:0016209;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;flavin adenine dinucleotide binding#GO:0050660;heterocyclic compound binding#GO:1901363;disulfide oxidoreductase activity#GO:0015036;anion binding#GO:0043168;ion binding#GO:0043167;oxidoreductase activity#GO:0016491 cellular response to stimulus#GO:0051716;sulfur compound metabolic process#GO:0006790;cellular response to chemical stimulus#GO:0070887;peptide metabolic process#GO:0006518;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;homeostatic process#GO:0042592;response to oxidative stress#GO:0006979;cellular homeostasis#GO:0019725;cellular process#GO:0009987;glutathione metabolic process#GO:0006749;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;nitrogen compound metabolic process#GO:0006807;cellular modified amino acid metabolic process#GO:0006575;cellular response to oxidative stress#GO:0034599;cellular response to stress#GO:0033554;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 reductase#PC00198;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000021665.1|UniProtKB=H2XVF4 H2XVF4 PTHR11467:SF36 HISTONE H1 HISTONE 24-RELATED nucleosome binding#GO:0031491;nucleic acid binding#GO:0003676;chromatin DNA binding#GO:0031490;binding#GO:0005488;organic cyclic compound binding#GO:0097159;chromatin binding#GO:0003682;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;protein-containing complex binding#GO:0044877 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA metabolic process#GO:0051052;chromosome condensation#GO:0030261;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;cellular process#GO:0009987;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA recombination#GO:0045910;negative regulation of DNA metabolic process#GO:0051053;regulation of DNA recombination#GO:0000018;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 CIOIN|Ensembl=ENSCING00000012183.2|UniProtKB=F6TUG7 F6TUG7 LOC100178719 PTHR15083:SF0 NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 6 NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 6 mitochondrial ATP synthesis coupled electron transport#GO:0042775;aerobic respiration#GO:0009060;cellular respiration#GO:0045333;respiratory electron transport chain#GO:0022904;oxidative phosphorylation#GO:0006119;generation of precursor metabolites and energy#GO:0006091;electron transport chain#GO:0022900;ATP synthesis coupled electron transport#GO:0042773;cellular metabolic process#GO:0044237;cellular process#GO:0009987;energy derivation by oxidation of organic compounds#GO:0015980;metabolic process#GO:0008152 envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;respiratory chain complex#GO:0098803;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transporter complex#GO:1990351;oxidoreductase complex#GO:1990204;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;respirasome#GO:0070469;mitochondrial respiratory chain complex I#GO:0005747;protein-containing complex#GO:0032991;mitochondrial envelope#GO:0005740;mitochondrial respirasome#GO:0005746;transmembrane transporter complex#GO:1902495;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227;respiratory chain complex I#GO:0045271;NADH dehydrogenase complex#GO:0030964;mitochondrial protein-containing complex#GO:0098798 dehydrogenase#PC00092;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000011342.2|UniProtKB=F6UXM4 F6UXM4 PTHR24390:SF159 ZINC FINGER PROTEIN GROWTH FACTOR INDEPENDENT 1 TRANSCRIPTIONAL REPRESSOR sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 CIOIN|Ensembl=ENSCING00000005821.3|UniProtKB=Q1RL77 Q1RL77 Ci-PIAS-like PTHR10782:SF4 ZINC FINGER MIZ DOMAIN-CONTAINING PROTEIN TONALLI, ISOFORM E transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;SUMO transferase activity#GO:0019789;SUMO ligase activity#GO:0061665;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;protein sumoylation#GO:0016925;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;post-translational protein modification#GO:0043687;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromatin#GO:0000785;protein-DNA complex#GO:0032993;chromosome#GO:0005694;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000013560.2|UniProtKB=F6YC04 F6YC04 LOC100178594 PTHR46517:SF1 FRUCTOSE-2,6-BISPHOSPHATASE TIGAR FRUCTOSE-2,6-BISPHOSPHATASE TIGAR hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;sugar-phosphatase activity#GO:0050308;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of phosphate metabolic process#GO:0019220;regulation of amide metabolic process#GO:0034248;regulation of catabolic process#GO:0009894;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of phosphorus metabolic process#GO:0010563;negative regulation of cellular catabolic process#GO:0031330;negative regulation of metabolic process#GO:0009892;regulation of cellular catabolic process#GO:0031329;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;regulation of primary metabolic process#GO:0080090;negative regulation of catabolic process#GO:0009895;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;negative regulation of phosphate metabolic process#GO:0045936;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 phosphatase#PC00181;hydrolase#PC00121 Cobalamin biosynthesis#P02735>Ribazole-5-phosphate phosphatase#P02881 CIOIN|Ensembl=ENSCING00000014736.2|UniProtKB=F6WVH2 F6WVH2 PTHR15362:SF7 PHOSPHATIDYLINOSITOL SYNTHASE PHOSPHATIDYLSERINE SYNTHASE 2 transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000010524.3|UniProtKB=F6S294 F6S294 PTHR43975:SF2 ZGC:101858 EG:BACR7A4.14 PROTEIN-RELATED CIOIN|Ensembl=ENSCING00000007586.3|UniProtKB=F7A410 F7A410 LOC100181256 PTHR31624:SF4 UPF0472 PROTEIN C16ORF72 CHROMOSOME 16 OPEN READING FRAME 72 CIOIN|Ensembl=ENSCING00000012681.2|UniProtKB=F6U3K1 F6U3K1 evx-a PTHR46294:SF4 SEGMENTATION PROTEIN EVEN-SKIPPED SEGMENTATION PROTEIN EVEN-SKIPPED sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 CIOIN|Ensembl=ENSCING00000002165.3|UniProtKB=F6SSS9 F6SSS9 PTHR10885:SF0 ISOPENTENYL-DIPHOSPHATE DELTA-ISOMERASE ISOPENTENYL-DIPHOSPHATE DELTA-ISOMERASE isomerase#PC00135;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000022105.1|UniProtKB=H2XJX5 H2XJX5 LOC100180919 PTHR45840:SF2 RHOMBOID-RELATED PROTEIN PROTEIN RHOMBOID-RELATED CIOIN|Ensembl=ENSCING00000005147.3|UniProtKB=F6VAE3 F6VAE3 PTHR23505:SF96 SPINSTER LP14756P cellular anatomical entity#GO:0110165;membrane#GO:0016020 transporter#PC00227 CIOIN|Ensembl=ENSCING00000008406.3|UniProtKB=F6XRM9 F6XRM9 LOC100186020 PTHR11157:SF12 FATTY ACID ACYL TRANSFERASE-RELATED ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN 4 acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824 organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;monocarboxylic acid biosynthetic process#GO:0072330;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;organic acid metabolic process#GO:0006082;membrane lipid biosynthetic process#GO:0046467;sphingolipid metabolic process#GO:0006665;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;fatty acid metabolic process#GO:0006631;membrane lipid metabolic process#GO:0006643;nitrogen compound metabolic process#GO:0006807;small molecule biosynthetic process#GO:0044283;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;sphingolipid biosynthetic process#GO:0030148;fatty acid biosynthetic process#GO:0006633;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 acyltransferase#PC00042 CIOIN|Ensembl=ENSCING00000001358.3|UniProtKB=F6SX21 F6SX21 PTHR19282:SF456 TETRASPANIN CD63 MOLECULE cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000002319.3|UniProtKB=F6PP67 F6PP67 LOC100175865 PTHR13386:SF1 HISTONE PARYLATION FACTOR 1 HISTONE PARYLATION FACTOR 1 carbohydrate derivative binding#GO:0097367;protein binding#GO:0005515;binding#GO:0005488;histone binding#GO:0042393 response to stimulus#GO:0050896;DNA damage response#GO:0006974;cellular response to stimulus#GO:0051716;response to stress#GO:0006950;regulation of molecular function#GO:0065009;biological regulation#GO:0065007;cellular process#GO:0009987;cellular response to stress#GO:0033554;regulation of catalytic activity#GO:0050790;regulation of transferase activity#GO:0051338 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077;histone modifying enzyme#PC00261 CIOIN|Ensembl=ENSCING00000009593.3|UniProtKB=L7N0T8 L7N0T8 PTHR23220:SF133 INTEGRIN ALPHA INTEGRIN ALPHA-PS2 cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;integrin binding#GO:0005178;binding#GO:0005488;signaling receptor binding#GO:0005102 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cell adhesion mediated by integrin#GO:0033627;cell-cell adhesion#GO:0098609;cell communication#GO:0007154;cell adhesion#GO:0007155;cell-substrate adhesion#GO:0031589;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cell-matrix adhesion#GO:0007160;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;integrin-mediated signaling pathway#GO:0007229;biological regulation#GO:0065007;signaling#GO:0023052 receptor complex#GO:0043235;membrane protein complex#GO:0098796;external side of plasma membrane#GO:0009897;cell surface#GO:0009986;protein-containing complex#GO:0032991;plasma membrane signaling receptor complex#GO:0098802;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 cell adhesion molecule#PC00069;integrin#PC00126 Integrin signalling pathway#P00034>Integrin alpha#P00941 CIOIN|Ensembl=ENSCING00000000992.3|UniProtKB=F6YLQ9 F6YLQ9 PTHR42753:SF10 MITOCHONDRIAL RIBOSOME PROTEIN L39/PROLYL-TRNA LIGASE FAMILY MEMBER PROLINE--TRNA LIGASE, MITOCHONDRIAL-RELATED catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;ligase activity#GO:0016874;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;peptide biosynthetic process#GO:0043043;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 aminoacyl-tRNA synthetase#PC00047;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000015955.2|UniProtKB=F6X4I5 F6X4I5 PTHR45752:SF196 LEUCINE-RICH REPEAT-CONTAINING GH17740P scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000006519.3|UniProtKB=F6PUP9 F6PUP9 PTHR24416:SF611 TYROSINE-PROTEIN KINASE RECEPTOR TYROSINE-PROTEIN KINASE TRANSMEMBRANE RECEPTOR ROR transmembrane signal receptor#PC00197 CIOIN|Ensembl=ENSCING00000004300.3|UniProtKB=F6TSV6 F6TSV6 PTHR19862:SF14 WD REPEAT-CONTAINING PROTEIN 48 WD REPEAT-CONTAINING PROTEIN 48 protein binding#GO:0005515;ubiquitin-like protein binding#GO:0032182;binding#GO:0005488;ubiquitin binding#GO:0043130 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;double-strand break repair via homologous recombination#GO:0000724;nucleobase-containing compound metabolic process#GO:0006139;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;DNA damage response#GO:0006974;response to stress#GO:0006950;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;recombinational repair#GO:0000725;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 CIOIN|Ensembl=ENSCING00000007414.3|UniProtKB=F7B890 F7B890 PTHR14881:SF4 LISH DOMAIN-CONTAINING PROTEIN ARMC9 LISH DOMAIN-CONTAINING PROTEIN ARMC9 organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cell projection organization#GO:0030030;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;microtubule cytoskeleton#GO:0015630;ciliary basal body#GO:0036064;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;centriole#GO:0005814;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cilium#GO:0005929;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;microtubule or microtubule-binding cytoskeletal protein#PC00157 CIOIN|Ensembl=ENSCING00000007109.3|UniProtKB=F6SWW8 F6SWW8 PTHR11819:SF195 SOLUTE CARRIER FAMILY 5 SODIUM_GLUCOSE COTRANSPORTER 4 inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;carbohydrate transmembrane transporter activity#GO:0015144;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;sugar transmembrane transporter activity#GO:0051119;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;active transmembrane transporter activity#GO:0022804;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;active monoatomic ion transmembrane transporter activity#GO:0022853;monoatomic ion transmembrane transporter activity#GO:0015075;inorganic cation transmembrane transporter activity#GO:0022890;solute:monoatomic cation symporter activity#GO:0015294 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000008759.3|UniProtKB=F6T090 F6T090 LOC113474037 PTHR45742:SF8 COMPLEMENT COMPONENT C6 FLOCCULATION PROTEIN FLO11 complement component#PC00078 CIOIN|Ensembl=ENSCING00000020910.1|UniProtKB=H2Y0X6 H2Y0X6 LOC100183714 PTHR14511:SF14 G PROTEIN COUPLED RECEPTOR, CLASS C, GROUP 5 G-PROTEIN COUPLED RECEPTOR FAMILY C GROUP 5 MEMBER B-LIKE protein kinase activator activity#GO:0030295;molecular function activator activity#GO:0140677;protein kinase regulator activity#GO:0019887;molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047;kinase regulator activity#GO:0019207;enzyme regulator activity#GO:0030234;kinase activator activity#GO:0019209 receptor complex#GO:0043235;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;extracellular region#GO:0005576;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 CIOIN|Ensembl=ENSCING00000011275.2|UniProtKB=F6YSQ6 F6YSQ6 PTHR22883:SF203 ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN PALMITOYLTRANSFERASE palmitoyltransferase activity#GO:0016409;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular localization#GO:0051641;macromolecule localization#GO:0033036;macromolecule modification#GO:0043412;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;biosynthetic process#GO:0009058;establishment of protein localization#GO:0045184;establishment of protein localization to membrane#GO:0090150;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;protein palmitoylation#GO:0018345;protein metabolic process#GO:0019538;protein lipidation#GO:0006497;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;localization within membrane#GO:0051668;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein localization to membrane#GO:0072657;organonitrogen compound biosynthetic process#GO:1901566;protein targeting#GO:0006605;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;protein acylation#GO:0043543;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;lipoprotein biosynthetic process#GO:0042158;protein localization#GO:0008104;primary metabolic process#GO:0044238;localization#GO:0051179;protein targeting to membrane#GO:0006612;cellular macromolecule localization#GO:0070727;lipoprotein metabolic process#GO:0042157 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000006737.1|UniProtKB=F6YL99 F6YL99 LOC100182101 PTHR31909:SF3 CHROMOSOME 20 ORF85 FAMILY MEMBER SIMILAR TO PROTEIN C20ORF85 HOMOLOG CIOIN|Ensembl=ENSCING00000001622.3|UniProtKB=F7B8Y3 F7B8Y3 PTHR22738:SF10 RASSF RAS ASSOCIATION DOMAIN-CONTAINING PROTEIN 1 HOMOLOG regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000010358.3|UniProtKB=F6PHG8 F6PHG8 PTHR12137:SF54 CARBOHYDRATE SULFOTRANSFERASE CARBOHYDRATE SULFOTRANSFERASE sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824 transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000000552.3|UniProtKB=F6Q7R7 F6Q7R7 LOC104266587 PTHR11863:SF226 STEROL DESATURASE FATTY ACID HYDROXYLASE DOMAIN-CONTAINING PROTEIN 2-RELATED oxidase#PC00175;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000008813.3|UniProtKB=F7BJC2 F7BJC2 PTHR23090:SF9 NH 3 /GLUTAMINE-DEPENDENT NAD + SYNTHETASE GLUTAMINE-DEPENDENT NAD(+) SYNTHETASE cellular aromatic compound metabolic process#GO:0006725;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;pyridine nucleotide metabolic process#GO:0019362;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;nucleotide biosynthetic process#GO:0009165;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;pyridine-containing compound metabolic process#GO:0072524;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;nicotinamide nucleotide metabolic process#GO:0046496;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ligase#PC00142;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000008797.3|UniProtKB=F6SC57 F6SC57 LOC100185562 PTHR11937:SF571 ACTIN ACTIN, CYTOSKELETAL 1B actin and actin related protein#PC00039;cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 Integrin signalling pathway#P00034>Actin#P00944;Alzheimer disease-presenilin pathway#P00004>actin#P00114;Nicotinic acetylcholine receptor signaling pathway#P00044>Actin#P01090;Huntington disease#P00029>Actin#P00807;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>F-actin#P00858;Cadherin signaling pathway#P00012>F-actin#P00470;Cytoskeletal regulation by Rho GTPase#P00016>Actin#P00512 CIOIN|Ensembl=ENSCING00000024681.1|UniProtKB=H2XJL0 H2XJL0 LOC100175186 PTHR11662:SF399 SOLUTE CARRIER FAMILY 17 FI19708P1-RELATED secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000006847.3|UniProtKB=F7AFI4 F7AFI4 LOC100180854 PTHR10264:SF127 BAND 7 PROTEIN-RELATED PODOCIN cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cytoskeletal protein#PC00085 CIOIN|Ensembl=ENSCING00000022677.1|UniProtKB=H2XSZ1 H2XSZ1 PTHR13829:SF2 SNRNP CORE PROTEIN FAMILY MEMBER U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM2 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;mRNA splicing, via spliceosome#GO:0000398;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 supramolecular complex#GO:0099080;catalytic step 2 spliceosome#GO:0071013;U6 snRNP#GO:0005688;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;P-body#GO:0000932;catalytic complex#GO:1902494;U4/U6 x U5 tri-snRNP complex#GO:0046540;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic ribonucleoprotein granule#GO:0036464;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;spliceosomal snRNP complex#GO:0097525;small nuclear ribonucleoprotein complex#GO:0030532;protein-containing complex#GO:0032991;spliceosomal tri-snRNP complex#GO:0097526;precatalytic spliceosome#GO:0071011;membrane-bounded organelle#GO:0043227;Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513 RNA splicing factor#PC00148;RNA processing factor#PC00147;RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000005212.3|UniProtKB=A0A1W2W8E5 A0A1W2W8E5 LOC100185398 PTHR11937:SF274 ACTIN BRAHMA ASSOCIATED PROTEIN 55KD actin and actin related protein#PC00039;cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 CIOIN|Ensembl=ENSCING00000014451.2|UniProtKB=F7BH80 F7BH80 PTHR10233:SF14 TRANSLATION INITIATION FACTOR EIF-2B TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT DELTA translation initiation factor#PC00224;translation factor#PC00223 CIOIN|Ensembl=ENSCING00000007249.3|UniProtKB=F6UW56 F6UW56 PTHR45627:SF8 ADENYLATE CYCLASE TYPE 1 ADENYLATE CYCLASE TYPE 9 adenylate cyclase activity#GO:0004016;lyase activity#GO:0016829;cyclase activity#GO:0009975;phosphorus-oxygen lyase activity#GO:0016849;catalytic activity#GO:0003824 regulation of biological process#GO:0050789;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 cyclase#PC00079;adenylate cyclase#PC00043;lyase#PC00144 Endothelin signaling pathway#P00019>Adenylate cyclase#P00569;GABA-B receptor II signaling#P05731>AC#P05760;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>cAMP cyclase#P00719 CIOIN|Ensembl=ENSCING00000013751.2|UniProtKB=F6Z4R3 F6Z4R3 PTHR23282:SF142 APICAL ENDOSOMAL GLYCOPROTEIN PRECURSOR. MAM DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000008891.3|UniProtKB=F6QX49 F6QX49 PTHR10161:SF14 TARTRATE-RESISTANT ACID PHOSPHATASE TYPE 5 TARTRATE-RESISTANT ACID PHOSPHATASE TYPE 5 hydrolase#PC00121;phosphatase#PC00181 CIOIN|Ensembl=ENSCING00000011581.2|UniProtKB=A0A1W3JLL0 A0A1W3JLL0 LOC108951018 PTHR20981:SF6 60S RIBOSOMAL PROTEIN L21 60S RIBOSOMAL PROTEIN L21 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic large ribosomal subunit#GO:0022625;large ribosomal subunit#GO:0015934;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000014831.2|UniProtKB=F6S8P8 F6S8P8 LOC100183881 PTHR10857:SF138 COPINE COPINE-3 lipid binding#GO:0008289;phospholipid binding#GO:0005543;binding#GO:0005488 response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;cellular process#GO:0009987;response to chemical#GO:0042221 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 calcium-binding protein#PC00060 CIOIN|Ensembl=ENSCING00000003852.3|UniProtKB=F6YPY1 F6YPY1 PTHR24116:SF0 KINASE D-INTERACTING SUBSTRATE OF 220 KDA KINASE D-INTERACTING SUBSTRATE OF 220 KDA protein binding#GO:0005515;protein kinase regulator activity#GO:0019887;binding#GO:0005488;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207 CIOIN|Ensembl=ENSCING00000007091.3|UniProtKB=F6VLN4 F6VLN4 LOC100187157 PTHR23077:SF171 AAA-FAMILY ATPASE NUCLEAR VALOSIN-CONTAINING PROTEIN-LIKE pyrophosphatase activity#GO:0016462;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;ATP hydrolysis activity#GO:0016887 primary active transporter#PC00068;transporter#PC00227 CIOIN|Ensembl=ENSCING00000023335.1|UniProtKB=H2XM81 H2XM81 LOC104265505 PTHR14401:SF6 CENTROMERE PROTEIN K CENTROMERE PROTEIN K nuclear chromosome segregation#GO:0098813;sister chromatid segregation#GO:0000819;nuclear division#GO:0000280;cell cycle process#GO:0022402;cellular component organization#GO:0016043;cellular process#GO:0009987;mitotic cell cycle process#GO:1903047;chromosome segregation#GO:0007059;cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;chromosome organization#GO:0051276;organelle organization#GO:0006996;mitotic nuclear division#GO:0140014;organelle fission#GO:0048285;cell cycle#GO:0007049;mitotic sister chromatid segregation#GO:0000070 CIOIN|Ensembl=ENSCING00000022617.1|UniProtKB=H2XTG7 H2XTG7 LOC101242260 PTHR12056:SF2 DNA-DIRECTED RNA POLYMERASES I, II, AND III GEO11084P1 catalytic activity, acting on RNA#GO:0140098;5'-3' RNA polymerase activity#GO:0034062;transferase activity#GO:0016740;DNA-directed 5'-3' RNA polymerase activity#GO:0003899;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;RNA polymerase activity#GO:0097747;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring phosphorus-containing groups#GO:0016772;RNA polymerase III activity#GO:0001056;RNA polymerase II activity#GO:0001055;RNA polymerase I activity#GO:0001054 membrane-enclosed lumen#GO:0031974;RNA polymerase II, core complex#GO:0005665;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;DNA-directed RNA polymerase complex#GO:0000428;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular protein-containing complex#GO:0140535;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695;RNA polymerase II, holoenzyme#GO:0016591;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;RNA polymerase complex#GO:0030880;protein-containing complex#GO:0032991;RNA polymerase III complex#GO:0005666;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;RNA polymerase I complex#GO:0005736;nuclear protein-containing complex#GO:0140513 RNA metabolism protein#PC00031;DNA-directed RNA polymerase#PC00019 CIOIN|Ensembl=ENSCING00000018477.1|UniProtKB=H2XTR7 H2XTR7 PTHR10896:SF65 GALACTOSYLGALACTOSYLXYLOSYLPROTEIN 3-BETA-GLUCURONOSYLTRANSFERASE BETA-1,3-GLUCURONYLTRANSFERASE GALACTOSYLGALACTOSYLXYLOSYLPROTEIN 3-BETA-GLUCURONOSYLTRANSFERASE 3 carbohydrate metabolic process#GO:0005975;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;primary metabolic process#GO:0044238 cytoplasm#GO:0005737;bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;Golgi membrane#GO:0000139;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111 CIOIN|Ensembl=ENSCING00000007018.3|UniProtKB=F7AEB8 F7AEB8 LOC100175875 PTHR23023:SF266 DIMETHYLANILINE MONOOXYGENASE FLAVIN-CONTAINING MONOOXYGENASE oxygenase#PC00177;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000005736.3|UniProtKB=F6U1Q3 F6U1Q3 LOC100184399 PTHR11035:SF3 VERY-LONG-CHAIN (3R)-3-HYDROXYACYL-COA DEHYDRATASE VERY-LONG-CHAIN (3R)-3-HYDROXYACYL-COA DEHYDRATASE lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835;hydro-lyase activity#GO:0016836;catalytic activity#GO:0003824 organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;monocarboxylic acid biosynthetic process#GO:0072330;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;organic acid metabolic process#GO:0006082;membrane lipid biosynthetic process#GO:0046467;sphingolipid metabolic process#GO:0006665;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;fatty acid metabolic process#GO:0006631;membrane lipid metabolic process#GO:0006643;nitrogen compound metabolic process#GO:0006807;small molecule biosynthetic process#GO:0044283;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;sphingolipid biosynthetic process#GO:0030148;fatty acid biosynthetic process#GO:0006633;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 dehydratase#PC00091;lyase#PC00144 CIOIN|Ensembl=ENSCING00000019315.1|UniProtKB=Q4H2S2 Q4H2S2 Ci-SoxB2 PTHR10270:SF324 SOX TRANSCRIPTION FACTOR SOX DOMAIN-CONTAINING PROTEIN DICHAETE-RELATED DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;cell differentiation#GO:0030154;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA metabolic process#GO:0051252;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;positive regulation of RNA metabolic process#GO:0051254;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;HMG box transcription factor#PC00024 CIOIN|Ensembl=ENSCING00000014077.1|UniProtKB=F6U0W4 F6U0W4 PTHR24243:SF234 G-PROTEIN COUPLED RECEPTOR GROWTH HORMONE SECRETAGOGUE RECEPTOR TYPE 1-LIKE signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 CIOIN|Ensembl=ENSCING00000021920.1|UniProtKB=H2XYP3 H2XYP3 LOC100180936 PTHR12425:SF5 SYNEMBRYN SYNEMBRYN nucleoside-triphosphatase regulator activity#GO:0060589;protein binding#GO:0005515;GTPase regulator activity#GO:0030695;binding#GO:0005488;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000003713.3|UniProtKB=F7BEV9 F7BEV9 LOC100179989 PTHR13832:SF533 PROTEIN PHOSPHATASE 2C TGF-BETA-ACTIVATED KINASE 1 AND MAP3K7-BINDING PROTEIN 1 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;dephosphorylation#GO:0016311;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein dephosphorylation#GO:0006470;cellular metabolic process#GO:0044237;cellular process#GO:0009987;protein metabolic process#GO:0019538;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 protein phosphatase#PC00195;protein modifying enzyme#PC00260 TGF-beta signaling pathway#P00052>TAB#P01290;p38 MAPK pathway#P05918>TAB1#P06035;Toll receptor signaling pathway#P00054>TAB1#P01365 CIOIN|Ensembl=ENSCING00000008573.3|UniProtKB=F6SWH7 F6SWH7 zf(ring)-20 PTHR12616:SF1 VACUOLAR PROTEIN SORTING VPS41 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 41 HOMOLOG vesicle fusion#GO:0006906;cellular localization#GO:0051641;macroautophagy#GO:0016236;macromolecule localization#GO:0033036;protein targeting to vacuole#GO:0006623;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;transport#GO:0006810;nitrogen compound transport#GO:0071705;response to extracellular stimulus#GO:0009991;establishment of protein localization#GO:0045184;process utilizing autophagic mechanism#GO:0061919;organic substance transport#GO:0071702;cellular response to starvation#GO:0009267;establishment of localization#GO:0051234;catabolic process#GO:0009056;vesicle organization#GO:0016050;protein localization to organelle#GO:0033365;cellular response to extracellular stimulus#GO:0031668;organelle fusion#GO:0048284;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;establishment of protein localization to vacuole#GO:0072666;cellular response to stimulus#GO:0051716;vacuolar transport#GO:0007034;protein localization to vacuole#GO:0072665;protein targeting#GO:0006605;vesicle-mediated transport#GO:0016192;cellular metabolic process#GO:0044237;establishment of protein localization to organelle#GO:0072594;cell communication#GO:0007154;cellular component organization#GO:0016043;response to nutrient levels#GO:0031667;cellular process#GO:0009987;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;cellular macromolecule localization#GO:0070727;response to stress#GO:0006950;membrane fusion#GO:0061025;organelle organization#GO:0006996;cellular response to nutrient levels#GO:0031669;response to starvation#GO:0042594;protein transport#GO:0015031;cellular response to external stimulus#GO:0071496;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;cellular response to stress#GO:0033554;autophagy#GO:0006914 membrane protein complex#GO:0098796;endosome#GO:0005768;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;vesicle tethering complex#GO:0099023;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;late endosome#GO:0005770 membrane traffic protein#PC00150 CIOIN|Ensembl=ENSCING00000003884.3|UniProtKB=F6TXE7 F6TXE7 PTHR14965:SF7 SI:CH73-248E21.1 SUBFAMILY NOT NAMED CIOIN|Ensembl=ENSCING00000008045.3|UniProtKB=F6S4Y6 F6S4Y6 LOC100186662 PTHR45995:SF1 FAMILY NOT NAMED PEPTIDYL-PROLYL CIS-TRANS ISOMERASE NIMA-INTERACTING 4 CIOIN|Ensembl=ENSCING00000021826.1|UniProtKB=H2XJU0 H2XJU0 PTHR24351:SF202 RIBOSOMAL PROTEIN S6 KINASE CHROMOSOMAL SERINE_THREONINE-PROTEIN KINASE JIL-1 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>P90 RSK#P00888;PDGF signaling pathway#P00047>p90RSK#P01142 CIOIN|Ensembl=ENSCING00000021564.1|UniProtKB=H2XLR3 H2XLR3 LOC100185859 PTHR23407:SF6 ATPASE INHIBITOR/5-FORMYLTETRAHYDROFOLATE CYCLO-LIGASE ATPASE INHIBITOR, MITOCHONDRIAL ligase activity#GO:0016874;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;folic acid-containing compound metabolic process#GO:0006760;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;heterocycle biosynthetic process#GO:0018130;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;cellular modified amino acid metabolic process#GO:0006575;aromatic compound biosynthetic process#GO:0019438;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ligase#PC00142;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000008581.3|UniProtKB=F6UDM9 F6UDM9 PTHR11005:SF161 LYSOSOMAL ACID LIPASE-RELATED LIPASE lipase#PC00143;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000024623.1|UniProtKB=H2XMI4 H2XMI4 LOC100181482 PTHR34876:SF4 FAMILY NOT NAMED 1,4-BETA-D-GLUCAN CELLOBIOHYDROLASE C-RELATED CIOIN|Ensembl=ENSCING00000001886.3|UniProtKB=A0A1W2WAD0 A0A1W2WAD0 LOC100176145 PTHR45963:SF2 RE52028P RE52028P CIOIN|Ensembl=ENSCING00000002721.3|UniProtKB=F7BII5 F7BII5 PTHR22588:SF3 VWFA DOMAIN-CONTAINING PROTEIN VWFA DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000004950.3|UniProtKB=F7A6L3 F7A6L3 PTHR12461:SF42 HYPOXIA-INDUCIBLE FACTOR 1 ALPHA INHIBITOR-RELATED JMJC DOMAIN-CONTAINING PROTEIN protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000002339.3|UniProtKB=F6PNI9 F6PNI9 PTHR24072:SF359 RHO FAMILY GTPASE RAS-RELATED PROTEIN RAC1-RELATED GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;enzyme binding#GO:0019899;ribonucleoside triphosphate phosphatase activity#GO:0017111;kinase binding#GO:0019900;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;protein kinase binding#GO:0019901;anion binding#GO:0043168;ion binding#GO:0043167 establishment or maintenance of cell polarity#GO:0007163;regulation of anatomical structure morphogenesis#GO:0022603;regulation of organelle organization#GO:0033043;regulation of cellular component organization#GO:0051128;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of cytoskeleton organization#GO:0051493;regulation of cell shape#GO:0008360;regulation of biological quality#GO:0065008;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;cortical cytoskeleton organization#GO:0030865;biological regulation#GO:0065007;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;regulation of actin filament-based process#GO:0032970 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 small GTPase#PC00208 T cell activation#P00053>rac#P01324;Huntington disease#P00029>Rac#P00775;Cytoskeletal regulation by Rho GTPase#P00016>Rac#P00523;EGF receptor signaling pathway#P00018>Rac#P00564;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Cdc42#P00834;Ras Pathway#P04393>Rac#P04559;Axon guidance mediated by netrin#P00009>Rac#P00366;Integrin signalling pathway#P00034>Rac#P00927;Axon guidance mediated by Slit/Robo#P00008>Rac#P00354;FGF signaling pathway#P00021>Rac#P00645 CIOIN|Ensembl=ENSCING00000021685.1|UniProtKB=H2XNI6 H2XNI6 PTHR22792:SF62 LUPUS LA PROTEIN-RELATED LA-RELATED PROTEIN 7 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000012565.2|UniProtKB=F7AZY1 F7AZY1 PTHR18952:SF141 CARBONIC ANHYDRASE CARBONIC ANHYDRASE carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829;hydro-lyase activity#GO:0016836;catalytic activity#GO:0003824 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 dehydratase#PC00091;lyase#PC00144 CIOIN|Ensembl=ENSCING00000009521.3|UniProtKB=F6WWW4 F6WWW4 PTHR19854:SF15 TRANSDUCIN BETA-LIKE 3 TRANSDUCIN BETA-LIKE PROTEIN 3 snoRNA binding#GO:0030515;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;RNA processing#GO:0006396;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;ribosome biogenesis#GO:0042254;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;maturation of SSU-rRNA#GO:0030490;ribosomal small subunit biogenesis#GO:0042274 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;nuclear lumen#GO:0031981;90S preribosome#GO:0030686 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000008711.3|UniProtKB=F6WCA3 F6WCA3 PTHR45818:SF3 PROTEIN VAV PROTEIN VAV nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;guanyl-nucleotide exchange factor activity#GO:0005085 biological regulation#GO:0065007;regulation of hydrolase activity#GO:0051336;regulation of catalytic activity#GO:0050790;regulation of GTPase activity#GO:0043087;regulation of molecular function#GO:0065009 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 PDGF signaling pathway#P00047>Vav#P01169 CIOIN|Ensembl=ENSCING00000019114.1|UniProtKB=H2XVP2 H2XVP2 PTHR11844:SF25 METALLOPROTEASE INHIBITOR NTR DOMAIN-CONTAINING PROTEIN peptidase inhibitor activity#GO:0030414;protease binding#GO:0002020;binding#GO:0005488;molecular function regulator activity#GO:0098772;enzyme binding#GO:0019899;protein binding#GO:0005515;peptidase regulator activity#GO:0061134;enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;endopeptidase regulator activity#GO:0061135;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234 negative regulation of hydrolase activity#GO:0051346;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;regulation of catabolic process#GO:0009894;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of protein catabolic process#GO:0042177;regulation of protein catabolic process#GO:0042176;regulation of catalytic activity#GO:0050790;regulation of biological process#GO:0050789;regulation of molecular function#GO:0065009;regulation of hydrolase activity#GO:0051336;negative regulation of cellular process#GO:0048523;response to organic substance#GO:0010033;regulation of proteolysis#GO:0030162;negative regulation of endopeptidase activity#GO:0010951;negative regulation of peptidase activity#GO:0010466;negative regulation of cellular catabolic process#GO:0031330;negative regulation of metabolic process#GO:0009892;negative regulation of proteolysis#GO:0045861;regulation of cellular catabolic process#GO:0031329;negative regulation of protein metabolic process#GO:0051248;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;negative regulation of catabolic process#GO:0009895;regulation of macromolecule metabolic process#GO:0060255;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of endopeptidase activity#GO:0052548;regulation of peptidase activity#GO:0052547;negative regulation of catalytic activity#GO:0043086;regulation of metabolic process#GO:0019222;negative regulation of molecular function#GO:0044092;regulation of cellular metabolic process#GO:0031323 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;extracellular space#GO:0005615;extracellular region#GO:0005576 protease inhibitor#PC00191 CIOIN|Ensembl=ENSCING00000011899.2|UniProtKB=F6VYU2 F6VYU2 PTHR24416:SF539 TYROSINE-PROTEIN KINASE RECEPTOR RECEPTOR PROTEIN-TYROSINE KINASE signaling receptor activity#GO:0038023;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;molecular transducer activity#GO:0060089;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672;transmembrane signaling receptor activity#GO:0004888 signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;positive regulation of cellular metabolic process#GO:0031325;developmental process#GO:0032502;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;regulation of molecular function#GO:0065009;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;positive regulation of phosphorylation#GO:0042327;cellular response to stimulus#GO:0051716;positive regulation of catalytic activity#GO:0043085;multicellular organism development#GO:0007275;positive regulation of phosphorus metabolic process#GO:0010562;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphate metabolic process#GO:0045937;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;multicellular organismal process#GO:0032501;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 receptor complex#GO:0043235;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 CIOIN|Ensembl=ENSCING00000021856.1|UniProtKB=H2XQP6 H2XQP6 PTHR45935:SF21 PROTEIN ZBED8-RELATED DUF4371 DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000008242.3|UniProtKB=F6R4T5 F6R4T5 PTHR11864:SF0 PRE-MRNA-PROCESSING PROTEIN PRP40 PRP40 PRE-MRNA PROCESSING FACTOR 40 HOMOLOG A (YEAST) nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;mRNA splicing, via spliceosome#GO:0000398;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;U1 snRNP#GO:0005685;U2-type spliceosomal complex#GO:0005684;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;spliceosomal snRNP complex#GO:0097525;small nuclear ribonucleoprotein complex#GO:0030532;protein-containing complex#GO:0032991;U2-type prespliceosome#GO:0071004;membrane-bounded organelle#GO:0043227;Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513 CIOIN|Ensembl=ENSCING00000005244.3|UniProtKB=F6PYR8 F6PYR8 LOC100186085 PTHR12422:SF1 GH09096P GH09096P CIOIN|Ensembl=ENSCING00000004839.3|UniProtKB=F6TZ23 F6TZ23 PTHR44414:SF1 PROTEIN NEDD1 PROTEIN NEDD1 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;microtubule cytoskeleton organization#GO:0000226;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;microtubule polymerization or depolymerization#GO:0031109;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;microtubule-based process#GO:0007017;microtubule polymerization#GO:0046785;protein-containing complex organization#GO:0043933;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;protein polymerization#GO:0051258;cell cycle#GO:0007049;cytoskeleton organization#GO:0007010;microtubule nucleation#GO:0007020 spindle pole#GO:0000922;microtubule organizing center#GO:0005815;cellular anatomical entity#GO:0110165;centriole#GO:0005814;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;centrosome#GO:0005813;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;ciliary basal body#GO:0036064;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;cell projection#GO:0042995;cilium#GO:0005929;spindle#GO:0005819 CIOIN|Ensembl=ENSCING00000001019.2|UniProtKB=Q70W02 Q70W02 soxE PTHR45803:SF10 SOX100B HMG BOX DOMAIN-CONTAINING PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;epithelium development#GO:0060429;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;regulation of biosynthetic process#GO:0009889;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;negative regulation of biosynthetic process#GO:0009890;regulation of DNA-templated transcription#GO:0006355;negative regulation of metabolic process#GO:0009892;tissue development#GO:0009888;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;tissue morphogenesis#GO:0048729;morphogenesis of an epithelium#GO:0002009;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;HMG box transcription factor#PC00024 CIOIN|Ensembl=ENSCING00000005314.3|UniProtKB=F7BQ53 F7BQ53 PTHR19924:SF26 UTP15 U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 15 FAMILY MEMBER U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 15 HOMOLOG cellular aromatic compound metabolic process#GO:0006725;positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of transcription by RNA polymerase I#GO:0045943;cellular component biogenesis#GO:0044085;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;positive regulation of cellular metabolic process#GO:0031325;RNA processing#GO:0006396;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;ribosome biogenesis#GO:0042254;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;regulation of transcription by RNA polymerase I#GO:0006356;macromolecule biosynthetic process#GO:0009059;regulation of DNA-templated transcription#GO:0006355;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;rRNA metabolic process#GO:0016072;regulation of cellular process#GO:0050794;ribonucleoprotein complex biogenesis#GO:0022613;biological regulation#GO:0065007;positive regulation of RNA metabolic process#GO:0051254;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA processing factor#PC00147 CIOIN|Ensembl=ENSCING00000000774.3|UniProtKB=F6PH94 F6PH94 PTHR10151:SF126 ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE ECTONUCLEOTIDE PYROPHOSPHATASE_PHOSPHODIESTERASE FAMILY MEMBER 7-LIKE metabolite interconversion enzyme#PC00262;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000015207.2|UniProtKB=H2XX98 H2XX98 PTHR43696:SF9 COILED-COIL DOMAIN-CONTAINING PROTEIN 157 COILED-COIL DOMAIN-CONTAINING PROTEIN 157 CIOIN|Ensembl=ENSCING00000004882.3|UniProtKB=F6SP24 F6SP24 PTHR46458:SF1 BLR2807 PROTEIN GEO09476P1 transporter#PC00227 CIOIN|Ensembl=ENSCING00000004249.3|UniProtKB=F6YG13 F6YG13 PTHR18945:SF835 NEUROTRANSMITTER GATED ION CHANNEL GAMMA-AMINOBUTYRIC ACID RECEPTOR ALPHA-LIKE ligand-gated ion channel#PC00141;ion channel#PC00133;transporter#PC00227 CIOIN|Ensembl=ENSCING00000021675.1|UniProtKB=H2XVJ7 H2XVJ7 PTHR21072:SF13 GPI TRANSAMIDASE COMPONENT PIG-S GPI TRANSAMIDASE COMPONENT PIG-S lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;phospholipid biosynthetic process#GO:0008654;macromolecule modification#GO:0043412;phosphatidylinositol biosynthetic process#GO:0006661;organophosphate biosynthetic process#GO:0090407;glycolipid metabolic process#GO:0006664;protein modification process#GO:0036211;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;lipid biosynthetic process#GO:0008610;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;protein lipidation#GO:0006497;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;glycerolipid biosynthetic process#GO:0045017;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;glycerophospholipid metabolic process#GO:0006650;phosphatidylinositol metabolic process#GO:0046488;organic substance biosynthetic process#GO:1901576;liposaccharide metabolic process#GO:1903509;cellular process#GO:0009987;membrane lipid biosynthetic process#GO:0046467;GPI anchor metabolic process#GO:0006505;lipoprotein biosynthetic process#GO:0042158;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;GPI anchor biosynthetic process#GO:0006506;membrane lipid metabolic process#GO:0006643;glycerophospholipid biosynthetic process#GO:0046474;glycolipid biosynthetic process#GO:0009247;organophosphate metabolic process#GO:0019637;lipoprotein metabolic process#GO:0042157;cellular lipid metabolic process#GO:0044255 membrane protein complex#GO:0098796;peptidase complex#GO:1905368;endoplasmic reticulum protein-containing complex#GO:0140534;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;endopeptidase complex#GO:1905369;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 CIOIN|Ensembl=ENSCING00000001983.3|UniProtKB=F6XGD9 F6XGD9 LOC100186574 PTHR11814:SF272 SULFATE TRANSPORTER SOLUTE CARRIER FAMILY 26 MEMBER 10P-RELATED inorganic molecular entity transmembrane transporter activity#GO:0015318;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;organic acid transmembrane transporter activity#GO:0005342;chloride transmembrane transporter activity#GO:0015108;monoatomic anion transmembrane transporter activity#GO:0008509;organic anion transmembrane transporter activity#GO:0008514;inorganic anion transmembrane transporter activity#GO:0015103;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 transporter#PC00227 CIOIN|Ensembl=ENSCING00000002812.3|UniProtKB=F6WZU2 F6WZU2 PTHR10513:SF35 DEOXYNUCLEOSIDE KINASE DEOXYADENOSINE KINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 nucleotide kinase#PC00172 CIOIN|Ensembl=ENSCING00000014910.2|UniProtKB=F6Y7Y1 F6Y7Y1 PTHR43827:SF3 2,5-DIKETO-D-GLUCONIC ACID REDUCTASE NADP-DEPENDENT OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 reductase#PC00198;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000012376.2|UniProtKB=F6Z8U5 F6Z8U5 PTHR15497:SF1 3-HYDROXYANTHRANILATE 3,4-DIOXYGENASE 3-HYDROXYANTHRANILATE 3,4-DIOXYGENASE oxygenase#PC00177;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000001094.3|UniProtKB=F7AZQ1 F7AZQ1 LOC494385 PTHR10489:SF932 CELL ADHESION MOLECULE G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN cell adhesion molecule#PC00069 CIOIN|Ensembl=ENSCING00000013608.2|UniProtKB=F6V1U5 F6V1U5 LOC100178157 PTHR11852:SF0 PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE IB SUBUNIT BETA HOMOLOG protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000013041.2|UniProtKB=F6TSW4 F6TSW4 PTHR14647:SF87 GALACTOSE-3-O-SULFOTRANSFERASE PUTATIVE-RELATED transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000000718.3|UniProtKB=F7AMU0 F7AMU0 PTHR45828:SF33 CYTOCHROME B561/FERRIC REDUCTASE TRANSMEMBRANE DOMON DOMAIN-CONTAINING PROTEIN cellular anatomical entity#GO:0110165;membrane#GO:0016020 reductase#PC00198;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000018952.1|UniProtKB=H2XKC5 H2XKC5 PTHR11984:SF53 CONNEXIN GAP JUNCTION PROTEIN wide pore channel activity#GO:0022829;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;channel activity#GO:0015267 biological regulation#GO:0065007;regulation of biological process#GO:0050789;cell communication#GO:0007154;cellular process#GO:0009987;cell-cell signaling#GO:0007267;signaling#GO:0023052 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 cell junction protein#PC00070;gap junction#PC00105 CIOIN|Ensembl=ENSCING00000024490.1|UniProtKB=H2XZJ2 H2XZJ2 LOC100187178 PTHR23049:SF57 MYOSIN REGULATORY LIGHT CHAIN 2 MYOSIN REGULATORY LIGHT CHAIN 12A cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;myosin binding#GO:0017022;binding#GO:0005488 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;myosin complex#GO:0016459;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 CIOIN|Ensembl=ENSCING00000007939.3|UniProtKB=F6Z7V5 F6Z7V5 LOC100180469 PTHR11699:SF303 ALDEHYDE DEHYDROGENASE-RELATED RETINAL DEHYDROGENASE 2 oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 dehydrogenase#PC00092;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000019008.1|UniProtKB=A0A1W2W793 A0A1W2W793 LOC100175838 PTHR13417:SF2 E3 UBIQUITIN-PROTEIN LIGASE RNF146 E3 UBIQUITIN-PROTEIN LIGASE RNF146 carbohydrate derivative binding#GO:0097367;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000023708.1|UniProtKB=H2XX26 H2XX26 LOC100181844 PTHR22802:SF379 C-TYPE LECTIN SUPERFAMILY MEMBER CHONDROITIN SULFATE PROTEOGLYCAN 2 ISOFORM X1 membrane traffic protein#PC00150 CIOIN|Ensembl=ENSCING00000011872.2|UniProtKB=F6Z215 F6Z215 PTHR48416:SF1 CYTOCHROME C OXIDASE SUBUNIT 6C CYTOCHROME C OXIDASE SUBUNIT 6C CIOIN|Ensembl=ENSCING00000012852.2|UniProtKB=F6V5Q8 F6V5Q8 PTHR11731:SF202 PROTEASE FAMILY S9B,C DIPEPTIDYL-PEPTIDASE IV-RELATED DIPEPTIDYL PEPTIDASE FAMILY MEMBER 2 hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 serine protease#PC00203;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000008750.3|UniProtKB=F6T0K4 F6T0K4 LOC104265829 PTHR47958:SF150 ATP-DEPENDENT RNA HELICASE DBP3 ATP-DEPENDENT RNA HELICASE DDX17-RELATED catalytic activity, acting on RNA#GO:0140098;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;helicase activity#GO:0004386;ATP-dependent activity#GO:0140657;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;catalytic activity, acting on a nucleic acid#GO:0140640;mRNA binding#GO:0003729 cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA helicase#PC00032 CIOIN|Ensembl=ENSCING00000020685.1|UniProtKB=H2XL44 H2XL44 PTHR22594:SF5 ASPARTYL/LYSYL-TRNA SYNTHETASE ASPARTATE--TRNA LIGASE, MITOCHONDRIAL catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;ligase activity#GO:0016874;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;peptide biosynthetic process#GO:0043043;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 aminoacyl-tRNA synthetase#PC00047;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000004235.3|UniProtKB=F6YGC1 F6YGC1 PTHR24031:SF706 RNA HELICASE ATP-DEPENDENT RNA HELICASE DDX27-RELATED intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA helicase#PC00032 CIOIN|Ensembl=ENSCING00000001078.1|UniProtKB=F7B0G6 F7B0G6 PTHR24246:SF27 OLFACTORY RECEPTOR AND ADENOSINE RECEPTOR ADENOSINE RECEPTOR, ISOFORM A G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711 CIOIN|Ensembl=ENSCING00000007219.3|UniProtKB=F6W6Z9 F6W6Z9 LOC100177714 PTHR23049:SF71 MYOSIN REGULATORY LIGHT CHAIN 2 MYOSIN REGULATORY LIGHT CHAIN 1-RELATED cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;myosin binding#GO:0017022;binding#GO:0005488 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;myosin complex#GO:0016459;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 CIOIN|Ensembl=ENSCING00000001430.3|UniProtKB=H2XST8 H2XST8 PTHR23170:SF2 NY-REN-58 ANTIGEN CENTROSOMAL PROTEIN OF 83 KDA cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;cilium assembly#GO:0060271;organelle localization#GO:0051640;cell projection organization#GO:0030030;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;organelle organization#GO:0006996;centrosome localization#GO:0051642;establishment of localization in cell#GO:0051649;plasma membrane bounded cell projection assembly#GO:0120031;establishment of organelle localization#GO:0051656 microtubule organizing center#GO:0005815;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;centriole#GO:0005814;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;centrosome#GO:0005813;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;ciliary transition fiber#GO:0097539;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;cell projection#GO:0042995;cilium#GO:0005929 CIOIN|Ensembl=ENSCING00000018157.1|UniProtKB=H2XU92 H2XU92 PTHR22802:SF379 C-TYPE LECTIN SUPERFAMILY MEMBER CHONDROITIN SULFATE PROTEOGLYCAN 2 ISOFORM X1 membrane traffic protein#PC00150 CIOIN|Ensembl=ENSCING00000020241.1|UniProtKB=H2XS61 H2XS61 PTHR10117:SF54 TRANSIENT RECEPTOR POTENTIAL CHANNEL TRANSIENT RECEPTOR POTENTIAL-GAMMA PROTEIN calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;calcium channel activity#GO:0005262;small molecule binding#GO:0036094;binding#GO:0005488;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;anion binding#GO:0043168;ion binding#GO:0043167;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;alcohol binding#GO:0043178 inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;calcium ion transmembrane transport#GO:0070588;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;homeostatic process#GO:0042592;monoatomic cation homeostasis#GO:0055080;inorganic ion transmembrane transport#GO:0098660;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;cellular process#GO:0009987;regulation of cytosolic calcium ion concentration#GO:0051480;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;calcium ion transport#GO:0006816;monoatomic ion homeostasis#GO:0050801;localization#GO:0051179;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation transport#GO:0006812;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;cation channel complex#GO:0034703;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 Alzheimer disease-presenilin pathway#P00004>Capacitative calcium channels#P00124 CIOIN|Ensembl=ENSCING00000012259.2|UniProtKB=F6TP68 F6TP68 PTHR46348:SF1 DELETED IN LUNG AND ESOPHAGEAL CANCER PROTEIN 1 DELETED IN LUNG AND ESOPHAGEAL CANCER PROTEIN 1 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;organelle#GO:0043226;cilium#GO:0005929;plasma membrane bounded cell projection#GO:0120025;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000002087.3|UniProtKB=F7AA24 F7AA24 LOC100185081 PTHR12203:SF122 KDEL LYS-ASP-GLU-LEU CONTAINING - RELATED GLYCOSYL TRANSFERASE CAP10 DOMAIN-CONTAINING PROTEIN transferase activity#GO:0016740;glucosyltransferase activity#GO:0046527;catalytic activity#GO:0003824;glycosyltransferase activity#GO:0016757;hexosyltransferase activity#GO:0016758 cellular anatomical entity#GO:0110165;endomembrane system#GO:0012505 CIOIN|Ensembl=ENSCING00000020295.1|UniProtKB=H2XTT7 H2XTT7 PTHR22588:SF3 VWFA DOMAIN-CONTAINING PROTEIN VWFA DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000009523.3|UniProtKB=Q4H3N7 Q4H3N7 Ci-E12_E47 PTHR11793:SF13 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR PROTEIN DAUGHTERLESS sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;chromatin#GO:0000785;protein-DNA complex#GO:0032993;chromosome#GO:0005694;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 basic helix-loop-helix transcription factor#PC00055 CIOIN|Ensembl=ENSCING00000006127.3|UniProtKB=F6VR09 F6VR09 PTHR18919:SF153 ACETYL-COA C-ACYLTRANSFERASE TRIFUNCTIONAL ENZYME SUBUNIT BETA, MITOCHONDRIAL acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;acetyltransferase activity#GO:0016407;catalytic activity#GO:0003824 oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;lipid oxidation#GO:0034440;cellular metabolic process#GO:0044237;lipid catabolic process#GO:0016042;lipid modification#GO:0030258;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;fatty acid catabolic process#GO:0009062;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;fatty acid metabolic process#GO:0006631;small molecule catabolic process#GO:0044282;fatty acid beta-oxidation#GO:0006635;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;cellular lipid metabolic process#GO:0044255;cellular lipid catabolic process#GO:0044242;carboxylic acid metabolic process#GO:0019752;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;monocarboxylic acid catabolic process#GO:0072329 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 acyltransferase#PC00042 CIOIN|Ensembl=ENSCING00000004657.3|UniProtKB=F6RLS6 F6RLS6 PTHR11711:SF21 ADP RIBOSYLATION FACTOR-RELATED ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 6 carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167 cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;cilium assembly#GO:0060271;cell projection organization#GO:0030030;macromolecule localization#GO:0033036;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;cell projection assembly#GO:0030031;protein localization#GO:0008104;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;protein localization to cilium#GO:0061512;establishment of localization#GO:0051234;organelle organization#GO:0006996;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;protein localization to organelle#GO:0033365;plasma membrane bounded cell projection assembly#GO:0120031 axoneme#GO:0005930;cytoplasmic region#GO:0099568;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;plasma membrane bounded cell projection cytoplasm#GO:0032838;membrane-bounded organelle#GO:0043227;ciliary plasm#GO:0097014;cytoskeleton#GO:0005856;cell projection#GO:0042995;cilium#GO:0005929 G-protein#PC00020 CIOIN|Ensembl=ENSCING00000006574.3|UniProtKB=F6RHX2 F6RHX2 PTHR24253:SF55 TRANSMEMBRANE PROTEASE SERINE TRANSMEMBRANE PROTEASE SERINE 13 serine protease#PC00203;protease#PC00190 CIOIN|Ensembl=ENSCING00000024255.1|UniProtKB=H2XZS1 H2XZS1 LOC100187056 PTHR43975:SF2 ZGC:101858 EG:BACR7A4.14 PROTEIN-RELATED CIOIN|Ensembl=ENSCING00000024409.1|UniProtKB=F7AWV5 F7AWV5 PTHR16470:SF0 UBIQUITIN DOMAIN-CONTAINING PROTEIN UBFD1 UBIQUITIN DOMAIN-CONTAINING PROTEIN UBFD1 cell adhesion molecule binding#GO:0050839;nucleic acid binding#GO:0003676;protein binding#GO:0005515;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 CIOIN|Ensembl=ENSCING00000013899.2|UniProtKB=F6PWH2 F6PWH2 PTHR28630:SF29 FAMILY NOT NAMED PROSTAMIDE_PROSTAGLANDIN F SYNTHASE oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 organic acid biosynthetic process#GO:0016053;lipid metabolic process#GO:0006629;oxoacid metabolic process#GO:0043436;monocarboxylic acid biosynthetic process#GO:0072330;icosanoid metabolic process#GO:0006690;icosanoid biosynthetic process#GO:0046456;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;prostaglandin metabolic process#GO:0006693;fatty acid metabolic process#GO:0006631;unsaturated fatty acid metabolic process#GO:0033559;unsaturated fatty acid biosynthetic process#GO:0006636;small molecule biosynthetic process#GO:0044283;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281;fatty acid biosynthetic process#GO:0006633;organic substance metabolic process#GO:0071704 CIOIN|Ensembl=ENSCING00000013343.2|UniProtKB=A0A1W3JIP1 A0A1W3JIP1 LOC100178363 PTHR16040:SF7 AUSTRALIN, ISOFORM A-RELATED AUSTRALIN, ISOFORM A-RELATED CIOIN|Ensembl=ENSCING00000006858.3|UniProtKB=F6ZXA7 F6ZXA7 PTHR10801:SF2 24-DEHYDROCHOLESTEROL REDUCTASE FAD-BINDING PCMH-TYPE DOMAIN-CONTAINING PROTEIN oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor#GO:0016628 lipid metabolic process#GO:0006629;steroid metabolic process#GO:0008202;organic cyclic compound metabolic process#GO:1901360;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;primary metabolic process#GO:0044238 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;membrane#GO:0016020;intracellular anatomical structure#GO:0005622 reductase#PC00198;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000007063.3|UniProtKB=F6T3B5 F6T3B5 PTHR11937:SF387 ACTIN ACTIN-LIKE PROTEIN 53D intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 actin and actin related protein#PC00039;cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 Wnt signaling pathway#P00057>NFAT Target Genes#G01559;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>F-actin#P00858;Alzheimer disease-presenilin pathway#P00004>actin#P00114;Integrin signalling pathway#P00034>Actin#P00944;Huntington disease#P00029>Actin#P00807;Nicotinic acetylcholine receptor signaling pathway#P00044>Actin#P01090;Cadherin signaling pathway#P00012>F-actin#P00470;Cytoskeletal regulation by Rho GTPase#P00016>Actin#P00512 CIOIN|Ensembl=ENSCING00000006833.3|UniProtKB=F7AZT4 F7AZT4 LOC100185019 PTHR10778:SF10 SOLUTE CARRIER FAMILY 35 MEMBER B SOLUTE CARRIER FAMILY 35 MEMBER B1 carbohydrate derivative transmembrane transporter activity#GO:1901505;nucleobase-containing compound transmembrane transporter activity#GO:0015932;transmembrane transporter activity#GO:0022857;UDP-galactose transmembrane transporter activity#GO:0005459;nucleotide-sugar transmembrane transporter activity#GO:0005338;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215 localization#GO:0051179;organic substance transport#GO:0071702;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;organic anion transport#GO:0015711;nucleobase-containing compound transport#GO:0015931;nucleotide-sugar transmembrane transport#GO:0015780;transport#GO:0006810;nitrogen compound transport#GO:0071705;cellular process#GO:0009987;carbohydrate derivative transport#GO:1901264 bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;Golgi membrane#GO:0000139;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000002985.3|UniProtKB=F6QYD5 F6QYD5 PTHR24276:SF98 POLYSERASE-RELATED FI18310P1-RELATED serine protease#PC00203;protease#PC00190 CIOIN|Ensembl=ENSCING00000010630.3|UniProtKB=F6W5K3 F6W5K3 LOC101243220 PTHR10924:SF4 MAJOR FACILITATOR SUPERFAMILY PROTEIN-RELATED GH15861P tetrapyrrole binding#GO:0046906;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;binding#GO:0005488;organic cyclic compound binding#GO:0097159;heme binding#GO:0020037 localization#GO:0051179;organic substance transport#GO:0071702;metal ion transport#GO:0030001;establishment of localization#GO:0051234;transport#GO:0006810;monoatomic cation transport#GO:0006812;nitrogen compound transport#GO:0071705;iron ion transport#GO:0006826;transition metal ion transport#GO:0000041;monoatomic ion transport#GO:0006811 cellular anatomical entity#GO:0110165;membrane#GO:0016020 secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000020180.1|UniProtKB=H2XN19 H2XN19 PTHR15487:SF4 ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 2-BINDING PROTEIN ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 2-BINDING PROTEIN positive regulation of nitrogen compound metabolic process#GO:0051173;cellular localization#GO:0051641;regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;macromolecule localization#GO:0033036;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;protein localization to nucleus#GO:0034504;positive regulation of protein modification process#GO:0031401;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;positive regulation of metabolic process#GO:0009893;protein localization to organelle#GO:0033365;positive regulation of biological process#GO:0048518;positive regulation of protein phosphorylation#GO:0001934;positive regulation of phosphorylation#GO:0042327;regulation of peptidyl-tyrosine phosphorylation#GO:0050730;positive regulation of peptidyl-tyrosine phosphorylation#GO:0050731;positive regulation of phosphorus metabolic process#GO:0010562;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;protein localization#GO:0008104;positive regulation of cellular process#GO:0048522;localization#GO:0051179;regulation of primary metabolic process#GO:0080090;positive regulation of tyrosine phosphorylation of STAT protein#GO:0042531;positive regulation of protein metabolic process#GO:0051247;positive regulation of phosphate metabolic process#GO:0045937;cellular macromolecule localization#GO:0070727;regulation of macromolecule metabolic process#GO:0060255;maintenance of location#GO:0051235;regulation of cellular process#GO:0050794;regulation of protein phosphorylation#GO:0001932;maintenance of location in cell#GO:0051651;biological regulation#GO:0065007;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 envelope#GO:0031975;membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;mitochondrial envelope#GO:0005740;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;mitochondrial intermembrane space#GO:0005758;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000021859.1|UniProtKB=H2XWN4 H2XWN4 PTHR18460:SF3 TEL2 INTERACTING PROTEIN 1 TTI1 FAMILY MEMBER TELO2-INTERACTING PROTEIN 1 HOMOLOG cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000005724.3|UniProtKB=F6U2P7 F6U2P7 mnx PTHR24335:SF4 MOTOR NEURON AND PANCREAS HOMEOBOX PROTEIN EXTRA-EXTRA sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 cellular developmental process#GO:0048869;neurogenesis#GO:0022008;cell projection organization#GO:0030030;developmental process#GO:0032502;multicellular organism development#GO:0007275;cell morphogenesis#GO:0000902;cell projection morphogenesis#GO:0048858;cellular component organization#GO:0016043;nervous system development#GO:0007399;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;cellular anatomical entity morphogenesis#GO:0032989;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;cell differentiation#GO:0030154;system development#GO:0048731;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;neuron differentiation#GO:0030182;multicellular organismal process#GO:0032501;neuron projection morphogenesis#GO:0048812;neuron development#GO:0048666;central nervous system development#GO:0007417;plasma membrane bounded cell projection morphogenesis#GO:0120039;generation of neurons#GO:0048699 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 CIOIN|Ensembl=ENSCING00000005059.3|UniProtKB=F7A4X9 F7A4X9 PTHR10872:SF2 SH2B ADAPTER PROTEIN LNK, ISOFORM D molecular adaptor activity#GO:0060090;signaling adaptor activity#GO:0035591;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;protein tyrosine kinase binding#GO:1990782;signaling receptor complex adaptor activity#GO:0030159;receptor tyrosine kinase binding#GO:0030971;signaling receptor binding#GO:0005102;kinase binding#GO:0019900 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000013114.2|UniProtKB=F6WTI1 F6WTI1 PTHR10778:SF8 SOLUTE CARRIER FAMILY 35 MEMBER B ADENOSINE 3'-PHOSPHO 5'-PHOSPHOSULFATE TRANSPORTER 2 carbohydrate derivative transmembrane transporter activity#GO:1901505;purine nucleotide transmembrane transporter activity#GO:0015216;nucleobase-containing compound transmembrane transporter activity#GO:0015932;transmembrane transporter activity#GO:0022857;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215 localization#GO:0051179;organic substance transport#GO:0071702;organophosphate ester transport#GO:0015748;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;organic anion transport#GO:0015711;nucleobase-containing compound transport#GO:0015931;transport#GO:0006810;nitrogen compound transport#GO:0071705;cellular process#GO:0009987;carbohydrate derivative transport#GO:1901264 bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;Golgi membrane#GO:0000139;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000004991.2|UniProtKB=F6WM99 F6WM99 LOC100177778 PTHR12709:SF4 DNA-DIRECTED RNA POLYMERASE II, III DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB7 RNA metabolism protein#PC00031;DNA-directed RNA polymerase#PC00019 CIOIN|Ensembl=ENSCING00000025069.1|UniProtKB=H2XWZ3 H2XWZ3 PTHR10920:SF13 RIBOSOMAL RNA METHYLTRANSFERASE PRE-RRNA 2'-O-RIBOSE RNA METHYLTRANSFERASE FTSJ3 catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on RNA#GO:0140098;methyltransferase activity#GO:0008168;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;RNA methyltransferase activity#GO:0008173 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;RNA modification#GO:0009451;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;methylation#GO:0032259;macromolecule methylation#GO:0043414;nitrogen compound metabolic process#GO:0006807;RNA methylation#GO:0001510;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 RNA methyltransferase#PC00033 CIOIN|Ensembl=ENSCING00000002552.3|UniProtKB=F6X2H2 F6X2H2 PTHR19300:SF61 BETA-1,4-GALACTOSYLTRANSFERASE BETA-1,4-N-ACETYLGALACTOSAMINYLTRANSFERASE galactosyltransferase activity#GO:0008378;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 glycosylation#GO:0070085;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000008865.3|UniProtKB=F6R2U8 F6R2U8 PTHR18034:SF3 CELL CYCLE CONTROL PROTEIN CWF22-RELATED PRE-MRNA-SPLICING FACTOR CWC22 HOMOLOG nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704 ribonucleoprotein complex#GO:1990904;catalytic step 2 spliceosome#GO:0071013;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA processing factor#PC00147;RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000001083.3|UniProtKB=F7B040 F7B040 LOC100182715 PTHR24058:SF103 DUAL SPECIFICITY PROTEIN KINASE SERINE_THREONINE-PROTEIN KINASE PRP4 HOMOLOG transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;peptidyl-amino acid modification#GO:0018193;cellular process#GO:0009987;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;peptidyl-threonine phosphorylation#GO:0018107;nitrogen compound metabolic process#GO:0006807;peptidyl-serine modification#GO:0018209;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000002623.3|UniProtKB=F7B2S4 F7B2S4 LOC100175237 PTHR16021:SF13 MANSC DOMAIN CONTAINING PROTEIN 1 ETS DOMAIN-CONTAINING PROTEIN-RELATED CIOIN|Ensembl=ENSCING00000000534.3|UniProtKB=F6V1M6 F6V1M6 meta2 PTHR22906:SF43 PROPERDIN PROPERDIN CIOIN|Ensembl=ENSCING00000009200.3|UniProtKB=F6WNP9 F6WNP9 PTHR43355:SF2 FLAVIN REDUCTASE (NADPH) FLAVIN REDUCTASE (NADPH) oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 reductase#PC00198;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000024370.1|UniProtKB=H2XW64 H2XW64 PTHR10924:SF4 MAJOR FACILITATOR SUPERFAMILY PROTEIN-RELATED GH15861P tetrapyrrole binding#GO:0046906;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;binding#GO:0005488;organic cyclic compound binding#GO:0097159;heme binding#GO:0020037 localization#GO:0051179;organic substance transport#GO:0071702;metal ion transport#GO:0030001;establishment of localization#GO:0051234;transport#GO:0006810;monoatomic cation transport#GO:0006812;nitrogen compound transport#GO:0071705;iron ion transport#GO:0006826;transition metal ion transport#GO:0000041;monoatomic ion transport#GO:0006811 cellular anatomical entity#GO:0110165;membrane#GO:0016020 secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000007147.3|UniProtKB=F7BGS1 F7BGS1 LOC100184004 PTHR21230:SF89 VESICLE TRANSPORT V-SNARE PROTEIN VTI1-RELATED VESICLE TRANSPORT THROUGH INTERACTION WITH T-SNARES HOMOLOG 1B protein binding#GO:0005515;molecular adaptor activity#GO:0060090;SNAP receptor activity#GO:0005484;SNARE binding#GO:0000149;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674 vesicle fusion#GO:0006906;endosomal transport#GO:0016197;cellular localization#GO:0051641;intra-Golgi vesicle-mediated transport#GO:0006891;macroautophagy#GO:0016236;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;post-Golgi vesicle-mediated transport#GO:0006892;transport#GO:0006810;endomembrane system organization#GO:0010256;regulation of localization#GO:0032879;process utilizing autophagic mechanism#GO:0061919;regulation of biological process#GO:0050789;establishment of localization#GO:0051234;catabolic process#GO:0009056;vesicle organization#GO:0016050;regulation of protein localization#GO:0032880;organelle fusion#GO:0048284;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;Golgi organization#GO:0007030;vacuolar transport#GO:0007034;regulation of protein localization to membrane#GO:1905475;cellular metabolic process#GO:0044237;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;Golgi vesicle transport#GO:0048193;regulation of cellular localization#GO:0060341;cellular process#GO:0009987;cytosolic transport#GO:0016482;retrograde transport, endosome to Golgi#GO:0042147;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;membrane fusion#GO:0061025;Golgi to vacuole transport#GO:0006896;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;autophagy#GO:0006914 bounding membrane of organelle#GO:0098588;endosome#GO:0005768;COPII-coated ER to Golgi transport vesicle#GO:0030134;intracellular membrane-bounded organelle#GO:0043231;SNARE complex#GO:0031201;late endosome membrane#GO:0031902;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endosome membrane#GO:0010008;vesicle#GO:0031982;intracellular organelle#GO:0043229;transport vesicle membrane#GO:0030658;endoplasmic reticulum subcompartment#GO:0098827;cytoplasmic vesicle membrane#GO:0030659;late endosome#GO:0005770;membrane protein complex#GO:0098796;ER to Golgi transport vesicle membrane#GO:0012507;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;membrane#GO:0016020;coated vesicle#GO:0030135;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;coated vesicle membrane#GO:0030662;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;transport vesicle#GO:0030133;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 SNARE protein#PC00034 Adrenaline and noradrenaline biosynthesis#P00001>SNARE#P00072 CIOIN|Ensembl=ENSCING00000007397.3|UniProtKB=F6UKU4 F6UKU4 LOC100184902 PTHR13372:SF5 GEMININ GEMININ negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of cell cycle#GO:0045786;regulation of DNA metabolic process#GO:0051052;negative regulation of metabolic process#GO:0009892;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA metabolic process#GO:0051053;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000012987.2|UniProtKB=F6VUV2 F6VUV2 PTHR44436:SF1 F-BOX/WD REPEAT-CONTAINING PROTEIN 2 F-BOX_WD REPEAT-CONTAINING PROTEIN 2 CIOIN|Ensembl=ENSCING00000019779.1|UniProtKB=H2XU69 H2XU69 PTHR18934:SF113 ATP-DEPENDENT RNA HELICASE ATP-DEPENDENT RNA HELICASE TDRD9 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;helicase activity#GO:0004386;ATP-dependent activity#GO:0140657;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;catalytic activity, acting on a nucleic acid#GO:0140640 cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 RNA helicase#PC00032 CIOIN|Ensembl=ENSCING00000019924.1|UniProtKB=H2XN34 H2XN34 PTHR13132:SF29 ALPHA- 1,6 -FUCOSYLTRANSFERASE ALPHA-(1,6)-FUCOSYLTRANSFERASE transferase activity#GO:0016740;fucosyltransferase activity#GO:0008417;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein glycosylation#GO:0006486;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein N-linked glycosylation#GO:0006487;protein metabolic process#GO:0019538;glycosylation#GO:0070085;glycoprotein metabolic process#GO:0009100;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 glycosyltransferase#PC00111 Notch signaling pathway#P00045>Neurotic#P01115 CIOIN|Ensembl=ENSCING00000004214.3|UniProtKB=F6YGU8 F6YGU8 PTHR45727:SF2 NPC INTRACELLULAR CHOLESTEROL TRANSPORTER 1 NPC INTRACELLULAR CHOLESTEROL TRANSPORTER 1 lipid binding#GO:0008289;binding#GO:0005488;organic cyclic compound binding#GO:0097159;steroid binding#GO:0005496;sterol binding#GO:0032934 localization#GO:0051179;organic hydroxy compound transport#GO:0015850;organic substance transport#GO:0071702;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;sterol transport#GO:0015918;transport#GO:0006810;lipid localization#GO:0010876;lipid transport#GO:0006869 cellular anatomical entity#GO:0110165;membrane#GO:0016020 CIOIN|Ensembl=ENSCING00000013536.2|UniProtKB=F6YVQ1 F6YVQ1 LSM1 PTHR15588:SF8 LSM1 U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM1 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 negative regulation of gene expression#GO:0010629;regulation of catabolic process#GO:0009894;heterocycle catabolic process#GO:0046700;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;nucleobase-containing compound metabolic process#GO:0006139;RNA destabilization#GO:0050779;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;regulation of RNA stability#GO:0043487;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;positive regulation of mRNA catabolic process#GO:0061014;regulation of cellular process#GO:0050794;post-transcriptional regulation of gene expression#GO:0010608;positive regulation of catabolic process#GO:0009896;mRNA destabilization#GO:0061157;nucleobase-containing compound catabolic process#GO:0034655;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;regulation of mRNA stability#GO:0043488;RNA metabolic process#GO:0016070;positive regulation of cellular catabolic process#GO:0031331;cellular nitrogen compound catabolic process#GO:0044270;RNA decapping#GO:0110154;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;mRNA catabolic process#GO:0006402;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;regulation of gene expression#GO:0010468;organic substance catabolic process#GO:1901575;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;positive regulation of mRNA metabolic process#GO:1903313;heterocycle metabolic process#GO:0046483;negative regulation of biosynthetic process#GO:0009890;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;positive regulation of RNA metabolic process#GO:0051254 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;protein-containing complex#GO:0032991;P-body#GO:0000932;cellular anatomical entity#GO:0110165;organelle#GO:0043226;Sm-like protein family complex#GO:0120114;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464;intracellular anatomical structure#GO:0005622 RNA splicing factor#PC00148;RNA processing factor#PC00147 CIOIN|Ensembl=ENSCING00000006402.3|UniProtKB=F6QWS2 F6QWS2 LOC100184179 PTHR18929:SF210 PROTEIN DISULFIDE ISOMERASE PROTEIN DISULFIDE-ISOMERASE A4 isomerase activity#GO:0016853;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;protein disulfide isomerase activity#GO:0003756 cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;response to endoplasmic reticulum stress#GO:0034976;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;response to stress#GO:0006950;protein folding#GO:0006457;nitrogen compound metabolic process#GO:0006807;cellular response to stress#GO:0033554;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cell surface#GO:0009986;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chaperone#PC00072 CIOIN|Ensembl=ENSCING00000014262.2|UniProtKB=F6XAK3 F6XAK3 LOC100180243 PTHR45712:SF27 AGAP008170-PA LRRNT DOMAIN-CONTAINING PROTEIN extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 CIOIN|Ensembl=ENSCING00000000897.3|UniProtKB=F6U1H7 F6U1H7 LOC100176656 PTHR45721:SF11 LAMIN DM0-RELATED LAMIN DM0-RELATED FAS signaling pathway#P00020>Nuclear Lamin#P00616 CIOIN|Ensembl=ENSCING00000015663.2|UniProtKB=F6X515 F6X515 LOC100176891 PTHR21402:SF5 GAMETOCYTE SPECIFIC FACTOR 1-RELATED GAMETOCYTE SPECIFIC FACTOR 1 CIOIN|Ensembl=ENSCING00000020750.1|UniProtKB=H2XL16 H2XL16 LOC100177527 PTHR45710:SF26 C-TYPE LECTIN DOMAIN-CONTAINING PROTEIN 180 RH26557P defense/immunity protein#PC00090 CIOIN|Ensembl=ENSCING00000012525.2|UniProtKB=F7BDB7 F7BDB7 LOC100186663 PTHR11783:SF274 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4A1 sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824 cellular metabolic process#GO:0044237;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000023200.1|UniProtKB=H2XJY6 H2XJY6 PTHR12271:SF66 POLY A POLYMERASE CID PAP -RELATED TERMINAL URIDYLYLTRANSFERASE TAILOR catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on RNA#GO:0140098;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;RNA 3'-end processing#GO:0031123;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 nucleotidyltransferase#PC00174 CIOIN|Ensembl=ENSCING00000003250.3|UniProtKB=F6Z5A7 F6Z5A7 PTHR19444:SF13 UNC-93 RELATED PROTEIN UNC-93 HOMOLOG A membrane-bound signaling molecule#PC00152 CIOIN|Ensembl=ENSCING00000009231.3|UniProtKB=F6W1H2 F6W1H2 LOC100185196 PTHR19876:SF1 COATOMER COATOMER SUBUNIT ALPHA endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;intra-Golgi vesicle-mediated transport#GO:0006891;macromolecule localization#GO:0033036;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;coated vesicle#GO:0030135;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;vesicle coat#GO:0030120;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;Golgi-associated vesicle membrane#GO:0030660;protein-containing complex#GO:0032991;COPI vesicle coat#GO:0030126;endomembrane system#GO:0012505;membrane coat#GO:0030117;coated vesicle membrane#GO:0030662;COPI-coated vesicle#GO:0030137;Golgi-associated vesicle#GO:0005798;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;coated membrane#GO:0048475;cytoplasmic vesicle membrane#GO:0030659 vesicle coat protein#PC00235 CIOIN|Ensembl=ENSCING00000019989.1|UniProtKB=F7APQ3 F7APQ3 LOC100181917 PTHR23259:SF70 RIDDLE ACCESSORY GLAND PROTEIN ACP62F-RELATED protease inhibitor#PC00191;protein-binding activity modulator#PC00095 CIOIN|Ensembl=ENSCING00000004513.3|UniProtKB=F7ASY6 F7ASY6 LOC101243041 PTHR12866:SF2 UBIQUITIN-LIKE-CONJUGATING ENZYME ATG3 UBIQUITIN-LIKE-CONJUGATING ENZYME ATG3 ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;macroautophagy#GO:0016236;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;autophagy of mitochondrion#GO:0000422;cellular process#GO:0009987;organelle disassembly#GO:1903008;organelle assembly#GO:0070925;process utilizing autophagic mechanism#GO:0061919;cellular component organization or biogenesis#GO:0071840;vacuole organization#GO:0007033;cellular component disassembly#GO:0022411;organelle organization#GO:0006996;autophagosome assembly#GO:0000045;catabolic process#GO:0009056;mitochondrion organization#GO:0007005;autophagy#GO:0006914;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;phagophore assembly site#GO:0000407;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000013154.2|UniProtKB=F6YY07 F6YY07 PTHR13130:SF4 34 KDA TRANSCRIPTIONAL CO-ACTIVATOR-RELATED MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 27 transcription coactivator activity#GO:0003713;molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;protein-macromolecule adaptor activity#GO:0030674 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;mediator complex#GO:0016592;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transcription cofactor#PC00217 CIOIN|Ensembl=ENSCING00000004377.3|UniProtKB=F7AV37 F7AV37 PTHR13817:SF168 TITIN SUBFAMILY NOT NAMED sarcomere organization#GO:0045214;cellular component assembly#GO:0022607;cellular developmental process#GO:0048869;cellular component biogenesis#GO:0044085;cellular component assembly involved in morphogenesis#GO:0010927;muscle cell differentiation#GO:0042692;developmental process#GO:0032502;actomyosin structure organization#GO:0031032;cellular component organization#GO:0016043;myofibril assembly#GO:0030239;cellular process#GO:0009987;anatomical structure formation involved in morphogenesis#GO:0048646;cellular anatomical entity morphogenesis#GO:0032989;muscle cell development#GO:0055001;cell development#GO:0048468;organelle assembly#GO:0070925;muscle structure development#GO:0061061;cellular component organization or biogenesis#GO:0071840;striated muscle cell differentiation#GO:0051146;cell differentiation#GO:0030154;actin filament-based process#GO:0030029;anatomical structure morphogenesis#GO:0009653;organelle organization#GO:0006996;anatomical structure development#GO:0048856;supramolecular fiber organization#GO:0097435;striated muscle cell development#GO:0055002;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;non-membrane-bounded organelle assembly#GO:0140694 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;sarcomere#GO:0030017;A band#GO:0031672;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;organelle#GO:0043226;M band#GO:0031430;myofibril#GO:0030016;contractile fiber#GO:0043292;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 structural protein#PC00211 CIOIN|Ensembl=ENSCING00000000241.3|UniProtKB=F6TNQ8 F6TNQ8 PTHR23282:SF148 APICAL ENDOSOMAL GLYCOPROTEIN PRECURSOR. MAM DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000018080.1|UniProtKB=H2XS26 H2XS26 LOC100182515 PTHR21290:SF25 SPHINGOMYELIN SYNTHETASE SPHINGOMYELIN SYNTHASE-RELATED PROTEIN 1 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;membrane lipid biosynthetic process#GO:0046467;sphingolipid metabolic process#GO:0006665;primary metabolic process#GO:0044238;ceramide metabolic process#GO:0006672;amide biosynthetic process#GO:0043604;membrane lipid metabolic process#GO:0006643;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;ceramide biosynthetic process#GO:0046513;cellular lipid metabolic process#GO:0044255;amide metabolic process#GO:0043603;sphingolipid biosynthetic process#GO:0030148;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;Golgi membrane#GO:0000139;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 CIOIN|Ensembl=ENSCING00000004627.3|UniProtKB=F6PTZ3 F6PTZ3 PTHR11733:SF133 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED PHOSPHATE-REGULATING NEUTRAL ENDOPEPTIDASE PHEX hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;protein processing#GO:0016485;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 Endothelin signaling pathway#P00019>ECE1-3#P00585 CIOIN|Ensembl=ENSCING00000007512.3|UniProtKB=F6UJP3 F6UJP3 LOC100178191 PTHR33802:SF1 SI:CH211-161H7.5-RELATED XK-RELATED PROTEIN CIOIN|Ensembl=ENSCING00000019386.1|UniProtKB=H2XMD9 H2XMD9 LOC100185629 PTHR46786:SF1 ZINC FINGER MATRIN-TYPE PROTEIN 3 ZINC FINGER MATRIN-TYPE PROTEIN 3 RNA processing factor#PC00147 p53 pathway#P00059>PAG608#G04690 CIOIN|Ensembl=ENSCING00000014939.2|UniProtKB=F6PVL8 F6PVL8 PTHR11716:SF47 PHOSPHOLIPASE A2 FAMILY MEMBER PHOSPHOLIPASE A2-ALPHA phospholipase#PC00186 CIOIN|Ensembl=ENSCING00000002219.3|UniProtKB=F6Z726 F6Z726 LOC100183130 PTHR11932:SF174 CULLIN CULLIN-2 enzyme binding#GO:0019899;protein binding#GO:0005515;ubiquitin protein ligase binding#GO:0031625;binding#GO:0005488;ubiquitin-like protein ligase binding#GO:0044389 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;cullin-RING ubiquitin ligase complex#GO:0031461;transferase complex#GO:1990234 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 Parkinson disease#P00049>Cul-1#P01239 CIOIN|Ensembl=ENSCING00000023098.1|UniProtKB=H2XJH7 H2XJH7 PTHR19134:SF562 RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE PROTEIN-TYROSINE-PHOSPHATASE hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;protein tyrosine phosphatase activity#GO:0004725;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 protein phosphatase#PC00195;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000012244.2|UniProtKB=F7B554 F7B554 PTHR23349:SF72 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, TWIST HLH54F sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 basic helix-loop-helix transcription factor#PC00055 CIOIN|Ensembl=ENSCING00000012576.2|UniProtKB=F6YNJ1 F6YNJ1 PTHR11528:SF34 HEAT SHOCK PROTEIN 90 FAMILY MEMBER HEAT SHOCK PROTEIN 83 protein binding#GO:0005515;unfolded protein binding#GO:0051082;binding#GO:0005488 cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;response to heat#GO:0009408;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;regulation of protein stability#GO:0031647;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;protein stabilization#GO:0050821;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;response to stress#GO:0006950;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;protein folding#GO:0006457;cellular response to heat#GO:0034605;biological regulation#GO:0065007;response to temperature stimulus#GO:0009266;response to abiotic stimulus#GO:0009628;cellular response to stress#GO:0033554;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;perinuclear region of cytoplasm#GO:0048471;cytosol#GO:0005829;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 Hsp90 family chaperone#PC00028 CIOIN|Ensembl=ENSCING00000005702.3|UniProtKB=H2XQA8 H2XQA8 PTHR32289:SF1 PROTEIN FAM167A PROTEIN FAM167A-LIKE CIOIN|Ensembl=ENSCING00000007132.3|UniProtKB=F6S9G7 F6S9G7 PTHR24049:SF22 CRUMBS FAMILY MEMBER DROSOPHILA CRUMBS HOMOLOG cell adhesion molecule#PC00069 CIOIN|Ensembl=ENSCING00000005248.3|UniProtKB=F6XVD3 F6XVD3 LOC100176850 PTHR18034:SF4 CELL CYCLE CONTROL PROTEIN CWF22-RELATED NUCLEOLAR MIF4G DOMAIN-CONTAINING PROTEIN 1 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular component organization or biogenesis#GO:0071840;cellular component biogenesis#GO:0044085;ribosome biogenesis#GO:0042254;cellular process#GO:0009987;ribosomal small subunit biogenesis#GO:0042274;ribonucleoprotein complex biogenesis#GO:0022613 membrane-enclosed lumen#GO:0031974;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA processing factor#PC00147;RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000008855.3|UniProtKB=F6R3K6 F6R3K6 PTHR23253:SF78 EUKARYOTIC TRANSLATION INITIATION FACTOR 4 GAMMA EUKARYOTIC TRANSLATION INITIATION FACTOR 4G1, ISOFORM B-RELATED nucleic acid binding#GO:0003676;translation regulator activity#GO:0045182;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159;translation initiation factor activity#GO:0003743;mRNA binding#GO:0003729;translation regulator activity, nucleic acid binding#GO:0090079;translation factor activity, RNA binding#GO:0008135 cytoplasm#GO:0005737;intracellular protein-containing complex#GO:0140535;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622 translation initiation factor#PC00224;translation factor#PC00223;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000009766.3|UniProtKB=F6ZT40 F6ZT40 zf(rbz)-2 PTHR23193:SF23 NUCLEAR PORE COMPLEX PROTEIN NUP NUCLEAR PORE COMPLEX PROTEIN NUP153 signal sequence binding#GO:0005048;structural molecule activity#GO:0005198;structural constituent of nuclear pore#GO:0017056;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277 cellular localization#GO:0051641;macromolecule localization#GO:0033036;establishment of RNA localization#GO:0051236;transport#GO:0006810;protein localization to nucleus#GO:0034504;nucleic acid transport#GO:0050657;nitrogen compound transport#GO:0071705;establishment of protein localization to organelle#GO:0072594;cellular process#GO:0009987;establishment of protein localization#GO:0045184;RNA localization#GO:0006403;protein localization#GO:0008104;localization#GO:0051179;organic substance transport#GO:0071702;protein import into nucleus#GO:0006606;cellular macromolecule localization#GO:0070727;nuclear export#GO:0051168;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;RNA transport#GO:0050658;nucleobase-containing compound transport#GO:0015931;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;protein localization to organelle#GO:0033365;RNA export from nucleus#GO:0006405;nuclear transport#GO:0051169;import into nucleus#GO:0051170 envelope#GO:0031975;nuclear pore#GO:0005643;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear envelope#GO:0005635;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;organelle envelope#GO:0031967;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transporter#PC00227 CIOIN|Ensembl=ENSCING00000006177.3|UniProtKB=F7BKF4 F7BKF4 tlx PTHR45921:SF6 IP01054P C15 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;animal organ development#GO:0048513;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000013220.3|UniProtKB=F6V549 F6V549 PTHR13170:SF16 O-GLCNACASE PROTEIN O-GLCNACASE metabolite interconversion enzyme#PC00262;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000014905.2|UniProtKB=F6YR71 F6YR71 PTHR10516:SF443 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FK506-BINDING PROTEIN 59-RELATED chaperone#PC00072 TGF-beta signaling pathway#P00052>FKBP12#P01288 CIOIN|Ensembl=ENSCING00000023888.1|UniProtKB=H2XZ35 H2XZ35 PTHR22807:SF4 NOP2 YEAST -RELATED NOL1/NOP2/FMU SUN DOMAIN-CONTAINING 28S RRNA (CYTOSINE-C(5))-METHYLTRANSFERASE cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;RNA modification#GO:0009451;rRNA modification#GO:0000154;RNA processing#GO:0006396;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;ribosome biogenesis#GO:0042254;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;rRNA methylation#GO:0031167;nucleic acid metabolic process#GO:0090304;methylation#GO:0032259;macromolecule methylation#GO:0043414;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;rRNA base methylation#GO:0070475;RNA methylation#GO:0001510 intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA methyltransferase#PC00033 CIOIN|Ensembl=ENSCING00000018741.1|UniProtKB=H2XV74 H2XV74 PTHR11929:SF145 ALPHA- 1,3 -FUCOSYLTRANSFERASE ALPHA-(1,3)-FUCOSYLTRANSFERASE FUT-1 transferase activity#GO:0016740;fucosyltransferase activity#GO:0008417;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 glycosylation#GO:0070085;metabolic process#GO:0008152 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000002400.3|UniProtKB=F6QID5 F6QID5 PTHR11679:SF30 VESICLE PROTEIN SORTING-ASSOCIATED PROTEIN ROP syntaxin binding#GO:0019905;protein binding#GO:0005515;binding#GO:0005488;SNARE binding#GO:0000149 cellular localization#GO:0051641;organelle localization#GO:0051640;macromolecule localization#GO:0033036;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;exocytic process#GO:0140029;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;exocytosis#GO:0006887;establishment of localization#GO:0051234;secretion#GO:0046903;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;export from cell#GO:0140352;secretion by cell#GO:0032940 intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;secretory granule#GO:0030141;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 membrane trafficking regulatory protein#PC00151 CIOIN|Ensembl=ENSCING00000000705.3|UniProtKB=A0A1W2W422 A0A1W2W422 LOC100178593 PTHR12210:SF70 DULLARD PROTEIN PHOSPHATASE CTD NUCLEAR ENVELOPE PHOSPHATASE 1 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 protein phosphatase#PC00195;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000013094.2|UniProtKB=F6QIF4 F6QIF4 LOC100187276 PTHR12066:SF0 TELOMERASE REVERSE TRANSCRIPTASE TELOMERASE REVERSE TRANSCRIPTASE sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;transferase activity#GO:0016740;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;nucleotidyltransferase activity#GO:0016779;DNA binding#GO:0003677;telomeric DNA binding#GO:0042162;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on DNA#GO:0140097;DNA polymerase activity#GO:0034061 telomere maintenance via telomere lengthening#GO:0010833;cellular aromatic compound metabolic process#GO:0006725;telomere organization#GO:0032200;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;telomere maintenance#GO:0000723;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;telomere maintenance via telomerase#GO:0007004;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;DNA biosynthetic process#GO:0071897;chromosome organization#GO:0051276;organelle organization#GO:0006996;aromatic compound biosynthetic process#GO:0019438;DNA metabolic process#GO:0006259 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622 DNA metabolism protein#PC00009 CIOIN|Ensembl=ENSCING00000023743.1|UniProtKB=H2XTN7 H2XTN7 PTHR11827:SF103 SOLUTE CARRIER FAMILY 12, CATION COTRANSPORTERS SODIUM CHLORIDE COTRANSPORTER 69, ISOFORM E inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium ion transmembrane transporter activity#GO:0015079;sodium ion transmembrane transporter activity#GO:0015081;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;chloride transmembrane transporter activity#GO:0015108;monoatomic cation transmembrane transporter activity#GO:0008324;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;active monoatomic ion transmembrane transporter activity#GO:0022853;monoatomic anion transmembrane transporter activity#GO:0008509;inorganic anion transmembrane transporter activity#GO:0015103;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294 inorganic ion homeostasis#GO:0098771;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;sodium ion homeostasis#GO:0055078;chloride transmembrane transport#GO:1902476;inorganic ion transmembrane transport#GO:0098660;cellular homeostasis#GO:0019725;inorganic anion transmembrane transport#GO:0098661;import across plasma membrane#GO:0098739;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;monoatomic cation transport#GO:0006812;inorganic anion transport#GO:0015698;potassium ion transport#GO:0006813;regulation of anatomical structure size#GO:0090066;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;monoatomic anion transmembrane transport#GO:0098656;chloride transport#GO:0006821;homeostatic process#GO:0042592;monoatomic cation homeostasis#GO:0055080;cellular component organization#GO:0016043;cellular process#GO:0009987;chemical homeostasis#GO:0048878;regulation of cellular component size#GO:0032535;monoatomic ion homeostasis#GO:0050801;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;sodium ion transport#GO:0006814;regulation of cell size#GO:0008361;monoatomic ion transmembrane transport#GO:0034220;monoatomic anion transport#GO:0006820;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;import into cell#GO:0098657;sodium ion transmembrane transport#GO:0035725;potassium ion import across plasma membrane#GO:1990573 secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000006979.3|UniProtKB=F6SYJ4 F6SYJ4 PTHR23050:SF417 CALCIUM BINDING PROTEIN CALMODULIN-LIKE PROTEIN 6 cation binding#GO:0043169;small molecule binding#GO:0036094;molecular function regulator activity#GO:0098772;binding#GO:0005488;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;enzyme regulator activity#GO:0030234 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 calmodulin-related#PC00061 CIOIN|Ensembl=ENSCING00000007232.3|UniProtKB=F6VKW3 F6VKW3 PTHR12875:SF0 GOLGI TO ER TRAFFIC PROTEIN 4 HOMOLOG GOLGI TO ER TRAFFIC PROTEIN 4 HOMOLOG localization within membrane#GO:0051668;protein insertion into ER membrane#GO:0045048;cellular localization#GO:0051641;endoplasmic reticulum organization#GO:0007029;macromolecule localization#GO:0033036;membrane organization#GO:0061024;protein localization to membrane#GO:0072657;endomembrane system organization#GO:0010256;cellular component organization#GO:0016043;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of protein localization to membrane#GO:0090150;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;organelle organization#GO:0006996;protein localization to organelle#GO:0033365;protein insertion into membrane#GO:0051205 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000004008.3|UniProtKB=F6VXM8 F6VXM8 LOC100179750 PTHR22594:SF34 ASPARTYL/LYSYL-TRNA SYNTHETASE ASPARAGINE--TRNA LIGASE, MITOCHONDRIAL-RELATED cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;peptide biosynthetic process#GO:0043043;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 aminoacyl-tRNA synthetase#PC00047;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000005193.2|UniProtKB=F7B7C2 F7B7C2 LOC100186196 PTHR16076:SF8 CYTOSKELETON ASSOCIATED PROTEIN 2-RELATED CYTOSKELETON-ASSOCIATED PROTEIN 2 regulation of microtubule-based process#GO:0032886;negative regulation of protein depolymerization#GO:1901880;negative regulation of biological process#GO:0048519;regulation of organelle organization#GO:0033043;regulation of protein-containing complex disassembly#GO:0043244;regulation of cellular component organization#GO:0051128;regulation of microtubule polymerization or depolymerization#GO:0031110;negative regulation of supramolecular fiber organization#GO:1902904;regulation of supramolecular fiber organization#GO:1902903;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;regulation of protein depolymerization#GO:1901879;regulation of cellular process#GO:0050794;negative regulation of organelle organization#GO:0010639;regulation of microtubule cytoskeleton organization#GO:0070507;negative regulation of protein-containing complex disassembly#GO:0043242;biological regulation#GO:0065007;negative regulation of cellular component organization#GO:0051129;negative regulation of cellular process#GO:0048523;negative regulation of cytoskeleton organization#GO:0051494 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 CIOIN|Ensembl=ENSCING00000012686.2|UniProtKB=A0A1W2W8V2 A0A1W2W8V2 LOC100176678 PTHR12175:SF1 AD039 HT014 THIOREDOXIN FAMILY TRP26 PITH DOMAIN-CONTAINING PROTEIN 1 oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000005571.3|UniProtKB=F6U465 F6U465 PTHR23182:SF1 BREAKPOINT CLUSTER REGION PROTEIN BCR RHO GTPASE ACTIVATING PROTEIN AT 1A, ISOFORM E G-protein modulator#PC00022;protein-binding activity modulator#PC00095 CIOIN|Ensembl=ENSCING00000006828.3|UniProtKB=F7B006 F7B006 PTHR21580:SF60 SHIPPO-1-RELATED SPERM-TAIL PG-RICH REPEAT-CONTAINING PROTEIN 2 structural protein#PC00211 CIOIN|Ensembl=ENSCING00000004702.3|UniProtKB=F6QNF1 F6QNF1 PTHR45776:SF2 MIP04163P MIP04163P sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 basic helix-loop-helix transcription factor#PC00055 CIOIN|Ensembl=ENSCING00000014476.2|UniProtKB=F6Y9R7 F6Y9R7 PTHR12904:SF23 FAMILY NOT NAMED PROTEIN ZER-1 HOMOLOG CIOIN|Ensembl=ENSCING00000000166.3|UniProtKB=F6YYU4 F6YYU4 LOC100180111 PTHR19288:SF46 4-NITROPHENYLPHOSPHATASE-RELATED HALOACID DEHALOGENASE-LIKE HYDROLASE DOMAIN-CONTAINING PROTEIN 2 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 phosphatase#PC00181;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000016853.2|UniProtKB=H2XY52 H2XY52 PTHR24064:SF577 SOLUTE CARRIER FAMILY 22 MEMBER GH09241P secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000004534.3|UniProtKB=F7A934 F7A934 PTHR10827:SF98 RETICULOCALBIN 45 KDA CALCIUM-BINDING PROTEIN calmodulin-related#PC00061 Gonadotropin-releasing hormone receptor pathway#P06664>AMPK#P06830 CIOIN|Ensembl=ENSCING00000008363.3|UniProtKB=F7AJY7 F7AJY7 LOC100182594 PTHR24253:SF178 TRANSMEMBRANE PROTEASE SERINE TRANSMEMBRANE PROTEASE SERINE 12 serine protease#PC00203;protease#PC00190 CIOIN|Ensembl=ENSCING00000017690.2|UniProtKB=F6WC51 F6WC51 LOC101242487 PTHR28622:SF1 SMALL INTEGRAL MEMBRANE PROTEIN 7 SMALL INTEGRAL MEMBRANE PROTEIN 7 CIOIN|Ensembl=ENSCING00000006621.3|UniProtKB=F6QP54 F6QP54 LOC100179303 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE SSU-1 sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824 cellular metabolic process#GO:0044237;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000006567.2|UniProtKB=F6RID1 F6RID1 LOC100186171 PTHR24291:SF201 CYTOCHROME P450 FAMILY 4 CYTOCHROME P450, FAMILY 4, SUBFAMILY B, POLYPEPTIDE 7 oxygenase#PC00177;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000005834.3|UniProtKB=A0A1W3JRI0 A0A1W3JRI0 r27a PTHR10666:SF458 UBIQUITIN POLYUBIQUITIN-C nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159;ubiquitin-like protein ligase binding#GO:0044389;protein binding#GO:0005515;enzyme binding#GO:0019899;ubiquitin protein ligase binding#GO:0031625 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;protein modification by small protein conjugation#GO:0032446;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000009396.3|UniProtKB=F6UA80 F6UA80 LOC100180649 PTHR36978:SF4 P-LOOP CONTAINING NUCLEOTIDE TRIPHOSPHATE HYDROLASE P-LOOP CONTAINING NUCLEOSIDE TRIPHOSPHATE HYDROLASE PROTEIN metabolite interconversion enzyme#PC00262;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000005296.3|UniProtKB=F6TUU8 F6TUU8 PTHR21292:SF1 EXOCYST COMPLEX COMPONENT SEC6-RELATED EXOCYST COMPLEX COMPONENT 3 protein binding#GO:0005515;binding#GO:0005488;SNARE binding#GO:0000149 localization#GO:0051179;exocytosis#GO:0006887;establishment of localization#GO:0051234;secretion#GO:0046903;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;export from cell#GO:0140352;protein-containing complex localization#GO:0031503;secretion by cell#GO:0032940 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;vesicle tethering complex#GO:0099023;exocyst#GO:0000145;cell cortex#GO:0005938;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150 CIOIN|Ensembl=ENSCING00000019232.1|UniProtKB=H2XL36 H2XL36 LOC100178684 PTHR33442:SF1 TRANS-3-HYDROXY-L-PROLINE DEHYDRATASE TRANS-3-HYDROXY-L-PROLINE DEHYDRATASE dehydratase#PC00091;lyase#PC00144 CIOIN|Ensembl=ENSCING00000025112.1|UniProtKB=H2Y144 H2Y144 PTHR24416:SF620 TYROSINE-PROTEIN KINASE RECEPTOR TYROSINE-PROTEIN KINASE RECEPTOR TORSO signaling receptor activity#GO:0038023;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;molecular transducer activity#GO:0060089;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672;transmembrane signaling receptor activity#GO:0004888 signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;positive regulation of cellular metabolic process#GO:0031325;developmental process#GO:0032502;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;regulation of molecular function#GO:0065009;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;positive regulation of phosphorylation#GO:0042327;cellular response to stimulus#GO:0051716;positive regulation of catalytic activity#GO:0043085;multicellular organism development#GO:0007275;positive regulation of phosphorus metabolic process#GO:0010562;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphate metabolic process#GO:0045937;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;multicellular organismal process#GO:0032501;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 receptor complex#GO:0043235;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 CIOIN|Ensembl=ENSCING00000005209.3|UniProtKB=F6Z1D9 F6Z1D9 PTHR10660:SF2 PROTEASOME REGULATOR PA28 LD45860P peptidase activator activity#GO:0016504;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;peptidase regulator activity#GO:0061134;endopeptidase regulator activity#GO:0061135;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of protein metabolic process#GO:0051246;regulation of catabolic process#GO:0009894;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of molecular function#GO:0044093;regulation of protein catabolic process#GO:0042176;regulation of proteolysis involved in protein catabolic process#GO:1903050;regulation of catalytic activity#GO:0050790;positive regulation of proteolysis#GO:0045862;regulation of biological process#GO:0050789;positive regulation of metabolic process#GO:0009893;regulation of molecular function#GO:0065009;regulation of hydrolase activity#GO:0051336;regulation of G1/S transition of mitotic cell cycle#GO:2000045;positive regulation of peptidase activity#GO:0010952;positive regulation of biological process#GO:0048518;regulation of proteolysis#GO:0030162;regulation of mitotic cell cycle phase transition#GO:1901990;positive regulation of catalytic activity#GO:0043085;regulation of cell cycle phase transition#GO:1901987;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of hydrolase activity#GO:0051345;regulation of cell cycle process#GO:0010564;regulation of primary metabolic process#GO:0080090;regulation of proteasomal protein catabolic process#GO:0061136;positive regulation of protein metabolic process#GO:0051247;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;regulation of endopeptidase activity#GO:0052548;regulation of peptidase activity#GO:0052547;regulation of mitotic cell cycle#GO:0007346;positive regulation of endopeptidase activity#GO:0010950;regulation of cell cycle G1/S phase transition#GO:1902806;regulation of metabolic process#GO:0019222 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000021184.1|UniProtKB=H2Y1M8 H2Y1M8 LOC100176356 PTHR31305:SF2 SNARE-ASSOCIATED PROTEIN SNAPIN SNARE-ASSOCIATED PROTEIN SNAPIN protein binding#GO:0005515;SNARE binding#GO:0000149;binding#GO:0005488 lysosome organization#GO:0007040;cellular localization#GO:0051641;synaptic vesicle cycle#GO:0099504;organelle localization#GO:0051640;transport#GO:0006810;regulation of signaling#GO:0023051;regulation of secretion by cell#GO:1903530;regulation of localization#GO:0032879;endosome to lysosome transport#GO:0008333;regulation of neurotransmitter secretion#GO:0046928;lysosomal transport#GO:0007041;regulation of vesicle-mediated transport#GO:0060627;regulated exocytosis#GO:0045055;lysosome localization#GO:0032418;regulation of biological process#GO:0050789;vacuole organization#GO:0007033;regulation of transport#GO:0051049;chemical synaptic transmission#GO:0007268;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;regulation of secretion#GO:0051046;secretion#GO:0046903;neurotransmitter transport#GO:0006836;synaptic signaling#GO:0099536;signal release#GO:0023061;cell-cell signaling#GO:0007267;signaling#GO:0023052;synaptic vesicle exocytosis#GO:0016079;regulation of exocytosis#GO:0017157;secretion by cell#GO:0032940;neurotransmitter secretion#GO:0007269;regulation of cell communication#GO:0010646;vacuolar transport#GO:0007034;trans-synaptic signaling#GO:0099537;vesicle-mediated transport#GO:0016192;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;signal release from synapse#GO:0099643;exocytosis#GO:0006887;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;lytic vacuole organization#GO:0080171;export from cell#GO:0140352;vesicle-mediated transport in synapse#GO:0099003 presynapse#GO:0098793;synapse#GO:0045202;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;synaptic vesicle#GO:0008021;cell junction#GO:0030054;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;transport vesicle#GO:0030133;secretory vesicle#GO:0099503 CIOIN|Ensembl=ENSCING00000013701.2|UniProtKB=F6PRR0 F6PRR0 LOC100182085 PTHR35378:SF1 UNNAMED PRODUCT C2H2-TYPE DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000019237.1|UniProtKB=H2Y0M6 H2Y0M6 PTHR21184:SF6 MENORIN (DENDRITIC BRANCHING PROTEIN) CONSERVED PLASMA MEMBRANE PROTEIN extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 CIOIN|Ensembl=ENSCING00000021770.1|UniProtKB=H2XMP3 H2XMP3 PTHR11306:SF68 NIEMANN PICK TYPE C2 PROTEIN NPC2-RELATED NPC INTRACELLULAR CHOLESTEROL TRANSPORTER 2 lipid binding#GO:0008289;binding#GO:0005488;organic cyclic compound binding#GO:0097159;steroid binding#GO:0005496;sterol binding#GO:0032934 localization#GO:0051179;organic hydroxy compound transport#GO:0015850;organic substance transport#GO:0071702;establishment of localization#GO:0051234;macromolecule localization#GO:0033036;sterol transport#GO:0015918;transport#GO:0006810;lipid localization#GO:0010876;lipid transport#GO:0006869 CIOIN|Ensembl=ENSCING00000005381.3|UniProtKB=F7AVN1 F7AVN1 PTHR10949:SF0 LIPOYL SYNTHASE LIPOYL SYNTHASE, MITOCHONDRIAL Lipoate_biosynthesis#P02750>Lipoate synthase#P03004 CIOIN|Ensembl=ENSCING00000015920.2|UniProtKB=F6ZME6 F6ZME6 PTHR43658:SF8 SHORT-CHAIN DEHYDROGENASE/REDUCTASE 17-BETA-HYDROXYSTEROID DEHYDROGENASE 14-RELATED oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000018349.1|UniProtKB=H2XZY4 H2XZY4 PTHR24300:SF397 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 2U1 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;tetrapyrrole binding#GO:0046906;steroid hydroxylase activity#GO:0008395;oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497;heme binding#GO:0020037 response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;response to chemical#GO:0042221;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 oxygenase#PC00177;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000009378.3|UniProtKB=F6WXB6 F6WXB6 PTHR31102:SF1 FAMILY NOT NAMED CATION_H+ EXCHANGER DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000013452.2|UniProtKB=F6V2G1 F6V2G1 LOC100184050 PTHR46659:SF1 SERINE/THREONINE/TYROSINE-INTERACTING-LIKE PROTEIN 1 SERINE_THREONINE_TYROSINE-INTERACTING-LIKE PROTEIN 1 phosphatase binding#GO:0019902;phosphatase regulator activity#GO:0019208;binding#GO:0005488;molecular function regulator activity#GO:0098772;protein phosphatase regulator activity#GO:0019888;enzyme binding#GO:0019899;protein binding#GO:0005515;phosphatase inhibitor activity#GO:0019212;enzyme inhibitor activity#GO:0004857;protein phosphatase binding#GO:0019903;protein phosphatase inhibitor activity#GO:0004864;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234 positive regulation of apoptotic process#GO:0043065;regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;regulation of apoptotic process#GO:0042981;positive regulation of signal transduction#GO:0009967;regulation of organelle organization#GO:0033043;regulation of signaling#GO:0023051;regulation of cellular component organization#GO:0051128;regulation of apoptotic signaling pathway#GO:2001233;regulation of intracellular signal transduction#GO:1902531;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of programmed cell death#GO:0043068;regulation of cellular process#GO:0050794;regulation of cellular component biogenesis#GO:0044087;negative regulation of organelle organization#GO:0010639;regulation of organelle assembly#GO:1902115;regulation of signal transduction#GO:0009966;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of apoptotic signaling pathway#GO:2001235;negative regulation of cellular component organization#GO:0051129;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;negative regulation of cellular process#GO:0048523;regulation of intrinsic apoptotic signaling pathway#GO:2001242;regulation of programmed cell death#GO:0043067 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 Oxidative stress response#P00046>MKP5#P01131 CIOIN|Ensembl=ENSCING00000015963.2|UniProtKB=F6X3L7 F6X3L7 LOC100184342 PTHR12435:SF2 FAMILY NOT NAMED PROTEIN KTI12 HOMOLOG cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;tRNA metabolic process#GO:0006399;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;RNA modification#GO:0009451;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;tRNA modification#GO:0006400;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;tRNA wobble uridine modification#GO:0002098;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 CIOIN|Ensembl=ENSCING00000011261.2|UniProtKB=F6YTC2 F6YTC2 PTHR45942:SF5 PROTEIN PHOSPATASE 3 REGULATORY SUBUNIT B ALPHA ISOFORM TYPE 1 EF-HAND DOMAIN-CONTAINING PROTEIN phosphatase binding#GO:0019902;phosphatase regulator activity#GO:0019208;binding#GO:0005488;molecular function regulator activity#GO:0098772;protein phosphatase regulator activity#GO:0019888;protein binding#GO:0005515;enzyme binding#GO:0019899;enzyme regulator activity#GO:0030234 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;calcium-mediated signaling#GO:0019722;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;calcineurin-mediated signaling#GO:0097720;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein dephosphorylation#GO:0006470;cellular metabolic process#GO:0044237;cell communication#GO:0007154;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;dephosphorylation#GO:0016311;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;intracellular signal transduction#GO:0035556;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 protein serine/threonine phosphatase complex#GO:0008287;intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;catalytic complex#GO:1902494 CIOIN|Ensembl=ENSCING00000006187.3|UniProtKB=F7B1Y1 F7B1Y1 rs23 PTHR11652:SF14 30S RIBOSOMAL PROTEIN S12 FAMILY MEMBER SMALL RIBOSOMAL SUBUNIT PROTEIN US12 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic small ribosomal subunit#GO:0022627;cytosol#GO:0005829;small ribosomal subunit#GO:0015935;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000002065.3|UniProtKB=F6SU74 F6SU74 PTHR10117:SF54 TRANSIENT RECEPTOR POTENTIAL CHANNEL TRANSIENT RECEPTOR POTENTIAL-GAMMA PROTEIN calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;calcium channel activity#GO:0005262;small molecule binding#GO:0036094;binding#GO:0005488;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;anion binding#GO:0043168;ion binding#GO:0043167;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;alcohol binding#GO:0043178 inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;calcium ion transmembrane transport#GO:0070588;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;homeostatic process#GO:0042592;monoatomic cation homeostasis#GO:0055080;inorganic ion transmembrane transport#GO:0098660;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;cellular process#GO:0009987;regulation of cytosolic calcium ion concentration#GO:0051480;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;calcium ion transport#GO:0006816;monoatomic ion homeostasis#GO:0050801;localization#GO:0051179;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation transport#GO:0006812;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;cation channel complex#GO:0034703;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 Alzheimer disease-presenilin pathway#P00004>Capacitative calcium channels#P00124 CIOIN|Ensembl=ENSCING00000014866.2|UniProtKB=F7BFU9 F7BFU9 PTHR12461:SF53 HYPOXIA-INDUCIBLE FACTOR 1 ALPHA INHIBITOR-RELATED JMJC DOMAIN-CONTAINING PROTEIN protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000023767.1|UniProtKB=H2XRT0 H2XRT0 PTHR13105:SF7 MYELOID LEUKEMIA FACTOR MYELOID LEUKEMIA FACTOR intercellular signal molecule#PC00207 CIOIN|Ensembl=ENSCING00000007739.3|UniProtKB=F6Z0A0 F6Z0A0 PTHR11552:SF147 GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE CHOLINE DEHYDROGENASE, MITOCHONDRIAL oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000007065.3|UniProtKB=F6WWE1 F6WWE1 PTHR16146:SF46 INTELECTIN INTELECTIN-1A-RELATED CIOIN|Ensembl=ENSCING00000008192.3|UniProtKB=F6VDY1 F6VDY1 PTHR22603:SF66 CHOLINE/ETHANOALAMINE KINASE ETHANOLAMINE KINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301 lipid metabolic process#GO:0006629;phospholipid biosynthetic process#GO:0008654;organophosphate biosynthetic process#GO:0090407;glycerolipid biosynthetic process#GO:0045017;cellular metabolic process#GO:0044237;glycerophospholipid metabolic process#GO:0006650;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;phospholipid metabolic process#GO:0006644;lipid biosynthetic process#GO:0008610;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;primary metabolic process#GO:0044238;glycerolipid metabolic process#GO:0046486;glycerophospholipid biosynthetic process#GO:0046474;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 kinase#PC00137 CIOIN|Ensembl=ENSCING00000018519.1|UniProtKB=H2XSZ7 H2XSZ7 LOC100179411 PTHR34833:SF1 GENE, 17359-RELATED GENE, 17359-RELATED CIOIN|Ensembl=ENSCING00000004128.3|UniProtKB=F6V8N9 F6V8N9 zf(ubp_ring)-1 PTHR24007:SF7 BRCA1-ASSOCIATED PROTEIN BRCA1-ASSOCIATED PROTEIN transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein ubiquitination#GO:0016567;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;small GTPase-mediated signal transduction#GO:0007264;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;Ras protein signal transduction#GO:0007265;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cell communication#GO:0007154;cellular process#GO:0009987;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;nitrogen compound metabolic process#GO:0006807;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;intracellular signal transduction#GO:0035556;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;signaling#GO:0023052;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000000182.3|UniProtKB=F6WFL4 F6WFL4 PTHR11071:SF565 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE MOCA-CYP, ISOFORM A peptidyl-prolyl cis-trans isomerase activity#GO:0003755;isomerase activity#GO:0016853;catalytic activity, acting on a protein#GO:0140096;binding#GO:0005488;catalytic activity#GO:0003824;amide binding#GO:0033218;peptide binding#GO:0042277 macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein peptidyl-prolyl isomerization#GO:0000413;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;protein modification process#GO:0036211;gene expression#GO:0010467;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein folding#GO:0006457;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chaperone#PC00072 CIOIN|Ensembl=ENSCING00000002624.3|UniProtKB=F7B2T8 F7B2T8 PTHR11214:SF283 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE N-ACETYLLACTOSAMINIDE BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE 4-LIKE transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;protein O-linked glycosylation#GO:0006493;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 bounding membrane of organelle#GO:0098588;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;Golgi membrane#GO:0000139;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111 CIOIN|Ensembl=ENSCING00000004997.3|UniProtKB=F6TXZ8 F6TXZ8 PTHR12114:SF4 PARVIN GH23568P cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;actin binding#GO:0003779;binding#GO:0005488 cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actin filament-based process#GO:0030029;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987;organelle organization#GO:0006996 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 actin and actin related protein#PC00039;cytoskeletal protein#PC00085 CIOIN|Ensembl=ENSCING00000008749.3|UniProtKB=F6T0P8 F6T0P8 PTHR24251:SF42 OVOCHYMASE-RELATED CUB DOMAIN-CONTAINING PROTEIN serine protease#PC00203;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000003258.3|UniProtKB=F6Z531 F6Z531 LOC100178723 PTHR33690:SF3 DUF4605 DOMAIN-CONTAINING PROTEIN UBIQUITIN-LIKE DOMAIN-CONTAINING PROTEIN membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000023229.1|UniProtKB=H2XTD6 H2XTD6 LOC101243120 PTHR12701:SF20 BCR-ASSOCIATED PROTEIN, BAP ENDOPLASMIC RETICULUM TRANSMEMBRANE PROTEIN localization#GO:0051179;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;protein localization to endoplasmic reticulum#GO:0070972;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;transport#GO:0006810;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;protein localization to organelle#GO:0033365;intracellular transport#GO:0046907;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;protein localization#GO:0008104 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150 CIOIN|Ensembl=ENSCING00000004838.3|UniProtKB=F6TC09 F6TC09 PTHR11929:SF145 ALPHA- 1,3 -FUCOSYLTRANSFERASE ALPHA-(1,3)-FUCOSYLTRANSFERASE FUT-1 transferase activity#GO:0016740;fucosyltransferase activity#GO:0008417;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 glycosylation#GO:0070085;metabolic process#GO:0008152 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000007368.3|UniProtKB=F6VYZ5 F6VYZ5 PTHR12442:SF12 DYNEIN INTERMEDIATE CHAIN DYNEIN AXONEMAL INTERMEDIATE CHAIN 4 protein binding#GO:0005515;binding#GO:0005488 microtubule-based movement#GO:0007018;cellular process#GO:0009987;microtubule-based process#GO:0007017;cilium movement#GO:0003341 axoneme#GO:0005930;catalytic complex#GO:1902494;cytoplasmic region#GO:0099568;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;axonemal dynein complex#GO:0005858;microtubule associated complex#GO:0005875;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;plasma membrane bounded cell projection cytoplasm#GO:0032838;ciliary plasm#GO:0097014;dynein complex#GO:0030286;cell projection#GO:0042995;cytoskeleton#GO:0005856;cilium#GO:0005929 microtubule or microtubule-binding cytoskeletal protein#PC00157 CIOIN|Ensembl=ENSCING00000023719.1|UniProtKB=Q1RLE9 Q1RLE9 Ci-ZF(C2H2)-82 PTHR24393:SF15 ZINC FINGER PROTEIN IP01243P-RELATED DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 CIOIN|Ensembl=ENSCING00000003055.3|UniProtKB=F6PPJ1 F6PPJ1 PTHR24356:SF303 SERINE/THREONINE-PROTEIN KINASE ATYPICAL PROTEIN KINASE C transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular process#GO:0009987;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Alzheimer disease-amyloid secretase pathway#P00003>PKC#P00109;Endothelin signaling pathway#P00019>PKC#P00568;Angiogenesis#P00005>PKC#P00219;5HT2 type receptor mediated signaling pathway#P04374>PKC#P04420;EGF receptor signaling pathway#P00018>PKC#P00565;Histamine H1 receptor mediated signaling pathway#P04385>PKC#P04487;FGF signaling pathway#P00021>PKC#P00648;VEGF signaling pathway#P00056>PKC#P01425;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>PKC#P01074;Wnt signaling pathway#P00057>Protein Kinase C#P01458;Thyrotropin-releasing hormone receptor signaling pathway#P04394>PKC#P04583;Oxytocin receptor mediated signaling pathway#P04391>PKC#P04533 CIOIN|Ensembl=ENSCING00000009288.3|UniProtKB=Q4H3S8 Q4H3S8 Ci-CKN1 PTHR46202:SF1 DNA EXCISION REPAIR PROTEIN ERCC-8 DNA EXCISION REPAIR PROTEIN ERCC-8 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;macromolecule modification#GO:0043412;protein catabolic process#GO:0030163;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;post-translational protein modification#GO:0043687;nucleobase-containing compound metabolic process#GO:0006139;modification-dependent macromolecule catabolic process#GO:0043632;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;protein polyubiquitination#GO:0000209;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleotide-excision repair#GO:0006289;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;cellular response to stimulus#GO:0051716;protein ubiquitination#GO:0016567;modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259 ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cullin-RING ubiquitin ligase complex#GO:0031461;catalytic complex#GO:1902494;transferase complex#GO:1990234;nucleotide-excision repair complex#GO:0000109;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;Cul4-RING E3 ubiquitin ligase complex#GO:0080008;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 DNA metabolism protein#PC00009 CIOIN|Ensembl=ENSCING00000008990.3|UniProtKB=F6PKJ4 F6PKJ4 PTHR12412:SF2 CAP BINDING PROTEIN NUCLEAR CAP-BINDING PROTEIN SUBUNIT 1 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;RNA cap binding#GO:0000339;binding#GO:0005488;organic cyclic compound binding#GO:0097159 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;heterocycle catabolic process#GO:0046700;RNA metabolic process#GO:0016070;nucleobase-containing compound metabolic process#GO:0006139;cellular nitrogen compound catabolic process#GO:0044270;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;mRNA catabolic process#GO:0006402;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance catabolic process#GO:1901575;negative regulation of cellular process#GO:0048523;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;negative regulation of biosynthetic process#GO:0009890;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;nuclear-transcribed mRNA catabolic process#GO:0000956;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;nuclear-transcribed mRNA catabolic process, nonsense-mediated decay#GO:0000184;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;nucleobase-containing compound catabolic process#GO:0034655;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA splicing factor#PC00148;RNA processing factor#PC00147 CIOIN|Ensembl=ENSCING00000006190.3|UniProtKB=F7B1W3 F7B1W3 PTHR10954:SF7 RIBONUCLEASE H2 SUBUNIT A RIBONUCLEASE H2 SUBUNIT A catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a nucleic acid#GO:0140640;endonuclease activity#GO:0004519;RNA nuclease activity#GO:0004540;RNA endonuclease activity#GO:0004521 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle catabolic process#GO:0046700;RNA metabolic process#GO:0016070;mismatch repair#GO:0006298;nucleobase-containing compound metabolic process#GO:0006139;cellular nitrogen compound catabolic process#GO:0044270;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;organic substance catabolic process#GO:1901575;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;aromatic compound catabolic process#GO:0019439;organic cyclic compound catabolic process#GO:1901361;nucleobase-containing compound catabolic process#GO:0034655;cellular response to stress#GO:0033554;DNA replication#GO:0006260;DNA metabolic process#GO:0006259 intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;catalytic complex#GO:1902494 endoribonuclease#PC00094;RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000006390.3|UniProtKB=F6RJU6 F6RJU6 PTHR12129:SF15 HEPARAN SULFATE 2-O-SULFOTRANSFERASE URONYL 2-SULFOTRANSFERASE transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000002912.3|UniProtKB=F6SCG1 F6SCG1 PTHR31219:SF2 CHROMOSOME 28 C12ORF29 HOMOLOG RNA LIGASE 1 CIOIN|Ensembl=ENSCING00000005822.3|UniProtKB=Q5VHU3 Q5VHU3 amt-2 PTHR11730:SF6 AMMONIUM TRANSPORTER AMMONIUM TRANSPORTER localization#GO:0051179;inorganic ion homeostasis#GO:0098771;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;nitrogen compound transport#GO:0071705;homeostatic process#GO:0042592;inorganic ion transmembrane transport#GO:0098660;chemical homeostasis#GO:0048878;cellular process#GO:0009987 primary active transporter#PC00068;transporter#PC00227 CIOIN|Ensembl=ENSCING00000003295.3|UniProtKB=F6WMS1 F6WMS1 PTHR11863:SF226 STEROL DESATURASE FATTY ACID HYDROXYLASE DOMAIN-CONTAINING PROTEIN 2-RELATED oxidase#PC00175;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000024191.1|UniProtKB=H2XZN6 H2XZN6 PTHR10704:SF44 CARBOHYDRATE SULFOTRANSFERASE LD35051P-RELATED sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824 cellular metabolic process#GO:0044237;amino sugar metabolic process#GO:0006040;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000001841.3|UniProtKB=F6TTQ6 F6TTQ6 LOC100175363 PTHR19282:SF519 TETRASPANIN TETRASPANIN cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000003743.3|UniProtKB=F6TIU3 F6TIU3 PTHR19877:SF1 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT I EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT I nucleic acid binding#GO:0003676;RNA binding#GO:0003723;translation regulator activity#GO:0045182;binding#GO:0005488;organic cyclic compound binding#GO:0097159;translation initiation factor activity#GO:0003743;translation regulator activity, nucleic acid binding#GO:0090079;translation factor activity, RNA binding#GO:0008135 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cytoplasmic translation#GO:0002181;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cytoplasmic translational initiation#GO:0002183;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;translational initiation#GO:0006413;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;eukaryotic translation initiation factor 3 complex#GO:0005852;intracellular anatomical structure#GO:0005622 translation initiation factor#PC00224;translation factor#PC00223 CIOIN|Ensembl=ENSCING00000004298.3|UniProtKB=Q68A30 Q68A30 Ci-Mech2 PTHR35259:SF2 BOMBESIN RECEPTOR-ACTIVATED PROTEIN C6ORF89 SUBFAMILY NOT NAMED CIOIN|Ensembl=ENSCING00000008618.3|UniProtKB=F6T283 F6T283 PTHR12085:SF3 SERINE/THREONINE-PROTEIN PHOSPHATASE 2A REGULATORY SUBUNIT B'' SUBUNIT GAMMA SERINE_THREONINE-PROTEIN PHOSPHATASE 2A REGULATORY SUBUNIT B'' SUBUNIT GAMMA cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;cortical cytoskeleton organization#GO:0030865;microtubule cytoskeleton organization#GO:0000226;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;spindle#GO:0005819;intracellular anatomical structure#GO:0005622 protein phosphatase#PC00195;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000022682.1|UniProtKB=H2XR85 H2XR85 PTHR24006:SF702 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 47 cysteine-type peptidase activity#GO:0008234;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;cysteine-type deubiquitinase activity#GO:0004843 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;protein modification by small protein removal#GO:0070646;protein deubiquitination#GO:0016579;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;post-translational protein modification#GO:0043687;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cysteine protease#PC00081;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000006838.3|UniProtKB=A0A1W2WHR9 A0A1W2WHR9 LOC100185576 PTHR24073:SF285 DRAB5-RELATED RAS-RELATED PROTEIN RAB-18 GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824 localization#GO:0051179;organic substance transport#GO:0071702;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;transport#GO:0006810;protein transport#GO:0015031;nitrogen compound transport#GO:0071705;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 small GTPase#PC00208;G-protein#PC00020 CIOIN|Ensembl=ENSCING00000009116.3|UniProtKB=F6SQ23 F6SQ23 LOC100185183 PTHR16007:SF15 EPIDIDYMAL MEMBRANE PROTEIN E9-RELATED TRANSMEMBRANE PROTEIN 45B CIOIN|Ensembl=ENSCING00000004789.3|UniProtKB=F6RIY5 F6RIY5 PTHR24031:SF292 RNA HELICASE ATP-DEPENDENT RNA HELICASE DDX54 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA helicase#PC00032 CIOIN|Ensembl=ENSCING00000005420.3|UniProtKB=F6Z910 F6Z910 ppan PTHR12661:SF5 PETER PAN-RELATED SUPPRESSOR OF SWI4 1 HOMOLOG nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159;rRNA binding#GO:0019843 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;cellular process#GO:0009987;ribosomal large subunit biogenesis#GO:0042273;organelle assembly#GO:0070925;protein-RNA complex assembly#GO:0022618;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;organelle organization#GO:0006996;ribosomal large subunit assembly#GO:0000027;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;protein-RNA complex organization#GO:0071826;non-membrane-bounded organelle assembly#GO:0140694 ribonucleoprotein complex#GO:1990904;preribosome#GO:0030684;preribosome, large subunit precursor#GO:0030687;protein-containing complex#GO:0032991 RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000001499.3|UniProtKB=F6SW98 F6SW98 PTHR13132:SF29 ALPHA- 1,6 -FUCOSYLTRANSFERASE ALPHA-(1,6)-FUCOSYLTRANSFERASE transferase activity#GO:0016740;fucosyltransferase activity#GO:0008417;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein glycosylation#GO:0006486;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein N-linked glycosylation#GO:0006487;protein metabolic process#GO:0019538;glycosylation#GO:0070085;glycoprotein metabolic process#GO:0009100;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 glycosyltransferase#PC00111 Notch signaling pathway#P00045>Neurotic#P01115 CIOIN|Ensembl=ENSCING00000012636.2|UniProtKB=H2XR86 H2XR86 PTHR24412:SF172 KELCH PROTEIN KELCH-LIKE PROTEIN 10 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000001680.3|UniProtKB=F6UK45 F6UK45 PTHR24115:SF9 KINESIN-RELATED KINESIN HEAVY CHAIN cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;plus-end-directed microtubule motor activity#GO:0008574;binding#GO:0005488;catalytic activity#GO:0003824;cytoskeletal motor activity#GO:0003774;microtubule binding#GO:0008017;ribonucleoside triphosphate phosphatase activity#GO:0017111;ATP hydrolysis activity#GO:0016887;pyrophosphatase activity#GO:0016462;microtubule motor activity#GO:0003777;ATP-dependent activity#GO:0140657;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817 localization#GO:0051179;cellular localization#GO:0051641;microtubule-based process#GO:0007017;establishment of localization#GO:0051234;transport#GO:0006810;cytoskeleton-dependent intracellular transport#GO:0030705;microtubule-based movement#GO:0007018;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;microtubule associated complex#GO:0005875;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 CIOIN|Ensembl=ENSCING00000020468.1|UniProtKB=F6PLI6 F6PLI6 PTHR36978:SF4 P-LOOP CONTAINING NUCLEOTIDE TRIPHOSPHATE HYDROLASE P-LOOP CONTAINING NUCLEOSIDE TRIPHOSPHATE HYDROLASE PROTEIN metabolite interconversion enzyme#PC00262;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000015051.2|UniProtKB=F6S8H0 F6S8H0 LOC101243169 PTHR28578:SF2 MITOTIC-SPINDLE ORGANIZING PROTEIN 2A-RELATED MITOTIC-SPINDLE ORGANIZING PROTEIN 2 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;spindle#GO:0005819;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;centrosome#GO:0005813 CIOIN|Ensembl=ENSCING00000008616.3|UniProtKB=F6T2A6 F6T2A6 PTHR23050:SF518 CALCIUM BINDING PROTEIN AT16150P-RELATED cation binding#GO:0043169;small molecule binding#GO:0036094;molecular function regulator activity#GO:0098772;binding#GO:0005488;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;enzyme regulator activity#GO:0030234 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 calmodulin-related#PC00061 B cell activation#P00010>Calmodulin#P00375;Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Calmodulin#P00755;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Phosphorylase b kinase#P00716;T cell activation#P00053>Calmodulin#P01305 CIOIN|Ensembl=ENSCING00000018750.1|UniProtKB=H2Y2D6 H2Y2D6 PTHR10353:SF36 GLYCOSYL HYDROLASE LP05116P hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;glucosidase activity#GO:0015926;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 glycosidase#PC00110;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000007631.3|UniProtKB=F6XNG1 F6XNG1 PTHR13325:SF3 PROTEASE M50 MEMBRANE-BOUND TRANSCRIPTION FACTOR SITE 2 PROTEASE MEMBRANE-BOUND TRANSCRIPTION FACTOR SITE-2 PROTEASE hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 membrane protein proteolysis#GO:0033619;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 metalloprotease#PC00153;protease#PC00190 CIOIN|Ensembl=ENSCING00000008301.3|UniProtKB=F6QC31 F6QC31 PTHR24300:SF397 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 2U1 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;tetrapyrrole binding#GO:0046906;steroid hydroxylase activity#GO:0008395;oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497;heme binding#GO:0020037 response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;response to chemical#GO:0042221;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 oxygenase#PC00177;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000013570.2|UniProtKB=F6YBG1 F6YBG1 PTHR35678:SF1 PROTEIN STPG4 PROTEIN STPG4 protein binding#GO:0005515;protein-containing complex binding#GO:0044877;histone binding#GO:0042393;binding#GO:0005488;chromatin binding#GO:0003682 positive regulation of nitrogen compound metabolic process#GO:0051173;protein-DNA complex organization#GO:0071824;regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA metabolic process#GO:0051052;positive regulation of cellular metabolic process#GO:0031325;cellular component organization#GO:0016043;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;epigenetic regulation of gene expression#GO:0040029;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;positive regulation of metabolic process#GO:0009893;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;protein-containing complex organization#GO:0043933;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;chromatin remodeling#GO:0006338;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000001701.3|UniProtKB=H2XV50 H2XV50 PTHR11771:SF153 LIPOXYGENASE LIPOXYGENASE DOMAIN-CONTAINING PROTEIN oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;dioxygenase activity#GO:0051213 lipid metabolic process#GO:0006629;lipid oxidation#GO:0034440;cellular metabolic process#GO:0044237;lipid modification#GO:0030258;cellular lipid metabolic process#GO:0044255;cellular process#GO:0009987;metabolic process#GO:0008152;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704 oxygenase#PC00177;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000007184.3|UniProtKB=F6YSD1 F6YSD1 PTHR11819:SF195 SOLUTE CARRIER FAMILY 5 SODIUM_GLUCOSE COTRANSPORTER 4 inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;carbohydrate transmembrane transporter activity#GO:0015144;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;sugar transmembrane transporter activity#GO:0051119;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;active transmembrane transporter activity#GO:0022804;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;active monoatomic ion transmembrane transporter activity#GO:0022853;monoatomic ion transmembrane transporter activity#GO:0015075;inorganic cation transmembrane transporter activity#GO:0022890;solute:monoatomic cation symporter activity#GO:0015294 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000002507.3|UniProtKB=F6YER6 F6YER6 PTHR46780:SF9 PROTEIN EVA-1 D-GALACTOSIDE_L-RHAMNOSE BINDING SUEL LECTIN PROTEIN CIOIN|Ensembl=ENSCING00000006688.3|UniProtKB=F7ASD2 F7ASD2 PTHR43539:SF23 FLAVIN-BINDING MONOOXYGENASE-LIKE PROTEIN (AFU_ORTHOLOGUE AFUA_4G09220) FAD-DEPENDENT OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN 2 nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;flavin adenine dinucleotide binding#GO:0050660;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;anion binding#GO:0043168;oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497 response to organic substance#GO:0010033;macromolecule catabolic process#GO:0009057;cellular response to stimulus#GO:0051716;response to endoplasmic reticulum stress#GO:0034976;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;response to organonitrogen compound#GO:0010243;ERAD pathway#GO:0036503;cellular process#GO:0009987;primary metabolic process#GO:0044238;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;cellular response to stress#GO:0033554;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;endoplasmic reticulum lumen#GO:0005788;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 oxygenase#PC00177;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000024834.1|UniProtKB=H2Y1J9 H2Y1J9 PTHR24412:SF172 KELCH PROTEIN KELCH-LIKE PROTEIN 10 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000006620.3|UniProtKB=B5UA19 B5UA19 Ci-VP-R PTHR24241:SF161 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN signaling receptor activity#GO:0038023;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled peptide receptor activity#GO:0008528;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cellular response to endogenous stimulus#GO:0071495;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to endogenous stimulus#GO:0009719;response to hormone#GO:0009725;cellular response to hormone stimulus#GO:0032870;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 CIOIN|Ensembl=ENSCING00000015409.2|UniProtKB=A0A1W5BGX7 A0A1W5BGX7 LOC100181003 PTHR28624:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 51 MITOCHONDRIAL POTASSIUM CHANNEL CIOIN|Ensembl=ENSCING00000013152.2|UniProtKB=F6YY79 F6YY79 PTHR18849:SF0 LEUCINE RICH REPEAT PROTEIN CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 410-RELATED CIOIN|Ensembl=ENSCING00000002608.3|UniProtKB=F7B349 F7B349 PTHR19316:SF35 PROTEIN FOLDING REGULATOR NUCLEOTIDE EXCHANGE FACTOR SIL1 nucleoside phosphate binding#GO:1901265;nucleotide binding#GO:0000166;heterocyclic compound binding#GO:1901363;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;molecular function regulator activity#GO:0098772 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000025204.1|UniProtKB=Q8HIN5 Q8HIN5 cytb PTHR19271:SF16 CYTOCHROME B CYTOCHROME B cellular anatomical entity#GO:0110165;membrane#GO:0016020 FAS signaling pathway#P00020>CytochromeC#P00620;Huntington disease#P00029>Cytochrome c#P00785 CIOIN|Ensembl=ENSCING00000015233.2|UniProtKB=F6VBN4 F6VBN4 PTHR48017:SF48 OS05G0424000 PROTEIN-RELATED MAHOGANY CIOIN|Ensembl=ENSCING00000007733.3|UniProtKB=F6Z092 F6Z092 LOC100177115 PTHR10514:SF27 ANGIOTENSIN-CONVERTING ENZYME ANGIOTENSIN-CONVERTING ENZYME metalloprotease#PC00153;protease#PC00190 CIOIN|Ensembl=ENSCING00000000423.3|UniProtKB=F7BKD9 F7BKD9 PTHR43330:SF8 METHIONINE AMINOPEPTIDASE METHIONINE AMINOPEPTIDASE 1D, MITOCHONDRIAL metalloexopeptidase activity#GO:0008235;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;aminopeptidase activity#GO:0004177;exopeptidase activity#GO:0008238;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;metalloaminopeptidase activity#GO:0070006 metalloprotease#PC00153;protease#PC00190 CIOIN|Ensembl=ENSCING00000023493.1|UniProtKB=H2Y2V4 H2Y2V4 PTHR44329:SF288 SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 20 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000011948.2|UniProtKB=F6VA08 F6VA08 PTHR42923:SF3 PROTOPORPHYRINOGEN OXIDASE PROTOPORPHYRINOGEN OXIDASE oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 oxidase#PC00175;oxidoreductase#PC00176 Heme biosynthesis#P02746>Protoporphyrinogen oxidase#P02976 CIOIN|Ensembl=ENSCING00000014720.2|UniProtKB=F6ZBK7 F6ZBK7 PTHR10662:SF22 NUCLEAR RNA EXPORT FACTOR NUCLEAR RNA EXPORT FACTOR 1 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 poly(A)+ mRNA export from nucleus#GO:0016973;mRNA export from nucleus#GO:0006406;cellular localization#GO:0051641;macromolecule biosynthetic process#GO:0009059;macromolecule localization#GO:0033036;establishment of RNA localization#GO:0051236;macromolecule metabolic process#GO:0043170;transport#GO:0006810;nucleic acid transport#GO:0050657;nitrogen compound transport#GO:0071705;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;mRNA transport#GO:0051028;RNA localization#GO:0006403;localization#GO:0051179;organic substance transport#GO:0071702;nuclear export#GO:0051168;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;RNA transport#GO:0050658;nucleobase-containing compound transport#GO:0015931;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;nuclear transport#GO:0051169;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000001031.3|UniProtKB=F6VEV6 F6VEV6 hox10 PTHR45874:SF4 HOMEOBOX PROTEIN ABDOMINAL-B HOMEOBOX PROTEIN ABDOMINAL-B sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 CIOIN|Ensembl=ENSCING00000024802.1|UniProtKB=H2XMR6 H2XMR6 PTHR11537:SF113 VOLTAGE-GATED POTASSIUM CHANNEL POTASSIUM VOLTAGE-GATED CHANNEL PROTEIN SHAKER monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;delayed rectifier potassium channel activity#GO:0005251;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated potassium channel activity#GO:0005249;transporter activity#GO:0005215;channel activity#GO:0015267;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;regulation of membrane potential#GO:0042391;action potential#GO:0001508;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;localization#GO:0051179;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;monoatomic cation transport#GO:0006812;potassium ion transmembrane transport#GO:0071805;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;potassium ion transport#GO:0006813 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;voltage-gated potassium channel complex#GO:0008076;cation channel complex#GO:0034703;plasma membrane#GO:0005886 transporter#PC00227;voltage-gated ion channel#PC00241 CIOIN|Ensembl=ENSCING00000005001.3|UniProtKB=F6WLC1 F6WLC1 PTHR24366:SF161 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS TIR DOMAIN-CONTAINING PROTEIN cell adhesion molecule#PC00069;immunoglobulin superfamily cell adhesion molecule#PC00125 CIOIN|Ensembl=ENSCING00000018631.1|UniProtKB=H2XWL2 H2XWL2 LOC100186699 PTHR13531:SF0 GEO07735P1-RELATED-RELATED GEO07735P1-RELATED organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;non-motile cilium assembly#GO:1905515;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cell projection organization#GO:0030030;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cilium#GO:0005929;ciliary transition zone#GO:0035869 CIOIN|Ensembl=ENSCING00000001643.3|UniProtKB=F6YJB7 F6YJB7 LOC100179498 PTHR10142:SF0 DNA REPAIR PROTEIN COMPLEMENTING XP-A CELLS DNA REPAIR PROTEIN COMPLEMENTING XP-A CELLS damaged DNA binding#GO:0003684;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;nucleobase-containing compound metabolic process#GO:0006139;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;interstrand cross-link repair#GO:0036297;nitrogen compound metabolic process#GO:0006807;response to radiation#GO:0009314;response to abiotic stimulus#GO:0009628;cellular response to light stimulus#GO:0071482;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleotide-excision repair#GO:0006289;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;response to light stimulus#GO:0009416;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;base-excision repair#GO:0006284;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;response to UV#GO:0009411;chromosome organization#GO:0051276;organelle organization#GO:0006996;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleotide-excision repair complex#GO:0000109;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 damaged DNA-binding protein#PC00086;DNA metabolism protein#PC00009 CIOIN|Ensembl=ENSCING00000003418.3|UniProtKB=F6XLF0 F6XLF0 PTHR24355:SF28 G PROTEIN-COUPLED RECEPTOR KINASE/RIBOSOMAL PROTEIN S6 KINASE G PROTEIN-COUPLED RECEPTOR KINASE 2 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of cell communication#GO:0010646;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;regulation of signaling#GO:0023051;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>GPRK#P00840 CIOIN|Ensembl=ENSCING00000005246.3|UniProtKB=F6XUY3 F6XUY3 LOC100181359 PTHR43157:SF31 PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN-RELATED PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000003861.3|UniProtKB=F6Y4V4 F6Y4V4 LOC100175624 PTHR24068:SF74 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2-17 KDA ubiquitin-like protein conjugating enzyme activity#GO:0061650;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin conjugating enzyme activity#GO:0061631;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein polyubiquitination#GO:0000209;post-translational protein modification#GO:0043687;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 Ubiquitin proteasome pathway#P00060>E2#P01491 CIOIN|Ensembl=ENSCING00000014443.2|UniProtKB=F6YU16 F6YU16 LOC100185697 PTHR37153:SF1 CHROMOSOME 19 C19ORF81 HOMOLOG HYPOTHETICAL LOC292874 CIOIN|Ensembl=ENSCING00000018180.1|UniProtKB=H2XV19 H2XV19 PTHR20982:SF3 RIBOSOME RECYCLING FACTOR MITOCHONDRIAL RIBOSOME RECYCLING FACTOR PSEUDO 1 ribonucleoprotein complex binding#GO:0043021;ribosome binding#GO:0043022;protein-containing complex binding#GO:0044877;binding#GO:0005488 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;translation#GO:0006412;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 translation release factor#PC00225;translation factor#PC00223;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000021080.1|UniProtKB=H2XUQ0 H2XUQ0 PTHR23102:SF24 CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 4-RELATED CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 4 RNA splicing factor#PC00148;RNA metabolism protein#PC00031;RNA processing factor#PC00147 CIOIN|Ensembl=ENSCING00000019659.1|UniProtKB=H2XXX4 H2XXX4 PTHR12577:SF6 DACHSHUND DACHSHUND, ISOFORM B sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 CIOIN|Ensembl=ENSCING00000007227.3|UniProtKB=F6VL03 F6VL03 PTHR11157:SF126 FATTY ACID ACYL TRANSFERASE-RELATED ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824 organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;monocarboxylic acid biosynthetic process#GO:0072330;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;organic acid metabolic process#GO:0006082;membrane lipid biosynthetic process#GO:0046467;sphingolipid metabolic process#GO:0006665;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;fatty acid metabolic process#GO:0006631;membrane lipid metabolic process#GO:0006643;nitrogen compound metabolic process#GO:0006807;small molecule biosynthetic process#GO:0044283;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;sphingolipid biosynthetic process#GO:0030148;fatty acid biosynthetic process#GO:0006633;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 acyltransferase#PC00042 CIOIN|Ensembl=ENSCING00000016009.2|UniProtKB=H2Y296 H2Y296 PTHR31545:SF5 SEEDY PROTEIN A/C FAMILY MEMBER SPEEDY PROTEIN A CIOIN|Ensembl=ENSCING00000020390.1|UniProtKB=Q8I7E3 Q8I7E3 ar20 PTHR22629:SF0 ARP2/3 COMPLEX 20 KD SUBUNIT ACTIN-RELATED PROTEIN 2_3 COMPLEX SUBUNIT 4 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;Arp2/3 complex-mediated actin nucleation#GO:0034314;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;Arp2/3 protein complex#GO:0005885;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Arp2/3#P00876;Cytoskeletal regulation by Rho GTPase#P00016>ARP2/3#P00511 CIOIN|Ensembl=ENSCING00000009234.3|UniProtKB=F6W1F7 F6W1F7 LOC101242287 PTHR48015:SF33 SERINE/THREONINE-PROTEIN KINASE TAO SERINE_THREONINE-PROTEIN KINASE HIPPO transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of MAPK cascade#GO:0043408;signal transduction#GO:0007165;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;regulation of signaling#GO:0023051;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular process#GO:0009987;regulation of intracellular signal transduction#GO:1902531;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000017966.1|UniProtKB=H2XZI6 H2XZI6 PTHR12861:SF3 TRANSLOCON-ASSOCIATED PROTEIN, BETA SUBUNIT PRECURSOR TRAP-BETA SIGNAL SEQUENCE RECEPTOR BETA SUBUNIT TRANSLOCON-ASSOCIATED PROTEIN SUBUNIT BETA membrane traffic protein#PC00150 CIOIN|Ensembl=ENSCING00000016280.2|UniProtKB=F6YPQ4 F6YPQ4 LOC100177072 PTHR18842:SF2 INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASE 1-BINDING PROTEIN 1 INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASE 1-BINDING PROTEIN 1 CIOIN|Ensembl=ENSCING00000012110.2|UniProtKB=F6V951 F6V951 LOC100181397 PTHR12242:SF45 OS02G0130600 PROTEIN-RELATED MARVEL DOMAIN-CONTAINING PROTEIN cellular anatomical entity#GO:0110165;membrane#GO:0016020 CIOIN|Ensembl=ENSCING00000001647.3|UniProtKB=F6TT48 F6TT48 PTHR32455:SF1 SPERM ACROSOME-ASSOCIATED PROTEIN 9 SPERM ACROSOME-ASSOCIATED PROTEIN 9 acrosomal vesicle#GO:0001669;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;ciliary base#GO:0097546;secretory granule#GO:0030141;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;sperm flagellum#GO:0036126;cytoplasm#GO:0005737;motile cilium#GO:0031514;endomembrane system#GO:0012505;9+2 motile cilium#GO:0097729;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cell projection#GO:0042995;cilium#GO:0005929;secretory vesicle#GO:0099503 CIOIN|Ensembl=ENSCING00000012234.2|UniProtKB=F7B5V8 F7B5V8 PTHR21724:SF109 SHKT DOMAIN-CONTAINING PROTEIN SHKT DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000022663.1|UniProtKB=H2XX36 H2XX36 PTHR12733:SF3 MITOCHONDRIAL ATP SYNTHASE B CHAIN ATP SYNTHASE F(0) COMPLEX SUBUNIT B1, MITOCHONDRIAL ATP synthase#PC00002;primary active transporter#PC00068;transporter#PC00227 CIOIN|Ensembl=ENSCING00000019444.1|UniProtKB=H2XPU1 H2XPU1 PTHR11202:SF22 SPROUTY-RELATED, EVH1 DOMAIN-CONTAINING PROTEIN FAMILY MEMBER PROTEIN ENABLED scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000005788.3|UniProtKB=F6RMX1 F6RMX1 PTHR20967:SF0 PROHORMONE-4 PROHORMONE-4 CIOIN|Ensembl=ENSCING00000018915.1|UniProtKB=H2XTS0 H2XTS0 PTHR13282:SF6 PROTEIN FAM32A PROTEIN FAM32A intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000004208.3|UniProtKB=F6YGT6 F6YGT6 PTHR12247:SF131 POLYCOMB GROUP PROTEIN LD05287P protein binding#GO:0005515;protein-containing complex binding#GO:0044877;histone binding#GO:0042393;binding#GO:0005488;chromatin binding#GO:0003682 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of biosynthetic process#GO:0009890;negative regulation of RNA metabolic process#GO:0051253;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of metabolic process#GO:0009892;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 CIOIN|Ensembl=ENSCING00000006533.3|UniProtKB=F6PGY3 F6PGY3 PTHR11473:SF24 AROMATIC AMINO ACID HYDROXYLASE PHENYLALANINE-4-HYDROXYLASE oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000013352.2|UniProtKB=F6YWZ8 F6YWZ8 PTHR23339:SF109 TYROSINE SPECIFIC PROTEIN PHOSPHATASE AND DUAL SPECIFICITY PROTEIN PHOSPHATASE TYR_PHOSPHATASE_2 DOMAIN-CONTAINING PROTEIN hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;protein tyrosine phosphatase activity#GO:0004725;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cell projection organization#GO:0030030;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 protein phosphatase#PC00195;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000023127.1|UniProtKB=H2XLY3 H2XLY3 PTHR13555:SF25 C2H2 ZINC FINGER CGI-62-RELATED ZINC FINGER C2HC DOMAIN-CONTAINING PROTEIN 1A C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 CIOIN|Ensembl=ENSCING00000003979.3|UniProtKB=F6Z241 F6Z241 PTHR45667:SF9 S-ADENOSYLMETHIONINE MITOCHONDRIAL CARRIER PROTEIN MITOCHONDRIAL S-ADENOSYLMETHIONINE CARRIER PROTEIN transmembrane transporter activity#GO:0022857;organic cation transmembrane transporter activity#GO:0015101;transporter activity#GO:0005215 envelope#GO:0031975;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227 mitochondrial carrier protein#PC00158;secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000011348.2|UniProtKB=F6UX64 F6UX64 PTHR24347:SF412 SERINE/THREONINE-PROTEIN KINASE SERINE_THREONINE-PROTEIN KINASE H1 HOMOLOG-RELATED non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CaMK#P00847;Ionotropic glutamate receptor pathway#P00037>CaMKII#P01023 CIOIN|Ensembl=ENSCING00000002916.3|UniProtKB=F7BJM0 F7BJM0 PTHR46485:SF4 LIM DOMAIN KINASE 1 LIM DOMAIN KINASE 1 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actin filament-based process#GO:0030029;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987;organelle organization#GO:0006996 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000013703.2|UniProtKB=F6PRN9 F6PRN9 PTHR14553:SF1 UNCHARACTERIZED PROTEIN C1ORF50 SIMILAR TO CHROMOSOME 1 OPEN READING FRAME 50 CIOIN|Ensembl=ENSCING00000007415.3|UniProtKB=F7B8N2 F7B8N2 PTHR15576:SF1 RIBITOL-5-PHOSPHATE XYLOSYLTRANSFERASE 1 RIBITOL-5-PHOSPHATE XYLOSYLTRANSFERASE 1 UDP-xylosyltransferase activity#GO:0035252;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;xylosyltransferase activity#GO:0042285;pentosyltransferase activity#GO:0016763;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;protein O-linked glycosylation#GO:0006493;protein O-linked mannosylation#GO:0035269;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;protein mannosylation#GO:0035268;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085;mannosylation#GO:0097502 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000002181.3|UniProtKB=F6SS61 F6SS61 PTHR10466:SF0 PHOSPHOMANNOMUTASE PHOSPHOMANNOMUTASE isomerase activity#GO:0016853;intramolecular transferase activity#GO:0016866;catalytic activity#GO:0003824 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;monosaccharide metabolic process#GO:0005996;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein N-linked glycosylation#GO:0006487;hexose metabolic process#GO:0019318;protein metabolic process#GO:0019538;carbohydrate metabolic process#GO:0005975;glycoprotein metabolic process#GO:0009100;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 mutase#PC00160 Mannose metabolism#P02752>P-Mannose mutase#P03019 CIOIN|Ensembl=ENSCING00000009096.3|UniProtKB=F6QDT9 F6QDT9 LOC100177957 PTHR24416:SF349 TYROSINE-PROTEIN KINASE RECEPTOR TYROSINE-PROTEIN KINASE RYK signaling receptor activity#GO:0038023;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;molecular transducer activity#GO:0060089;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672;transmembrane signaling receptor activity#GO:0004888 signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051896;positive regulation of cellular metabolic process#GO:0031325;developmental process#GO:0032502;positive regulation of molecular function#GO:0044093;positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051897;regulation of cellular component organization#GO:0051128;regulation of catalytic activity#GO:0050790;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;regulation of molecular function#GO:0065009;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;positive regulation of phosphorylation#GO:0042327;cellular response to stimulus#GO:0051716;positive regulation of catalytic activity#GO:0043085;multicellular organism development#GO:0007275;positive regulation of phosphorus metabolic process#GO:0010562;regulation of plasma membrane bounded cell projection organization#GO:0120035;cell communication#GO:0007154;cellular process#GO:0009987;regulation of neuron projection development#GO:0010975;positive regulation of cellular process#GO:0048522;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphate metabolic process#GO:0045937;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;regulation of cell projection organization#GO:0031344;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;positive regulation of kinase activity#GO:0033674;multicellular organismal process#GO:0032501;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 receptor complex#GO:0043235;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 CIOIN|Ensembl=ENSCING00000006747.3|UniProtKB=F6XBC5 F6XBC5 PTHR47634:SF9 PROTEIN KINASE DOMAIN-CONTAINING PROTEIN-RELATED PROTEIN KINASE DOMAIN-CONTAINING PROTEIN-RELATED transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;RNA processing#GO:0006396;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;protein-RNA complex assembly#GO:0022618;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of mRNA processing#GO:0050684;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;protein phosphorylation#GO:0006468;cellular component organization#GO:0016043;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;regulation of macromolecule metabolic process#GO:0060255;protein-containing complex organization#GO:0043933;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;ribonucleoprotein complex biogenesis#GO:0022613;biological regulation#GO:0065007;mRNA processing#GO:0006397;peptidyl-serine modification#GO:0018209;protein-RNA complex organization#GO:0071826;RNA splicing, via transesterification reactions#GO:0000375;spliceosomal complex assembly#GO:0000245;regulation of metabolic process#GO:0019222;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323 CIOIN|Ensembl=ENSCING00000017894.1|UniProtKB=A0A1W5BL24 A0A1W5BL24 LOC113474010 PTHR46989:SF3 USP DOMAIN-CONTAINING PROTEIN USPA DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000023482.1|UniProtKB=H2XWZ0 H2XWZ0 LOC100182514 PTHR23273:SF172 REPLICATION FACTOR A 1, RFA1 REPLICATION PROTEIN A 70 KDA DNA-BINDING SUBUNIT sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;single-stranded telomeric DNA binding#GO:0043047;single-stranded DNA binding#GO:0003697;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;damaged DNA binding#GO:0003684;telomeric DNA binding#GO:0042162 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;telomere maintenance via telomere lengthening#GO:0010833;double-strand break repair#GO:0006302;telomere organization#GO:0032200;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;telomere maintenance#GO:0000723;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;recombinational repair#GO:0000725;reproductive process#GO:0022414;telomere maintenance via telomerase#GO:0007004;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleotide-excision repair#GO:0006289;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;meiotic cell cycle#GO:0051321;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular component organization#GO:0016043;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;double-strand break repair via homologous recombination#GO:0000724;cellular process#GO:0009987;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;response to stress#GO:0006950;reproduction#GO:0000003;organelle organization#GO:0006996;chromosome organization#GO:0051276;DNA biosynthetic process#GO:0071897;sexual reproduction#GO:0019953;cell cycle#GO:0007049;aromatic compound biosynthetic process#GO:0019438;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-DNA complex#GO:0032993;replisome#GO:0030894;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nuclear replication fork#GO:0043596;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513;replication fork#GO:0005657 DNA metabolism protein#PC00009 CIOIN|Ensembl=ENSCING00000009427.3|UniProtKB=F6TL65 F6TL65 PTHR24300:SF397 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 2U1 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;tetrapyrrole binding#GO:0046906;steroid hydroxylase activity#GO:0008395;oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497;heme binding#GO:0020037 response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;response to chemical#GO:0042221;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 oxygenase#PC00177;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000009411.3|UniProtKB=F6TM04 F6TM04 PTHR14241:SF32 INTERFERON-INDUCED PROTEIN 44 VWFA DOMAIN-CONTAINING PROTEIN-RELATED CIOIN|Ensembl=ENSCING00000005564.3|UniProtKB=F6URQ9 F6URQ9 PTHR11208:SF45 RNA-BINDING PROTEIN RELATED SPLICING FACTOR 1 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 regulation of nitrogen compound metabolic process#GO:0051171;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of RNA splicing#GO:0043484;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of mRNA processing#GO:0050684;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;regulation of mRNA metabolic process#GO:1903311 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA splicing factor#PC00148;RNA processing factor#PC00147;RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000023347.1|UniProtKB=Q4H3J9 Q4H3J9 Ci-Fos PTHR23351:SF24 FOS TRANSCRIPTION FACTOR-RELATED ACTIVATING TRANSCRIPTION FACTOR 3-RELATED DNA-binding transcription factor#PC00218;basic leucine zipper transcription factor#PC00056 CIOIN|Ensembl=ENSCING00000021521.1|UniProtKB=H2XV81 H2XV81 LOC100186258 PTHR46421:SF1 PROGRAMMED CELL DEATH PROTEIN 2-LIKE PROGRAMMED CELL DEATH PROTEIN 2-LIKE CIOIN|Ensembl=ENSCING00000005175.3|UniProtKB=F6Z194 F6Z194 LOC100182155 PTHR47958:SF104 ATP-DEPENDENT RNA HELICASE DBP3 ATP-DEPENDENT RNA HELICASE WM6 catalytic activity, acting on RNA#GO:0140098;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;helicase activity#GO:0004386;ATP-dependent activity#GO:0140657;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;catalytic activity, acting on a nucleic acid#GO:0140640;mRNA binding#GO:0003729 RNA helicase#PC00032 CIOIN|Ensembl=ENSCING00000022975.1|UniProtKB=H2XNI4 H2XNI4 LOC100182370 PTHR15168:SF0 CYTOCHROME B-245 LIGHT CHAIN CYTOCHROME B-245 LIGHT CHAIN CIOIN|Ensembl=ENSCING00000005969.3|UniProtKB=F6V519 F6V519 PTHR11908:SF132 XANTHINE DEHYDROGENASE ALDEHYDE OXIDASE 1-RELATED oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 oxidoreductase#PC00176 Adenine and hypoxanthine salvage pathway#P02723>Xanthine dehydrogenase#P02809;Purine metabolism#P02769>Xanthine Oxidase#P03116 CIOIN|Ensembl=ENSCING00000019285.1|UniProtKB=F6UQF7 F6UQF7 PTHR23503:SF8 SOLUTE CARRIER FAMILY 2 FACILITATED GLUCOSE TRANSPORTER PROTEIN 1 transmembrane transporter activity#GO:0022857;sugar transmembrane transporter activity#GO:0051119;transporter activity#GO:0005215;carbohydrate transmembrane transporter activity#GO:0015144 localization#GO:0051179;organic substance transport#GO:0071702;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810;cellular process#GO:0009987;carbohydrate transmembrane transport#GO:0034219;carbohydrate transport#GO:0008643 cellular anatomical entity#GO:0110165;membrane#GO:0016020 secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000024257.1|UniProtKB=H2XZE7 H2XZE7 PTHR45694:SF18 GLUTAREDOXIN 2 GLUTAREDOXIN-1-RELATED disulfide oxidoreductase activity#GO:0015036;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;response to stress#GO:0006950;cellular response to chemical stimulus#GO:0070887;response to chemical#GO:0042221;cellular response to oxidative stress#GO:0034599;response to oxidative stress#GO:0006979;cellular response to stress#GO:0033554;cellular process#GO:0009987 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000004583.3|UniProtKB=F6WQE3 F6WQE3 PTHR12978:SF0 HISTIDINE TRIAD HIT PROTEIN MEMBER M7GPPPX DIPHOSPHATASE RNA binding#GO:0003723;nucleic acid binding#GO:0003676;RNA cap binding#GO:0000339;binding#GO:0005488;organic cyclic compound binding#GO:0097159 negative regulation of gene expression#GO:0010629;regulation of catabolic process#GO:0009894;heterocycle catabolic process#GO:0046700;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;nucleobase-containing compound metabolic process#GO:0006139;RNA destabilization#GO:0050779;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;regulation of RNA stability#GO:0043487;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;positive regulation of mRNA catabolic process#GO:0061014;regulation of cellular process#GO:0050794;post-transcriptional regulation of gene expression#GO:0010608;positive regulation of catabolic process#GO:0009896;mRNA destabilization#GO:0061157;nucleobase-containing compound catabolic process#GO:0034655;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;regulation of mRNA stability#GO:0043488;RNA metabolic process#GO:0016070;positive regulation of cellular catabolic process#GO:0031331;cellular nitrogen compound catabolic process#GO:0044270;RNA decapping#GO:0110154;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;mRNA catabolic process#GO:0006402;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;regulation of gene expression#GO:0010468;organic substance catabolic process#GO:1901575;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;positive regulation of mRNA metabolic process#GO:1903313;heterocycle metabolic process#GO:0046483;negative regulation of biosynthetic process#GO:0009890;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;positive regulation of RNA metabolic process#GO:0051254 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;nucleus#GO:0005634;P-body#GO:0000932;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000002625.3|UniProtKB=F6QR87 F6QR87 PTHR24416:SF539 TYROSINE-PROTEIN KINASE RECEPTOR RECEPTOR PROTEIN-TYROSINE KINASE signaling receptor activity#GO:0038023;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;molecular transducer activity#GO:0060089;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672;transmembrane signaling receptor activity#GO:0004888 signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;positive regulation of cellular metabolic process#GO:0031325;developmental process#GO:0032502;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;regulation of molecular function#GO:0065009;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;positive regulation of phosphorylation#GO:0042327;cellular response to stimulus#GO:0051716;positive regulation of catalytic activity#GO:0043085;multicellular organism development#GO:0007275;positive regulation of phosphorus metabolic process#GO:0010562;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphate metabolic process#GO:0045937;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;multicellular organismal process#GO:0032501;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 receptor complex#GO:0043235;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 CIOIN|Ensembl=ENSCING00000001021.3|UniProtKB=F6W0H5 F6W0H5 PTHR24393:SF15 ZINC FINGER PROTEIN IP01243P-RELATED DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 CIOIN|Ensembl=ENSCING00000023980.1|UniProtKB=F6UAK1 F6UAK1 PTHR19143:SF458 FIBRINOGEN/TENASCIN/ANGIOPOEITIN FIBRINOGEN C-TERMINAL DOMAIN-CONTAINING PROTEIN-RELATED external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 CIOIN|Ensembl=ENSCING00000003045.3|UniProtKB=F6Q6E0 F6Q6E0 LOC100180066 PTHR31102:SF1 FAMILY NOT NAMED CATION_H+ EXCHANGER DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000001344.2|UniProtKB=F6SXJ8 F6SXJ8 PTHR17008:SF1 MEIOSIS-EXPRESSED GENE 1 PROTEIN MEIOSIS EXPRESSED GENE 1 PROTEIN HOMOLOG membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000006254.3|UniProtKB=A0A1W3JVH5 A0A1W3JVH5 LOC100186389 PTHR13448:SF0 TRANSMEMBRANE PROTEIN 214 TRANSMEMBRANE PROTEIN 214 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000003166.3|UniProtKB=F6QIH1 F6QIH1 PTHR16172:SF2 MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 6-LIKE MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 6 cellular anatomical entity#GO:0110165;membrane#GO:0016020 CIOIN|Ensembl=ENSCING00000021946.1|UniProtKB=H2XXH6 H2XXH6 LOC100181151 PTHR24070:SF268 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY RAS-RELATED PROTEIN M-RAS GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;ion binding#GO:0043167;anion binding#GO:0043168 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 small GTPase#PC00208;G-protein#PC00020 EGF receptor signaling pathway#P00018>Ras#P00552 CIOIN|Ensembl=ENSCING00000014091.2|UniProtKB=F7BBI8 F7BBI8 PTHR46169:SF29 DNA REPLICATION-RELATED ELEMENT FACTOR, ISOFORM A DNA REPLICATION-RELATED ELEMENT FACTOR, ISOFORM A regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA metabolism protein#PC00009 CIOIN|Ensembl=ENSCING00000007539.3|UniProtKB=F6TVI5 F6TVI5 LOC101242403 PTHR12471:SF7 VACUOLAR ATP SYNTHASE SUBUNIT S1 V-TYPE PROTON ATPASE SUBUNIT S1 molecular function activator activity#GO:0140677;ATPase activator activity#GO:0001671;molecular function regulator activity#GO:0098772 regulation of pH#GO:0006885;intracellular monoatomic cation homeostasis#GO:0030003;biological regulation#GO:0065007;monoatomic cation homeostasis#GO:0055080;homeostatic process#GO:0042592;intracellular monoatomic ion homeostasis#GO:0006873;chemical homeostasis#GO:0048878;cellular homeostasis#GO:0019725;regulation of cellular pH#GO:0030641;intracellular chemical homeostasis#GO:0055082;monoatomic ion homeostasis#GO:0050801 ATPase complex#GO:1904949;membrane protein complex#GO:0098796;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;membrane#GO:0016020;proton-transporting two-sector ATPase complex#GO:0016469;catalytic complex#GO:1902494 ATP synthase#PC00002;primary active transporter#PC00068;transporter#PC00227 CIOIN|Ensembl=ENSCING00000014715.2|UniProtKB=F6ZBR4 F6ZBR4 LOC100180163 PTHR12892:SF11 FGF RECEPTOR ACTIVATING PROTEIN 1 POST-GPI ATTACHMENT TO PROTEINS FACTOR 2 lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;phospholipid biosynthetic process#GO:0008654;macromolecule modification#GO:0043412;organophosphate biosynthetic process#GO:0090407;phosphatidylinositol biosynthetic process#GO:0006661;glycolipid metabolic process#GO:0006664;protein modification process#GO:0036211;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;lipid biosynthetic process#GO:0008610;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;protein lipidation#GO:0006497;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;glycerolipid biosynthetic process#GO:0045017;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;glycerophospholipid metabolic process#GO:0006650;phosphatidylinositol metabolic process#GO:0046488;organic substance biosynthetic process#GO:1901576;liposaccharide metabolic process#GO:1903509;cellular process#GO:0009987;GPI anchor metabolic process#GO:0006505;membrane lipid biosynthetic process#GO:0046467;lipoprotein biosynthetic process#GO:0042158;primary metabolic process#GO:0044238;GPI anchor biosynthetic process#GO:0006506;carbohydrate derivative biosynthetic process#GO:1901137;membrane lipid metabolic process#GO:0006643;glycerophospholipid biosynthetic process#GO:0046474;glycolipid biosynthetic process#GO:0009247;organophosphate metabolic process#GO:0019637;lipoprotein metabolic process#GO:0042157;cellular lipid metabolic process#GO:0044255 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000017357.2|UniProtKB=F6X1I9 F6X1I9 PTHR31120:SF6 METALLOPROTEASE TIKI METALLOPROTEASE TIKI HOMOLOG hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular anatomical entity#GO:0110165;membrane#GO:0016020 metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000005349.3|UniProtKB=F7ALR4 F7ALR4 PTHR43734:SF4 PHYTOENE DESATURASE AMINE OXIDASE DOMAIN-CONTAINING PROTEIN dehydrogenase#PC00092;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000010696.3|UniProtKB=F6VVR6 F6VVR6 LOC100183745 PTHR11089:SF9 GTP-BINDING PROTEIN-RELATED NUCLEOLAR GTP-BINDING PROTEIN 2 intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000003788.3|UniProtKB=F7AW28 F7AW28 PTHR21052:SF0 SPERMATOGENESIS ASSOCIATED 11-RELATED ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE ALKB HOMOLOG 7, MITOCHONDRIAL CIOIN|Ensembl=ENSCING00000013600.2|UniProtKB=F6V1Z8 F6V1Z8 PTHR11848:SF302 TGF-BETA FAMILY TGF-BETA FAMILY PROFILE DOMAIN-CONTAINING PROTEIN molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;cytokine activity#GO:0005125;protein binding#GO:0005515;signaling receptor binding#GO:0005102 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 CIOIN|Ensembl=ENSCING00000018406.1|UniProtKB=H2XUX1 H2XUX1 PTHR47084:SF1 SERINE PALMITOYLTRANSFERASE SMALL SUBUNIT A SERINE PALMITOYLTRANSFERASE SMALL SUBUNIT A palmitoyltransferase activity#GO:0016409;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;membrane lipid biosynthetic process#GO:0046467;sphingolipid metabolic process#GO:0006665;primary metabolic process#GO:0044238;ceramide metabolic process#GO:0006672;amide biosynthetic process#GO:0043604;membrane lipid metabolic process#GO:0006643;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;ceramide biosynthetic process#GO:0046513;cellular lipid metabolic process#GO:0044255;amide metabolic process#GO:0043603;sphingolipid biosynthetic process#GO:0030148;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;endoplasmic reticulum protein-containing complex#GO:0140534;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;catalytic complex#GO:1902494;transferase complex#GO:1990234;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000024941.1|UniProtKB=H2XNH6 H2XNH6 LOC100185340 PTHR14503:SF4 MITOCHONDRIAL RIBOSOMAL PROTEIN 34 FAMILY MEMBER LARGE RIBOSOMAL SUBUNIT PROTEIN BL34M ribosomal protein#PC00202;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000017308.2|UniProtKB=F6ZZX7 F6ZZX7 LOC100179637 PTHR45862:SF1 PROTEIN SGT1 HOMOLOG PROTEIN SGT1 HOMOLOG CIOIN|Ensembl=ENSCING00000012581.1|UniProtKB=F6Y4B4 F6Y4B4 PTHR22802:SF456 C-TYPE LECTIN SUPERFAMILY MEMBER FI01427P membrane traffic protein#PC00150 CIOIN|Ensembl=ENSCING00000021131.1|UniProtKB=H2XLD1 H2XLD1 PTHR15830:SF10 TELOMERE LENGTH REGULATION PROTEIN TEL2 FAMILY MEMBER TELOMERE LENGTH REGULATION PROTEIN TEL2 HOMOLOG sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;telomeric DNA binding#GO:0042162;heat shock protein binding#GO:0031072;protein binding#GO:0005515;Hsp90 protein binding#GO:0051879 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein folding#GO:0006457;'de novo' protein folding#GO:0006458;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000001557.3|UniProtKB=F6YJN9 F6YJN9 LOC100185861 PTHR15901:SF15 TESTICULAR HAPLOID EXPRESSED GENE PROTEIN TESTICULAR HAPLOID EXPRESSED GENE PROTEIN-LIKE CIOIN|Ensembl=ENSCING00000006493.3|UniProtKB=F6RMP9 F6RMP9 PTHR24416:SF634 TYROSINE-PROTEIN KINASE RECEPTOR DISCOIDIN DOMAIN-CONTAINING RECEPTOR TYROSINE KINASE B signaling receptor activity#GO:0038023;protein tyrosine kinase activity#GO:0004713;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;protein kinase activity#GO:0004672;transmembrane signaling receptor activity#GO:0004888;transferase activity#GO:0016740;transmembrane receptor protein kinase activity#GO:0019199;collagen binding#GO:0005518;molecular transducer activity#GO:0060089;protein-containing complex binding#GO:0044877;catalytic activity, acting on a protein#GO:0140096 signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051896;positive regulation of cellular metabolic process#GO:0031325;developmental process#GO:0032502;positive regulation of molecular function#GO:0044093;positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051897;regulation of cellular component organization#GO:0051128;regulation of catalytic activity#GO:0050790;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;regulation of molecular function#GO:0065009;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;positive regulation of phosphorylation#GO:0042327;cellular response to stimulus#GO:0051716;positive regulation of catalytic activity#GO:0043085;multicellular organism development#GO:0007275;positive regulation of phosphorus metabolic process#GO:0010562;cell communication#GO:0007154;regulation of plasma membrane bounded cell projection organization#GO:0120035;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;regulation of neuron projection development#GO:0010975;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphate metabolic process#GO:0045937;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;anatomical structure development#GO:0048856;regulation of cell projection organization#GO:0031344;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;positive regulation of kinase activity#GO:0033674;multicellular organismal process#GO:0032501;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 receptor complex#GO:0043235;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 CIOIN|Ensembl=ENSCING00000021088.1|UniProtKB=H2XMX2 H2XMX2 PTHR12959:SF11 GPI TRANSAMIDASE COMPONENT PIG-T-RELATED GPI TRANSAMIDASE COMPONENT PIG-T lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;phospholipid biosynthetic process#GO:0008654;macromolecule modification#GO:0043412;phosphatidylinositol biosynthetic process#GO:0006661;organophosphate biosynthetic process#GO:0090407;glycolipid metabolic process#GO:0006664;protein modification process#GO:0036211;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;lipid biosynthetic process#GO:0008610;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;protein lipidation#GO:0006497;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;glycerolipid biosynthetic process#GO:0045017;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;glycerophospholipid metabolic process#GO:0006650;phosphatidylinositol metabolic process#GO:0046488;organic substance biosynthetic process#GO:1901576;liposaccharide metabolic process#GO:1903509;cellular process#GO:0009987;membrane lipid biosynthetic process#GO:0046467;GPI anchor metabolic process#GO:0006505;lipoprotein biosynthetic process#GO:0042158;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;GPI anchor biosynthetic process#GO:0006506;membrane lipid metabolic process#GO:0006643;glycerophospholipid biosynthetic process#GO:0046474;glycolipid biosynthetic process#GO:0009247;organophosphate metabolic process#GO:0019637;lipoprotein metabolic process#GO:0042157;cellular lipid metabolic process#GO:0044255 membrane protein complex#GO:0098796;peptidase complex#GO:1905368;endoplasmic reticulum protein-containing complex#GO:0140534;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;endopeptidase complex#GO:1905369;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 CIOIN|Ensembl=ENSCING00000013838.2|UniProtKB=F6QKU2 F6QKU2 LOC100181297 PTHR47163:SF2 DDE_TNP_IS1595 DOMAIN-CONTAINING PROTEIN SI:DKEY-17M8.2 CIOIN|Ensembl=ENSCING00000008549.2|UniProtKB=F6XQJ5 F6XQJ5 PTHR24418:SF447 TYROSINE-PROTEIN KINASE TYROSINE PROTEIN-KINASE SRC-1 protein tyrosine kinase activity#GO:0004713;non-membrane spanning protein tyrosine kinase activity#GO:0004715;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein binding#GO:0005515;catalytic activity, acting on a protein#GO:0140096;signaling receptor binding#GO:0005102;kinase activity#GO:0016301;protein kinase activity#GO:0004672 response to external biotic stimulus#GO:0043207;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;immune response#GO:0006955;developmental process#GO:0032502;cell communication#GO:0007154;cellular process#GO:0009987;defense response to symbiont#GO:0140546;regulation of biological process#GO:0050789;immune system process#GO:0002376;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;cell differentiation#GO:0030154;enzyme-linked receptor protein signaling pathway#GO:0007167;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological process involved in interspecies interaction between organisms#GO:0044419;biological regulation#GO:0065007;innate immune response#GO:0045087;defense response#GO:0006952;signaling#GO:0023052;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169 non-receptor tyrosine protein kinase#PC00168 Parkinson disease#P00049>Src kinase#P01230;Integrin signalling pathway#P00034>Src#P00940 CIOIN|Ensembl=ENSCING00000013626.2|UniProtKB=F6V0S1 F6V0S1 LOC100175793 PTHR43591:SF101 METHYLTRANSFERASE METHYLTRANSFERASE-LIKE PROTEIN 27 methyltransferase#PC00155;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000014527.2|UniProtKB=F6VN74 F6VN74 PTHR11043:SF0 ZETA-COAT PROTEIN COATOMER SUBUNIT ZETA cellular localization#GO:0051641;intra-Golgi vesicle-mediated transport#GO:0006891;macromolecule localization#GO:0033036;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;coated vesicle#GO:0030135;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;vesicle coat#GO:0030120;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;Golgi-associated vesicle membrane#GO:0030660;protein-containing complex#GO:0032991;COPI vesicle coat#GO:0030126;endomembrane system#GO:0012505;membrane coat#GO:0030117;coated vesicle membrane#GO:0030662;COPI-coated vesicle#GO:0030137;Golgi-associated vesicle#GO:0005798;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;coated membrane#GO:0048475;cytoplasmic vesicle membrane#GO:0030659 vesicle coat protein#PC00235 CIOIN|Ensembl=ENSCING00000002444.3|UniProtKB=F6QNQ9 F6QNQ9 PTHR23281:SF18 MERLIN/MOESIN/EZRIN/RADIXIN MOESIN_EZRIN_RADIXIN HOMOLOG 1 cell adhesion molecule binding#GO:0050839;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;actin binding#GO:0003779;binding#GO:0005488 regulation of anatomical structure morphogenesis#GO:0022603;regulation of organelle organization#GO:0033043;positive regulation of transport#GO:0051050;regulation of localization#GO:0032879;regulation of cellular component organization#GO:0051128;regulation of cellular localization#GO:0060341;regulation of vesicle-mediated transport#GO:0060627;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of cell shape#GO:0008360;regulation of transport#GO:0051049;regulation of biological quality#GO:0065008;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of cellular component biogenesis#GO:0044087;regulation of organelle assembly#GO:1902115;biological regulation#GO:0065007;positive regulation of protein localization#GO:1903829;positive regulation of biological process#GO:0048518;regulation of protein localization#GO:0032880 actin-based cell projection#GO:0098858;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;filopodium#GO:0030175 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 CIOIN|Ensembl=ENSCING00000019559.1|UniProtKB=H2XXZ6 H2XXZ6 PTHR15176:SF1 NEPHROCYSTIN NEPHROCYSTIN-1 localization#GO:0051179;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;anatomical structure morphogenesis#GO:0009653;epithelium development#GO:0060429;anatomical structure development#GO:0048856;developmental process#GO:0032502;tissue morphogenesis#GO:0048729;morphogenesis of an epithelium#GO:0002009;cellular process#GO:0009987;tissue development#GO:0009888;protein localization#GO:0008104 cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;cilium#GO:0005929;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular anatomical structure#GO:0005622 cell junction protein#PC00070 CIOIN|Ensembl=ENSCING00000007421.3|UniProtKB=F7B898 F7B898 PTHR47960:SF17 DEAD-BOX ATP-DEPENDENT RNA HELICASE 50 ATP-DEPENDENT RNA HELICASE DDX6-RELATED nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 negative regulation of gene expression#GO:0010629;negative regulation of cellular metabolic process#GO:0031324;cellular component biogenesis#GO:0044085;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;regulation of amide metabolic process#GO:0034248;regulation of nitrogen compound metabolic process#GO:0051171;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;non-membrane-bounded organelle assembly#GO:0140694;P-body assembly#GO:0033962;negative regulation of cellular process#GO:0048523;cellular component assembly#GO:0022607;negative regulation of biosynthetic process#GO:0009890;cellular component organization#GO:0016043;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;cellular process#GO:0009987;negative regulation of nitrogen compound metabolic process#GO:0051172;organelle assembly#GO:0070925;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of translation#GO:0017148;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of translation#GO:0006417;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;P-body#GO:0000932;cytoplasmic stress granule#GO:0010494;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031;RNA helicase#PC00032 CIOIN|Ensembl=ENSCING00000005082.3|UniProtKB=F6ZLB7 F6ZLB7 LOC100176960 PTHR24075:SF5 SEC63 DOMAIN-CONTAINING U5 SMALL NUCLEAR RIBONUCLEOPROTEIN 200 KDA HELICASE catalytic activity, acting on RNA#GO:0140098;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;helicase activity#GO:0004386;ATP-dependent activity#GO:0140657;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;catalytic activity, acting on a nucleic acid#GO:0140640 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;RNA processing#GO:0006396;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;protein-RNA complex assembly#GO:0022618;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;protein-containing complex organization#GO:0043933;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;ribonucleoprotein complex biogenesis#GO:0022613;mRNA processing#GO:0006397;protein-RNA complex organization#GO:0071826;RNA splicing, via transesterification reactions#GO:0000375 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000010582.3|UniProtKB=F6Z4Q2 F6Z4Q2 LOC100181393 PTHR19277:SF161 PENTRAXIN LAMININ G DOMAIN-CONTAINING PROTEIN scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000007808.3|UniProtKB=F6YKS6 F6YKS6 PTHR10887:SF341 DNA2/NAM7 HELICASE FAMILY NFX1-TYPE ZINC FINGER-CONTAINING PROTEIN 1 negative regulation of gene expression#GO:0010629;regulatory ncRNA-mediated gene silencing#GO:0031047;negative regulation of cellular metabolic process#GO:0031324;protein-DNA complex organization#GO:0071824;negative regulation of biological process#GO:0048519;negative regulation of biosynthetic process#GO:0009890;heterochromatin formation#GO:0031507;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;negative regulation of gene expression, epigenetic#GO:0045814;cellular process#GO:0009987;epigenetic regulation of gene expression#GO:0040029;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;negative regulation of macromolecule biosynthetic process#GO:0010558;heterochromatin organization#GO:0070828;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;protein-containing complex organization#GO:0043933;regulation of cellular process#GO:0050794;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;chromatin remodeling#GO:0006338;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 RNA polymerase complex#GO:0030880;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622 RNA helicase#PC00032 CIOIN|Ensembl=ENSCING00000018576.1|UniProtKB=H2XSL4 H2XSL4 LOC100178832 PTHR10996:SF114 2-HYDROXYACID DEHYDROGENASE-RELATED GLYOXYLATE_HYDROXYPYRUVATE REDUCTASE A oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000018639.1|UniProtKB=H2XWT2 H2XWT2 LOC100176962 PTHR24068:SF159 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 T ubiquitin-like protein conjugating enzyme activity#GO:0061650;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin conjugating enzyme activity#GO:0061631;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein ubiquitination#GO:0016567;cellular response to stimulus#GO:0051716;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular process#GO:0009987;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;DNA damage response#GO:0006974;response to stress#GO:0006950;nitrogen compound metabolic process#GO:0006807;protein polyubiquitination#GO:0000209;protein metabolic process#GO:0019538;cellular response to stress#GO:0033554;protein modification by small protein conjugation#GO:0032446;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 Ubiquitin proteasome pathway#P00060>E2#P01491 CIOIN|Ensembl=ENSCING00000002034.3|UniProtKB=F6U568 F6U568 PTHR15960:SF5 LD44032P LD44032P protein binding#GO:0005515;ubiquitin-like protein binding#GO:0032182;binding#GO:0005488;ubiquitin binding#GO:0043130 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043162;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endosome membrane#GO:0010008;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;ESCRT I complex#GO:0000813;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle membrane#GO:0030659 CIOIN|Ensembl=ENSCING00000019541.1|UniProtKB=H2XSI9 H2XSI9 PTHR23023:SF226 DIMETHYLANILINE MONOOXYGENASE FLAVIN-CONTAINING MONOOXYGENASE oxygenase#PC00177;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000003666.2|UniProtKB=Q0GTF8 Q0GTF8 INS-L1 PTHR46845:SF1 INSULIN-LIKE GROWTH FACTOR I INSULIN-LIKE GROWTH FACTOR I molecular function activator activity#GO:0140677;binding#GO:0005488;molecular function regulator activity#GO:0098772;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;hormone activity#GO:0005179;signaling receptor binding#GO:0005102 signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051896;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;positive regulation of cell population proliferation#GO:0008284;positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051897;cell population proliferation#GO:0008283;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;positive regulation of response to stimulus#GO:0048584;negative regulation of programmed cell death#GO:0043069;regulation of signal transduction#GO:0009966;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of programmed cell death#GO:0043067;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of apoptotic process#GO:0042981;regulation of cell population proliferation#GO:0042127;cell communication#GO:0007154;insulin-like growth factor receptor signaling pathway#GO:0048009;cellular process#GO:0009987;negative regulation of apoptotic process#GO:0043066;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of protein phosphorylation#GO:0001932;cell surface receptor signaling pathway#GO:0007166;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 growth factor#PC00112 Insulin/IGF pathway-protein kinase B signaling cascade#P00033>Insulin IGF#P00896;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>Insulin IGF#P00882;Gonadotropin-releasing hormone receptor pathway#P06664>IGF-1#P06854 CIOIN|Ensembl=ENSCING00000007389.3|UniProtKB=F6RZC1 F6RZC1 LOC100180385 PTHR24221:SF636 ATP-BINDING CASSETTE SUB-FAMILY B BILE SALT EXPORT PUMP transmembrane transporter activity#GO:0022857;primary active transmembrane transporter activity#GO:0015399;ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 localization#GO:0051179;cellular process#GO:0009987;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810 plasma membrane region#GO:0098590;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;apical part of cell#GO:0045177;plasma membrane#GO:0005886;apical plasma membrane#GO:0016324 ATP-binding cassette (ABC) transporter#PC00003;transporter#PC00227 CIOIN|Ensembl=ENSCING00000006297.3|UniProtKB=F6UBQ5 F6UBQ5 PTHR12333:SF0 COMM DOMAIN CONTAINING PROTEIN 10 COMM DOMAIN-CONTAINING PROTEIN 10 CIOIN|Ensembl=ENSCING00000021999.1|UniProtKB=H2XLG7 H2XLG7 LOC100186131 PTHR15874:SF1 NUCLEOLAR AND SPINDLE-ASSOCIATED PROTEIN 1 NUCLEOLAR AND SPINDLE-ASSOCIATED PROTEIN 1 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 cell division#GO:0051301;cellular localization#GO:0051641;organelle localization#GO:0051640;nuclear division#GO:0000280;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;chromosome condensation#GO:0030261;microtubule cytoskeleton organization involved in mitosis#GO:1902850;mitotic cell cycle process#GO:1903047;chromosome segregation#GO:0007059;mitotic cytokinesis#GO:0000281;mitotic cell cycle#GO:0000278;establishment of localization#GO:0051234;cytoskeleton-dependent cytokinesis#GO:0061640;mitotic nuclear division#GO:0140014;cytoskeleton organization#GO:0007010;mitotic sister chromatid segregation#GO:0000070;establishment of organelle localization#GO:0051656;cytokinesis#GO:0000910;spindle localization#GO:0051653;nuclear chromosome segregation#GO:0098813;sister chromatid segregation#GO:0000819;cellular component organization#GO:0016043;cellular process#GO:0009987;establishment of spindle localization#GO:0051293;mitotic chromosome condensation#GO:0007076;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of mitotic spindle localization#GO:0040001;microtubule-based process#GO:0007017;chromosome organization#GO:0051276;organelle organization#GO:0006996;cell cycle#GO:0007049;establishment of localization in cell#GO:0051649;organelle fission#GO:0048285 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;mitotic spindle#GO:0072686;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cytoskeleton#GO:0005856;spindle#GO:0005819 CIOIN|Ensembl=ENSCING00000025015.1|UniProtKB=F6X1X5 F6X1X5 PTHR22802:SF396 C-TYPE LECTIN SUPERFAMILY MEMBER C-TYPE LECTIN DOMAIN-CONTAINING PROTEIN membrane traffic protein#PC00150 CIOIN|Ensembl=ENSCING00000000830.3|UniProtKB=F6R1Q7 F6R1Q7 LOC100185783 PTHR12378:SF80 DESUMOYLATING ISOPEPTIDASE IP06716P-RELATED hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;protein modification by small protein removal#GO:0070646;protein deubiquitination#GO:0016579;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cysteine protease#PC00081;protease#PC00190 CIOIN|Ensembl=ENSCING00000005097.3|UniProtKB=F7B1D9 F7B1D9 PTHR35169:SF3 FE2OG DIOXYGENASE DOMAIN-CONTAINING PROTEIN PROLYL 4-HYDROXYLASE ALPHA SUBUNIT FE(2+) 2OG DIOXYGENASE DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000000202.3|UniProtKB=A0A1W5BPQ3 A0A1W5BPQ3 LOC113474008 PTHR12403:SF1 TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 2 TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 2-RELATED localization#GO:0051179;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;establishment of localization#GO:0051234;transport#GO:0006810;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;vesicle tethering complex#GO:0099023;TRAPP complex#GO:0030008;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150 CIOIN|Ensembl=ENSCING00000005504.3|UniProtKB=F7AU91 F7AU91 PTHR10676:SF36 DYNEIN HEAVY CHAIN FAMILY PROTEIN DYNEIN HEAVY CHAIN AT 93AB, ISOFORM C cytoskeletal motor activity#GO:0003774;microtubule motor activity#GO:0003777;protein binding#GO:0005515;ATP-dependent activity#GO:0140657;binding#GO:0005488 cilium-dependent cell motility#GO:0060285;microtubule-based process#GO:0007017;cilium or flagellum-dependent cell motility#GO:0001539;microtubule-based movement#GO:0007018;cell motility#GO:0048870;cellular process#GO:0009987;cilium movement involved in cell motility#GO:0060294;cilium movement#GO:0003341 axoneme#GO:0005930;catalytic complex#GO:1902494;cytoplasmic region#GO:0099568;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;microtubule associated complex#GO:0005875;non-membrane-bounded organelle#GO:0043228;motile cilium#GO:0031514;protein-containing complex#GO:0032991;9+2 motile cilium#GO:0097729;microtubule cytoskeleton#GO:0015630;ciliary plasm#GO:0097014;plasma membrane bounded cell projection cytoplasm#GO:0032838;membrane-bounded organelle#GO:0043227;dynein complex#GO:0030286;cell projection#GO:0042995;cytoskeleton#GO:0005856;cilium#GO:0005929 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 Huntington disease#P00029>Dynein complex#P00774 CIOIN|Ensembl=ENSCING00000006628.3|UniProtKB=F6QP05 F6QP05 PTHR11866:SF16 G-PROTEIN COUPLED RECEPTOR FAMILY 1 MEMBER PROSTAGLANDIN E2 RECEPTOR EP4 SUBTYPE-LIKE PROTEIN adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;positive regulation of cytosolic calcium ion concentration#GO:0007204;cell communication#GO:0007154;cellular process#GO:0009987;inflammatory response#GO:0006954;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to stress#GO:0006950;regulation of biological quality#GO:0065008;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;defense response#GO:0006952;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 CIOIN|Ensembl=ENSCING00000011640.2|UniProtKB=F7A686 F7A686 LOC100176080 PTHR11567:SF211 ACID PHOSPHATASE-RELATED PROSTATIC ACID PHOSPHATASE hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 cellular metabolic process#GO:0044237;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;dephosphorylation#GO:0016311;metabolic process#GO:0008152 metabolite interconversion enzyme#PC00262;phosphatase#PC00181 CIOIN|Ensembl=ENSCING00000013376.2|UniProtKB=F6SU61 F6SU61 PTHR43149:SF1 ENOYL-COA HYDRATASE DELTA(3,5)-DELTA(2,4)-DIENOYL-COA ISOMERASE, MITOCHONDRIAL lyase#PC00144;hydratase#PC00120 CIOIN|Ensembl=ENSCING00000002729.3|UniProtKB=F6TQ12 F6TQ12 LOC100178939 PTHR17039:SF0 U3 SMALL NUCLEOLAR RIBONUCLEOPROTEIN PROTEIN MPP10 U3 SMALL NUCLEOLAR RIBONUCLEOPROTEIN PROTEIN MPP10 membrane-enclosed lumen#GO:0031974;small-subunit processome#GO:0032040;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513;90S preribosome#GO:0030686 RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000021794.1|UniProtKB=H2XQN1 H2XQN1 PTHR31493:SF1 NAZO FAMILY MEMBER PROTEIN C19ORF12 CIOIN|Ensembl=ENSCING00000007830.3|UniProtKB=F6WTT2 F6WTT2 PTHR12369:SF11 CHONDROITIN SYNTHASE HEXOSYLTRANSFERASE transferase activity#GO:0016740;catalytic activity#GO:0003824;glycosyltransferase activity#GO:0016757;hexosyltransferase activity#GO:0016758;UDP-glycosyltransferase activity#GO:0008194 glycosyltransferase#PC00111 CIOIN|Ensembl=ENSCING00000021903.1|UniProtKB=H2XM63 H2XM63 PTHR14196:SF0 ODD-SKIPPED - RELATED PROTEIN BOWEL sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;multicellular organism development#GO:0007275;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;embryo development#GO:0009790;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 zinc finger transcription factor#PC00244 CIOIN|Ensembl=ENSCING00000023438.1|UniProtKB=H2XZ14 H2XZ14 LOC100180914 PTHR35247:SF1 TESTIS-EXPRESSED PROTEIN 43 TESTIS-EXPRESSED PROTEIN 43 CIOIN|Ensembl=ENSCING00000004971.3|UniProtKB=F7AI19 F7AI19 PTHR45752:SF196 LEUCINE-RICH REPEAT-CONTAINING GH17740P scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000008109.3|UniProtKB=Q60GS9 Q60GS9 TK PTHR11250:SF0 TACHYKININ TACHYKININ PRECURSOR 1 CIOIN|Ensembl=ENSCING00000015350.2|UniProtKB=F7ANT6 F7ANT6 LOC100181337 PTHR14200:SF11 CYTOCHROME C OXIDASE POLYPEPTIDE CYTOCHROME C OXIDASE SUBUNIT 5A, MITOCHONDRIAL mitochondrial ATP synthesis coupled electron transport#GO:0042775;aerobic respiration#GO:0009060;cellular respiration#GO:0045333;respiratory electron transport chain#GO:0022904;aerobic electron transport chain#GO:0019646;oxidative phosphorylation#GO:0006119;generation of precursor metabolites and energy#GO:0006091;electron transport chain#GO:0022900;ATP synthesis coupled electron transport#GO:0042773;cellular metabolic process#GO:0044237;cellular process#GO:0009987;mitochondrial electron transport, cytochrome c to oxygen#GO:0006123;energy derivation by oxidation of organic compounds#GO:0015980;metabolic process#GO:0008152 envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;cytochrome complex#GO:0070069;respiratory chain complex#GO:0098803;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;respirasome#GO:0070469;protein-containing complex#GO:0032991;mitochondrial envelope#GO:0005740;mitochondrial respirasome#GO:0005746;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227;respiratory chain complex IV#GO:0045277;mitochondrial protein-containing complex#GO:0098798 oxidase#PC00175;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000015777.2|UniProtKB=F6SJR0 F6SJR0 PTHR46212:SF10 PEFLIN PEFLIN vesicle targeting, to, from or within Golgi#GO:0048199;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;vesicle localization#GO:0051648;membrane organization#GO:0061024;transport#GO:0006810;protein-containing complex assembly#GO:0065003;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;vesicle targeting#GO:0006903;Golgi vesicle transport#GO:0048193;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;vesicle budding from membrane#GO:0006900;establishment of localization#GO:0051234;organelle organization#GO:0006996;establishment of vesicle localization#GO:0051650;protein-containing complex organization#GO:0043933;COPII-coated vesicle budding#GO:0090114;vesicle organization#GO:0016050;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;establishment of organelle localization#GO:0051656 CIOIN|Ensembl=ENSCING00000000153.3|UniProtKB=F6Z5W5 F6Z5W5 PTHR12117:SF0 HISTONE ACETYLTRANSFERASE COMPLEX PROLYL 3-HYDROXYLASE OGFOD1 histone modifying enzyme#PC00261 CIOIN|Ensembl=ENSCING00000001275.3|UniProtKB=F6ZVT2 F6ZVT2 LOC100179012 PTHR11741:SF0 ELONGATION FACTOR TS ELONGATION FACTOR TS, MITOCHONDRIAL nucleic acid binding#GO:0003676;translation regulator activity#GO:0045182;translation regulator activity, nucleic acid binding#GO:0090079;binding#GO:0005488;organic cyclic compound binding#GO:0097159;translation elongation factor activity#GO:0003746;translation factor activity, RNA binding#GO:0008135 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;translational elongation#GO:0006414;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 translation elongation factor#PC00222;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000021416.1|UniProtKB=H2XTS1 H2XTS1 LOC100180822 PTHR46989:SF3 USP DOMAIN-CONTAINING PROTEIN USPA DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000002487.3|UniProtKB=F7B3X8 F7B3X8 PTHR10026:SF7 CYCLIN CYCLIN-C protein kinase regulator activity#GO:0019887;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of RNA metabolic process#GO:0051254;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;mediator complex#GO:0016592;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 kinase activator#PC00138 CIOIN|Ensembl=ENSCING00000003390.3|UniProtKB=F6TD07 F6TD07 PTHR11703:SF0 DEOXYHYPUSINE SYNTHASE DEOXYHYPUSINE SYNTHASE transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824 macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;peptidyl-amino acid modification#GO:0018193;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000004525.3|UniProtKB=F7A9H5 F7A9H5 LOC100182937 PTHR12932:SF9 P25 ALPHA-RELATED TUBULIN POLYMERIZATION-PROMOTING PROTEIN HOMOLOG cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;microtubule cytoskeleton organization#GO:0000226;protein-containing complex assembly#GO:0065003;regulation of cellular component organization#GO:0051128;cellular component organization#GO:0016043;cellular process#GO:0009987;microtubule polymerization or depolymerization#GO:0031109;positive regulation of protein polymerization#GO:0032273;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of protein-containing complex assembly#GO:0043254;microtubule polymerization#GO:0046785;microtubule-based process#GO:0007017;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;regulation of cellular component biogenesis#GO:0044087;protein-containing complex organization#GO:0043933;supramolecular fiber organization#GO:0097435;microtubule bundle formation#GO:0001578;biological regulation#GO:0065007;protein polymerization#GO:0051258;positive regulation of cellular component organization#GO:0051130;cytoskeleton organization#GO:0007010;positive regulation of cellular component biogenesis#GO:0044089;regulation of protein polymerization#GO:0032271;positive regulation of biological process#GO:0048518 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 CIOIN|Ensembl=ENSCING00000002486.3|UniProtKB=Q1RL74 Q1RL74 Ci-ZF(ZZ)-1 PTHR22705:SF0 ZINC FINGER, ZZ DOMAIN CONTAINING 3 ZZ-TYPE ZINC FINGER-CONTAINING PROTEIN 3 chromatin/chromatin-binding, or -regulatory protein#PC00077 CIOIN|Ensembl=ENSCING00000019058.1|UniProtKB=H2XKR4 H2XKR4 PTHR44942:SF4 METHYLTRANSF_11 DOMAIN-CONTAINING PROTEIN METHYLTRANSFERASE TYPE 11 DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000007320.3|UniProtKB=Q7YXB3 Q7YXB3 uglcat2 PTHR10896:SF65 GALACTOSYLGALACTOSYLXYLOSYLPROTEIN 3-BETA-GLUCURONOSYLTRANSFERASE BETA-1,3-GLUCURONYLTRANSFERASE GALACTOSYLGALACTOSYLXYLOSYLPROTEIN 3-BETA-GLUCURONOSYLTRANSFERASE 3 carbohydrate metabolic process#GO:0005975;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;primary metabolic process#GO:0044238 cytoplasm#GO:0005737;bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;Golgi membrane#GO:0000139;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111 CIOIN|Ensembl=ENSCING00000005611.3|UniProtKB=F7ATR6 F7ATR6 LOC100179368 PTHR10671:SF34 EPITHELIAL MEMBRANE PROTEIN-RELATED PROTEIN NKG7 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cytoskeletal protein#PC00085 CIOIN|Ensembl=ENSCING00000012875.2|UniProtKB=F6PYN6 F6PYN6 PTHR14882:SF1 COILED-COIL DOMAIN-CONTAINING 74A CCDC92 DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000004323.3|UniProtKB=F7BNL5 F7BNL5 LOC100176604 PTHR43108:SF16 N-ACETYLGLUCOSAMINE-6-SULFATASE FAMILY MEMBER EXTRACELLULAR SULFATASE SULF-1 HOMOLOG hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;carbohydrate derivative binding#GO:0097367;glycosaminoglycan binding#GO:0005539;binding#GO:0005488;catalytic activity#GO:0003824 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000006559.3|UniProtKB=F7AQZ5 F7AQZ5 PTHR45620:SF36 PDF RECEPTOR-LIKE PROTEIN-RELATED SUBFAMILY NOT NAMED signaling receptor activity#GO:0038023;peptide hormone binding#GO:0017046;binding#GO:0005488;peptide binding#GO:0042277;amide binding#GO:0033218;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled peptide receptor activity#GO:0008528;hormone binding#GO:0042562;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 CIOIN|Ensembl=ENSCING00000000229.3|UniProtKB=F7A1A8 F7A1A8 PTHR45643:SF16 REVERSE TRANSCRIPTASE REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN reverse transcriptase#PC00200 CIOIN|Ensembl=ENSCING00000013889.2|UniProtKB=F7BMU6 F7BMU6 PTHR22600:SF21 BETA-HEXOSAMINIDASE BETA-HEXOSAMINIDASE A hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 glycosaminoglycan metabolic process#GO:0030203;carbohydrate derivative metabolic process#GO:1901135;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;aminoglycan metabolic process#GO:0006022;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;membrane#GO:0016020 glycosidase#PC00110;metabolite interconversion enzyme#PC00262;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000004437.3|UniProtKB=F6Y3C0 F6Y3C0 PTHR10071:SF281 TRANSCRIPTION FACTOR GATA FAMILY MEMBER BOX A-BINDING FACTOR-RELATED sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of nitrogen compound metabolic process#GO:0051173;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;positive regulation of RNA biosynthetic process#GO:1902680;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;positive regulation of biological process#GO:0048518;negative regulation of cellular process#GO:0048523;negative regulation of biosynthetic process#GO:0009890;regulation of DNA-templated transcription#GO:0006355;negative regulation of metabolic process#GO:0009892;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;negative regulation of nitrogen compound metabolic process#GO:0051172;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;positive regulation of RNA metabolic process#GO:0051254;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218 CIOIN|Ensembl=ENSCING00000002007.3|UniProtKB=F6WT77 F6WT77 LOC100183869 PTHR34721:SF3 PROTEIN CBG09734 ACTIVIN_RECP DOMAIN-CONTAINING PROTEIN-RELATED CIOIN|Ensembl=ENSCING00000006637.3|UniProtKB=F6U0P5 F6U0P5 PTHR11596:SF94 ALKALINE PHOSPHATASE ALKALINE PHOSPHATASE hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 cellular metabolic process#GO:0044237;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;dephosphorylation#GO:0016311;metabolic process#GO:0008152 phosphatase#PC00181;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000007115.3|UniProtKB=F6S9Y0 F6S9Y0 LOC100183543 PTHR43725:SF47 UDP-GLUCOSE 4-EPIMERASE UDP-GLUCOSE 4-EPIMERASE racemase and epimerase activity, acting on carbohydrates and derivatives#GO:0016857;isomerase activity#GO:0016853;catalytic activity#GO:0003824 monosaccharide metabolic process#GO:0005996;carbohydrate metabolic process#GO:0005975;organic substance metabolic process#GO:0071704;primary metabolic process#GO:0044238;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 epimerase/racemase#PC00096;metabolite interconversion enzyme#PC00262 Fructose galactose metabolism#P02744>UDP Glucose 4 epimerase#P02965 CIOIN|Ensembl=ENSCING00000014147.2|UniProtKB=F7ARN8 F7ARN8 LOC100187147 PTHR12469:SF2 PROTEIN EMI5 HOMOLOG, MITOCHONDRIAL SUCCINATE DEHYDROGENASE ASSEMBLY FACTOR 2, MITOCHONDRIAL cellular component biogenesis#GO:0044085;mitochondrial respiratory chain complex assembly#GO:0033108;macromolecule modification#GO:0043412;aerobic electron transport chain#GO:0019646;protein-containing complex assembly#GO:0065003;protein modification process#GO:0036211;electron transport chain#GO:0022900;ATP synthesis coupled electron transport#GO:0042773;energy derivation by oxidation of organic compounds#GO:0015980;tricarboxylic acid cycle#GO:0006099;nitrogen compound metabolic process#GO:0006807;respiratory electron transport chain#GO:0022904;mitochondrion organization#GO:0007005;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular component assembly#GO:0022607;cellular respiration#GO:0045333;aerobic respiration#GO:0009060;macromolecule metabolic process#GO:0043170;generation of precursor metabolites and energy#GO:0006091;cellular metabolic process#GO:0044237;organonitrogen compound metabolic process#GO:1901564;cellular component organization#GO:0016043;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;mitochondrial ATP synthesis coupled electron transport#GO:0042775;mitochondrial respiratory chain complex II assembly#GO:0034553;protein-containing complex organization#GO:0043933;organelle organization#GO:0006996;oxidative phosphorylation#GO:0006119;mitochondrial electron transport, succinate to ubiquinone#GO:0006121 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000022360.1|UniProtKB=F6SZU4 F6SZU4 PTHR43272:SF107 LONG-CHAIN-FATTY-ACID--COA LIGASE LONG-CHAIN-FATTY-ACID--COA LIGASE 5 long-chain fatty acid-CoA ligase activity#GO:0004467;ligase activity#GO:0016874;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ligase#PC00142;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000004581.3|UniProtKB=F6WQD2 F6WQD2 LOC100186372 PTHR11805:SF1 CYSTEINE-RICH PDZ-BINDING PROTEIN CYSTEINE-RICH PDZ-BINDING PROTEIN cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;microtubule binding#GO:0008017;tubulin binding#GO:0015631;binding#GO:0005488 cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;microtubule cytoskeleton organization#GO:0000226;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cellular process#GO:0009987;cytoplasmic microtubule organization#GO:0031122 CIOIN|Ensembl=ENSCING00000011981.2|UniProtKB=F6RXN1 F6RXN1 PTHR10877:SF150 POLYCYSTIN FAMILY MEMBER REJ DOMAIN-CONTAINING PROTEIN calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;metal ion transmembrane transporter activity#GO:0046873;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267;monoatomic ion channel activity#GO:0005216 detection of stimulus#GO:0051606;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;detection of mechanical stimulus#GO:0050982;response to mechanical stimulus#GO:0009612;response to abiotic stimulus#GO:0009628 cellular anatomical entity#GO:0110165;membrane#GO:0016020 ion channel#PC00133;transporter#PC00227 CIOIN|Ensembl=ENSCING00000008215.4|UniProtKB=Q1RPW7 Q1RPW7 Ci-ZF(CCHC)-20 PTHR47958:SF103 ATP-DEPENDENT RNA HELICASE DBP3 ATP-DEPENDENT RNA HELICASE DDX41-RELATED catalytic activity, acting on RNA#GO:0140098;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;helicase activity#GO:0004386;ATP-dependent activity#GO:0140657;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;catalytic activity, acting on a nucleic acid#GO:0140640;mRNA binding#GO:0003729 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;mRNA splicing, via spliceosome#GO:0000398;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA helicase#PC00032 CIOIN|Ensembl=ENSCING00000022847.1|UniProtKB=H2Y212 H2Y212 PTHR24064:SF577 SOLUTE CARRIER FAMILY 22 MEMBER GH09241P secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000002295.3|UniProtKB=F6URF6 F6URF6 tef_hlf PTHR11988:SF27 THYROTROPH EMBRYONIC FACTOR RELATED GH27708P sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 DNA-binding transcription factor#PC00218;basic leucine zipper transcription factor#PC00056 CIOIN|Ensembl=ENSCING00000023023.1|UniProtKB=H2Y0K7 H2Y0K7 LOC100180797 PTHR24243:SF234 G-PROTEIN COUPLED RECEPTOR GROWTH HORMONE SECRETAGOGUE RECEPTOR TYPE 1-LIKE signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 CIOIN|Ensembl=ENSCING00000006095.3|UniProtKB=F6YX67 F6YX67 LOC100183602 PTHR10953:SF6 UBIQUITIN-ACTIVATING ENZYME E1 NEDD8-ACTIVATING ENZYME E1 CATALYTIC SUBUNIT ligase activity#GO:0016874;transferase activity#GO:0016740;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877;nucleotidyltransferase activity#GO:0016779;thiosulfate sulfurtransferase activity#GO:0004792;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity, acting on a protein#GO:0140096;sulfurtransferase activity#GO:0016783 protein neddylation#GO:0045116;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;post-translational protein modification#GO:0043687;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 Ubiquitin proteasome pathway#P00060>E1#P01492 CIOIN|Ensembl=ENSCING00000013188.2|UniProtKB=Q4H2X6 Q4H2X6 Ci-PPAR PTHR24082:SF497 NUCLEAR HORMONE RECEPTOR PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA-LIKE cis-regulatory region sequence-specific DNA binding#GO:0000987;signaling receptor activity#GO:0038023;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular transducer activity#GO:0060089;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;hormone-mediated signaling pathway#GO:0009755;regulation of biological process#GO:0050789;cellular response to hormone stimulus#GO:0032870;negative regulation of DNA-templated transcription#GO:0045892;positive regulation of biological process#GO:0048518;cellular developmental process#GO:0048869;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;negative regulation of metabolic process#GO:0009892;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of nitrogen compound metabolic process#GO:0051172;positive regulation of cellular process#GO:0048522;regulation of cellular process#GO:0050794;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of lipid metabolic process#GO:0019216;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;negative regulation of cellular metabolic process#GO:0031324;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;positive regulation of RNA biosynthetic process#GO:1902680;negative regulation of RNA biosynthetic process#GO:1902679;developmental process#GO:0032502;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of biosynthetic process#GO:0009891;cell differentiation#GO:0030154;response to endogenous stimulus#GO:0009719;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;negative regulation of biosynthetic process#GO:0009890;regulation of DNA-templated transcription#GO:0006355;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;response to stimulus#GO:0050896;regulation of cellular biosynthetic process#GO:0031326;response to hormone#GO:0009725;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;positive regulation of RNA metabolic process#GO:0051254 C4 zinc finger nuclear receptor#PC00169;zinc finger transcription factor#PC00244 CIOIN|Ensembl=ENSCING00000009111.3|UniProtKB=F6Q8Z9 F6Q8Z9 LOC100177228 PTHR23259:SF70 RIDDLE ACCESSORY GLAND PROTEIN ACP62F-RELATED protease inhibitor#PC00191;protein-binding activity modulator#PC00095 CIOIN|Ensembl=ENSCING00000008076.3|UniProtKB=F6Z6Y7 F6Z6Y7 LOC100184767 PTHR11699:SF190 ALDEHYDE DEHYDROGENASE-RELATED 10-FORMYLTETRAHYDROFOLATE DEHYDROGENASE oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 dehydrogenase#PC00092;oxidoreductase#PC00176 5-Hydroxytryptamine degredation#P04372>Aldehyde Dehydrogenase#P04402 CIOIN|Ensembl=ENSCING00000007056.3|UniProtKB=F6WWH2 F6WWH2 PTHR21426:SF12 EXOCYST COMPLEX COMPONENT 8 EXOCYST COMPLEX COMPONENT 8 localization#GO:0051179;localization within membrane#GO:0051668;cellular localization#GO:0051641;vesicle-mediated transport to the plasma membrane#GO:0098876;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;post-Golgi vesicle-mediated transport#GO:0006892;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;Golgi to plasma membrane transport#GO:0006893;protein localization#GO:0008104 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;vesicle tethering complex#GO:0099023;exocyst#GO:0000145;cell cortex#GO:0005938;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000024084.1|UniProtKB=A0A1W3JL17 A0A1W3JL17 zf(cchc)-17 PTHR46109:SF1 PROTEIN LIN-28 PROTEIN LIN-28 HOMOLOG nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;RNA metabolic process#GO:0016070;regulatory ncRNA processing#GO:0070918;RNA processing#GO:0006396;gene expression#GO:0010467;pre-miRNA processing#GO:0031054;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulatory ncRNA-mediated gene silencing#GO:0031047;miRNA processing#GO:0035196;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000006260.3|UniProtKB=F6VPU4 F6VPU4 LOC100176842 PTHR31559:SF0 PYRIDOXAL 5'-PHOSPHATE SYNTHASE SUBUNIT SNO PYRIDOXAL 5'-PHOSPHATE SYNTHASE SUBUNIT SNO1-RELATED hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;organic hydroxy compound metabolic process#GO:1901615;heterocycle metabolic process#GO:0046483;organophosphate biosynthetic process#GO:0090407;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic hydroxy compound biosynthetic process#GO:1901617;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;heterocycle biosynthetic process#GO:0018130;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;pyridine-containing compound metabolic process#GO:0072524;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;small molecule biosynthetic process#GO:0044283;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622 lyase#PC00144 CIOIN|Ensembl=ENSCING00000006702.3|UniProtKB=F7ARU3 F7ARU3 PTHR16317:SF1 INTEGRIN ALPHA REPEAT DOMAIN-CONTAINING KICSTOR COMPLEX PROTEIN ITFG2 regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;regulation of signaling#GO:0023051;biological regulation#GO:0065007;regulation of intracellular signal transduction#GO:1902531;regulation of TOR signaling#GO:0032006 protein-containing complex#GO:0032991 cell adhesion molecule#PC00069;integrin#PC00126 CIOIN|Ensembl=ENSCING00000023327.1|UniProtKB=H2XPB8 H2XPB8 LOC104266462 PTHR11711:SF30 ADP RIBOSYLATION FACTOR-RELATED ADP-RIBOSYLATION FACTOR 1 carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;anion binding#GO:0043168 cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 G-protein#PC00020 Integrin signalling pathway#P00034>Arf1#P00923;Huntington disease#P00029>ARF#P00786 CIOIN|Ensembl=ENSCING00000023359.1|UniProtKB=H2XQL4 H2XQL4 PTHR11984:SF53 CONNEXIN GAP JUNCTION PROTEIN wide pore channel activity#GO:0022829;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;channel activity#GO:0015267 biological regulation#GO:0065007;regulation of biological process#GO:0050789;cell communication#GO:0007154;cellular process#GO:0009987;cell-cell signaling#GO:0007267;signaling#GO:0023052 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 cell junction protein#PC00070;gap junction#PC00105 CIOIN|Ensembl=ENSCING00000013268.2|UniProtKB=F7BMF5 F7BMF5 LOC100179826 PTHR28643:SF1 SWI5-DEPENDENT RECOMBINATION DNA REPAIR PROTEIN 1 HOMOLOG SWI5-DEPENDENT RECOMBINATION DNA REPAIR PROTEIN 1 HOMOLOG transcription coactivator activity#GO:0003713;nuclear receptor coactivator activity#GO:0030374;molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;protein-macromolecule adaptor activity#GO:0030674 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;positive regulation of nitrogen compound metabolic process#GO:0051173;double-strand break repair#GO:0006302;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;DNA damage response#GO:0006974;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;recombinational repair#GO:0000725;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;regulation of DNA-templated transcription#GO:0006355;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;positive regulation of cellular biosynthetic process#GO:0031328;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;double-strand break repair via homologous recombination#GO:0000724;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;positive regulation of RNA metabolic process#GO:0051254;cellular response to stress#GO:0033554;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;DNA metabolic process#GO:0006259 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-DNA complex#GO:0032993;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 DNA metabolism protein#PC00009 CIOIN|Ensembl=ENSCING00000018321.1|UniProtKB=H2XKK4 H2XKK4 PTHR22588:SF3 VWFA DOMAIN-CONTAINING PROTEIN VWFA DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000003771.3|UniProtKB=F6TIX8 F6TIX8 PTHR11339:SF414 EXTRACELLULAR MATRIX GLYCOPROTEIN RELATED VON WILLEBRAND FACTOR-LIKE extracellular matrix protein#PC00102 CIOIN|Ensembl=ENSCING00000022812.1|UniProtKB=H2XPY6 H2XPY6 PTHR24343:SF299 SERINE/THREONINE KINASE SERINE_THREONINE-PROTEIN KINASE KIN-29 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;nitrogen compound metabolic process#GO:0006807;biological regulation#GO:0065007;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000001274.3|UniProtKB=F6ZVS4 F6ZVS4 LOC100181785 PTHR12867:SF6 GLYCOSYL TRANSFERASE-RELATED N-ACETYLGLUCOSAMINYLDIPHOSPHODOLICHOL N-ACETYLGLUCOSAMINYLTRANSFERASE transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000007838.3|UniProtKB=F6WSZ0 F6WSZ0 LOC100180438 PTHR14289:SF16 F-BOX ONLY PROTEIN 3 POLYMERASE DELTA-INTERACTING PROTEIN 2 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;postreplication repair#GO:0006301;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;translesion synthesis#GO:0019985;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;nucleobase-containing compound biosynthetic process#GO:0034654;DNA biosynthetic process#GO:0071897;DNA synthesis involved in DNA repair#GO:0000731;aromatic compound biosynthetic process#GO:0019438;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259 CIOIN|Ensembl=ENSCING00000001965.3|UniProtKB=F6XSZ3 F6XSZ3 LOC100183528 PTHR10671:SF108 EPITHELIAL MEMBRANE PROTEIN-RELATED CLAUDIN FAMILY PROTEIN-RELATED cytoskeletal protein#PC00085 CIOIN|Ensembl=ENSCING00000019290.1|UniProtKB=H2XNY2 H2XNY2 PTHR31489:SF2 LIN52 FAMILY MEMBER PROTEIN LIN-52 HOMOLOG CIOIN|Ensembl=ENSCING00000008692.3|UniProtKB=F6WZV6 F6WZV6 PTHR45689:SF5 I[[H]] CHANNEL, ISOFORM E I[[H]] CHANNEL, ISOFORM E monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated potassium channel activity#GO:0005249;channel activity#GO:0015267;transporter activity#GO:0005215;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;regulation of membrane potential#GO:0042391;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;localization#GO:0051179;regulation of biological process#GO:0050789;sodium ion transport#GO:0006814;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;regulation of cellular process#GO:0050794;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;regulation of membrane depolarization#GO:0003254;sodium ion transmembrane transport#GO:0035725;potassium ion transport#GO:0006813 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;voltage-gated potassium channel complex#GO:0008076;cation channel complex#GO:0034703;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 CIOIN|Ensembl=ENSCING00000021730.1|UniProtKB=H2Y2U9 H2Y2U9 PTHR24170:SF2 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 27 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 27 nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;binding#GO:0005488;molecular function regulator activity#GO:0098772;protein binding#GO:0005515;SNARE binding#GO:0000149;enzyme regulator activity#GO:0030234;guanyl-nucleotide exchange factor activity#GO:0005085 endosomal transport#GO:0016197;cellular localization#GO:0051641;neurogenesis#GO:0022008;cell projection organization#GO:0030030;transport#GO:0006810;developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cellular anatomical entity morphogenesis#GO:0032989;system development#GO:0048731;cell differentiation#GO:0030154;establishment of localization#GO:0051234;anatomical structure morphogenesis#GO:0009653;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell morphogenesis#GO:0000902;cellular process#GO:0009987;cell development#GO:0048468;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;anatomical structure development#GO:0048856;establishment of localization in cell#GO:0051649;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;intracellular transport#GO:0046907;generation of neurons#GO:0048699;early endosome to late endosome transport#GO:0045022 endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;early endosome#GO:0005769;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;neuron projection#GO:0043005;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;transport vesicle#GO:0030133;cell projection#GO:0042995;late endosome#GO:0005770;plasma membrane#GO:0005886 CIOIN|Ensembl=ENSCING00000014329.2|UniProtKB=F6TZL5 F6TZL5 LOC100187103 PTHR19282:SF456 TETRASPANIN CD63 MOLECULE cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000015664.2|UniProtKB=F6X505 F6X505 LOC100187111 PTHR28434:SF1 PROTEIN C3ORF33 PROTEIN C3ORF33 CIOIN|Ensembl=ENSCING00000014109.2|UniProtKB=F6TCR0 F6TCR0 PTHR11042:SF187 EUKARYOTIC TRANSLATION INITIATION FACTOR 2-ALPHA KINASE EIF2-ALPHA KINASE -RELATED EUKARYOTIC TRANSLATION INITIATION FACTOR 2-ALPHA KINASE 2 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of protein metabolic process#GO:0051246;regulation of amide metabolic process#GO:0034248;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;protein modification process#GO:0036211;regulation of translational initiation#GO:0006446;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;phosphorylation#GO:0016310;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cellular process#GO:0009987;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;response to stress#GO:0006950;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;post-transcriptional regulation of gene expression#GO:0010608;biological regulation#GO:0065007;regulation of translation#GO:0006417;cellular response to stress#GO:0033554;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000024322.1|UniProtKB=H2XT36 H2XT36 LOC100181245 PTHR45694:SF18 GLUTAREDOXIN 2 GLUTAREDOXIN-1-RELATED disulfide oxidoreductase activity#GO:0015036;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;response to stress#GO:0006950;cellular response to chemical stimulus#GO:0070887;response to chemical#GO:0042221;cellular response to oxidative stress#GO:0034599;response to oxidative stress#GO:0006979;cellular response to stress#GO:0033554;cellular process#GO:0009987 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000025075.1|UniProtKB=H2Y123 H2Y123 LOC100177698 PTHR10778:SF13 SOLUTE CARRIER FAMILY 35 MEMBER B ADENOSINE 3'-PHOSPHO 5'-PHOSPHOSULFATE TRANSPORTER 1 carbohydrate derivative transmembrane transporter activity#GO:1901505;purine nucleotide transmembrane transporter activity#GO:0015216;nucleobase-containing compound transmembrane transporter activity#GO:0015932;transmembrane transporter activity#GO:0022857;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215 localization#GO:0051179;organic substance transport#GO:0071702;organophosphate ester transport#GO:0015748;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;organic anion transport#GO:0015711;nucleobase-containing compound transport#GO:0015931;transport#GO:0006810;nitrogen compound transport#GO:0071705;cellular process#GO:0009987;carbohydrate derivative transport#GO:1901264 bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;Golgi membrane#GO:0000139;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000003566.3|UniProtKB=F6YSI6 F6YSI6 PTHR10924:SF4 MAJOR FACILITATOR SUPERFAMILY PROTEIN-RELATED GH15861P tetrapyrrole binding#GO:0046906;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;binding#GO:0005488;organic cyclic compound binding#GO:0097159;heme binding#GO:0020037 localization#GO:0051179;organic substance transport#GO:0071702;metal ion transport#GO:0030001;establishment of localization#GO:0051234;transport#GO:0006810;monoatomic cation transport#GO:0006812;nitrogen compound transport#GO:0071705;iron ion transport#GO:0006826;transition metal ion transport#GO:0000041;monoatomic ion transport#GO:0006811 cellular anatomical entity#GO:0110165;membrane#GO:0016020 secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000018805.1|UniProtKB=H2Y1W5 H2Y1W5 PTHR13467:SF3 CUE DOMAIN CONTAINING PROTEIN 1 CUE DOMAIN-CONTAINING PROTEIN 1 CIOIN|Ensembl=ENSCING00000014705.2|UniProtKB=F6ZC63 F6ZC63 PTHR24246:SF27 OLFACTORY RECEPTOR AND ADENOSINE RECEPTOR ADENOSINE RECEPTOR, ISOFORM A G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711 CIOIN|Ensembl=ENSCING00000002612.3|UniProtKB=F7B314 F7B314 PTHR16011:SF0 IFT57/HIPPI INTRAFLAGELLAR TRANSPORT PROTEIN 57 HOMOLOG non-motile cilium assembly#GO:1905515;cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;cilium assembly#GO:0060271;cell projection organization#GO:0030030;transport#GO:0006810;microtubule-based movement#GO:0007018;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;transport along microtubule#GO:0010970;cell projection assembly#GO:0030031;intraciliary transport#GO:0042073;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based transport#GO:0099111;microtubule-based process#GO:0007017;establishment of localization#GO:0051234;organelle organization#GO:0006996;cytoskeleton-dependent intracellular transport#GO:0030705;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;protein-containing complex localization#GO:0031503 microtubule organizing center#GO:0005815;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intraciliary transport particle B#GO:0030992;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;cell projection#GO:0042995;cilium#GO:0005929;intraciliary transport particle#GO:0030990 structural protein#PC00211 Huntington disease#P00029>Hip-12#P00763;Huntington disease#P00029>Hippi#P00794 CIOIN|Ensembl=ENSCING00000024373.1|UniProtKB=H2Y2G4 H2Y2G4 LOC100182535 PTHR12243:SF60 MADF DOMAIN TRANSCRIPTION FACTOR SI:CH211-15D5.12-RELATED regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218 CIOIN|Ensembl=ENSCING00000003359.3|UniProtKB=F6S0N6 F6S0N6 PTHR23088:SF27 NITRILASE-RELATED DEAMINATED GLUTATHIONE AMIDASE metabolite interconversion enzyme#PC00262;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000024359.1|UniProtKB=H2XNA6 H2XNA6 LOC100183989 PTHR19282:SF534 TETRASPANIN TETRASPANIN FAMILY-RELATED cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000004357.3|UniProtKB=F6S5Z8 F6S5Z8 PTHR11475:SF144 OXIDASE/PEROXIDASE NAD(P)H OXIDASE (H2O2-FORMING) oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;antioxidant activity#GO:0016209;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 peroxidase#PC00180;metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000006949.3|UniProtKB=F6VN18 F6VN18 PTHR24033:SF224 EGF-LIKE DOMAIN-CONTAINING PROTEIN C-TYPE LECTIN CIOIN|Ensembl=ENSCING00000023012.1|UniProtKB=Q1RL38 Q1RL38 Ci-ZF(C2H2)-151 PTHR46179:SF26 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 423 HOMOLOG regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 CIOIN|Ensembl=ENSCING00000015675.2|UniProtKB=A0A1W2WL76 A0A1W2WL76 LOC101243376 PTHR10791:SF112 RAG1-ACTIVATING PROTEIN 1 SUGAR TRANSPORTER SWEET1 transmembrane transporter activity#GO:0022857;sugar transmembrane transporter activity#GO:0051119;transporter activity#GO:0005215;carbohydrate transmembrane transporter activity#GO:0015144 localization#GO:0051179;organic substance transport#GO:0071702;establishment of localization#GO:0051234;carbohydrate transport#GO:0008643;transport#GO:0006810 cellular anatomical entity#GO:0110165;membrane#GO:0016020 CIOIN|Ensembl=ENSCING00000015466.2|UniProtKB=F6TWK8 F6TWK8 LOC100175568 PTHR24412:SF463 KELCH PROTEIN KELCH-LIKE PROTEIN 40A scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000009305.3|UniProtKB=F7A6E1 F7A6E1 PTHR43243:SF105 INNER MEMBRANE TRANSPORTER YGJI-RELATED CATIONIC AMINO ACID TRANSPORTER C-TERMINAL DOMAIN-CONTAINING PROTEIN transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;amino acid transmembrane transporter activity#GO:0015171;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215;organic acid transmembrane transporter activity#GO:0005342 localization#GO:0051179;organic substance transport#GO:0071702;establishment of localization#GO:0051234;amino acid transport#GO:0006865;organic anion transport#GO:0015711;organic acid transport#GO:0015849;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 amino acid transporter#PC00046;transporter#PC00227 CIOIN|Ensembl=ENSCING00000004451.3|UniProtKB=F6UT38 F6UT38 PTHR15735:SF21 FCH AND DOUBLE SH3 DOMAINS PROTEIN PROTEIN NERVOUS WRECK cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165 CIOIN|Ensembl=ENSCING00000019739.1|UniProtKB=H2XYT9 H2XYT9 PTHR24230:SF75 G-PROTEIN COUPLED RECEPTOR RELAXIN FAMILY PEPTIDE RECEPTOR 3 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;neuropeptide signaling pathway#GO:0007218;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 CIOIN|Ensembl=ENSCING00000002025.3|UniProtKB=F6YA02 F6YA02 LOC100184654 PTHR11743:SF70 VOLTAGE-DEPENDENT ANION-SELECTIVE CHANNEL GH26960P-RELATED voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;voltage-gated channel activity#GO:0022832;gated channel activity#GO:0022836;monoatomic anion transmembrane transporter activity#GO:0008509;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267;monoatomic ion channel activity#GO:0005216 envelope#GO:0031975;bounding membrane of organelle#GO:0098588;mitochondrial membrane#GO:0031966;intracellular membrane-bounded organelle#GO:0043231;mitochondrial outer membrane#GO:0005741;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867 ion channel#PC00133;transporter#PC00227;voltage-gated ion channel#PC00241 CIOIN|Ensembl=ENSCING00000006761.3|UniProtKB=F6XBS5 F6XBS5 PTHR11889:SF31 HEDGEHOG PROTEIN HEDGEHOG intercellular signal molecule#PC00207 Hedgehog signaling pathway#P00025>Hedgehog#P00688 CIOIN|Ensembl=ENSCING00000007118.3|UniProtKB=F6SWC9 F6SWC9 PTHR11610:SF173 LIPASE LIPASE DOMAIN-CONTAINING PROTEIN-RELATED hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;lipid catabolic process#GO:0016042;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;primary metabolic process#GO:0044238 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 lipase#PC00143;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000024790.1|UniProtKB=Q4H2P0 Q4H2P0 Ci-TF4 PTHR15741:SF25 BASIC HELIX-LOOP-HELIX ZIP TRANSCRIPTION FACTOR MAX-LIKE PROTEIN X sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218 CIOIN|Ensembl=ENSCING00000008193.3|UniProtKB=F6PND8 F6PND8 PTHR20766:SF3 LARGE NEUTRAL AMINO ACIDS TRANSPORTER SMALL SUBUNIT 4-LIKE ISOFORM X1 LARGE NEUTRAL AMINO ACIDS TRANSPORTER SMALL SUBUNIT 4-LIKE ISOFORM X1 transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;organic acid transmembrane transporter activity#GO:0005342;L-amino acid transmembrane transporter activity#GO:0015179;organic anion transmembrane transporter activity#GO:0008514;amino acid transmembrane transporter activity#GO:0015171;neutral L-amino acid transmembrane transporter activity#GO:0015175;transporter activity#GO:0005215 localization#GO:0051179;neutral amino acid transport#GO:0015804;organic substance transport#GO:0071702;establishment of localization#GO:0051234;amino acid transport#GO:0006865;organic anion transport#GO:0015711;organic acid transport#GO:0015849;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942 CIOIN|Ensembl=ENSCING00000022977.1|UniProtKB=H2XQ94 H2XQ94 LOC100183571 PTHR33768:SF3 MIP11318P MIP11318P CIOIN|Ensembl=ENSCING00000006758.3|UniProtKB=F6XZF9 F6XZF9 PTHR11616:SF309 SODIUM/CHLORIDE DEPENDENT TRANSPORTER TRANSPORTER metal ion transport#GO:0030001;transmembrane transport#GO:0055085;amino acid transport#GO:0006865;organic anion transport#GO:0015711;organic acid transport#GO:0015849;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;localization#GO:0051179;organic substance transport#GO:0071702;sodium ion transport#GO:0006814;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;sodium ion transmembrane transport#GO:0035725 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 primary active transporter#PC00068;transporter#PC00227 CIOIN|Ensembl=ENSCING00000004187.3|UniProtKB=F7B5K2 F7B5K2 PTHR45774:SF4 BTB/POZ DOMAIN-CONTAINING AXUNDEAD, ISOFORM F cell differentiation#GO:0030154;cellular developmental process#GO:0048869;system development#GO:0048731;neurogenesis#GO:0022008;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;developmental process#GO:0032502;multicellular organismal process#GO:0032501;cellular process#GO:0009987;nervous system development#GO:0007399 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000003486.3|UniProtKB=F6UA18 F6UA18 PTHR12760:SF0 TETRATRICOPEPTIDE REPEAT PROTEIN ER MEMBRANE PROTEIN COMPLEX SUBUNIT 2 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein folding#GO:0006457;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane protein complex#GO:0098796;endoplasmic reticulum protein-containing complex#GO:0140534;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;EMC complex#GO:0072546;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 chaperone#PC00072 CIOIN|Ensembl=ENSCING00000002325.4|UniProtKB=F7AZI8 F7AZI8 LOC100182642 PTHR24056:SF0 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE 7 transferase activity#GO:0016740;cyclin-dependent protein kinase activity#GO:0097472;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;cyclin-dependent protein serine/threonine kinase activity#GO:0004693;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of transcription by RNA polymerase II#GO:0045944;protein modification process#GO:0036211;regulation of RNA biosynthetic process#GO:2001141;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;phosphorylation#GO:0016310;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of DNA-templated transcription#GO:0006355;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;positive regulation of RNA metabolic process#GO:0051254;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;DNA-directed RNA polymerase complex#GO:0000428;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nucleoplasm#GO:0005654;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;serine/threonine protein kinase complex#GO:1902554;RNA polymerase II transcription regulator complex#GO:0090575;protein kinase complex#GO:1902911;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;RNA polymerase II, holoenzyme#GO:0016591;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;transcription regulator complex#GO:0005667;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;transcription factor TFIIH holo complex#GO:0005675;nuclear protein-containing complex#GO:0140513 non-receptor serine/threonine protein kinase#PC00167 CIOIN|Ensembl=ENSCING00000002536.3|UniProtKB=F6X2D1 F6X2D1 LOC100177512 PTHR45630:SF8 CATION-TRANSPORTING ATPASE-RELATED CATION-TRANSPORTING ATPASE transmembrane transporter activity#GO:0022857;primary active transmembrane transporter activity#GO:0015399;ATP-dependent activity#GO:0140657;active monoatomic ion transmembrane transporter activity#GO:0022853;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;ATPase-coupled transmembrane transporter activity#GO:0042626;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation transmembrane transporter activity#GO:0008324 localization#GO:0051179;cellular process#GO:0009987;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810 cellular anatomical entity#GO:0110165;membrane#GO:0016020 primary active transporter#PC00068;transporter#PC00227 CIOIN|Ensembl=ENSCING00000000868.3|UniProtKB=F6QVV8 F6QVV8 LOC494399 PTHR16146:SF46 INTELECTIN INTELECTIN-1A-RELATED CIOIN|Ensembl=ENSCING00000013269.1|UniProtKB=F7BME9 F7BME9 LOC100175152 PTHR46981:SF1 BIS(5'-ADENOSYL)-TRIPHOSPHATASE BIS(5'-ADENOSYL)-TRIPHOSPHATASE pyrophosphatase activity#GO:0016462;binding#GO:0005488;catalytic activity#GO:0003824;ubiquitin-like protein ligase binding#GO:0044389;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;enzyme binding#GO:0019899;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;ubiquitin protein ligase binding#GO:0031625 negative regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032435;regulation of protein metabolic process#GO:0051246;regulation of catabolic process#GO:0009894;heterocycle catabolic process#GO:0046700;regulation of nitrogen compound metabolic process#GO:0051171;regulation of proteolysis involved in protein catabolic process#GO:1903050;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;apoptotic process#GO:0006915;purine-containing compound metabolic process#GO:0072521;intracellular signal transduction#GO:0035556;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;intrinsic apoptotic signaling pathway by p53 class mediator#GO:0072332;nucleoside phosphate catabolic process#GO:1901292;cellular metabolic process#GO:0044237;nucleotide catabolic process#GO:0009166;programmed cell death#GO:0012501;negative regulation of metabolic process#GO:0009892;cell communication#GO:0007154;negative regulation of protein metabolic process#GO:0051248;negative regulation of proteolysis#GO:0045861;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;organophosphate catabolic process#GO:0046434;intrinsic apoptotic signaling pathway#GO:0097193;apoptotic signaling pathway#GO:0097190;regulation of cellular process#GO:0050794;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;negative regulation of proteolysis involved in protein catabolic process#GO:1903051;nucleotide metabolic process#GO:0009117;regulation of metabolic process#GO:0019222;small molecule metabolic process#GO:0044281;cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;negative regulation of protein catabolic process#GO:0042177;regulation of protein catabolic process#GO:0042176;signal transduction by p53 class mediator#GO:0072331;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;cellular nitrogen compound catabolic process#GO:0044270;negative regulation of proteasomal protein catabolic process#GO:1901799;organic cyclic compound metabolic process#GO:1901360;cell death#GO:0008219;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;signaling#GO:0023052;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;heterocycle metabolic process#GO:0046483;regulation of proteolysis#GO:0030162;cellular response to stimulus#GO:0051716;organonitrogen compound metabolic process#GO:1901564;cellular process#GO:0009987;regulation of proteasomal protein catabolic process#GO:0061136;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;aromatic compound catabolic process#GO:0019439;negative regulation of catabolic process#GO:0009895;regulation of macromolecule metabolic process#GO:0060255;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434;nucleobase-containing small molecule metabolic process#GO:0055086 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 metabolite interconversion enzyme#PC00262;phosphatase#PC00181 CIOIN|Ensembl=ENSCING00000021029.1|UniProtKB=H2XWW0 H2XWW0 PTHR12951:SF1 RETINAL PROTEIN 4 PROTEIN UNC-119 HOMOLOG lipid binding#GO:0008289;binding#GO:0005488 cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;cilium assembly#GO:0060271;cell projection organization#GO:0030030;macromolecule localization#GO:0033036;transport#GO:0006810;nitrogen compound transport#GO:0071705;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;cell projection assembly#GO:0030031;protein localization#GO:0008104;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;organelle organization#GO:0006996;protein transport#GO:0015031;plasma membrane bounded cell projection assembly#GO:0120031 membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;organelle#GO:0043226;cilium#GO:0005929;plasma membrane bounded cell projection#GO:0120025 membrane traffic protein#PC00150 CIOIN|Ensembl=ENSCING00000018724.1|UniProtKB=H2XTH1 H2XTH1 PTHR21064:SF1 AMINOGLYCOSIDE PHOSPHOTRANSFERASE DOMAIN-CONTAINING PROTEIN-RELATED HYDROXYLYSINE KINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301 CIOIN|Ensembl=ENSCING00000010007.3|UniProtKB=F6QM49 F6QM49 LOC100178438 PTHR10671:SF108 EPITHELIAL MEMBRANE PROTEIN-RELATED CLAUDIN FAMILY PROTEIN-RELATED cytoskeletal protein#PC00085 CIOIN|Ensembl=ENSCING00000013297.1|UniProtKB=F6VVC7 F6VVC7 PTHR23503:SF132 SOLUTE CARRIER FAMILY 2 SOLUTE CARRIER FAMILY 2, FACILITATED GLUCOSE TRANSPORTER MEMBER 5-LIKE transmembrane transporter activity#GO:0022857;sugar transmembrane transporter activity#GO:0051119;transporter activity#GO:0005215;carbohydrate transmembrane transporter activity#GO:0015144 localization#GO:0051179;organic substance transport#GO:0071702;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;organic anion transport#GO:0015711;transport#GO:0006810;vitamin transport#GO:0051180;glucose transmembrane transport#GO:1904659;cellular process#GO:0009987;carbohydrate transmembrane transport#GO:0034219;carbohydrate transport#GO:0008643 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000015047.2|UniProtKB=F6S8K9 F6S8K9 LOC100186373 PTHR10177:SF527 CYCLINS CYCLIN D, ISOFORM D protein kinase regulator activity#GO:0019887;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;enzyme regulator activity#GO:0030234 regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;mitotic cell cycle phase transition#GO:0044772;regulation of nitrogen compound metabolic process#GO:0051171;cell cycle G1/S phase transition#GO:0044843;cell cycle process#GO:0022402;positive regulation of cell cycle#GO:0045787;positive regulation of cell cycle G1/S phase transition#GO:1902808;regulation of catalytic activity#GO:0050790;mitotic cell cycle process#GO:1903047;G1/S transition of mitotic cell cycle#GO:0000082;regulation of phosphorus metabolic process#GO:0051174;regulation of biological process#GO:0050789;mitotic cell cycle#GO:0000278;regulation of molecular function#GO:0065009;positive regulation of cell cycle process#GO:0090068;positive regulation of mitotic cell cycle#GO:0045931;regulation of protein serine/threonine kinase activity#GO:0071900;regulation of G1/S transition of mitotic cell cycle#GO:2000045;positive regulation of biological process#GO:0048518;regulation of cyclin-dependent protein serine/threonine kinase activity#GO:0000079;regulation of kinase activity#GO:0043549;regulation of protein kinase activity#GO:0045859;regulation of mitotic cell cycle phase transition#GO:1901990;regulation of cell cycle phase transition#GO:1901987;cellular process#GO:0009987;cell cycle phase transition#GO:0044770;regulation of cell cycle process#GO:0010564;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of macromolecule metabolic process#GO:0060255;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;regulation of phosphorylation#GO:0042325;regulation of mitotic cell cycle#GO:0007346;regulation of transferase activity#GO:0051338;regulation of cell cycle G1/S phase transition#GO:1902806;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 microtubule organizing center#GO:0005815;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;serine/threonine protein kinase complex#GO:1902554;protein kinase complex#GO:1902911;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856 kinase activator#PC00138 Wnt signaling pathway#P00057>Wnt Target Genes#G01558;Cell cycle#P00013>Cyclin D#P00484 CIOIN|Ensembl=ENSCING00000000406.3|UniProtKB=F6SEF7 F6SEF7 PTHR24229:SF109 NEUROPEPTIDES RECEPTOR SOMATOSTATIN RECEPTOR TYPE 2-LIKE neuropeptide binding#GO:0042923;signaling receptor activity#GO:0038023;binding#GO:0005488;peptide binding#GO:0042277;amide binding#GO:0033218;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;neuropeptide signaling pathway#GO:0007218;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;neuron projection#GO:0043005;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 CIOIN|Ensembl=ENSCING00000024789.1|UniProtKB=A0A1W2W6L9 A0A1W2W6L9 LOC100179082 PTHR24073:SF528 DRAB5-RELATED INTRAFLAGELLAR TRANSPORT PROTEIN 22 HOMOLOG GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824 localization#GO:0051179;organic substance transport#GO:0071702;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;transport#GO:0006810;protein transport#GO:0015031;nitrogen compound transport#GO:0071705;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104 cellular anatomical entity#GO:0110165;endomembrane system#GO:0012505 small GTPase#PC00208;G-protein#PC00020 CIOIN|Ensembl=ENSCING00000009103.4|UniProtKB=F6Q9C5 F6Q9C5 PTHR44111:SF1 ELONGATOR COMPLEX PROTEIN 2 ELONGATOR COMPLEX PROTEIN 2 CIOIN|Ensembl=ENSCING00000024340.1|UniProtKB=H2XJG8 H2XJG8 PTHR45749:SF37 FAMILY NOT NAMED OS05G0311600 PROTEIN CIOIN|Ensembl=ENSCING00000023852.1|UniProtKB=H2XKG0 H2XKG0 PTHR20772:SF2 PROTEIN FMP42 PROTEIN FMP42 CIOIN|Ensembl=ENSCING00000025009.1|UniProtKB=H2XP82 H2XP82 LOC100185873 PTHR22980:SF0 CORTISTATIN CENTROMERE PROTEIN S protein-containing complex binding#GO:0044877;binding#GO:0005488;chromatin binding#GO:0003682 cellular aromatic compound metabolic process#GO:0006725;nuclear division#GO:0000280;cell cycle process#GO:0022402;nucleobase-containing compound metabolic process#GO:0006139;reciprocal homologous recombination#GO:0140527;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;meiotic cell cycle process#GO:1903046;DNA-templated DNA replication#GO:0006261;meiosis I cell cycle process#GO:0061982;reproductive process#GO:0022414;reciprocal meiotic recombination#GO:0007131;replication fork processing#GO:0031297;meiosis I#GO:0007127;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;meiotic cell cycle#GO:0051321;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;DNA recombination#GO:0006310;resolution of meiotic recombination intermediates#GO:0000712;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;reproduction#GO:0000003;meiotic nuclear division#GO:0140013;organelle organization#GO:0006996;sexual reproduction#GO:0019953;cell cycle#GO:0007049;organelle fission#GO:0048285;homologous recombination#GO:0035825;DNA replication#GO:0006260;DNA metabolic process#GO:0006259 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 neuropeptide#PC00162;peptide hormone#PC00179 CIOIN|Ensembl=ENSCING00000019580.1|UniProtKB=H2XNB0 H2XNB0 PTHR10807:SF109 MYOTUBULARIN-RELATED SET DOMAIN BINDING FACTOR, ISOFORM A nucleoside-triphosphatase regulator activity#GO:0060589;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;GTPase regulator activity#GO:0030695;catalytic activity#GO:0003824;molecular function regulator activity#GO:0098772;hydrolase activity#GO:0016787;enzyme regulator activity#GO:0030234;phosphoric ester hydrolase activity#GO:0042578;guanyl-nucleotide exchange factor activity#GO:0005085 phospholipid dephosphorylation#GO:0046839;lipid metabolic process#GO:0006629;phosphatidylinositol dephosphorylation#GO:0046856;cellular metabolic process#GO:0044237;phosphatidylinositol metabolic process#GO:0046488;glycerophospholipid metabolic process#GO:0006650;lipid modification#GO:0030258;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;dephosphorylation#GO:0016311;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;membrane#GO:0016020;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;phosphatase#PC00181 CIOIN|Ensembl=ENSCING00000008529.3|UniProtKB=F7A0G1 F7A0G1 LOC100177777 PTHR10336:SF196 PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C FAMILY PROTEIN PHOSPHOINOSITIDE PHOSPHOLIPASE C hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;phospholipase C activity#GO:0004629;phospholipase activity#GO:0004620;phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578 lipid metabolic process#GO:0006629;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;regulation of sequestering of calcium ion#GO:0051282;regulation of signaling#GO:0023051;regulation of localization#GO:0032879;inorganic ion transmembrane transport#GO:0098660;phospholipid metabolic process#GO:0006644;phosphorus metabolic process#GO:0006793;calcium ion transport#GO:0006816;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;glycerolipid metabolic process#GO:0046486;establishment of localization#GO:0051234;monoatomic cation transport#GO:0006812;intracellular signal transduction#GO:0035556;cell-cell signaling#GO:0007267;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;calcium ion transmembrane transport#GO:0070588;cellular metabolic process#GO:0044237;release of sequestered calcium ion into cytosol#GO:0051209;cell communication#GO:0007154;glycerophospholipid metabolic process#GO:0006650;phosphatidylinositol metabolic process#GO:0046488;cellular process#GO:0009987;primary metabolic process#GO:0044238;localization#GO:0051179;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;monoatomic ion transmembrane transport#GO:0034220;calcium ion transmembrane import into cytosol#GO:0097553;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;organophosphate metabolic process#GO:0019637;monoatomic ion transport#GO:0006811;cellular lipid metabolic process#GO:0044255;negative regulation of sequestering of calcium ion#GO:0051283;monoatomic cation transmembrane transport#GO:0098655 phospholipase#PC00186 Oxytocin receptor mediated signaling pathway#P04391>PLC beta#P04530;5HT2 type receptor mediated signaling pathway#P04374>PLC#P04412;Thyrotropin-releasing hormone receptor signaling pathway#P04394>PLC#P04581 CIOIN|Ensembl=ENSCING00000012734.2|UniProtKB=F7A9N7 F7A9N7 PTHR46574:SF1 43 KDA RECEPTOR-ASSOCIATED PROTEIN OF THE SYNAPSE 43 KDA RECEPTOR-ASSOCIATED PROTEIN OF THE SYNAPSE protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 regulation of cell communication#GO:0010646;regulation of signaling#GO:0023051;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;synaptic signaling#GO:0099536;regulation of trans-synaptic signaling#GO:0099177;positive regulation of synaptic transmission#GO:0050806;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;signaling#GO:0023052;cell-cell signaling#GO:0007267 cell junction#GO:0030054;synapse#GO:0045202;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;neuromuscular junction#GO:0031594;plasma membrane#GO:0005886 CIOIN|Ensembl=ENSCING00000016570.2|UniProtKB=A7BK23 A7BK23 Ci-GH18 PTHR11177:SF317 CHITINASE CHITINASE 12-RELATED glycosidase#PC00110;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000022216.1|UniProtKB=F6WVM4 F6WVM4 PTHR24412:SF497 KELCH PROTEIN KELCH-LIKE PROTEIN 18 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000024685.1|UniProtKB=H2XKL9 H2XKL9 PTHR16260:SF3 SIMILAR TO 1700123O20RIK PROTEIN CHROMOSOME 14 OPEN READING FRAME 119-LIKE-RELATED CIOIN|Ensembl=ENSCING00000002708.3|UniProtKB=F6UE24 F6UE24 LOC100184300 PTHR12638:SF0 PROTEIN MAGO NASHI HOMOLOG MAGO HOMOLOG, EXON JUNCTION COMPLEX SUBUNIT-RELATED cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000019493.1|UniProtKB=H2XZ45 H2XZ45 LOC100187492 PTHR15654:SF2 COILED-COIL DOMAIN-CONTAINING PROTEIN 113-RELATED COILED-COIL DOMAIN-CONTAINING PROTEIN 113 organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cell projection organization#GO:0030030;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031 axoneme#GO:0005930;microtubule organizing center#GO:0005815;cytoplasmic region#GO:0099568;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;ciliary basal body#GO:0036064;ciliary plasm#GO:0097014;plasma membrane bounded cell projection cytoplasm#GO:0032838;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;cell projection#GO:0042995;cilium#GO:0005929 CIOIN|Ensembl=ENSCING00000001991.3|UniProtKB=F6XFM9 F6XFM9 LOC100184191 PTHR22950:SF702 AMINO ACID TRANSPORTER AMINO ACID TRANSPORTER PROTEIN L-amino acid transmembrane transporter activity#GO:0015179;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;amino acid transmembrane transporter activity#GO:0015171;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215;organic acid transmembrane transporter activity#GO:0005342 localization#GO:0051179;organic substance transport#GO:0071702;amino acid transmembrane transport#GO:0003333;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;amino acid transport#GO:0006865;organic anion transport#GO:0015711;organic acid transport#GO:0015849;transport#GO:0006810;nitrogen compound transport#GO:0071705;organic acid transmembrane transport#GO:1903825;carboxylic acid transport#GO:0046942;cellular process#GO:0009987;carboxylic acid transmembrane transport#GO:1905039 cellular anatomical entity#GO:0110165;membrane#GO:0016020 amino acid transporter#PC00046;transporter#PC00227 CIOIN|Ensembl=ENSCING00000003981.3|UniProtKB=A0A1W2VZT1 A0A1W2VZT1 LOC100175749 PTHR11143:SF7 60S RIBOSOMAL PROTEIN L26 FAMILY MEMBER RIBOSOMAL PROTEIN L26 LIKE 1 structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;structural molecule activity#GO:0005198;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cytoplasmic translation#GO:0002181;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;ribosomal large subunit biogenesis#GO:0042273;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;cellular component organization or biogenesis#GO:0071840;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic large ribosomal subunit#GO:0022625;large ribosomal subunit#GO:0015934;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000007901.3|UniProtKB=Q4H2S1 Q4H2S1 Ci-SoxC PTHR45803:SF10 SOX100B HMG BOX DOMAIN-CONTAINING PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;epithelium development#GO:0060429;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;regulation of biosynthetic process#GO:0009889;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;negative regulation of biosynthetic process#GO:0009890;regulation of DNA-templated transcription#GO:0006355;negative regulation of metabolic process#GO:0009892;tissue development#GO:0009888;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;tissue morphogenesis#GO:0048729;morphogenesis of an epithelium#GO:0002009;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;HMG box transcription factor#PC00024 CIOIN|Ensembl=ENSCING00000002910.3|UniProtKB=F6SC38 F6SC38 PTHR15526:SF5 MUSKELIN MUSKELIN cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000010133.3|UniProtKB=F6PIA8 F6PIA8 LOC100175149 PTHR20884:SF8 GDP-D-GLUCOSE PHOSPHORYLASE 1 GDP-D-GLUCOSE PHOSPHORYLASE 1 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779 monosaccharide metabolic process#GO:0005996;hexose metabolic process#GO:0019318;glucose metabolic process#GO:0006006;carbohydrate metabolic process#GO:0005975;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000000935.3|UniProtKB=F6TDG4 F6TDG4 PTHR31281:SF3 PROTEIN FAM219A PROTEIN FAM219A CIOIN|Ensembl=ENSCING00000024126.1|UniProtKB=H2XM57 H2XM57 PTHR43758:SF2 7,8-DIHYDRO-8-OXOGUANINE TRIPHOSPHATASE OXIDIZED PURINE NUCLEOSIDE TRIPHOSPHATE HYDROLASE hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 phosphatase#PC00181;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000012461.2|UniProtKB=F6UU30 F6UU30 PTHR12461:SF42 HYPOXIA-INDUCIBLE FACTOR 1 ALPHA INHIBITOR-RELATED JMJC DOMAIN-CONTAINING PROTEIN protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000003555.3|UniProtKB=H2XZZ6 H2XZZ6 PTHR48012:SF10 STERILE20-LIKE KINASE, ISOFORM B-RELATED FI20177P1 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;phosphorylation#GO:0016310;protein phosphorylation#GO:0006468;cellular process#GO:0009987;protein metabolic process#GO:0019538;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000009616.3|UniProtKB=F7ACY4 F7ACY4 PTHR13486:SF2 TELOMERE LENGTH AND SILENCING PROTEIN 1 TLS1 FAMILY MEMBER SPLICING FACTOR C9ORF78 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000012833.2|UniProtKB=F6W382 F6W382 LOC100183845 PTHR12424:SF8 TWEETY-RELATED PROTEIN TWEETY inorganic molecular entity transmembrane transporter activity#GO:0015318;chloride channel activity#GO:0005254;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;chloride transmembrane transporter activity#GO:0015108;monoatomic anion transmembrane transporter activity#GO:0008509;inorganic anion transmembrane transporter activity#GO:0015103;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267;monoatomic ion channel activity#GO:0005216 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 CIOIN|Ensembl=ENSCING00000007220.3|UniProtKB=F6U936 F6U936 PTHR46174:SF1 CXXC-TYPE ZINC FINGER PROTEIN 1 CXXC-TYPE ZINC FINGER PROTEIN 1 protein binding#GO:0005515;methylated histone binding#GO:0035064;histone binding#GO:0042393;binding#GO:0005488;modification-dependent protein binding#GO:0140030 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of RNA biosynthetic process#GO:2001141;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of RNA metabolic process#GO:0051254;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;histone methyltransferase complex#GO:0035097;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;methyltransferase complex#GO:0034708;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513;Set1C/COMPASS complex#GO:0048188 CIOIN|Ensembl=ENSCING00000002908.3|UniProtKB=H2Y3R2 H2Y3R2 PTHR11051:SF8 GLYCOSYL HYDROLASE-RELATED PROTEIN-GLUCOSYLGALACTOSYLHYDROXYLYSINE GLUCOSIDASE hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 carbohydrate metabolic process#GO:0005975;organic substance metabolic process#GO:0071704;primary metabolic process#GO:0044238;metabolic process#GO:0008152 glycosidase#PC00110;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000009072.3|UniProtKB=F6QIP6 F6QIP6 lhx3 PTHR24208:SF128 LIM/HOMEOBOX PROTEIN LHX LIM3, ISOFORM G sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;neurogenesis#GO:0022008;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;multicellular organism development#GO:0007275;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;system development#GO:0048731;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;neuron differentiation#GO:0030182;multicellular organismal process#GO:0032501;regulation of macromolecule biosynthetic process#GO:0010556;generation of neurons#GO:0048699;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 CIOIN|Ensembl=ENSCING00000007200.3|UniProtKB=F6YRI1 F6YRI1 PTHR11384:SF67 ATP-BINDING CASSETTE, SUB-FAMILY D MEMBER ATP-BINDING CASSETTE SUB-FAMILY D MEMBER 1 carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;ATPase-coupled transmembrane transporter activity#GO:0042626;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;lipid transporter activity#GO:0005319;transmembrane transporter activity#GO:0022857;primary active transmembrane transporter activity#GO:0015399;ATP-dependent activity#GO:0140657;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167;ATP binding#GO:0005524 lipid metabolic process#GO:0006629;monocarboxylic acid transport#GO:0015718;cellular localization#GO:0051641;macromolecule localization#GO:0033036;organic acid transport#GO:0015849;fatty acid transport#GO:0015908;transport#GO:0006810;lipid catabolic process#GO:0016042;lipid modification#GO:0030258;lipid transport#GO:0006869;carboxylic acid transmembrane transport#GO:1905039;organic substance transport#GO:0071702;establishment of localization#GO:0051234;fatty acid beta-oxidation#GO:0006635;catabolic process#GO:0009056;lipid localization#GO:0010876;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;cellular lipid catabolic process#GO:0044242;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;intracellular lipid transport#GO:0032365;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;transmembrane transport#GO:0055085;organic anion transport#GO:0015711;cellular metabolic process#GO:0044237;carboxylic acid transport#GO:0046942;lipid oxidation#GO:0034440;cellular component organization#GO:0016043;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;fatty acid catabolic process#GO:0009062;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic acid catabolic process#GO:0016054;fatty acid metabolic process#GO:0006631;small molecule catabolic process#GO:0044282;organelle organization#GO:0006996;establishment of localization in cell#GO:0051649;organic acid transmembrane transport#GO:1903825;intracellular transport#GO:0046907;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;peroxisome organization#GO:0007031;long-chain fatty acid transport#GO:0015909;monocarboxylic acid catabolic process#GO:0072329;small molecule metabolic process#GO:0044281 bounding membrane of organelle#GO:0098588;peroxisomal membrane#GO:0005778;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;peroxisome#GO:0005777;microbody#GO:0042579;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ATP-binding cassette (ABC) transporter#PC00003;transporter#PC00227 CIOIN|Ensembl=ENSCING00000007611.3|UniProtKB=F6X5U2 F6X5U2 PTHR43782:SF3 ARGINASE ARGINASE cation binding#GO:0043169;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;transition metal ion binding#GO:0046914;hydrolase activity#GO:0016787;metal ion binding#GO:0046872;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;ion binding#GO:0043167 oxoacid metabolic process#GO:0043436;proteinogenic amino acid metabolic process#GO:0170039;arginine metabolic process#GO:0006525;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;amino acid catabolic process#GO:0009063;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;nitrogen compound metabolic process#GO:0006807;alpha-amino acid metabolic process#GO:1901605;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;carboxylic acid metabolic process#GO:0019752;L-amino acid metabolic process#GO:0170033;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000023759.1|UniProtKB=H2Y1G7 H2Y1G7 PTHR14002:SF20 ENDOGLIN/TGF-BETA RECEPTOR TYPE III ZONA PELLUCIDA-LIKE DOMAIN-CONTAINING PROTEIN 1 transmembrane signal receptor#PC00197 CIOIN|Ensembl=ENSCING00000008401.3|UniProtKB=F6XRP8 F6XRP8 PTHR43826:SF3 GLUCOSE-6-PHOSPHATE EXCHANGER SLC37A4 GLUCOSE-6-PHOSPHATE EXCHANGER SLC37A4 inorganic molecular entity transmembrane transporter activity#GO:0015318;carbohydrate derivative transmembrane transporter activity#GO:1901505;secondary active transmembrane transporter activity#GO:0015291;antiporter activity#GO:0015297;transmembrane transporter activity#GO:0022857;inorganic anion transmembrane transporter activity#GO:0015103;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215 localization#GO:0051179;inorganic anion transmembrane transport#GO:0098661;organic substance transport#GO:0071702;phosphate ion transport#GO:0006817;organophosphate ester transport#GO:0015748;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;carbohydrate derivative transport#GO:1901264;inorganic anion transport#GO:0015698 primary active transporter#PC00068;transporter#PC00227 CIOIN|Ensembl=ENSCING00000013399.2|UniProtKB=F6VRL4 F6VRL4 LOC100186777 PTHR24173:SF74 ANKYRIN REPEAT CONTAINING ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 16 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000024902.1|UniProtKB=H2XPJ2 H2XPJ2 LOC100176966 PTHR44554:SF1 LRP2-BINDING PROTEIN LRP2-BINDING PROTEIN CIOIN|Ensembl=ENSCING00000003521.3|UniProtKB=F7AZ47 F7AZ47 n PTHR24033:SF151 EGF-LIKE DOMAIN-CONTAINING PROTEIN NOTCH 2 CIOIN|Ensembl=ENSCING00000016440.2|UniProtKB=F7BC57 F7BC57 PTHR24412:SF498 KELCH PROTEIN KELCH-LIKE PROTEIN 26 ISOFORM X1 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000008870.3|UniProtKB=F6QYE3 F6QYE3 PTHR13140:SF679 MYOSIN UNCONVENTIONAL MYOSIN IC microfilament motor activity#GO:0000146;cytoskeletal protein binding#GO:0008092;ATP-dependent activity#GO:0140657;binding#GO:0005488;actin filament binding#GO:0051015;cytoskeletal motor activity#GO:0003774;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779 actin filament-based movement#GO:0030048;transport#GO:0006810;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;establishment of localization#GO:0051234;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;import into cell#GO:0098657 microvillus#GO:0005902;actin-based cell projection#GO:0098858;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cytoskeleton#GO:0005856;cell projection#GO:0042995;plasma membrane#GO:0005886 actin binding motor protein#PC00040 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 CIOIN|Ensembl=ENSCING00000003831.3|UniProtKB=F6ZSP8 F6ZSP8 PTHR24064:SF650 SOLUTE CARRIER FAMILY 22 MEMBER MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000012809.2|UniProtKB=F6WPS3 F6WPS3 LOC100176210 PTHR14083:SF0 YIP1 INTERACTING FACTOR HOMOLOG YIF1 PROTEIN YIP1D-INTERACTING FACTOR 1, ISOFORM C localization#GO:0051179;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;establishment of localization#GO:0051234;transport#GO:0006810;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987 bounding membrane of organelle#GO:0098588;COPII-coated ER to Golgi transport vesicle#GO:0030134;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;coated vesicle#GO:0030135;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;Golgi membrane#GO:0000139;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 CIOIN|Ensembl=ENSCING00000009130.4|UniProtKB=F6S399 F6S399 LOC100185430 PTHR43097:SF4 GLUTAMINE-TRNA LIGASE GLUTAMINE--TRNA LIGASE catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;ligase activity#GO:0016874;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;peptide biosynthetic process#GO:0043043;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 aminoacyl-tRNA synthetase#PC00047;translational protein#PC00263 Heme biosynthesis#P02746>Glutamyl-tRNA-synthetase#P02977 CIOIN|Ensembl=ENSCING00000007248.3|UniProtKB=F6UWQ4 F6UWQ4 PTHR19143:SF459 FIBRINOGEN/TENASCIN/ANGIOPOEITIN FIBRINOGEN C-TERMINAL DOMAIN-CONTAINING PROTEIN external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 CIOIN|Ensembl=ENSCING00000019390.1|UniProtKB=H2Y1V8 H2Y1V8 PTHR46811:SF1 COILED-COIL-HELIX-COILED-COIL-HELIX DOMAIN-CONTAINING PROTEIN 7 COILED-COIL-HELIX-COILED-COIL-HELIX DOMAIN-CONTAINING PROTEIN 7 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;mitochondrial respiratory chain complex assembly#GO:0033108;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;mitochondrion organization#GO:0007005;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000008872.2|UniProtKB=F6QY42 F6QY42 LOC100183392 PTHR12049:SF7 PROTEIN ARGININE METHYLTRANSFERASE NDUFAF7, MITOCHONDRIAL PROTEIN ARGININE METHYLTRANSFERASE NDUFAF7, MITOCHONDRIAL N-methyltransferase activity#GO:0008170;transferase activity#GO:0016740;catalytic activity#GO:0003824;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a protein#GO:0140096;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;protein methyltransferase activity#GO:0008276 CIOIN|Ensembl=ENSCING00000004199.3|UniProtKB=F7B4V3 F7B4V3 PTHR11960:SF8 EUKARYOTIC TRANSLATION INITIATION FACTOR 4E RELATED EUKARYOTIC TRANSLATION INITIATION FACTOR 4E1-RELATED nucleic acid binding#GO:0003676;RNA binding#GO:0003723;translation regulator activity#GO:0045182;binding#GO:0005488;organic cyclic compound binding#GO:0097159;translation initiation factor activity#GO:0003743;RNA cap binding#GO:0000339;translation regulator activity, nucleic acid binding#GO:0090079;translation factor activity, RNA binding#GO:0008135 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;translational initiation#GO:0006413;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;intracellular protein-containing complex#GO:0140535;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622 translation initiation factor#PC00224;translation factor#PC00223;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000019847.1|UniProtKB=H2XK01 H2XK01 ci-zf(phd)-21 PTHR46309:SF1 PHD FINGER PROTEIN 12 PHD FINGER PROTEIN 12 regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 CIOIN|Ensembl=ENSCING00000009214.3|UniProtKB=Q4H3S2 Q4H3S2 Ci-CBFB PTHR10276:SF3 CORE-BINDING FACTOR, BETA SUBUNIT CORE-BINDING FACTOR SUBUNIT BETA sequence-specific DNA binding#GO:0043565;molecular adaptor activity#GO:0060090;nucleic acid binding#GO:0003676;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;binding#GO:0005488;organic cyclic compound binding#GO:0097159;protein-macromolecule adaptor activity#GO:0030674;DNA binding#GO:0003677;transcription coactivator activity#GO:0003713 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218 CIOIN|Ensembl=ENSCING00000004450.3|UniProtKB=F6U3Q1 F6U3Q1 LOC100184510 PTHR14145:SF1 26S PROTESOME SUBUNIT 6 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 6 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489 CIOIN|Ensembl=ENSCING00000021089.1|UniProtKB=H2XQD9 H2XQD9 PTHR11571:SF222 GLUTATHIONE S-TRANSFERASE GLUTATHIONE TRANSFERASE glutathione transferase activity#GO:0004364;transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824 sulfur compound metabolic process#GO:0006790;nitrogen compound metabolic process#GO:0006807;peptide metabolic process#GO:0006518;cellular modified amino acid metabolic process#GO:0006575;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular process#GO:0009987;glutathione metabolic process#GO:0006749;amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000004418.3|UniProtKB=A0A1W2WII7 A0A1W2WII7 LOC100181559 PTHR44156:SF28 SUPERNUMERARY LIMBS, ISOFORM B-RELATED WD REPEAT-CONTAINING PROTEIN 38 ubiquitin ligase-substrate adaptor activity#GO:1990756;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein polyubiquitination#GO:0000209;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 SCF ubiquitin ligase complex#GO:0019005;intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;cullin-RING ubiquitin ligase complex#GO:0031461;transferase complex#GO:1990234 CIOIN|Ensembl=ENSCING00000005843.3|UniProtKB=F6V766 F6V766 zf(c3h)-12 PTHR14089:SF6 PRE-MRNA-SPLICING FACTOR RBM22 PRE-MRNA-SPLICING FACTOR RBM22 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;snRNA binding#GO:0017069;pre-mRNA binding#GO:0036002;binding#GO:0005488;organic cyclic compound binding#GO:0097159 ribonucleoprotein complex#GO:1990904;catalytic step 2 spliceosome#GO:0071013;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;U2-type spliceosomal complex#GO:0005684;cellular anatomical entity#GO:0110165;organelle#GO:0043226;Prp19 complex#GO:0000974;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622 RNA splicing factor#PC00148;RNA processing factor#PC00147;RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000004088.3|UniProtKB=F6YI25 F6YI25 LOC100183289 PTHR46098:SF1 TRNA (CYTOSINE(38)-C(5))-METHYLTRANSFERASE TRNA (CYTOSINE(38)-C(5))-METHYLTRANSFERASE RNA processing factor#PC00147 CIOIN|Ensembl=ENSCING00000004485.3|UniProtKB=F6TFE5 F6TFE5 PTHR10590:SF4 SODIUM/NUCLEOSIDE COTRANSPORTER SOLUTE CARRIER FAMILY 28 MEMBER 3 carbohydrate derivative transmembrane transporter activity#GO:1901505;secondary active transmembrane transporter activity#GO:0015291;nucleoside transmembrane transporter activity#GO:0005337;transmembrane transporter activity#GO:0022857;symporter activity#GO:0015293;nucleobase-containing compound transmembrane transporter activity#GO:0015932;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215 localization#GO:0051179;organic substance transport#GO:0071702;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;nucleobase-containing compound transport#GO:0015931;transport#GO:0006810;nitrogen compound transport#GO:0071705;cellular process#GO:0009987;carbohydrate derivative transport#GO:1901264 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transporter#PC00227 CIOIN|Ensembl=ENSCING00000005468.3|UniProtKB=F6U696 F6U696 LOC100185787 PTHR10791:SF30 RAG1-ACTIVATING PROTEIN 1 SUGAR TRANSPORTER SWEET1 transmembrane transporter activity#GO:0022857;sugar transmembrane transporter activity#GO:0051119;transporter activity#GO:0005215;carbohydrate transmembrane transporter activity#GO:0015144 localization#GO:0051179;organic substance transport#GO:0071702;establishment of localization#GO:0051234;carbohydrate transport#GO:0008643;transport#GO:0006810 cellular anatomical entity#GO:0110165;membrane#GO:0016020 CIOIN|Ensembl=ENSCING00000006501.3|UniProtKB=F6PW28 F6PW28 PTHR11932:SF169 CULLIN CULLIN 1 enzyme binding#GO:0019899;molecular adaptor activity#GO:0060090;protein binding#GO:0005515;ubiquitin protein ligase binding#GO:0031625;binding#GO:0005488;ubiquitin-like protein ligase binding#GO:0044389;protein-macromolecule adaptor activity#GO:0030674 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 SCF ubiquitin ligase complex#GO:0019005;intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;cullin-RING ubiquitin ligase complex#GO:0031461;catalytic complex#GO:1902494;transferase complex#GO:1990234 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 Parkinson disease#P00049>Cul-1#P01239 CIOIN|Ensembl=ENSCING00000018472.1|UniProtKB=H2XKJ4 H2XKJ4 PTHR34400:SF4 FAMILY NOT NAMED MEMBRANE PROTEIN CIOIN|Ensembl=ENSCING00000021494.1|UniProtKB=H2XVY7 H2XVY7 PTHR11353:SF84 CHAPERONIN T-COMPLEX PROTEIN 1 SUBUNIT ALPHA protein binding#GO:0005515;unfolded protein binding#GO:0051082;binding#GO:0005488 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein folding#GO:0006457;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;chaperonin-containing T-complex#GO:0005832;protein folding chaperone complex#GO:0101031;intracellular anatomical structure#GO:0005622 chaperonin#PC00073 CIOIN|Ensembl=ENSCING00000000099.3|UniProtKB=F6T5Q7 F6T5Q7 PTHR15031:SF4 CARTILAGE INTERMEDIATE LAYER PROTEIN CLIP CARTILAGE INTERMEDIATE LAYER PROTEIN 1 CIOIN|Ensembl=ENSCING00000014406.2|UniProtKB=F6ZWX3 F6ZWX3 ap4 PTHR15741:SF27 BASIC HELIX-LOOP-HELIX ZIP TRANSCRIPTION FACTOR TRANSCRIPTION FACTOR AP-4 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 DNA-binding transcription factor#PC00218 CIOIN|Ensembl=ENSCING00000018374.1|UniProtKB=H2XYT6 H2XYT6 PTHR12124:SF47 POLYMYOSITIS/SCLERODERMA AUTOANTIGEN-RELATED EXOSOME COMPONENT 10 CIOIN|Ensembl=ENSCING00000003819.3|UniProtKB=F6Z8X9 F6Z8X9 PTHR24056:SF171 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE 20 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;phosphorylation#GO:0016310;protein phosphorylation#GO:0006468;cellular process#GO:0009987;protein metabolic process#GO:0019538;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 CIOIN|Ensembl=ENSCING00000002096.3|UniProtKB=A0A1W2WKJ7 A0A1W2WKJ7 LOC100184961 PTHR43969:SF9 GLUTATHIONE S TRANSFERASE D10, ISOFORM A-RELATED GLUTATHIONE S TRANSFERASE D10, ISOFORM A-RELATED glutathione transferase activity#GO:0004364;transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824 sulfur compound metabolic process#GO:0006790;nitrogen compound metabolic process#GO:0006807;peptide metabolic process#GO:0006518;cellular modified amino acid metabolic process#GO:0006575;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular process#GO:0009987;glutathione metabolic process#GO:0006749;amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000005517.3|UniProtKB=F6YPB8 F6YPB8 PTHR23023:SF226 DIMETHYLANILINE MONOOXYGENASE FLAVIN-CONTAINING MONOOXYGENASE oxygenase#PC00177;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000006287.3|UniProtKB=F6YMX2 F6YMX2 LOC100177967 PTHR22870:SF335 REGULATOR OF CHROMOSOME CONDENSATION RCC1 AND BTB DOMAIN CONTAINING PROTEIN 2 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 CIOIN|Ensembl=ENSCING00000007774.3|UniProtKB=F6XT34 F6XT34 PTHR46232:SF1 SMARCE1 REGULATOR OF CHROMATIN SWI_SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY E MEMBER 1 nucleosome binding#GO:0031491;nucleic acid binding#GO:0003676;chromatin DNA binding#GO:0031490;nuclear receptor binding#GO:0016922;binding#GO:0005488;organic cyclic compound binding#GO:0097159;chromatin binding#GO:0003682;DNA binding#GO:0003677;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;transcription factor binding#GO:0008134;DNA-binding transcription factor binding#GO:0140297 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of biosynthetic process#GO:0009890;negative regulation of RNA metabolic process#GO:0051253;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of metabolic process#GO:0009892;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;catalytic complex#GO:1902494;ATPase complex#GO:1904949;SWI/SNF superfamily-type complex#GO:0070603;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;SWI/SNF complex#GO:0016514;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 chromatin/chromatin-binding, or -regulatory protein#PC00077 Wnt signaling pathway#P00057>SWI/SNF#P01435 CIOIN|Ensembl=ENSCING00000005276.3|UniProtKB=F6UIV5 F6UIV5 PTHR19328:SF75 HEDGEHOG-INTERACTING PROTEIN ALDOSE SUGAR DEHYDROGENASE YLII protein-binding activity modulator#PC00095 CIOIN|Ensembl=ENSCING00000023821.1|UniProtKB=H2XLX4 H2XLX4 PTHR11178:SF1 IRON-SULFUR CLUSTER SCAFFOLD PROTEIN NFU-RELATED NFU1 IRON-SULFUR CLUSTER SCAFFOLD HOMOLOG, MITOCHONDRIAL CIOIN|Ensembl=ENSCING00000023034.1|UniProtKB=H2XWG8 H2XWG8 PTHR23311:SF5 HEAT SHOCK REGULATED 2 CENTROSOMAL PROTEIN OF 72 KDA CIOIN|Ensembl=ENSCING00000020293.1|UniProtKB=H2XWM1 H2XWM1 PTHR11214:SF283 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE N-ACETYLLACTOSAMINIDE BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE 4-LIKE transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;protein O-linked glycosylation#GO:0006493;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 bounding membrane of organelle#GO:0098588;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;Golgi membrane#GO:0000139;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111 CIOIN|Ensembl=ENSCING00000019849.1|UniProtKB=F6YGY7 F6YGY7 PTHR46734:SF1 TELOMERIC REPEAT-BINDING FACTOR 1 TERF1 TELOMERIC REPEAT-BINDING FACTOR 1 CIOIN|Ensembl=ENSCING00000018903.1|UniProtKB=H2XX49 H2XX49 LOC100187405 PTHR46461:SF1 KELCH DOMAIN-CONTAINING PROTEIN 3 KELCH DOMAIN-CONTAINING PROTEIN 3 protein-containing complex binding#GO:0044877;binding#GO:0005488;chromatin binding#GO:0003682 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000023332.1|UniProtKB=H2XMA1 H2XMA1 PTHR23050:SF325 CALCIUM BINDING PROTEIN CENTRIN-3 calmodulin-related#PC00061 CIOIN|Ensembl=ENSCING00000012428.1|UniProtKB=F6VIE9 F6VIE9 PTHR12480:SF41 ARGININE DEMETHYLASE AND LYSYL-HYDROXYLASE JMJD JMJC DOMAIN-CONTAINING PROTEIN sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;dioxygenase activity#GO:0051213;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity#GO:0016491 positive regulation of gene expression#GO:0010628;positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of protein metabolic process#GO:0051246;regulation of amide metabolic process#GO:0034248;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;protein modification process#GO:0036211;regulation of cellular component organization#GO:0051128;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;protein hydroxylation#GO:0018126;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;positive regulation of biological process#GO:0048518;positive regulation of translation#GO:0045727;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;regulation of protein-containing complex disassembly#GO:0043244;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;positive regulation of protein metabolic process#GO:0051247;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;post-transcriptional regulation of gene expression#GO:0010608;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;regulation of translation#GO:0006417;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000005356.3|UniProtKB=F7BFD3 F7BFD3 meis PTHR11850:SF266 HOMEOBOX PROTEIN TRANSCRIPTION FACTORS HOMEOBOX PROTEIN HOMOTHORAX DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nitrogen compound metabolic process#GO:0051171;animal organ development#GO:0048513;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of cell population proliferation#GO:0008284;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;system development#GO:0048731;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;anatomical structure morphogenesis#GO:0009653;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;visual system development#GO:0150063;sensory system development#GO:0048880;pattern specification process#GO:0007389;positive regulation of biological process#GO:0048518;regulation of cell population proliferation#GO:0042127;regulation of DNA-templated transcription#GO:0006355;multicellular organism development#GO:0007275;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA metabolic process#GO:0051252;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;embryo development#GO:0009790;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;eye development#GO:0001654;biological regulation#GO:0065007;animal organ morphogenesis#GO:0009887;multicellular organismal process#GO:0032501;positive regulation of RNA metabolic process#GO:0051254;sensory organ development#GO:0007423;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 CIOIN|Ensembl=ENSCING00000005146.3|UniProtKB=F6VAF3 F6VAF3 LOC100183762 PTHR34649:SF1 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 99 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 99 structural protein#PC00211 CIOIN|Ensembl=ENSCING00000002741.3|UniProtKB=F6T2T0 F6T2T0 PTHR11929:SF145 ALPHA- 1,3 -FUCOSYLTRANSFERASE ALPHA-(1,3)-FUCOSYLTRANSFERASE FUT-1 transferase activity#GO:0016740;fucosyltransferase activity#GO:0008417;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 glycosylation#GO:0070085;metabolic process#GO:0008152 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000024544.1|UniProtKB=H2XLX0 H2XLX0 PTHR14107:SF16 WD REPEAT PROTEIN AT02583P CIOIN|Ensembl=ENSCING00000018953.1|UniProtKB=H2XXC4 H2XXC4 PTHR46965:SF1 BTB/POZ DOMAIN-CONTAINING PROTEIN 19 BTB_POZ DOMAIN-CONTAINING PROTEIN 19 CIOIN|Ensembl=ENSCING00000021117.1|UniProtKB=H2XPL7 H2XPL7 LOC100176706 PTHR21964:SF34 BREAST CANCER METASTASIS-SUPPRESSOR 1 SIN3 HISTONE DEACETYLASE COREPRESSOR COMPLEX COMPONENT SDS3 enzyme binding#GO:0019899;histone deacetylase binding#GO:0042826;protein binding#GO:0005515;binding#GO:0005488 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of biosynthetic process#GO:0009890;negative regulation of RNA metabolic process#GO:0051253;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;Sin3-type complex#GO:0070822;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;histone deacetylase complex#GO:0000118;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 CIOIN|Ensembl=ENSCING00000000249.3|UniProtKB=F6SGP1 F6SGP1 PTHR16200:SF8 RING ZINC FINGER E3 UBIQUITIN-PROTEIN LIGASE ZNRF3-LIKE transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000016816.2|UniProtKB=F6RZE8 F6RZE8 PTHR23236:SF2 EUKARYOTIC TRANSLATION INITIATION FACTOR 4B/4H EUKARYOTIC TRANSLATION INITIATION FACTOR 4B translation initiation factor#PC00224;translation factor#PC00223 CIOIN|Ensembl=ENSCING00000003899.3|UniProtKB=F6TA16 F6TA16 LOC100179389 PTHR43899:SF40 RH59310P INACTIVE HYDROXYSTEROID DEHYDROGENASE-LIKE PROTEIN 1 oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000007649.3|UniProtKB=F6VWY9 F6VWY9 LOC100181352 PTHR10036:SF3 CD59 GLYCOPROTEIN PROTEIN SLEEPLESS-RELATED CIOIN|Ensembl=ENSCING00000017106.2|UniProtKB=F6WG12 F6WG12 PTHR13812:SF19 KETIMINE REDUCTASE MU-CRYSTALLIN KETIMINE REDUCTASE MU-CRYSTALLIN reductase#PC00198;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000002720.3|UniProtKB=F6UCU4 F6UCU4 PTHR42687:SF1 L-THREONINE 3-DEHYDROGENASE L-THREONINE 3-DEHYDROGENASE, MITOCHONDRIAL oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 oxoacid metabolic process#GO:0043436;proteinogenic amino acid metabolic process#GO:0170039;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;amino acid catabolic process#GO:0009063;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;nitrogen compound metabolic process#GO:0006807;alpha-amino acid metabolic process#GO:1901605;catabolic process#GO:0009056;aspartate family amino acid metabolic process#GO:0009066;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;L-amino acid metabolic process#GO:0170033;carboxylic acid metabolic process#GO:0019752;amino acid metabolic process#GO:0006520;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000020048.1|UniProtKB=H2XT21 H2XT21 PTHR24134:SF2 ANKYRIN REPEAT-CONTAINING PROTEIN DDB_G0279043 SUBFAMILY NOT NAMED CIOIN|Ensembl=ENSCING00000001277.3|UniProtKB=F6ZCL3 F6ZCL3 PTHR12170:SF2 MACROPHAGE ERYTHROBLAST ATTACHER-RELATED E3 UBIQUITIN-PROTEIN TRANSFERASE MAEA transferase activity#GO:0016740;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000007786.3|UniProtKB=F6X4F9 F6X4F9 PTHR14063:SF1 PROTEIN LIN-7 HOMOLOG PDZ DOMAIN-CONTAINING PROTEIN 11 establishment or maintenance of cell polarity#GO:0007163;cellular localization#GO:0051641;establishment or maintenance of epithelial cell apical/basal polarity#GO:0045197;macromolecule localization#GO:0033036;transport#GO:0006810;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;secretion#GO:0046903;neurotransmitter transport#GO:0006836;synaptic signaling#GO:0099536;signal release#GO:0023061;establishment or maintenance of apical/basal cell polarity#GO:0035088;cell-cell signaling#GO:0007267;signaling#GO:0023052;secretion by cell#GO:0032940;neurotransmitter secretion#GO:0007269;localization within membrane#GO:0051668;protein localization to membrane#GO:0072657;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;protein localization#GO:0008104;protein localization to cell periphery#GO:1990778;localization#GO:0051179;cellular macromolecule localization#GO:0070727;signal release from synapse#GO:0099643;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;establishment or maintenance of bipolar cell polarity#GO:0061245;export from cell#GO:0140352 basal plasma membrane#GO:0009925;synapse#GO:0045202;anchoring junction#GO:0070161;cell-cell junction#GO:0005911;basolateral plasma membrane#GO:0016323;cell junction#GO:0030054;plasma membrane region#GO:0098590;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;basal part of cell#GO:0045178;membrane#GO:0016020;plasma membrane#GO:0005886 cell junction protein#PC00070 CIOIN|Ensembl=ENSCING00000018363.1|UniProtKB=H2XY11 H2XY11 LOC100178437 PTHR43651:SF3 1,4-ALPHA-GLUCAN-BRANCHING ENZYME 1,4-ALPHA-GLUCAN-BRANCHING ENZYME transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 carbohydrate metabolic process#GO:0005975;organic substance metabolic process#GO:0071704;primary metabolic process#GO:0044238;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 amylase#PC00048;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000023462.1|UniProtKB=H2XLY4 H2XLY4 LOC100177378 PTHR10036:SF25 CD59 GLYCOPROTEIN HEP21 PROTEIN CIOIN|Ensembl=ENSCING00000018518.1|UniProtKB=H2XVR8 H2XVR8 PTHR24256:SF545 TRYPTASE-RELATED INACTIVE SERINE PROTEASE 54 hydrolase activity#GO:0016787;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 serine protease#PC00203;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000004310.3|UniProtKB=F6SI05 F6SI05 PTHR11451:SF46 THREONINE-TRNA LIGASE THREONINE--TRNA LIGASE catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;ligase activity#GO:0016874;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;peptide biosynthetic process#GO:0043043;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 aminoacyl-tRNA synthetase#PC00047;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000007787.3|UniProtKB=F6X4E3 F6X4E3 PTHR45749:SF14 FAMILY NOT NAMED TTF-TYPE DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000012169.2|UniProtKB=F6TV42 F6TV42 LOC100181810 PTHR31054:SF3 ZYGOTE ARREST PROTEIN 1-LIKE ISOFORM X1 ZYGOTE ARREST PROTEIN 1-LIKE macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;translation#GO:0006412;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000000682.2|UniProtKB=F6QS01 F6QS01 LOC100177131 PTHR34916:SF1 GI:13385330 GI:13385330 CIOIN|Ensembl=ENSCING00000012726.2|UniProtKB=F7ASV3 F7ASV3 LOC100180635 PTHR31078:SF1 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 300 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 300 structural protein#PC00211 CIOIN|Ensembl=ENSCING00000018766.1|UniProtKB=H2XVJ6 H2XVJ6 PTHR14002:SF43 ENDOGLIN/TGF-BETA RECEPTOR TYPE III DELTA-LIKE PROTEIN transmembrane signal receptor#PC00197 CIOIN|Ensembl=ENSCING00000018165.1|UniProtKB=H2Y1Y8 H2Y1Y8 PTHR11761:SF8 50S/60S RIBOSOMAL PROTEIN L14/L23 LARGE RIBOSOMAL SUBUNIT PROTEIN UL14 structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;structural molecule activity#GO:0005198;binding#GO:0005488;organic cyclic compound binding#GO:0097159;rRNA binding#GO:0019843 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic large ribosomal subunit#GO:0022625;large ribosomal subunit#GO:0015934;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;ribosomal subunit#GO:0044391 ribosomal protein#PC00202;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000000213.3|UniProtKB=F6VTB6 F6VTB6 LOC100185055 PTHR48148:SF3 KERATINOCYTE PROLINE-RICH PROTEIN KERATINOCYTE PROLINE-RICH PROTEIN CIOIN|Ensembl=ENSCING00000006347.3|UniProtKB=F6PRI9 F6PRI9 PTHR10924:SF6 MAJOR FACILITATOR SUPERFAMILY PROTEIN-RELATED SOLUTE CARRIER FAMILY 49 MEMBER A3 cellular anatomical entity#GO:0110165;membrane#GO:0016020 secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000013792.2|UniProtKB=F6RE33 F6RE33 PTHR23050:SF518 CALCIUM BINDING PROTEIN AT16150P-RELATED cation binding#GO:0043169;small molecule binding#GO:0036094;molecular function regulator activity#GO:0098772;binding#GO:0005488;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;enzyme regulator activity#GO:0030234 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 calmodulin-related#PC00061 B cell activation#P00010>Calmodulin#P00375;Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Calmodulin#P00755;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Phosphorylase b kinase#P00716;T cell activation#P00053>Calmodulin#P01305 CIOIN|Ensembl=ENSCING00000005382.3|UniProtKB=F7AWE3 F7AWE3 LOC100184268 PTHR12420:SF42 PHD FINGER PROTEIN G2_M PHASE-SPECIFIC E3 UBIQUITIN-PROTEIN LIGASE DNA metabolism protein#PC00009 CIOIN|Ensembl=ENSCING00000004100.3|UniProtKB=F6YH85 F6YH85 PTHR10201:SF331 MATRIX METALLOPROTEINASE MATRIX METALLOPROTEINASE-14-LIKE ISOFORM X1 hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular component organization or biogenesis#GO:0071840;extracellular structure organization#GO:0043062;external encapsulating structure organization#GO:0045229;catabolic process#GO:0009056;cellular component organization#GO:0016043;cellular process#GO:0009987;extracellular matrix organization#GO:0030198;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000007482.3|UniProtKB=F6XWZ8 F6XWZ8 LOC100180520 PTHR12689:SF4 A1 CISTRON SPLICING FACTOR AAR2-RELATED PROTEIN AAR2 HOMOLOG cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;RNA processing#GO:0006396;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;protein-RNA complex assembly#GO:0022618;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;spliceosomal snRNP assembly#GO:0000387;organic substance metabolic process#GO:0071704;mRNA splicing, via spliceosome#GO:0000398;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;protein-containing complex organization#GO:0043933;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;ribonucleoprotein complex biogenesis#GO:0022613;mRNA processing#GO:0006397;protein-RNA complex organization#GO:0071826;RNA splicing, via transesterification reactions#GO:0000375 RNA splicing factor#PC00148;RNA processing factor#PC00147;RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000004041.3|UniProtKB=H2Y3P6 H2Y3P6 PTHR11200:SF300 INOSITOL 5-PHOSPHATASE TYPE II INOSITOL 1,4,5-TRISPHOSPHATE 5-PHOSPHATASE hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 lipid metabolic process#GO:0006629;phospholipid dephosphorylation#GO:0046839;phosphatidylinositol dephosphorylation#GO:0046856;cellular metabolic process#GO:0044237;phosphatidylinositol metabolic process#GO:0046488;glycerophospholipid metabolic process#GO:0006650;lipid modification#GO:0030258;cellular process#GO:0009987;phospholipid metabolic process#GO:0006644;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;dephosphorylation#GO:0016311;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 metabolite interconversion enzyme#PC00262;phosphatase#PC00181 CIOIN|Ensembl=ENSCING00000004970.3|UniProtKB=F7BP70 F7BP70 PTHR11579:SF0 PROTEIN-L-ISOASPARTATE O-METHYLTRANSFERASE PROTEIN-L-ISOASPARTATE(D-ASPARTATE) O-METHYLTRANSFERASE transferase activity#GO:0016740;O-methyltransferase activity#GO:0008171;catalytic activity#GO:0003824;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a protein#GO:0140096;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;protein methyltransferase activity#GO:0008276 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 methyltransferase#PC00155 CIOIN|Ensembl=ENSCING00000013511.2|UniProtKB=A0A1W3JGZ9 A0A1W3JGZ9 LOC100183853 PTHR12589:SF7 PYRUVOYL TETRAHYDROBIOPTERIN SYNTHASE 6-PYRUVOYL TETRAHYDROBIOPTERIN SYNTHASE CIOIN|Ensembl=ENSCING00000006666.3|UniProtKB=F6XAG2 F6XAG2 PTHR24246:SF27 OLFACTORY RECEPTOR AND ADENOSINE RECEPTOR ADENOSINE RECEPTOR, ISOFORM A G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711 CIOIN|Ensembl=ENSCING00000020650.1|UniProtKB=H2XQ41 H2XQ41 PTHR12159:SF9 G/T AND G/U MISMATCH-SPECIFIC DNA GLYCOSYLASE G_T MISMATCH-SPECIFIC THYMINE DNA GLYCOSYLASE catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;catalytic activity, acting on DNA#GO:0140097;DNA N-glycosylase activity#GO:0019104;catalytic activity#GO:0003824 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;base-excision repair#GO:0006284;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;DNA damage response#GO:0006974;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 DNA glycosylase#PC00010 CIOIN|Ensembl=ENSCING00000003740.3|UniProtKB=F6U6H9 F6U6H9 PTHR43591:SF101 METHYLTRANSFERASE METHYLTRANSFERASE-LIKE PROTEIN 27 methyltransferase#PC00155;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000018370.1|UniProtKB=H2Y2P4 H2Y2P4 PTHR31912:SF34 IP13529P NOTOCHORD-RELATED PROTEIN CIOIN|Ensembl=ENSCING00000009332.3|UniProtKB=F6Z491 F6Z491 PTHR11599:SF14 PROTEASOME SUBUNIT ALPHA/BETA PROTEASOME SUBUNIT ALPHA TYPE-5 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 peptidase complex#GO:1905368;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;proteasome complex#GO:0000502;endopeptidase complex#GO:1905369;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protease#PC00190;protein modifying enzyme#PC00260 Parkinson disease#P00049>20S proteasome#P01227 CIOIN|Ensembl=ENSCING00000005649.3|UniProtKB=A0A1W3JEL3 A0A1W3JEL3 LOC100177716 PTHR24412:SF495 KELCH PROTEIN KELCH-LIKE PROTEIN 24 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000020739.1|UniProtKB=H2XPX0 H2XPX0 PTHR22891:SF111 EUKARYOTIC TRANSLATION INITIATION FACTOR 2C PROTEIN ARGONAUTE-3 catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;nuclease activity#GO:0004518;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;catalytic activity, acting on a nucleic acid#GO:0140640;endonuclease activity#GO:0004519;RNA nuclease activity#GO:0004540;RNA endonuclease activity#GO:0004521 negative regulation of gene expression#GO:0010629;regulatory ncRNA-mediated gene silencing#GO:0031047;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of biosynthetic process#GO:0009890;negative regulation of metabolic process#GO:0009892;regulation of biological process#GO:0050789;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;P granule#GO:0043186;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464;intracellular anatomical structure#GO:0005622 translation initiation factor#PC00224;translation factor#PC00223 CIOIN|Ensembl=ENSCING00000006014.3|UniProtKB=F6SG74 F6SG74 PTHR24411:SF55 NUCLEAR FACTOR ERYTHROID 2-RELATED FACTOR SEGMENTATION PROTEIN CAP'N'COLLAR sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;basic leucine zipper transcription factor#PC00056 CIOIN|Ensembl=ENSCING00000022616.1|UniProtKB=H2XX88 H2XX88 LOC100183796 PTHR22588:SF3 VWFA DOMAIN-CONTAINING PROTEIN VWFA DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000023106.1|UniProtKB=H2Y0A1 H2Y0A1 LOC100178222 PTHR46374:SF1 PROTEIN CBG07384 START DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000004879.3|UniProtKB=F7B9A9 F7B9A9 PTHR12166:SF8 CALCIUM-DEPENDENT SECRETION ACTIVATOR CALCIUM-DEPENDENT SECRETION ACTIVATOR localization#GO:0051179;establishment of localization#GO:0051234;exocytosis#GO:0006887;secretion#GO:0046903;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;export from cell#GO:0140352;secretion by cell#GO:0032940 membrane trafficking regulatory protein#PC00151 CIOIN|Ensembl=ENSCING00000006038.3|UniProtKB=F7BLS5 F7BLS5 PTHR10758:SF2 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 3/COP9 SIGNALOSOME COMPLEX SUBUNIT 3 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 3 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 peptidase complex#GO:1905368;protein-containing complex#GO:0032991;proteasome accessory complex#GO:0022624;proteasome regulatory particle#GO:0005838;catalytic complex#GO:1902494;proteasome regulatory particle, lid subcomplex#GO:0008541;proteasome complex#GO:0000502;endopeptidase complex#GO:1905369;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 protease#PC00190;protein modifying enzyme#PC00260 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489;Cell cycle#P00013>Proteasome#P00480 CIOIN|Ensembl=ENSCING00000007395.3|UniProtKB=F6UL80 F6UL80 PTHR24340:SF73 HOMEOBOX PROTEIN NKX HOMEOBOX PROTEIN BAGPIPE-RELATED sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 CIOIN|Ensembl=ENSCING00000001878.3|UniProtKB=F6SJF7 F6SJF7 PTHR10036:SF3 CD59 GLYCOPROTEIN PROTEIN SLEEPLESS-RELATED CIOIN|Ensembl=ENSCING00000008650.3|UniProtKB=F6ZYG1 F6ZYG1 LOC100180882 PTHR21477:SF13 ZGC:172139 KIAA0930 CIOIN|Ensembl=ENSCING00000023342.1|UniProtKB=H2XRX5 H2XRX5 LOC100182817 PTHR12141:SF5 ARFAPTIN-RELATED ARFAPTIN lipid binding#GO:0008289;phospholipid binding#GO:0005543;binding#GO:0005488 cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;trans-Golgi network membrane#GO:0032588;organelle subcompartment#GO:0031984;Golgi apparatus subcompartment#GO:0098791;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;membrane#GO:0016020;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 vesicle coat protein#PC00235 CIOIN|Ensembl=ENSCING00000006522.3|UniProtKB=F6PH07 F6PH07 LOC100176009 PTHR24353:SF153 CYCLIC NUCLEOTIDE-DEPENDENT PROTEIN KINASE CAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT 1 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;serine/threonine protein kinase complex#GO:1902554;cytosol#GO:0005829;protein kinase complex#GO:1902911;intracellular protein-containing complex#GO:0140535;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Metabotropic glutamate receptor group III pathway#P00039>PKA#P01035;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>PKA#P01075;5HT1 type receptor mediated signaling pathway#P04373>PKA#P04403;Enkephalin release#P05913>PKA#P05972;Histamine H2 receptor mediated signaling pathway#P04386>PKA#P04491;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PKA#P00862;Dopamine receptor mediated signaling pathway#P05912>PKA#P05946;Beta2 adrenergic receptor signaling pathway#P04378>PKA#P04444;Metabotropic glutamate receptor group II pathway#P00040>PKA#P01050;Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>PKA#P00746;Beta1 adrenergic receptor signaling pathway#P04377>PKA#P04437;Endothelin signaling pathway#P00019>PKA#P00570;Metabotropic glutamate receptor group I pathway#P00041>PKA#P01059 CIOIN|Ensembl=ENSCING00000009478.3|UniProtKB=F7AEX3 F7AEX3 PTHR22298:SF29 ENDO-1,4-BETA-GLUCANASE ENDOGLUCANASE CIOIN|Ensembl=ENSCING00000012198.2|UniProtKB=F7B9N2 F7B9N2 PTHR14165:SF3 MAJOR VAULT PROTEIN MAJOR VAULT PROTEIN cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000003331.3|UniProtKB=F6SNC6 F6SNC6 PTHR23420:SF0 ADENOSYLHOMOCYSTEINASE ADENOSYLHOMOCYSTEINASE hydrolase activity#GO:0016787;catalytic activity#GO:0003824 cellular metabolic process#GO:0044237;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000000553.3|UniProtKB=F6Q7A1 F6Q7A1 LOC100178481 PTHR10131:SF153 TNF RECEPTOR ASSOCIATED FACTOR RING-TYPE DOMAIN-CONTAINING PROTEIN protein binding#GO:0005515;binding#GO:0005488;tumor necrosis factor receptor binding#GO:0005164;signaling receptor binding#GO:0005102;tumor necrosis factor receptor superfamily binding#GO:0032813;cytokine receptor binding#GO:0005126 regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;regulation of canonical NF-kappaB signal transduction#GO:0043122;regulation of signaling#GO:0023051;biological regulation#GO:0065007;regulation of intracellular signal transduction#GO:1902531 receptor complex#GO:0043235;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;plasma membrane signaling receptor complex#GO:0098802;plasma membrane protein complex#GO:0098797;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;cytoplasmic side of plasma membrane#GO:0009898;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000002383.2|UniProtKB=F6R4H7 F6R4H7 PTHR14052:SF0 ORIGIN RECOGNITION COMPLEX SUBUNIT 2 ORIGIN RECOGNITION COMPLEX SUBUNIT 2 sequence-specific double-stranded DNA binding#GO:1990837;DNA replication origin binding#GO:0003688;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690 origin recognition complex#GO:0000808;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;nuclear origin of replication recognition complex#GO:0005664;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 DNA metabolism protein#PC00009;replication origin binding protein#PC00199 CIOIN|Ensembl=ENSCING00000020190.1|UniProtKB=H2XQT2 H2XQT2 PTHR12137:SF54 CARBOHYDRATE SULFOTRANSFERASE CARBOHYDRATE SULFOTRANSFERASE sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824 transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000004246.2|UniProtKB=F6YG81 F6YG81 PTHR14043:SF2 CCAAT DISPLACEMENT PROTEIN-RELATED HOMEOBOX PROTEIN CUT homeodomain transcription factor#PC00119 CIOIN|Ensembl=ENSCING00000022613.1|UniProtKB=H2XK85 H2XK85 LOC100177460 PTHR45619:SF10 SERINE/THREONINE-PROTEIN PHOSPHATASE PP2A-RELATED SERINE_THREONINE-PROTEIN PHOSPHATASE 6 CATALYTIC SUBUNIT hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;protein serine/threonine phosphatase activity#GO:0004722;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 protein phosphatase#PC00195;protein modifying enzyme#PC00260 EGF receptor signaling pathway#P00018>PP2A#P00547;FGF signaling pathway#P00021>PP2A#P00629 CIOIN|Ensembl=ENSCING00000020163.1|UniProtKB=F7BDS3 F7BDS3 PTHR12286:SF5 SACCHAROPINE DEHYDROGENASE-LIKE OXIDOREDUCTASE SACCHAROPINE DEHYDROGENASE-LIKE OXIDOREDUCTASE lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;glycolipid metabolic process#GO:0006664;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;liposaccharide metabolic process#GO:1903509;membrane lipid biosynthetic process#GO:0046467;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;membrane lipid metabolic process#GO:0006643;glycolipid biosynthetic process#GO:0009247;cellular lipid metabolic process#GO:0044255;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 CIOIN|Ensembl=ENSCING00000016000.2|UniProtKB=F6WGU2 F6WGU2 PTHR43836:SF2 CATECHOL O-METHYLTRANSFERASE 1-RELATED CATECHOL O-METHYLTRANSFERASE 1-RELATED methyltransferase activity#GO:0008168;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;O-methyltransferase activity#GO:0008171;catalytic activity#GO:0003824 methyltransferase#PC00155;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000001546.4|UniProtKB=F6YKR9 F6YKR9 LOC100177581 PTHR18934:SF85 ATP-DEPENDENT RNA HELICASE ATP-DEPENDENT RNA HELICASE DHX8 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;helicase activity#GO:0004386;ATP-dependent activity#GO:0140657;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;catalytic activity, acting on a nucleic acid#GO:0140640 cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;RNA processing#GO:0006396;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;mRNA metabolic process#GO:0016071;cellular component disassembly#GO:0022411;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;mRNA splicing, via spliceosome#GO:0000398;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;protein-containing complex disassembly#GO:0032984;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;protein-containing complex organization#GO:0043933;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;protein-RNA complex organization#GO:0071826;RNA splicing, via transesterification reactions#GO:0000375 ribonucleoprotein complex#GO:1990904;catalytic step 2 spliceosome#GO:0071013;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA helicase#PC00032 CIOIN|Ensembl=ENSCING00000008717.3|UniProtKB=F6WC86 F6WC86 LOC100177484 PTHR47456:SF6 PHD-TYPE DOMAIN-CONTAINING PROTEIN SI:DKEY-31C13.1 CIOIN|Ensembl=ENSCING00000006355.3|UniProtKB=F6PR08 F6PR08 PTHR31144:SF1 UPF0602 PROTEIN C4ORF47 UPF0602 PROTEIN C4ORF47 supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;cytoplasmic microtubule#GO:0005881;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000022211.1|UniProtKB=H2XQB1 H2XQB1 PTHR35020:SF2 N-ACETYLGLUCOSAMINE-INDUCED PROTEIN 1 N-ACETYLGLUCOSAMINE-INDUCED PROTEIN 1 amino sugar metabolic process#GO:0006040;carbohydrate derivative metabolic process#GO:1901135;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000013861.2|UniProtKB=F6QG58 F6QG58 PTHR10920:SF18 RIBOSOMAL RNA METHYLTRANSFERASE RRNA METHYLTRANSFERASE 2, MITOCHONDRIAL catalytic activity, acting on RNA#GO:0140098;transferase activity#GO:0016740;O-methyltransferase activity#GO:0008171;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on a rRNA#GO:0140102;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;rRNA methyltransferase activity#GO:0008649;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;RNA methyltransferase activity#GO:0008173 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;RNA modification#GO:0009451;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;methylation#GO:0032259;macromolecule methylation#GO:0043414;nitrogen compound metabolic process#GO:0006807;RNA methylation#GO:0001510;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 RNA methyltransferase#PC00033 CIOIN|Ensembl=ENSCING00000007214.3|UniProtKB=F6W785 F6W785 PTHR11203:SF11 CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR FAMILY MEMBER CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 3 hydrolase activity, acting on ester bonds#GO:0016788;nucleic acid binding#GO:0003676;nuclease activity#GO:0004518;5'-3' exonuclease activity#GO:0008409;binding#GO:0005488;catalytic activity#GO:0003824;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters#GO:0016796;endonuclease activity#GO:0004519;catalytic activity, acting on a nucleic acid#GO:0140640;exonuclease activity#GO:0004527;RNA endonuclease activity#GO:0004521;catalytic activity, acting on RNA#GO:0140098;RNA binding#GO:0003723;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;RNA nuclease activity#GO:0004540 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;RNA processing#GO:0006396;mRNA polyadenylation#GO:0006378;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;mRNA 3'-end processing#GO:0031124;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;mRNA processing#GO:0006397;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;mRNA cleavage factor complex#GO:0005849;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;mRNA cleavage and polyadenylation specificity factor complex#GO:0005847;intracellular anatomical structure#GO:0005622 RNA processing factor#PC00147;RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000021618.1|UniProtKB=H2XJZ4 H2XJZ4 PTHR24031:SF54 RNA HELICASE ATP-DEPENDENT RNA HELICASE DDX10-RELATED cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA helicase#PC00032 CIOIN|Ensembl=ENSCING00000023833.1|UniProtKB=H2XNC6 H2XNC6 PTHR21680:SF0 COILED-COIL DOMAIN-CONTAINING PROTEIN 124 COILED-COIL DOMAIN-CONTAINING PROTEIN 124 transcription coactivator activity#GO:0003713;molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;protein-macromolecule adaptor activity#GO:0030674 cellular aromatic compound metabolic process#GO:0006725;DNA-templated transcription#GO:0006351;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;RNA biosynthetic process#GO:0032774;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;aromatic compound biosynthetic process#GO:0019438;transcription by RNA polymerase II#GO:0006366;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000001964.3|UniProtKB=F6SID0 F6SID0 PTHR10317:SF0 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT E EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT E macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;translational initiation#GO:0006413;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;eukaryotic translation initiation factor 3 complex#GO:0005852;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 translation initiation factor#PC00224;translation factor#PC00223;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000009630.4|UniProtKB=F6ZUD0 F6ZUD0 LOC100186469 PTHR10971:SF5 MRNA EXPORT FACTOR AND BUB3 MITOTIC CHECKPOINT PROTEIN BUB3 protein binding#GO:0005515;ubiquitin-like protein binding#GO:0032182;binding#GO:0005488;ubiquitin binding#GO:0043130 negative regulation of sister chromatid segregation#GO:0033046;negative regulation of mitotic sister chromatid separation#GO:2000816;negative regulation of biological process#GO:0048519;regulation of mitotic nuclear division#GO:0007088;signal transduction#GO:0007165;negative regulation of mitotic metaphase/anaphase transition#GO:0045841;regulation of chromosome segregation#GO:0051983;mitotic cell cycle checkpoint signaling#GO:0007093;negative regulation of chromosome organization#GO:2001251;regulation of chromosome separation#GO:1905818;negative regulation of mitotic nuclear division#GO:0045839;cell cycle process#GO:0022402;regulation of cellular component organization#GO:0051128;negative regulation of cell cycle process#GO:0010948;negative regulation of nuclear division#GO:0051784;negative regulation of mitotic sister chromatid segregation#GO:0033048;mitotic cell cycle process#GO:1903047;regulation of biological process#GO:0050789;cell cycle checkpoint signaling#GO:0000075;negative regulation of mitotic cell cycle phase transition#GO:1901991;mitotic cell cycle#GO:0000278;negative regulation of organelle organization#GO:0010639;regulation of mitotic sister chromatid segregation#GO:0033047;intracellular signal transduction#GO:0035556;negative regulation of cellular component organization#GO:0051129;negative regulation of cellular process#GO:0048523;signaling#GO:0023052;regulation of chromosome organization#GO:0033044;cellular response to stimulus#GO:0051716;regulation of mitotic sister chromatid separation#GO:0010965;regulation of nuclear division#GO:0051783;regulation of mitotic cell cycle phase transition#GO:1901990;negative regulation of cell cycle#GO:0045786;regulation of organelle organization#GO:0033043;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;mitotic spindle assembly checkpoint signaling#GO:0007094;negative regulation of chromosome segregation#GO:0051985;regulation of cell cycle phase transition#GO:1901987;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of mitotic cell cycle#GO:0045930;cell communication#GO:0007154;cellular process#GO:0009987;regulation of mitotic metaphase/anaphase transition#GO:0030071;regulation of cell cycle process#GO:0010564;response to stimulus#GO:0050896;negative regulation of chromosome separation#GO:1905819;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;regulation of sister chromatid segregation#GO:0033045;regulation of mitotic cell cycle#GO:0007346;negative regulation of metaphase/anaphase transition of cell cycle#GO:1902100 membrane-enclosed lumen#GO:0031974;supramolecular complex#GO:0099080;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;kinetochore#GO:0000776;nucleoplasm#GO:0005654;condensed chromosome, centromeric region#GO:0000779;condensed chromosome#GO:0000793;intracellular organelle lumen#GO:0070013;chromosome, centromeric region#GO:0000775;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;chromosomal region#GO:0098687;nuclear lumen#GO:0031981 RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000010471.3|UniProtKB=L7N0U1 L7N0U1 LOC100181270 PTHR11571:SF230 GLUTATHIONE S-TRANSFERASE GLUTATHIONE TRANSFERASE glutathione transferase activity#GO:0004364;transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824 sulfur compound metabolic process#GO:0006790;nitrogen compound metabolic process#GO:0006807;peptide metabolic process#GO:0006518;cellular modified amino acid metabolic process#GO:0006575;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular process#GO:0009987;glutathione metabolic process#GO:0006749;amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000004551.3|UniProtKB=F6ZQH5 F6ZQH5 PTHR12993:SF11 N-ACETYLGLUCOSAMINYL-PHOSPHATIDYLINOSITOL DE-N-ACETYLASE-RELATED N-ACETYLGLUCOSAMINYL-PHOSPHATIDYLINOSITOL DE-N-ACETYLASE hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824 deacetylase#PC00087;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000025138.1|UniProtKB=H2XS37 H2XS37 PTHR12984:SF3 SCY1-RELATED S/T PROTEIN KINASE-LIKE N-TERMINAL KINASE-LIKE PROTEIN non-receptor serine/threonine protein kinase#PC00167 CIOIN|Ensembl=ENSCING00000020777.1|UniProtKB=H2XLZ9 H2XLZ9 PTHR19134:SF555 RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE DELTA-LIKE ISOFORM X1 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;protein tyrosine phosphatase activity#GO:0004725;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 protein phosphatase#PC00195;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000002466.3|UniProtKB=F7AKQ3 F7AKQ3 PTHR42780:SF1 SOLEUCYL-TRNA SYNTHETASE ISOLEUCINE--TRNA LIGASE, CYTOPLASMIC catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;ligase activity#GO:0016874;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;peptide biosynthetic process#GO:0043043;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 aminoacyl-tRNA synthetase#PC00047;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000004933.3|UniProtKB=F7APZ8 F7APZ8 LOC100183713 PTHR10176:SF3 GLYCOGEN SYNTHASE GLYCOGEN [STARCH] SYNTHASE UDP-glucosyltransferase activity#GO:0035251;transferase activity#GO:0016740;glucosyltransferase activity#GO:0046527;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194;hexosyltransferase activity#GO:0016758 glucan metabolic process#GO:0044042;carbohydrate biosynthetic process#GO:0016051;macromolecule biosynthetic process#GO:0009059;polysaccharide biosynthetic process#GO:0000271;macromolecule metabolic process#GO:0043170;glycogen metabolic process#GO:0005977;generation of precursor metabolites and energy#GO:0006091;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;glycogen biosynthetic process#GO:0005978;energy derivation by oxidation of organic compounds#GO:0015980;primary metabolic process#GO:0044238;polysaccharide metabolic process#GO:0005976;glucan biosynthetic process#GO:0009250;energy reserve metabolic process#GO:0006112;carbohydrate metabolic process#GO:0005975;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000007851.3|UniProtKB=F6W673 F6W673 PTHR11685:SF210 RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING E3 UBIQUITIN-PROTEIN LIGASE ARIH2 ubiquitin-like protein conjugating enzyme binding#GO:0044390;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;enzyme binding#GO:0019899;protein binding#GO:0005515;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;protein polyubiquitination#GO:0000209;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000020831.1|UniProtKB=H2XTJ4 H2XTJ4 PTHR22674:SF6 NTPASE, KAP FAMILY P-LOOP DOMAIN-CONTAINING 1 NTPASE KAP FAMILY P-LOOP DOMAIN-CONTAINING PROTEIN 1 CIOIN|Ensembl=ENSCING00000013650.2|UniProtKB=Q4H2W9 Q4H2W9 Ci-Prox-A PTHR12198:SF0 HOMEOBOX PROTEIN PROSPERO/PROX-1/CEH-26 HOMEOBOX PROTEIN PROSPERO sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 CIOIN|Ensembl=ENSCING00000003175.2|UniProtKB=F6QDF2 F6QDF2 LOC104265312 PTHR31965:SF1 TRANSMEMBRANE PROTEIN 42 TRANSMEMBRANE PROTEIN 42 CIOIN|Ensembl=ENSCING00000019425.1|UniProtKB=H2XVX4 H2XVX4 PTHR10281:SF106 MEMBRANE-ASSOCIATED PROGESTERONE RECEPTOR COMPONENT-RELATED IP06960P-RELATED cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transmembrane signal receptor#PC00197 CIOIN|Ensembl=ENSCING00000021053.1|UniProtKB=H2XKC9 H2XKC9 LOC100178599 PTHR11183:SF100 GLYCOGENIN SUBFAMILY MEMBER GLYCOGENIN, ISOFORM E transferase activity#GO:0016740;catalytic activity#GO:0003824;glycosyltransferase activity#GO:0016757 glycosyltransferase#PC00111 CIOIN|Ensembl=ENSCING00000007328.2|UniProtKB=F6YKF5 F6YKF5 myod PTHR11534:SF9 MYOGENIC FACTOR MYOGENIC-DETERMINATION PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of cell differentiation#GO:0045597;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of cell differentiation#GO:0045595;positive regulation of developmental process#GO:0051094;regulation of RNA metabolic process#GO:0051252;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 DNA-binding transcription factor#PC00218;basic helix-loop-helix transcription factor#PC00055 CIOIN|Ensembl=ENSCING00000006112.2|UniProtKB=F6WDV1 F6WDV1 PTHR11785:SF512 AMINO ACID TRANSPORTER SOBREMESA, ISOFORM B L-amino acid transmembrane transporter activity#GO:0015179;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;amino acid transmembrane transporter activity#GO:0015171;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215;organic acid transmembrane transporter activity#GO:0005342 localization#GO:0051179;organic substance transport#GO:0071702;amino acid transmembrane transport#GO:0003333;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;amino acid transport#GO:0006865;organic anion transport#GO:0015711;organic acid transport#GO:0015849;transport#GO:0006810;nitrogen compound transport#GO:0071705;organic acid transmembrane transport#GO:1903825;carboxylic acid transport#GO:0046942;cellular process#GO:0009987;carboxylic acid transmembrane transport#GO:1905039 transporter#PC00227 CIOIN|Ensembl=ENSCING00000004391.3|UniProtKB=F6YP51 F6YP51 PTHR43243:SF4 INNER MEMBRANE TRANSPORTER YGJI-RELATED CATIONIC AMINO ACID TRANSPORTER 4 transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;amino acid transmembrane transporter activity#GO:0015171;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215;organic acid transmembrane transporter activity#GO:0005342 localization#GO:0051179;organic substance transport#GO:0071702;establishment of localization#GO:0051234;amino acid transport#GO:0006865;organic anion transport#GO:0015711;organic acid transport#GO:0015849;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942 amino acid transporter#PC00046;transporter#PC00227 CIOIN|Ensembl=ENSCING00000006197.3|UniProtKB=F7B1C7 F7B1C7 PTHR18849:SF3 LEUCINE RICH REPEAT PROTEIN LEUCINE RICH REPEAT CONTAINING 23 CIOIN|Ensembl=ENSCING00000018305.1|UniProtKB=H2XVG8 H2XVG8 LOC100186871 PTHR14564:SF4 MICOS COMPLEX SUBUNIT MIC26 / MIC27 FAMILY MEMBER MICOS COMPLEX SUBUNIT cellular component organization or biogenesis#GO:0071840;membrane organization#GO:0061024;organelle organization#GO:0006996;cellular component organization#GO:0016043;mitochondrial membrane organization#GO:0007006;mitochondrion organization#GO:0007005;cellular process#GO:0009987;inner mitochondrial membrane organization#GO:0007007 envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial envelope#GO:0005740;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227;mitochondrial protein-containing complex#GO:0098798 CIOIN|Ensembl=ENSCING00000005392.3|UniProtKB=F7ACG4 F7ACG4 PTHR23331:SF1 CXYORF1 WASH COMPLEX SUBUNIT 1 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;tubulin binding#GO:0015631;alpha-tubulin binding#GO:0043014;binding#GO:0005488 endosomal transport#GO:0016197;localization within membrane#GO:0051668;cellular localization#GO:0051641;vesicle-mediated transport to the plasma membrane#GO:0098876;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;cytosolic transport#GO:0016482;retrograde transport, endosome to Golgi#GO:0042147;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;endocytic recycling#GO:0032456;actin filament-based process#GO:0030029;exocytosis#GO:0006887;Arp2/3 complex-mediated actin nucleation#GO:0034314;establishment of localization#GO:0051234;organelle organization#GO:0006996;secretion#GO:0046903;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;establishment of localization in cell#GO:0051649;cytoskeleton organization#GO:0007010;intracellular transport#GO:0046907;actin cytoskeleton organization#GO:0030036;export from cell#GO:0140352;secretion by cell#GO:0032940 cytoplasm#GO:0005737;endosome#GO:0005768;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular vesicle#GO:0097708;recycling endosome#GO:0055037;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150 CIOIN|Ensembl=ENSCING00000009486.3|UniProtKB=F6YSM6 F6YSM6 PTHR12260:SF6 DAMAGE-CONTROL PHOSPHATASE ARMT1 DAMAGE-CONTROL PHOSPHATASE ARMT1 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 response to stimulus#GO:0050896;DNA damage response#GO:0006974;cellular response to stimulus#GO:0051716;response to stress#GO:0006950;cellular process#GO:0009987;cellular response to stress#GO:0033554 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 phosphatase#PC00181;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000014035.2|UniProtKB=F6QUS4 F6QUS4 PTHR23064:SF32 TROPONIN CALTRACTIN ICL1F cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 CIOIN|Ensembl=ENSCING00000014426.2|UniProtKB=F6YUZ1 F6YUZ1 PTHR31518:SF3 ARGININE/SERINE-RICH PROTEIN PNISR ARGININE_SERINE-RICH PROTEIN PNISR CIOIN|Ensembl=ENSCING00000007978.3|UniProtKB=F6WR94 F6WR94 LOC100176592 PTHR45752:SF156 LEUCINE-RICH REPEAT-CONTAINING RAS SUPPRESSOR PROTEIN 1 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000011254.2|UniProtKB=F6VFD2 F6VFD2 LOC100181021 PTHR14063:SF2 PROTEIN LIN-7 HOMOLOG PROTEIN LIN-7 HOMOLOG establishment or maintenance of cell polarity#GO:0007163;cellular localization#GO:0051641;establishment or maintenance of epithelial cell apical/basal polarity#GO:0045197;macromolecule localization#GO:0033036;transport#GO:0006810;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;secretion#GO:0046903;neurotransmitter transport#GO:0006836;synaptic signaling#GO:0099536;signal release#GO:0023061;establishment or maintenance of apical/basal cell polarity#GO:0035088;cell-cell signaling#GO:0007267;signaling#GO:0023052;secretion by cell#GO:0032940;neurotransmitter secretion#GO:0007269;localization within membrane#GO:0051668;protein localization to membrane#GO:0072657;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;protein localization#GO:0008104;protein localization to cell periphery#GO:1990778;localization#GO:0051179;cellular macromolecule localization#GO:0070727;signal release from synapse#GO:0099643;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;establishment or maintenance of bipolar cell polarity#GO:0061245;export from cell#GO:0140352 basal plasma membrane#GO:0009925;synapse#GO:0045202;anchoring junction#GO:0070161;cell-cell junction#GO:0005911;basolateral plasma membrane#GO:0016323;cell junction#GO:0030054;plasma membrane region#GO:0098590;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;basal part of cell#GO:0045178;membrane#GO:0016020;plasma membrane#GO:0005886 cell junction protein#PC00070 CIOIN|Ensembl=ENSCING00000020274.1|UniProtKB=H2Y3P5 H2Y3P5 PTHR23282:SF116 APICAL ENDOSOMAL GLYCOPROTEIN PRECURSOR. MAM DOMAIN-CONTAINING PROTEIN 2 CIOIN|Ensembl=ENSCING00000024398.1|UniProtKB=F6V980 F6V980 PTHR24193:SF128 ANKYRIN REPEAT PROTEIN GA-BINDING PROTEIN SUBUNIT BETA-1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of RNA metabolic process#GO:0051254;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000008531.3|UniProtKB=F6YDB9 F6YDB9 PTHR19308:SF14 PHOSPHATIDYLCHOLINE TRANSFER PROTEIN START DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000014885.2|UniProtKB=F6YS37 F6YS37 PTHR45617:SF165 LEUCINE RICH REPEAT FAMILY PROTEIN COMMON DPR-INTERACTING PROTEIN-RELATED scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000007257.3|UniProtKB=F6UVC2 F6UVC2 PTHR12187:SF11 AGAP000124-PA PHOSPHATIDYLINOSITOL-3,4-BISPHOSPHATE 4-PHOSPHATASE hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 phosphatase#PC00181;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000021325.1|UniProtKB=H2Y0G6 H2Y0G6 PTHR24102:SF28 PHD FINGER PROTEIN PHD-TYPE DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000004612.3|UniProtKB=F6PYU7 F6PYU7 PTHR13697:SF4 PHOSPHOFRUCTOKINASE ATP-DEPENDENT 6-PHOSPHOFRUCTOKINASE carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;phosphotransferase activity, alcohol group as acceptor#GO:0016773;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;carbohydrate kinase activity#GO:0019200;carbohydrate binding#GO:0030246;kinase activity#GO:0016301;cation binding#GO:0043169;transferase activity#GO:0016740;organic cyclic compound binding#GO:0097159;identical protein binding#GO:0042802;nucleoside phosphate binding#GO:1901265;protein binding#GO:0005515;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167;ATP binding#GO:0005524;monosaccharide binding#GO:0048029 ribonucleoside triphosphate metabolic process#GO:0009199;nucleoside triphosphate metabolic process#GO:0009141;heterocycle catabolic process#GO:0046700;ribonucleotide catabolic process#GO:0009261;pyridine nucleotide metabolic process#GO:0019362;nucleobase-containing compound metabolic process#GO:0006139;ATP metabolic process#GO:0046034;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;purine ribonucleotide catabolic process#GO:0009154;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;pyridine-containing compound metabolic process#GO:0072524;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;oxoacid metabolic process#GO:0043436;nucleoside phosphate catabolic process#GO:1901292;carbohydrate derivative catabolic process#GO:1901136;purine ribonucleoside triphosphate metabolic process#GO:0009205;generation of precursor metabolites and energy#GO:0006091;cellular metabolic process#GO:0044237;nucleotide catabolic process#GO:0009166;cellular nitrogen compound metabolic process#GO:0034641;nicotinamide nucleotide metabolic process#GO:0046496;nucleoside diphosphate catabolic process#GO:0009134;organic acid metabolic process#GO:0006082;ribonucleotide metabolic process#GO:0009259;monocarboxylic acid metabolic process#GO:0032787;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;organophosphate catabolic process#GO:0046434;small molecule catabolic process#GO:0044282;glycolytic process#GO:0006096;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;nucleotide metabolic process#GO:0009117;small molecule metabolic process#GO:0044281;cellular aromatic compound metabolic process#GO:0006725;monosaccharide metabolic process#GO:0005996;carbohydrate derivative metabolic process#GO:1901135;organonitrogen compound catabolic process#GO:1901565;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;purine-containing compound catabolic process#GO:0072523;cellular nitrogen compound catabolic process#GO:0044270;purine nucleotide catabolic process#GO:0006195;organic cyclic compound metabolic process#GO:1901360;carbohydrate catabolic process#GO:0016052;nucleoside diphosphate metabolic process#GO:0009132;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carbohydrate metabolic process#GO:0005975;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;heterocycle metabolic process#GO:0046483;organonitrogen compound metabolic process#GO:1901564;cellular process#GO:0009987;glucose metabolic process#GO:0006006;aromatic compound catabolic process#GO:0019439;organic cyclic compound catabolic process#GO:1901361;purine nucleoside triphosphate metabolic process#GO:0009144;hexose metabolic process#GO:0019318;carboxylic acid metabolic process#GO:0019752;nucleobase-containing small molecule metabolic process#GO:0055086 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;transferase complex#GO:1990234;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695 carbohydrate kinase#PC00065 Glycolysis#P00024>Phosphofructokinase-1#P00672 CIOIN|Ensembl=ENSCING00000000233.3|UniProtKB=F6T3I7 F6T3I7 LOC100175361 PTHR11711:SF193 ADP RIBOSYLATION FACTOR-RELATED ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 3 carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167 cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 G-protein#PC00020 CIOIN|Ensembl=ENSCING00000002510.3|UniProtKB=F6XSE6 F6XSE6 PTHR24060:SF134 METABOTROPIC GLUTAMATE RECEPTOR METABOTROPIC GLUTAMATE RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;adenylate cyclase inhibiting G protein-coupled glutamate receptor activity#GO:0001640;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888;glutamate receptor activity#GO:0008066 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GqPCR#P00730 CIOIN|Ensembl=ENSCING00000019301.1|UniProtKB=A0A1W2WKH9 A0A1W2WKH9 LOC100183333 PTHR28314:SF1 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 29 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 29 molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;protein binding#GO:0005515;transcription factor binding#GO:0008134;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;mediator complex#GO:0016592;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031;general transcription factor#PC00259 CIOIN|Ensembl=ENSCING00000013304.2|UniProtKB=F6Y043 F6Y043 LOC100179215 PTHR12298:SF4 PCDC2 PROGRAMMED CELL DEATH PROTEIN 2 -RELATED PROGRAMMED CELL DEATH PROTEIN 2 CIOIN|Ensembl=ENSCING00000015061.2|UniProtKB=F6S7Z3 F6S7Z3 PTHR11471:SF13 TUMOR NECROSIS FACTOR FAMILY MEMBER TNF FAMILY PROFILE DOMAIN-CONTAINING PROTEIN intercellular signal molecule#PC00207 CIOIN|Ensembl=ENSCING00000000288.3|UniProtKB=F6ZZJ8 F6ZZJ8 LOC100180632 PTHR11099:SF0 VACUOLAR SORTING PROTEIN 35 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 35 endosomal transport#GO:0016197;cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;cytosolic transport#GO:0016482;establishment of protein localization#GO:0045184;retrograde transport, endosome to Golgi#GO:0042147;protein localization#GO:0008104;localization#GO:0051179;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 membrane protein complex#GO:0098796;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;late endosome#GO:0005770 membrane traffic protein#PC00150 CIOIN|Ensembl=ENSCING00000006565.3|UniProtKB=F6QVH1 F6QVH1 PTHR18934:SF83 ATP-DEPENDENT RNA HELICASE PRE-MRNA-SPLICING FACTOR ATP-DEPENDENT RNA HELICASE DHX16 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;helicase activity#GO:0004386;ATP-dependent activity#GO:0140657;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;catalytic activity, acting on a nucleic acid#GO:0140640 ribonucleoprotein complex#GO:1990904;catalytic step 2 spliceosome#GO:0071013;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622 RNA helicase#PC00032 CIOIN|Ensembl=ENSCING00000012471.2|UniProtKB=F7BIB7 F7BIB7 PTHR24347:SF393 SERINE/THREONINE-PROTEIN KINASE SPAGHETTI-SQUASH ACTIVATOR, ISOFORM C transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>MLCK#P00877;Cytoskeletal regulation by Rho GTPase#P00016>MLCK#P00514 CIOIN|Ensembl=ENSCING00000000716.3|UniProtKB=F6Q4Z2 F6Q4Z2 PTHR13021:SF8 PRE-MRNA-SPLICING FACTOR ISY1 PRE-MRNA-SPLICING FACTOR ISY1 HOMOLOG cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;RNA processing#GO:0006396;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;protein-RNA complex assembly#GO:0022618;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;mRNA splicing, via spliceosome#GO:0000398;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular biosynthetic process#GO:0044249;mRNA splice site recognition#GO:0006376;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;protein-containing complex organization#GO:0043933;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;ribonucleoprotein complex biogenesis#GO:0022613;mRNA processing#GO:0006397;protein-RNA complex organization#GO:0071826;RNA splicing, via transesterification reactions#GO:0000375;spliceosomal complex assembly#GO:0000245 ribonucleoprotein complex#GO:1990904;catalytic step 2 spliceosome#GO:0071013;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;post-mRNA release spliceosomal complex#GO:0071014;spliceosomal complex#GO:0005681;Prp19 complex#GO:0000974;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA splicing factor#PC00148;RNA processing factor#PC00147;RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000005048.3|UniProtKB=F7A5J2 F7A5J2 LOC100186181 PTHR10335:SF17 RRNA 2-O-METHYLTRANSFERASE FIBRILLARIN FIBRILLARIN N-methyltransferase activity#GO:0008170;histone modifying activity#GO:0140993;nucleic acid binding#GO:0003676;binding#GO:0005488;catalytic activity#GO:0003824;histone methyltransferase activity#GO:0042054;catalytic activity, acting on a nucleic acid#GO:0140640;methyltransferase activity#GO:0008168;protein methyltransferase activity#GO:0008276;catalytic activity, acting on RNA#GO:0140098;RNA binding#GO:0003723;transferase activity#GO:0016740;organic cyclic compound binding#GO:0097159;catalytic activity, acting on a rRNA#GO:0140102;transferase activity, transferring one-carbon groups#GO:0016741;rRNA methyltransferase activity#GO:0008649;catalytic activity, acting on a protein#GO:0140096;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;RNA methyltransferase activity#GO:0008173 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;RNA modification#GO:0009451;rRNA modification#GO:0000154;RNA processing#GO:0006396;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;ribosome biogenesis#GO:0042254;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA 3'-end processing#GO:0031123;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;rRNA methylation#GO:0031167;nucleic acid metabolic process#GO:0090304;methylation#GO:0032259;macromolecule methylation#GO:0043414;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;RNA methylation#GO:0001510 RNA processing factor#PC00147 CIOIN|Ensembl=ENSCING00000024863.1|UniProtKB=H2XN87 H2XN87 LOC100178268 PTHR15478:SF10 PLECKSTRIN HOMOLOGY-LIKE DOMAIN, PQ-RICH PROTEIN SUBFAMILY NOT NAMED CIOIN|Ensembl=ENSCING00000002801.3|UniProtKB=F6XMR8 F6XMR8 PTHR19134:SF527 RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 7 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;protein tyrosine phosphatase activity#GO:0004725;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 protein phosphatase#PC00195;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000002253.3|UniProtKB=F6W2W8 F6W2W8 PTHR11950:SF31 RUNT RELATED SEGMENTATION PROTEIN RUNT cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 Runt transcription factor#PC00254;immunoglobulin fold transcription factor#PC00251 CIOIN|Ensembl=ENSCING00000022688.1|UniProtKB=H2XUX5 H2XUX5 LOC100177199 PTHR13439:SF0 CT120 PROTEIN TOPOISOMERASE I DAMAGE AFFECTED PROTEIN 4 lipid homeostasis#GO:0055088;homeostatic process#GO:0042592;chemical homeostasis#GO:0048878 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000006912.3|UniProtKB=F6WAW7 F6WAW7 LOC100184859 PTHR11669:SF1 REPLICATION FACTOR C / DNA POLYMERASE III GAMMA-TAU SUBUNIT REPLICATION FACTOR C SUBUNIT 3 ATP-dependent activity, acting on DNA#GO:0008094;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on DNA#GO:0140097;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;response to stress#GO:0006950;nitrogen compound metabolic process#GO:0006807;DNA-templated DNA replication#GO:0006261;DNA replication#GO:0006260;cellular response to stress#GO:0033554;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;replication fork#GO:0005657 DNA-directed DNA polymerase#PC00018 DNA replication#P00017>RFC#P00529 CIOIN|Ensembl=ENSCING00000019893.1|UniProtKB=F6XSJ3 F6XSJ3 PTHR22906:SF52 PROPERDIN ADHESION G PROTEIN-COUPLED RECEPTOR B1 CIOIN|Ensembl=ENSCING00000013754.2|UniProtKB=F7AHS5 F7AHS5 PTHR14202:SF0 60 KDA RIBONUCLEOPROTEIN SSA/RO RNA-BINDING PROTEIN RO60 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000005182.3|UniProtKB=F6RXF3 F6RXF3 PTHR14663:SF2 METHYLTRANSFERASE NSUN7-RELATED METHYLTRANSFERASE NSUN7-RELATED CIOIN|Ensembl=ENSCING00000007630.3|UniProtKB=A0A1W2WI90 A0A1W2WI90 LOC100178867 PTHR10802:SF2 MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM40 MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM40 HOMOLOG 1-RELATED protein transmembrane transporter activity#GO:0008320;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 cellular localization#GO:0051641;transmembrane transport#GO:0055085;macromolecule localization#GO:0033036;transport#GO:0006810;protein transmembrane transport#GO:0071806;protein targeting#GO:0006605;nitrogen compound transport#GO:0071705;establishment of protein localization to organelle#GO:0072594;protein localization to mitochondrion#GO:0070585;cellular process#GO:0009987;protein transmembrane import into intracellular organelle#GO:0044743;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;mitochondrial transport#GO:0006839;organic substance transport#GO:0071702;protein import into mitochondrial matrix#GO:0030150;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein targeting to mitochondrion#GO:0006626;establishment of protein localization to mitochondrion#GO:0072655;protein transport#GO:0015031;protein localization to organelle#GO:0033365;mitochondrial transmembrane transport#GO:1990542 envelope#GO:0031975;bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;intracellular membrane-bounded organelle#GO:0043231;mitochondrial outer membrane#GO:0005741;mitochondrial outer membrane translocase complex#GO:0005742;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;organelle outer membrane#GO:0031968;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867;mitochondrial protein-containing complex#GO:0098798 primary active transporter#PC00068;transporter#PC00227 CIOIN|Ensembl=ENSCING00000022966.1|UniProtKB=H2XTV2 H2XTV2 LOC100179388 PTHR13738:SF1 TROPONIN I TROPONIN I non-motor actin binding protein#PC00165 CIOIN|Ensembl=ENSCING00000014118.1|UniProtKB=F6R589 F6R589 LOC100184693 PTHR11352:SF0 PROLIFERATING CELL NUCLEAR ANTIGEN PROLIFERATING CELL NUCLEAR ANTIGEN enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;DNA-templated DNA replication#GO:0006261;DNA replication#GO:0006260;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA strand elongation involved in DNA replication#GO:0006271 DNA polymerase processivity factor#PC00015 DNA replication#P00017>PCNA#P00534 CIOIN|Ensembl=ENSCING00000003233.3|UniProtKB=F6QR95 F6QR95 PTHR24416:SF539 TYROSINE-PROTEIN KINASE RECEPTOR RECEPTOR PROTEIN-TYROSINE KINASE signaling receptor activity#GO:0038023;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;molecular transducer activity#GO:0060089;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672;transmembrane signaling receptor activity#GO:0004888 signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;positive regulation of cellular metabolic process#GO:0031325;developmental process#GO:0032502;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;regulation of molecular function#GO:0065009;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;positive regulation of phosphorylation#GO:0042327;cellular response to stimulus#GO:0051716;positive regulation of catalytic activity#GO:0043085;multicellular organism development#GO:0007275;positive regulation of phosphorus metabolic process#GO:0010562;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphate metabolic process#GO:0045937;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;multicellular organismal process#GO:0032501;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 receptor complex#GO:0043235;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 CIOIN|Ensembl=ENSCING00000009594.3|UniProtKB=F7AX97 F7AX97 PTHR48012:SF18 STERILE20-LIKE KINASE, ISOFORM B-RELATED HAPPYHOUR, ISOFORM A transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;nitrogen compound metabolic process#GO:0006807;biological regulation#GO:0065007;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Apoptosis signaling pathway#P00006>GCKR#P00311;Apoptosis signaling pathway#P00006>GCK#P00268 CIOIN|Ensembl=ENSCING00000003996.3|UniProtKB=F6WJS0 F6WJS0 PTHR24317:SF7 PEROXISOMAL TRANS-2-ENOYL-COA REDUCTASE PEROXISOMAL TRANS-2-ENOYL-COA REDUCTASE reductase#PC00198;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000022715.1|UniProtKB=H2XUY9 H2XUY9 PTHR11889:SF31 HEDGEHOG PROTEIN HEDGEHOG intercellular signal molecule#PC00207 Hedgehog signaling pathway#P00025>Hedgehog#P00688 CIOIN|Ensembl=ENSCING00000012187.2|UniProtKB=F6TU78 F6TU78 PTHR11538:SF26 PHENYLALANYL-TRNA SYNTHETASE FERREDOXIN-FOLD ANTICODON-BINDING DOMAIN-CONTAINING PROTEIN 1 catalytic activity, acting on RNA#GO:0140098;N-methyltransferase activity#GO:0008170;ligase activity#GO:0016874;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on a rRNA#GO:0140102;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;rRNA methyltransferase activity#GO:0008649;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;RNA methyltransferase activity#GO:0008173 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;cellular component biogenesis#GO:0044085;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;peptide metabolic process#GO:0006518;RNA modification#GO:0009451;rRNA modification#GO:0000154;RNA processing#GO:0006396;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;translation#GO:0006412;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;ribosome biogenesis#GO:0042254;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;cellular component organization or biogenesis#GO:0071840;rRNA methylation#GO:0031167;nucleic acid metabolic process#GO:0090304;peptide biosynthetic process#GO:0043043;macromolecule methylation#GO:0043414;methylation#GO:0032259;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;rRNA base methylation#GO:0070475;RNA methylation#GO:0001510;amino acid metabolic process#GO:0006520 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 aminoacyl-tRNA synthetase#PC00047 CIOIN|Ensembl=ENSCING00000013453.2|UniProtKB=F6VZ12 F6VZ12 PTHR18949:SF3 CALDESMON CALDESMON cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165 CIOIN|Ensembl=ENSCING00000024372.1|UniProtKB=H2XP89 H2XP89 PTHR45746:SF6 LP21163P LP21163P nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 regulation of cell communication#GO:0010646;regulation of GTPase activity#GO:0043087;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;regulation of G protein-coupled receptor signaling pathway#GO:0008277;regulation of catalytic activity#GO:0050790;positive regulation of hydrolase activity#GO:0051345;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of hydrolase activity#GO:0051336 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>RGS#P00704;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>RGS#P00731 CIOIN|Ensembl=ENSCING00000007237.3|UniProtKB=F6VKA6 F6VKA6 PTHR22588:SF3 VWFA DOMAIN-CONTAINING PROTEIN VWFA DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000018025.1|UniProtKB=H2Y1K1 H2Y1K1 PTHR23310:SF62 ACYL-COA-BINDING PROTEIN, ACBP ACYL-COA BINDING PROTEIN 1, ISOFORM A carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;amide binding#GO:0033218;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;lipid binding#GO:0008289;anion binding#GO:0043168;ion binding#GO:0043167 lipid metabolic process#GO:0006629;oxoacid metabolic process#GO:0043436;fatty acid metabolic process#GO:0006631;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular lipid metabolic process#GO:0044255;organic acid metabolic process#GO:0006082;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 transfer/carrier protein#PC00219 CIOIN|Ensembl=ENSCING00000023330.1|UniProtKB=H2XML9 H2XML9 LOC100184706 PTHR13314:SF2 CALCIUM CHANNEL FLOWER HOMOLOG CALCIUM CHANNEL FLOWER HOMOLOG localization#GO:0051179;vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234;cellular process#GO:0009987;transport#GO:0006810 CIOIN|Ensembl=ENSCING00000015262.2|UniProtKB=F6Q678 F6Q678 LOC778714 PTHR46805:SF1 FORKHEAD BOX PROTEIN J1 FORKHEAD BOX PROTEIN J1 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 CIOIN|Ensembl=ENSCING00000025017.1|UniProtKB=H2XV39 H2XV39 LOC100176052 PTHR10104:SF1 STATHMIN STATHMIN, ISOFORM D cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 regulation of microtubule-based process#GO:0032886;neurogenesis#GO:0022008;cell projection organization#GO:0030030;microtubule depolymerization#GO:0007019;developmental process#GO:0032502;microtubule cytoskeleton organization#GO:0000226;regulation of cellular component organization#GO:0051128;nervous system development#GO:0007399;microtubule polymerization or depolymerization#GO:0031109;plasma membrane bounded cell projection organization#GO:0120036;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;regulation of cytoskeleton organization#GO:0051493;cellular component disassembly#GO:0022411;supramolecular fiber organization#GO:0097435;regulation of microtubule cytoskeleton organization#GO:0070507;neuron differentiation#GO:0030182;cytoskeleton organization#GO:0007010;cellular developmental process#GO:0048869;protein-containing complex disassembly#GO:0032984;regulation of organelle organization#GO:0033043;multicellular organism development#GO:0007275;cellular component organization#GO:0016043;protein depolymerization#GO:0051261;regulation of microtubule polymerization or depolymerization#GO:0031110;cellular process#GO:0009987;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;microtubule-based process#GO:0007017;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;protein-containing complex organization#GO:0043933;anatomical structure development#GO:0048856;biological regulation#GO:0065007;neuron development#GO:0048666;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699 cytoplasm#GO:0005737;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;neuron projection#GO:0043005;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 CIOIN|Ensembl=ENSCING00000019591.1|UniProtKB=H2XQL2 H2XQL2 PTHR10044:SF139 INHIBITOR OF APOPTOSIS DEATH-ASSOCIATED INHIBITOR OF APOPTOSIS 2 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protease inhibitor#PC00191 CIOIN|Ensembl=ENSCING00000024767.1|UniProtKB=H2XS17 H2XS17 PTHR22602:SF0 TRANSFERASE CAF17, MITOCHONDRIAL-RELATED TRANSFERASE CAF17, MITOCHONDRIAL-RELATED cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;iron-sulfur cluster assembly#GO:0016226;cellular process#GO:0009987 CIOIN|Ensembl=ENSCING00000008998.3|UniProtKB=F6PK54 F6PK54 PTHR24113:SF12 RAN GTPASE-ACTIVATING PROTEIN 1 RAN GTPASE-ACTIVATING PROTEIN 1 nucleoside-triphosphatase regulator activity#GO:0060589;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;binding#GO:0005488;molecular function regulator activity#GO:0098772;enzyme binding#GO:0019899;protein binding#GO:0005515;enzyme activator activity#GO:0008047;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234 cellular localization#GO:0051641;regulation of GTPase activity#GO:0043087;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;transport#GO:0006810;activation of GTPase activity#GO:0090630;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;positive regulation of hydrolase activity#GO:0051345;localization#GO:0051179;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;regulation of molecular function#GO:0065009;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;regulation of hydrolase activity#GO:0051336;intracellular transport#GO:0046907;nuclear transport#GO:0051169 cytoplasm#GO:0005737;perinuclear region of cytoplasm#GO:0048471;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 GTPase-activating protein#PC00257 CIOIN|Ensembl=ENSCING00000000589.3|UniProtKB=F6Q0D8 F6Q0D8 PTHR14699:SF0 STI2 PROTEIN-RELATED TETRATRICOPEPTIDE REPEAT PROTEIN 21 HOMOLOG cilium organization#GO:0044782;cellular localization#GO:0051641;macromolecule localization#GO:0033036;cell projection organization#GO:0030030;transport#GO:0006810;microtubule-based movement#GO:0007018;cellular component organization#GO:0016043;cellular process#GO:0009987;intraciliary retrograde transport#GO:0035721;transport along microtubule#GO:0010970;plasma membrane bounded cell projection organization#GO:0120036;intraciliary transport#GO:0042073;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;microtubule-based transport#GO:0099111;cellular macromolecule localization#GO:0070727;protein localization to cilium#GO:0061512;microtubule-based process#GO:0007017;establishment of localization#GO:0051234;organelle organization#GO:0006996;cytoskeleton-dependent intracellular transport#GO:0030705;establishment of localization in cell#GO:0051649;protein localization to organelle#GO:0033365;intracellular transport#GO:0046907;protein-containing complex localization#GO:0031503 intraciliary transport particle A#GO:0030991;protein-containing complex#GO:0032991;intraciliary transport particle#GO:0030990 CIOIN|Ensembl=ENSCING00000005370.3|UniProtKB=F7AVY6 F7AVY6 PTHR19211:SF14 ATP-BINDING TRANSPORT PROTEIN-RELATED ATP-BINDING CASSETTE SUB-FAMILY F MEMBER 1 nucleotide binding#GO:0000166;carbohydrate derivative binding#GO:0097367;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;anion binding#GO:0043168;ATP binding#GO:0005524 translation elongation factor#PC00222;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000024511.1|UniProtKB=H2XZF2 H2XZF2 PTHR45617:SF165 LEUCINE RICH REPEAT FAMILY PROTEIN COMMON DPR-INTERACTING PROTEIN-RELATED scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000007310.3|UniProtKB=F6YK55 F6YK55 PTHR22891:SF174 EUKARYOTIC TRANSLATION INITIATION FACTOR 2C ARGONAUTE-1, ISOFORM A catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;nuclease activity#GO:0004518;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;endonuclease activity#GO:0004519;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity#GO:0016787;RNA nuclease activity#GO:0004540;RNA endonuclease activity#GO:0004521 translation initiation factor#PC00224;translation factor#PC00223 CIOIN|Ensembl=ENSCING00000008294.3|UniProtKB=F6QCP7 F6QCP7 LOC100182373 PTHR31793:SF27 4-HYDROXYBENZOYL-COA THIOESTERASE FAMILY MEMBER NOVEL THIOESTERASE SUPERFAMILY DOMAIN AND SAPOSIN A-TYPE DOMAIN CONTAINING PROTEIN (0610012H03RIK) hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;fatty acyl-CoA hydrolase activity#GO:0047617;catalytic activity#GO:0003824;thiolester hydrolase activity#GO:0016790 esterase#PC00097;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000007189.3|UniProtKB=F6YSE2 F6YSE2 LOC100175780 PTHR14352:SF2 HAUS AUGMIN-LIKE COMPLEX SUBUNIT 7 HAUS AUGMIN-LIKE COMPLEX SUBUNIT 7 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;cellular component organization#GO:0016043;cellular process#GO:0009987;microtubule organizing center organization#GO:0031023;chromosome segregation#GO:0007059;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;spindle assembly#GO:0051225;cytoskeleton organization#GO:0007010;cell cycle#GO:0007049;spindle organization#GO:0007051;non-membrane-bounded organelle assembly#GO:0140694 intracellular non-membrane-bounded organelle#GO:0043232;microtubule associated complex#GO:0005875;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;HAUS complex#GO:0070652;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489 CIOIN|Ensembl=ENSCING00000005360.3|UniProtKB=F6W7Y4 F6W7Y4 PTHR22599:SF21 MPS ONE BINDER KINASE ACTIVATOR-LIKE MOB MOB KINASE ACTIVATOR 2 protein kinase activator activity#GO:0030295;protein kinase regulator activity#GO:0019887;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047;kinase regulator activity#GO:0019207;enzyme regulator activity#GO:0030234;kinase activator activity#GO:0019209 positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of protein modification process#GO:0031401;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;positive regulation of metabolic process#GO:0009893;positive regulation of biological process#GO:0048518;signaling#GO:0023052;positive regulation of protein phosphorylation#GO:0001934;positive regulation of phosphorylation#GO:0042327;cellular response to stimulus#GO:0051716;positive regulation of phosphorus metabolic process#GO:0010562;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;positive regulation of phosphate metabolic process#GO:0045937;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of protein phosphorylation#GO:0001932;biological regulation#GO:0065007;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 kinase modulator#PC00140;kinase activator#PC00138 CIOIN|Ensembl=ENSCING00000003438.3|UniProtKB=F6WYA1 F6WYA1 PTHR24418:SF458 TYROSINE-PROTEIN KINASE TYROSINE-PROTEIN KINASE CSK protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 non-receptor tyrosine protein kinase#PC00168 Integrin signalling pathway#P00034>Csk#P00913;Parkinson disease#P00049>Src kinase#P01230;CCKR signaling map#P06959>CSK#P07072;T cell activation#P00053>Csk#P01304 CIOIN|Ensembl=ENSCING00000019410.1|UniProtKB=F7AS68 F7AS68 PTHR24276:SF91 POLYSERASE-RELATED AT26814P-RELATED hydrolase activity#GO:0016787;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171 serine protease#PC00203;protease#PC00190 CIOIN|Ensembl=ENSCING00000005322.3|UniProtKB=A0A1W2W7Q7 A0A1W2W7Q7 LOC100184567 PTHR10003:SF71 SUPEROXIDE DISMUTASE CU-ZN -RELATED SUPEROXIDE DISMUTASE [CU-ZN] cation binding#GO:0043169;antioxidant activity#GO:0016209;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;transition metal ion binding#GO:0046914;copper ion binding#GO:0005507;metal ion binding#GO:0046872;ion binding#GO:0043167;oxidoreductase activity#GO:0016491 cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;cellular metabolic process#GO:0044237;response to oxidative stress#GO:0006979;cellular process#GO:0009987;response to stimulus#GO:0050896;cellular response to oxygen-containing compound#GO:1901701;detoxification#GO:0098754;response to stress#GO:0006950;response to chemical#GO:0042221;cellular response to oxidative stress#GO:0034599;response to toxic substance#GO:0009636;response to reactive oxygen species#GO:0000302;cellular response to stress#GO:0033554;metabolic process#GO:0008152 oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000008736.3|UniProtKB=A0A1W2W5N9 A0A1W2W5N9 LOC100184699 PTHR13297:SF5 TBC1 DOMAIN FAMILY MEMBER 23-RELATED TBC1 DOMAIN FAMILY MEMBER 23 endosomal transport#GO:0016197;cellular localization#GO:0051641;organelle localization#GO:0051640;vesicle localization#GO:0051648;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;vesicle targeting#GO:0006903;cytosolic transport#GO:0016482;retrograde transport, endosome to Golgi#GO:0042147;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;establishment of organelle localization#GO:0051656 cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;Golgi apparatus subcompartment#GO:0098791;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000007781.3|UniProtKB=F6XSI6 F6XSI6 PTHR24372:SF77 GLYCOPROTEIN HORMONE RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 response to organic substance#GO:0010033;positive regulation of adenylate cyclase activity#GO:0045762;regulation of lyase activity#GO:0051339;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;cellular response to stimulus#GO:0051716;regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;cellular response to endogenous stimulus#GO:0071495;cellular response to chemical stimulus#GO:0070887;positive regulation of catalytic activity#GO:0043085;cellular response to organic substance#GO:0071310;regulation of cyclase activity#GO:0031279;positive regulation of molecular function#GO:0044093;cell communication#GO:0007154;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;positive regulation of cyclase activity#GO:0031281;hormone-mediated signaling pathway#GO:0009755;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to endogenous stimulus#GO:0009719;response to hormone#GO:0009725;cellular response to hormone stimulus#GO:0032870;response to chemical#GO:0042221;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of lyase activity#GO:0051349;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 CIOIN|Ensembl=ENSCING00000021763.1|UniProtKB=H2XUA2 H2XUA2 PTHR11034:SF56 N-MYC DOWNSTREAM REGULATED GH09802P serine protease#PC00203;protease#PC00190 CIOIN|Ensembl=ENSCING00000020906.1|UniProtKB=H2Y058 H2Y058 PTHR15341:SF3 SUN-COR STEROID HORMONE RECEPTOR CO-REPRESSOR NUCLEAR NUCLEIC ACID-BINDING PROTEIN C1D nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;RNA processing#GO:0006396;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;ribosome biogenesis#GO:0042254;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;maturation of 5.8S rRNA#GO:0000460;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;exosome (RNase complex)#GO:0000178 transcription cofactor#PC00217 CIOIN|Ensembl=ENSCING00000004542.3|UniProtKB=F6Y1K6 F6Y1K6 LOC100178587 PTHR11668:SF300 SERINE/THREONINE PROTEIN PHOSPHATASE SERINE_THREONINE-PROTEIN PHOSPHATASE hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;protein serine/threonine phosphatase activity#GO:0004722;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein phosphatase#PC00195;protein modifying enzyme#PC00260 Nicotine pharmacodynamics pathway#P06587>PPP1CA#P06602;Dopamine receptor mediated signaling pathway#P05912>Protein Phosphatase-1#P05969 CIOIN|Ensembl=ENSCING00000022339.1|UniProtKB=H2XQV8 H2XQV8 PTHR16058:SF4 DOUBLE ZINC RIBBON AND ANKYRIN REPEAT-CONTAINING PROTEIN 1 DOUBLE ZINC RIBBON AND ANKYRIN REPEAT-CONTAINING PROTEIN 1 CIOIN|Ensembl=ENSCING00000011404.2|UniProtKB=F7AXU4 F7AXU4 PTHR35836:SF1 VCBS REPEAT-CONTAINING PROTEIN VCBS REPEAT-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000018317.1|UniProtKB=H2Y233 H2Y233 PTHR18847:SF0 20 KD NUCLEAR CAP BINDING PROTEIN NUCLEAR CAP-BINDING PROTEIN SUBUNIT 2 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;RNA cap binding#GO:0000339;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704 intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991 RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000017901.1|UniProtKB=H2Y382 H2Y382 PTHR43779:SF3 DIOXYGENASE RV0097-RELATED (3R)-3-[(CARBOXYMETHYL)AMINO]FATTY ACID OXYGENASE_DECARBOXYLASE oxygenase#PC00177 CIOIN|Ensembl=ENSCING00000013118.2|UniProtKB=F7BNG7 F7BNG7 LOC100177125 PTHR11426:SF191 HISTONE H3 HISTONE H3-LIKE CENTROMERIC PROTEIN A membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 DNA replication#P00017>Histones#P00527 CIOIN|Ensembl=ENSCING00000007103.3|UniProtKB=A0A1W5B6S5 A0A1W5B6S5 LOC100186678 PTHR38563:SF1 FL(2)D-ASSOCIATED COMPLEX COMPONENT FL(2)D-ASSOCIATED COMPLEX COMPONENT CIOIN|Ensembl=ENSCING00000004565.2|UniProtKB=F6XCW6 F6XCW6 LOC100183297 PTHR43968:SF6 FAMILY NOT NAMED GLUTATHIONE S-TRANSFERASE OMEGA cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000008830.3|UniProtKB=F7B0S6 F7B0S6 PTHR24095:SF244 ACETYL-COENZYME A SYNTHETASE ACETYL-COENZYME A SYNTHETASE ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877 cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;amide metabolic process#GO:0043603;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;acyl-CoA metabolic process#GO:0006637;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 ligase#PC00142;metabolite interconversion enzyme#PC00262 Acetate utilization#P02722>Acetyl-CoA synthetase#P02803 CIOIN|Ensembl=ENSCING00000003439.3|UniProtKB=F6WYC4 F6WYC4 PTHR46557:SF1 SERINE/THREONINE-PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 10-RELATED SERINE_THREONINE-PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 10 phosphatase binding#GO:0019902;enzyme binding#GO:0019899;protein binding#GO:0005515;protein phosphatase binding#GO:0019903;binding#GO:0005488 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;protein-DNA complex#GO:0032993;chromosome#GO:0005694;chromatin#GO:0000785;catalytic complex#GO:1902494;protein serine/threonine phosphatase complex#GO:0008287;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 phosphatase modulator#PC00184 CIOIN|Ensembl=ENSCING00000003317.3|UniProtKB=F6TB77 F6TB77 PTHR24115:SF194 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF6 pyrophosphatase activity#GO:0016462;cytoskeletal protein binding#GO:0008092;microtubule motor activity#GO:0003777;tubulin binding#GO:0015631;ATP-dependent activity#GO:0140657;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;cytoskeletal motor activity#GO:0003774;microtubule binding#GO:0008017;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;ribonucleoside triphosphate phosphatase activity#GO:0017111;ATP hydrolysis activity#GO:0016887 microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;microtubule associated complex#GO:0005875;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 CIOIN|Ensembl=ENSCING00000004867.3|UniProtKB=F6TBM3 F6TBM3 LOC100179083 PTHR22420:SF4 PROTEIN FAM81A PROTEIN FAM81A CIOIN|Ensembl=ENSCING00000018331.1|UniProtKB=H2XQE4 H2XQE4 PTHR11735:SF14 TRNA N6-ADENOSINE THREONYLCARBAMOYLTRANSFERASE TRNA N6-ADENOSINE THREONYLCARBAMOYLTRANSFERASE cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 RNA processing factor#PC00147 CIOIN|Ensembl=ENSCING00000020827.1|UniProtKB=H2XU71 H2XU71 PTHR46420:SF1 BETA-1,4-GLUCURONYLTRANSFERASE 1 BETA-1,4-GLUCURONYLTRANSFERASE 1 glucuronosyltransferase activity#GO:0015020;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;UDP-glycosyltransferase activity#GO:0008194 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;protein O-linked glycosylation#GO:0006493;protein O-linked mannosylation#GO:0035269;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;protein mannosylation#GO:0035268;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085;mannosylation#GO:0097502 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000023783.1|UniProtKB=H2XPG9 H2XPG9 LOC100177673 PTHR13149:SF0 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN VPS25 VACUOLAR PROTEIN-SORTING-ASSOCIATED PROTEIN 25 identical protein binding#GO:0042802;protein binding#GO:0005515;binding#GO:0005488 endosomal transport#GO:0016197;cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;protein catabolic process#GO:0030163;late endosome to vacuole transport via multivesicular body sorting pathway#GO:0032511;nitrogen compound transport#GO:0071705;organonitrogen compound catabolic process#GO:1901565;late endosome to vacuole transport#GO:0045324;protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043328;establishment of protein localization#GO:0045184;ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043162;modification-dependent macromolecule catabolic process#GO:0043632;organic substance transport#GO:0071702;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;protein localization to organelle#GO:0033365;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;establishment of protein localization to vacuole#GO:0072666;modification-dependent protein catabolic process#GO:0019941;vacuolar transport#GO:0007034;macromolecule metabolic process#GO:0043170;protein localization to vacuole#GO:0072665;organonitrogen compound metabolic process#GO:1901564;establishment of protein localization to organelle#GO:0072594;vesicle-mediated transport#GO:0016192;multivesicular body sorting pathway#GO:0071985;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein localization#GO:0008104;ubiquitin-dependent protein catabolic process#GO:0006511;localization#GO:0051179;cellular macromolecule localization#GO:0070727;protein transport#GO:0015031;endosome transport via multivesicular body sorting pathway#GO:0032509;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;endosome#GO:0005768;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endosome membrane#GO:0010008;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cytoplasmic vesicle membrane#GO:0030659 membrane traffic protein#PC00150 CIOIN|Ensembl=ENSCING00000008592.3|UniProtKB=F6TQ69 F6TQ69 LOC100175483 PTHR10997:SF18 IMPORTIN-7, 8, 11 D-IMPORTIN 7_RANBP7 cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;protein localization to nucleus#GO:0034504;nitrogen compound transport#GO:0071705;establishment of protein localization to organelle#GO:0072594;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;protein import into nucleus#GO:0006606;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;protein localization to organelle#GO:0033365;intracellular transport#GO:0046907;nuclear transport#GO:0051169;import into nucleus#GO:0051170 envelope#GO:0031975;cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear envelope#GO:0005635;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transporter#PC00227 CIOIN|Ensembl=ENSCING00000001827.3|UniProtKB=F6WIG7 F6WIG7 LOC100180093 PTHR22848:SF0 WD40 REPEAT PROTEIN WD40 REPEAT-CONTAINING PROTEIN SMU1 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;precatalytic spliceosome#GO:0071011;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000019808.1|UniProtKB=A0A1W2WCL1 A0A1W2WCL1 LOC100184402 PTHR22776:SF97 MARVEL-CONTAINING POTENTIAL LIPID RAFT-ASSOCIATED PROTEIN RE01453P cellular anatomical entity#GO:0110165;membrane#GO:0016020 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000024732.1|UniProtKB=H2XZ84 H2XZ84 PTHR35245:SF1 FAMILY NOT NAMED SUBFAMILY NOT NAMED CIOIN|Ensembl=ENSCING00000001209.3|UniProtKB=F6SYW5 F6SYW5 PTHR46088:SF1 TUBULIN--TYROSINE LIGASE-LIKE PROTEIN 12 TUBULIN--TYROSINE LIGASE-LIKE PROTEIN 12 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000000171.3|UniProtKB=F6YYE4 F6YYE4 LOC100180482 PTHR43941:SF1 STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 2 STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 2 CIOIN|Ensembl=ENSCING00000020929.1|UniProtKB=H2XMB9 H2XMB9 LOC101243499 PTHR10031:SF0 ATP SYNTHASE LIPID-BINDING PROTEIN, MITOCHONDRIAL ATPASE PROTEIN 9 cellular aromatic compound metabolic process#GO:0006725;ribonucleoside triphosphate metabolic process#GO:0009199;nucleoside triphosphate metabolic process#GO:0009141;carbohydrate derivative metabolic process#GO:1901135;ATP biosynthetic process#GO:0006754;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ATP metabolic process#GO:0046034;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;purine nucleoside triphosphate biosynthetic process#GO:0009145;heterocycle metabolic process#GO:0046483;purine ribonucleoside triphosphate metabolic process#GO:0009205;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;ribonucleoside triphosphate biosynthetic process#GO:0009201;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;proton motive force-driven ATP synthesis#GO:0015986;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;nucleoside triphosphate biosynthetic process#GO:0009142;organophosphate metabolic process#GO:0019637;purine nucleoside triphosphate metabolic process#GO:0009144;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;proton-transporting two-sector ATPase complex, proton-transporting domain#GO:0033177;ATPase complex#GO:1904949;cellular anatomical entity#GO:0110165;membrane#GO:0016020;proton-transporting ATP synthase complex#GO:0045259;proton-transporting ATP synthase complex, coupling factor F(o)#GO:0045263;proton-transporting two-sector ATPase complex#GO:0016469;intracellular anatomical structure#GO:0005622 ATP synthase#PC00002;primary active transporter#PC00068;transporter#PC00227 CIOIN|Ensembl=ENSCING00000005924.3|UniProtKB=F6ZHQ2 F6ZHQ2 LOC100178332 PTHR47981:SF1 RAB FAMILY RE17845P lysosome organization#GO:0007040;vesicle fusion#GO:0006906;endosomal transport#GO:0016197;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;membrane organization#GO:0061024;phagocytosis#GO:0006909;organelle membrane fusion#GO:0090174;transport#GO:0006810;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;cytosolic transport#GO:0016482;retrograde transport, endosome to Golgi#GO:0042147;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;vacuole organization#GO:0007033;membrane fusion#GO:0061025;establishment of localization#GO:0051234;organelle organization#GO:0006996;phagolysosome assembly#GO:0001845;establishment of localization in cell#GO:0051649;vesicle organization#GO:0016050;intracellular transport#GO:0046907;lytic vacuole organization#GO:0080171;import into cell#GO:0098657;organelle fusion#GO:0048284 endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;organelle#GO:0043226;lytic vacuole#GO:0000323;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;lysosome#GO:0005764;endomembrane system#GO:0012505;phagocytic vesicle#GO:0045335;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endocytic vesicle#GO:0030139;late endosome#GO:0005770 small GTPase#PC00208;G-protein#PC00020 CIOIN|Ensembl=ENSCING00000001920.3|UniProtKB=F6ZJI3 F6ZJI3 PTHR10579:SF172 CALCIUM-ACTIVATED CHLORIDE CHANNEL REGULATOR CALCIUM-ACTIVATED CHLORIDE CHANNEL REGULATOR 4 PRECURSOR-RELATED ion channel#PC00133;transporter#PC00227 CIOIN|Ensembl=ENSCING00000015923.2|UniProtKB=F6YZ74 F6YZ74 LOC104266740 PTHR36732:SF1 GLYCINE RICH PROTEIN 9-RELATED GLYCINE RICH PROTEIN 9-RELATED CIOIN|Ensembl=ENSCING00000007717.3|UniProtKB=F6ZJ82 F6ZJ82 PTHR24014:SF6 2-OXOGLUTARATE AND IRON-DEPENDENT OXYGENASE DOMAIN-CONTAINING PROTEIN 2 PENTATRICOPEPTIDE REPEAT-CONTAINING PROTEIN 1, MITOCHONDRIAL RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000009244.3|UniProtKB=F6W122 F6W122 PTHR12011:SF471 ADHESION G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 2 PROFILE 2 DOMAIN-CONTAINING PROTEIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 CIOIN|Ensembl=ENSCING00000003323.3|UniProtKB=F6SPC1 F6SPC1 PTHR11551:SF13 INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN INSULIN-LIKE GROWTH FACTOR-BINDING PROTEIN 2 protease inhibitor#PC00191;protein-binding activity modulator#PC00095 CIOIN|Ensembl=ENSCING00000005397.3|UniProtKB=F6ZSJ9 F6ZSJ9 PTHR15261:SF4 THROMBOSPONDIN-TYPE LAMININ G DOMAIN AND EAR REPEAT-CONTAINING THROMBOSPONDIN-TYPE LAMININ G DOMAIN AND EAR REPEAT-CONTAINING PROTEIN regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 intercellular signal molecule#PC00207 CIOIN|Ensembl=ENSCING00000002804.3|UniProtKB=F6RKU1 F6RKU1 LOC100175580 PTHR46568:SF1 ALKYLDIHYDROXYACETONEPHOSPHATE SYNTHASE, PEROXISOMAL ALKYLDIHYDROXYACETONEPHOSPHATE SYNTHASE, PEROXISOMAL CIOIN|Ensembl=ENSCING00000020029.1|UniProtKB=H2XNT5 H2XNT5 LOC100184136 PTHR12740:SF4 JNK1/MAPK8-ASSOCIATED MEMBRANE PROTEIN JNK1_MAPK8-ASSOCIATED MEMBRANE PROTEIN enzyme binding#GO:0019899;protein binding#GO:0005515;ubiquitin protein ligase binding#GO:0031625;binding#GO:0005488;ubiquitin-like protein ligase binding#GO:0044389 response to organic substance#GO:0010033;macromolecule catabolic process#GO:0009057;cellular response to stimulus#GO:0051716;response to endoplasmic reticulum stress#GO:0034976;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;response to organonitrogen compound#GO:0010243;ERAD pathway#GO:0036503;cellular process#GO:0009987;primary metabolic process#GO:0044238;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;cellular response to stress#GO:0033554;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000016262.2|UniProtKB=F6ZHL3 F6ZHL3 LOC100182532 PTHR36427:SF3 54S RIBOSOMAL PROTEIN L1, MITOCHONDRIAL LARGE RIBOSOMAL SUBUNIT PROTEIN UL1M ribosomal protein#PC00202;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000007182.3|UniProtKB=F6ZAB8 F6ZAB8 PTHR42985:SF45 SODIUM-COUPLED MONOCARBOXYLATE TRANSPORTER SODIUM_IODIDE COTRANSPORTER-LIKE symporter activity#GO:0015293;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 localization#GO:0051179;monoatomic cation transport#GO:0006812;sodium ion transport#GO:0006814;metal ion transport#GO:0030001;establishment of localization#GO:0051234;monoatomic ion transport#GO:0006811;transport#GO:0006810 secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000009485.3|UniProtKB=F6YSN1 F6YSN1 PTHR16172:SF2 MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 6-LIKE MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 6 cellular anatomical entity#GO:0110165;membrane#GO:0016020 CIOIN|Ensembl=ENSCING00000008621.3|UniProtKB=F6T1Z7 F6T1Z7 LOC100183416 PTHR12062:SF0 N-ACETYLGLUCOSAMINYLTRANSFERASE VI ALPHA-1,3-MANNOSYL-GLYCOPROTEIN 4-BETA-N-ACETYLGLUCOSAMINYLTRANSFERASE B acetylglucosaminyltransferase activity#GO:0008375;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;UDP-glycosyltransferase activity#GO:0008194 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein N-linked glycosylation#GO:0006487;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000009331.3|UniProtKB=F6Z498 F6Z498 PTHR10159:SF519 DUAL SPECIFICITY PROTEIN PHOSPHATASE DUAL SPECIFICITY PROTEIN PHOSPHATASE MPK3 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;dephosphorylation#GO:0016311;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein dephosphorylation#GO:0006470;cellular metabolic process#GO:0044237;cellular process#GO:0009987;protein metabolic process#GO:0019538;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 protein phosphatase#PC00195;protein modifying enzyme#PC00260 Oxidative stress response#P00046>MKP5#P01131 CIOIN|Ensembl=ENSCING00000021395.1|UniProtKB=H2XRY8 H2XRY8 PTHR14211:SF7 GLIOMA SUPPRESSOR CANDIDATE REGION GENE 2 RIBOSOME BIOGENESIS PROTEIN NOP53 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;rRNA binding#GO:0019843;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;RNA processing#GO:0006396;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;ribosomal large subunit biogenesis#GO:0042273;nucleobase-containing compound metabolic process#GO:0006139;protein-RNA complex assembly#GO:0022618;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;ribosomal large subunit assembly#GO:0000027;ribosome biogenesis#GO:0042254;non-membrane-bounded organelle assembly#GO:0140694;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;protein-RNA complex organization#GO:0071826 intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000020186.1|UniProtKB=H2XMP2 H2XMP2 tbx6a PTHR11267:SF204 T-BOX PROTEIN-RELATED SPADETAIL sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cell fate commitment#GO:0045165;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;cell fate specification#GO:0001708;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;Rel homology transcription factor#PC00252;immunoglobulin fold transcription factor#PC00251 CIOIN|Ensembl=ENSCING00000023154.1|UniProtKB=H2XRW5 H2XRW5 PTHR13869:SF24 MYELIN P0 RELATED BASEMENT MEMBRANE-SPECIFIC HEPARAN SULFATE PROTEOGLYCAN CORE PROTEIN-LIKE myelin protein#PC00161;structural protein#PC00211 CIOIN|Ensembl=ENSCING00000018982.1|UniProtKB=Q1RLG5 Q1RLG5 Ci-ZF(C2H2)-66 PTHR14003:SF19 TRANSCRIPTIONAL REPRESSOR PROTEIN YY YY2 TRANSCRIPTION FACTOR sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;PcG protein complex#GO:0031519;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 CIOIN|Ensembl=ENSCING00000008554.3|UniProtKB=F6XPL3 F6XPL3 PTHR24115:SF472 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF3A pyrophosphatase activity#GO:0016462;cytoskeletal protein binding#GO:0008092;microtubule motor activity#GO:0003777;tubulin binding#GO:0015631;ATP-dependent activity#GO:0140657;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;cytoskeletal motor activity#GO:0003774;microtubule binding#GO:0008017;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;ribonucleoside triphosphate phosphatase activity#GO:0017111;ATP hydrolysis activity#GO:0016887 microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;microtubule associated complex#GO:0005875;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 CIOIN|Ensembl=ENSCING00000024294.1|UniProtKB=H2Y1Z7 H2Y1Z7 PTHR20932:SF13 LYSM AND PUTATIVE PEPTIDOGLYCAN-BINDING DOMAIN-CONTAINING PROTEIN LD36653P CIOIN|Ensembl=ENSCING00000004914.3|UniProtKB=F7B8Z8 F7B8Z8 LOC100184622 PTHR46630:SF1 TETRATRICOPEPTIDE REPEAT PROTEIN 29 TETRATRICOPEPTIDE REPEAT PROTEIN 29 CIOIN|Ensembl=ENSCING00000000854.3|UniProtKB=F6R0Q7 F6R0Q7 LOC100187102 PTHR13440:SF7 BLOC-1 RELATED COMPLEX SUBUNIT 6 BLOC-1 RELATED COMPLEX SUBUNIT 6 lysosome localization#GO:0032418;localization#GO:0051179;organelle localization#GO:0051640 intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991 CIOIN|Ensembl=ENSCING00000005039.3|UniProtKB=F6SN53 F6SN53 PTHR14614:SF109 HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN RIBOSOMAL LYSINE N-METHYLTRANSFERASE 5 protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000007886.3|UniProtKB=F6TGF6 F6TGF6 PTHR11733:SF167 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI17812P1-RELATED hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;protein processing#GO:0016485;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 Endothelin signaling pathway#P00019>ECE1-3#P00585 CIOIN|Ensembl=ENSCING00000017420.2|UniProtKB=F6UPP6 F6UPP6 PTHR12434:SF6 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 22 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 22 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mediator complex#GO:0016592;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622 general transcription factor#PC00259 CIOIN|Ensembl=ENSCING00000001138.3|UniProtKB=H2XNT1 H2XNT1 PTHR46613:SF1 RADIAL SPOKE HEAD 10 HOMOLOG B-RELATED RADIAL SPOKE HEAD 10 HOMOLOG B-RELATED CIOIN|Ensembl=ENSCING00000009509.3|UniProtKB=F6XJM1 F6XJM1 LOC100176159 PTHR11365:SF2 5-OXOPROLINASE RELATED 5-OXOPROLINASE hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides#GO:0016812;catalytic activity#GO:0003824 sulfur compound metabolic process#GO:0006790;nitrogen compound metabolic process#GO:0006807;peptide metabolic process#GO:0006518;cellular modified amino acid metabolic process#GO:0006575;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular process#GO:0009987;glutathione metabolic process#GO:0006749;amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000007990.3|UniProtKB=F6W4K8 F6W4K8 PTHR18966:SF575 IONOTROPIC GLUTAMATE RECEPTOR EYE-ENRICHED KAINATE RECEPTOR, ISOFORM B transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;signaling receptor activity#GO:0038023;neurotransmitter receptor activity#GO:0030594;ligand-gated monoatomic ion channel activity#GO:0015276;channel activity#GO:0015267;transporter activity#GO:0005215;transmembrane signaling receptor activity#GO:0004888;glutamate receptor activity#GO:0008066;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;molecular transducer activity#GO:0060089;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;ligand-gated channel activity#GO:0022834 regulation of cell communication#GO:0010646;regulation of signaling#GO:0023051;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;anterograde trans-synaptic signaling#GO:0098916;chemical synaptic transmission#GO:0007268;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;synaptic signaling#GO:0099536;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;synaptic transmission, glutamatergic#GO:0035249;signaling#GO:0023052;cell-cell signaling#GO:0007267 synapse#GO:0045202;postsynaptic specialization#GO:0099572;postsynaptic density#GO:0014069;postsynaptic membrane#GO:0045211;cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;neuron to neuron synapse#GO:0098984;membrane#GO:0016020;synaptic membrane#GO:0097060;asymmetric synapse#GO:0032279;postsynaptic specialization membrane#GO:0099634;postsynaptic density membrane#GO:0098839;plasma membrane region#GO:0098590;postsynapse#GO:0098794;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 CIOIN|Ensembl=ENSCING00000003195.3|UniProtKB=F6SQ79 F6SQ79 rhysin2_deltex3-c PTHR12622:SF45 DELTEX-RELATED RING-TYPE E3 UBIQUITIN TRANSFERASE transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein ubiquitination#GO:0016567;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cell communication#GO:0007154;cellular process#GO:0009987;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;nitrogen compound metabolic process#GO:0006807;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;signaling#GO:0023052;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;Notch signaling pathway#GO:0007219 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000015530.2|UniProtKB=F6T7Z6 F6T7Z6 LOC100185925 PTHR44147:SF2 DEHYDROGENASE/REDUCTASE SDR FAMILY MEMBER 1 DEHYDROGENASE_REDUCTASE SDR FAMILY MEMBER 1 dehydrogenase#PC00092;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000011954.2|UniProtKB=F6UKH7 F6UKH7 LOC100184038 PTHR10279:SF10 ORNITHINE DECARBOXYLASE ANTIZYME ORNITHINE DECARBOXYLASE ANTIZYME enzyme inhibitor activity#GO:0004857;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of protein metabolic process#GO:0051246;regulation of catabolic process#GO:0009894;regulation of nitrogen compound metabolic process#GO:0051171;regulation of protein catabolic process#GO:0042176;positive regulation of macromolecule metabolic process#GO:0010604;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;positive regulation of protein metabolic process#GO:0051247;positive regulation of metabolic process#GO:0009893;regulation of macromolecule metabolic process#GO:0060255;positive regulation of catabolic process#GO:0009896;biological regulation#GO:0065007;positive regulation of protein catabolic process#GO:0045732;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein-binding activity modulator#PC00095 CIOIN|Ensembl=ENSCING00000007443.3|UniProtKB=F7ANS1 F7ANS1 PTHR11662:SF399 SOLUTE CARRIER FAMILY 17 FI19708P1-RELATED secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000001620.3|UniProtKB=F7B8G8 F7B8G8 LOC100185811 PTHR11353:SF22 CHAPERONIN T-COMPLEX PROTEIN 1 SUBUNIT ETA protein binding#GO:0005515;unfolded protein binding#GO:0051082;binding#GO:0005488 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein folding#GO:0006457;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;chaperonin-containing T-complex#GO:0005832;protein folding chaperone complex#GO:0101031;intracellular anatomical structure#GO:0005622 chaperonin#PC00073 CIOIN|Ensembl=ENSCING00000010559.3|UniProtKB=H2XYB4 H2XYB4 PTHR13405:SF11 NUCLEAR PORE COMPLEX PROTEIN NUP133 NUCLEAR PORE COMPLEX PROTEIN NUP133 structural molecule activity#GO:0005198;structural constituent of nuclear pore#GO:0017056 cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;protein localization to nucleus#GO:0034504;nucleic acid transport#GO:0050657;nitrogen compound transport#GO:0071705;gene expression#GO:0010467;biosynthetic process#GO:0009058;establishment of protein localization#GO:0045184;RNA localization#GO:0006403;organic substance transport#GO:0071702;protein import into nucleus#GO:0006606;transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery#GO:0000972;establishment of localization#GO:0051234;RNA transport#GO:0050658;protein localization to organelle#GO:0033365;nuclear transport#GO:0051169;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;poly(A)+ mRNA export from nucleus#GO:0016973;mRNA export from nucleus#GO:0006406;macromolecule biosynthetic process#GO:0009059;establishment of RNA localization#GO:0051236;macromolecule metabolic process#GO:0043170;establishment of protein localization to organelle#GO:0072594;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;mRNA transport#GO:0051028;cellular process#GO:0009987;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;nuclear export#GO:0051168;nucleocytoplasmic transport#GO:0006913;organelle organization#GO:0006996;chromosome organization#GO:0051276;nucleobase-containing compound transport#GO:0015931;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;import into nucleus#GO:0051170 envelope#GO:0031975;nuclear pore#GO:0005643;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear envelope#GO:0005635;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;organelle envelope#GO:0031967;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000024810.1|UniProtKB=H2XTC8 H2XTC8 PTHR43437:SF3 HYDROXYACYL-THIOESTER DEHYDRATASE TYPE 2, MITOCHONDRIAL-RELATED HYDROXYACYL-THIOESTER DEHYDRATASE TYPE 2, MITOCHONDRIAL carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829;catalytic activity#GO:0003824;hydro-lyase activity#GO:0016836 organic acid biosynthetic process#GO:0016053;lipid metabolic process#GO:0006629;oxoacid metabolic process#GO:0043436;monocarboxylic acid biosynthetic process#GO:0072330;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;fatty acid metabolic process#GO:0006631;small molecule biosynthetic process#GO:0044283;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;fatty acid biosynthetic process#GO:0006633;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 dehydratase#PC00091;lyase#PC00144 CIOIN|Ensembl=ENSCING00000004250.3|UniProtKB=F6UZ70 F6UZ70 LOC100185570 PTHR11482:SF6 ARGININE/DIAMINOPIMELATE/ORNITHINE DECARBOXYLASE ORNITHINE DECARBOXYLASE 1-RELATED lyase activity#GO:0016829;carboxy-lyase activity#GO:0016831;carbon-carbon lyase activity#GO:0016830;catalytic activity#GO:0003824 amine metabolic process#GO:0009308;oxoacid metabolic process#GO:0043436;biogenic amine metabolic process#GO:0006576;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;polyamine metabolic process#GO:0006595;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;alpha-amino acid metabolic process#GO:1901605;polyamine biosynthetic process#GO:0006596;carboxylic acid metabolic process#GO:0019752;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 decarboxylase#PC00089 Ornithine degradation#P02758>Ornithine decarboxylase#P03053 CIOIN|Ensembl=ENSCING00000020728.1|UniProtKB=A0A1W2WHS9 A0A1W2WHS9 LOC100179384 PTHR11907:SF0 AMIDOPHOSPHORIBOSYLTRANSFERASE AMIDOPHOSPHORIBOSYLTRANSFERASE transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;pentosyltransferase activity#GO:0016763;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 transferase#PC00220;metabolite interconversion enzyme#PC00262 De novo purine biosynthesis#P02738>Amidophosphoribosyl transferase#P02905 CIOIN|Ensembl=ENSCING00000004939.3|UniProtKB=F6X9G8 F6X9G8 PTHR11533:SF301 PROTEASE M1 ZINC METALLOPROTEASE AMINOPEPTIDASE metalloexopeptidase activity#GO:0008235;metallopeptidase activity#GO:0008237;small molecule binding#GO:0036094;zinc ion binding#GO:0008270;binding#GO:0005488;catalytic activity#GO:0003824;transition metal ion binding#GO:0046914;amide binding#GO:0033218;metal ion binding#GO:0046872;peptidase activity#GO:0008233;metalloaminopeptidase activity#GO:0070006;cation binding#GO:0043169;peptide binding#GO:0042277;hydrolase activity#GO:0016787;aminopeptidase activity#GO:0004177;exopeptidase activity#GO:0008238;ion binding#GO:0043167;catalytic activity, acting on a protein#GO:0140096 macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;peptide catabolic process#GO:0043171;cellular process#GO:0009987;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;membrane#GO:0016020;extracellular region#GO:0005576;intracellular anatomical structure#GO:0005622 metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000006425.3|UniProtKB=F6QS20 F6QS20 PTHR10223:SF0 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 4 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 4 protein binding#GO:0005515;binding#GO:0005488;polyubiquitin modification-dependent protein binding#GO:0031593;modification-dependent protein binding#GO:0140030 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 peptidase complex#GO:1905368;proteasome accessory complex#GO:0022624;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;proteasome regulatory particle#GO:0005838;catalytic complex#GO:1902494;proteasome complex#GO:0000502;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endopeptidase complex#GO:1905369;membrane-bounded organelle#GO:0043227 protease#PC00190;protein modifying enzyme#PC00260 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489;Cell cycle#P00013>Proteasome#P00480 CIOIN|Ensembl=ENSCING00000001999.3|UniProtKB=F6WTG3 F6WTG3 PTHR24012:SF690 RNA BINDING PROTEIN BRUNO 3, ISOFORM Q nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000008190.3|UniProtKB=F6VDF0 F6VDF0 PTHR10824:SF4 ACYL-COENZYME A THIOESTERASE-RELATED ACYL-COENZYME A THIOESTERASE 1-LIKE hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;fatty acyl-CoA hydrolase activity#GO:0047617;catalytic activity#GO:0003824;thiolester hydrolase activity#GO:0016790 cellular aromatic compound metabolic process#GO:0006725;lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;amide metabolic process#GO:0043603;purine nucleotide metabolic process#GO:0006163;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;acyl-CoA metabolic process#GO:0006637;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;ribonucleotide metabolic process#GO:0009259;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;purine ribonucleotide metabolic process#GO:0009150;fatty acid metabolic process#GO:0006631;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 esterase#PC00097 CIOIN|Ensembl=ENSCING00000003611.3|UniProtKB=L7N0R5 L7N0R5 PTHR43802:SF1 ENOYL-COA HYDRATASE IP11341P-RELATED lyase#PC00144;hydratase#PC00120 CIOIN|Ensembl=ENSCING00000007867.3|UniProtKB=F6ST26 F6ST26 PTHR11523:SF28 SODIUM/POTASSIUM-DEPENDENT ATPASE BETA SUBUNIT NA_K-ATPASE BETA SUBUNIT ISOFORM 4-RELATED molecular function activator activity#GO:0140677;ATPase activator activity#GO:0001671;molecular function regulator activity#GO:0098772 inorganic ion homeostasis#GO:0098771;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;sodium ion homeostasis#GO:0055078;monoatomic cation homeostasis#GO:0055080;homeostatic process#GO:0042592;inorganic ion transmembrane transport#GO:0098660;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;cellular process#GO:0009987;intracellular chemical homeostasis#GO:0055082;monoatomic ion homeostasis#GO:0050801;localization#GO:0051179;import across plasma membrane#GO:0098739;sodium ion transport#GO:0006814;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;intracellular monoatomic cation homeostasis#GO:0030003;potassium ion transmembrane transport#GO:0071805;monoatomic cation transport#GO:0006812;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion transport#GO:0006811;import into cell#GO:0098657;monoatomic cation transmembrane transport#GO:0098655;export from cell#GO:0140352;sodium ion transmembrane transport#GO:0035725;potassium ion import across plasma membrane#GO:1990573;potassium ion transport#GO:0006813 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 primary active transporter#PC00068;transporter#PC00227 CIOIN|Ensembl=ENSCING00000003844.3|UniProtKB=F6YQM8 F6YQM8 PTHR10913:SF81 FOLLISTATIN-RELATED KAZAL-LIKE DOMAIN-CONTAINING PROTEIN regulation of cell communication#GO:0010646;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;regulation of signaling#GO:0023051;developmental process#GO:0032502;cellular process#GO:0009987;regulation of BMP signaling pathway#GO:0030510;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;cell differentiation#GO:0030154;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;anatomical structure development#GO:0048856;biological regulation#GO:0065007;regulation of cellular response to growth factor stimulus#GO:0090287;multicellular organismal process#GO:0032501 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 protease inhibitor#PC00191 CIOIN|Ensembl=ENSCING00000009748.3|UniProtKB=F7ACA9 F7ACA9 LOC100182979 PTHR24347:SF454 SERINE/THREONINE-PROTEIN KINASE PHOSPHORYLASE KINASE non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Phosphorylase b kinase#P00716 CIOIN|Ensembl=ENSCING00000022214.1|UniProtKB=H2Y281 H2Y281 PTHR46350:SF2 RAS LIKE FAMILY 10 MEMBER B-RELATED RAS LIKE FAMILY 10 MEMBER B CIOIN|Ensembl=ENSCING00000003716.3|UniProtKB=F6WV27 F6WV27 PTHR14969:SF28 SPHINGOSINE-1-PHOSPHATE PHOSPHOHYDROLASE DIHYDROSPHINGOSINE 1-PHOSPHATE PHOSPHATASE LCB3-RELATED hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;phosphatase#PC00181;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000025189.1|UniProtKB=H2XX57 H2XX57 PTHR47160:SF10 PUTATIVE-RELATED MULE TRANSPOSASE DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000007913.4|UniProtKB=F7AAE8 F7AAE8 PTHR18806:SF4 RBM25 PROTEIN RNA-BINDING PROTEIN 25 CIOIN|Ensembl=ENSCING00000000770.3|UniProtKB=F6PH64 F6PH64 PTHR24031:SF68 RNA HELICASE ATP-DEPENDENT RNA HELICASE DDX51 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA helicase#PC00032 CIOIN|Ensembl=ENSCING00000024005.1|UniProtKB=H2XL75 H2XL75 PTHR24391:SF18 HISTONE H4 TRANSCRIPTION FACTOR-RELATED EG:115C2.6 PROTEIN C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 CIOIN|Ensembl=ENSCING00000014541.2|UniProtKB=F6V014 F6V014 PTHR45828:SF33 CYTOCHROME B561/FERRIC REDUCTASE TRANSMEMBRANE DOMON DOMAIN-CONTAINING PROTEIN cellular anatomical entity#GO:0110165;membrane#GO:0016020 reductase#PC00198;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000013263.2|UniProtKB=F6SFE9 F6SFE9 PTHR45807:SF7 TYROSINE-PROTEIN KINASE HOPSCOTCH TYROSINE-PROTEIN KINASE HOPSCOTCH non-receptor tyrosine protein kinase#PC00168 CIOIN|Ensembl=ENSCING00000024342.1|UniProtKB=H2Y093 H2Y093 PTHR16024:SF6 XK-RELATED PROTEIN XK-RELATED PROTEIN secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000008951.3|UniProtKB=F6Q643 F6Q643 PTHR45834:SF3 RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 9-RELATED RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 3, ISOFORM L nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;guanyl-nucleotide exchange factor activity#GO:0005085 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 CIOIN|Ensembl=ENSCING00000010405.3|UniProtKB=F6R701 F6R701 PTHR24412:SF497 KELCH PROTEIN KELCH-LIKE PROTEIN 18 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000021342.1|UniProtKB=H2XRI7 H2XRI7 PTHR23002:SF117 ZINC FINGER CCHC DOMAIN CONTAINING PROTEIN CCHC-TYPE ZINC FINGER, NUCLEIC ACID-BINDING PROTEIN A-RELATED nucleic acid binding#GO:0003676;single-stranded RNA binding#GO:0003727;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 positive regulation of gene expression#GO:0010628;positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of protein metabolic process#GO:0051246;regulation of amide metabolic process#GO:0034248;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;positive regulation of biosynthetic process#GO:0009891;positive regulation of protein metabolic process#GO:0051247;positive regulation of metabolic process#GO:0009893;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biosynthetic process#GO:0009889;post-transcriptional regulation of gene expression#GO:0010608;positive regulation of macromolecule biosynthetic process#GO:0010557;biological regulation#GO:0065007;regulation of translation#GO:0006417;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of biological process#GO:0048518;positive regulation of translation#GO:0045727;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000018886.1|UniProtKB=H2XJS6 H2XJS6 LOC100183593 PTHR11511:SF4 LARVAL STORAGE PROTEIN/PHENOLOXIDASE PHENOLOXIDASE 2-RELATED CIOIN|Ensembl=ENSCING00000008460.3|UniProtKB=F6V7W7 F6V7W7 PTHR45734:SF10 TENSIN BLISTERY, ISOFORM A cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165 CIOIN|Ensembl=ENSCING00000010002.3|UniProtKB=F6QM76 F6QM76 PTHR34400:SF4 FAMILY NOT NAMED MEMBRANE PROTEIN CIOIN|Ensembl=ENSCING00000008818.3|UniProtKB=H2XPL3 H2XPL3 PTHR10829:SF25 CORTACTIN AND DREBRIN DREBRIN-LIKE PROTEIN cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 regulation of anatomical structure size#GO:0090066;regulation of actin filament length#GO:0030832;regulation of organelle organization#GO:0033043;regulation of actin filament organization#GO:0110053;regulation of cellular component organization#GO:0051128;cellular component organization#GO:0016043;regulation of actin polymerization or depolymerization#GO:0008064;cellular process#GO:0009987;regulation of actin filament polymerization#GO:0030833;regulation of cellular component size#GO:0032535;regulation of supramolecular fiber organization#GO:1902903;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of cytoskeleton organization#GO:0051493;regulation of protein-containing complex assembly#GO:0043254;regulation of biological quality#GO:0065008;regulation of cellular process#GO:0050794;regulation of cellular component biogenesis#GO:0044087;biological regulation#GO:0065007;regulation of actin cytoskeleton organization#GO:0032956;regulation of actin filament-based process#GO:0032970;regulation of protein polymerization#GO:0032271 supramolecular complex#GO:0099080;cortical cytoskeleton#GO:0030863;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;cell cortex#GO:0005938;cell periphery#GO:0071944;supramolecular fiber#GO:0099512;cortical actin cytoskeleton#GO:0030864;organelle#GO:0043226;actin filament#GO:0005884;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cytoskeleton#GO:0005856 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041;non-motor actin binding protein#PC00165 CIOIN|Ensembl=ENSCING00000011512.2|UniProtKB=F6WU27 F6WU27 PTHR45570:SF2 CARBOXYLIC ESTER HYDROLASE ACETYLCHOLINESTERASE 1-LIKE metabolite interconversion enzyme#PC00262;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000020874.1|UniProtKB=H2Y2B7 H2Y2B7 PTHR10582:SF2 TRANSIENT RECEPTOR POTENTIAL ION CHANNEL PROTEIN INACTIVE passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic ion channel activity#GO:0005216;channel activity#GO:0015267;monoatomic ion transmembrane transporter activity#GO:0015075 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;calcium ion transmembrane transport#GO:0070588;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;calcium ion transport#GO:0006816;calcium ion import#GO:0070509;localization#GO:0051179;import across plasma membrane#GO:0098739;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;calcium ion transmembrane import into cytosol#GO:0097553;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;import into cell#GO:0098657;monoatomic cation transmembrane transport#GO:0098655 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 CIOIN|Ensembl=ENSCING00000019112.1|UniProtKB=A0A1W5BRK9 A0A1W5BRK9 LOC100179621 PTHR21614:SF0 SHORT COILED COIL PROTEIN GEO08385P1 cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;Golgi apparatus subcompartment#GO:0098791;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000021807.1|UniProtKB=H2XZ52 H2XZ52 PTHR46197:SF3 PROTEIN ABHD14B-LIKE AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000004188.3|UniProtKB=F7B573 F7B573 mina53-like1 PTHR12461:SF52 HYPOXIA-INDUCIBLE FACTOR 1 ALPHA INHIBITOR-RELATED JMJC DOMAIN-CONTAINING PROTEIN protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000008257.3|UniProtKB=F6QZ12 F6QZ12 PTHR16055:SF2 INTEGRATOR COMPLEX SUBUNIT 10 INTEGRATOR COMPLEX SUBUNIT 10 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;snRNA metabolic process#GO:0016073;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;snRNA processing#GO:0016180;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;integrator complex#GO:0032039 CIOIN|Ensembl=ENSCING00000002177.3|UniProtKB=F6SS76 F6SS76 LOC100179977 PTHR17602:SF4 RIBOSOME BIOGENESIS REGULATORY PROTEIN RIBOSOME BIOGENESIS REGULATORY PROTEIN HOMOLOG cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;RNA processing#GO:0006396;gene expression#GO:0010467;biosynthetic process#GO:0009058;ribosomal large subunit biogenesis#GO:0042273;nucleobase-containing compound metabolic process#GO:0006139;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;ribosome biogenesis#GO:0042254;maturation of 5.8S rRNA#GO:0000460;endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000447;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;maturation of SSU-rRNA#GO:0030490;ribosomal small subunit biogenesis#GO:0042274 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;preribosome, large subunit precursor#GO:0030687;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;nuclear lumen#GO:0031981 ribosomal protein#PC00202;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000024053.1|UniProtKB=H2XL55 H2XL55 LOC100187471 PTHR23355:SF35 RIBONUCLEASE EXOSOME COMPLEX EXONUCLEASE RRP44 catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;catalytic activity#GO:0003824;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters#GO:0016796;endonuclease activity#GO:0004519;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity#GO:0016787;3'-5'-RNA exonuclease activity#GO:0000175;3'-5' exonuclease activity#GO:0008408;exonuclease activity#GO:0004527;RNA nuclease activity#GO:0004540 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;heterocycle catabolic process#GO:0046700;RNA metabolic process#GO:0016070;nucleobase-containing compound metabolic process#GO:0006139;cellular nitrogen compound catabolic process#GO:0044270;regulation of biological process#GO:0050789;ncRNA metabolic process#GO:0034660;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;mRNA catabolic process#GO:0006402;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance catabolic process#GO:1901575;negative regulation of cellular process#GO:0048523;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;negative regulation of biosynthetic process#GO:0009890;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;nuclear-transcribed mRNA catabolic process#GO:0000956;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;rRNA metabolic process#GO:0016072;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;nucleobase-containing compound catabolic process#GO:0034655;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513;exosome (RNase complex)#GO:0000178 RNA metabolism protein#PC00031;exoribonuclease#PC00099 CIOIN|Ensembl=ENSCING00000006874.3|UniProtKB=F6ZCT8 F6ZCT8 PTHR45752:SF196 LEUCINE-RICH REPEAT-CONTAINING GH17740P scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000007055.3|UniProtKB=F6U7B2 F6U7B2 LOC100179720 PTHR24409:SF413 ZINC FINGER PROTEIN 142 DATILOGRAFO, ISOFORM A-RELATED sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 CIOIN|Ensembl=ENSCING00000000898.3|UniProtKB=F6U1J3 F6U1J3 LOC100184348 PTHR10041:SF9 COLIPASE COLIPASE protein-binding activity modulator#PC00095 CIOIN|Ensembl=ENSCING00000003734.3|UniProtKB=F6U6Z4 F6U6Z4 PTHR19237:SF20 NUCLEOBINDIN NUCLEOBINDIN 1 cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;extracellular region#GO:0005576;membrane-bounded organelle#GO:0043227;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 calmodulin-related#PC00061 CIOIN|Ensembl=ENSCING00000009128.4|UniProtKB=F6S3E0 F6S3E0 LOC113474074 PTHR43108:SF6 N-ACETYLGLUCOSAMINE-6-SULFATASE FAMILY MEMBER N-SULPHOGLUCOSAMINE SULPHOHYDROLASE metabolite interconversion enzyme#PC00262;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000006374.3|UniProtKB=F6REQ0 F6REQ0 PTHR24064:SF445 SOLUTE CARRIER FAMILY 22 MEMBER AT15560P-RELATED secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000006711.3|UniProtKB=Q1RL50 Q1RL50 Ci-ArfGAP-11 PTHR45854:SF3 ASAP FAMILY MEMBER ARFGAP WITH SH3 DOMAIN, ANK REPEAT AND PH DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000001387.3|UniProtKB=F6ZTT3 F6ZTT3 PTHR11309:SF35 FRIZZLED PROTEIN SMOOTHENED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;protein binding#GO:0005515;Wnt-protein binding#GO:0017147;signaling receptor binding#GO:0005102;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 neuron projection guidance#GO:0097485;signal transduction#GO:0007165;neurogenesis#GO:0022008;cell projection organization#GO:0030030;smoothened signaling pathway#GO:0007224;developmental process#GO:0032502;non-canonical Wnt signaling pathway#GO:0035567;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cellular anatomical entity morphogenesis#GO:0032989;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;axon guidance#GO:0007411;anatomical structure morphogenesis#GO:0009653;neuron differentiation#GO:0030182;central nervous system development#GO:0007417;axonogenesis#GO:0007409;plasma membrane bounded cell projection morphogenesis#GO:0120039;pattern specification process#GO:0007389;cell-cell signaling#GO:0007267;signaling#GO:0023052;canonical Wnt signaling pathway#GO:0060070;Wnt signaling pathway#GO:0016055;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;multicellular organism development#GO:0007275;cell communication#GO:0007154;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;cellular process#GO:0009987;cell-cell signaling by wnt#GO:0198738;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;response to stimulus#GO:0050896;axon development#GO:0061564;cell morphogenesis involved in neuron differentiation#GO:0048667;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;anatomical structure development#GO:0048856;biological regulation#GO:0065007;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699 somatodendritic compartment#GO:0036477;neuron projection#GO:0043005;dendrite#GO:0030425;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;cilium#GO:0005929;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Hedgehog signaling pathway#P00025>Smoothened#P00685 CIOIN|Ensembl=ENSCING00000017291.2|UniProtKB=F7A0D6 F7A0D6 PTHR21661:SF35 EPOXIDE HYDROLASE 1-RELATED EPOXIDE HYDROLASE hydrolase activity#GO:0016787;catalytic activity#GO:0003824 cellular metabolic process#GO:0044237;heterocycle metabolic process#GO:0046483;organic cyclic compound metabolic process#GO:1901360;cellular process#GO:0009987;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000005016.3|UniProtKB=F6TXS1 F6TXS1 PTHR16299:SF2 CENTROSOMAL PROTEIN KIZUNA CENTROSOMAL PROTEIN KIZUNA CIOIN|Ensembl=ENSCING00000018955.1|UniProtKB=H2XL53 H2XL53 LOC100185846 PTHR46334:SF1 COSTARS FAMILY PROTEIN ABRACL COSTARS FAMILY PROTEIN ABRACL biological regulation#GO:0065007;regulation of biological process#GO:0050789;regulation of actin filament-based process#GO:0032970;regulation of cellular process#GO:0050794 CIOIN|Ensembl=ENSCING00000009419.3|UniProtKB=A0A1W3JPZ4 A0A1W3JPZ4 LOC100183888 PTHR23284:SF0 PROLACTIN REGULATORY ELEMENT BINDING PROTEIN PROLACTIN REGULATORY ELEMENT-BINDING PROTEIN endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;regulation of organelle organization#GO:0033043;transport#GO:0006810;vesicle-mediated transport#GO:0016192;regulation of cellular component organization#GO:0051128;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987;regulation of biological process#GO:0050789;localization#GO:0051179;regulation of protein-containing complex assembly#GO:0043254;establishment of localization#GO:0051234;regulation of cellular process#GO:0050794;regulation of cellular component biogenesis#GO:0044087;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 CIOIN|Ensembl=ENSCING00000000628.3|UniProtKB=F6VIZ2 F6VIZ2 mef2 PTHR11945:SF534 MADS BOX PROTEIN MYOCYTE-SPECIFIC ENHANCER FACTOR 2 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 MADS box transcription factor#PC00250 p38 MAPK pathway#P05918>MEF#P06023;Oxidative stress response#P00046>MEF-2#P01128 CIOIN|Ensembl=ENSCING00000006087.3|UniProtKB=F6ZFJ3 F6ZFJ3 LOC100179705 PTHR14568:SF8 TRANSMEMBRANE SUPERFAMILY 6 MEMBER 1/2 EXPERA DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000005255.3|UniProtKB=F6V9R6 F6V9R6 LOC100180614 PTHR23301:SF0 CHITIN BINDING PERITROPHIN-A CHITIN-BINDING TYPE-2 DOMAIN-CONTAINING PROTEIN-RELATED CIOIN|Ensembl=ENSCING00000016963.2|UniProtKB=F7AJI6 F7AJI6 PTHR11515:SF13 GLYCOPROTEIN HORMONE BETA CHAIN GLYCOPROTEIN HORMONE BETA 5, ISOFORM A regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576;intracellular anatomical structure#GO:0005622 peptide hormone#PC00179 CIOIN|Ensembl=ENSCING00000023570.1|UniProtKB=H2XR92 H2XR92 PTHR43248:SF3 2-SUCCINYL-6-HYDROXY-2,4-CYCLOHEXADIENE-1-CARBOXYLATE SYNTHASE AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN metabolite interconversion enzyme#PC00262;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000008959.3|UniProtKB=F6Q5U4 F6Q5U4 PTHR11774:SF4 GERANYLGERANYL TRANSFERASE TYPE BETA SUBUNIT GERANYLGERANYL TRANSFERASE TYPE-1 SUBUNIT BETA prenyltransferase activity#GO:0004659;transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein modification process#GO:0036211;cellular process#GO:0009987;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;transferase complex#GO:1990234 acyltransferase#PC00042;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000014430.2|UniProtKB=Q4H2Q4 Q4H2Q4 Ci-TCFL1 PTHR13275:SF4 YL-1 PROTEIN TRANSCRIPTION FACTOR-LIKE 1 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 72 HOMOLOG membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218 CIOIN|Ensembl=ENSCING00000001649.3|UniProtKB=F6YIE7 F6YIE7 tgfbr-ia PTHR23255:SF72 TRANSFORMING GROWTH FACTOR-BETA RECEPTOR TYPE I AND II RECEPTOR PROTEIN SERINE_THREONINE KINASE macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;phosphorylation#GO:0016310;protein phosphorylation#GO:0006468;cellular process#GO:0009987;protein metabolic process#GO:0019538;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 serine/threonine protein kinase receptor#PC00205 GBB signaling pathway#P06214>SAX#P06307;TGF-beta signaling pathway#P00052>TGFbetareceptors#P01283;TGF-beta signaling pathway#P00052>TGFbetareceptor I#P01278;DPP-SCW signaling pathway#P06212>SAX#P06274;BMP/activin signaling pathway-drosophila#P06211>TGFbetaR I#P06241;SCW signaling pathway#P06216>SAX#P06329 CIOIN|Ensembl=ENSCING00000003264.3|UniProtKB=F6WP04 F6WP04 PTHR24247:SF265 5-HYDROXYTRYPTAMINE RECEPTOR MUSCARINIC ACETYLCHOLINE RECEPTOR DM1 signaling receptor activity#GO:0038023;G protein-coupled amine receptor activity#GO:0008227;molecular transducer activity#GO:0060089;neurotransmitter receptor activity#GO:0030594;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 response to organic substance#GO:0010033;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to nitrogen compound#GO:1901699;response to nitrogen compound#GO:1901698;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to oxygen-containing compound#GO:1901701;chemical synaptic transmission#GO:0007268;response to chemical#GO:0042221;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;synaptic signaling#GO:0099536;G protein-coupled receptor signaling pathway#GO:0007186;cell-cell signaling#GO:0007267;signaling#GO:0023052;acetylcholine receptor signaling pathway#GO:0095500 synapse#GO:0045202;somatodendritic compartment#GO:0036477;neuron projection#GO:0043005;cell junction#GO:0030054;dendrite#GO:0030425;cell projection#GO:0042995;cell periphery#GO:0071944;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GqPCR#P00730 CIOIN|Ensembl=ENSCING00000011632.2|UniProtKB=F7A726 F7A726 LOC100177487 PTHR10983:SF73 1-ACYLGLYCEROL-3-PHOSPHATE ACYLTRANSFERASE-RELATED 1-ACYL-SN-GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE EPSILON transferase activity#GO:0016740;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;glycerolipid metabolic process#GO:0046486;cellular metabolic process#GO:0044237;phosphatidylinositol metabolic process#GO:0046488;organophosphate metabolic process#GO:0019637;glycerophospholipid metabolic process#GO:0006650;cellular process#GO:0009987;phospholipid metabolic process#GO:0006644;cellular lipid metabolic process#GO:0044255;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 acyltransferase#PC00042 CIOIN|Ensembl=ENSCING00000009162.3|UniProtKB=H2XRE3 H2XRE3 LOC100182613 PTHR44281:SF2 SPINDLE ASSEMBLY ABNORMAL PROTEIN 6 HOMOLOG SPINDLE ASSEMBLY ABNORMAL PROTEIN 6 HOMOLOG CIOIN|Ensembl=ENSCING00000005126.3|UniProtKB=F6ZIF2 F6ZIF2 PTHR23115:SF301 TRANSLATION FACTOR ELONGATION FACTOR 1-ALPHA GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;nucleic acid binding#GO:0003676;translation regulator activity#GO:0045182;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;translation regulator activity, nucleic acid binding#GO:0090079;translation elongation factor activity#GO:0003746;translation factor activity, RNA binding#GO:0008135 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;translational elongation#GO:0006414;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 translation factor#PC00223;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000005935.3|UniProtKB=F6YYY1 F6YYY1 PTHR45755:SF1 FAMILY NOT NAMED PROTON-COUPLED ZINC ANTIPORTER SLC30A5 inorganic molecular entity transmembrane transporter activity#GO:0015318;transmembrane transporter activity#GO:0022857;monoatomic cation transmembrane transporter activity#GO:0008324;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;inorganic cation transmembrane transporter activity#GO:0022890;metal ion transmembrane transporter activity#GO:0046873 inorganic ion homeostasis#GO:0098771;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;homeostatic process#GO:0042592;monoatomic cation homeostasis#GO:0055080;inorganic ion transmembrane transport#GO:0098660;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;cellular process#GO:0009987;intracellular chemical homeostasis#GO:0055082;monoatomic ion homeostasis#GO:0050801;localization#GO:0051179;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation transport#GO:0006812;transition metal ion transport#GO:0000041;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000002813.3|UniProtKB=F6WCR1 F6WCR1 LOC100178968 PTHR10322:SF23 DNA POLYMERASE CATALYTIC SUBUNIT DNA POLYMERASE DELTA CATALYTIC SUBUNIT DNA metabolism protein#PC00009 DNA replication#P00017>Pol delta#P00533 CIOIN|Ensembl=ENSCING00000023119.1|UniProtKB=H2XTB8 H2XTB8 PTHR12758:SF19 APOPTOSIS INHIBITOR 5-RELATED APOPTOSIS INHIBITOR 5 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000004574.3|UniProtKB=F6XBT4 F6XBT4 PTHR10722:SF0 60S RIBOSOMAL PROTEIN L19 RIBOSOMAL PROTEIN L19 structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;structural molecule activity#GO:0005198;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic large ribosomal subunit#GO:0022625;large ribosomal subunit#GO:0015934;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;ribosomal subunit#GO:0044391 ribosomal protein#PC00202;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000018592.1|UniProtKB=H2XLB2 H2XLB2 PTHR10489:SF932 CELL ADHESION MOLECULE G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN cell adhesion molecule#PC00069 CIOIN|Ensembl=ENSCING00000021722.1|UniProtKB=H2XUX6 H2XUX6 PTHR31777:SF0 TRANSMEMBRANE PROTEIN 169 TRANSMEMBRANE PROTEIN 169 CIOIN|Ensembl=ENSCING00000016920.2|UniProtKB=F7B3V5 F7B3V5 LOC100182326 PTHR10209:SF881 OXIDOREDUCTASE, 2OG-FE II OXYGENASE FAMILY PROTEIN FI07970P-RELATED oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000007139.3|UniProtKB=F6S8Z0 F6S8Z0 PTHR10060:SF15 TATD FAMILY DEOXYRIBONUCLEASE DEOXYRIBONUCLEASE TATDN1 DNA metabolism protein#PC00009;endodeoxyribonuclease#PC00093 CIOIN|Ensembl=ENSCING00000023302.1|UniProtKB=H2XTA5 H2XTA5 PTHR10157:SF23 DOPAMINE BETA HYDROXYLASE RELATED MOXD1 HOMOLOG 1 hydroxylase#PC00122 CIOIN|Ensembl=ENSCING00000019536.1|UniProtKB=H2Y2P2 H2Y2P2 PTHR19143:SF327 FIBRINOGEN/TENASCIN/ANGIOPOEITIN FI21813P1-RELATED external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 CIOIN|Ensembl=ENSCING00000018721.1|UniProtKB=H2XRN4 H2XRN4 PTHR21567:SF87 CLASP CRESCERIN-LIKE PROTEIN CHE-12 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cellular process#GO:0009987;microtubule-based process#GO:0007017;organelle organization#GO:0006996 supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;cytoplasmic microtubule#GO:0005881;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622 non-motor microtubule binding protein#PC00166 CIOIN|Ensembl=ENSCING00000018858.1|UniProtKB=H2XQU6 H2XQU6 PTHR43143:SF1 METALLOPHOSPHOESTERASE, CALCINEURIN SUPERFAMILY SERINE_THREONINE-PROTEIN PHOSPHATASE CPPED1 protein phosphatase#PC00195;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000001048.3|UniProtKB=F6UNP2 F6UNP2 PTHR19918:SF1 CELL DIVISION CYCLE 20 CDC20 FIZZY -RELATED FIZZY-RELATED PROTEIN HOMOLOG protein-containing complex binding#GO:0044877;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;binding#GO:0005488 positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of protein metabolic process#GO:0051246;regulation of catabolic process#GO:0009894;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of proteasomal protein catabolic process#GO:1901800;protein catabolic process#GO:0030163;organonitrogen compound catabolic process#GO:1901565;regulation of protein catabolic process#GO:0042176;regulation of proteolysis involved in protein catabolic process#GO:1903050;positive regulation of proteolysis#GO:0045862;modification-dependent macromolecule catabolic process#GO:0043632;regulation of biological process#GO:0050789;positive regulation of metabolic process#GO:0009893;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;positive regulation of biological process#GO:0048518;proteolysis involved in protein catabolic process#GO:0051603;positive regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032436;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of proteolysis#GO:0030162;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;positive regulation of proteolysis involved in protein catabolic process#GO:1903052;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;organonitrogen compound metabolic process#GO:1901564;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of proteasomal protein catabolic process#GO:0061136;regulation of primary metabolic process#GO:0080090;positive regulation of protein metabolic process#GO:0051247;anaphase-promoting complex-dependent catabolic process#GO:0031145;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;positive regulation of catabolic process#GO:0009896;positive regulation of protein catabolic process#GO:0045732;regulation of metabolic process#GO:0019222;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434 ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;cullin-RING ubiquitin ligase complex#GO:0031461;transferase complex#GO:1990234;anaphase-promoting complex#GO:0005680;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;nuclear ubiquitin ligase complex#GO:0000152;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000004129.3|UniProtKB=F6V8N0 F6V8N0 LOC100177042 PTHR10696:SF25 GAMMA-BUTYROBETAINE HYDROXYLASE-RELATED OXIDOREDUCTASE AIM17-RELATED nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;cellular modified amino acid metabolic process#GO:0006575;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 hydroxylase#PC00122 CIOIN|Ensembl=ENSCING00000007334.3|UniProtKB=F6YJR3 F6YJR3 PTHR24332:SF9 HOMEOBOX PROTEIN CDX HOMEOTIC PROTEIN CAUDAL sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;animal organ development#GO:0048513;regulation of transcription by RNA polymerase II#GO:0006357;regionalization#GO:0003002;developmental process#GO:0032502;multicellular organism development#GO:0007275;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;embryo development#GO:0009790;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;anatomical structure morphogenesis#GO:0009653;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;animal organ morphogenesis#GO:0009887;anterior/posterior pattern specification#GO:0009952;multicellular organismal process#GO:0032501;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;pattern specification process#GO:0007389;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 CIOIN|Ensembl=ENSCING00000024091.1|UniProtKB=H2XYH7 H2XYH7 PTHR24246:SF27 OLFACTORY RECEPTOR AND ADENOSINE RECEPTOR ADENOSINE RECEPTOR, ISOFORM A G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711 CIOIN|Ensembl=ENSCING00000012307.2|UniProtKB=F6UMA7 F6UMA7 PTHR11232:SF47 PHOSPHOTYROSINE INTERACTION DOMAIN-CONTAINING FAMILY MEMBER PROTEIN DISABLED scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000017364.2|UniProtKB=F6X1D6 F6X1D6 PTHR13198:SF4 RING FINGER PROTEIN 25 E3 UBIQUITIN-PROTEIN LIGASE RNF25 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000002757|UniProtKB=Q4H3N8 Q4H3N8 ENY2 PTHR12514:SF1 ENHANCER OF YELLOW 2 TRANSCRIPTION FACTOR TRANSCRIPTION AND MRNA EXPORT FACTOR ENY2 molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;chromatin binding#GO:0003682;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;transcription coactivator activity#GO:0003713;protein-containing complex binding#GO:0044877 cellular localization#GO:0051641;macromolecule localization#GO:0033036;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;transport#GO:0006810;nucleic acid transport#GO:0050657;nitrogen compound transport#GO:0071705;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;RNA localization#GO:0006403;regulation of biological process#GO:0050789;organic substance transport#GO:0071702;establishment of localization#GO:0051234;regulation of biosynthetic process#GO:0009889;RNA transport#GO:0050658;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;nuclear transport#GO:0051169;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;poly(A)+ mRNA export from nucleus#GO:0016973;mRNA export from nucleus#GO:0006406;macromolecule biosynthetic process#GO:0009059;establishment of RNA localization#GO:0051236;regulation of DNA-templated transcription#GO:0006355;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;mRNA transport#GO:0051028;regulation of RNA metabolic process#GO:0051252;localization#GO:0051179;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;nuclear export#GO:0051168;regulation of macromolecule metabolic process#GO:0060255;nucleocytoplasmic transport#GO:0006913;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;nucleobase-containing compound transport#GO:0015931;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 SAGA-type complex#GO:0070461;peptidase complex#GO:1905368;histone acetyltransferase complex#GO:0000123;nucleus#GO:0005634;acetyltransferase complex#GO:1902493;intracellular membrane-bounded organelle#GO:0043231;protein-DNA complex#GO:0032993;catalytic complex#GO:1902494;chromatin#GO:0000785;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein acetyltransferase complex#GO:0031248;protein-containing complex#GO:0032991;chromosome#GO:0005694;SAGA complex#GO:0000124;membrane-bounded organelle#GO:0043227;DUBm complex#GO:0071819;nuclear protein-containing complex#GO:0140513 DNA-binding transcription factor#PC00218 CIOIN|Ensembl=ENSCING00000004364.3|UniProtKB=F6S5I8 F6S5I8 PTHR12603:SF0 CCR4-NOT TRANSCRIPTION COMPLEX RELATED CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 4 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 CCR4-NOT complex#GO:0030014;intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000018022.1|UniProtKB=H2XKJ8 H2XKJ8 LOC100181062 PTHR28457:SF2 COILED-COIL DOMAIN-CONTAINING PROTEIN 189 SIMILAR TO 4930578I06RIK PROTEIN CIOIN|Ensembl=ENSCING00000000042.3|UniProtKB=F6VUH2 F6VUH2 tmod PTHR10901:SF6 TROPOMODULIN TROPOMODULIN, ISOFORM N cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;binding#GO:0005488 cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 CIOIN|Ensembl=ENSCING00000007818.3|UniProtKB=F6XF93 F6XF93 PTHR47958:SF26 ATP-DEPENDENT RNA HELICASE DBP3 EUKARYOTIC INITIATION FACTOR 4A-III catalytic activity, acting on RNA#GO:0140098;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;helicase activity#GO:0004386;ATP-dependent activity#GO:0140657;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;catalytic activity, acting on a nucleic acid#GO:0140640;mRNA binding#GO:0003729 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;mRNA splicing, via spliceosome#GO:0000398;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;catalytic step 2 spliceosome#GO:0071013;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 RNA helicase#PC00032 CIOIN|Ensembl=ENSCING00000004389.3|UniProtKB=F7AUM2 F7AUM2 LOC100178049 PTHR13832:SF565 PROTEIN PHOSPHATASE 2C AT28366P-RELATED macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;dephosphorylation#GO:0016311;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein dephosphorylation#GO:0006470;cellular metabolic process#GO:0044237;cellular process#GO:0009987;protein metabolic process#GO:0019538;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 protein phosphatase#PC00195;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000011380.2|UniProtKB=F6R868 F6R868 LOC100179330 PTHR30289:SF8 UNCHARACTERIZED PROTEIN YBCL-RELATED YHYH DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000007251.3|UniProtKB=F6UW27 F6UW27 LOC100187186 PTHR31398:SF0 MEIOTIC NUCLEAR DIVISION PROTEIN 1 HOMOLOG MEIOTIC NUCLEAR DIVISION PROTEIN 1 HOMOLOG cellular aromatic compound metabolic process#GO:0006725;nuclear division#GO:0000280;cell cycle process#GO:0022402;nucleobase-containing compound metabolic process#GO:0006139;reciprocal homologous recombination#GO:0140527;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;meiotic cell cycle process#GO:1903046;meiosis I cell cycle process#GO:0061982;reciprocal meiotic recombination#GO:0007131;reproductive process#GO:0022414;meiosis I#GO:0007127;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;meiotic cell cycle#GO:0051321;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;reproduction#GO:0000003;organelle organization#GO:0006996;meiotic nuclear division#GO:0140013;sexual reproduction#GO:0019953;organelle fission#GO:0048285;cell cycle#GO:0007049;homologous recombination#GO:0035825;DNA metabolic process#GO:0006259 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000010888.3|UniProtKB=F7AGZ7 F7AGZ7 LOC100186187 PTHR24006:SF915 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE-RELATED cysteine-type peptidase activity#GO:0008234;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;cysteine-type deubiquitinase activity#GO:0004843 protein modification by small protein conjugation or removal#GO:0070647;mitotic cell cycle phase transition#GO:0044772;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cell cycle G1/S phase transition#GO:0044843;cell cycle process#GO:0022402;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular process#GO:0009987;post-translational protein modification#GO:0043687;mitotic cell cycle process#GO:1903047;cell cycle phase transition#GO:0044770;primary metabolic process#GO:0044238;G1/S transition of mitotic cell cycle#GO:0000082;mitotic cell cycle#GO:0000278;nitrogen compound metabolic process#GO:0006807;protein modification by small protein removal#GO:0070646;protein deubiquitination#GO:0016579;cell cycle#GO:0007049;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cysteine protease#PC00081;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000006787.3|UniProtKB=F6VDC4 F6VDC4 PTHR10465:SF3 TRANSMEMBRANE GTPASE FZO1 TRANSMEMBRANE GTPASE MARF-RELATED GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824 localization#GO:0051179;mitochondrial fusion#GO:0008053;cellular component organization or biogenesis#GO:0071840;organelle localization#GO:0051640;organelle organization#GO:0006996;cellular component organization#GO:0016043;mitochondrion organization#GO:0007005;cellular process#GO:0009987;organelle fusion#GO:0048284 envelope#GO:0031975;bounding membrane of organelle#GO:0098588;mitochondrial membrane#GO:0031966;intracellular membrane-bounded organelle#GO:0043231;mitochondrial outer membrane#GO:0005741;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867 CIOIN|Ensembl=ENSCING00000005036.3|UniProtKB=F6T9S9 F6T9S9 myc PTHR45851:SF3 MYC PROTO-ONCOGENE MYC PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 basic helix-loop-helix transcription factor#PC00055 p53 pathway feedback loops 2#P04398>Myc#P04649;Wnt signaling pathway#P00057>Wnt Target Genes#G01558;Oxidative stress response#P00046>Myc#P01124;PDGF signaling pathway#P00047>c-Myc#P01172 CIOIN|Ensembl=ENSCING00000018097.1|UniProtKB=H2XRS9 H2XRS9 PTHR12498:SF0 N-TERMINAL ASPARAGINE AMIDOHYDROLASE PROTEIN N-TERMINAL ASPARAGINE AMIDOHYDROLASE hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000006210.3|UniProtKB=F6X0L7 F6X0L7 PTHR12083:SF9 BIFUNCTIONAL POLYNUCLEOTIDE PHOSPHATASE/KINASE BIFUNCTIONAL POLYNUCLEOTIDE PHOSPHATASE_KINASE hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;nucleic acid binding#GO:0003676;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;hydrolase activity#GO:0016787;transferase activity, transferring phosphorus-containing groups#GO:0016772;double-stranded DNA binding#GO:0003690;kinase activity#GO:0016301;phosphoric ester hydrolase activity#GO:0042578 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;DNA damage response#GO:0006974;response to stress#GO:0006950;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular response to stress#GO:0033554;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 nucleotide phosphatase#PC00173 CIOIN|Ensembl=ENSCING00000007350.3|UniProtKB=F6V5G2 F6V5G2 PTHR24115:SF421 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF25 pyrophosphatase activity#GO:0016462;cytoskeletal protein binding#GO:0008092;microtubule motor activity#GO:0003777;tubulin binding#GO:0015631;ATP-dependent activity#GO:0140657;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;cytoskeletal motor activity#GO:0003774;microtubule binding#GO:0008017;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;ribonucleoside triphosphate phosphatase activity#GO:0017111;ATP hydrolysis activity#GO:0016887 microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;microtubule associated complex#GO:0005875;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 CIOIN|Ensembl=ENSCING00000011367.2|UniProtKB=F6U8M8 F6U8M8 LOC100178975 PTHR10476:SF4 CHARGED MULTIVESICULAR BODY PROTEIN CHARGED MULTIVESICULAR BODY PROTEIN 2A endosomal transport#GO:0016197;cellular localization#GO:0051641;macromolecule localization#GO:0033036;vacuolar transport#GO:0007034;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;late endosome to vacuole transport#GO:0045324;cellular process#GO:0009987;multivesicular body sorting pathway#GO:0071985;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;endosome transport via multivesicular body sorting pathway#GO:0032509;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endosome membrane#GO:0010008;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle membrane#GO:0030659;late endosome#GO:0005770 membrane traffic protein#PC00150 CIOIN|Ensembl=ENSCING00000004349.3|UniProtKB=F6TN58 F6TN58 LOC100185119 PTHR36978:SF4 P-LOOP CONTAINING NUCLEOTIDE TRIPHOSPHATE HYDROLASE P-LOOP CONTAINING NUCLEOSIDE TRIPHOSPHATE HYDROLASE PROTEIN metabolite interconversion enzyme#PC00262;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000003527.3|UniProtKB=F7AZA6 F7AZA6 LOC100179436 PTHR19991:SF2 L 2 01289 GH08893P CIOIN|Ensembl=ENSCING00000024656.1|UniProtKB=H2XYF8 H2XYF8 LOC100176189 PTHR45877:SF2 E3 UBIQUITIN-PROTEIN LIGASE SIAH2 E3 UBIQUITIN-PROTEIN LIGASE SINA-RELATED ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 Wnt signaling pathway#P00057>SIAH-1#P01433 CIOIN|Ensembl=ENSCING00000014970.2|UniProtKB=F6UW62 F6UW62 PTHR23282:SF146 APICAL ENDOSOMAL GLYCOPROTEIN PRECURSOR. RT07201P-RELATED CIOIN|Ensembl=ENSCING00000009756.3|UniProtKB=F6ZBF1 F6ZBF1 LOC100178245 PTHR43344:SF2 PHOSPHOSERINE PHOSPHATASE PHOSPHOSERINE PHOSPHATASE cation binding#GO:0043169;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;magnesium ion binding#GO:0000287;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;metal ion binding#GO:0046872;ion binding#GO:0043167;phosphoric ester hydrolase activity#GO:0042578 organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;proteinogenic amino acid metabolic process#GO:0170039;proteinogenic amino acid biosynthetic process#GO:0170038;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;phosphorus metabolic process#GO:0006793;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;alpha-amino acid biosynthetic process#GO:1901607;nitrogen compound metabolic process#GO:0006807;dephosphorylation#GO:0016311;amino acid biosynthetic process#GO:0008652;alpha-amino acid metabolic process#GO:1901605;small molecule biosynthetic process#GO:0044283;L-amino acid biosynthetic process#GO:0170034;carboxylic acid metabolic process#GO:0019752;L-amino acid metabolic process#GO:0170033;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 phosphatase#PC00181;hydrolase#PC00121 Serine glycine biosynthesis#P02776>Phosphoserine phosphatase#P03159 CIOIN|Ensembl=ENSCING00000002192.3|UniProtKB=F6S566 F6S566 PTHR24230:SF0 G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;neuropeptide signaling pathway#GO:0007218;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 CIOIN|Ensembl=ENSCING00000021614.1|UniProtKB=H2Y1F0 H2Y1F0 PTHR20766:SF3 LARGE NEUTRAL AMINO ACIDS TRANSPORTER SMALL SUBUNIT 4-LIKE ISOFORM X1 LARGE NEUTRAL AMINO ACIDS TRANSPORTER SMALL SUBUNIT 4-LIKE ISOFORM X1 transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;organic acid transmembrane transporter activity#GO:0005342;L-amino acid transmembrane transporter activity#GO:0015179;organic anion transmembrane transporter activity#GO:0008514;amino acid transmembrane transporter activity#GO:0015171;neutral L-amino acid transmembrane transporter activity#GO:0015175;transporter activity#GO:0005215 localization#GO:0051179;neutral amino acid transport#GO:0015804;organic substance transport#GO:0071702;establishment of localization#GO:0051234;amino acid transport#GO:0006865;organic anion transport#GO:0015711;organic acid transport#GO:0015849;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942 CIOIN|Ensembl=ENSCING00000009382.3|UniProtKB=F6WBK6 F6WBK6 PTHR44186:SF1 FAMILY NOT NAMED BARDET-BIEDL SYNDROME 4 PROTEIN CIOIN|Ensembl=ENSCING00000006870.3|UniProtKB=F6ZXD5 F6ZXD5 LOC100186124 PTHR12385:SF12 CHOLINE TRANSPORTER-LIKE (SLC FAMILY 44) CHOLINE TRANSPORTER-LIKE PROTEIN transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 localization#GO:0051179;establishment of localization#GO:0051234;cellular process#GO:0009987;transmembrane transport#GO:0055085;transport#GO:0006810 cellular anatomical entity#GO:0110165;membrane#GO:0016020 secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000006248.3|UniProtKB=F6XNV2 F6XNV2 LOC100177271 PTHR42904:SF6 NUDIX HYDROLASE, NUDC SUBFAMILY NAD-CAPPED RNA HYDROLASE NUDT12 pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;heterocycle catabolic process#GO:0046700;organonitrogen compound catabolic process#GO:1901565;pyridine nucleotide metabolic process#GO:0019362;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;cellular nitrogen compound catabolic process#GO:0044270;phosphate-containing compound metabolic process#GO:0006796;purine-containing compound catabolic process#GO:0072523;organic cyclic compound metabolic process#GO:1901360;purine nucleotide catabolic process#GO:0006195;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;pyridine-containing compound metabolic process#GO:0072524;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;NADP metabolic process#GO:0006739;purine nucleotide metabolic process#GO:0006163;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;nucleoside phosphate catabolic process#GO:1901292;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;nucleotide catabolic process#GO:0009166;nicotinamide nucleotide metabolic process#GO:0046496;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organophosphate catabolic process#GO:0046434;primary metabolic process#GO:0044238;aromatic compound catabolic process#GO:0019439;organic cyclic compound catabolic process#GO:1901361;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;nucleotide metabolic process#GO:0009117;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000002896.3|UniProtKB=F6SZL1 F6SZL1 PTHR47572:SF4 LIPOPROTEIN-RELATED LACTONASE DRP35 CIOIN|Ensembl=ENSCING00000008352.3|UniProtKB=F7B3M4 F7B3M4 LOC100181913 PTHR10263:SF18 V-TYPE PROTON ATPASE PROTEOLIPID SUBUNIT V-TYPE PROTON ATPASE 21 KDA PROTEOLIPID SUBUNIT C'' cellular anatomical entity#GO:0110165;membrane#GO:0016020 ATP synthase#PC00002;primary active transporter#PC00068;transporter#PC00227 CIOIN|Ensembl=ENSCING00000019587.1|UniProtKB=H2XV30 H2XV30 LOC100186296 PTHR22776:SF97 MARVEL-CONTAINING POTENTIAL LIPID RAFT-ASSOCIATED PROTEIN RE01453P cellular anatomical entity#GO:0110165;membrane#GO:0016020 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000024731.1|UniProtKB=F7BDE0 F7BDE0 PTHR12805:SF0 KIN17 KIN, ANTIGENIC DETERMINANT OF RECA PROTEIN HOMOLOG DNA_RNA-BINDING PROTEIN KIN17 nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;response to stress#GO:0006950;nitrogen compound metabolic process#GO:0006807;DNA replication#GO:0006260;cellular response to stress#GO:0033554;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000013213.1|UniProtKB=F6ZZB6 F6ZZB6 PTHR34404:SF3 REGULATORY PROTEIN, FMDB FAMILY REGULATORY PROTEIN, FMDB FAMILY CIOIN|Ensembl=ENSCING00000002018.3|UniProtKB=F6W6K0 F6W6K0 PTHR18934:SF237 ATP-DEPENDENT RNA HELICASE ATP-DEPENDENT DNA_RNA HELICASE DHX36 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;helicase activity#GO:0004386;ATP-dependent activity#GO:0140657;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;catalytic activity, acting on a nucleic acid#GO:0140640 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA helicase#PC00032 CIOIN|Ensembl=ENSCING00000002092.3|UniProtKB=F7AA18 F7AA18 LOC100187335 PTHR13131:SF5 CYSTINOSIN CYSTINOSIN L-amino acid transmembrane transporter activity#GO:0015179;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;amino acid transmembrane transporter activity#GO:0015171;organic anion transmembrane transporter activity#GO:0008514;organic acid transmembrane transporter activity#GO:0005342;transporter activity#GO:0005215 localization#GO:0051179;neutral amino acid transport#GO:0015804;organic substance transport#GO:0071702;L-amino acid transport#GO:0015807;establishment of localization#GO:0051234;organic anion transport#GO:0015711;amino acid transport#GO:0006865;organic acid transport#GO:0015849;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942 bounding membrane of organelle#GO:0098588;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;vacuolar membrane#GO:0005774;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 amino acid transporter#PC00046;transporter#PC00227 CIOIN|Ensembl=ENSCING00000018235.1|UniProtKB=Q1RL72 Q1RL72 Ci-ZF(ZZ)-2 PTHR24202:SF53 E3 UBIQUITIN-PROTEIN LIGASE MIB2 E3 UBIQUITIN-PROTEIN LIGASE MIB1 protein ubiquitination#GO:0016567;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;transport#GO:0006810;endocytosis#GO:0006897;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;vesicle-mediated transport#GO:0016192;cell communication#GO:0007154;cellular process#GO:0009987;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;localization#GO:0051179;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;import into cell#GO:0098657;signaling#GO:0023052;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;Notch signaling pathway#GO:0007219 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000022358.1|UniProtKB=H2XTB0 H2XTB0 PTHR11489:SF9 40S RIBOSOMAL PROTEIN SA SMALL RIBOSOMAL SUBUNIT PROTEIN US2 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 cellular component biogenesis#GO:0044085;peptide metabolic process#GO:0006518;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;translation#GO:0006412;protein-RNA complex assembly#GO:0022618;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;ribosome biogenesis#GO:0042254;non-membrane-bounded organelle assembly#GO:0140694;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular component assembly#GO:0022607;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;peptide biosynthetic process#GO:0043043;protein-containing complex organization#GO:0043933;organelle organization#GO:0006996;ribonucleoprotein complex biogenesis#GO:0022613;protein-RNA complex organization#GO:0071826;ribosomal small subunit biogenesis#GO:0042274 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic small ribosomal subunit#GO:0022627;cytosol#GO:0005829;small ribosomal subunit#GO:0015935;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000003135.3|UniProtKB=F6RCD1 F6RCD1 PTHR20913:SF7 TBC1 DOMAIN FAMILY MEMBER 20/GTPASE RE60063P nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 localization#GO:0051179;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;establishment of localization#GO:0051234;transport#GO:0006810;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 GTPase-activating protein#PC00257 CIOIN|Ensembl=ENSCING00000006571.3|UniProtKB=F6R1E8 F6R1E8 LOC100184343 PTHR14002:SF54 ENDOGLIN/TGF-BETA RECEPTOR TYPE III ZONA PELLUCIDA SPERM-BINDING PROTEIN 2 transmembrane signal receptor#PC00197 CIOIN|Ensembl=ENSCING00000023459.1|UniProtKB=A0A1W2WQT6 A0A1W2WQT6 zf(cchc)-24 PTHR23147:SF288 SERINE/ARGININE RICH SPLICING FACTOR SERINE_ARGININE-RICH SPLICING FACTOR 7 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;nuclear speck#GO:0016607;organelle#GO:0043226;nuclear body#GO:0016604;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA splicing factor#PC00148;RNA processing factor#PC00147;RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000002793.3|UniProtKB=F6XMX2 F6XMX2 PTHR10870:SF0 CELL CYCLE CHECKPOINT PROTEIN RAD1 CELL CYCLE CHECKPOINT PROTEIN RAD1 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;DNA damage checkpoint signaling#GO:0000077;negative regulation of cell cycle process#GO:0010948;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;cell cycle checkpoint signaling#GO:0000075;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;signal transduction in response to DNA damage#GO:0042770;intracellular signal transduction#GO:0035556;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;negative regulation of cell cycle#GO:0045786;macromolecule metabolic process#GO:0043170;negative regulation of cell cycle phase transition#GO:1901988;regulation of cell cycle phase transition#GO:1901987;cellular metabolic process#GO:0044237;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;regulation of cell cycle process#GO:0010564;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;DNA integrity checkpoint signaling#GO:0031570;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;condensed chromosome#GO:0000793;intracellular organelle lumen#GO:0070013;condensed nuclear chromosome#GO:0000794;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 DNA metabolism protein#PC00009;exodeoxyribonuclease#PC00098 CIOIN|Ensembl=ENSCING00000021049.1|UniProtKB=H2XNE8 H2XNE8 PTHR18945:SF916 NEUROTRANSMITTER GATED ION CHANNEL GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT BETA-LIKE inorganic molecular entity transmembrane transporter activity#GO:0015318;signaling receptor activity#GO:0038023;chloride channel activity#GO:0005254;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;molecular transducer activity#GO:0060089;chloride transmembrane transporter activity#GO:0015108;monoatomic anion transmembrane transporter activity#GO:0008509;inorganic anion transmembrane transporter activity#GO:0015103;transporter activity#GO:0005215;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267;transmembrane signaling receptor activity#GO:0004888 ligand-gated ion channel#PC00141;ion channel#PC00133;transporter#PC00227 CIOIN|Ensembl=ENSCING00000012927.2|UniProtKB=F6RLZ7 F6RLZ7 zf(c2h2)-41 PTHR24406:SF8 TRANSCRIPTIONAL REPRESSOR CTCFL-RELATED FI01110P-RELATED nucleic acid binding#GO:0003676;protein-containing complex binding#GO:0044877;chromatin DNA binding#GO:0031490;binding#GO:0005488;organic cyclic compound binding#GO:0097159;chromatin binding#GO:0003682;DNA binding#GO:0003677 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;chromosome#GO:0005694;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 CIOIN|Ensembl=ENSCING00000011973.2|UniProtKB=F6RYD4 F6RYD4 LOC100186228 PTHR33447:SF2 GLUTATHIONE GAMMA-GLUTAMYLCYSTEINYLTRANSFERASE GLUTATHIONE GAMMA-GLUTAMYLCYSTEINYLTRANSFERASE transferase activity#GO:0016740;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824 cellular response to stimulus#GO:0051716;secondary metabolic process#GO:0019748;cellular response to chemical stimulus#GO:0070887;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;amide biosynthetic process#GO:0043604;response to stimulus#GO:0050896;detoxification#GO:0098754;peptide biosynthetic process#GO:0043043;response to stress#GO:0006950;secondary metabolite biosynthetic process#GO:0044550;response to chemical#GO:0042221;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;response to toxic substance#GO:0009636;amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 CIOIN|Ensembl=ENSCING00000006994.3|UniProtKB=F6SAX1 F6SAX1 PTHR21431:SF0 PREFOLDIN SUBUNIT 6 PREFOLDIN SUBUNIT 6 protein binding#GO:0005515;protein-folding chaperone binding#GO:0051087;binding#GO:0005488 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein-containing complex assembly#GO:0065003;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;chaperone-mediated protein complex assembly#GO:0051131;cellular component organization#GO:0016043;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nitrogen compound metabolic process#GO:0006807;protein-containing complex organization#GO:0043933;protein folding#GO:0006457;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000006340.3|UniProtKB=F6PRZ9 F6PRZ9 PTHR12616:SF8 VACUOLAR PROTEIN SORTING VPS41 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 8 HOMOLOG vesicle fusion#GO:0006906;cellular localization#GO:0051641;macromolecule localization#GO:0033036;protein targeting to vacuole#GO:0006623;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;transport#GO:0006810;nitrogen compound transport#GO:0071705;establishment of protein localization#GO:0045184;organic substance transport#GO:0071702;establishment of localization#GO:0051234;vesicle organization#GO:0016050;protein localization to organelle#GO:0033365;organelle fusion#GO:0048284;establishment of protein localization to vacuole#GO:0072666;vacuolar transport#GO:0007034;protein localization to vacuole#GO:0072665;protein targeting#GO:0006605;establishment of protein localization to organelle#GO:0072594;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;membrane fusion#GO:0061025;cellular macromolecule localization#GO:0070727;organelle organization#GO:0006996;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 membrane protein complex#GO:0098796;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle tethering complex#GO:0099023;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;late endosome#GO:0005770 membrane traffic protein#PC00150 CIOIN|Ensembl=ENSCING00000013303.2|UniProtKB=L7N0T0 L7N0T0 PTHR23138:SF87 RAN BINDING PROTEIN E3 SUMO-PROTEIN LIGASE RANBP2 nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 envelope#GO:0031975;cytoplasm#GO:0005737;nuclear pore#GO:0005643;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear envelope#GO:0005635;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000006122.3|UniProtKB=F6VSC2 F6VSC2 PTHR11616:SF325 SODIUM/CHLORIDE DEPENDENT TRANSPORTER TRANSPORTER secondary active monocarboxylate transmembrane transporter activity#GO:0015355;inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;organic acid:sodium symporter activity#GO:0005343;organic acid transmembrane transporter activity#GO:0005342;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;chloride transmembrane transporter activity#GO:0015108;organic anion transmembrane transporter activity#GO:0008514;monoatomic cation transmembrane transporter activity#GO:0008324;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;amino acid:sodium symporter activity#GO:0005283;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;metal ion transmembrane transporter activity#GO:0046873;active monoatomic ion transmembrane transporter activity#GO:0022853;monoatomic anion transmembrane transporter activity#GO:0008509;monocarboxylic acid transmembrane transporter activity#GO:0008028;amino acid transmembrane transporter activity#GO:0015171;inorganic anion transmembrane transporter activity#GO:0015103;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;organic anion transport#GO:0015711;amino acid transport#GO:0006865;organic acid transport#GO:0015849;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;localization#GO:0051179;organic substance transport#GO:0071702;sodium ion transport#GO:0006814;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;sodium ion transmembrane transport#GO:0035725 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 primary active transporter#PC00068;transporter#PC00227 CIOIN|Ensembl=ENSCING00000021118.1|UniProtKB=H2Y3Q9 H2Y3Q9 LOC100185957 PTHR22576:SF37 MUCOSA ASSOCIATED LYMPHOID TISSUE LYMPHOMA TRANSLOCATION PROTEIN 1/PARACASPASE MUCOSA-ASSOCIATED LYMPHOID TISSUE LYMPHOMA TRANSLOCATION PROTEIN 1 cysteine protease#PC00081;protease#PC00190 CIOIN|Ensembl=ENSCING00000019770.1|UniProtKB=H2Y3K7 H2Y3K7 PTHR19143:SF458 FIBRINOGEN/TENASCIN/ANGIOPOEITIN FIBRINOGEN C-TERMINAL DOMAIN-CONTAINING PROTEIN-RELATED external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 CIOIN|Ensembl=ENSCING00000009600.3|UniProtKB=F7AWW1 F7AWW1 LOC100184992 PTHR21230:SF1 VESICLE TRANSPORT V-SNARE PROTEIN VTI1-RELATED GOLGI SNAP RECEPTOR COMPLEX MEMBER 2 molecular adaptor activity#GO:0060090;protein binding#GO:0005515;SNAP receptor activity#GO:0005484;binding#GO:0005488;SNARE binding#GO:0000149;protein-macromolecule adaptor activity#GO:0030674 localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;vesicle fusion#GO:0006906;membrane fusion#GO:0061025;establishment of localization#GO:0051234;membrane organization#GO:0061024;organelle organization#GO:0006996;organelle membrane fusion#GO:0090174;transport#GO:0006810;vesicle-mediated transport#GO:0016192;vesicle organization#GO:0016050;cellular component organization#GO:0016043;cellular process#GO:0009987;organelle fusion#GO:0048284 bounding membrane of organelle#GO:0098588;endosome#GO:0005768;COPII-coated ER to Golgi transport vesicle#GO:0030134;intracellular membrane-bounded organelle#GO:0043231;SNARE complex#GO:0031201;late endosome membrane#GO:0031902;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endosome membrane#GO:0010008;vesicle#GO:0031982;intracellular organelle#GO:0043229;transport vesicle membrane#GO:0030658;endoplasmic reticulum subcompartment#GO:0098827;cytoplasmic vesicle membrane#GO:0030659;late endosome#GO:0005770;membrane protein complex#GO:0098796;ER to Golgi transport vesicle membrane#GO:0012507;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;membrane#GO:0016020;coated vesicle#GO:0030135;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;coated vesicle membrane#GO:0030662;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;transport vesicle#GO:0030133;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 SNARE protein#PC00034 CIOIN|Ensembl=ENSCING00000013406.2|UniProtKB=F6VR76 F6VR76 PTHR35169:SF1 FE2OG DIOXYGENASE DOMAIN-CONTAINING PROTEIN PROLYL 4-HYDROXYLASE ALPHA SUBUNIT FE(2+) 2OG DIOXYGENASE DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000008258.3|UniProtKB=F6QZ03 F6QZ03 PTHR22811:SF14 TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN LP01981P-RELATED endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;Golgi organization#GO:0007030;macromolecule localization#GO:0033036;transport#GO:0006810;endomembrane system organization#GO:0010256;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;organelle organization#GO:0006996;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 COPII-coated ER to Golgi transport vesicle#GO:0030134;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;cellular anatomical entity#GO:0110165;organelle#GO:0043226;coated vesicle#GO:0030135;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;endoplasmic reticulum#GO:0005783;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793 vesicle coat protein#PC00235 CIOIN|Ensembl=ENSCING00000022131.1|UniProtKB=H2XK44 H2XK44 LOC100186713 PTHR22812:SF112 CHROMOBOX PROTEIN CHROMATOR, ISOFORM A-RELATED protein binding#GO:0005515;protein-containing complex binding#GO:0044877;methylated histone binding#GO:0035064;histone binding#GO:0042393;binding#GO:0005488;chromatin binding#GO:0003682;modification-dependent protein binding#GO:0140030 negative regulation of gene expression#GO:0010629;negative regulation of cellular metabolic process#GO:0031324;protein-DNA complex organization#GO:0071824;negative regulation of biological process#GO:0048519;negative regulation of biosynthetic process#GO:0009890;heterochromatin formation#GO:0031507;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;negative regulation of gene expression, epigenetic#GO:0045814;cellular process#GO:0009987;epigenetic regulation of gene expression#GO:0040029;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;negative regulation of macromolecule biosynthetic process#GO:0010558;heterochromatin organization#GO:0070828;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;protein-containing complex organization#GO:0043933;regulation of cellular process#GO:0050794;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;chromatin remodeling#GO:0006338;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromatin#GO:0000785;protein-DNA complex#GO:0032993;chromosome#GO:0005694;chromosome, centromeric region#GO:0000775;chromosomal region#GO:0098687;heterochromatin#GO:0000792;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000004680.3|UniProtKB=F6RBI7 F6RBI7 LOC100186176 PTHR12129:SF15 HEPARAN SULFATE 2-O-SULFOTRANSFERASE URONYL 2-SULFOTRANSFERASE transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000003905.3|UniProtKB=F6T9L2 F6T9L2 LOC100175529 PTHR46079:SF2 FERM DOMAIN-CONTAINING PROTEIN 4 FERM DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000004415.3|UniProtKB=F6YNP9 F6YNP9 PTHR10157:SF23 DOPAMINE BETA HYDROXYLASE RELATED MOXD1 HOMOLOG 1 hydroxylase#PC00122 CIOIN|Ensembl=ENSCING00000000684.3|UniProtKB=F6QRX3 F6QRX3 LOC100175706 PTHR12782:SF5 MICROSOMAL PROSTAGLANDIN E SYNTHASE-2 PROSTAGLANDIN E SYNTHASE 2 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 reductase#PC00198;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000003946.3|UniProtKB=Q4H3J8 Q4H3J8 Ci-Fhl1_2_3 PTHR24205:SF4 FOUR AND A HALF LIM DOMAINS PROTEIN PROTEIN ESPINAS molecular adaptor activity#GO:0060090;transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;protein-macromolecule adaptor activity#GO:0030674 supramolecular complex#GO:0099080;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;Z disc#GO:0030018;cellular anatomical entity#GO:0110165;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;contractile fiber#GO:0043292;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;sarcomere#GO:0030017;membrane-bounded organelle#GO:0043227;myofibril#GO:0030016;I band#GO:0031674 transcription cofactor#PC00217 CIOIN|Ensembl=ENSCING00000004593.3|UniProtKB=F6WPT0 F6WPT0 ftzf PTHR24086:SF15 NUCLEAR RECEPTOR SUBFAMILY 5 GROUP A NUCLEAR HORMONE RECEPTOR FTZ-F1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690 signal transduction#GO:0007165;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;hormone-mediated signaling pathway#GO:0009755;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;cellular response to hormone stimulus#GO:0032870;regulation of biosynthetic process#GO:0009889;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;signaling#GO:0023052;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;regulation of DNA-templated transcription#GO:0006355;cell communication#GO:0007154;cellular process#GO:0009987;tissue development#GO:0009888;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;response to hormone#GO:0009725;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;response to chemical#GO:0042221;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C4 zinc finger nuclear receptor#PC00169;zinc finger transcription factor#PC00244 CIOIN|Ensembl=ENSCING00000008070.3|UniProtKB=F6ZPU3 F6ZPU3 LOC100179545 PTHR20902:SF0 41-2 PROTEIN ANTIGEN-RELATED TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 5 localization#GO:0051179;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;establishment of localization#GO:0051234;transport#GO:0006810;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193 endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle tethering complex#GO:0099023;TRAPP complex#GO:0030008;Golgi apparatus#GO:0005794;intracellular protein-containing complex#GO:0140535;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793 CIOIN|Ensembl=ENSCING00000007598.4|UniProtKB=F6ZJZ6 F6ZJZ6 PTHR12609:SF0 MICROTUBULE ASSOCIATED PROTEIN XMAP215 CYTOSKELETON-ASSOCIATED PROTEIN 5 cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;transferase activity#GO:0016740;binding#GO:0005488;catalytic activity#GO:0003824;protein binding#GO:0005515;microtubule binding#GO:0008017;catalytic activity, acting on a protein#GO:0140096 establishment or maintenance of cell polarity#GO:0007163;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;mitotic spindle organization#GO:0007052;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;centrosome cycle#GO:0007098;protein-containing complex assembly#GO:0065003;centrosome duplication#GO:0051298;cellular component organization#GO:0016043;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cellular process#GO:0009987;microtubule polymerization or depolymerization#GO:0031109;microtubule organizing center organization#GO:0031023;mitotic cell cycle process#GO:1903047;cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;microtubule polymerization#GO:0046785;microtubule-based process#GO:0007017;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;supramolecular fiber organization#GO:0097435;protein polymerization#GO:0051258;cell cycle#GO:0007049;cytoskeleton organization#GO:0007010;spindle organization#GO:0007051 supramolecular complex#GO:0099080;spindle pole#GO:0000922;microtubule organizing center#GO:0005815;kinetochore#GO:0000776;condensed chromosome, centromeric region#GO:0000779;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;centrosome#GO:0005813;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;chromosome#GO:0005694;microtubule cytoskeleton#GO:0015630;chromosomal region#GO:0098687;cytoskeleton#GO:0005856;microtubule plus-end#GO:0035371;spindle#GO:0005819;microtubule#GO:0005874 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 CIOIN|Ensembl=ENSCING00000014528.2|UniProtKB=F6VN69 F6VN69 PTHR11360:SF284 MONOCARBOXYLATE TRANSPORTER EG:103B4.3 PROTEIN-RELATED transporter#PC00227 CIOIN|Ensembl=ENSCING00000009876.3|UniProtKB=F6XFA2 F6XFA2 LOC778910 PTHR24118:SF99 POTE ANKYRIN DOMAIN POTE ANKYRIN DOMAIN FAMILY MEMBER 3C-RELATED membrane traffic protein#PC00150 CIOIN|Ensembl=ENSCING00000004488.3|UniProtKB=F6TFD0 F6TFD0 LOC100186285 PTHR19842:SF0 G BETA-LIKE PROTEIN GBL TARGET OF RAPAMYCIN COMPLEX SUBUNIT LST8 signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of organelle organization#GO:0033043;regulation of cellular component organization#GO:0051128;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cytoskeleton organization#GO:0051493;regulation of cellular process#GO:0050794;regulation of actin cytoskeleton organization#GO:0032956;biological regulation#GO:0065007;regulation of actin filament-based process#GO:0032970;intracellular signal transduction#GO:0035556;signaling#GO:0023052;TOR signaling#GO:0031929 intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991 CIOIN|Ensembl=ENSCING00000011722.2|UniProtKB=F6W067 F6W067 PTHR13806:SF46 FLOTILLIN-RELATED FLOTILLIN-1-RELATED enzyme binding#GO:0019899;protein binding#GO:0005515;protease binding#GO:0002020;binding#GO:0005488 localization#GO:0051179;protein localization to plasma membrane#GO:0072659;protein localization to cell periphery#GO:1990778;localization within membrane#GO:0051668;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;protein localization to membrane#GO:0072657;cellular process#GO:0009987;protein localization#GO:0008104 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 CIOIN|Ensembl=ENSCING00000005535.3|UniProtKB=F6Y3M3 F6Y3M3 LOC100177468 PTHR28631:SF1 UPF0692 PROTEIN C19ORF54 ACTIN MATURATION PROTEASE CIOIN|Ensembl=ENSCING00000000852.3|UniProtKB=F6R0P0 F6R0P0 PTHR11700:SF8 30S RIBOSOMAL PROTEIN S10 FAMILY MEMBER 40S RIBOSOMAL PROTEIN S20 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic small ribosomal subunit#GO:0022627;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;small ribosomal subunit#GO:0015935;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000009877.3|UniProtKB=H2XRG1 H2XRG1 PTHR24096:SF149 LONG-CHAIN-FATTY-ACID--COA LIGASE AMP-BINDING DOMAIN-CONTAINING PROTEIN-RELATED ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877 metabolite interconversion enzyme#PC00262;ligase#PC00142 CIOIN|Ensembl=ENSCING00000016482.2|UniProtKB=F6ZGS5 F6ZGS5 LOC100176772 PTHR19370:SF185 NADH-CYTOCHROME B5 REDUCTASE NADH-CYTOCHROME B5 REDUCTASE nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;flavin adenine dinucleotide binding#GO:0050660;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;anion binding#GO:0043168 reductase#PC00198;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000013860.2|UniProtKB=F6QG73 F6QG73 PTHR12776:SF1 KAZRIN-RELATED KAZRIN CIOIN|Ensembl=ENSCING00000004130.3|UniProtKB=F6ZN60 F6ZN60 LOC100177730 PTHR12431:SF14 SORTING NEXIN 17 AND 27 LD15323P lipid binding#GO:0008289;phosphatidylinositol binding#GO:0035091;phospholipid binding#GO:0005543;binding#GO:0005488 endosomal transport#GO:0016197;localization within membrane#GO:0051668;cellular localization#GO:0051641;vesicle-mediated transport to the plasma membrane#GO:0098876;macromolecule localization#GO:0033036;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;organic substance transport#GO:0071702;endocytic recycling#GO:0032456;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 cytoplasm#GO:0005737;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular vesicle#GO:0097708;early endosome#GO:0005769;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000002884.3|UniProtKB=F6SZY0 F6SZY0 PTHR10631:SF3 N 2 ,N 2 -DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE TRNA (GUANINE(26)-N(2))-DIMETHYLTRANSFERASE cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA modification#GO:0009451;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;tRNA modification#GO:0006400;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;macromolecule methylation#GO:0043414;tRNA methylation#GO:0030488;organic cyclic compound metabolic process#GO:1901360;methylation#GO:0032259;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;RNA methylation#GO:0001510;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 RNA metabolism protein#PC00031;RNA methyltransferase#PC00033 CIOIN|Ensembl=ENSCING00000007077.3|UniProtKB=F6WVW2 F6WVW2 PTHR10075:SF100 BASIGIN RELATED FASCICLIN-2 cell adhesion molecule binding#GO:0050839;cell-cell adhesion mediator activity#GO:0098632;protein binding#GO:0005515;binding#GO:0005488 neuron projection guidance#GO:0097485;cell recognition#GO:0008037;neurogenesis#GO:0022008;cell projection organization#GO:0030030;developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cellular anatomical entity morphogenesis#GO:0032989;system development#GO:0048731;cell differentiation#GO:0030154;axon guidance#GO:0007411;anatomical structure morphogenesis#GO:0009653;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;axonogenesis#GO:0007409;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;homophilic cell adhesion via plasma membrane adhesion molecules#GO:0007156;cell-cell adhesion via plasma-membrane adhesion molecules#GO:0098742;cell-cell adhesion#GO:0098609;cellular component organization#GO:0016043;cell adhesion#GO:0007155;cell morphogenesis#GO:0000902;cellular process#GO:0009987;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;cell morphogenesis involved in neuron differentiation#GO:0048667;anatomical structure development#GO:0048856;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699 neuron projection#GO:0043005;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886;axon#GO:0030424 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000001978.3|UniProtKB=F6X4A8 F6X4A8 PTHR43658:SF8 SHORT-CHAIN DEHYDROGENASE/REDUCTASE 17-BETA-HYDROXYSTEROID DEHYDROGENASE 14-RELATED oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000020033.1|UniProtKB=H2XN72 H2XN72 LOC100184853 PTHR15191:SF3 PROTEIN CBG20567 PITUITARY TUMOR-TRANSFORMING GENE PROTEIN-BINDING FACTOR cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;protein localization to nucleus#GO:0034504;nitrogen compound transport#GO:0071705;establishment of protein localization to organelle#GO:0072594;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;protein import into nucleus#GO:0006606;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;protein localization to organelle#GO:0033365;nuclear transport#GO:0051169;import into nucleus#GO:0051170 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000003363.2|UniProtKB=F7BA18 F7BA18 PTHR11630:SF42 DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER DNA REPLICATION LICENSING FACTOR MCM5 ATP-dependent activity, acting on DNA#GO:0008094;nucleic acid binding#GO:0003676;3'-5' DNA helicase activity#GO:0043138;helicase activity#GO:0004386;ATP-dependent activity#GO:0140657;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;single-stranded DNA binding#GO:0003697;DNA binding#GO:0003677;catalytic activity, acting on a nucleic acid#GO:0140640;DNA helicase activity#GO:0003678;catalytic activity, acting on DNA#GO:0140097;single-stranded DNA helicase activity#GO:0017116 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;double-strand break repair via homologous recombination#GO:0000724;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;response to stress#GO:0006950;double-strand break repair via break-induced replication#GO:0000727;nitrogen compound metabolic process#GO:0006807;recombinational repair#GO:0000725;DNA-templated DNA replication#GO:0006261;DNA replication#GO:0006260;cellular response to stress#GO:0033554;DNA replication initiation#GO:0006270;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259;metabolic process#GO:0008152 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;MCM complex#GO:0042555;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA metabolism protein#PC00009 Parkinson disease#P00049>Hsp70#P01208;Apoptosis signaling pathway#P00006>HSP70#P00321 CIOIN|Ensembl=ENSCING00000004705.3|UniProtKB=F6QN34 F6QN34 LOC100178767 PTHR11616:SF303 SODIUM/CHLORIDE DEPENDENT TRANSPORTER SODIUM- AND CHLORIDE-DEPENDENT GABA TRANSPORTER INE inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;organic acid:sodium symporter activity#GO:0005343;organic acid transmembrane transporter activity#GO:0005342;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;organic anion transmembrane transporter activity#GO:0008514;monoatomic cation transmembrane transporter activity#GO:0008324;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;amino acid:sodium symporter activity#GO:0005283;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;metal ion transmembrane transporter activity#GO:0046873;active monoatomic ion transmembrane transporter activity#GO:0022853;amino acid transmembrane transporter activity#GO:0015171;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;organic anion transport#GO:0015711;amino acid transport#GO:0006865;organic acid transport#GO:0015849;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;amino acid import across plasma membrane#GO:0089718;carboxylic acid transmembrane transport#GO:1905039;localization#GO:0051179;organic substance transport#GO:0071702;import across plasma membrane#GO:0098739;amino acid transmembrane transport#GO:0003333;sodium ion transport#GO:0006814;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transport#GO:0006812;organic acid transmembrane transport#GO:1903825;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;import into cell#GO:0098657;sodium ion transmembrane transport#GO:0035725 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 primary active transporter#PC00068;transporter#PC00227 CIOIN|Ensembl=ENSCING00000020864.1|UniProtKB=H2Y2F9 H2Y2F9 PTHR22984:SF29 SERINE/THREONINE-PROTEIN KINASE PIM SERINE_THREONINE-PROTEIN KINASE PIM-1 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;phosphorylation#GO:0016310;protein phosphorylation#GO:0006468;cellular process#GO:0009987;protein metabolic process#GO:0019538;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000006343.3|UniProtKB=F6PRU7 F6PRU7 LOC100181413 PTHR11959:SF10 4-HYDROXYPHENYLPYRUVATE DIOXYGENASE 4-HYDROXYPHENYLPYRUVATE DIOXYGENASE-LIKE PROTEIN oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;dioxygenase activity#GO:0051213 cellular aromatic compound metabolic process#GO:0006725;oxoacid metabolic process#GO:0043436;tyrosine metabolic process#GO:0006570;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;aromatic compound catabolic process#GO:0019439;aromatic amino acid metabolic process#GO:0009072;organic cyclic compound metabolic process#GO:1901360;small molecule catabolic process#GO:0044282;nitrogen compound metabolic process#GO:0006807;alpha-amino acid metabolic process#GO:1901605;organic cyclic compound catabolic process#GO:1901361;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;carboxylic acid metabolic process#GO:0019752;aromatic amino acid family catabolic process#GO:0009074;amino acid metabolic process#GO:0006520;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 oxygenase#PC00177;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000018399.1|UniProtKB=H2Y2W2 H2Y2W2 PTHR46022:SF1 PROTEIN PATCHED PROTEIN PATCHED cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 Hedgehog signaling pathway#P00025>Patched#P00689 CIOIN|Ensembl=ENSCING00000004206.3|UniProtKB=F7ALJ0 F7ALJ0 PTHR10361:SF28 SODIUM-BILE ACID COTRANSPORTER P3 PROTEIN-RELATED primary active transporter#PC00068;transporter#PC00227 CIOIN|Ensembl=ENSCING00000013160.2|UniProtKB=F6YFF3 F6YFF3 PTHR44324:SF1 WD40 REPEAT DOMAIN 95 WD REPEAT-CONTAINING PROTEIN 49 CIOIN|Ensembl=ENSCING00000022668.1|UniProtKB=H2XPZ0 H2XPZ0 PTHR11644:SF2 CYTIDINE DEAMINASE CYTIDINE DEAMINASE cation binding#GO:0043169;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;small molecule binding#GO:0036094;zinc ion binding#GO:0008270;binding#GO:0005488;catalytic activity#GO:0003824;transition metal ion binding#GO:0046914;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;metal ion binding#GO:0046872;deaminase activity#GO:0019239;ion binding#GO:0043167 cellular aromatic compound metabolic process#GO:0006725;nucleoside metabolic process#GO:0009116;glycosyl compound catabolic process#GO:1901658;carbohydrate derivative metabolic process#GO:1901135;heterocycle catabolic process#GO:0046700;pyrimidine-containing compound metabolic process#GO:0072527;organonitrogen compound catabolic process#GO:1901565;nucleobase-containing compound metabolic process#GO:0006139;cellular nitrogen compound catabolic process#GO:0044270;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;catabolic process#GO:0009056;nucleoside catabolic process#GO:0009164;organic substance catabolic process#GO:1901575;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248;heterocycle metabolic process#GO:0046483;carbohydrate derivative catabolic process#GO:1901136;cellular metabolic process#GO:0044237;organonitrogen compound metabolic process#GO:1901564;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;small molecule catabolic process#GO:0044282;aromatic compound catabolic process#GO:0019439;nucleobase-containing small molecule catabolic process#GO:0034656;organic cyclic compound catabolic process#GO:1901361;nucleobase-containing compound catabolic process#GO:0034655;glycosyl compound metabolic process#GO:1901657;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 deaminase#PC00088;hydrolase#PC00121 Salvage pyrimidine ribonucleotides#P02775>Cytidine deaminase#P03154;Salvage pyrimidine deoxyribonucleotides#P02774>Cytidine deaminase#P03144;Pyrimidine Metabolism#P02771>Cytidine Deaminase#P03130 CIOIN|Ensembl=ENSCING00000007425.3|UniProtKB=F7B7X5 F7B7X5 PTHR46006:SF8 RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR AT 64C, ISOFORM A DH DOMAIN-CONTAINING PROTEIN regulation of cell communication#GO:0010646;regulation of Rho protein signal transduction#GO:0035023;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;regulation of small GTPase mediated signal transduction#GO:0051056;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 CIOIN|Ensembl=ENSCING00000006669.3|UniProtKB=F6TCT1 F6TCT1 PTHR11453:SF36 ANION EXCHANGE PROTEIN ANION EXCHANGE PROTEIN secondary active transmembrane transporter activity#GO:0015291;inorganic molecular entity transmembrane transporter activity#GO:0015318;transmembrane transporter activity#GO:0022857;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;symporter activity#GO:0015293;active monoatomic ion transmembrane transporter activity#GO:0022853;solute:sodium symporter activity#GO:0015370;organic anion transmembrane transporter activity#GO:0008514;monoatomic cation transmembrane transporter activity#GO:0008324;monoatomic ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;inorganic cation transmembrane transporter activity#GO:0022890;transporter activity#GO:0005215;solute:monoatomic cation symporter activity#GO:0015294 regulation of intracellular pH#GO:0051453;transmembrane transport#GO:0055085;organic anion transport#GO:0015711;transport#GO:0006810;homeostatic process#GO:0042592;monoatomic cation homeostasis#GO:0055080;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;cellular process#GO:0009987;intracellular chemical homeostasis#GO:0055082;monoatomic ion homeostasis#GO:0050801;localization#GO:0051179;regulation of pH#GO:0006885;organic substance transport#GO:0071702;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;intracellular monoatomic cation homeostasis#GO:0030003;biological regulation#GO:0065007;intracellular monoatomic ion homeostasis#GO:0006873;regulation of cellular pH#GO:0030641 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000004073.3|UniProtKB=F7AN97 F7AN97 LOC100180593 PTHR12461:SF95 HYPOXIA-INDUCIBLE FACTOR 1 ALPHA INHIBITOR-RELATED JMJC DOMAIN-CONTAINING PROTEIN histone modifying activity#GO:0140993;demethylase activity#GO:0032451;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;histone demethylase activity#GO:0032452;catalytic activity#GO:0003824;dioxygenase activity#GO:0051213;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000017918.1|UniProtKB=H2XUH5 H2XUH5 PTHR24251:SF37 OVOCHYMASE-RELATED CUB DOMAIN-CONTAINING PROTEIN serine protease#PC00203;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000002752.3|UniProtKB=F7AHK9 F7AHK9 PTHR22855:SF47 ACETYL, PROPIONYL, PYRUVATE, AND GLUTACONYL CARBOXYLASE-RELATED METHYLCROTONOYL-COA CARBOXYLASE ligase activity#GO:0016874;catalytic activity#GO:0003824 oxoacid metabolic process#GO:0043436;branched-chain amino acid metabolic process#GO:0009081;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;amino acid catabolic process#GO:0009063;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;nitrogen compound metabolic process#GO:0006807;alpha-amino acid metabolic process#GO:1901605;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;carboxylic acid metabolic process#GO:0019752;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ligase#PC00142;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000001563.3|UniProtKB=F6XLN4 F6XLN4 PTHR23235:SF166 KRUEPPEL-LIKE TRANSCRIPTION FACTOR DENDRITIC ARBOR REDUCTION PROTEIN 1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 CIOIN|Ensembl=ENSCING00000016378.2|UniProtKB=F7AVK7 F7AVK7 LOC104265788 PTHR10454:SF244 CASPASE CASPASE-6-LIKE cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197;hydrolase activity#GO:0016787;cysteine-type endopeptidase activity involved in apoptotic process#GO:0097153;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0043280;positive regulation of cysteine-type endopeptidase activity#GO:2001056;regulation of protein metabolic process#GO:0051246;regulation of cysteine-type endopeptidase activity#GO:2000116;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;positive regulation of proteolysis#GO:0045862;regulation of biological process#GO:0050789;activation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0006919;positive regulation of programmed cell death#GO:0043068;positive regulation of metabolic process#GO:0009893;regulation of molecular function#GO:0065009;apoptotic process#GO:0006915;cell death#GO:0008219;regulation of hydrolase activity#GO:0051336;positive regulation of peptidase activity#GO:0010952;positive regulation of biological process#GO:0048518;regulation of programmed cell death#GO:0043067;positive regulation of apoptotic process#GO:0043065;regulation of proteolysis#GO:0030162;regulation of apoptotic process#GO:0042981;positive regulation of catalytic activity#GO:0043085;programmed cell death#GO:0012501;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of hydrolase activity#GO:0051345;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;positive regulation of protein metabolic process#GO:0051247;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of endopeptidase activity#GO:0052548;regulation of peptidase activity#GO:0052547;regulation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0043281;positive regulation of endopeptidase activity#GO:0010950;regulation of metabolic process#GO:0019222 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 protease#PC00190;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000006271.3|UniProtKB=F6VPV7 F6VPV7 PTHR46759:SF1 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 72 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 72 CIOIN|Ensembl=ENSCING00000006498.3|UniProtKB=F7AAV2 F7AAV2 PTHR11903:SF39 PROSTAGLANDIN G/H SYNTHASE PROSTAGLANDIN G_H SYNTHASE 2-LIKE oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;dioxygenase activity#GO:0051213 long-chain fatty acid metabolic process#GO:0001676;organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;monocarboxylic acid biosynthetic process#GO:0072330;icosanoid metabolic process#GO:0006690;cellular metabolic process#GO:0044237;icosanoid biosynthetic process#GO:0046456;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;prostaglandin metabolic process#GO:0006693;fatty acid metabolic process#GO:0006631;unsaturated fatty acid metabolic process#GO:0033559;unsaturated fatty acid biosynthetic process#GO:0006636;small molecule biosynthetic process#GO:0044283;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;fatty acid biosynthetic process#GO:0006633;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;neuron projection#GO:0043005;intracellular anatomical structure#GO:0005622 oxygenase#PC00177;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000003378.3|UniProtKB=F7A771 F7A771 PTHR11071:SF561 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE D-RELATED peptidyl-prolyl cis-trans isomerase activity#GO:0003755;isomerase activity#GO:0016853;catalytic activity, acting on a protein#GO:0140096;binding#GO:0005488;catalytic activity#GO:0003824;peptide binding#GO:0042277;amide binding#GO:0033218 macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein peptidyl-prolyl isomerization#GO:0000413;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein folding#GO:0006457;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 chaperone#PC00072 CIOIN|Ensembl=ENSCING00000020967.1|UniProtKB=A0A1W3JUM5 A0A1W3JUM5 zf(rbz) PTHR12999:SF17 ZINC FINGER RAN-BINDING DOMAIN-CONTAINING PROTEIN 2 ZRANB2-RELATED ZINC FINGER RAN-BINDING DOMAIN-CONTAINING PROTEIN 2 RNA splicing factor#PC00148;RNA processing factor#PC00147 CIOIN|Ensembl=ENSCING00000006579.3|UniProtKB=F6UPM0 F6UPM0 PTHR11616:SF321 SODIUM/CHLORIDE DEPENDENT TRANSPORTER SODIUM-DEPENDENT NUTRIENT AMINO ACID TRANSPORTER 1-RELATED inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;organic acid:sodium symporter activity#GO:0005343;organic acid transmembrane transporter activity#GO:0005342;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;organic anion transmembrane transporter activity#GO:0008514;monoatomic cation transmembrane transporter activity#GO:0008324;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;amino acid:sodium symporter activity#GO:0005283;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;metal ion transmembrane transporter activity#GO:0046873;active monoatomic ion transmembrane transporter activity#GO:0022853;amino acid transmembrane transporter activity#GO:0015171;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;organic anion transport#GO:0015711;amino acid transport#GO:0006865;organic acid transport#GO:0015849;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;amino acid import across plasma membrane#GO:0089718;carboxylic acid transmembrane transport#GO:1905039;localization#GO:0051179;organic substance transport#GO:0071702;import across plasma membrane#GO:0098739;amino acid transmembrane transport#GO:0003333;sodium ion transport#GO:0006814;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transport#GO:0006812;organic acid transmembrane transport#GO:1903825;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;import into cell#GO:0098657;sodium ion transmembrane transport#GO:0035725 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 primary active transporter#PC00068;transporter#PC00227 Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>CHT1#P01084 CIOIN|Ensembl=ENSCING00000010066.3|UniProtKB=F6QD73 F6QD73 PTHR13271:SF34 UNCHARACTERIZED PUTATIVE METHYLTRANSFERASE N-LYSINE METHYLTRANSFERASE SETD6 N-methyltransferase activity#GO:0008170;transferase activity#GO:0016740;catalytic activity#GO:0003824;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;protein-lysine N-methyltransferase activity#GO:0016279;catalytic activity, acting on a protein#GO:0140096;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;protein methyltransferase activity#GO:0008276;lysine N-methyltransferase activity#GO:0016278 macromolecule methylation#GO:0043414;methylation#GO:0032259;macromolecule modification#GO:0043412;nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;primary metabolic process#GO:0044238 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transferase#PC00220;methyltransferase#PC00155;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000004200.3|UniProtKB=F7AM14 F7AM14 LOC778981 PTHR48112:SF22 HIGH MOBILITY GROUP PROTEIN DSP1 MITOCHONDRIAL TRANSCRIPTION FACTOR A, ISOFORM B HMG box transcription factor#PC00024 CIOIN|Ensembl=ENSCING00000008551.3|UniProtKB=F6XQ16 F6XQ16 PTHR24356:SF390 SERINE/THREONINE-PROTEIN KINASE PROTEIN KINASE C, BRAIN ISOZYME-RELATED transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular process#GO:0009987;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Alzheimer disease-amyloid secretase pathway#P00003>PKC#P00109;PDGF signaling pathway#P00047>PKC#P01150;Endothelin signaling pathway#P00019>PKC#P00568;Angiogenesis#P00005>PKC#P00219;5HT2 type receptor mediated signaling pathway#P04374>PKC#P04420;EGF receptor signaling pathway#P00018>PKC#P00565;Histamine H1 receptor mediated signaling pathway#P04385>PKC#P04487;FGF signaling pathway#P00021>PKC#P00648;VEGF signaling pathway#P00056>PKC#P01425;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>PKC#P01074;Wnt signaling pathway#P00057>Protein Kinase C#P01458;Apoptosis signaling pathway#P00006>PKCs#P00318;Thyrotropin-releasing hormone receptor signaling pathway#P04394>PKC#P04583;Oxytocin receptor mediated signaling pathway#P04391>PKC#P04533 CIOIN|Ensembl=ENSCING00000004143.3|UniProtKB=F6UHT2 F6UHT2 PTHR43884:SF11 ACYL-COA DEHYDROGENASE VERY LONG-CHAIN SPECIFIC ACYL-COA DEHYDROGENASE, MITOCHONDRIAL carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;amide binding#GO:0033218;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;lipid binding#GO:0008289;anion binding#GO:0043168;ion binding#GO:0043167;oxidoreductase activity#GO:0016491 dehydrogenase#PC00092;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000001155.3|UniProtKB=F6YU98 F6YU98 LOC100182595 PTHR24073:SF209 DRAB5-RELATED RAS-RELATED PROTEIN RAB-23 GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;macroautophagy#GO:0016236;macromolecule localization#GO:0033036;transport#GO:0006810;nitrogen compound transport#GO:0071705;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;organelle assembly#GO:0070925;process utilizing autophagic mechanism#GO:0061919;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;vacuole organization#GO:0007033;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;organelle organization#GO:0006996;protein transport#GO:0015031;autophagosome assembly#GO:0000045;catabolic process#GO:0009056;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;autophagy#GO:0006914;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 bounding membrane of organelle#GO:0098588;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuole#GO:0005773;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endosome membrane#GO:0010008;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;autophagosome#GO:0005776;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle membrane#GO:0030659 small GTPase#PC00208;G-protein#PC00020 CIOIN|Ensembl=ENSCING00000023639.1|UniProtKB=A0A1W2WRD6 A0A1W2WRD6 LOC101242758 PTHR13041:SF3 JTB PROTEIN-RELATED PROTEIN JTB mitotic cytokinesis#GO:0000281;cell division#GO:0051301;mitotic cell cycle#GO:0000278;cytoskeleton-dependent cytokinesis#GO:0061640;cell cycle process#GO:0022402;cell cycle#GO:0007049;cellular process#GO:0009987;mitotic cell cycle process#GO:1903047;cytokinesis#GO:0000910 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;midbody#GO:0030496;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;spindle#GO:0005819;centrosome#GO:0005813;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000015101.2|UniProtKB=F7BF76 F7BF76 PTHR24369:SF212 ANTIGEN BSP, PUTATIVE-RELATED LEUCINE-RICH REPEAT-CONTAINING PROTEIN 4B-LIKE cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 CIOIN|Ensembl=ENSCING00000006068.3|UniProtKB=F6ZG25 F6ZG25 PTHR15414:SF0 OS-9-RELATED ENDOPLASMIC RETICULUM LECTIN 1 cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;protein catabolic process#GO:0030163;nitrogen compound transport#GO:0071705;organonitrogen compound catabolic process#GO:1901565;establishment of protein localization#GO:0045184;organic substance transport#GO:0071702;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;response to organic substance#GO:0010033;macromolecule catabolic process#GO:0009057;cellular response to stimulus#GO:0051716;response to endoplasmic reticulum stress#GO:0034976;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;ERAD pathway#GO:0036503;response to organonitrogen compound#GO:0010243;cellular process#GO:0009987;protein localization#GO:0008104;primary metabolic process#GO:0044238;localization#GO:0051179;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to stress#GO:0006950;cellular macromolecule localization#GO:0070727;response to chemical#GO:0042221;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;cellular response to stress#GO:0033554 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;endoplasmic reticulum lumen#GO:0005788;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000012472.2|UniProtKB=F6UTH5 F6UTH5 PTHR21549:SF0 MUTATED IN BLADDER CANCER 1 COILED-COIL DOMAIN-CONTAINING PROTEIN 112 CIOIN|Ensembl=ENSCING00000012009.2|UniProtKB=F7B779 F7B779 PTHR45796:SF4 FORKHEAD BOX P, ISOFORM C FORKHEAD BOX P, ISOFORM C sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 CIOIN|Ensembl=ENSCING00000008667.3|UniProtKB=F6ZFG0 F6ZFG0 PTHR43329:SF15 EPOXIDE HYDROLASE HALOALKANE DEHALOGENASE hydrolase activity#GO:0016787;catalytic activity#GO:0003824 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000023649.1|UniProtKB=H2XSJ3 H2XSJ3 LOC100175262 PTHR12452:SF0 42-9-9 PROTEIN-RELATED THIOREDOXIN DOMAIN-CONTAINING PROTEIN 17 protein-disulfide reductase activity#GO:0015035;disulfide oxidoreductase activity#GO:0015036;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 transporter#PC00227 CIOIN|Ensembl=ENSCING00000000323.3|UniProtKB=F6YXT1 F6YXT1 LOC100186405 PTHR13551:SF2 BRAIN PROTEIN I3 BRAIN PROTEIN I3 CIOIN|Ensembl=ENSCING00000007289.3|UniProtKB=F7AFR6 F7AFR6 LOC100180605 PTHR44145:SF3 DNAJ HOMOLOG SUBFAMILY A MEMBER 3, MITOCHONDRIAL DNAJ HOMOLOG SUBFAMILY A MEMBER 3, MITOCHONDRIAL chaperone#PC00072 CIOIN|Ensembl=ENSCING00000009602.3|UniProtKB=F7AWU8 F7AWU8 PTHR45973:SF8 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT SDS22-RELATED LEUCINE-RICH REPEAT-CONTAINING PROTEIN 49 phosphatase modulator#PC00184 CIOIN|Ensembl=ENSCING00000004764.3|UniProtKB=F6PMD1 F6PMD1 LOC100182764 PTHR22761:SF12 CHARGED MULTIVESICULAR BODY PROTEIN CHARGED MULTIVESICULAR BODY PROTEIN 5 endosomal transport#GO:0016197;cellular localization#GO:0051641;membrane organization#GO:0061024;vacuolar transport#GO:0007034;transport#GO:0006810;late endosome to vacuole transport via multivesicular body sorting pathway#GO:0032511;vesicle-mediated transport#GO:0016192;late endosome to vacuole transport#GO:0045324;cellular component organization#GO:0016043;cellular process#GO:0009987;multivesicular body sorting pathway#GO:0071985;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;vesicle budding from membrane#GO:0006900;establishment of localization#GO:0051234;organelle organization#GO:0006996;endosome transport via multivesicular body sorting pathway#GO:0032509;establishment of localization in cell#GO:0051649;vesicle organization#GO:0016050;intracellular transport#GO:0046907 cytoplasm#GO:0005737;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular vesicle#GO:0097708;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;late endosome#GO:0005770;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150 CIOIN|Ensembl=ENSCING00000009518.3|UniProtKB=F6WWY2 F6WWY2 PTHR10827:SF102 RETICULOCALBIN EF-HAND DOMAIN-CONTAINING PROTEIN calmodulin-related#PC00061 CIOIN|Ensembl=ENSCING00000011358.2|UniProtKB=F6U959 F6U959 PTHR12157:SF21 REGULATING SYNAPTIC MEMBRANE EXOCYTOSIS PROTEIN RAB3 INTERACTING MOLECULE, ISOFORM F membrane traffic protein#PC00150 CIOIN|Ensembl=ENSCING00000012109.2|UniProtKB=F6X6B7 F6X6B7 PTHR11532:SF94 PROTEASE M14 CARBOXYPEPTIDASE CARBOXYPEPTIDASE D-LIKE metalloexopeptidase activity#GO:0008235;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;metallocarboxypeptidase activity#GO:0004181;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;carboxypeptidase activity#GO:0004180 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;protein processing#GO:0016485;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 protease#PC00190;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000009226.3|UniProtKB=Q4H3H4 Q4H3H4 Ci-Fringe 1 PTHR10811:SF5 FRINGE-RELATED FRINGE GLYCOSYLTRANSFERASE acetylglucosaminyltransferase activity#GO:0008375;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194;hexosyltransferase activity#GO:0016758 glycosyltransferase#PC00111;metabolite interconversion enzyme#PC00262 Notch signaling pathway#P00045>Fringe#P01107 CIOIN|Ensembl=ENSCING00000009628.3|UniProtKB=F6ZUP0 F6ZUP0 PTHR10288:SF171 KH DOMAIN CONTAINING RNA BINDING PROTEIN P-ELEMENT SOMATIC INHIBITOR, ISOFORM C nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of biosynthetic process#GO:0009889;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000016484.2|UniProtKB=F6S2B0 F6S2B0 PTHR43975:SF2 ZGC:101858 EG:BACR7A4.14 PROTEIN-RELATED CIOIN|Ensembl=ENSCING00000006811.3|UniProtKB=F6UMK9 F6UMK9 LOC100186482 PTHR22950:SF244 AMINO ACID TRANSPORTER NEUTRAL AMINO ACID TRANSPORTER 9 L-amino acid transmembrane transporter activity#GO:0015179;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;amino acid transmembrane transporter activity#GO:0015171;organic anion transmembrane transporter activity#GO:0008514;organic acid transmembrane transporter activity#GO:0005342;transporter activity#GO:0005215 localization#GO:0051179;organic substance transport#GO:0071702;amino acid transmembrane transport#GO:0003333;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;organic anion transport#GO:0015711;amino acid transport#GO:0006865;organic acid transport#GO:0015849;transport#GO:0006810;nitrogen compound transport#GO:0071705;organic acid transmembrane transport#GO:1903825;carboxylic acid transport#GO:0046942;cellular process#GO:0009987;carboxylic acid transmembrane transport#GO:1905039 bounding membrane of organelle#GO:0098588;lytic vacuole membrane#GO:0098852;intracellular membrane-bounded organelle#GO:0043231;vacuolar membrane#GO:0005774;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;lytic vacuole#GO:0000323;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;lysosomal membrane#GO:0005765;lysosome#GO:0005764;membrane-bounded organelle#GO:0043227 amino acid transporter#PC00046;transporter#PC00227 CIOIN|Ensembl=ENSCING00000003592.3|UniProtKB=F6XJF3 F6XJF3 PTHR12308:SF74 ANOCTAMIN ANOCTAMIN inorganic molecular entity transmembrane transporter activity#GO:0015318;chloride channel activity#GO:0005254;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;chloride transmembrane transporter activity#GO:0015108;monoatomic anion transmembrane transporter activity#GO:0008509;inorganic anion transmembrane transporter activity#GO:0015103;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267;monoatomic ion channel activity#GO:0005216 localization#GO:0051179;inorganic anion transmembrane transport#GO:0098661;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic anion transmembrane transport#GO:0098656;monoatomic ion transmembrane transport#GO:0034220;monoatomic anion transport#GO:0006820;transport#GO:0006810;chloride transport#GO:0006821;chloride transmembrane transport#GO:1902476;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 CIOIN|Ensembl=ENSCING00000003865.3|UniProtKB=F6Y4W3 F6Y4W3 PTHR24064:SF577 SOLUTE CARRIER FAMILY 22 MEMBER GH09241P secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000006286.3|UniProtKB=F6UCG0 F6UCG0 PTHR11361:SF35 DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER DNA MISMATCH REPAIR PROTEIN MSH2 nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;mismatch repair#GO:0006298;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;DNA damage response#GO:0006974;response to stress#GO:0006950;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;mitotic recombination#GO:0006312;cellular response to stress#GO:0033554;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA metabolism protein#PC00009 CIOIN|Ensembl=ENSCING00000003506.3|UniProtKB=F7BHR3 F7BHR3 PTHR13165:SF0 ARSENITE-RESISTANCE PROTEIN 2 SERRATE RNA EFFECTOR MOLECULE HOMOLOG negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;RNA metabolic process#GO:0016070;regulatory ncRNA processing#GO:0070918;RNA processing#GO:0006396;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulatory ncRNA-mediated gene silencing#GO:0031047;miRNA processing#GO:0035196;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary miRNA processing#GO:0031053;primary metabolic process#GO:0044238;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear body#GO:0016604;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000015859.2|UniProtKB=F6ZJB9 F6ZJB9 PTHR15415:SF7 MITOFILIN MICOS COMPLEX SUBUNIT MIC60 CIOIN|Ensembl=ENSCING00000019956.1|UniProtKB=H2Y181 H2Y181 PTHR22901:SF0 SIALATE O-ACETYLESTERASE SIALATE O-ACETYLESTERASE hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 carbohydrate metabolic process#GO:0005975;organic substance metabolic process#GO:0071704;primary metabolic process#GO:0044238;metabolic process#GO:0008152 esterase#PC00097 CIOIN|Ensembl=ENSCING00000003909.3|UniProtKB=F6SLT5 F6SLT5 PTHR11533:SF276 PROTEASE M1 ZINC METALLOPROTEASE GLUTAMYL AMINOPEPTIDASE metalloexopeptidase activity#GO:0008235;metallopeptidase activity#GO:0008237;small molecule binding#GO:0036094;zinc ion binding#GO:0008270;binding#GO:0005488;catalytic activity#GO:0003824;transition metal ion binding#GO:0046914;amide binding#GO:0033218;metal ion binding#GO:0046872;peptidase activity#GO:0008233;metalloaminopeptidase activity#GO:0070006;cation binding#GO:0043169;peptide binding#GO:0042277;hydrolase activity#GO:0016787;aminopeptidase activity#GO:0004177;exopeptidase activity#GO:0008238;ion binding#GO:0043167;catalytic activity, acting on a protein#GO:0140096 macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;peptide catabolic process#GO:0043171;cellular process#GO:0009987;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;membrane#GO:0016020;extracellular region#GO:0005576;intracellular anatomical structure#GO:0005622 metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000012179.2|UniProtKB=F6TUN7 F6TUN7 LOC100175511 PTHR31761:SF1 GROWTH ARREST AND DNA DAMAGE-INDUCIBLE PROTEINS-INTERACTING PROTEIN 1 GADD45GIP1 LARGE RIBOSOMAL SUBUNIT PROTEIN ML64 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000005234.3|UniProtKB=F6YH10 F6YH10 PTHR10537:SF3 DNA PRIMASE LARGE SUBUNIT DNA PRIMASE LARGE SUBUNIT cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;DNA-templated DNA replication#GO:0006261;aromatic compound biosynthetic process#GO:0019438;DNA replication#GO:0006260;DNA replication initiation#GO:0006270;DNA metabolic process#GO:0006259;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 DNA metabolism protein#PC00009;primase#PC00189 DNA replication#P00017>Primase#P00528 CIOIN|Ensembl=ENSCING00000020135.1|UniProtKB=H2Y3N6 H2Y3N6 LOC100183893 PTHR11370:SF5 DNA-REPAIR PROTEIN XRCC1 DNA REPAIR PROTEIN XRCC1 DNA metabolism protein#PC00009 CIOIN|Ensembl=ENSCING00000004182.3|UniProtKB=F7B5M3 F7B5M3 PTHR31350:SF21 SI:DKEY-261L7.2 F-BOX ONLY PROTEIN 21 CIOIN|Ensembl=ENSCING00000015684.2|UniProtKB=F6WIP7 F6WIP7 PTHR11106:SF72 GANGLIOSIDE INDUCED DIFFERENTIATION ASSOCIATED PROTEIN 2-RELATED GANGLIOSIDE-INDUCED DIFFERENTIATION-ASSOCIATED PROTEIN 2 CIOIN|Ensembl=ENSCING00000007752.3|UniProtKB=F6YFK6 F6YFK6 ets PTHR11849:SF304 ETS DNA-BINDING PROTEIN D-ETS-3 transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 CIOIN|Ensembl=ENSCING00000017572.2|UniProtKB=Q4H3R0 Q4H3R0 Ci-DAN PTHR15283:SF4 GREMLIN 1 BURSICON molecular function activator activity#GO:0140677;binding#GO:0005488;molecular function regulator activity#GO:0098772;cytokine binding#GO:0019955;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;signaling receptor binding#GO:0005102 regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;negative regulation of response to stimulus#GO:0048585;animal organ development#GO:0048513;developmental process#GO:0032502;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of BMP signaling pathway#GO:0030510;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;negative regulation of BMP signaling pathway#GO:0030514;anatomical structure morphogenesis#GO:0009653;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;animal organ morphogenesis#GO:0009887;regulation of cellular response to growth factor stimulus#GO:0090287;negative regulation of signal transduction#GO:0009968;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 CIOIN|Ensembl=ENSCING00000003644.3|UniProtKB=F7AXJ1 F7AXJ1 LOC100185135 PTHR19211:SF15 ATP-BINDING TRANSPORT PROTEIN-RELATED ATP-BINDING CASSETTE SUB-FAMILY F MEMBER 2 nucleotide binding#GO:0000166;carbohydrate derivative binding#GO:0097367;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;anion binding#GO:0043168;ATP binding#GO:0005524 translation elongation factor#PC00222;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000008771.3|UniProtKB=F6SZQ0 F6SZQ0 PTHR11937:SF526 ACTIN ACTIN, CYTOPLASMIC 1-RELATED intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 actin and actin related protein#PC00039;cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 Integrin signalling pathway#P00034>Actin#P00944;Alzheimer disease-presenilin pathway#P00004>actin#P00114;Nicotinic acetylcholine receptor signaling pathway#P00044>Actin#P01090;Huntington disease#P00029>Actin#P00807;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>F-actin#P00858;Cadherin signaling pathway#P00012>F-actin#P00470;Cytoskeletal regulation by Rho GTPase#P00016>Actin#P00512 CIOIN|Ensembl=ENSCING00000022162.1|UniProtKB=H2XY10 H2XY10 PTHR10652:SF0 ADENYLYL CYCLASE-ASSOCIATED PROTEIN ADENYLYL CYCLASE-ASSOCIATED PROTEIN cytoskeletal protein binding#GO:0008092;enzyme binding#GO:0019899;protein binding#GO:0005515;actin binding#GO:0003779;binding#GO:0005488 signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;actin filament-based process#GO:0030029;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;biological regulation#GO:0065007;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;intracellular signaling cassette#GO:0141124;intracellular signal transduction#GO:0035556;actin cytoskeleton organization#GO:0030036;signaling#GO:0023052;cAMP-mediated signaling#GO:0019933;cyclic-nucleotide-mediated signaling#GO:0019935 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 CIOIN|Ensembl=ENSCING00000009186.3|UniProtKB=F6YLZ5 F6YLZ5 rfx1_2_3 PTHR12619:SF33 RFX TRANSCRIPTION FACTOR FAMILY RFX, ISOFORM H sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 CIOIN|Ensembl=ENSCING00000007236.3|UniProtKB=F6UW46 F6UW46 LOC100184014 PTHR11871:SF0 PROTEIN PHOSPHATASE PP2A REGULATORY SUBUNIT B PROTEIN PHOSPHATASE PP2A 55 KDA REGULATORY SUBUNIT phosphatase regulator activity#GO:0019208;molecular function regulator activity#GO:0098772;protein phosphatase regulator activity#GO:0019888;enzyme regulator activity#GO:0030234 protein serine/threonine phosphatase complex#GO:0008287;cytoplasm#GO:0005737;cytosol#GO:0005829;protein-containing complex#GO:0032991;cellular anatomical entity#GO:0110165;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622 protein phosphatase#PC00195;protein modifying enzyme#PC00260 FGF signaling pathway#P00021>PP2A#P00629 CIOIN|Ensembl=ENSCING00000014657.2|UniProtKB=F7BHZ3 F7BHZ3 PTHR13132:SF29 ALPHA- 1,6 -FUCOSYLTRANSFERASE ALPHA-(1,6)-FUCOSYLTRANSFERASE transferase activity#GO:0016740;fucosyltransferase activity#GO:0008417;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein glycosylation#GO:0006486;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein N-linked glycosylation#GO:0006487;protein metabolic process#GO:0019538;glycosylation#GO:0070085;glycoprotein metabolic process#GO:0009100;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 glycosyltransferase#PC00111 Notch signaling pathway#P00045>Neurotic#P01115 CIOIN|Ensembl=ENSCING00000004776.3|UniProtKB=F6PLX2 F6PLX2 PTHR28004:SF2 ZGC:162816-RELATED D-SERINE DEHYDRATASE lyase activity#GO:0016829;catalytic activity#GO:0003824 oxoacid metabolic process#GO:0043436;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;amino acid catabolic process#GO:0009063;small molecule catabolic process#GO:0044282;nitrogen compound metabolic process#GO:0006807;alpha-amino acid metabolic process#GO:1901605;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;carboxylic acid metabolic process#GO:0019752;amino acid metabolic process#GO:0006520;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 CIOIN|Ensembl=ENSCING00000006772.3|UniProtKB=F6XAM7 F6XAM7 PTHR11348:SF17 CONNECTIVE TISSUE GROWTH FACTOR-RELATED CCN carbohydrate derivative binding#GO:0097367;integrin binding#GO:0005178;binding#GO:0005488;heparin binding#GO:0008201;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;glycosaminoglycan binding#GO:0005539;signaling receptor binding#GO:0005102 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;positive regulation of cell differentiation#GO:0045597;cell communication#GO:0007154;cell adhesion#GO:0007155;cellular process#GO:0009987;regulation of cell differentiation#GO:0045595;positive regulation of developmental process#GO:0051094;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;biological regulation#GO:0065007;signaling#GO:0023052;positive regulation of biological process#GO:0048518 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;extracellular space#GO:0005615;extracellular region#GO:0005576 growth factor#PC00112 CIOIN|Ensembl=ENSCING00000023290.1|UniProtKB=F6SKP5 F6SKP5 PTHR11575:SF48 5'-NUCLEOTIDASE-RELATED 5'-NUCLEOTIDASE phosphodiesterase#PC00185;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000020159.1|UniProtKB=H2XPM9 H2XPM9 PTHR10476:SF17 CHARGED MULTIVESICULAR BODY PROTEIN CHARGED MULTIVESICULAR BODY PROTEIN 1A endosomal transport#GO:0016197;cellular localization#GO:0051641;macromolecule localization#GO:0033036;vacuolar transport#GO:0007034;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;late endosome to vacuole transport#GO:0045324;cellular process#GO:0009987;multivesicular body sorting pathway#GO:0071985;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;endosome transport via multivesicular body sorting pathway#GO:0032509;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endosome membrane#GO:0010008;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle membrane#GO:0030659;late endosome#GO:0005770 membrane traffic protein#PC00150 CIOIN|Ensembl=ENSCING00000023194.1|UniProtKB=H2XUW8 H2XUW8 PTHR47266:SF31 ENDONUCLEASE-RELATED RNA-DIRECTED DNA POLYMERASE CIOIN|Ensembl=ENSCING00000008151.3|UniProtKB=F6VFC5 F6VFC5 LOC100181789 PTHR45916:SF1 STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 5 STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 5 nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;single-stranded DNA binding#GO:0003697;DNA binding#GO:0003677 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;double-strand break repair via homologous recombination#GO:0000724;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;response to stress#GO:0006950;nitrogen compound metabolic process#GO:0006807;recombinational repair#GO:0000725;cellular response to stress#GO:0033554;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;catalytic complex#GO:1902494;transferase complex#GO:1990234;condensed chromosome#GO:0000793;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000004617.3|UniProtKB=F6Q0H1 F6Q0H1 PTHR24033:SF224 EGF-LIKE DOMAIN-CONTAINING PROTEIN C-TYPE LECTIN CIOIN|Ensembl=ENSCING00000016442.2|UniProtKB=F7BC32 F7BC32 LOC100183394 PTHR20900:SF0 NADH:UBIQUINONE OXIDOREDUCTASE B18-LIKE SUBUNIT NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 7 envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;respiratory chain complex#GO:0098803;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transporter complex#GO:1990351;oxidoreductase complex#GO:1990204;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;respirasome#GO:0070469;mitochondrial respiratory chain complex I#GO:0005747;protein-containing complex#GO:0032991;mitochondrial envelope#GO:0005740;inner mitochondrial membrane protein complex#GO:0098800;transmembrane transporter complex#GO:1902495;mitochondrial respirasome#GO:0005746;membrane-bounded organelle#GO:0043227;respiratory chain complex I#GO:0045271;NADH dehydrogenase complex#GO:0030964;mitochondrial protein-containing complex#GO:0098798 oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000006595.3|UniProtKB=F6QW12 F6QW12 PTHR34490:SF1 PROTEIN CBG12054-RELATED GALAXIN-LIKE CIOIN|Ensembl=ENSCING00000013724.2|UniProtKB=F6PMI7 F6PMI7 zf(u1like)-5 PTHR45762:SF3 ZINC FINGER RNA-BINDING PROTEIN ZINC-FINGER PROTEIN AT 72D, ISOFORM B RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000006372.3|UniProtKB=F6Q0U4 F6Q0U4 LOC100176724 PTHR11353:SF21 CHAPERONIN CHAPERONIN CONTAINING TCP1 SUBUNIT 6A-RELATED protein binding#GO:0005515;unfolded protein binding#GO:0051082;binding#GO:0005488 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein folding#GO:0006457;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;chaperonin-containing T-complex#GO:0005832;protein folding chaperone complex#GO:0101031;intracellular anatomical structure#GO:0005622 chaperonin#PC00073 CIOIN|Ensembl=ENSCING00000019383.1|UniProtKB=F6S9Q0 F6S9Q0 PTHR11984:SF53 CONNEXIN GAP JUNCTION PROTEIN wide pore channel activity#GO:0022829;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;channel activity#GO:0015267 biological regulation#GO:0065007;regulation of biological process#GO:0050789;cell communication#GO:0007154;cellular process#GO:0009987;cell-cell signaling#GO:0007267;signaling#GO:0023052 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 cell junction protein#PC00070;gap junction#PC00105 CIOIN|Ensembl=ENSCING00000006305.3|UniProtKB=F6PWI5 F6PWI5 LOC100179911 PTHR10574:SF375 NETRIN/LAMININ-RELATED LAMININ SUBUNIT BETA-1 neuron projection guidance#GO:0097485;cellular component biogenesis#GO:0044085;neurogenesis#GO:0022008;cell projection organization#GO:0030030;animal organ development#GO:0048513;developmental process#GO:0032502;substrate adhesion-dependent cell spreading#GO:0034446;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;extracellular matrix organization#GO:0030198;cellular anatomical entity morphogenesis#GO:0032989;system development#GO:0048731;cell differentiation#GO:0030154;axon guidance#GO:0007411;anatomical structure morphogenesis#GO:0009653;external encapsulating structure organization#GO:0045229;neuron differentiation#GO:0030182;axonogenesis#GO:0007409;plasma membrane bounded cell projection morphogenesis#GO:0120039;cellular developmental process#GO:0048869;cellular component assembly#GO:0022607;multicellular organism development#GO:0007275;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;cell adhesion#GO:0007155;cell motility#GO:0048870;cell-substrate adhesion#GO:0031589;cellular process#GO:0009987;tissue development#GO:0009888;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;extracellular structure organization#GO:0043062;cell morphogenesis involved in neuron differentiation#GO:0048667;anatomical structure development#GO:0048856;animal organ morphogenesis#GO:0009887;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;cell migration#GO:0016477 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;basement membrane#GO:0005604 extracellular matrix protein#PC00102 Integrin signalling pathway#P00034>Laminin#P00947 CIOIN|Ensembl=ENSCING00000018255.1|UniProtKB=H2XN21 H2XN21 PTHR12871:SF0 BETA-1,2-N-ACETYLGLUCOSAMINYLTRANSFERASE II ALPHA-1,6-MANNOSYL-GLYCOPROTEIN 2-BETA-N-ACETYLGLUCOSAMINYLTRANSFERASE acetylglucosaminyltransferase activity#GO:0008375;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;UDP-glycosyltransferase activity#GO:0008194 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein N-linked glycosylation#GO:0006487;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 bounding membrane of organelle#GO:0098588;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;Golgi membrane#GO:0000139;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111 CIOIN|Ensembl=ENSCING00000002324.3|UniProtKB=F6PNZ0 F6PNZ0 LOC100179178 PTHR31716:SF1 PROTEIN FMC1 HOMOLOG PROTEIN FMC1 HOMOLOG cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000006537.3|UniProtKB=F6RPW8 F6RPW8 LOC100184517 PTHR12046:SF0 HISTONE ACETYLTRANSFERASE TYPE B CATALYTIC SUBUNIT HISTONE ACETYLTRANSFERASE TYPE B CATALYTIC SUBUNIT histone modifying activity#GO:0140993;histone acetyltransferase activity#GO:0004402;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;N-acetyltransferase activity#GO:0008080;acyltransferase activity#GO:0016746;acetyltransferase activity#GO:0016407;peptide-lysine-N-acetyltransferase activity#GO:0061733;peptide N-acetyltransferase activity#GO:0034212;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;N-acyltransferase activity#GO:0016410 histone modifying enzyme#PC00261 CIOIN|Ensembl=ENSCING00000007298.3|UniProtKB=F6S7J0 F6S7J0 LOC100181381 PTHR23322:SF96 FAS-ASSOCIATED PROTEIN FAS-ASSOCIATED FACTOR 1 protein binding#GO:0005515;ubiquitin-like protein binding#GO:0032182;binding#GO:0005488;ubiquitin binding#GO:0043130 response to organic substance#GO:0010033;macromolecule catabolic process#GO:0009057;cellular response to stimulus#GO:0051716;response to endoplasmic reticulum stress#GO:0034976;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;response to organonitrogen compound#GO:0010243;ERAD pathway#GO:0036503;cellular process#GO:0009987;primary metabolic process#GO:0044238;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;cellular response to stress#GO:0033554;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 FAS signaling pathway#P00020>FAF1#P00609 CIOIN|Ensembl=ENSCING00000002397.3|UniProtKB=F6QZG4 F6QZG4 LOC100186141 PTHR14791:SF29 BOMB/KIRA PROTEINS PROTEIN KIBRA CIOIN|Ensembl=ENSCING00000012135.2|UniProtKB=F6UIL0 F6UIL0 PTHR40446:SF2 N-ACETYLGLUCOSAMINE-1-PHOSPHODIESTER ALPHA-N-ACETYLGLUCOSAMINIDASE N-ACETYLGLUCOSAMINE-1-PHOSPHODIESTER ALPHA-N-ACETYLGLUCOSAMINIDASE CIOIN|Ensembl=ENSCING00000020646.1|UniProtKB=F6W5Z3 F6W5Z3 PTHR11929:SF145 ALPHA- 1,3 -FUCOSYLTRANSFERASE ALPHA-(1,3)-FUCOSYLTRANSFERASE FUT-1 transferase activity#GO:0016740;fucosyltransferase activity#GO:0008417;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 glycosylation#GO:0070085;metabolic process#GO:0008152 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000005108.3|UniProtKB=F6WJZ0 F6WJZ0 LOC100184253 PTHR45896:SF1 N-ALPHA-ACETYLTRANSFERASE 30 N-ALPHA-ACETYLTRANSFERASE 30 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;N-acetyltransferase activity#GO:0008080;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acetyltransferase activity#GO:0016407;peptide N-acetyltransferase activity#GO:0034212;catalytic activity#GO:0003824;peptide alpha-N-acetyltransferase activity#GO:0004596;N-acyltransferase activity#GO:0016410 cytoplasm#GO:0005737;protein acetyltransferase complex#GO:0031248;protein-containing complex#GO:0032991;acetyltransferase complex#GO:1902493;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 acetyltransferase#PC00038 CIOIN|Ensembl=ENSCING00000004395.3|UniProtKB=F7AU71 F7AU71 PTHR10838:SF20 SYNAPTOGYRIN SYNAPTOGYRIN synaptic vesicle membrane#GO:0030672;bounding membrane of organelle#GO:0098588;presynapse#GO:0098793;synapse#GO:0045202;synaptic vesicle#GO:0008021;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;cell junction#GO:0030054;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;vesicle membrane#GO:0012506;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;transport vesicle membrane#GO:0030658;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;transport vesicle#GO:0030133;cytoplasmic vesicle membrane#GO:0030659;secretory vesicle#GO:0099503;neuromuscular junction#GO:0031594 membrane trafficking regulatory protein#PC00151 CIOIN|Ensembl=ENSCING00000014397.2|UniProtKB=F6ZX95 F6ZX95 PTHR19325:SF567 COMPLEMENT COMPONENT-RELATED SUSHI DOMAIN-CONTAINING SUSHI, VON WILLEBRAND FACTOR TYPE A, EGF AND PENTRAXIN DOMAIN-CONTAINING PROTEIN 1-LIKE complement component#PC00078 CIOIN|Ensembl=ENSCING00000000841.3|UniProtKB=F6R192 F6R192 LOC100182904 PTHR14677:SF20 ARSENITE INDUCUBLE RNA ASSOCIATED PROTEIN AIP-1-RELATED ZINC FINGER AN1-TYPE CONTAINING 2A-RELATED RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000009387.3|UniProtKB=F6WBC7 F6WBC7 foxf PTHR46262:SF2 FORKHEAD BOX PROTEIN BINIOU FORKHEAD BOX PROTEIN BINIOU sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;animal organ development#GO:0048513;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;anatomical structure morphogenesis#GO:0009653;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;animal organ morphogenesis#GO:0009887;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 CIOIN|Ensembl=ENSCING00000004677.3|UniProtKB=F6RBT7 F6RBT7 PTHR12820:SF0 VACUOLAR SORTING PROTEIN 53 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 53 HOMOLOG localization#GO:0051179;endosomal transport#GO:0016197;cellular localization#GO:0051641;establishment of localization#GO:0051234;transport#GO:0006810;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;cellular process#GO:0009987;cytosolic transport#GO:0016482;retrograde transport, endosome to Golgi#GO:0042147 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular vesicle#GO:0097708;vesicle tethering complex#GO:0099023;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150 CIOIN|Ensembl=ENSCING00000021743.1|UniProtKB=F6Y9P0 F6Y9P0 LOC100180490 PTHR12461:SF42 HYPOXIA-INDUCIBLE FACTOR 1 ALPHA INHIBITOR-RELATED JMJC DOMAIN-CONTAINING PROTEIN protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000003136.3|UniProtKB=F6RBY6 F6RBY6 LOC494377 PTHR12011:SF471 ADHESION G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 2 PROFILE 2 DOMAIN-CONTAINING PROTEIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 CIOIN|Ensembl=ENSCING00000017976.1|UniProtKB=H2XTX4 H2XTX4 LOC100181609 PTHR11505:SF210 L1 TRANSPOSABLE ELEMENT-RELATED UBIQUITIN-LIKE PROTEASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN single-stranded RNA binding#GO:0003727;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 CIOIN|Ensembl=ENSCING00000008994.3|UniProtKB=F6PKD1 F6PKD1 LOC100175816 PTHR14027:SF2 RNA POLYMERASE-ASSOCIATED PROTEIN CTR9 RNA POLYMERASE-ASSOCIATED PROTEIN CTR9 HOMOLOG basal RNA polymerase II transcription machinery binding#GO:0001099;RNA polymerase binding#GO:0070063;binding#GO:0005488;RNA polymerase core enzyme binding#GO:0043175;RNA polymerase II complex binding#GO:0000993;protein binding#GO:0005515;enzyme binding#GO:0019899;basal transcription machinery binding#GO:0001098 cellular aromatic compound metabolic process#GO:0006725;DNA-templated transcription#GO:0006351;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;DNA-templated transcription elongation#GO:0006354;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;RNA biosynthetic process#GO:0032774;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nucleobase-containing compound biosynthetic process#GO:0034654;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;aromatic compound biosynthetic process#GO:0019438;transcription elongation by RNA polymerase II#GO:0006368;transcription by RNA polymerase II#GO:0006366;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;DNA-directed RNA polymerase complex#GO:0000428;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;transcription elongation factor complex#GO:0008023;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695;RNA polymerase II, holoenzyme#GO:0016591;RNA polymerase complex#GO:0030880;protein-containing complex#GO:0032991;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;Cdc73/Paf1 complex#GO:0016593;nuclear protein-containing complex#GO:0140513 RNA metabolism protein#PC00031;general transcription factor#PC00259 CIOIN|Ensembl=ENSCING00000018015.1|UniProtKB=H2XMD3 H2XMD3 PTHR46799:SF2 HOMEOBOX PROTEIN UNC-4 HOMOLOG HOMEOBOX DOMAIN-CONTAINING PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of biosynthetic process#GO:0009889;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 CIOIN|Ensembl=ENSCING00000003511.3|UniProtKB=F6TLB6 F6TLB6 PTHR10194:SF142 RAS GTPASE-ACTIVATING PROTEINS NEUROFIBROMIN G-protein modulator#PC00022;protein-binding activity modulator#PC00095;GTPase-activating protein#PC00257 EGF receptor signaling pathway#P00018>GAP#P00546 CIOIN|Ensembl=ENSCING00000017513.2|UniProtKB=F6T172 F6T172 PTHR16146:SF46 INTELECTIN INTELECTIN-1A-RELATED CIOIN|Ensembl=ENSCING00000004504.3|UniProtKB=F7BBP3 F7BBP3 PTHR11412:SF139 MACROGLOBULIN / COMPLEMENT C3 AND PZP-LIKE ALPHA-2-MACROGLOBULIN DOMAIN-CONTAINING PROTEIN 8 protease inhibitor#PC00191 CIOIN|Ensembl=ENSCING00000007440.3|UniProtKB=F7AP04 F7AP04 PTHR12555:SF13 UBIQUITIN FUSION DEGRADATON PROTEIN 1 UBIQUITIN RECOGNITION FACTOR IN ER-ASSOCIATED DEGRADATION PROTEIN 1 protein binding#GO:0005515;binding#GO:0005488;polyubiquitin modification-dependent protein binding#GO:0031593;modification-dependent protein binding#GO:0140030 response to organic substance#GO:0010033;macromolecule catabolic process#GO:0009057;cellular response to stimulus#GO:0051716;response to endoplasmic reticulum stress#GO:0034976;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;response to organonitrogen compound#GO:0010243;ERAD pathway#GO:0036503;cellular process#GO:0009987;primary metabolic process#GO:0044238;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;cellular response to stress#GO:0033554;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane protein complex#GO:0098796;endoplasmic reticulum protein-containing complex#GO:0140534;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 CIOIN|Ensembl=ENSCING00000003277.3|UniProtKB=F6ZJ12 F6ZJ12 LOC100178669 PTHR11132:SF515 SOLUTE CARRIER FAMILY 35 SOLUTE CARRIER FAMILY 35 MEMBER D3 secondary active transmembrane transporter activity#GO:0015291;antiporter activity#GO:0015297;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 localization#GO:0051179;cellular process#GO:0009987;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000001383.3|UniProtKB=F6S8Y1 F6S8Y1 LOC100184381 PTHR10996:SF257 2-HYDROXYACID DEHYDROGENASE-RELATED GLYOXYLATE REDUCTASE 1 oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000007520.3|UniProtKB=F6UJ17 F6UJ17 PTHR23172:SF19 AUXILIN/CYCLIN G-ASSOCIATED KINASE-RELATED J DOMAIN-CONTAINING PROTEIN protein binding#GO:0005515;clathrin binding#GO:0030276;binding#GO:0005488 localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular component disassembly#GO:0022411;protein-containing complex disassembly#GO:0032984;establishment of localization#GO:0051234;clathrin-dependent endocytosis#GO:0072583;protein-containing complex organization#GO:0043933;transport#GO:0006810;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;receptor-mediated endocytosis#GO:0006898;protein depolymerization#GO:0051261;cellular component organization#GO:0016043;cellular process#GO:0009987;import into cell#GO:0098657 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150 CIOIN|Ensembl=ENSCING00000000567.3|UniProtKB=F6Q3Y2 F6Q3Y2 PTHR13267:SF3 ZINC FINGER PROTEIN 277 ZINC FINGER PROTEIN 277 zinc finger transcription factor#PC00244 CIOIN|Ensembl=ENSCING00000021785.1|UniProtKB=H2XKF6 H2XKF6 LOC100175860 PTHR31909:SF2 CHROMOSOME 20 ORF85 FAMILY MEMBER RIKEN CDNA 2410004P03 GENE CIOIN|Ensembl=ENSCING00000013294.2|UniProtKB=F6Z5K9 F6Z5K9 PTHR36978:SF4 P-LOOP CONTAINING NUCLEOTIDE TRIPHOSPHATE HYDROLASE P-LOOP CONTAINING NUCLEOSIDE TRIPHOSPHATE HYDROLASE PROTEIN metabolite interconversion enzyme#PC00262;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000008760.3|UniProtKB=F6T072 F6T072 LOC100184927 PTHR45742:SF8 COMPLEMENT COMPONENT C6 FLOCCULATION PROTEIN FLO11 complement component#PC00078 CIOIN|Ensembl=ENSCING00000015272.2|UniProtKB=F6TYE2 F6TYE2 LOC100101826 PTHR24033:SF193 EGF-LIKE DOMAIN-CONTAINING PROTEIN NETRIN-G1-RELATED Axon guidance mediated by netrin#P00009>Netrin#P00357;Axon guidance mediated by Slit/Robo#P00008>Netrin#P00344 CIOIN|Ensembl=ENSCING00000022648.1|UniProtKB=H2XME7 H2XME7 PTHR24373:SF370 SLIT RELATED LEUCINE-RICH REPEAT NEURONAL PROTEIN FISH-LIPS, ISOFORM E external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 transmembrane signal receptor#PC00197 CIOIN|Ensembl=ENSCING00000003600.3|UniProtKB=F6UYC8 F6UYC8 PTHR24229:SF112 NEUROPEPTIDES RECEPTOR CHEMOKINE-LIKE RECEPTOR 1 neuropeptide binding#GO:0042923;signaling receptor activity#GO:0038023;binding#GO:0005488;peptide binding#GO:0042277;amide binding#GO:0033218;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;neuropeptide signaling pathway#GO:0007218;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;neuron projection#GO:0043005;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 CIOIN|Ensembl=ENSCING00000011409.2|UniProtKB=F7AXP7 F7AXP7 PTHR14963:SF7 RHO GTPASE ACTIVATING PROTEIN 18,19-RELATED RHO GTPASE-ACTIVATING PROTEIN 19 GTPase-activating protein#PC00257 CIOIN|Ensembl=ENSCING00000018419.1|UniProtKB=F6YG34 F6YG34 PTHR11482:SF6 ARGININE/DIAMINOPIMELATE/ORNITHINE DECARBOXYLASE ORNITHINE DECARBOXYLASE 1-RELATED lyase activity#GO:0016829;carboxy-lyase activity#GO:0016831;carbon-carbon lyase activity#GO:0016830;catalytic activity#GO:0003824 amine metabolic process#GO:0009308;oxoacid metabolic process#GO:0043436;biogenic amine metabolic process#GO:0006576;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;polyamine metabolic process#GO:0006595;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;alpha-amino acid metabolic process#GO:1901605;polyamine biosynthetic process#GO:0006596;carboxylic acid metabolic process#GO:0019752;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 decarboxylase#PC00089 Ornithine degradation#P02758>Ornithine decarboxylase#P03053 CIOIN|Ensembl=ENSCING00000009861.3|UniProtKB=F6XFW8 F6XFW8 LOC100180650 PTHR23503:SF8 SOLUTE CARRIER FAMILY 2 FACILITATED GLUCOSE TRANSPORTER PROTEIN 1 transmembrane transporter activity#GO:0022857;sugar transmembrane transporter activity#GO:0051119;transporter activity#GO:0005215;carbohydrate transmembrane transporter activity#GO:0015144 localization#GO:0051179;organic substance transport#GO:0071702;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810;cellular process#GO:0009987;carbohydrate transmembrane transport#GO:0034219;carbohydrate transport#GO:0008643 cellular anatomical entity#GO:0110165;membrane#GO:0016020 secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000017302.2|UniProtKB=F6PP44 F6PP44 LOC100178673 PTHR11627:SF80 FRUCTOSE-BISPHOSPHATE ALDOLASE FRUCTOSE-BISPHOSPHATE ALDOLASE-RELATED aldolase#PC00044;lyase#PC00144 Glycolysis#P00024>Aldolase#P00679;Fructose galactose metabolism#P02744>Fructose bisphosphate aldolase#P02959 CIOIN|Ensembl=ENSCING00000013743.2|UniProtKB=F6RQN0 F6RQN0 PTHR12011:SF471 ADHESION G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 2 PROFILE 2 DOMAIN-CONTAINING PROTEIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 CIOIN|Ensembl=ENSCING00000013124.2|UniProtKB=F7BMY3 F7BMY3 PTHR12745:SF6 SUPPRESSION OF TUMORIGENICITY 7 PROTEIN ST7 HOMOLOG CIOIN|Ensembl=ENSCING00000007810.3|UniProtKB=F6WHP2 F6WHP2 LOC100176509 PTHR46533:SF1 ZINC FINGER MYND DOMAIN-CONTAINING PROTEIN 12 ZINC FINGER MYND DOMAIN-CONTAINING PROTEIN 12 CIOIN|Ensembl=ENSCING00000002378.3|UniProtKB=F6QZF6 F6QZF6 LOC100177554 PTHR46505:SF1 OXIDOREDUCTASE NAD-BINDING DOMAIN-CONTAINING PROTEIN 1 OXIDOREDUCTASE NAD-BINDING DOMAIN-CONTAINING PROTEIN 1 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000021453.1|UniProtKB=H2XKA0 H2XKA0 PTHR22803:SF155 MANNOSE, PHOSPHOLIPASE, LECTIN RECEPTOR RELATED ACCESSORY GLAND PROTEIN ACP29AB-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 membrane trafficking regulatory protein#PC00151 CIOIN|Ensembl=ENSCING00000025226.1|UniProtKB=Q8HIM9 Q8HIM9 COI PTHR10422:SF18 CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 1 inorganic molecular entity transmembrane transporter activity#GO:0015318;transmembrane transporter activity#GO:0022857;primary active transmembrane transporter activity#GO:0015399;electron transfer activity#GO:0009055;catalytic activity#GO:0003824;proton transmembrane transporter activity#GO:0015078;active monoatomic ion transmembrane transporter activity#GO:0022853;monoatomic cation transmembrane transporter activity#GO:0008324;oxidoreductase activity#GO:0016491;monoatomic ion transmembrane transporter activity#GO:0015075;inorganic cation transmembrane transporter activity#GO:0022890;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 aerobic respiration#GO:0009060;cellular respiration#GO:0045333;transmembrane transport#GO:0055085;proton transmembrane transport#GO:1902600;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;generation of precursor metabolites and energy#GO:0006091;electron transport chain#GO:0022900;cellular metabolic process#GO:0044237;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;energy derivation by oxidation of organic compounds#GO:0015980;localization#GO:0051179;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;respiratory electron transport chain#GO:0022904;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;metabolic process#GO:0008152 oxidase#PC00175;oxidoreductase#PC00176 ATP synthesis#P02721>Cytochrome oxidase aa3#P02793 CIOIN|Ensembl=ENSCING00000003349.3|UniProtKB=F6TDS0 F6TDS0 PTHR14390:SF2 G PATCH DOMAIN CONTAINING PROTEIN 3 G PATCH DOMAIN-CONTAINING PROTEIN 3 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;positive regulation of cellular metabolic process#GO:0031325;regulation of RNA biosynthetic process#GO:2001141;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of biosynthetic process#GO:0009889;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;biological regulation#GO:0065007;positive regulation of RNA metabolic process#GO:0051254;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 CIOIN|Ensembl=ENSCING00000023519.1|UniProtKB=H2XPY7 H2XPY7 PTHR24302:SF15 CYTOCHROME P450 FAMILY 3 FATTY-ACID PEROXYGENASE oxygenase#PC00177;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000003436.3|UniProtKB=F6XKW6 F6XKW6 PTHR46541:SF1 ZINC FINGER PROTEIN AEBP2 ZINC FINGER PROTEIN AEBP2 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;histone methyltransferase complex#GO:0035097;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;methyltransferase complex#GO:0034708;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;PcG protein complex#GO:0031519;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 CIOIN|Ensembl=ENSCING00000003440.3|UniProtKB=L7N0R4 L7N0R4 PTHR43975:SF2 ZGC:101858 EG:BACR7A4.14 PROTEIN-RELATED CIOIN|Ensembl=ENSCING00000007820.3|UniProtKB=F6WH38 F6WH38 PTHR23113:SF356 GUANINE NUCLEOTIDE EXCHANGE FACTOR FI05912P-RELATED nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;small GTPase-mediated signal transduction#GO:0007264;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;Ras protein signal transduction#GO:0007265;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 CIOIN|Ensembl=ENSCING00000018148.1|UniProtKB=H2XT62 H2XT62 PTHR46306:SF1 BTB/POZ DOMAIN-CONTAINING PROTEIN 9 BTB_POZ DOMAIN-CONTAINING PROTEIN 9 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000007666.3|UniProtKB=F6T7K5 F6T7K5 LOC100184676 PTHR10697:SF1 MAMMALIAN EPENDYMIN-RELATED PROTEIN 1 MAMMALIAN EPENDYMIN-RELATED PROTEIN 1 cytoplasm#GO:0005737;lysosome#GO:0005764;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;lytic vacuole#GO:0000323;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000023504.1|UniProtKB=H2Y0T0 H2Y0T0 PTHR13555:SF25 C2H2 ZINC FINGER CGI-62-RELATED ZINC FINGER C2HC DOMAIN-CONTAINING PROTEIN 1A C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 CIOIN|Ensembl=ENSCING00000023249.1|UniProtKB=H2XUP0 H2XUP0 PTHR23282:SF149 APICAL ENDOSOMAL GLYCOPROTEIN PRECURSOR. MAM DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000006262.3|UniProtKB=F6VQ32 F6VQ32 PTHR11571:SF150 GLUTATHIONE S-TRANSFERASE GLUTATHIONE S-TRANSFERASE glutathione transferase activity#GO:0004364;transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824 sulfur compound metabolic process#GO:0006790;nitrogen compound metabolic process#GO:0006807;peptide metabolic process#GO:0006518;cellular modified amino acid metabolic process#GO:0006575;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular process#GO:0009987;glutathione metabolic process#GO:0006749;amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000005681.3|UniProtKB=F6XCZ8 F6XCZ8 LOC100176736 PTHR11588:SF501 TUBULIN TUBULIN ALPHA CHAIN carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;structural molecule activity#GO:0005198;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167;structural constituent of cytoskeleton#GO:0005200 cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;microtubule-based process#GO:0007017;organelle organization#GO:0006996;microtubule cytoskeleton organization#GO:0000226;cytoskeleton organization#GO:0007010;cell cycle#GO:0007049;cellular component organization#GO:0016043;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622 tubulin#PC00228;microtubule or microtubule-binding cytoskeletal protein#PC00157 CIOIN|Ensembl=ENSCING00000004592.3|UniProtKB=F6PSB3 F6PSB3 PTHR12002:SF116 CLAUDIN CLAUDIN-11-LIKE cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cell-cell junction organization#GO:0045216;cellular component biogenesis#GO:0044085;cell-cell junction assembly#GO:0007043;cell junction organization#GO:0034330;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;cell adhesion#GO:0007155;cellular process#GO:0009987 tight junction#GO:0070160;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cell junction#GO:0030054;bicellular tight junction#GO:0005923;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;apical junction complex#GO:0043296;plasma membrane#GO:0005886 cell junction protein#PC00070;tight junction#PC00214 CIOIN|Ensembl=ENSCING00000002195.3|UniProtKB=F6S593 F6S593 PTHR47765:SF2 3'-5' EXONUCLEASE DOMAIN-CONTAINING PROTEIN EXONUCLEASE MUT-7 HOMOLOG CIOIN|Ensembl=ENSCING00000002838.3|UniProtKB=F6WD51 F6WD51 atf3 PTHR23351:SF59 FOS TRANSCRIPTION FACTOR-RELATED CYCLIC AMP-DEPENDENT TRANSCRIPTION FACTOR ATF-3-LIKE sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;basic leucine zipper transcription factor#PC00056 CIOIN|Ensembl=ENSCING00000003579.3|UniProtKB=F6ZZS3 F6ZZS3 LOC100178405 PTHR15663:SF4 COMM DOMAIN-CONTAINING PROTEIN 9 COMM DOMAIN-CONTAINING PROTEIN 9 CIOIN|Ensembl=ENSCING00000014908.2|UniProtKB=F6Y805 F6Y805 PTHR24246:SF27 OLFACTORY RECEPTOR AND ADENOSINE RECEPTOR ADENOSINE RECEPTOR, ISOFORM A G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711 CIOIN|Ensembl=ENSCING00000007941.3|UniProtKB=F6ZRN6 F6ZRN6 LOC100176709 PTHR21780:SF0 TRANSMEMBRANE PROTEIN 209 TRANSMEMBRANE PROTEIN 209 cellular anatomical entity#GO:0110165;membrane#GO:0016020 CIOIN|Ensembl=ENSCING00000013397.2|UniProtKB=F6VRW5 F6VRW5 LOC100175021 PTHR35378:SF1 UNNAMED PRODUCT C2H2-TYPE DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000008984.3|UniProtKB=F6PKT6 F6PKT6 PTHR23081:SF36 RNA POLYMERASE II CTD PHOSPHATASE RNA POLYMERASE II SUBUNIT A C-TERMINAL DOMAIN PHOSPHATASE hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;protein serine/threonine phosphatase activity#GO:0004722;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 protein phosphatase#PC00195;protein modifying enzyme#PC00260 General transcription regulation#P00023>TFIIF#P00665;Transcription regulation by bZIP transcription factor#P00055>TFIIF#P01394 CIOIN|Ensembl=ENSCING00000001067.3|UniProtKB=F7B0U3 F7B0U3 LOC100183086 PTHR10656:SF69 CELL FATE DETERMINING PROTEIN MAB21-RELATED MAB-21-LIKE HHH_H2TH-LIKE DOMAIN-CONTAINING PROTEIN transferase#PC00220;nucleotidyltransferase#PC00174;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000013856.2|UniProtKB=F6QGK7 F6QGK7 LOC100178432 PTHR35354:SF1 RGD1561648 RGD1561648 CIOIN|Ensembl=ENSCING00000007401.3|UniProtKB=F6RZH2 F6RZH2 PTHR10574:SF419 NETRIN/LAMININ-RELATED LAMININ SUBUNIT ALPHA-3-RELATED neuron projection guidance#GO:0097485;cellular component biogenesis#GO:0044085;neurogenesis#GO:0022008;cell projection organization#GO:0030030;animal organ development#GO:0048513;developmental process#GO:0032502;substrate adhesion-dependent cell spreading#GO:0034446;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;extracellular matrix organization#GO:0030198;cellular anatomical entity morphogenesis#GO:0032989;system development#GO:0048731;cell differentiation#GO:0030154;axon guidance#GO:0007411;anatomical structure morphogenesis#GO:0009653;external encapsulating structure organization#GO:0045229;neuron differentiation#GO:0030182;axonogenesis#GO:0007409;plasma membrane bounded cell projection morphogenesis#GO:0120039;cellular developmental process#GO:0048869;cellular component assembly#GO:0022607;multicellular organism development#GO:0007275;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;cell adhesion#GO:0007155;cell motility#GO:0048870;cell-substrate adhesion#GO:0031589;cellular process#GO:0009987;tissue development#GO:0009888;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;extracellular structure organization#GO:0043062;cell morphogenesis involved in neuron differentiation#GO:0048667;anatomical structure development#GO:0048856;animal organ morphogenesis#GO:0009887;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;cell migration#GO:0016477 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;basement membrane#GO:0005604 extracellular matrix protein#PC00102 CIOIN|Ensembl=ENSCING00000017037.2|UniProtKB=F6XQP8 F6XQP8 LOC100179954 PTHR13680:SF5 CDGSH IRON-SULFUR DOMAIN-CONTAINING PROTEIN 1 CDGSH IRON-SULFUR DOMAIN-CONTAINING PROTEIN 1 small molecule binding#GO:0036094;binding#GO:0005488;iron-sulfur cluster binding#GO:0051536 envelope#GO:0031975;bounding membrane of organelle#GO:0098588;mitochondrial membrane#GO:0031966;intracellular membrane-bounded organelle#GO:0043231;mitochondrial outer membrane#GO:0005741;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867 CIOIN|Ensembl=ENSCING00000016648.2|UniProtKB=F6PMX0 F6PMX0 LOC100175357 PTHR14002:SF54 ENDOGLIN/TGF-BETA RECEPTOR TYPE III ZONA PELLUCIDA SPERM-BINDING PROTEIN 2 transmembrane signal receptor#PC00197 CIOIN|Ensembl=ENSCING00000009751.3|UniProtKB=F7ABV6 F7ABV6 PTHR11709:SF504 MULTI-COPPER OXIDASE PLASTOCYANIN-LIKE DOMAIN-CONTAINING PROTEIN catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 localization#GO:0051179;metal ion transport#GO:0030001;establishment of localization#GO:0051234;transport#GO:0006810;monoatomic cation transport#GO:0006812;iron ion transport#GO:0006826;transition metal ion transport#GO:0000041;monoatomic ion transport#GO:0006811 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 oxidase#PC00175;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000004604.3|UniProtKB=F6W3H6 F6W3H6 PTHR16146:SF46 INTELECTIN INTELECTIN-1A-RELATED CIOIN|Ensembl=ENSCING00000007940.3|UniProtKB=F6ZRP3 F6ZRP3 PTHR24050:SF27 PA14 DOMAIN-CONTAINING PROTEIN FIBRILLIN-1 CIOIN|Ensembl=ENSCING00000004327.3|UniProtKB=F7BND4 F7BND4 PTHR23025:SF3 TRIACYLGLYCEROL LIPASE HORMONE-SENSITIVE LIPASE hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;catalytic activity#GO:0003824;triglyceride lipase activity#GO:0004806 lipid metabolic process#GO:0006629;triglyceride metabolic process#GO:0006641;neutral lipid catabolic process#GO:0046461;cellular metabolic process#GO:0044237;glycerolipid catabolic process#GO:0046503;triglyceride catabolic process#GO:0019433;lipid catabolic process#GO:0016042;cellular process#GO:0009987;acylglycerol metabolic process#GO:0006639;primary metabolic process#GO:0044238;acylglycerol catabolic process#GO:0046464;neutral lipid metabolic process#GO:0006638;glycerolipid metabolic process#GO:0046486;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;cellular lipid metabolic process#GO:0044255;cellular lipid catabolic process#GO:0044242;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 lipase#PC00143 Triacylglycerol metabolism#P02782>Triacylglycerol lipase#P03205 CIOIN|Ensembl=ENSCING00000022124.1|UniProtKB=H2XP81 H2XP81 PTHR45672:SF11 PROTEIN DISULFIDE-ISOMERASE C17H9.14C-RELATED PROTEIN DISULFIDE-ISOMERASE C17H9.14C isomerase activity#GO:0016853;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;protein disulfide isomerase activity#GO:0003756 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein folding#GO:0006457;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chaperone#PC00072 CIOIN|Ensembl=ENSCING00000023663.1|UniProtKB=H2XY41 H2XY41 PTHR14340:SF9 MICROFIBRIL-ASSOCIATED GLYCOPROTEIN 3 FIBRONECTIN TYPE-III DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000002828.3|UniProtKB=F6WYU9 F6WYU9 PIF1 PTHR23274:SF11 DNA HELICASE-RELATED ATP-DEPENDENT DNA HELICASE PIF1 DNA metabolism protein#PC00009;DNA helicase#PC00011 CIOIN|Ensembl=ENSCING00000003068.3|UniProtKB=Q1RL46 Q1RL46 Ci-ZF(C2H2)-149 PTHR13555:SF68 C2H2 ZINC FINGER CGI-62-RELATED ZINC FINGER PROTEIN 474 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 CIOIN|Ensembl=ENSCING00000007872.3|UniProtKB=F6TGZ0 F6TGZ0 PTHR24134:SF9 ANKYRIN REPEAT-CONTAINING PROTEIN DDB_G0279043 ANKYRIN REPEAT AND SOCS BOX PROTEIN 8 CIOIN|Ensembl=ENSCING00000008860.3|UniProtKB=F6R356 F6R356 PTHR11629:SF63 VACUOLAR PROTON ATPASES V-TYPE PROTON ATPASE SUBUNIT A enzyme binding#GO:0019899;protein binding#GO:0005515;binding#GO:0005488 regulation of intracellular pH#GO:0051453;regulation of pH#GO:0006885;regulation of biological quality#GO:0065008;intracellular monoatomic cation homeostasis#GO:0030003;biological regulation#GO:0065007;intracellular pH reduction#GO:0051452;homeostatic process#GO:0042592;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic ion homeostasis#GO:0006873;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;vacuolar acidification#GO:0007035;regulation of cellular pH#GO:0030641;intracellular chemical homeostasis#GO:0055082;monoatomic ion homeostasis#GO:0050801 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;vacuolar membrane#GO:0005774;ATPase complex#GO:1904949;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;proton-transporting two-sector ATPase complex#GO:0016469;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227 ATP synthase#PC00002;primary active transporter#PC00068;transporter#PC00227 CIOIN|Ensembl=ENSCING00000001505.3|UniProtKB=F6SVI8 F6SVI8 LOC100185903 PTHR21705:SF12 RAI16 PROTEIN-RELATED FHF COMPLEX SUBUNIT HOOK-INTERACTING PROTEIN C-TERMINAL DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000017910.1|UniProtKB=H2Y0V5 H2Y0V5 PTHR11929:SF145 ALPHA- 1,3 -FUCOSYLTRANSFERASE ALPHA-(1,3)-FUCOSYLTRANSFERASE FUT-1 transferase activity#GO:0016740;fucosyltransferase activity#GO:0008417;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 glycosylation#GO:0070085;metabolic process#GO:0008152 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000009208.3|UniProtKB=F6WNB2 F6WNB2 PTHR45797:SF1 RAD54-LIKE HELICASE ARIP4 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000020482.1|UniProtKB=H2XQX6 H2XQX6 LOC100187279 PTHR11588:SF7 TUBULIN TUBULIN GAMMA CHAIN carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;structural molecule activity#GO:0005198;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167;structural constituent of cytoskeleton#GO:0005200 cellular component biogenesis#GO:0044085;mitotic spindle organization#GO:0007052;nuclear division#GO:0000280;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;protein-containing complex assembly#GO:0065003;microtubule cytoskeleton organization involved in mitosis#GO:1902850;microtubule polymerization or depolymerization#GO:0031109;mitotic cell cycle process#GO:1903047;chromosome segregation#GO:0007059;mitotic cell cycle#GO:0000278;microtubule polymerization#GO:0046785;meiotic cell cycle process#GO:1903046;supramolecular fiber organization#GO:0097435;reproductive process#GO:0022414;cytoskeleton organization#GO:0007010;mitotic nuclear division#GO:0140014;mitotic sister chromatid segregation#GO:0000070;spindle organization#GO:0007051;cellular component assembly#GO:0022607;nuclear chromosome segregation#GO:0098813;sister chromatid segregation#GO:0000819;meiotic cell cycle#GO:0051321;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;reproduction#GO:0000003;microtubule-based process#GO:0007017;protein-containing complex organization#GO:0043933;chromosome organization#GO:0051276;organelle organization#GO:0006996;sexual reproduction#GO:0019953;protein polymerization#GO:0051258;cell cycle#GO:0007049;organelle fission#GO:0048285;microtubule nucleation#GO:0007020 supramolecular complex#GO:0099080;microtubule organizing center#GO:0005815;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;supramolecular fiber#GO:0099512;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;centrosome#GO:0005813;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;spindle#GO:0005819;microtubule#GO:0005874 tubulin#PC00228;microtubule or microtubule-binding cytoskeletal protein#PC00157 CIOIN|Ensembl=ENSCING00000021718.1|UniProtKB=H2Y0L3 H2Y0L3 PTHR15977:SF15 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 46 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 46 CIOIN|Ensembl=ENSCING00000008698.3|UniProtKB=A1XDA5 A1XDA5 stip PTHR23329:SF1 TUFTELIN-INTERACTING PROTEIN 11-RELATED TUFTELIN-INTERACTING PROTEIN 11 cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;RNA processing#GO:0006396;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;mRNA metabolic process#GO:0016071;cellular component disassembly#GO:0022411;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;protein-containing complex disassembly#GO:0032984;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;protein-containing complex organization#GO:0043933;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;protein-RNA complex organization#GO:0071826;RNA splicing, via transesterification reactions#GO:0000375 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;U2-type spliceosomal complex#GO:0005684;cellular anatomical entity#GO:0110165;organelle#GO:0043226;post-mRNA release spliceosomal complex#GO:0071014;spliceosomal complex#GO:0005681;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA splicing factor#PC00148;RNA processing factor#PC00147;RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000015157.2|UniProtKB=F6XZ04 F6XZ04 PTHR23064:SF72 TROPONIN TROPONIN C, SKELETAL MUSCLE cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 CIOIN|Ensembl=ENSCING00000021708.1|UniProtKB=F6V580 F6V580 LOC100185392 PTHR14359:SF6 HOMO-OLIGOMERIC FLAVIN CONTAINING CYS DECARBOXYLASE FAMILY PHOSPHOPANTOTHENOYLCYSTEINE DECARBOXYLASE carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;carboxy-lyase activity#GO:0016831;carbon-carbon lyase activity#GO:0016830;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;lyase activity#GO:0016829;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;anion binding#GO:0043168 cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622 decarboxylase#PC00089 Coenzyme A biosynthesis#P02736>Pantothenate cysteine ligase#P02882;Coenzyme A biosynthesis#P02736>Pantothenoylcysteine decarboxylase#P02883 CIOIN|Ensembl=ENSCING00000001943.3|UniProtKB=A0A1W3JJB9 A0A1W3JJB9 LOC100185085 PTHR11947:SF3 PYRUVATE DEHYDROGENASE KINASE [PYRUVATE DEHYDROGENASE (ACETYL-TRANSFERRING)] KINASE, MITOCHONDRIAL transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;biological regulation#GO:0065007;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;regulation of metabolic process#GO:0019222;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000008347.3|UniProtKB=F7AKG2 F7AKG2 PTHR10169:SF38 DNA TOPOISOMERASE/GYRASE DNA TOPOISOMERASE 2 cellular aromatic compound metabolic process#GO:0006725;nuclear division#GO:0000280;cell cycle process#GO:0022402;nucleobase-containing compound metabolic process#GO:0006139;chromosome segregation#GO:0007059;reciprocal homologous recombination#GO:0140527;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;meiotic cell cycle process#GO:1903046;meiosis I cell cycle process#GO:0061982;reciprocal meiotic recombination#GO:0007131;reproductive process#GO:0022414;meiosis I#GO:0007127;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;nuclear chromosome segregation#GO:0098813;sister chromatid segregation#GO:0000819;macromolecule metabolic process#GO:0043170;meiotic cell cycle#GO:0051321;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;DNA recombination#GO:0006310;resolution of meiotic recombination intermediates#GO:0000712;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;reproduction#GO:0000003;meiotic nuclear division#GO:0140013;organelle organization#GO:0006996;chromosome organization#GO:0051276;sexual reproduction#GO:0019953;cell cycle#GO:0007049;organelle fission#GO:0048285;homologous recombination#GO:0035825;DNA metabolic process#GO:0006259 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA metabolism protein#PC00009 DNA replication#P00017>Top#P00530;DNA replication#P00017>DNA Topisomerase#P00536 CIOIN|Ensembl=ENSCING00000021413.1|UniProtKB=H2XVW4 H2XVW4 PTHR11777:SF9 ALANYL-TRNA SYNTHETASE ALANINE--TRNA LIGASE, CYTOPLASMIC catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;ligase activity#GO:0016874;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;peptide biosynthetic process#GO:0043043;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 aminoacyl-tRNA synthetase#PC00047;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000006704.3|UniProtKB=F7ARH4 F7ARH4 PTHR46513:SF44 VITELLOGENIN RECEPTOR-LIKE PROTEIN-RELATED-RELATED LDL RECEPTOR RELATED PROTEIN 4 transmembrane signal receptor#PC00197 CIOIN|Ensembl=ENSCING00000007825.3|UniProtKB=F6WTE3 F6WTE3 PTHR45633:SF3 60 KDA HEAT SHOCK PROTEIN, MITOCHONDRIAL 60 KDA HEAT SHOCK PROTEIN, MITOCHONDRIAL macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein folding#GO:0006457;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 CIOIN|Ensembl=ENSCING00000012004.2|UniProtKB=F6RWK5 F6RWK5 PTHR11814:SF105 SULFATE TRANSPORTER STAS DOMAIN-CONTAINING PROTEIN inorganic molecular entity transmembrane transporter activity#GO:0015318;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;organic acid transmembrane transporter activity#GO:0005342;chloride transmembrane transporter activity#GO:0015108;monoatomic anion transmembrane transporter activity#GO:0008509;organic anion transmembrane transporter activity#GO:0008514;inorganic anion transmembrane transporter activity#GO:0015103;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 transporter#PC00227 CIOIN|Ensembl=ENSCING00000018160.1|UniProtKB=H2XR23 H2XR23 LOC100177996 PTHR23050:SF518 CALCIUM BINDING PROTEIN AT16150P-RELATED cation binding#GO:0043169;small molecule binding#GO:0036094;molecular function regulator activity#GO:0098772;binding#GO:0005488;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;enzyme regulator activity#GO:0030234 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 calmodulin-related#PC00061 B cell activation#P00010>Calmodulin#P00375;Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Calmodulin#P00755;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Phosphorylase b kinase#P00716;T cell activation#P00053>Calmodulin#P01305 CIOIN|Ensembl=ENSCING00000004493.3|UniProtKB=F6TFA5 F6TFA5 LOC100176079 PTHR23320:SF158 MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MS4A -RELATED CREB-BINDING PROTEIN-LIKE ISOFORM X1 transporter#PC00227 CIOIN|Ensembl=ENSCING00000004825.2|UniProtKB=F6R939 F6R939 PTHR14605:SF1 CHST5 PROTEIN TRANSMEMBRANE PROTEIN 231 cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cell projection organization#GO:0030030;regulation of localization#GO:0032879;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of cellular localization#GO:0060341;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031;organelle assembly#GO:0070925;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;plasma membrane bounded cell projection assembly#GO:0120031;regulation of protein localization#GO:0032880 bounding membrane of organelle#GO:0098588;ciliary membrane#GO:0060170;membrane-bounded organelle#GO:0043227;plasma membrane region#GO:0098590;organelle membrane#GO:0031090;cell projection membrane#GO:0031253;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;cilium#GO:0005929;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;ciliary transition zone#GO:0035869;plasma membrane#GO:0005886 CIOIN|Ensembl=ENSCING00000002674.3|UniProtKB=F6XQD4 F6XQD4 LOC100180400 PTHR10073:SF52 DNA MISMATCH REPAIR PROTEIN MLH, PMS, MUTL MISMATCH REPAIR ENDONUCLEASE PMS2 pyrophosphatase activity#GO:0016462;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ATP hydrolysis activity#GO:0016887;ribonucleoside triphosphate phosphatase activity#GO:0017111 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;mismatch repair#GO:0006298;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;DNA damage response#GO:0006974;response to stress#GO:0006950;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular response to stress#GO:0033554;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA metabolism protein#PC00009 CIOIN|Ensembl=ENSCING00000020143.1|UniProtKB=H2XW11 H2XW11 LOC100187194 PTHR31885:SF6 GH04784P GH04784P hydrolase activity#GO:0016787;catalytic activity#GO:0003824 cellular anatomical entity#GO:0110165;membrane#GO:0016020 CIOIN|Ensembl=ENSCING00000003778.3|UniProtKB=F6TIT7 F6TIT7 LOC100185034 PTHR20843:SF0 STERILE ALPHA MOTIF DOMAIN CONTAINING PROTEIN 10 PROTEIN AVEUGLE regulation of biological process#GO:0050789;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;cytoplasmic side of plasma membrane#GO:0009898;plasma membrane#GO:0005886 CIOIN|Ensembl=ENSCING00000005045.3|UniProtKB=F7A4Y2 F7A4Y2 PTHR24353:SF147 CYCLIC NUCLEOTIDE-DEPENDENT PROTEIN KINASE CGMP-DEPENDENT SERINE_THREONIN PROTEIN KINASE-RELATED non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Endothelin signaling pathway#P00019>PKG#P00567 CIOIN|Ensembl=ENSCING00000003355.3|UniProtKB=F6S0S0 F6S0S0 LOC100177315 PTHR12303:SF6 CARNOSINE N-METHYLTRANSFERASE CARNOSINE N-METHYLTRANSFERASE methyltransferase activity#GO:0008168;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757 CIOIN|Ensembl=ENSCING00000002879.3|UniProtKB=F6T0T4 F6T0T4 PTHR24039:SF58 FIBRILLIN-RELATED EGF-LIKE DOMAIN-CONTAINING PROTEIN extracellular matrix structural protein#PC00103 CIOIN|Ensembl=ENSCING00000023666.1|UniProtKB=H2XZZ2 H2XZZ2 PTHR21008:SF0 S-ADENOSYLMETHIONINE SENSOR UPSTREAM OF MTORC1-RELATED S-ADENOSYLMETHIONINE SENSOR UPSTREAM OF MTORC1 regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;regulation of TORC1 signaling#GO:1903432;negative regulation of response to stimulus#GO:0048585;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;negative regulation of TOR signaling#GO:0032007;regulation of intracellular signal transduction#GO:1902531;regulation of TOR signaling#GO:0032006;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of TORC1 signaling#GO:1904262;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648 CIOIN|Ensembl=ENSCING00000002061.3|UniProtKB=F6SU68 F6SU68 LOC100186791 PTHR11955:SF156 FATTY ACID BINDING PROTEIN LIPOCALIN_CYTOSOLIC FATTY-ACID BINDING DOMAIN-CONTAINING PROTEIN fatty acid binding#GO:0005504;small molecule binding#GO:0036094;binding#GO:0005488;carboxylic acid binding#GO:0031406;lipid binding#GO:0008289;ion binding#GO:0043167;organic acid binding#GO:0043177;anion binding#GO:0043168 localization#GO:0051179;monocarboxylic acid transport#GO:0015718;organic substance transport#GO:0071702;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;organic anion transport#GO:0015711;fatty acid transport#GO:0015908;organic acid transport#GO:0015849;transport#GO:0006810;carboxylic acid transport#GO:0046942;lipid localization#GO:0010876;lipid transport#GO:0006869 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transfer/carrier protein#PC00219 CIOIN|Ensembl=ENSCING00000021619.1|UniProtKB=H2XKU4 H2XKU4 PTHR11256:SF50 BCL-2 RELATED APOPTOSIS REGULATOR CED-9 protein binding#GO:0005515;binding#GO:0005488 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0043280;intrinsic apoptotic signaling pathway in response to DNA damage#GO:0008630;signal transduction#GO:0007165;positive regulation of cysteine-type endopeptidase activity#GO:2001056;regulation of protein metabolic process#GO:0051246;apoptotic mitochondrial changes#GO:0008637;regulation of cysteine-type endopeptidase activity#GO:2000116;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;positive regulation of proteolysis#GO:0045862;regulation of biological process#GO:0050789;activation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0006919;DNA damage response#GO:0006974;positive regulation of metabolic process#GO:0009893;regulation of molecular function#GO:0065009;apoptotic process#GO:0006915;cell death#GO:0008219;regulation of hydrolase activity#GO:0051336;mitochondrion organization#GO:0007005;intracellular signal transduction#GO:0035556;positive regulation of biological process#GO:0048518;positive regulation of peptidase activity#GO:0010952;signaling#GO:0023052;regulation of proteolysis#GO:0030162;cellular response to stimulus#GO:0051716;positive regulation of catalytic activity#GO:0043085;programmed cell death#GO:0012501;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of hydrolase activity#GO:0051345;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;intrinsic apoptotic signaling pathway#GO:0097193;apoptotic signaling pathway#GO:0097190;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;response to stress#GO:0006950;extrinsic apoptotic signaling pathway#GO:0097191;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of endopeptidase activity#GO:0052548;regulation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0043281;regulation of peptidase activity#GO:0052547;release of cytochrome c from mitochondria#GO:0001836;cellular response to stress#GO:0033554;positive regulation of endopeptidase activity#GO:0010950;regulation of metabolic process#GO:0019222 bounding membrane of organelle#GO:0098588;envelope#GO:0031975;mitochondrial membrane#GO:0031966;mitochondrial outer membrane#GO:0005741;intracellular membrane-bounded organelle#GO:0043231;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867 CIOIN|Ensembl=ENSCING00000013635.2|UniProtKB=F6UCI3 F6UCI3 PTHR24039:SF58 FIBRILLIN-RELATED EGF-LIKE DOMAIN-CONTAINING PROTEIN extracellular matrix structural protein#PC00103 CIOIN|Ensembl=ENSCING00000023026.1|UniProtKB=H2XQC1 H2XQC1 PTHR10555:SF170 SORTING NEXIN FI18122P1 lipid binding#GO:0008289;phosphatidylinositol binding#GO:0035091;phospholipid binding#GO:0005543;binding#GO:0005488 cytoplasm#GO:0005737;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000020358.1|UniProtKB=H2XX66 H2XX66 PTHR23354:SF62 NUCLEOLAR PROTEIN 7/ESTROGEN RECEPTOR COACTIVATOR-RELATED MUSTARD, ISOFORM V CIOIN|Ensembl=ENSCING00000009959.3|UniProtKB=F6R508 F6R508 LOC100183902 PTHR31022:SF4 CENTRIOLE, CILIA AND SPINDLE-ASSOCIATED PROTEIN CENTRIOLE, CILIA AND SPINDLE-ASSOCIATED PROTEIN cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 regulation of biological process#GO:0050789;regulation of microtubule-based process#GO:0032886;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component biogenesis#GO:0044087;regulation of cellular process#GO:0050794;regulation of organelle organization#GO:0033043;regulation of organelle assembly#GO:1902115;regulation of microtubule cytoskeleton organization#GO:0070507;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;regulation of cellular component organization#GO:0051128;regulation of mitotic spindle organization#GO:0060236;regulation of cell cycle process#GO:0010564 microtubule organizing center#GO:0005815;cellular anatomical entity#GO:0110165;centriole#GO:0005814;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;ciliary transition zone#GO:0035869;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;ciliary basal body#GO:0036064;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;cell projection#GO:0042995;cilium#GO:0005929;spindle#GO:0005819 CIOIN|Ensembl=ENSCING00000013483.2|UniProtKB=F7BKI5 F7BKI5 PTHR11280:SF5 GLUCOSAMINE-6-PHOSPHATE ISOMERASE GLUCOSAMINE-6-PHOSPHATE ISOMERASE identical protein binding#GO:0042802;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;protein binding#GO:0005515;deaminase activity#GO:0019239;binding#GO:0005488;catalytic activity#GO:0003824 oxoacid metabolic process#GO:0043436;carbohydrate derivative metabolic process#GO:1901135;carbohydrate derivative catabolic process#GO:1901136;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;nitrogen compound metabolic process#GO:0006807;amino sugar catabolic process#GO:0046348;catabolic process#GO:0009056;amino sugar metabolic process#GO:0006040;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;amide metabolic process#GO:0043603;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 isomerase#PC00135;metabolite interconversion enzyme#PC00262 N-acetylglucosamine metabolism#P02756>Glucosamine-6-phosphate deaminase#P03041 CIOIN|Ensembl=ENSCING00000004171.3|UniProtKB=F7B629 F7B629 PTHR11785:SF512 AMINO ACID TRANSPORTER SOBREMESA, ISOFORM B L-amino acid transmembrane transporter activity#GO:0015179;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;amino acid transmembrane transporter activity#GO:0015171;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215;organic acid transmembrane transporter activity#GO:0005342 localization#GO:0051179;organic substance transport#GO:0071702;amino acid transmembrane transport#GO:0003333;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;amino acid transport#GO:0006865;organic anion transport#GO:0015711;organic acid transport#GO:0015849;transport#GO:0006810;nitrogen compound transport#GO:0071705;organic acid transmembrane transport#GO:1903825;carboxylic acid transport#GO:0046942;cellular process#GO:0009987;carboxylic acid transmembrane transport#GO:1905039 transporter#PC00227 CIOIN|Ensembl=ENSCING00000009636.3|UniProtKB=F6ZTZ7 F6ZTZ7 LOC100182530 PTHR11999:SF167 GROUP II PYRIDOXAL-5-PHOSPHATE DECARBOXYLASE AROMATIC-L-AMINO-ACID DECARBOXYLASE lyase activity#GO:0016829;carboxy-lyase activity#GO:0016831;carbon-carbon lyase activity#GO:0016830;catalytic activity#GO:0003824 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 decarboxylase#PC00089 Nicotine pharmacodynamics pathway#P06587>DDC#P06608;5-Hydroxytryptamine biosynthesis#P04371>Aromatic L-amino acid decarboxylase#P04400;Dopamine receptor mediated signaling pathway#P05912>DOPA decarb.#P05961;Adrenaline and noradrenaline biosynthesis#P00001>DOPA decarb.#P00066 CIOIN|Ensembl=ENSCING00000000419.3|UniProtKB=F7BL29 F7BL29 LOC100182102 PTHR45652:SF21 GLIAL FIBRILLARY ACIDIC PROTEIN ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 13-LIKE ISOFORM X1 structural molecule activity#GO:0005198;structural constituent of cytoskeleton#GO:0005200 cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;intermediate filament organization#GO:0045109;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cellular process#GO:0009987;intermediate filament cytoskeleton organization#GO:0045104;intermediate filament-based process#GO:0045103 supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intermediate filament#GO:0005882;intermediate filament cytoskeleton#GO:0045111;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;supramolecular fiber#GO:0099512;supramolecular polymer#GO:0099081;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 intermediate filament#PC00129 CIOIN|Ensembl=ENSCING00000015618.2|UniProtKB=F6ZK14 F6ZK14 LOC100181521 PTHR12326:SF12 PLECKSTRIN HOMOLOGY DOMAIN CONTAINING PROTEIN PLECKSTRIN HOMOLOGY AND RUN DOMAIN CONTAINING M1 CIOIN|Ensembl=ENSCING00000006835.3|UniProtKB=F7AZS2 F7AZS2 LOC100184214 PTHR12245:SF7 SPRY DOMAIN CONTAINING SOCS BOX PROTEIN F-BOX_SPRY DOMAIN-CONTAINING PROTEIN 1 cellular component biogenesis#GO:0044085;developmental process#GO:0032502;protein catabolic process#GO:0030163;organonitrogen compound catabolic process#GO:1901565;nervous system development#GO:0007399;modification-dependent macromolecule catabolic process#GO:0043632;system development#GO:0048731;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;cell junction assembly#GO:0034329;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular component assembly#GO:0022607;modification-dependent protein catabolic process#GO:0019941;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;cellular component organization#GO:0016043;cellular process#GO:0009987;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;synapse organization#GO:0050808;synapse assembly#GO:0007416;anatomical structure development#GO:0048856;cell junction organization#GO:0034330;multicellular organismal process#GO:0032501 SCF ubiquitin ligase complex#GO:0019005;synapse#GO:0045202;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;cullin-RING ubiquitin ligase complex#GO:0031461;catalytic complex#GO:1902494;transferase complex#GO:1990234;cell junction#GO:0030054;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000014867.2|UniProtKB=F7BFT5 F7BFT5 PTHR19300:SF38 BETA-1,4-GALACTOSYLTRANSFERASE BETA-1,4-GALACTOSYLTRANSFERASE UDP-galactosyltransferase activity#GO:0035250;galactosyltransferase activity#GO:0008378;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194;hexosyltransferase activity#GO:0016758 glycosylation#GO:0070085;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000003449.3|UniProtKB=F6WXY4 F6WXY4 PTHR24253:SF176 TRANSMEMBRANE PROTEASE SERINE CORIN, ISOFORM B serine protease#PC00203;protease#PC00190 CIOIN|Ensembl=ENSCING00000009152.3|UniProtKB=F7BB43 F7BB43 PTHR11412:SF136 MACROGLOBULIN / COMPLEMENT CD109 ANTIGEN protease inhibitor#PC00191 CIOIN|Ensembl=ENSCING00000001050.3|UniProtKB=F6UP59 F6UP59 LOC100180358 PTHR31040:SF1 NURIM NURIM CIOIN|Ensembl=ENSCING00000003502.3|UniProtKB=F7BHM4 F7BHM4 LOC100182742 PTHR47958:SF24 ATP-DEPENDENT RNA HELICASE DBP3 RNA HELICASE catalytic activity, acting on RNA#GO:0140098;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;helicase activity#GO:0004386;ATP-dependent activity#GO:0140657;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;catalytic activity, acting on a nucleic acid#GO:0140640;mRNA binding#GO:0003729 membrane-enclosed lumen#GO:0031974;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA helicase#PC00032 CIOIN|Ensembl=ENSCING00000001464.3|UniProtKB=F6UWK1 F6UWK1 PTHR12658:SF0 BETA-TUBULIN COFACTOR D TUBULIN-SPECIFIC CHAPERONE D nucleoside-triphosphatase regulator activity#GO:0060589;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;binding#GO:0005488;molecular function regulator activity#GO:0098772;protein binding#GO:0005515;enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;microtubule cytoskeleton organization#GO:0000226;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular component organization#GO:0016043;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;protein folding#GO:0006457;nitrogen compound metabolic process#GO:0006807;cytoskeleton organization#GO:0007010;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 chaperone#PC00072 CIOIN|Ensembl=ENSCING00000001319.3|UniProtKB=F6WVR4 F6WVR4 LOC100185669 PTHR14974:SF3 SIMILAR TO RIKEN CDNA 1700025G04 GENE SIMILAR TO RIKEN CDNA 1700025G04 GENE CIOIN|Ensembl=ENSCING00000007218.3|UniProtKB=Q4H342 Q4H342 Ci-NK4 PTHR24340:SF111 HOMEOBOX PROTEIN NKX HOMEOBOX DOMAIN-CONTAINING PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 CIOIN|Ensembl=ENSCING00000011361.2|UniProtKB=F6U922 F6U922 PTHR23280:SF25 4.1 G PROTEIN MOESIN_EZRIN_RADIXIN HOMOLOG 1 cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;actomyosin structure organization#GO:0031032;cellular component organization#GO:0016043;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165 CIOIN|Ensembl=ENSCING00000005904.3|UniProtKB=F6SH39 F6SH39 PTHR45636:SF49 PAIRED BOX PROTEIN PAX-6-RELATED-RELATED PAIRED BOX PROTEIN 3 HOMOLOG sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 homeodomain transcription factor#PC00119 CIOIN|Ensembl=ENSCING00000023308.1|UniProtKB=F6W833 F6W833 PTHR11119:SF3 XANTHINE-URACIL / VITAMIN C PERMEASE FAMILY MEMBER LD30822P transporter#PC00227 CIOIN|Ensembl=ENSCING00000020531.1|UniProtKB=H2XKM5 H2XKM5 LOC100181341 PTHR13946:SF16 DNA-DIRECTED RNA POLYMERASE I,II,III DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB11 catalytic activity, acting on RNA#GO:0140098;5'-3' RNA polymerase activity#GO:0034062;transferase activity#GO:0016740;DNA-directed 5'-3' RNA polymerase activity#GO:0003899;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;RNA polymerase activity#GO:0097747;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring phosphorus-containing groups#GO:0016772;RNA polymerase II activity#GO:0001055 cellular aromatic compound metabolic process#GO:0006725;DNA-templated transcription#GO:0006351;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;RNA biosynthetic process#GO:0032774;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;aromatic compound biosynthetic process#GO:0019438;transcription by RNA polymerase II#GO:0006366;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;RNA polymerase II, core complex#GO:0005665;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;DNA-directed RNA polymerase complex#GO:0000428;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695;RNA polymerase II, holoenzyme#GO:0016591;RNA polymerase complex#GO:0030880;protein-containing complex#GO:0032991;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 RNA metabolism protein#PC00031;DNA-directed RNA polymerase#PC00019 CIOIN|Ensembl=ENSCING00000003680.3|UniProtKB=F6XIP9 F6XIP9 LOC100181450 PTHR12399:SF0 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT 7 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT D nucleic acid binding#GO:0003676;translation regulator activity#GO:0045182;translation regulator activity, nucleic acid binding#GO:0090079;binding#GO:0005488;organic cyclic compound binding#GO:0097159;translation initiation factor activity#GO:0003743;translation factor activity, RNA binding#GO:0008135 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;translational initiation#GO:0006413;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;eukaryotic translation initiation factor 3 complex#GO:0005852;intracellular anatomical structure#GO:0005622 translation initiation factor#PC00224;translation factor#PC00223;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000016591.2|UniProtKB=F6UQX1 F6UQX1 PTHR23121:SF9 SODIUM-DEPENDENT GLUCOSE TRANSPORTER 1 SODIUM-DEPENDENT GLUCOSE TRANSPORTER 1 transmembrane transporter activity#GO:0022857;sugar transmembrane transporter activity#GO:0051119;transporter activity#GO:0005215;carbohydrate transmembrane transporter activity#GO:0015144 transporter#PC00227 CIOIN|Ensembl=ENSCING00000012548.2|UniProtKB=F7ATY3 F7ATY3 PTHR11380:SF5 TRANSCRIPTION INITIATION FACTOR TFIID/SUPT3-RELATED TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 13 cellular aromatic compound metabolic process#GO:0006725;DNA-templated transcription#GO:0006351;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;gene expression#GO:0010467;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;aromatic compound biosynthetic process#GO:0019438;transcription by RNA polymerase II#GO:0006366;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 RNA metabolism protein#PC00031;general transcription factor#PC00259 CIOIN|Ensembl=ENSCING00000024526.1|UniProtKB=H2Y1H5 H2Y1H5 PTHR48024:SF56 GEO13361P1-RELATED HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN A0 CIOIN|Ensembl=ENSCING00000024933.1|UniProtKB=H2XJG6 H2XJG6 PTHR10535:SF0 DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC1 DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC1 catalytic activity, acting on RNA#GO:0140098;5'-3' RNA polymerase activity#GO:0034062;transferase activity#GO:0016740;DNA-directed 5'-3' RNA polymerase activity#GO:0003899;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a nucleic acid#GO:0140640;RNA polymerase activity#GO:0097747;transferase activity, transferring phosphorus-containing groups#GO:0016772;RNA polymerase III activity#GO:0001056;RNA polymerase II activity#GO:0001055;RNA polymerase I activity#GO:0001054 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;DNA-templated transcription#GO:0006351;RNA metabolic process#GO:0016070;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;ncRNA metabolic process#GO:0034660;transcription by RNA polymerase I#GO:0006360;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;rRNA transcription#GO:0009303;nucleolar large rRNA transcription by RNA polymerase I#GO:0042790;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;transcription elongation by RNA polymerase I#GO:0006362;heterocycle metabolic process#GO:0046483;transcription by RNA polymerase III#GO:0006383;DNA-templated transcription elongation#GO:0006354;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;ncRNA transcription#GO:0098781;aromatic compound biosynthetic process#GO:0019438;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;RNA polymerase II, core complex#GO:0005665;organelle lumen#GO:0043233;nucleus#GO:0005634;DNA-directed RNA polymerase complex#GO:0000428;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nucleoplasm#GO:0005654;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;RNA polymerase II, holoenzyme#GO:0016591;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;RNA polymerase III complex#GO:0005666;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;RNA polymerase I complex#GO:0005736;nuclear protein-containing complex#GO:0140513 RNA metabolism protein#PC00031;DNA-directed RNA polymerase#PC00019 Transcription regulation by bZIP transcription factor#P00055>RNA Polymerase II#P01388;General transcription regulation#P00023>RNA Polymerase II#P00660 CIOIN|Ensembl=ENSCING00000019667.1|UniProtKB=H2XYD1 H2XYD1 PTHR46513:SF41 VITELLOGENIN RECEPTOR-LIKE PROTEIN-RELATED-RELATED LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN transmembrane signal receptor#PC00197 Wnt signaling pathway#P00057>LRP5/6#P01431 CIOIN|Ensembl=ENSCING00000001792.3|UniProtKB=F6X612 F6X612 PTHR20920:SF5 RPE-SPONDIN SMB DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000004141.3|UniProtKB=F6TV75 F6TV75 LOC100185252 PTHR45711:SF6 CHLORIDE CHANNEL PROTEIN CHLORIDE CHANNEL PROTEIN voltage-gated monoatomic ion channel activity#GO:0005244;inorganic molecular entity transmembrane transporter activity#GO:0015318;chloride channel activity#GO:0005254;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;voltage-gated channel activity#GO:0022832;gated channel activity#GO:0022836;chloride transmembrane transporter activity#GO:0015108;monoatomic anion transmembrane transporter activity#GO:0008509;inorganic anion transmembrane transporter activity#GO:0015103;transporter activity#GO:0005215;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 CIOIN|Ensembl=ENSCING00000006610.3|UniProtKB=F6QQ08 F6QQ08 LOC100180799 PTHR23415:SF4 CYCLIN-DEPENDENT KINASES REGULATORY SUBUNIT/60S RIBOSOME SUBUNIT BIOGENESIS PROTEIN NIP7 60S RIBOSOME SUBUNIT BIOGENESIS PROTEIN NIP7 HOMOLOG cellular component organization or biogenesis#GO:0071840;cellular component biogenesis#GO:0044085;ribosome biogenesis#GO:0042254;cellular process#GO:0009987;ribosomal large subunit biogenesis#GO:0042273;ribonucleoprotein complex biogenesis#GO:0022613 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;preribosome, large subunit precursor#GO:0030687;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;nuclear lumen#GO:0031981 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000006225.3|UniProtKB=F6YBW0 F6YBW0 PTHR24078:SF553 DNAJ HOMOLOG SUBFAMILY C MEMBER DNAJ HOMOLOG SUBFAMILY B MEMBER 5 protein binding#GO:0005515;protein-folding chaperone binding#GO:0051087;unfolded protein binding#GO:0051082;binding#GO:0005488 macromolecule biosynthetic process#GO:0009059;chaperone-mediated protein folding#GO:0061077;chaperone cofactor-dependent protein refolding#GO:0051085;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein folding#GO:0006457;'de novo' protein folding#GO:0006458;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 chaperone#PC00072 CIOIN|Ensembl=ENSCING00000003018.3|UniProtKB=F6QB79 F6QB79 LOC100176987 PTHR11814:SF257 SULFATE TRANSPORTER ANION TRANSPORTER SULP-7D inorganic molecular entity transmembrane transporter activity#GO:0015318;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;organic acid transmembrane transporter activity#GO:0005342;chloride transmembrane transporter activity#GO:0015108;monoatomic anion transmembrane transporter activity#GO:0008509;organic anion transmembrane transporter activity#GO:0008514;inorganic anion transmembrane transporter activity#GO:0015103;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 transporter#PC00227 CIOIN|Ensembl=ENSCING00000023792.1|UniProtKB=H2XRD8 H2XRD8 PTHR12486:SF5 APRATAXIN-RELATED ADENOSINE 5'-MONOPHOSPHORAMIDASE HINT3 damaged DNA-binding protein#PC00086;DNA metabolism protein#PC00009 CIOIN|Ensembl=ENSCING00000017912.1|UniProtKB=H2XY39 H2XY39 LOC100179843 PTHR12532:SF0 TRANSLATIONAL ACTIVATOR OF CYTOCHROME C OXIDASE 1 TRANSLATIONAL ACTIVATOR OF CYTOCHROME C OXIDASE 1 CIOIN|Ensembl=ENSCING00000001641.3|UniProtKB=F6YIX5 F6YIX5 PTHR23151:SF90 DIHYDROLIPOAMIDE ACETYL/SUCCINYL-TRANSFERASE-RELATED DIHYDROLIPOYLLYSINE-RESIDUE ACETYLTRANSFERASE COMPONENT OF PYRUVATE DEHYDROGENASE COMPLEX, MITOCHONDRIAL-RELATED transferase#PC00220;acetyltransferase#PC00038;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000021779.1|UniProtKB=F6ZU45 F6ZU45 PTHR13379:SF0 UNCHARACTERIZED DUF1308 UPF0415 PROTEIN C7ORF25 CIOIN|Ensembl=ENSCING00000000618.3|UniProtKB=F6RRK4 F6RRK4 LOC100177240 PTHR45640:SF26 HEAT SHOCK PROTEIN HSP-12.2-RELATED RE23625P chaperone#PC00072 VEGF signaling pathway#P00056>HSP27#P01412;Angiogenesis#P00005>HSP27#P00231 CIOIN|Ensembl=ENSCING00000004394.3|UniProtKB=F7AUH4 F7AUH4 LOC100187432 PTHR11661:SF1 60S RIBOSOMAL PROTEIN L12 LARGE RIBOSOMAL SUBUNIT PROTEIN UL11M structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;structural molecule activity#GO:0005198;rRNA binding#GO:0019843;binding#GO:0005488;organic cyclic compound binding#GO:0097159 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;large ribosomal subunit#GO:0015934;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000004355.3|UniProtKB=F6S6B2 F6S6B2 PTHR10336:SF159 PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C FAMILY PROTEIN 1-PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE PHOSPHODIESTERASE GAMMA hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;phospholipase C activity#GO:0004629;phosphoric diester hydrolase activity#GO:0008081;phospholipase activity#GO:0004620;phosphoric ester hydrolase activity#GO:0042578 lipid metabolic process#GO:0006629;negative regulation of biological process#GO:0048519;signal transduction#GO:0007165;regulation of sequestering of calcium ion#GO:0051282;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;regulation of localization#GO:0032879;inorganic ion transmembrane transport#GO:0098660;phospholipid metabolic process#GO:0006644;phosphorus metabolic process#GO:0006793;calcium ion transport#GO:0006816;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;glycerolipid metabolic process#GO:0046486;establishment of localization#GO:0051234;monoatomic cation transport#GO:0006812;intracellular signal transduction#GO:0035556;negative regulation of cellular process#GO:0048523;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;calcium ion transmembrane transport#GO:0070588;cellular metabolic process#GO:0044237;release of sequestered calcium ion into cytosol#GO:0051209;cell communication#GO:0007154;glycerophospholipid metabolic process#GO:0006650;phosphatidylinositol metabolic process#GO:0046488;cellular process#GO:0009987;primary metabolic process#GO:0044238;localization#GO:0051179;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;monoatomic ion transmembrane transport#GO:0034220;calcium ion transmembrane import into cytosol#GO:0097553;biological regulation#GO:0065007;organophosphate metabolic process#GO:0019637;monoatomic ion transport#GO:0006811;cellular lipid metabolic process#GO:0044255;negative regulation of sequestering of calcium ion#GO:0051283;monoatomic cation transmembrane transport#GO:0098655 cell leading edge#GO:0031252;ruffle membrane#GO:0032587;ruffle#GO:0001726;leading edge membrane#GO:0031256;plasma membrane region#GO:0098590;cell projection membrane#GO:0031253;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;plasma membrane#GO:0005886 phospholipase#PC00186 VEGF signaling pathway#P00056>PLC-gamma#P01414;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PLCbetagamma#P00874;FGF signaling pathway#P00021>PLCgamma#P00638;Axon guidance mediated by netrin#P00009>Phospholipase C#P00362;Thyrotropin-releasing hormone receptor signaling pathway#P04394>PLC#P04581;Angiogenesis#P00005>PLC-gamma#P00256;EGF receptor signaling pathway#P00018>PLCgamma#P00556;PDGF signaling pathway#P00047>PLCgamma#P01171;Oxytocin receptor mediated signaling pathway#P04391>PLC beta#P04530;5HT2 type receptor mediated signaling pathway#P04374>PLC#P04412;Histamine H1 receptor mediated signaling pathway#P04385>PLC#P04484 CIOIN|Ensembl=ENSCING00000012290.2|UniProtKB=F7BEL6 F7BEL6 LOC104265691 PTHR23241:SF102 LATE EMBRYOGENESIS ABUNDANT PLANTS LEA-RELATED LD23009P CIOIN|Ensembl=ENSCING00000010075.3|UniProtKB=F6QCI8 F6QCI8 PTHR24114:SF50 LEUCINE RICH REPEAT FAMILY PROTEIN RNI-LIKE PROTEIN CIOIN|Ensembl=ENSCING00000008018.3|UniProtKB=F6SSN4 F6SSN4 LOC100180518 PTHR12921:SF0 UBIQUITIN-FOLD MODIFIER-CONJUGATING ENZYME 1 UBIQUITIN-FOLD MODIFIER-CONJUGATING ENZYME 1 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;post-translational protein modification#GO:0043687;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000020729.1|UniProtKB=H2XM04 H2XM04 LOC100179601 PTHR33887:SF5 PB1 DOMAIN-CONTAINING PROTEIN PB1 DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000003291.3|UniProtKB=F6W248 F6W248 LOC100181765 PTHR15350:SF2 COP9 SIGNALOSOME COMPLEX SUBUNIT 7/DENDRITIC CELL PROTEIN GA17 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT M macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cytoplasmic translation#GO:0002181;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cytoplasmic translational initiation#GO:0002183;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;translation#GO:0006412;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;translational initiation#GO:0006413;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;eukaryotic translation initiation factor 3 complex#GO:0005852;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000012713.2|UniProtKB=F6TEM5 F6TEM5 PTHR46179:SF25 ZINC FINGER PROTEIN METAL RESPONSE ELEMENT-BINDING TRANSCRIPTION FACTOR-1, ISOFORM C regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 CIOIN|Ensembl=ENSCING00000014756.2|UniProtKB=F6W8U8 F6W8U8 LOC100183635 PTHR11955:SF89 FATTY ACID BINDING PROTEIN FATTY ACID-BINDING PROTEIN, INTESTINAL fatty acid binding#GO:0005504;small molecule binding#GO:0036094;binding#GO:0005488;carboxylic acid binding#GO:0031406;lipid binding#GO:0008289;ion binding#GO:0043167;organic acid binding#GO:0043177;anion binding#GO:0043168 localization#GO:0051179;monocarboxylic acid transport#GO:0015718;organic substance transport#GO:0071702;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;organic anion transport#GO:0015711;fatty acid transport#GO:0015908;organic acid transport#GO:0015849;transport#GO:0006810;carboxylic acid transport#GO:0046942;lipid localization#GO:0010876;lipid transport#GO:0006869 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transfer/carrier protein#PC00219 CIOIN|Ensembl=ENSCING00000025074.1|UniProtKB=H2XL49 H2XL49 PTHR19134:SF562 RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE PROTEIN-TYROSINE-PHOSPHATASE hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;protein tyrosine phosphatase activity#GO:0004725;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 protein phosphatase#PC00195;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000002391.3|UniProtKB=F6QZY3 F6QZY3 PTHR23427:SF1 SURFEIT LOCUS PROTEIN SURFEIT LOCUS PROTEIN 4 endomembrane system organization#GO:0010256;cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;cellular process#GO:0009987;Golgi organization#GO:0007030;organelle organization#GO:0006996 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chaperone#PC00072 CIOIN|Ensembl=ENSCING00000003279.3|UniProtKB=F6WN12 F6WN12 PTHR11785:SF512 AMINO ACID TRANSPORTER SOBREMESA, ISOFORM B L-amino acid transmembrane transporter activity#GO:0015179;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;amino acid transmembrane transporter activity#GO:0015171;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215;organic acid transmembrane transporter activity#GO:0005342 localization#GO:0051179;organic substance transport#GO:0071702;amino acid transmembrane transport#GO:0003333;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;amino acid transport#GO:0006865;organic anion transport#GO:0015711;organic acid transport#GO:0015849;transport#GO:0006810;nitrogen compound transport#GO:0071705;organic acid transmembrane transport#GO:1903825;carboxylic acid transport#GO:0046942;cellular process#GO:0009987;carboxylic acid transmembrane transport#GO:1905039 transporter#PC00227 CIOIN|Ensembl=ENSCING00000008875.3|UniProtKB=F6QY06 F6QY06 PTHR45828:SF33 CYTOCHROME B561/FERRIC REDUCTASE TRANSMEMBRANE DOMON DOMAIN-CONTAINING PROTEIN cellular anatomical entity#GO:0110165;membrane#GO:0016020 reductase#PC00198;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000018966.1|UniProtKB=H2Y001 H2Y001 PTHR18853:SF10 FORKHEAD-ASSOCIATED DOMAIN-CONTAINING PROTEIN 1-RELATED FHA DOMAIN-CONTAINING PROTEIN helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 CIOIN|Ensembl=ENSCING00000011365.2|UniProtKB=F6U8Q2 F6U8Q2 PTHR13935:SF153 ACHAETE-SCUTE TRANSCRIPTION FACTOR-RELATED ACHAETE-SCUTE FAMILY BHLH TRANSCRIPTION FACTOR 1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of nitrogen compound metabolic process#GO:0051173;neurogenesis#GO:0022008;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nitrogen compound metabolic process#GO:0051171;animal organ development#GO:0048513;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;regulation of cell differentiation#GO:0045595;regulation of multicellular organismal development#GO:2000026;nervous system development#GO:0007399;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;neuron differentiation#GO:0030182;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;cellular developmental process#GO:0048869;regulation of multicellular organismal process#GO:0051239;regulation of cell development#GO:0060284;regulation of DNA-templated transcription#GO:0006355;multicellular organism development#GO:0007275;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of neurogenesis#GO:0050767;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;positive regulation of RNA metabolic process#GO:0051254;generation of neurons#GO:0048699;sensory organ development#GO:0007423;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;basic helix-loop-helix transcription factor#PC00055 CIOIN|Ensembl=ENSCING00000011484.2|UniProtKB=F6XHE4 F6XHE4 PTHR12305:SF60 PHOSPHATASE WITH HOMOLOGY TO TENSIN PHOSPHATIDYLINOSITOL 3,4,5-TRISPHOSPHATE 3-PHOSPHATASE TPTE2-RELATED hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 cellular metabolic process#GO:0044237;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;metabolic process#GO:0008152;phosphate-containing compound metabolic process#GO:0006796;dephosphorylation#GO:0016311 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 protein phosphatase#PC00195;protein modifying enzyme#PC00260 Hypoxia response via HIF activation#P00030>PTEN#P00824;p53 pathway#P00059>PTEN#G01579;p53 pathway feedback loops 2#P04398>PTEN#P04658;p53 pathway feedback loops 2#P04398>PTEN#G04714;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>PTEN#P00905;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>PTEN#G04675;p53 pathway#P00059>PTEN#P01480 CIOIN|Ensembl=ENSCING00000001627.3|UniProtKB=F7B8H6 F7B8H6 LOC100187498 PTHR45655:SF10 GUANYLATE CYCLASE SOLUBLE SUBUNIT BETA-2 SOLUBLE GUANYLATE CYCLASE 88E lyase activity#GO:0016829;cyclase activity#GO:0009975;phosphorus-oxygen lyase activity#GO:0016849;catalytic activity#GO:0003824 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;response to abiotic stimulus#GO:0009628;intracellular signaling cassette#GO:0141124;cGMP-mediated signaling#GO:0019934;cellular process#GO:0009987;signaling#GO:0023052;response to oxygen levels#GO:0070482;cyclic-nucleotide-mediated signaling#GO:0019935 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622 guanylate cyclase#PC00114 CIOIN|Ensembl=ENSCING00000006925.3|UniProtKB=F6WAE5 F6WAE5 LOC100182651 PTHR23041:SF78 RING FINGER DOMAIN-CONTAINING E3 UBIQUITIN-PROTEIN LIGASE RNF4 CIOIN|Ensembl=ENSCING00000021827.1|UniProtKB=H2XRW6 H2XRW6 PTHR24418:SF460 TYROSINE-PROTEIN KINASE PROTEIN KINASE DOMAIN-CONTAINING PROTEIN protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;non-membrane spanning protein tyrosine kinase activity#GO:0004715;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 non-receptor tyrosine protein kinase#PC00168 CIOIN|Ensembl=ENSCING00000010856.3|UniProtKB=F6ZSR8 F6ZSR8 PTHR24056:SF508 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE 10 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;nitrogen compound metabolic process#GO:0006807;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;regulation of mitotic cell cycle#GO:0007346;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 CIOIN|Ensembl=ENSCING00000020755.1|UniProtKB=H2XJN8 H2XJN8 LOC100183218 PTHR10772:SF0 10 KDA HEAT SHOCK PROTEIN 10 KDA HEAT SHOCK PROTEIN, MITOCHONDRIAL cation binding#GO:0043169;unfolded protein binding#GO:0051082;small molecule binding#GO:0036094;binding#GO:0005488;metal ion binding#GO:0046872;protein binding#GO:0005515;protein-folding chaperone binding#GO:0051087;ion binding#GO:0043167 macromolecule biosynthetic process#GO:0009059;chaperone cofactor-dependent protein refolding#GO:0051085;chaperone-mediated protein folding#GO:0061077;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein folding#GO:0006457;nitrogen compound metabolic process#GO:0006807;'de novo' protein folding#GO:0006458;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chaperonin#PC00073 CIOIN|Ensembl=ENSCING00000011479.2|UniProtKB=F6XIB4 F6XIB4 PTHR24243:SF234 G-PROTEIN COUPLED RECEPTOR GROWTH HORMONE SECRETAGOGUE RECEPTOR TYPE 1-LIKE signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 CIOIN|Ensembl=ENSCING00000003493.3|UniProtKB=F6TLX0 F6TLX0 PTHR24416:SF600 TYROSINE-PROTEIN KINASE RECEPTOR PDGF- AND VEGF-RECEPTOR RELATED, ISOFORM J signaling receptor activity#GO:0038023;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;molecular transducer activity#GO:0060089;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672;transmembrane signaling receptor activity#GO:0004888 signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;positive regulation of cellular metabolic process#GO:0031325;developmental process#GO:0032502;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;regulation of molecular function#GO:0065009;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;positive regulation of phosphorylation#GO:0042327;cellular response to stimulus#GO:0051716;positive regulation of catalytic activity#GO:0043085;multicellular organism development#GO:0007275;positive regulation of phosphorus metabolic process#GO:0010562;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphate metabolic process#GO:0045937;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;multicellular organismal process#GO:0032501;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 receptor complex#GO:0043235;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 CIOIN|Ensembl=ENSCING00000000540.3|UniProtKB=F6Q8D1 F6Q8D1 PTHR43881:SF1 GAMMA-GLUTAMYLTRANSPEPTIDASE (AFU_ORTHOLOGUE AFUA_4G13580) GAMMA-GLUTAMYLTRANSPEPTIDASE (AFU_ORTHOLOGUE AFUA_4G13580) protease#PC00190 CIOIN|Ensembl=ENSCING00000003708.3|UniProtKB=F6WUM1 F6WUM1 PTHR16023:SF0 TAX1 BINDING PROTEIN-RELATED PROTEIN VAC14 HOMOLOG lipid metabolic process#GO:0006629;phospholipid biosynthetic process#GO:0008654;organophosphate biosynthetic process#GO:0090407;phosphatidylinositol biosynthetic process#GO:0006661;glycerolipid biosynthetic process#GO:0045017;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;phosphatidylinositol metabolic process#GO:0046488;glycerophospholipid metabolic process#GO:0006650;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;glycerophospholipid biosynthetic process#GO:0046474;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;phosphatidylinositol 3-kinase complex#GO:0005942;catalytic complex#GO:1902494;transferase complex#GO:1990234;vacuolar membrane#GO:0005774;vacuole#GO:0005773;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endosome membrane#GO:0010008;phosphatidylinositol 3-kinase complex, class III#GO:0035032;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695;extrinsic component of membrane#GO:0019898;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle membrane#GO:0030659 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000008373.3|UniProtKB=F6YEG0 F6YEG0 PTHR11804:SF84 PROTEASE M3 THIMET OLIGOPEPTIDASE-RELATED SACCHAROLYSIN hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;peptide metabolic process#GO:0006518;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000023156.1|UniProtKB=H2XY27 H2XY27 PTHR43591:SF24 METHYLTRANSFERASE 2-METHOXY-6-POLYPRENYL-1,4-BENZOQUINOL METHYLASE, MITOCHONDRIAL methyltransferase activity#GO:0008168;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824 methyltransferase#PC00155;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000001273.3|UniProtKB=F6ZW63 F6ZW63 hox1 PTHR45946:SF4 HOMEOBOX PROTEIN ROUGH-RELATED HOMEOBOX PROTEIN ROUGH-RELATED sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 CIOIN|Ensembl=ENSCING00000007435.3|UniProtKB=F7APA8 F7APA8 PTHR11062:SF73 EXOSTOSIN HEPARAN SULFATE GLYCOSYLTRANSFERASE -RELATED EXOSTOSIN-LIKE 3 glycosyltransferase#PC00111 CIOIN|Ensembl=ENSCING00000004545.3|UniProtKB=F6ZQR9 F6ZQR9 LOC100181211 PTHR24388:SF79 ZINC FINGER PROTEIN C2H2-TYPE DOMAIN-CONTAINING PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 CIOIN|Ensembl=ENSCING00000001171.3|UniProtKB=F6WB20 F6WB20 LOC100185899 PTHR24322:SF746 PKSB SHORT CHAIN DEHYDROGENASE_REDUCTASE FAMILY 16C MEMBER 5 oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;lipid droplet#GO:0005811;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 dehydrogenase#PC00092;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000005746.3|UniProtKB=F6PZM1 F6PZM1 LOC100179838 PTHR11910:SF1 ATP SYNTHASE DELTA CHAIN ATP SYNTHASE SUBUNIT O, MITOCHONDRIAL monoatomic cation channel activity#GO:0005261;ligase activity#GO:0016874;inorganic molecular entity transmembrane transporter activity#GO:0015318;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;catalytic activity#GO:0003824;proton transmembrane transporter activity#GO:0015078;proton channel activity#GO:0015252;proton-transporting ATP synthase activity, rotational mechanism#GO:0046933;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;inorganic cation transmembrane transporter activity#GO:0022890;channel activity#GO:0015267;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 cellular aromatic compound metabolic process#GO:0006725;ribonucleoside triphosphate metabolic process#GO:0009199;nucleoside triphosphate metabolic process#GO:0009141;carbohydrate derivative metabolic process#GO:1901135;ATP biosynthetic process#GO:0006754;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;energy derivation by oxidation of organic compounds#GO:0015980;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ATP metabolic process#GO:0046034;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;purine nucleoside triphosphate biosynthetic process#GO:0009145;aerobic respiration#GO:0009060;cellular respiration#GO:0045333;heterocycle metabolic process#GO:0046483;purine ribonucleoside triphosphate metabolic process#GO:0009205;generation of precursor metabolites and energy#GO:0006091;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;ribonucleoside triphosphate biosynthetic process#GO:0009201;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;proton motive force-driven ATP synthesis#GO:0015986;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;oxidative phosphorylation#GO:0006119;aromatic compound biosynthetic process#GO:0019438;nucleoside triphosphate biosynthetic process#GO:0009142;organophosphate metabolic process#GO:0019637;purine nucleoside triphosphate metabolic process#GO:0009144;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;proton-transporting two-sector ATPase complex, proton-transporting domain#GO:0033177;ATPase complex#GO:1904949;organelle inner membrane#GO:0019866;mitochondrial proton-transporting ATP synthase complex#GO:0005753;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;proton-transporting two-sector ATPase complex#GO:0016469;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)#GO:0000276;mitochondrial envelope#GO:0005740;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227;proton-transporting ATP synthase complex, coupling factor F(o)#GO:0045263;proton-transporting ATP synthase complex#GO:0045259;mitochondrial protein-containing complex#GO:0098798 ATP synthase#PC00002;primary active transporter#PC00068;transporter#PC00227 CIOIN|Ensembl=ENSCING00000008762.3|UniProtKB=F6T065 F6T065 PTHR12515:SF5 STERILE ALPHA MOTIF DOMAIN CONTAINING PROTEIN 4-RELATED PROTEIN SMAUG RNA binding#GO:0003723;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 negative regulation of gene expression#GO:0010629;regulation of catabolic process#GO:0009894;heterocycle catabolic process#GO:0046700;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;nucleobase-containing compound metabolic process#GO:0006139;RNA destabilization#GO:0050779;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;regulation of RNA stability#GO:0043487;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;nuclear-transcribed mRNA poly(A) tail shortening#GO:0000289;positive regulation of mRNA catabolic process#GO:0061014;regulation of cellular process#GO:0050794;post-transcriptional regulation of gene expression#GO:0010608;positive regulation of catabolic process#GO:0009896;mRNA destabilization#GO:0061157;nucleobase-containing compound catabolic process#GO:0034655;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;regulation of mRNA stability#GO:0043488;RNA metabolic process#GO:0016070;positive regulation of cellular catabolic process#GO:0031331;cellular nitrogen compound catabolic process#GO:0044270;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;mRNA catabolic process#GO:0006402;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;regulation of gene expression#GO:0010468;organic substance catabolic process#GO:1901575;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;positive regulation of mRNA metabolic process#GO:1903313;heterocycle metabolic process#GO:0046483;negative regulation of biosynthetic process#GO:0009890;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;positive regulation of RNA metabolic process#GO:0051254 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;P-body#GO:0000932;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic ribonucleoprotein granule#GO:0036464 CIOIN|Ensembl=ENSCING00000012641.2|UniProtKB=F6WS50 F6WS50 PTHR11702:SF43 DEVELOPMENTALLY REGULATED GTP-BINDING PROTEIN-RELATED GTP-BINDING PROTEIN 10 GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;ion binding#GO:0043167;anion binding#GO:0043168 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000003756.3|UniProtKB=F6U6F4 F6U6F4 PTHR23510:SF16 INNER MEMBRANE TRANSPORT PROTEIN YAJR MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000001009.2|UniProtKB=F6Y110 F6Y110 PTHR31873:SF6 L-ASPARTATE DEHYDROGENASE-RELATED ASPARTATE DEHYDROGENASE DOMAIN-CONTAINING PROTEIN dehydrogenase#PC00092;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000006480.3|UniProtKB=F6PV45 F6PV45 LOC100176531 PTHR11468:SF13 GLYCOGEN PHOSPHORYLASE GLYCOGEN PHOSPHORYLASE transferase activity#GO:0016740;small molecule binding#GO:0036094;glycosyltransferase activity#GO:0016757;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;anion binding#GO:0043168;hexosyltransferase activity#GO:0016758 glucan metabolic process#GO:0044042;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;glycogen metabolic process#GO:0005977;generation of precursor metabolites and energy#GO:0006091;cellular metabolic process#GO:0044237;cellular process#GO:0009987;energy derivation by oxidation of organic compounds#GO:0015980;primary metabolic process#GO:0044238;polysaccharide metabolic process#GO:0005976;carbohydrate catabolic process#GO:0016052;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;energy reserve metabolic process#GO:0006112;carbohydrate metabolic process#GO:0005975;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111 CIOIN|Ensembl=ENSCING00000000931.3|UniProtKB=F6TDD6 F6TDD6 LOC100184133 PTHR15239:SF6 NUCLEAR EXPORT MEDIATOR FACTOR NEMF RIBOSOME QUALITY CONTROL COMPLEX SUBUNIT NEMF tRNA binding#GO:0000049;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159;ribosome binding#GO:0043022;ribonucleoprotein complex binding#GO:0043021;protein-containing complex binding#GO:0044877 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular component organization#GO:0016043;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;organelle disassembly#GO:1903008;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;cellular component organization or biogenesis#GO:0071840;peptide biosynthetic process#GO:0043043;cellular component disassembly#GO:0022411;organelle organization#GO:0006996;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;translational elongation#GO:0006414;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 protein-containing complex#GO:0032991 CIOIN|Ensembl=ENSCING00000005740.3|UniProtKB=F6PZN0 F6PZN0 PTHR10030:SF37 ALPHA-L-FUCOSIDASE ALPHA-L-FUCOSIDASE-RELATED hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 monosaccharide metabolic process#GO:0005996;carbohydrate derivative metabolic process#GO:1901135;glycosyl compound catabolic process#GO:1901658;carbohydrate derivative catabolic process#GO:1901136;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;hexose metabolic process#GO:0019318;glycosyl compound metabolic process#GO:1901657;carbohydrate metabolic process#GO:0005975;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;lysosome#GO:0005764;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;lytic vacuole#GO:0000323;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosidase#PC00110;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000001532.3|UniProtKB=F6Z3I6 F6Z3I6 PTHR48020:SF12 PROTON MYO-INOSITOL COTRANSPORTER PROTON MYO-INOSITOL COTRANSPORTER transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 localization#GO:0051179;establishment of localization#GO:0051234;cellular process#GO:0009987;transmembrane transport#GO:0055085;transport#GO:0006810 cellular anatomical entity#GO:0110165;membrane#GO:0016020 transporter#PC00227 CIOIN|Ensembl=ENSCING00000009349.3|UniProtKB=F6Z3N0 F6Z3N0 PTHR11829:SF402 FORKHEAD BOX PROTEIN FORK HEAD DOMAIN-CONTAINING PROTEIN FD3-RELATED sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;anatomical structure morphogenesis#GO:0009653;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 CIOIN|Ensembl=ENSCING00000013360.2|UniProtKB=F6YWN2 F6YWN2 LOC100176555 PTHR12485:SF1 NADH-UBIQUINONE OXIDOREDUCTASE SUBUNIT B NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 7 mitochondrial ATP synthesis coupled electron transport#GO:0042775;aerobic respiration#GO:0009060;cellular respiration#GO:0045333;mitochondrial electron transport, NADH to ubiquinone#GO:0006120;respiratory electron transport chain#GO:0022904;aerobic electron transport chain#GO:0019646;oxidative phosphorylation#GO:0006119;generation of precursor metabolites and energy#GO:0006091;electron transport chain#GO:0022900;ATP synthesis coupled electron transport#GO:0042773;cellular metabolic process#GO:0044237;cellular process#GO:0009987;energy derivation by oxidation of organic compounds#GO:0015980;metabolic process#GO:0008152 envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;respiratory chain complex#GO:0098803;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transporter complex#GO:1990351;oxidoreductase complex#GO:1990204;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;respirasome#GO:0070469;mitochondrial respiratory chain complex I#GO:0005747;protein-containing complex#GO:0032991;mitochondrial envelope#GO:0005740;mitochondrial respirasome#GO:0005746;transmembrane transporter complex#GO:1902495;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227;respiratory chain complex I#GO:0045271;NADH dehydrogenase complex#GO:0030964;mitochondrial protein-containing complex#GO:0098798 oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000022323.1|UniProtKB=H2XN77 H2XN77 PTHR43086:SF2 VERY-LONG-CHAIN 3-OXOOACYL-COA REDUCTASE HYDROXYSTEROID DEHYDROGENASE-LIKE PROTEIN 1 organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;monocarboxylic acid biosynthetic process#GO:0072330;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;fatty acid metabolic process#GO:0006631;small molecule biosynthetic process#GO:0044283;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;fatty acid biosynthetic process#GO:0006633 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 reductase#PC00198;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000007490.3|UniProtKB=F6XWE7 F6XWE7 PTHR24345:SF0 SERINE/THREONINE-PROTEIN KINASE PLK CELL CYCLE SERINE_THREONINE-PROTEIN KINASE CDC5_MSD2 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000009289.3|UniProtKB=F7B9X1 F7B9X1 LOC100177165 PTHR43975:SF2 ZGC:101858 EG:BACR7A4.14 PROTEIN-RELATED CIOIN|Ensembl=ENSCING00000001830.3|UniProtKB=F6WIH5 F6WIH5 PTHR21348:SF2 FAMILY NOT NAMED SULFIREDOXIN-1 CIOIN|Ensembl=ENSCING00000000318.3|UniProtKB=F6ZFU8 F6ZFU8 LOC100180533 PTHR15925:SF2 MITOCHONDRIAL RIBOSOMAL PROTEIN S23 SMALL RIBOSOMAL SUBUNIT PROTEIN MS23 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000011388.2|UniProtKB=F6TJB5 F6TJB5 PTHR12849:SF0 RNA LARIAT DEBRANCHING ENZYME LARIAT DEBRANCHING ENZYME catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a nucleic acid#GO:0140640;endonuclease activity#GO:0004519;RNA nuclease activity#GO:0004540;RNA endonuclease activity#GO:0004521 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 endoribonuclease#PC00094;RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000007850.3|UniProtKB=F6W680 F6W680 PTHR11339:SF414 EXTRACELLULAR MATRIX GLYCOPROTEIN RELATED VON WILLEBRAND FACTOR-LIKE extracellular matrix protein#PC00102 CIOIN|Ensembl=ENSCING00000003221.3|UniProtKB=F6ZP71 F6ZP71 PTHR24089:SF57 SOLUTE CARRIER FAMILY 25 FI05451P carbohydrate derivative transmembrane transporter activity#GO:1901505;purine nucleotide transmembrane transporter activity#GO:0015216;nucleobase-containing compound transmembrane transporter activity#GO:0015932;transmembrane transporter activity#GO:0022857;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215 localization#GO:0051179;organic substance transport#GO:0071702;organophosphate ester transport#GO:0015748;establishment of localization#GO:0051234;organic anion transport#GO:0015711;nucleobase-containing compound transport#GO:0015931;transport#GO:0006810;nitrogen compound transport#GO:0071705;carbohydrate derivative transport#GO:1901264 mitochondrial carrier protein#PC00158;secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000025062.1|UniProtKB=H2Y0S6 H2Y0S6 PTHR15137:SF9 TRANSCRIPTION INITIATION FACTOR TFIID TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 2 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;chromatin binding#GO:0003682;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;protein-containing complex binding#GO:0044877 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;DNA-templated transcription#GO:0006351;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;transcription initiation at RNA polymerase II promoter#GO:0006367;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;DNA-templated transcription initiation#GO:0006352;aromatic compound biosynthetic process#GO:0019438;transcription by RNA polymerase II#GO:0006366;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;DNA-directed RNA polymerase complex#GO:0000428;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nucleoplasm#GO:0005654;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;transcription factor TFIID complex#GO:0005669;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622;RNA polymerase II, holoenzyme#GO:0016591;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;transcription regulator complex#GO:0005667;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 general transcription factor#PC00259 General transcription regulation#P00023>TBP-associated factors#P00658;Transcription regulation by bZIP transcription factor#P00055>TBP-associated factors#P01385 CIOIN|Ensembl=ENSCING00000003485.2|UniProtKB=F6UA25 F6UA25 LOC100178356 PTHR35332:SF2 REGULATION OF ENOLASE PROTEIN 1 REGULATION OF ENOLASE PROTEIN 1 CIOIN|Ensembl=ENSCING00000008651.3|UniProtKB=F6ZYE8 F6ZYE8 LOC100182716 PTHR11081:SF70 FLAP ENDONUCLEASE FAMILY MEMBER FLAP ENDONUCLEASE GEN HOMOLOG 1 DNA endonuclease activity#GO:0004520;hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;catalytic activity#GO:0003824;endonuclease activity#GO:0004519;hydrolase activity#GO:0016787;catalytic activity, acting on a nucleic acid#GO:0140640;DNA nuclease activity#GO:0004536;catalytic activity, acting on DNA#GO:0140097 DNA metabolism protein#PC00009;exodeoxyribonuclease#PC00098 CIOIN|Ensembl=ENSCING00000014045.2|UniProtKB=F6THS9 F6THS9 PTHR11474:SF126 TYROSINASE FAMILY MEMBER TYROSINASE-LIKE PROTEIN TYR-1-RELATED oxygenase#PC00177;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000000188.3|UniProtKB=F6WFK7 F6WFK7 LOC100187122 PTHR43625:SF4 AFLATOXIN B1 ALDEHYDE REDUCTASE ALDO-KETO REDUCTASE FAMILY 7 LIKE (GENE_PSEUDOGENE) oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 reductase#PC00198;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000009641.3|UniProtKB=F6ZTX2 F6ZTX2 PTHR43447:SF49 ALPHA-AMYLASE ALPHA-AMYLASE amylase#PC00048;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000020036.1|UniProtKB=H2Y0K6 H2Y0K6 PTHR10877:SF194 POLYCYSTIN FAMILY MEMBER LOCATION OF VULVA DEFECTIVE 1 calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;metal ion transmembrane transporter activity#GO:0046873;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267;monoatomic ion channel activity#GO:0005216 detection of stimulus#GO:0051606;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;detection of mechanical stimulus#GO:0050982;response to mechanical stimulus#GO:0009612;response to abiotic stimulus#GO:0009628 cellular anatomical entity#GO:0110165;membrane#GO:0016020 ion channel#PC00133;transporter#PC00227 CIOIN|Ensembl=ENSCING00000018397.1|UniProtKB=H2XXL5 H2XXL5 PTHR45901:SF7 PROTEIN CBG12474 OXYGEN-REGULATED PROTEIN 1 CIOIN|Ensembl=ENSCING00000023910.1|UniProtKB=H2XRS8 H2XRS8 LOC100181613 PTHR23516:SF23 SAM (S-ADENOSYL METHIONINE) TRANSPORTER MOLYBDATE-ANION TRANSPORTER cellular anatomical entity#GO:0110165;membrane#GO:0016020 transporter#PC00227 CIOIN|Ensembl=ENSCING00000002580.3|UniProtKB=Q1RL58 Q1RL58 Ci-ZF(PARP)-2 PTHR45674:SF9 DNA LIGASE 1/3 FAMILY MEMBER DNA LIGASE 3 catalytic activity, acting on a nucleic acid#GO:0140640;ligase activity#GO:0016874;catalytic activity, acting on DNA#GO:0140097;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;DNA-templated DNA replication#GO:0006261;DNA replication#GO:0006260;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA strand elongation involved in DNA replication#GO:0006271 DNA ligase#PC00012 CIOIN|Ensembl=ENSCING00000013267.2|UniProtKB=F7BMG3 F7BMG3 PTHR46542:SF1 X-BOX BINDING PROTEIN 1 X-BOX BINDING PROTEIN 1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000012104.2|UniProtKB=F6X6I9 F6X6I9 PTHR16146:SF46 INTELECTIN INTELECTIN-1A-RELATED CIOIN|Ensembl=ENSCING00000012948.2|UniProtKB=F6RGL3 F6RGL3 PTHR19143:SF327 FIBRINOGEN/TENASCIN/ANGIOPOEITIN FI21813P1-RELATED external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 CIOIN|Ensembl=ENSCING00000000219.3|UniProtKB=F6V5P8 F6V5P8 PTHR18884:SF69 SEPTIN SEPTIN-RELATED GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824 localization#GO:0051179;cell division#GO:0051301;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;cytoskeleton-dependent cytokinesis#GO:0061640;cell cycle process#GO:0022402;cell cycle#GO:0007049;cellular process#GO:0009987;cytokinesis#GO:0000910;protein localization#GO:0008104 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;cell division site#GO:0032153;cell cortex#GO:0005938;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085 CIOIN|Ensembl=ENSCING00000019283.1|UniProtKB=H2XPQ4 H2XPQ4 LOC100176146 PTHR14154:SF2 UPF0041 BRAIN PROTEIN 44-RELATED MITOCHONDRIAL PYRUVATE CARRIER 2 CIOIN|Ensembl=ENSCING00000014782.2|UniProtKB=F6YUN5 F6YUN5 PTHR46042:SF1 DIPHTHINE METHYLTRANSFERASE DIPHTHINE METHYLTRANSFERASE hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 methyltransferase#PC00155;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000005862.3|UniProtKB=F6UG85 F6UG85 LOC100176758 PTHR13720:SF33 WD-40 REPEAT PROTEIN HELP DOMAIN-CONTAINING PROTEIN cytoskeletal protein#PC00085;microtubule or microtubule-binding cytoskeletal protein#PC00157 CIOIN|Ensembl=ENSCING00000008214.3|UniProtKB=F6PIY0 F6PIY0 PTHR10454:SF206 CASPASE CASPASE-6 cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197;hydrolase activity#GO:0016787;cysteine-type endopeptidase activity involved in apoptotic process#GO:0097153;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 regulation of biological process#GO:0050789;positive regulation of apoptotic process#GO:0043065;positive regulation of programmed cell death#GO:0043068;regulation of apoptotic process#GO:0042981;regulation of cellular process#GO:0050794;apoptotic process#GO:0006915;biological regulation#GO:0065007;cell death#GO:0008219;programmed cell death#GO:0012501;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;regulation of programmed cell death#GO:0043067;positive regulation of cellular process#GO:0048522 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 protease#PC00190;protein modifying enzyme#PC00260 Huntington disease#P00029>Caspase 6#P00809;FAS signaling pathway#P00020>Caspase6#P00596;FAS signaling pathway#P00020>Pro-Caspase6#P00607 CIOIN|Ensembl=ENSCING00000008793.3|UniProtKB=A0A1W2WG97 A0A1W2WG97 LOC100179358 PTHR48094:SF18 PROTEIN/NUCLEIC ACID DEGLYCASE DJ-1-RELATED GLUTAMINE AMIDOTRANSFERASE-LIKE CLASS 1 DOMAIN-CONTAINING PROTEIN 1 carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829;catalytic activity#GO:0003824;hydro-lyase activity#GO:0016836 organic hydroxy compound metabolic process#GO:1901615;oxoacid metabolic process#GO:0043436;small molecule catabolic process#GO:0044282;catabolic process#GO:0009056;cellular metabolic process#GO:0044237;organic substance catabolic process#GO:1901575;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;cellular catabolic process#GO:0044248;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000001170.3|UniProtKB=F6WB92 F6WB92 LOC100184601 PTHR23290:SF0 RRNA N6-ADENOSINE-METHYLTRANSFERASE METTL5 RRNA N6-ADENOSINE-METHYLTRANSFERASE METTL5 transferase activity#GO:0016740;catalytic activity#GO:0003824 CIOIN|Ensembl=ENSCING00000019939.1|UniProtKB=H2XWR5 H2XWR5 LOC100184380 PTHR15505:SF4 RIIA DOMAIN-CONTAINING PROTEIN 1 RIIA DOMAIN-CONTAINING PROTEIN 1 CIOIN|Ensembl=ENSCING00000006933.3|UniProtKB=F6VNH8 F6VNH8 nfkbp105 PTHR24169:SF28 NUCLEAR FACTOR NF-KAPPA-B PROTEIN NUCLEAR FACTOR NF-KAPPA-B P110 SUBUNIT cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 DNA-binding transcription factor#PC00218;Rel homology transcription factor#PC00252;immunoglobulin fold transcription factor#PC00251 CIOIN|Ensembl=ENSCING00000017217.2|UniProtKB=F7B2I2 F7B2I2 PTHR10513:SF15 DEOXYNUCLEOSIDE KINASE NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 10, MITOCHONDRIAL transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301 mitochondrial ATP synthesis coupled electron transport#GO:0042775;aerobic respiration#GO:0009060;cellular respiration#GO:0045333;mitochondrial electron transport, NADH to ubiquinone#GO:0006120;respiratory electron transport chain#GO:0022904;aerobic electron transport chain#GO:0019646;oxidative phosphorylation#GO:0006119;generation of precursor metabolites and energy#GO:0006091;electron transport chain#GO:0022900;ATP synthesis coupled electron transport#GO:0042773;cellular metabolic process#GO:0044237;cellular process#GO:0009987;energy derivation by oxidation of organic compounds#GO:0015980;metabolic process#GO:0008152 envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;respiratory chain complex#GO:0098803;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transporter complex#GO:1990351;oxidoreductase complex#GO:1990204;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;respirasome#GO:0070469;mitochondrial respiratory chain complex I#GO:0005747;protein-containing complex#GO:0032991;mitochondrial envelope#GO:0005740;mitochondrial respirasome#GO:0005746;transmembrane transporter complex#GO:1902495;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227;respiratory chain complex I#GO:0045271;NADH dehydrogenase complex#GO:0030964;mitochondrial protein-containing complex#GO:0098798 nucleotide kinase#PC00172 CIOIN|Ensembl=ENSCING00000008161.3|UniProtKB=F6UQM6 F6UQM6 PTHR12897:SF4 COLON CANCER-ASSOCIATED PROTEIN MIC1 REGULATOR OF MON1-CCZ1 COMPLEX regulation of biological process#GO:0050789;regulation of catabolic process#GO:0009894;regulation of cellular process#GO:0050794;regulation of autophagy#GO:0010506;biological regulation#GO:0065007;regulation of cellular catabolic process#GO:0031329;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 bounding membrane of organelle#GO:0098588;lytic vacuole membrane#GO:0098852;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuolar membrane#GO:0005774;late endosome membrane#GO:0031902;vacuole#GO:0005773;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;intracellular protein-containing complex#GO:0140535;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endosome membrane#GO:0010008;lytic vacuole#GO:0000323;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;lysosomal membrane#GO:0005765;protein-containing complex#GO:0032991;lysosome#GO:0005764;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;guanyl-nucleotide exchange factor complex#GO:0032045;cytoplasmic vesicle membrane#GO:0030659;late endosome#GO:0005770 CIOIN|Ensembl=ENSCING00000013996.3|UniProtKB=F6VII3 F6VII3 PTHR14428:SF5 NUCLEOLAR COMPLEX PROTEIN 3 NUCLEOLAR COMPLEX PROTEIN 3 HOMOLOG protein-containing complex binding#GO:0044877;binding#GO:0005488;chromatin binding#GO:0003682 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;DNA-templated DNA replication#GO:0006261;DNA replication#GO:0006260;DNA replication initiation#GO:0006270;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000003546.3|UniProtKB=K9J6P5 K9J6P5 LOC100175075 PTHR23264:SF19 NUCLEOTIDE-BINDING PROTEIN NBP35 YEAST -RELATED CYTOSOLIC FE-S CLUSTER ASSEMBLY FACTOR NUBP2 small molecule binding#GO:0036094;binding#GO:0005488;iron-sulfur cluster binding#GO:0051536 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;iron-sulfur cluster assembly#GO:0016226;cellular component organization#GO:0016043;cellular process#GO:0009987 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000014428.2|UniProtKB=F6WY47 F6WY47 PTHR44040:SF1 RETINOBLASTOMA-BINDING PROTEIN 5 RETINOBLASTOMA-BINDING PROTEIN 5 membrane-enclosed lumen#GO:0031974;histone methyltransferase complex#GO:0035097;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;methyltransferase complex#GO:0034708;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;Set1C/COMPASS complex#GO:0048188;nuclear protein-containing complex#GO:0140513 CIOIN|Ensembl=ENSCING00000007877.3|UniProtKB=F6TGV4 F6TGV4 LOC100178029 PTHR12895:SF9 DYMECLIN DYMECLIN endomembrane system organization#GO:0010256;cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;cellular process#GO:0009987;Golgi organization#GO:0007030;organelle organization#GO:0006996 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000007354.3|UniProtKB=F6VZ84 F6VZ84 LOC100183021 PTHR12103:SF15 5'-NUCLEOTIDASE DOMAIN-CONTAINING CYTOSOLIC PURINE 5'-NUCLEOTIDASE hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;5'-nucleotidase activity#GO:0008253;catalytic activity#GO:0003824;nucleotidase activity#GO:0008252;phosphoric ester hydrolase activity#GO:0042578 nucleotide phosphatase#PC00173;phosphatase#PC00181;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000006061.3|UniProtKB=F6ZGU5 F6ZGU5 PTHR23161:SF2 PROTEIN CIP2A PROTEIN CIP2A CIOIN|Ensembl=ENSCING00000024552.1|UniProtKB=H2XXD0 H2XXD0 LOC100181275 PTHR11132:SF238 SOLUTE CARRIER FAMILY 35 SOLUTE CARRIER FAMILY 35 MEMBER C2 secondary active transmembrane transporter activity#GO:0015291;antiporter activity#GO:0015297;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 localization#GO:0051179;organic substance transport#GO:0071702;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;organic anion transport#GO:0015711;nucleobase-containing compound transport#GO:0015931;nucleotide-sugar transmembrane transport#GO:0015780;transport#GO:0006810;nitrogen compound transport#GO:0071705;cellular process#GO:0009987;carbohydrate derivative transport#GO:1901264 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cis-Golgi network#GO:0005801;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000022737.1|UniProtKB=H2XWT4 H2XWT4 LOC100175927 PTHR24342:SF14 SERINE/THREONINE-PROTEIN KINASE 17 DEATH-ASSOCIATED PROTEIN KINASE DAPK-1 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 positive regulation of apoptotic process#GO:0043065;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of apoptotic process#GO:0042981;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;positive regulation of programmed cell death#GO:0043068;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;intracellular signal transduction#GO:0035556;signaling#GO:0023052;positive regulation of biological process#GO:0048518;regulation of programmed cell death#GO:0043067 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000008212.2|UniProtKB=F6PIX4 F6PIX4 PTHR22950:SF702 AMINO ACID TRANSPORTER AMINO ACID TRANSPORTER PROTEIN L-amino acid transmembrane transporter activity#GO:0015179;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;amino acid transmembrane transporter activity#GO:0015171;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215;organic acid transmembrane transporter activity#GO:0005342 localization#GO:0051179;organic substance transport#GO:0071702;amino acid transmembrane transport#GO:0003333;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;amino acid transport#GO:0006865;organic anion transport#GO:0015711;organic acid transport#GO:0015849;transport#GO:0006810;nitrogen compound transport#GO:0071705;organic acid transmembrane transport#GO:1903825;carboxylic acid transport#GO:0046942;cellular process#GO:0009987;carboxylic acid transmembrane transport#GO:1905039 cellular anatomical entity#GO:0110165;membrane#GO:0016020 amino acid transporter#PC00046;transporter#PC00227 CIOIN|Ensembl=ENSCING00000001685.3|UniProtKB=F6UK51 F6UK51 LOC100181511 PTHR11165:SF24 SKP1 S-PHASE KINASE-ASSOCIATED PROTEIN 1 cullin family protein binding#GO:0097602;protein binding#GO:0005515;binding#GO:0005488 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000022845.1|UniProtKB=H2XSQ2 H2XSQ2 PTHR43941:SF14 STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 2 PH DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000014502.2|UniProtKB=F6QDH2 F6QDH2 PTHR43986:SF1 ELONGATION FACTOR 1-GAMMA ELONGATION FACTOR 1-GAMMA macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;translation#GO:0006412;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;translational elongation#GO:0006414;amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000012732.2|UniProtKB=F7A9Q6 F7A9Q6 PTHR11375:SF0 ACIDIC LEUCINE-RICH NUCLEAR PHOSPHOPROTEIN 32 ACIDIC LEUCINE-RICH NUCLEAR PHOSPHOPROTEIN 32 FAMILY MEMBER A protein binding#GO:0005515;binding#GO:0005488;histone binding#GO:0042393 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 CIOIN|Ensembl=ENSCING00000000903.3|UniProtKB=F6U1C4 F6U1C4 PTHR10024:SF344 SYNAPTOTAGMIN SYNAPTOTAGMIN-7 cation binding#GO:0043169;small molecule binding#GO:0036094;binding#GO:0005488;phosphatidylserine binding#GO:0001786;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;protein binding#GO:0005515;clathrin binding#GO:0030276;lipid binding#GO:0008289;ion binding#GO:0043167;phospholipid binding#GO:0005543;SNARE binding#GO:0000149 vesicle fusion#GO:0006906;cellular localization#GO:0051641;synaptic vesicle cycle#GO:0099504;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;transport#GO:0006810;regulated exocytosis#GO:0045055;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;secretion#GO:0046903;neurotransmitter transport#GO:0006836;synaptic signaling#GO:0099536;signal release#GO:0023061;vesicle organization#GO:0016050;calcium-ion regulated exocytosis#GO:0017156;signaling#GO:0023052;cell-cell signaling#GO:0007267;synaptic vesicle exocytosis#GO:0016079;organelle fusion#GO:0048284;secretion by cell#GO:0032940;neurotransmitter secretion#GO:0007269;trans-synaptic signaling#GO:0099537;vesicle-mediated transport#GO:0016192;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;membrane fusion#GO:0061025;signal release from synapse#GO:0099643;exocytosis#GO:0006887;organelle organization#GO:0006996;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;export from cell#GO:0140352;vesicle-mediated transport in synapse#GO:0099003 synapse#GO:0045202;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;axon#GO:0030424;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;neuron projection#GO:0043005;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;transport vesicle#GO:0030133;cell projection#GO:0042995;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 membrane trafficking regulatory protein#PC00151 Synaptic vesicle trafficking#P05734>Synaptotagmin#P05769 CIOIN|Ensembl=ENSCING00000012613.2|UniProtKB=F6XEI7 F6XEI7 PTHR11929:SF145 ALPHA- 1,3 -FUCOSYLTRANSFERASE ALPHA-(1,3)-FUCOSYLTRANSFERASE FUT-1 transferase activity#GO:0016740;fucosyltransferase activity#GO:0008417;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 glycosylation#GO:0070085;metabolic process#GO:0008152 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000024829.1|UniProtKB=H2XQ42 H2XQ42 PTHR22883:SF40 ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN PALMITOYLTRANSFERASE palmitoyltransferase activity#GO:0016409;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular localization#GO:0051641;macromolecule localization#GO:0033036;macromolecule modification#GO:0043412;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;biosynthetic process#GO:0009058;establishment of protein localization#GO:0045184;establishment of protein localization to membrane#GO:0090150;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;protein palmitoylation#GO:0018345;protein metabolic process#GO:0019538;protein lipidation#GO:0006497;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;localization within membrane#GO:0051668;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein localization to membrane#GO:0072657;organonitrogen compound biosynthetic process#GO:1901566;protein targeting#GO:0006605;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;protein acylation#GO:0043543;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;lipoprotein biosynthetic process#GO:0042158;protein localization#GO:0008104;primary metabolic process#GO:0044238;localization#GO:0051179;protein targeting to membrane#GO:0006612;cellular macromolecule localization#GO:0070727;lipoprotein metabolic process#GO:0042157 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000010894.3|UniProtKB=F6WIE6 F6WIE6 LOC100179345 PTHR31109:SF2 PROTEIN FAM207A RIBOSOME BIOGENESIS PROTEIN SLX9 HOMOLOG CIOIN|Ensembl=ENSCING00000004198.3|UniProtKB=F7AM07 F7AM07 PTHR23147:SF22 SERINE/ARGININE RICH SPLICING FACTOR SERINE_ARGININE-RICH SPLICING FACTOR 2 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;nuclear speck#GO:0016607;organelle#GO:0043226;nuclear body#GO:0016604;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA splicing factor#PC00148;RNA processing factor#PC00147;RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000006371.3|UniProtKB=F6RKM9 F6RKM9 PTHR11630:SF43 DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER DNA REPLICATION LICENSING FACTOR MCM6 ATP-dependent activity, acting on DNA#GO:0008094;nucleic acid binding#GO:0003676;3'-5' DNA helicase activity#GO:0043138;helicase activity#GO:0004386;ATP-dependent activity#GO:0140657;single-stranded DNA binding#GO:0003697;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;catalytic activity, acting on a nucleic acid#GO:0140640;DNA helicase activity#GO:0003678;catalytic activity, acting on DNA#GO:0140097;single-stranded DNA helicase activity#GO:0017116 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;double-strand break repair#GO:0006302;cell cycle process#GO:0022402;nucleobase-containing compound metabolic process#GO:0006139;mitotic cell cycle process#GO:1903047;DNA geometric change#GO:0032392;DNA damage response#GO:0006974;mitotic cell cycle#GO:0000278;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;recombinational repair#GO:0000725;DNA duplex unwinding#GO:0032508;DNA-templated DNA replication#GO:0006261;cell cycle DNA replication#GO:0044786;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nuclear DNA replication#GO:0033260;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;DNA unwinding involved in DNA replication#GO:0006268;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;double-strand break repair via homologous recombination#GO:0000724;cellular process#GO:0009987;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;DNA conformation change#GO:0071103;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;double-strand break repair via break-induced replication#GO:0000727;organelle organization#GO:0006996;chromosome organization#GO:0051276;mitotic DNA replication#GO:1902969;cell cycle#GO:0007049;cellular response to stress#GO:0033554;DNA replication#GO:0006260;DNA metabolic process#GO:0006259 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;MCM complex#GO:0042555;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA metabolism protein#PC00009 CIOIN|Ensembl=ENSCING00000008703.3|UniProtKB=F6WD89 F6WD89 groucho2 PTHR10814:SF21 TRANSDUCIN-LIKE ENHANCER PROTEIN PROTEIN GROUCHO molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714;protein-macromolecule adaptor activity#GO:0030674 regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;negative regulation of response to stimulus#GO:0048585;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;regulation of canonical Wnt signaling pathway#GO:0060828;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;regulation of Wnt signaling pathway#GO:0030111;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of canonical Wnt signaling pathway#GO:0090090;negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transcription cofactor#PC00217 Wnt signaling pathway#P00057>Transducin-like Enhance of Split 1-3#P01436 CIOIN|Ensembl=ENSCING00000024258.1|UniProtKB=H2XZX0 H2XZX0 PTHR19444:SF13 UNC-93 RELATED PROTEIN UNC-93 HOMOLOG A membrane-bound signaling molecule#PC00152 CIOIN|Ensembl=ENSCING00000001480.3|UniProtKB=F6TI69 F6TI69 LOC100186491 PTHR12560:SF58 LONGEVITY ASSURANCE FACTOR 1 LAG1 CERAMIDE SYNTHASE 1 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity#GO:0003824;N-acyltransferase activity#GO:0016410 lipid metabolic process#GO:0006629;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;membrane lipid biosynthetic process#GO:0046467;sphingolipid metabolic process#GO:0006665;ceramide metabolic process#GO:0006672;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;membrane lipid metabolic process#GO:0006643;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;ceramide biosynthetic process#GO:0046513;cellular lipid metabolic process#GO:0044255;amide metabolic process#GO:0043603;sphingolipid biosynthetic process#GO:0030148;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 transferase#PC00220;metabolite interconversion enzyme#PC00262 TGF-beta signaling pathway#P00052>TGFbeta#P01286 CIOIN|Ensembl=ENSCING00000004567.3|UniProtKB=F6XCY9 F6XCY9 LOC100180952 PTHR22091:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 77 COILED-COIL DOMAIN-CONTAINING PROTEIN 77 CIOIN|Ensembl=ENSCING00000008904.3|UniProtKB=F6QBH7 F6QBH7 LOC100177154 PTHR22950:SF652 AMINO ACID TRANSPORTER TRANSMEMBRANE AMINO ACID TRANSPORTER FAMILY PROTEIN L-amino acid transmembrane transporter activity#GO:0015179;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;amino acid transmembrane transporter activity#GO:0015171;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215;organic acid transmembrane transporter activity#GO:0005342 localization#GO:0051179;organic substance transport#GO:0071702;amino acid transmembrane transport#GO:0003333;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;amino acid transport#GO:0006865;organic anion transport#GO:0015711;organic acid transport#GO:0015849;transport#GO:0006810;nitrogen compound transport#GO:0071705;organic acid transmembrane transport#GO:1903825;carboxylic acid transport#GO:0046942;cellular process#GO:0009987;carboxylic acid transmembrane transport#GO:1905039 cellular anatomical entity#GO:0110165;membrane#GO:0016020 amino acid transporter#PC00046;transporter#PC00227 CIOIN|Ensembl=ENSCING00000009547.3|UniProtKB=F6U8M1 F6U8M1 LOC100175173 PTHR12943:SF27 HOMOCYSTEINE-RESPONSIVE ENDOPLASMIC RETICULUM-RESIDENT UNIQUITIN-LIKE DOMAIN HERPUD PROTEIN FAMILY MEMBER HOMOCYSTEINE-INDUCED ENDOPLASMIC RETICULUM PROTEIN, ISOFORM A response to organic substance#GO:0010033;signal transduction#GO:0007165;endoplasmic reticulum unfolded protein response#GO:0030968;cellular response to stimulus#GO:0051716;response to endoplasmic reticulum stress#GO:0034976;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to topologically incorrect protein#GO:0035967;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;response to unfolded protein#GO:0006986;cellular response to unfolded protein#GO:0034620;response to topologically incorrect protein#GO:0035966;biological regulation#GO:0065007;cellular response to stress#GO:0033554;signaling#GO:0023052 CIOIN|Ensembl=ENSCING00000016204.2|UniProtKB=F6ZS71 F6ZS71 PTHR12356:SF19 NUCLEAR MOVEMENT PROTEIN NUDC NUDC DOMAIN-CONTAINING PROTEIN 3 protein binding#GO:0005515;unfolded protein binding#GO:0051082;binding#GO:0005488 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein folding#GO:0006457;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;microtubule or microtubule-binding cytoskeletal protein#PC00157 CIOIN|Ensembl=ENSCING00000014179.2|UniProtKB=F7A7S2 F7A7S2 LOC101242363 PTHR10036:SF3 CD59 GLYCOPROTEIN PROTEIN SLEEPLESS-RELATED CIOIN|Ensembl=ENSCING00000006810.3|UniProtKB=F6UMM5 F6UMM5 LOC100184104 PTHR10539:SF0 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 13 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 13 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 peptidase complex#GO:1905368;proteasome accessory complex#GO:0022624;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;proteasome regulatory particle#GO:0005838;catalytic complex#GO:1902494;proteasome regulatory particle, lid subcomplex#GO:0008541;proteasome complex#GO:0000502;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endopeptidase complex#GO:1905369;membrane-bounded organelle#GO:0043227 protease#PC00190;protein modifying enzyme#PC00260 Parkinson disease#P00049>19S proteasome#P01209;Ubiquitin proteasome pathway#P00060>26S proteasome#P01489;Cell cycle#P00013>Proteasome#P00480 CIOIN|Ensembl=ENSCING00000003119.3|UniProtKB=F6RD45 F6RD45 LOC100187074 PTHR46379:SF1 ZINC FINGER MYND DOMAIN-CONTAINING ZINC FINGER MYND DOMAIN-CONTAINING PROTEIN 11 protein binding#GO:0005515;methylated histone binding#GO:0035064;histone binding#GO:0042393;binding#GO:0005488;modification-dependent protein binding#GO:0140030 regulation of DNA-templated transcription elongation#GO:0032784;regulation of transcription elongation by RNA polymerase II#GO:0034243;regulation of cell communication#GO:0010646;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of signaling#GO:0023051;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transcription cofactor#PC00217 CIOIN|Ensembl=ENSCING00000001135.3|UniProtKB=F6ZD22 F6ZD22 PTHR21014:SF6 PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE 4-PHOSPHATASE PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE 4-PHOSPHATASE hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 phospholipid dephosphorylation#GO:0046839;lipid metabolic process#GO:0006629;phosphatidylinositol dephosphorylation#GO:0046856;cellular metabolic process#GO:0044237;phosphatidylinositol metabolic process#GO:0046488;glycerophospholipid metabolic process#GO:0006650;lipid modification#GO:0030258;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;dephosphorylation#GO:0016311;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 bounding membrane of organelle#GO:0098588;lytic vacuole membrane#GO:0098852;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuolar membrane#GO:0005774;late endosome membrane#GO:0031902;vacuole#GO:0005773;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endosome membrane#GO:0010008;lytic vacuole#GO:0000323;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;lysosomal membrane#GO:0005765;lysosome#GO:0005764;endomembrane system#GO:0012505;phagocytic vesicle#GO:0045335;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endocytic vesicle#GO:0030139;cytoplasmic vesicle membrane#GO:0030659;late endosome#GO:0005770;plasma membrane#GO:0005886 phosphatase#PC00181;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000009488.3|UniProtKB=F6Y9G9 F6Y9G9 PTHR11358:SF26 ARGINASE/AGMATINASE GUANIDINO ACID HYDROLASE, MITOCHONDRIAL hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;catalytic activity#GO:0003824 amine metabolic process#GO:0009308;oxoacid metabolic process#GO:0043436;biogenic amine metabolic process#GO:0006576;arginine metabolic process#GO:0006525;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;polyamine metabolic process#GO:0006595;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;alpha-amino acid metabolic process#GO:1901605;polyamine biosynthetic process#GO:0006596;carboxylic acid metabolic process#GO:0019752;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000022288.1|UniProtKB=H2XJZ6 H2XJZ6 LOC113474223 PTHR36978:SF4 P-LOOP CONTAINING NUCLEOTIDE TRIPHOSPHATE HYDROLASE P-LOOP CONTAINING NUCLEOSIDE TRIPHOSPHATE HYDROLASE PROTEIN metabolite interconversion enzyme#PC00262;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000000933.3|UniProtKB=F6TDV1 F6TDV1 LOC100183338 PTHR23325:SF1 SERUM RESPONSE FACTOR-BINDING SERUM RESPONSE FACTOR-BINDING PROTEIN 1 RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000005584.3|UniProtKB=F6U441 F6U441 PTHR14885:SF1 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 43-RELATED CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 43 organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cell projection organization#GO:0030030;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031 axoneme#GO:0005930;cytoplasmic region#GO:0099568;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;plasma membrane bounded cell projection cytoplasm#GO:0032838;ciliary plasm#GO:0097014;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cytoskeleton#GO:0005856;cilium#GO:0005929 CIOIN|Ensembl=ENSCING00000000360.3|UniProtKB=F6U7K8 F6U7K8 PTHR24416:SF564 TYROSINE-PROTEIN KINASE RECEPTOR MACROPHAGE-STIMULATING PROTEIN RECEPTOR signaling receptor activity#GO:0038023;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;molecular transducer activity#GO:0060089;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672;transmembrane signaling receptor activity#GO:0004888 signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;positive regulation of cellular metabolic process#GO:0031325;developmental process#GO:0032502;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;nervous system development#GO:0007399;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;system development#GO:0048731;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;regulation of molecular function#GO:0065009;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;positive regulation of phosphorylation#GO:0042327;cellular response to stimulus#GO:0051716;positive regulation of catalytic activity#GO:0043085;multicellular organism development#GO:0007275;positive regulation of phosphorus metabolic process#GO:0010562;cell communication#GO:0007154;cell motility#GO:0048870;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphate metabolic process#GO:0045937;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;multicellular organismal process#GO:0032501;cell migration#GO:0016477;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 receptor complex#GO:0043235;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 CIOIN|Ensembl=ENSCING00000008150.3|UniProtKB=F6VFN8 F6VFN8 PTHR10582:SF33 TRANSIENT RECEPTOR POTENTIAL ION CHANNEL PROTEIN TRANSIENT RECEPTOR POTENTIAL CHANNEL PYREXIA calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;metal ion transmembrane transporter activity#GO:0046873;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;monoatomic ion channel activity#GO:0005216;inorganic cation transmembrane transporter activity#GO:0022890;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;calcium ion transmembrane transport#GO:0070588;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;calcium ion transport#GO:0006816;localization#GO:0051179;calcium ion import#GO:0070509;import across plasma membrane#GO:0098739;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;calcium ion transmembrane import into cytosol#GO:0097553;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;import into cell#GO:0098657 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 CIOIN|Ensembl=ENSCING00000007727.3|UniProtKB=F6ZIF8 F6ZIF8 PTHR10252:SF8 HISTONE-LIKE TRANSCRIPTION FACTOR CCAAT-RELATED NUCLEAR TRANSCRIPTION FACTOR Y SUBUNIT GAMMA sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218 Gonadotropin-releasing hormone receptor pathway#P06664>NF-Y#P06742 CIOIN|Ensembl=ENSCING00000016600.2|UniProtKB=F6UQH1 F6UQH1 PTHR23503:SF8 SOLUTE CARRIER FAMILY 2 FACILITATED GLUCOSE TRANSPORTER PROTEIN 1 transmembrane transporter activity#GO:0022857;sugar transmembrane transporter activity#GO:0051119;transporter activity#GO:0005215;carbohydrate transmembrane transporter activity#GO:0015144 localization#GO:0051179;organic substance transport#GO:0071702;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810;cellular process#GO:0009987;carbohydrate transmembrane transport#GO:0034219;carbohydrate transport#GO:0008643 cellular anatomical entity#GO:0110165;membrane#GO:0016020 secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000007884.3|UniProtKB=F6SUC2 F6SUC2 LOC100177272 PTHR19376:SF37 DNA-DIRECTED RNA POLYMERASE DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1 catalytic activity, acting on RNA#GO:0140098;5'-3' RNA polymerase activity#GO:0034062;transferase activity#GO:0016740;DNA-directed 5'-3' RNA polymerase activity#GO:0003899;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;RNA polymerase activity#GO:0097747;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring phosphorus-containing groups#GO:0016772;RNA polymerase II activity#GO:0001055 membrane-enclosed lumen#GO:0031974;RNA polymerase II, core complex#GO:0005665;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;DNA-directed RNA polymerase complex#GO:0000428;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695;RNA polymerase II, holoenzyme#GO:0016591;RNA polymerase complex#GO:0030880;protein-containing complex#GO:0032991;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 RNA metabolism protein#PC00031;DNA-directed RNA polymerase#PC00019 CIOIN|Ensembl=ENSCING00000019988.1|UniProtKB=H2Y071 H2Y071 PTHR11339:SF393 EXTRACELLULAR MATRIX GLYCOPROTEIN RELATED VWFD DOMAIN-CONTAINING PROTEIN external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 extracellular matrix protein#PC00102 CIOIN|Ensembl=ENSCING00000008846.3|UniProtKB=F6R4D8 F6R4D8 PTHR22957:SF333 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER 25 nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 regulation of molecular function#GO:0065009;regulation of GTPase activity#GO:0043087;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;activation of GTPase activity#GO:0090630;biological regulation#GO:0065007;positive regulation of molecular function#GO:0044093;regulation of hydrolase activity#GO:0051336;regulation of catalytic activity#GO:0050790;positive regulation of hydrolase activity#GO:0051345 GTPase-activating protein#PC00257 CIOIN|Ensembl=ENSCING00000000937.3|UniProtKB=F6TDH1 F6TDH1 LOC100180734 PTHR14110:SF0 MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM22 MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM22 signal sequence binding#GO:0005048;protein transmembrane transporter activity#GO:0008320;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277 cellular localization#GO:0051641;protein insertion into mitochondrial inner membrane#GO:0045039;macromolecule localization#GO:0033036;membrane organization#GO:0061024;transport#GO:0006810;nitrogen compound transport#GO:0071705;establishment of protein localization#GO:0045184;organic substance transport#GO:0071702;establishment of protein localization to membrane#GO:0090150;establishment of localization#GO:0051234;protein targeting to mitochondrion#GO:0006626;mitochondrion organization#GO:0007005;protein localization to organelle#GO:0033365;localization within membrane#GO:0051668;protein localization to membrane#GO:0072657;protein targeting#GO:0006605;establishment of protein localization to organelle#GO:0072594;cellular component organization#GO:0016043;cellular process#GO:0009987;protein localization to mitochondrion#GO:0070585;protein localization#GO:0008104;inner mitochondrial membrane organization#GO:0007007;mitochondrial transport#GO:0006839;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;organelle organization#GO:0006996;establishment of protein localization to mitochondrion#GO:0072655;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;mitochondrial membrane organization#GO:0007006 envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial envelope#GO:0005740;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227;mitochondrial protein-containing complex#GO:0098798 transporter#PC00227 CIOIN|Ensembl=ENSCING00000002905.3|UniProtKB=F6SCV9 F6SCV9 LOC100183627 PTHR35991:SF1 CA-RESPONSIVE PROTEIN CA-RESPONSIVE PROTEIN CIOIN|Ensembl=ENSCING00000001547.3|UniProtKB=F6YKR1 F6YKR1 PTHR11361:SF20 DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER MUTS PROTEIN HOMOLOG 5 nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;homologous chromosome segregation#GO:0045143;nuclear division#GO:0000280;cell cycle process#GO:0022402;nucleobase-containing compound metabolic process#GO:0006139;chromosome segregation#GO:0007059;reciprocal homologous recombination#GO:0140527;chromosome organization involved in meiotic cell cycle#GO:0070192;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;meiotic cell cycle process#GO:1903046;meiosis I cell cycle process#GO:0061982;reproductive process#GO:0022414;reciprocal meiotic recombination#GO:0007131;meiosis I#GO:0007127;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;nuclear chromosome segregation#GO:0098813;macromolecule metabolic process#GO:0043170;meiotic cell cycle#GO:0051321;homologous chromosome pairing at meiosis#GO:0007129;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;meiotic chromosome segregation#GO:0045132;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;reproduction#GO:0000003;meiotic nuclear division#GO:0140013;organelle organization#GO:0006996;chromosome organization#GO:0051276;sexual reproduction#GO:0019953;cell cycle#GO:0007049;organelle fission#GO:0048285;homologous recombination#GO:0035825;DNA metabolic process#GO:0006259 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA metabolism protein#PC00009 CIOIN|Ensembl=ENSCING00000003389.4|UniProtKB=H2XJF2 H2XJF2 PTHR10048:SF7 PHOSPHATIDYLINOSITOL KINASE PHOSPHATIDYLINOSITOL 3-KINASE CATALYTIC SUBUNIT TYPE 3 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;catalytic activity#GO:0003824;lipid kinase activity#GO:0001727 lipid metabolic process#GO:0006629;cellular component biogenesis#GO:0044085;signal transduction#GO:0007165;phospholipid biosynthetic process#GO:0008654;macroautophagy#GO:0016236;phosphatidylinositol biosynthetic process#GO:0006661;organophosphate biosynthetic process#GO:0090407;transport#GO:0006810;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;lipid biosynthetic process#GO:0008610;phosphatidylinositol phosphate biosynthetic process#GO:0046854;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;glycerolipid metabolic process#GO:0046486;establishment of localization#GO:0051234;catabolic process#GO:0009056;intracellular signal transduction#GO:0035556;signaling#GO:0023052;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular component assembly#GO:0022607;cellular response to stimulus#GO:0051716;glycerolipid biosynthetic process#GO:0045017;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cell communication#GO:0007154;glycerophospholipid metabolic process#GO:0006650;phosphatidylinositol metabolic process#GO:0046488;cellular component organization#GO:0016043;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;glycerophospholipid biosynthetic process#GO:0046474;biological regulation#GO:0065007;autophagosome assembly#GO:0000045;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;autophagy#GO:0006914;import into cell#GO:0098657 membrane protein complex#GO:0098796;endosome#GO:0005768;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;phosphatidylinositol 3-kinase complex#GO:0005942;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;phosphatidylinositol 3-kinase complex, class III#GO:0035032;vesicle#GO:0031982;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;extrinsic component of membrane#GO:0019898;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;phagophore assembly site#GO:0000407;endomembrane system#GO:0012505;peroxisome#GO:0005777;microbody#GO:0042579;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410 kinase#PC00137 PDGF signaling pathway#P00047>PI3K#P01168;T cell activation#P00053>PI3K#P01322;Hypoxia response via HIF activation#P00030>PI3K#P00823;Angiogenesis#P00005>PI3K#P00236;EGF receptor signaling pathway#P00018>PI3K#P00557;VEGF signaling pathway#P00056>PI3K#P01413;FGF signaling pathway#P00021>PI3K#P00640;Ras Pathway#P04393>PI3K#P04567;p53 pathway feedback loops 2#P04398>PI3K#P04661;p53 pathway#P00059>PI3K#P04609;Endothelin signaling pathway#P00019>PI3K#P00577;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>PI3K#P00900;Integrin signalling pathway#P00034>PI3K#P00936 CIOIN|Ensembl=ENSCING00000007708.3|UniProtKB=F6WK69 F6WK69 PTHR46200:SF1 GATOR COMPLEX PROTEIN WDR24 GATOR COMPLEX PROTEIN WDR24 regulation of cell communication#GO:0010646;positive regulation of TORC1 signaling#GO:1904263;regulation of TORC1 signaling#GO:1903432;regulation of catabolic process#GO:0009894;positive regulation of signal transduction#GO:0009967;regulation of autophagy#GO:0010506;positive regulation of cellular metabolic process#GO:0031325;regulation of signaling#GO:0023051;positive regulation of cellular catabolic process#GO:0031331;regulation of macroautophagy#GO:0016241;regulation of cellular catabolic process#GO:0031329;regulation of intracellular signal transduction#GO:1902531;regulation of TOR signaling#GO:0032006;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of macroautophagy#GO:0016239;positive regulation of metabolic process#GO:0009893;regulation of cellular process#GO:0050794;positive regulation of TOR signaling#GO:0032008;regulation of signal transduction#GO:0009966;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;positive regulation of catabolic process#GO:0009896;positive regulation of autophagy#GO:0010508;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 bounding membrane of organelle#GO:0098588;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;Seh1-associated complex#GO:0035859;intracellular membrane-bounded organelle#GO:0043231;vacuolar membrane#GO:0005774;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000023500.1|UniProtKB=H2XYU1 H2XYU1 PTHR22880:SF225 FALZ-RELATED BROMODOMAIN-CONTAINING PROTEINS BROMODOMAIN-CONTAINING PROTEIN BET-1-RELATED protein binding#GO:0005515;histone binding#GO:0042393;binding#GO:0005488;modification-dependent protein binding#GO:0140030 protein-DNA complex organization#GO:0071824;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;cellular component organization#GO:0016043;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;protein-containing complex organization#GO:0043933;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;chromatin remodeling#GO:0006338;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 CIOIN|Ensembl=ENSCING00000014144.2|UniProtKB=Q7YT73 Q7YT73 rcl1 PTHR24072:SF359 RHO FAMILY GTPASE RAS-RELATED PROTEIN RAC1-RELATED GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;enzyme binding#GO:0019899;ribonucleoside triphosphate phosphatase activity#GO:0017111;kinase binding#GO:0019900;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;protein kinase binding#GO:0019901;anion binding#GO:0043168;ion binding#GO:0043167 establishment or maintenance of cell polarity#GO:0007163;regulation of anatomical structure morphogenesis#GO:0022603;regulation of organelle organization#GO:0033043;regulation of cellular component organization#GO:0051128;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of cytoskeleton organization#GO:0051493;regulation of cell shape#GO:0008360;regulation of biological quality#GO:0065008;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;cortical cytoskeleton organization#GO:0030865;biological regulation#GO:0065007;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;regulation of actin filament-based process#GO:0032970 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 small GTPase#PC00208 T cell activation#P00053>rac#P01324;Huntington disease#P00029>Rac#P00775;Cytoskeletal regulation by Rho GTPase#P00016>Rac#P00523;EGF receptor signaling pathway#P00018>Rac#P00564;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Cdc42#P00834;Ras Pathway#P04393>Rac#P04559;Axon guidance mediated by netrin#P00009>Rac#P00366;Integrin signalling pathway#P00034>Rac#P00927;Axon guidance mediated by Slit/Robo#P00008>Rac#P00354;FGF signaling pathway#P00021>Rac#P00645 CIOIN|Ensembl=ENSCING00000018968.1|UniProtKB=H2XY72 H2XY72 LOC100185351 PTHR13481:SF0 SREBP REGULATING GENE PROTEIN SREBP REGULATING GENE PROTEIN CIOIN|Ensembl=ENSCING00000003391.3|UniProtKB=F6ZNE7 F6ZNE7 tbx15_18_22 PTHR11267:SF207 T-BOX PROTEIN-RELATED OVER COMPENSATING MALES, ISOFORM A sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cell fate commitment#GO:0045165;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;cell fate specification#GO:0001708;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;Rel homology transcription factor#PC00252;immunoglobulin fold transcription factor#PC00251 CIOIN|Ensembl=ENSCING00000007873.3|UniProtKB=F6TGY3 F6TGY3 PTHR14758:SF1 AGAP005440-PA CENTROSOME-ASSOCIATED FAM110 C-TERMINAL DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000004126.3|UniProtKB=Q1RLA7 Q1RLA7 Ci-ZF(FYVE)-5 PTHR24118:SF82 POTE ANKYRIN DOMAIN RABANKYRIN-5 membrane traffic protein#PC00150 CIOIN|Ensembl=ENSCING00000018403.1|UniProtKB=H2XU13 H2XU13 PTHR11739:SF8 CITRATE SYNTHASE CITRATE SYNTHASE, MITOCHONDRIAL transferase activity#GO:0016740;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824 aerobic respiration#GO:0009060;cellular respiration#GO:0045333;generation of precursor metabolites and energy#GO:0006091;cellular metabolic process#GO:0044237;cellular process#GO:0009987;carbohydrate metabolic process#GO:0005975;energy derivation by oxidation of organic compounds#GO:0015980;tricarboxylic acid cycle#GO:0006099;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 Pyruvate metabolism#P02772>Citrate Synthetase#P03141;TCA cycle#P00051>Citrate Synthase#P01267 CIOIN|Ensembl=ENSCING00000018686.1|UniProtKB=H2XUT2 H2XUT2 PTHR12625:SF0 LIPOCALIN-1 INTERACTING MEMBRANE RECEPTOR LIMR PROTEIN LILIPOD signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 CIOIN|Ensembl=ENSCING00000020031.1|UniProtKB=H2XW02 H2XW02 PTHR12777:SF0 SMALL NUCLEAR RIBONUCLEOPROTEIN SM D2 SMALL NUCLEAR RIBONUCLEOPROTEIN SM D2 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;RNA processing#GO:0006396;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;protein-RNA complex assembly#GO:0022618;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;spliceosomal snRNP assembly#GO:0000387;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;protein-containing complex organization#GO:0043933;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;ribonucleoprotein complex biogenesis#GO:0022613;mRNA processing#GO:0006397;protein-RNA complex organization#GO:0071826;RNA splicing, via transesterification reactions#GO:0000375 catalytic step 2 spliceosome#GO:0071013;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;U4/U6 x U5 tri-snRNP complex#GO:0046540;U1 snRNP#GO:0005685;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;U5 snRNP#GO:0005682;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;spliceosomal snRNP complex#GO:0097525;small nuclear ribonucleoprotein complex#GO:0030532;pICln-Sm protein complex#GO:0034715;protein-containing complex#GO:0032991;U2 snRNP#GO:0005686;spliceosomal tri-snRNP complex#GO:0097526;precatalytic spliceosome#GO:0071011;membrane-bounded organelle#GO:0043227;Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513 RNA processing factor#PC00147;RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000005709.3|UniProtKB=F6WQ08 F6WQ08 PTHR24349:SF179 SERINE/THREONINE-PROTEIN KINASE MAP KINASE-ACTIVATED PROTEIN KINASE 5 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;enzyme binding#GO:0019899;protein binding#GO:0005515;calmodulin binding#GO:0005516;protein kinase binding#GO:0019901;mitogen-activated protein kinase binding#GO:0051019;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;kinase binding#GO:0019900;protein kinase activity#GO:0004672 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;small GTPase-mediated signal transduction#GO:0007264;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;Ras protein signal transduction#GO:0007265;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular process#GO:0009987;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000023383.1|UniProtKB=H2Y1I5 H2Y1I5 PTHR10048:SF14 PHOSPHATIDYLINOSITOL KINASE LD28067P transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301;lipid kinase activity#GO:0001727 lipid metabolic process#GO:0006629;signal transduction#GO:0007165;phospholipid biosynthetic process#GO:0008654;organophosphate biosynthetic process#GO:0090407;phosphatidylinositol biosynthetic process#GO:0006661;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;lipid biosynthetic process#GO:0008610;phosphatidylinositol phosphate biosynthetic process#GO:0046854;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;glycerolipid metabolic process#GO:0046486;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;signaling#GO:0023052;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular response to stimulus#GO:0051716;glycerolipid biosynthetic process#GO:0045017;cellular metabolic process#GO:0044237;cell communication#GO:0007154;glycerophospholipid metabolic process#GO:0006650;phosphatidylinositol metabolic process#GO:0046488;cell motility#GO:0048870;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0043491;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;glycerophospholipid biosynthetic process#GO:0046474;biological regulation#GO:0065007;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;cell migration#GO:0016477 cytoplasm#GO:0005737;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;phosphatidylinositol 3-kinase complex#GO:0005942;catalytic complex#GO:1902494;transferase complex#GO:1990234;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695;extrinsic component of membrane#GO:0019898 kinase#PC00137 PDGF signaling pathway#P00047>PI3K#P01168;Apoptosis signaling pathway#P00006>PI3K#P00310;Axon guidance mediated by netrin#P00009>PI3K#P00363;Hypoxia response via HIF activation#P00030>PI3K#P00823;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PI3K#P00868;Angiogenesis#P00005>PI3K#P00236;EGF receptor signaling pathway#P00018>PI3K#P00557;VEGF signaling pathway#P00056>PI3K#P01413;FGF signaling pathway#P00021>PI3K#P00640;Ras Pathway#P04393>PI3K#P04567;p53 pathway feedback loops 2#P04398>PI3K#P04661;p53 pathway#P00059>PI3K#P04609;Endothelin signaling pathway#P00019>PI3K#P00577;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>PI3K#P00900;Integrin signalling pathway#P00034>PI3K#P00936 CIOIN|Ensembl=ENSCING00000023373.1|UniProtKB=H2XTR6 H2XTR6 LOC101242258 PTHR31885:SF6 GH04784P GH04784P hydrolase activity#GO:0016787;catalytic activity#GO:0003824 cellular anatomical entity#GO:0110165;membrane#GO:0016020 CIOIN|Ensembl=ENSCING00000007652.3|UniProtKB=F6VWX3 F6VWX3 PTHR14002:SF20 ENDOGLIN/TGF-BETA RECEPTOR TYPE III ZONA PELLUCIDA-LIKE DOMAIN-CONTAINING PROTEIN 1 transmembrane signal receptor#PC00197 CIOIN|Ensembl=ENSCING00000013442.2|UniProtKB=F6V2S0 F6V2S0 PTHR47385:SF18 CALPONIN CALPONIN cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000016317.2|UniProtKB=F6W3V6 F6W3V6 PTHR15481:SF0 RIBONUCLEIC ACID BINDING PROTEIN S1 LD23870P-RELATED cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA splicing factor#PC00148;RNA processing factor#PC00147;RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000000181.3|UniProtKB=F7AB53 F7AB53 PTHR12040:SF0 ANTI-SILENCING PROTEIN 1 HISTONE CHAPERONE ASF1 protein binding#GO:0005515;binding#GO:0005488;histone binding#GO:0042393 cellular component organization or biogenesis#GO:0071840;chromatin organization#GO:0006325;protein-DNA complex organization#GO:0071824;cellular component organization#GO:0016043;cellular process#GO:0009987;protein-containing complex organization#GO:0043933 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-DNA complex#GO:0032993;chromosome#GO:0005694;chromatin#GO:0000785;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 CIOIN|Ensembl=ENSCING00000007441.3|UniProtKB=F7ANZ8 F7ANZ8 PTHR46340:SF1 UBX DOMAIN-CONTAINING PROTEIN 1 UBX DOMAIN-CONTAINING PROTEIN 1 protein binding#GO:0005515;binding#GO:0005488;polyubiquitin modification-dependent protein binding#GO:0031593;modification-dependent protein binding#GO:0140030 negative regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032435;regulation of proteolysis#GO:0030162;negative regulation of biological process#GO:0048519;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of catabolic process#GO:0009894;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of protein catabolic process#GO:0042177;negative regulation of metabolic process#GO:0009892;regulation of protein catabolic process#GO:0042176;negative regulation of protein metabolic process#GO:0051248;negative regulation of proteolysis#GO:0045861;regulation of proteolysis involved in protein catabolic process#GO:1903050;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of proteasomal protein catabolic process#GO:0061136;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;negative regulation of proteasomal protein catabolic process#GO:1901799;negative regulation of protein modification process#GO:0031400;negative regulation of catabolic process#GO:0009895;regulation of macromolecule metabolic process#GO:0060255;negative regulation of protein ubiquitination#GO:0031397;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of proteolysis involved in protein catabolic process#GO:1903051;regulation of metabolic process#GO:0019222;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000009038.3|UniProtKB=F6VI40 F6VI40 PTHR11037:SF21 TRANSCRIPTION FACTOR CP2 GEMINI, ISOFORM C DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218 CIOIN|Ensembl=ENSCING00000005343.3|UniProtKB=F7ALM5 F7ALM5 PTHR24216:SF8 PAXILLIN-RELATED PAXILLIN, ISOFORM F cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 Angiogenesis#P00005>Paxillin#P00194;VEGF signaling pathway#P00056>Paxillin#P01418;Integrin signalling pathway#P00034>Paxillin#P00950 CIOIN|Ensembl=ENSCING00000005776.3|UniProtKB=F6VUM2 F6VUM2 PTHR20852:SF57 GLUTAMINE SYNTHETASE GLUTAMINE SYNTHETASE 2 CYTOPLASMIC ligase activity#GO:0016874;catalytic activity#GO:0003824 organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;proteinogenic amino acid metabolic process#GO:0170039;proteinogenic amino acid biosynthetic process#GO:0170038;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;alpha-amino acid biosynthetic process#GO:1901607;nitrogen compound metabolic process#GO:0006807;amino acid biosynthetic process#GO:0008652;alpha-amino acid metabolic process#GO:1901605;small molecule biosynthetic process#GO:0044283;L-amino acid biosynthetic process#GO:0170034;carboxylic acid metabolic process#GO:0019752;L-amino acid metabolic process#GO:0170033;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ligase#PC00142;metabolite interconversion enzyme#PC00262 Glutamine glutamate conversion#P02745>Glutamine synthase#P04483;Glutamine glutamate conversion#P02745>Glutamine synthetase#P02968 CIOIN|Ensembl=ENSCING00000022892.1|UniProtKB=F6ZH30 F6ZH30 PTHR32343:SF22 SERINE/ARGININE-RICH SPLICING FACTOR LD29830P RNA splicing factor#PC00148;RNA metabolism protein#PC00031;RNA processing factor#PC00147 CIOIN|Ensembl=ENSCING00000001915.3|UniProtKB=F7A1W8 F7A1W8 PTHR22811:SF210 TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN RE49489P endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;Golgi organization#GO:0007030;macromolecule localization#GO:0033036;transport#GO:0006810;endomembrane system organization#GO:0010256;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;organelle organization#GO:0006996;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 COPII-coated ER to Golgi transport vesicle#GO:0030134;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;cellular anatomical entity#GO:0110165;organelle#GO:0043226;coated vesicle#GO:0030135;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;endoplasmic reticulum#GO:0005783;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793 vesicle coat protein#PC00235 CIOIN|Ensembl=ENSCING00000002753.3|UniProtKB=F7AHT0 F7AHT0 PTHR11426:SF280 HISTONE H3 HISTONE H3.3 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 DNA replication#P00017>Histones#P00527 CIOIN|Ensembl=ENSCING00000021004.1|UniProtKB=H2XWU7 H2XWU7 LOC100180720 PTHR21231:SF7 XPA-BINDING PROTEIN 1-RELATED GPN-LOOP GTPASE 3 hydrolase activity#GO:0016787;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824 small GTPase#PC00208;G-protein#PC00020;protein-binding activity modulator#PC00095 CIOIN|Ensembl=ENSCING00000016487.2|UniProtKB=F6YN79 F6YN79 PTHR10811:SF5 FRINGE-RELATED FRINGE GLYCOSYLTRANSFERASE acetylglucosaminyltransferase activity#GO:0008375;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194;hexosyltransferase activity#GO:0016758 glycosyltransferase#PC00111;metabolite interconversion enzyme#PC00262 Notch signaling pathway#P00045>Fringe#P01107 CIOIN|Ensembl=ENSCING00000018958.1|UniProtKB=H2Y2F6 H2Y2F6 LOC100183914 PTHR11711:SF30 ADP RIBOSYLATION FACTOR-RELATED ADP-RIBOSYLATION FACTOR 1 carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;anion binding#GO:0043168 cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 G-protein#PC00020 Integrin signalling pathway#P00034>Arf1#P00923;Huntington disease#P00029>ARF#P00786 CIOIN|Ensembl=ENSCING00000021457.1|UniProtKB=H2Y2U4 H2Y2U4 PTHR31816:SF3 MICOS COMPLEX SUBUNIT MIC13 MICOS COMPLEX SUBUNIT MIC13 cellular component organization or biogenesis#GO:0071840;membrane organization#GO:0061024;organelle organization#GO:0006996;cellular component organization#GO:0016043;mitochondrial membrane organization#GO:0007006;mitochondrion organization#GO:0007005;cellular process#GO:0009987;inner mitochondrial membrane organization#GO:0007007 envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle membrane contact site#GO:0044232;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial envelope#GO:0005740;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227;mitochondrial protein-containing complex#GO:0098798 CIOIN|Ensembl=ENSCING00000004602.3|UniProtKB=F6W3J5 F6W3J5 PTHR16146:SF46 INTELECTIN INTELECTIN-1A-RELATED CIOIN|Ensembl=ENSCING00000013443.1|UniProtKB=F6V2R4 F6V2R4 PTHR14308:SF0 WAP FOUR-DISULFIDE CORE DOMAIN PROTEIN 1 WAP FOUR-DISULFIDE CORE DOMAIN PROTEIN 1 biological regulation#GO:0065007;regulation of biological process#GO:0050789;regulation of cellular component organization#GO:0051128;regulation of growth#GO:0040008;regulation of cellular process#GO:0050794;regulation of cell growth#GO:0001558 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 CIOIN|Ensembl=ENSCING00000007569.3|UniProtKB=F7AMI3 F7AMI3 PTHR13869:SF24 MYELIN P0 RELATED BASEMENT MEMBRANE-SPECIFIC HEPARAN SULFATE PROTEOGLYCAN CORE PROTEIN-LIKE myelin protein#PC00161;structural protein#PC00211 CIOIN|Ensembl=ENSCING00000025097.1|UniProtKB=H2XSK5 H2XSK5 PTHR11878:SF70 SODIUM/CALCIUM EXCHANGER CALX-BETA DOMAIN-CONTAINING PROTEIN calcium ion transmembrane transporter activity#GO:0015085;secondary active transmembrane transporter activity#GO:0015291;inorganic molecular entity transmembrane transporter activity#GO:0015318;antiporter activity#GO:0015297;transmembrane transporter activity#GO:0022857;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;active monoatomic ion transmembrane transporter activity#GO:0022853;monoatomic cation transmembrane transporter activity#GO:0008324;monoatomic ion transmembrane transporter activity#GO:0015075;inorganic cation transmembrane transporter activity#GO:0022890;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;calcium ion transmembrane transport#GO:0070588;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;calcium ion transport#GO:0006816;localization#GO:0051179;calcium ion import#GO:0070509;import across plasma membrane#GO:0098739;sodium ion transport#GO:0006814;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;calcium ion transmembrane import into cytosol#GO:0097553;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;import into cell#GO:0098657;sodium ion transmembrane transport#GO:0035725 synapse#GO:0045202;neuron projection#GO:0043005;cell junction#GO:0030054;postsynapse#GO:0098794;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;sarcolemma#GO:0042383;axon#GO:0030424;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000022342.1|UniProtKB=H2XWR7 H2XWR7 LOC100185024 PTHR13364:SF6 DEFECTIVE SPERMATOGENESIS PROTEIN 39 SPERMATOGENESIS-DEFECTIVE PROTEIN 39 HOMOLOG cellular localization#GO:0051641;macromolecule localization#GO:0033036;vacuolar transport#GO:0007034;transport#GO:0006810;nitrogen compound transport#GO:0071705;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000015540.1|UniProtKB=F6SLJ7 F6SLJ7 PTHR22055:SF0 28 KDA HEAT- AND ACID-STABLE PHOSPHOPROTEIN PDGF-ASSOCIATED PROTEIN 28 KDA HEAT- AND ACID-STABLE PHOSPHOPROTEIN nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000018617.1|UniProtKB=H2Y2A9 H2Y2A9 PTHR22811:SF184 TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN 10 vesicle coat protein#PC00235 CIOIN|Ensembl=ENSCING00000014162.2|UniProtKB=F7A8D3 F7A8D3 PTHR13132:SF29 ALPHA- 1,6 -FUCOSYLTRANSFERASE ALPHA-(1,6)-FUCOSYLTRANSFERASE transferase activity#GO:0016740;fucosyltransferase activity#GO:0008417;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein glycosylation#GO:0006486;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein N-linked glycosylation#GO:0006487;protein metabolic process#GO:0019538;glycosylation#GO:0070085;glycoprotein metabolic process#GO:0009100;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 glycosyltransferase#PC00111 Notch signaling pathway#P00045>Neurotic#P01115 CIOIN|Ensembl=ENSCING00000021037.1|UniProtKB=H2XWM4 H2XWM4 LOC100177116 PTHR19282:SF477 TETRASPANIN TETRASPANIN cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000008562.3|UniProtKB=F6X1A2 F6X1A2 PTHR11848:SF226 TGF-BETA FAMILY LEFT-RIGHT DETERMINATION FACTOR molecular function activator activity#GO:0140677;binding#GO:0005488;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;protein binding#GO:0005515;cytokine activity#GO:0005125;signaling receptor binding#GO:0005102 anterior/posterior pattern specification#GO:0009952;multicellular organismal process#GO:0032501;pattern specification process#GO:0007389;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;regionalization#GO:0003002;developmental process#GO:0032502 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 growth factor#PC00112 Proline biosynthesis#P02768>Pyrroline-5-carboxylate reductase#P03113;TGF-beta signaling pathway#P00052>TGFbeta#P01286 CIOIN|Ensembl=ENSCING00000012622.1|UniProtKB=L7N0Q9 L7N0Q9 LOC778625 PTHR10811:SF5 FRINGE-RELATED FRINGE GLYCOSYLTRANSFERASE acetylglucosaminyltransferase activity#GO:0008375;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194;hexosyltransferase activity#GO:0016758 glycosyltransferase#PC00111;metabolite interconversion enzyme#PC00262 Notch signaling pathway#P00045>Fringe#P01107 CIOIN|Ensembl=ENSCING00000023135.1|UniProtKB=H2XX20 H2XX20 PTHR15907:SF204 DUF614 FAMILY PROTEIN-RELATED SUBFAMILY NOT NAMED CIOIN|Ensembl=ENSCING00000011850.2|UniProtKB=F6Z326 F6Z326 PTHR10088:SF4 GLUCOKINASE REGULATORY PROTEIN GLUCOKINASE REGULATORY PROTEIN protein-binding activity modulator#PC00095 CIOIN|Ensembl=ENSCING00000017922.1|UniProtKB=H2Y1Y7 H2Y1Y7 PTHR24160:SF1 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 53 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 53 regulation of microtubule-based process#GO:0032886;cellular localization#GO:0051641;organelle localization#GO:0051640;positive regulation of organelle organization#GO:0010638;nuclear division#GO:0000280;cell cycle process#GO:0022402;regulation of cellular component organization#GO:0051128;regulation of cell division#GO:0051302;mitotic cell cycle process#GO:1903047;chromosome segregation#GO:0007059;regulation of mitotic spindle organization#GO:0060236;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;mitotic cell cycle#GO:0000278;regulation of protein-containing complex assembly#GO:0043254;establishment of localization#GO:0051234;regulation of cellular component biogenesis#GO:0044087;regulation of microtubule cytoskeleton organization#GO:0070507;mitotic nuclear division#GO:0140014;mitotic sister chromatid segregation#GO:0000070;positive regulation of cellular component biogenesis#GO:0044089;regulation of protein polymerization#GO:0032271;positive regulation of biological process#GO:0048518;establishment of organelle localization#GO:0051656;regulation of cytokinesis#GO:0032465;nuclear chromosome segregation#GO:0098813;sister chromatid segregation#GO:0000819;establishment of chromosome localization#GO:0051303;regulation of organelle organization#GO:0033043;cellular component organization#GO:0016043;regulation of microtubule polymerization or depolymerization#GO:0031110;cellular process#GO:0009987;positive regulation of protein polymerization#GO:0032273;regulation of cell cycle process#GO:0010564;positive regulation of cellular process#GO:0048522;regulation of supramolecular fiber organization#GO:1902903;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;mitotic metaphase chromosome alignment#GO:0007080;organelle organization#GO:0006996;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;cell cycle#GO:0007049;organelle fission#GO:0048285;establishment of localization in cell#GO:0051649;regulation of cell cycle#GO:0051726;chromosome localization#GO:0050000;metaphase chromosome alignment#GO:0051310 intracellular non-membrane-bounded organelle#GO:0043232;spindle pole#GO:0000922;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;spindle#GO:0005819;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000011527.1|UniProtKB=F6W819 F6W819 PTHR11214:SF283 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE N-ACETYLLACTOSAMINIDE BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE 4-LIKE transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;protein O-linked glycosylation#GO:0006493;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 bounding membrane of organelle#GO:0098588;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;Golgi membrane#GO:0000139;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111 CIOIN|Ensembl=ENSCING00000008631.3|UniProtKB=F7AHM9 F7AHM9 PTHR10283:SF135 SOLUTE CARRIER FAMILY 13 MEMBER SOLUTE CARRIER FAMILY 13 MEMBER 5 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 localization#GO:0051179;establishment of localization#GO:0051234;cellular process#GO:0009987;transmembrane transport#GO:0055085;transport#GO:0006810 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000009042.3|UniProtKB=F6R6X6 F6R6X6 vglut PTHR11662:SF456 SOLUTE CARRIER FAMILY 17 VESICULAR GLUTAMATE TRANSPORTER, ISOFORM A secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000001989.3|UniProtKB=F6XG08 F6XG08 gad PTHR45677:SF10 GLUTAMATE DECARBOXYLASE-RELATED GLUTAMATE DECARBOXYLASE lyase activity#GO:0016829;carboxy-lyase activity#GO:0016831;carbon-carbon lyase activity#GO:0016830;catalytic activity#GO:0003824 organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;amino acid biosynthetic process#GO:0008652;small molecule biosynthetic process#GO:0044283;carboxylic acid metabolic process#GO:0019752;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 decarboxylase#PC00089 Gamma-aminobutyric acid synthesis#P04384>Glutamate decarboxylase#P04482 CIOIN|Ensembl=ENSCING00000002021.3|UniProtKB=F6W6J2 F6W6J2 PTHR13140:SF802 MYOSIN UNCONVENTIONAL MYOSIN-IB ISOFORM X1 microfilament motor activity#GO:0000146;cytoskeletal protein binding#GO:0008092;ATP-dependent activity#GO:0140657;binding#GO:0005488;actin filament binding#GO:0051015;cytoskeletal motor activity#GO:0003774;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779 actin filament-based movement#GO:0030048;transport#GO:0006810;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;establishment of localization#GO:0051234;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;import into cell#GO:0098657 microvillus#GO:0005902;actin-based cell projection#GO:0098858;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cytoskeleton#GO:0005856;cell projection#GO:0042995;plasma membrane#GO:0005886 actin binding motor protein#PC00040 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 CIOIN|Ensembl=ENSCING00000013335.2|UniProtKB=A0A1W2WN02 A0A1W2WN02 LOC100183957 PTHR10438:SF463 THIOREDOXIN THIOREDOXIN oxidoreductase#PC00176 Oxidative stress response#P00046>TRX#P01122;Hypoxia response via HIF activation#P00030>Thioredoxin#P00825 CIOIN|Ensembl=ENSCING00000002610.3|UniProtKB=F7B330 F7B330 PTHR16254:SF14 POTASSIUM/PROTON ANTIPORTER-RELATED TRANSMEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 3 CIOIN|Ensembl=ENSCING00000012255.2|UniProtKB=F7ALW9 F7ALW9 LOC100184915 PTHR12243:SF69 MADF DOMAIN TRANSCRIPTION FACTOR SI:CH73-59F11.3 regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218 CIOIN|Ensembl=ENSCING00000005286.3|UniProtKB=F6TV99 F6TV99 PTHR10201:SF331 MATRIX METALLOPROTEINASE MATRIX METALLOPROTEINASE-14-LIKE ISOFORM X1 hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular component organization or biogenesis#GO:0071840;extracellular structure organization#GO:0043062;external encapsulating structure organization#GO:0045229;catabolic process#GO:0009056;cellular component organization#GO:0016043;cellular process#GO:0009987;extracellular matrix organization#GO:0030198;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000003664.3|UniProtKB=F6YHI5 F6YHI5 LOC100178779 PTHR45964:SF9 WSCD FAMILY MEMBER CG9164 SULFOTRANSFERASE CIOIN|Ensembl=ENSCING00000020114.1|UniProtKB=Q869J2 Q869J2 Ci-GnRHR1 PTHR24241:SF59 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR ADIPOKINETIC HORMONE RECEPTOR, ISOFORM C signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;binding#GO:0005488;peptide binding#GO:0042277;transmembrane signaling receptor activity#GO:0004888;amide binding#GO:0033218 response to organic substance#GO:0010033;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to endogenous stimulus#GO:0009719;cellular response to hormone stimulus#GO:0032870;response to hormone#GO:0009725;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GsPCR#P00720;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GqPCR#P00730 CIOIN|Ensembl=ENSCING00000022697.1|UniProtKB=A0A1W2W835 A0A1W2W835 LOC494394 PTHR45679:SF5 ER DEGRADATION-ENHANCING ALPHA-MANNOSIDASE-LIKE PROTEIN 2 ER DEGRADATION-ENHANCING ALPHA-MANNOSIDASE-LIKE PROTEIN 1 CIOIN|Ensembl=ENSCING00000012002.2|UniProtKB=F6RWM4 F6RWM4 PTHR12483:SF115 SOLUTE CARRIER FAMILY 31 COPPER TRANSPORTERS COPPER TRANSPORT PROTEIN secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000007741.3|UniProtKB=F6Z9G9 F6Z9G9 LOC100184148 PTHR46314:SF2 SOLUTE CARRIER FAMILY 25 MEMBER 44 SOLUTE CARRIER FAMILY 25 MEMBER 44 transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;branched-chain amino acid transmembrane transporter activity#GO:0015658;amino acid transmembrane transporter activity#GO:0015171;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215;organic acid transmembrane transporter activity#GO:0005342 localization#GO:0051179;organic substance transport#GO:0071702;establishment of localization#GO:0051234;amino acid transport#GO:0006865;organic anion transport#GO:0015711;organic acid transport#GO:0015849;transport#GO:0006810;branched-chain amino acid transport#GO:0015803;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000006759.3|UniProtKB=F6SLC8 F6SLC8 LOC100181545 PTHR23305:SF11 OBG GTPASE FAMILY OBG-LIKE ATPASE 1 pyrophosphatase activity#GO:0016462;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;ATP hydrolysis activity#GO:0016887 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 G-protein#PC00020;protein-binding activity modulator#PC00095 CIOIN|Ensembl=ENSCING00000013951.2|UniProtKB=F6RQ51 F6RQ51 PTHR24248:SF174 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR TYRAMINE_OCTOPAMINE RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 CIOIN|Ensembl=ENSCING00000005459.3|UniProtKB=F6UTS4 F6UTS4 LOC100177909 PTHR14021:SF15 IRON-SULFUR CLUSTER CO-CHAPERONE PROTEIN HSCB IRON-SULFUR CLUSTER CO-CHAPERONE PROTEIN HSCB chaperone#PC00072 CIOIN|Ensembl=ENSCING00000003583.3|UniProtKB=F6XK22 F6XK22 LOC100183132 PTHR10412:SF11 MANNOSYL-OLIGOSACCHARIDE GLUCOSIDASE MANNOSYL-OLIGOSACCHARIDE GLUCOSIDASE hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;glucosidase activity#GO:0015926;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein N-linked glycosylation#GO:0006487;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 glucosidase#PC00108;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000019438.1|UniProtKB=H2XU46 H2XU46 PTHR43836:SF2 CATECHOL O-METHYLTRANSFERASE 1-RELATED CATECHOL O-METHYLTRANSFERASE 1-RELATED methyltransferase activity#GO:0008168;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;O-methyltransferase activity#GO:0008171;catalytic activity#GO:0003824 methyltransferase#PC00155;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000003504.3|UniProtKB=F6TLK5 F6TLK5 LOC100178661 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE SSU-1 sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824 cellular metabolic process#GO:0044237;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000003246.3|UniProtKB=F6Z5N9 F6Z5N9 PTHR43066:SF1 RHOMBOID-RELATED PROTEIN RHOMBOID PROTEIN 2 hydrolase activity#GO:0016787;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171 serine protease#PC00203;protease#PC00190 CIOIN|Ensembl=ENSCING00000009666.3|UniProtKB=F6W8G0 F6W8G0 PTHR43979:SF1 PRE-MRNA-PROCESSING FACTOR 17 PRE-MRNA-PROCESSING FACTOR 17 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704 ribonucleoprotein complex#GO:1990904;catalytic step 2 spliceosome#GO:0071013;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA splicing factor#PC00148;RNA processing factor#PC00147;RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000005917.3|UniProtKB=F6ZI02 F6ZI02 LOC100186223 PTHR10909:SF344 ELECTRON TRANSPORT OXIDOREDUCTASE PEROXISOMAL ACYL-COENZYME A OXIDASE 2 nucleotide binding#GO:0000166;fatty acid binding#GO:0005504;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;organic cyclic compound binding#GO:0097159;carboxylic acid binding#GO:0031406;nucleoside phosphate binding#GO:1901265;flavin adenine dinucleotide binding#GO:0050660;heterocyclic compound binding#GO:1901363;lipid binding#GO:0008289;anion binding#GO:0043168;ion binding#GO:0043167;organic acid binding#GO:0043177 oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;lipid oxidation#GO:0034440;cellular metabolic process#GO:0044237;homeostatic process#GO:0042592;lipid catabolic process#GO:0016042;lipid modification#GO:0030258;chemical homeostasis#GO:0048878;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;fatty acid catabolic process#GO:0009062;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;fatty acid metabolic process#GO:0006631;small molecule catabolic process#GO:0044282;fatty acid beta-oxidation#GO:0006635;lipid homeostasis#GO:0055088;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;cellular lipid metabolic process#GO:0044255;cellular lipid catabolic process#GO:0044242;carboxylic acid metabolic process#GO:0019752;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;monocarboxylic acid catabolic process#GO:0072329 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;microbody#GO:0042579;membrane-bounded organelle#GO:0043227;peroxisome#GO:0005777;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000004160.3|UniProtKB=F7A669 F7A669 PTHR47977:SF12 RAS-RELATED PROTEIN RAB RAS-RELATED PROTEIN RAB-44 GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;ion binding#GO:0043167;anion binding#GO:0043168 localization#GO:0051179;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization#GO:0051234;transport#GO:0006810 small GTPase#PC00208;G-protein#PC00020 CIOIN|Ensembl=ENSCING00000008365.4|UniProtKB=F7A1T4 F7A1T4 PTHR12726:SF0 CERAMIDE GLUCOSYLTRANSFERASE CERAMIDE GLUCOSYLTRANSFERASE UDP-glucosyltransferase activity#GO:0035251;glucosyltransferase activity#GO:0046527;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;UDP-glycosyltransferase activity#GO:0008194 lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;glycosphingolipid biosynthetic process#GO:0006688;glycolipid metabolic process#GO:0006664;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;liposaccharide metabolic process#GO:1903509;membrane lipid biosynthetic process#GO:0046467;sphingolipid metabolic process#GO:0006665;primary metabolic process#GO:0044238;ceramide metabolic process#GO:0006672;amide biosynthetic process#GO:0043604;carbohydrate derivative biosynthetic process#GO:1901137;membrane lipid metabolic process#GO:0006643;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;ceramide biosynthetic process#GO:0046513;glycolipid biosynthetic process#GO:0009247;cellular lipid metabolic process#GO:0044255;amide metabolic process#GO:0043603;sphingolipid biosynthetic process#GO:0030148;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;membrane#GO:0016020 glycosyltransferase#PC00111 CIOIN|Ensembl=ENSCING00000014399.2|UniProtKB=F6ZX85 F6ZX85 PTHR22588:SF3 VWFA DOMAIN-CONTAINING PROTEIN VWFA DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000023259.1|UniProtKB=H2XN55 H2XN55 LOC100180005 PTHR45742:SF8 COMPLEMENT COMPONENT C6 FLOCCULATION PROTEIN FLO11 complement component#PC00078 CIOIN|Ensembl=ENSCING00000021472.1|UniProtKB=H2XQE2 H2XQE2 PTHR23024:SF24 ARYLACETAMIDE DEACETYLASE ALPHA_BETA HYDROLASE FOLD-3 DOMAIN-CONTAINING PROTEIN deacetylase#PC00087;metabolite interconversion enzyme#PC00262;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000014743.2|UniProtKB=C4B8X6 C4B8X6 Ci-RSP9 PTHR22069:SF0 MITOCHONDRIAL RIBOSOMAL PROTEIN S18 RADIAL SPOKE HEAD PROTEIN 9 HOMOLOG cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cell projection organization#GO:0030030;microtubule cytoskeleton organization#GO:0000226;microtubule-based movement#GO:0007018;cilium or flagellum-dependent cell motility#GO:0001539;cell motility#GO:0048870;cellular component organization#GO:0016043;axoneme assembly#GO:0035082;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031;cilium movement involved in cell motility#GO:0060294;cilium movement#GO:0003341;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cilium-dependent cell motility#GO:0060285;microtubule-based process#GO:0007017;organelle organization#GO:0006996;microtubule bundle formation#GO:0001578;cytoskeleton organization#GO:0007010;plasma membrane bounded cell projection assembly#GO:0120031;motile cilium assembly#GO:0044458 axoneme#GO:0005930;cytoplasmic region#GO:0099568;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;plasma membrane bounded cell projection cytoplasm#GO:0032838;membrane-bounded organelle#GO:0043227;ciliary plasm#GO:0097014;cytoskeleton#GO:0005856;cell projection#GO:0042995;cilium#GO:0005929 ribosomal protein#PC00202;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000007160.3|UniProtKB=F7BGD6 F7BGD6 PTHR34487:SF1 ACYL-ACP THIOESTERASE ACYL-ACP THIOESTERASE CIOIN|Ensembl=ENSCING00000003625.3|UniProtKB=F6U8A8 F6U8A8 PTHR20886:SF11 VANG-LIKE PROTEIN VANG-LIKE PROTEIN signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;epithelium development#GO:0060429;non-canonical Wnt signaling pathway#GO:0035567;developmental process#GO:0032502;cell communication#GO:0007154;cellular process#GO:0009987;cell-cell signaling by wnt#GO:0198738;tissue development#GO:0009888;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;anatomical structure morphogenesis#GO:0009653;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;tissue morphogenesis#GO:0048729;morphogenesis of an epithelium#GO:0002009;cell-cell signaling#GO:0007267;signaling#GO:0023052;Wnt signaling pathway#GO:0016055 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 CIOIN|Ensembl=ENSCING00000012704.2|UniProtKB=F6TEV5 F6TEV5 PTHR12918:SF1 CYSTEINE DIOXYGENASE CYSTEINE DIOXYGENASE TYPE 1 cation binding#GO:0043169;oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702;ferrous iron binding#GO:0008198;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;iron ion binding#GO:0005506;dioxygenase activity#GO:0051213;transition metal ion binding#GO:0046914;metal ion binding#GO:0046872;ion binding#GO:0043167;oxidoreductase activity#GO:0016491 oxygenase#PC00177;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000025060.1|UniProtKB=H2XKE7 H2XKE7 PTHR17408:SF0 HISTONE RNA HAIRPIN-BINDING PROTEIN HISTONE RNA HAIRPIN-BINDING PROTEIN nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;pre-mRNA binding#GO:0036002;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;macromolecule localization#GO:0033036;RNA metabolic process#GO:0016070;transport#GO:0006810;RNA processing#GO:0006396;nucleic acid transport#GO:0050657;nitrogen compound transport#GO:0071705;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA localization#GO:0006403;mRNA 3'-end processing#GO:0031124;organic substance transport#GO:0071702;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;RNA transport#GO:0050658;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;establishment of RNA localization#GO:0051236;RNA 3'-end processing#GO:0031123;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;mRNA transport#GO:0051028;cellular process#GO:0009987;primary metabolic process#GO:0044238;localization#GO:0051179;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound transport#GO:0015931;mRNA processing#GO:0006397 cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000000657.3|UniProtKB=Q4H398 Q4H398 Ci-LAG1-like 4 PTHR12560:SF0 LONGEVITY ASSURANCE FACTOR 1 LAG1 LD18904P transferase activity#GO:0016740;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity#GO:0003824;N-acyltransferase activity#GO:0016410 lipid metabolic process#GO:0006629;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;membrane lipid biosynthetic process#GO:0046467;sphingolipid metabolic process#GO:0006665;ceramide metabolic process#GO:0006672;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;membrane lipid metabolic process#GO:0006643;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;ceramide biosynthetic process#GO:0046513;cellular lipid metabolic process#GO:0044255;amide metabolic process#GO:0043603;sphingolipid biosynthetic process#GO:0030148;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000022406.1|UniProtKB=H2Y0L6 H2Y0L6 PTHR34762:SF1 SMALL VASOHIBIN-BINDING PROTEIN SMALL VASOHIBIN-BINDING PROTEIN cellular localization#GO:0051641;negative regulation of biological process#GO:0048519;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;macromolecule localization#GO:0033036;regulation of nitrogen compound metabolic process#GO:0051171;transport#GO:0006810;nitrogen compound transport#GO:0071705;protein secretion#GO:0009306;establishment of protein localization#GO:0045184;regulation of biological process#GO:0050789;negative regulation of protein modification process#GO:0031400;organic substance transport#GO:0071702;establishment of localization#GO:0051234;secretion#GO:0046903;secretion by cell#GO:0032940;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;cellular process#GO:0009987;negative regulation of nitrogen compound metabolic process#GO:0051172;protein localization#GO:0008104;regulation of primary metabolic process#GO:0080090;localization#GO:0051179;establishment of protein localization to extracellular region#GO:0035592;cellular macromolecule localization#GO:0070727;regulation of macromolecule metabolic process#GO:0060255;negative regulation of protein ubiquitination#GO:0031397;negative regulation of macromolecule metabolic process#GO:0010605;protein transport#GO:0015031;biological regulation#GO:0065007;protein localization to extracellular region#GO:0071692;export from cell#GO:0140352;regulation of metabolic process#GO:0019222 cellular anatomical entity#GO:0110165;apical part of cell#GO:0045177 CIOIN|Ensembl=ENSCING00000021691.1|UniProtKB=H2Y0B1 H2Y0B1 PTHR13093:SF0 ZINC FINGER HIT DOMAIN CONTAINING PROTEIN 1 ZGC:112524 nucleosome binding#GO:0031491;protein-containing complex binding#GO:0044877;binding#GO:0005488;chromatin binding#GO:0003682 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-DNA complex#GO:0032993;chromatin#GO:0000785;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;ATPase complex#GO:1904949;intracellular organelle lumen#GO:0070013;INO80-type complex#GO:0097346;cellular anatomical entity#GO:0110165;SWI/SNF superfamily-type complex#GO:0070603;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;histone deacetylase complex#GO:0000118;nuclear lumen#GO:0031981;Swr1 complex#GO:0000812;nuclear protein-containing complex#GO:0140513 chromatin/chromatin-binding, or -regulatory protein#PC00077 CIOIN|Ensembl=ENSCING00000021815.1|UniProtKB=H2XR71 H2XR71 PTHR11588:SF4 TUBULIN TUBULIN DELTA CHAIN carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;structural molecule activity#GO:0005198;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167;structural constituent of cytoskeleton#GO:0005200 cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;microtubule-based process#GO:0007017;organelle organization#GO:0006996;microtubule cytoskeleton organization#GO:0000226;cytoskeleton organization#GO:0007010;cell cycle#GO:0007049;cellular component organization#GO:0016043;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622 tubulin#PC00228;microtubule or microtubule-binding cytoskeletal protein#PC00157 CIOIN|Ensembl=ENSCING00000006762.3|UniProtKB=F6XBA5 F6XBA5 PTHR12086:SF9 EF-HAND DOMAIN C-TERMINAL CONTAINING PROTEIN EF-HAND DOMAIN-CONTAINING PROTEIN 1 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;tubulin binding#GO:0015631;alpha-tubulin binding#GO:0043014;binding#GO:0005488 cell division#GO:0051301;mitotic spindle organization#GO:0007052;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;cilium or flagellum-dependent cell motility#GO:0001539;cell motility#GO:0048870;cellular component organization#GO:0016043;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cellular process#GO:0009987;mitotic cell cycle process#GO:1903047;cellular component organization or biogenesis#GO:0071840;cilium-dependent cell motility#GO:0060285;mitotic cytokinesis#GO:0000281;mitotic cell cycle#GO:0000278;microtubule-based process#GO:0007017;organelle organization#GO:0006996;cytoskeleton-dependent cytokinesis#GO:0061640;cell cycle#GO:0007049;cytoskeleton organization#GO:0007010;spindle organization#GO:0007051;cytokinesis#GO:0000910 axoneme#GO:0005930;cytoplasmic region#GO:0099568;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;mitotic spindle#GO:0072686;microtubule cytoskeleton#GO:0015630;ciliary plasm#GO:0097014;plasma membrane bounded cell projection cytoplasm#GO:0032838;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;cell projection#GO:0042995;cilium#GO:0005929;spindle#GO:0005819 calmodulin-related#PC00061 CIOIN|Ensembl=ENSCING00000001421.3|UniProtKB=F6YRU6 F6YRU6 PTHR16206:SF19 DEP DOMAIN-CONTAINING DEP DOMAIN-CONTAINING PROTEIN scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000005035.3|UniProtKB=F6TA62 F6TA62 LOC100183866 PTHR23035:SF1 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 97-RELATED CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 97 CIOIN|Ensembl=ENSCING00000014857.2|UniProtKB=F7BG20 F7BG20 PTHR24229:SF112 NEUROPEPTIDES RECEPTOR CHEMOKINE-LIKE RECEPTOR 1 neuropeptide binding#GO:0042923;signaling receptor activity#GO:0038023;binding#GO:0005488;peptide binding#GO:0042277;amide binding#GO:0033218;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;neuropeptide signaling pathway#GO:0007218;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;neuron projection#GO:0043005;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 CIOIN|Ensembl=ENSCING00000004216.3|UniProtKB=F6YGU3 F6YGU3 LOC100181494 PTHR10044:SF139 INHIBITOR OF APOPTOSIS DEATH-ASSOCIATED INHIBITOR OF APOPTOSIS 2 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protease inhibitor#PC00191 CIOIN|Gene=FGFR|UniProtKB=Q4H3K6 Q4H3K6 FGFR PTHR24416:SF550 TYROSINE-PROTEIN KINASE RECEPTOR FIBROBLAST GROWTH FACTOR RECEPTOR HOMOLOG 1-RELATED signaling receptor activity#GO:0038023;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;molecular transducer activity#GO:0060089;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672;transmembrane signaling receptor activity#GO:0004888 signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;positive regulation of cellular metabolic process#GO:0031325;developmental process#GO:0032502;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;regulation of molecular function#GO:0065009;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;positive regulation of phosphorylation#GO:0042327;cellular response to stimulus#GO:0051716;positive regulation of catalytic activity#GO:0043085;multicellular organism development#GO:0007275;positive regulation of phosphorus metabolic process#GO:0010562;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphate metabolic process#GO:0045937;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;multicellular organismal process#GO:0032501;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 receptor complex#GO:0043235;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 CIOIN|Ensembl=ENSCING00000003046.3|UniProtKB=F6QST8 F6QST8 PTHR23003:SF3 RNA RECOGNITION MOTIF RRM DOMAIN CONTAINING PROTEIN FI21236P1-RELATED nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA splicing factor#PC00148;RNA processing factor#PC00147;RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000013139.2|UniProtKB=F6YZ22 F6YZ22 PTHR15952:SF11 EXPORTIN-T/LOS1 EXPORTIN-T tRNA binding#GO:0000049;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular localization#GO:0051641;macromolecule localization#GO:0033036;establishment of RNA localization#GO:0051236;transport#GO:0006810;nucleic acid transport#GO:0050657;nitrogen compound transport#GO:0071705;cellular process#GO:0009987;RNA localization#GO:0006403;localization#GO:0051179;organic substance transport#GO:0071702;nuclear export#GO:0051168;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;RNA transport#GO:0050658;nucleobase-containing compound transport#GO:0015931;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;nuclear transport#GO:0051169 envelope#GO:0031975;membrane-enclosed lumen#GO:0031974;nuclear pore#GO:0005643;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;nuclear periphery#GO:0034399;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000014977.2|UniProtKB=F6S2V0 F6S2V0 PTHR24096:SF149 LONG-CHAIN-FATTY-ACID--COA LIGASE AMP-BINDING DOMAIN-CONTAINING PROTEIN-RELATED ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877 metabolite interconversion enzyme#PC00262;ligase#PC00142 CIOIN|Ensembl=ENSCING00000025125.1|UniProtKB=H2XNX1 H2XNX1 PTHR45791:SF6 CALCIUM AND INTEGRIN BINDING FAMILY MEMBER 2 CALCIUM AND INTEGRIN BINDING FAMILY MEMBER 2 cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;magnesium ion binding#GO:0000287;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488 inorganic ion homeostasis#GO:0098771;monoatomic cation homeostasis#GO:0055080;homeostatic process#GO:0042592;calcium ion homeostasis#GO:0055074;chemical homeostasis#GO:0048878;monoatomic ion homeostasis#GO:0050801 CIOIN|Ensembl=ENSCING00000002318.3|UniProtKB=F6PNW9 F6PNW9 PTHR48083:SF13 MEDIUM-CHAIN SPECIFIC ACYL-COA DEHYDROGENASE, MITOCHONDRIAL-RELATED ACYL-COA DEHYDROGENASE FAMILY MEMBER 11 oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;lipid oxidation#GO:0034440;cellular metabolic process#GO:0044237;lipid catabolic process#GO:0016042;lipid modification#GO:0030258;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;fatty acid catabolic process#GO:0009062;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;fatty acid metabolic process#GO:0006631;small molecule catabolic process#GO:0044282;fatty acid beta-oxidation#GO:0006635;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;cellular lipid metabolic process#GO:0044255;cellular lipid catabolic process#GO:0044242;carboxylic acid metabolic process#GO:0019752;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;monocarboxylic acid catabolic process#GO:0072329 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 dehydrogenase#PC00092;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000006462.3|UniProtKB=F6V4B3 F6V4B3 PTHR23065:SF15 PROLINE-SERINE-THREONINE PHOSPHATASE INTERACTING PROTEIN 1 AT02057P cytoplasm#GO:0005737;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 CIOIN|Ensembl=ENSCING00000006569.3|UniProtKB=F6RIC2 F6RIC2 LOC100180654 PTHR15496:SF2 GENERAL TRANSCRIPTION FACTOR 3C POLYPEPTIDE 4 FAMILY GENERAL TRANSCRIPTION FACTOR 3C POLYPEPTIDE 4 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;transcription factor TFIIIC complex#GO:0000127 general transcription factor#PC00259 CIOIN|Ensembl=ENSCING00000008548.3|UniProtKB=H2XZT6 H2XZT6 PTHR22807:SF30 NOP2 YEAST -RELATED NOL1/NOP2/FMU SUN DOMAIN-CONTAINING 28S RRNA (CYTOSINE(4447)-C(5))-METHYLTRANSFERASE-RELATED cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;RNA modification#GO:0009451;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;methylation#GO:0032259;macromolecule methylation#GO:0043414;nitrogen compound metabolic process#GO:0006807;RNA methylation#GO:0001510;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 RNA methyltransferase#PC00033 CIOIN|Ensembl=ENSCING00000019548.1|UniProtKB=H2XPY5 H2XPY5 LOC100183589 PTHR11802:SF201 SERINE PROTEASE FAMILY S10 SERINE CARBOXYPEPTIDASE CARBOXYPEPTIDASE hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171;carboxypeptidase activity#GO:0004180 serine protease#PC00203;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000001159.3|UniProtKB=F6UKM1 F6UKM1 PTHR32026:SF10 METHYLTRANSFERASE-LIKE PROTEIN 24 METHYLTRANSFERASE-LIKE PROTEIN 24-RELATED methyltransferase#PC00155 CIOIN|Ensembl=ENSCING00000012924.2|UniProtKB=F6RM35 F6RM35 gpx7 PTHR11592:SF78 GLUTATHIONE PEROXIDASE GLUTATHIONE PEROXIDASE peroxidase#PC00180;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000003181.3|UniProtKB=F6QDE3 F6QDE3 PTHR12858:SF2 RIBOSOME BIOGENESIS PROTEIN RIBOSOME BIOGENESIS PROTEIN BMS1 HOMOLOG snoRNA binding#GO:0030515;GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;nucleic acid binding#GO:0003676;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;RNA binding#GO:0003723;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;anion binding#GO:0043168;ion binding#GO:0043167 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;RNA processing#GO:0006396;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;ribosome biogenesis#GO:0042254;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;maturation of SSU-rRNA#GO:0030490;ribosomal small subunit biogenesis#GO:0042274 ribonucleoprotein complex#GO:1990904;preribosome#GO:0030684;protein-containing complex#GO:0032991;90S preribosome#GO:0030686 CIOIN|Ensembl=ENSCING00000004501.3|UniProtKB=F7ATQ3 F7ATQ3 LOC100179814 PTHR15959:SF0 SYNTAXIN-18 SYNTAXIN-18 localization#GO:0051179;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization#GO:0051234;Golgi vesicle transport#GO:0048193;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;transport#GO:0006810 cytoplasm#GO:0005737;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;SNARE complex#GO:0031201;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 SNARE protein#PC00034;membrane traffic protein#PC00150 CIOIN|Ensembl=ENSCING00000018894.1|UniProtKB=H2XZ08 H2XZ08 LOC100181775 PTHR23115:SF301 TRANSLATION FACTOR ELONGATION FACTOR 1-ALPHA GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;nucleic acid binding#GO:0003676;translation regulator activity#GO:0045182;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;translation regulator activity, nucleic acid binding#GO:0090079;translation elongation factor activity#GO:0003746;translation factor activity, RNA binding#GO:0008135 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;translational elongation#GO:0006414;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 translation factor#PC00223;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000005914.3|UniProtKB=Q4H3E2 Q4H3E2 Ci-HTATSF1 PTHR15608:SF0 SPLICING FACTOR U2AF-ASSOCIATED PROTEIN 2 HIV TAT-SPECIFIC FACTOR 1 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;U2-type spliceosomal complex#GO:0005684;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;spliceosomal snRNP complex#GO:0097525;protein-containing complex#GO:0032991;small nuclear ribonucleoprotein complex#GO:0030532;U2 snRNP#GO:0005686;membrane-bounded organelle#GO:0043227;Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513 RNA splicing factor#PC00148;RNA processing factor#PC00147;RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000024611.1|UniProtKB=H2XN51 H2XN51 PTHR19964:SF92 MULTIPLE PDZ DOMAIN PROTEIN PATJ HOMOLOG scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000012967.2|UniProtKB=F6RBK2 F6RBK2 PTHR19855:SF11 WD40 REPEAT PROTEIN 12, 37 RIBOSOME BIOGENESIS PROTEIN WDR12 CIOIN|Ensembl=ENSCING00000003870.3|UniProtKB=F6XGS0 F6XGS0 PTHR10454:SF210 CASPASE CASPASE-2 protease#PC00190;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000001907.3|UniProtKB=F7A2C9 F7A2C9 PTHR22753:SF14 TRANSMEMBRANE PROTEIN 68 MONOACYLGLYCEROL_DIACYLGLYCEROL O-ACYLTRANSFERASE cellular anatomical entity#GO:0110165;membrane#GO:0016020 CIOIN|Ensembl=ENSCING00000024484.1|UniProtKB=H2XVL0 H2XVL0 PTHR43684:SF1 FAMILY NOT NAMED ENOYL-COA DELTA ISOMERASE 2 CIOIN|Ensembl=ENSCING00000000485.3|UniProtKB=F6YCJ4 F6YCJ4 LOC100180086 PTHR10264:SF127 BAND 7 PROTEIN-RELATED PODOCIN cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cytoskeletal protein#PC00085 CIOIN|Ensembl=ENSCING00000020442.1|UniProtKB=H2XMH4 H2XMH4 LOC100180708 PTHR23083:SF464 TETRATRICOPEPTIDE REPEAT PROTEIN, TPR TETRATRICOPEPTIDE REPEAT DOMAIN 7, ISOFORM A CIOIN|Ensembl=ENSCING00000021452.1|UniProtKB=H2Y1S7 H2Y1S7 PTHR45815:SF3 PROTEIN DISULFIDE-ISOMERASE A6 PROTEIN DISULFIDE-ISOMERASE A6 protein-disulfide reductase activity#GO:0015035;disulfide oxidoreductase activity#GO:0015036;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;response to stress#GO:0006950;response to endoplasmic reticulum stress#GO:0034976;cellular process#GO:0009987;cellular response to stress#GO:0033554 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;endoplasmic reticulum lumen#GO:0005788;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chaperone#PC00072 CIOIN|Ensembl=ENSCING00000002205.3|UniProtKB=F6ZQ14 F6ZQ14 PTHR13459:SF1 E3 UBIQUITIN-PROTEIN LIGASE RNF220 ISOFORM X1 E3 UBIQUITIN-PROTEIN LIGASE RNF220 ISOFORM X1 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 CIOIN|Ensembl=ENSCING00000008495.3|UniProtKB=F7B2N2 F7B2N2 rgc PTHR48027:SF4 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN 87F-RELATED MULTICOPY SUPPRESSOR OF SPORULATION PROTEIN MSA1 CIOIN|Ensembl=ENSCING00000007239.4|UniProtKB=F7AFD2 F7AFD2 PTHR13673:SF0 ESOPHAGEAL CANCER ASSOCIATED PROTEIN VPS35 ENDOSOMAL PROTEIN-SORTING FACTOR-LIKE localization#GO:0051179;endosomal transport#GO:0016197;localization within membrane#GO:0051668;cellular localization#GO:0051641;vesicle-mediated transport to the plasma membrane#GO:0098876;endocytic recycling#GO:0032456;establishment of localization#GO:0051234;transport#GO:0006810;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;cellular process#GO:0009987 cytoplasm#GO:0005737;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000002169.3|UniProtKB=F6SSQ7 F6SSQ7 PTHR15075:SF2 ALPHA-MANNOSIDE BETA-1,6-N-ACETYLGLUCOSAMINYLTRANSFERASE ALPHA-1,6-MANNOSYLGLYCOPROTEIN 6-BETA-N-ACETYLGLUCOSAMINYLTRANSFERASE acetylglucosaminyltransferase activity#GO:0008375;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;UDP-glycosyltransferase activity#GO:0008194 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein N-linked glycosylation#GO:0006487;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111 CIOIN|Ensembl=ENSCING00000023847.1|UniProtKB=H2XVC3 H2XVC3 PTHR21231:SF8 XPA-BINDING PROTEIN 1-RELATED GPN-LOOP GTPASE 1 hydrolase activity#GO:0016787;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824 small GTPase#PC00208;G-protein#PC00020;protein-binding activity modulator#PC00095 CIOIN|Ensembl=ENSCING00000002656.3|UniProtKB=F6YDH8 F6YDH8 PTHR23138:SF141 RAN BINDING PROTEIN NUCLEAR PORE COMPLEX PROTEIN NUP50 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000003517.3|UniProtKB=F7BHL8 F7BHL8 PTHR45672:SF3 PROTEIN DISULFIDE-ISOMERASE C17H9.14C-RELATED THIOREDOXIN DOMAIN-CONTAINING PROTEIN 5 isomerase activity#GO:0016853;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;protein disulfide isomerase activity#GO:0003756 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein folding#GO:0006457;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chaperone#PC00072 CIOIN|Ensembl=ENSCING00000006204.2|UniProtKB=F6ZEA6 F6ZEA6 PTHR24238:SF74 G-PROTEIN COUPLED RECEPTOR PROKINETICIN RECEPTOR 2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;neuropeptide receptor activity#GO:0008188;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;neuropeptide signaling pathway#GO:0007218;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 CIOIN|Ensembl=ENSCING00000021528.1|UniProtKB=A0A1W2WAU2 A0A1W2WAU2 LOC100178028 PTHR10258:SF12 CALCIUM-ACTIVATED POTASSIUM CHANNEL SUBUNIT BETA SUBFAMILY NOT NAMED monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;potassium ion transmembrane transporter activity#GO:0015079;molecular function regulator activity#GO:0098772;transporter regulator activity#GO:0141108;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;channel activity#GO:0015267;monoatomic ion-gated channel activity#GO:0022839;calcium-activated potassium channel activity#GO:0015269;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;calcium-activated cation channel activity#GO:0005227;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;potassium channel regulator activity#GO:0015459;ligand-gated monoatomic cation channel activity#GO:0099094;channel regulator activity#GO:0016247;monoatomic ion channel activity#GO:0005216;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion transmembrane transporter activity#GO:0015075;ligand-gated channel activity#GO:0022834 detection of stimulus#GO:0051606;response to stimulus#GO:0050896;response to chemical#GO:0042221;detection of chemical stimulus#GO:0009593 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;voltage-gated potassium channel complex#GO:0008076;cation channel complex#GO:0034703;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227;voltage-gated ion channel#PC00241 CIOIN|Ensembl=ENSCING00000012575.2|UniProtKB=F6YNK9 F6YNK9 PTHR13453:SF1 KAT8 REGULATORY NSL COMPLEX SUBUNIT 2 KAT8 REGULATORY NSL COMPLEX SUBUNIT 2 histone acetyltransferase complex#GO:0000123;acetyltransferase complex#GO:1902493;protein-DNA complex#GO:0032993;chromatin#GO:0000785;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein acetyltransferase complex#GO:0031248;protein-containing complex#GO:0032991;chromosome#GO:0005694 CIOIN|Ensembl=ENSCING00000007589.3|UniProtKB=A0A1W2WKR4 A0A1W2WKR4 LOC101242512 PTHR11588:SF504 TUBULIN TUBULIN BETA-1 CHAIN-RELATED carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;structural molecule activity#GO:0005198;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167;structural constituent of cytoskeleton#GO:0005200 cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;microtubule-based process#GO:0007017;organelle organization#GO:0006996;microtubule cytoskeleton organization#GO:0000226;cytoskeleton organization#GO:0007010;cell cycle#GO:0007049;cellular component organization#GO:0016043;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622 tubulin#PC00228;microtubule or microtubule-binding cytoskeletal protein#PC00157 Huntington disease#P00029>Microtubule#P00780;Huntington disease#P00029>beta-Tubulin#P00790;Cytoskeletal regulation by Rho GTPase#P00016>tubulin#P00526 CIOIN|Ensembl=ENSCING00000024849.1|UniProtKB=H2XY21 H2XY21 PTHR10909:SF344 ELECTRON TRANSPORT OXIDOREDUCTASE PEROXISOMAL ACYL-COENZYME A OXIDASE 2 nucleotide binding#GO:0000166;fatty acid binding#GO:0005504;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;organic cyclic compound binding#GO:0097159;carboxylic acid binding#GO:0031406;nucleoside phosphate binding#GO:1901265;flavin adenine dinucleotide binding#GO:0050660;heterocyclic compound binding#GO:1901363;lipid binding#GO:0008289;anion binding#GO:0043168;ion binding#GO:0043167;organic acid binding#GO:0043177 oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;lipid oxidation#GO:0034440;cellular metabolic process#GO:0044237;homeostatic process#GO:0042592;lipid catabolic process#GO:0016042;lipid modification#GO:0030258;chemical homeostasis#GO:0048878;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;fatty acid catabolic process#GO:0009062;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;fatty acid metabolic process#GO:0006631;small molecule catabolic process#GO:0044282;fatty acid beta-oxidation#GO:0006635;lipid homeostasis#GO:0055088;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;cellular lipid metabolic process#GO:0044255;cellular lipid catabolic process#GO:0044242;carboxylic acid metabolic process#GO:0019752;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;monocarboxylic acid catabolic process#GO:0072329 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;microbody#GO:0042579;membrane-bounded organelle#GO:0043227;peroxisome#GO:0005777;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000023883.1|UniProtKB=H2Y3U6 H2Y3U6 PTHR46454:SF18 DYNEIN AXONEMAL HEAVY CHAIN 7-RELATED DYNEIN HEAVY CHAIN REGION D6 P-LOOP DOMAIN-CONTAINING PROTEIN microtubule or microtubule-binding cytoskeletal protein#PC00157 CIOIN|Ensembl=ENSCING00000005744.3|UniProtKB=F6Q021 F6Q021 LOC100181113 PTHR23237:SF6 NUCLEOLAR PROTEIN FAMILY A MEMBER 1 SNORNP PROTEIN GAR1 H_ACA RIBONUCLEOPROTEIN COMPLEX SUBUNIT 1 snoRNA binding#GO:0030515;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;RNA modification#GO:0009451;rRNA modification#GO:0000154;RNA processing#GO:0006396;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;ribosome biogenesis#GO:0042254;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;pseudouridine synthesis#GO:0001522;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;sno(s)RNA-containing ribonucleoprotein complex#GO:0005732;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000024645.1|UniProtKB=H2XVE0 H2XVE0 LOC100184292 PTHR45909:SF1 ADP-RIBOSYLATION FACTOR-RELATED PROTEIN 1 ADP-RIBOSYLATION FACTOR-RELATED PROTEIN 1 GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;anion binding#GO:0043168;ion binding#GO:0043167 protein localization to plasma membrane#GO:0072659;localization within membrane#GO:0051668;cellular localization#GO:0051641;vesicle-mediated transport to the plasma membrane#GO:0098876;macromolecule localization#GO:0033036;protein localization to membrane#GO:0072657;post-Golgi vesicle-mediated transport#GO:0006892;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;protein localization to Golgi apparatus#GO:0034067;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;establishment of protein localization#GO:0045184;Golgi to plasma membrane transport#GO:0006893;protein localization#GO:0008104;localization#GO:0051179;protein localization to cell periphery#GO:1990778;organic substance transport#GO:0071702;establishment of protein localization to membrane#GO:0090150;Golgi to plasma membrane protein transport#GO:0043001;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;protein localization to organelle#GO:0033365 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000020713.1|UniProtKB=H2XLG8 H2XLG8 PTHR10127:SF780 DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING METALLOENDOPEPTIDASE hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000019603.1|UniProtKB=H2XSU5 H2XSU5 PTHR24412:SF497 KELCH PROTEIN KELCH-LIKE PROTEIN 18 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000002521.3|UniProtKB=F6XSD8 F6XSD8 LOC100180354 PTHR34524:SF6 CALCYPHOSIN CALCYPHOSINE LIKE calmodulin-related#PC00061 CIOIN|Ensembl=ENSCING00000006088.3|UniProtKB=F6YWW9 F6YWW9 PTHR42884:SF3 PROPROTEIN CONVERTASE SUBTILISIN/KEXIN-RELATED FURIN-LIKE PROTEASE 1, ISOFORMS 1_1-X_2 hydrolase activity#GO:0016787;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;protein processing#GO:0016485;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 bounding membrane of organelle#GO:0098588;trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791;Golgi membrane#GO:0000139 serine protease#PC00203;protein modifying enzyme#PC00260 Activin beta signaling pathway#P06210>FUR1#P06238;Endothelin signaling pathway#P00019>furin#P00575;GBB signaling pathway#P06214>FUR1#P06298;SCW signaling pathway#P06216>FUR1#P06333;DPP-SCW signaling pathway#P06212>FUR1#P06263;DPP signaling pathway#P06213>FUR1#P06290;ALP23B signaling pathway#P06209>FUR1#P06227;Alzheimer disease-amyloid secretase pathway#P00003>Furin#P00105;BMP/activin signaling pathway-drosophila#P06211>Furin#P06244;Alzheimer disease-presenilin pathway#P00004>Furin#P00157;MYO signaling pathway#P06215>FUR1#P06318 CIOIN|Ensembl=ENSCING00000007949.3|UniProtKB=A0A1W3JEA6 A0A1W3JEA6 LOC104265886 PTHR22850:SF214 WD40 REPEAT FAMILY CHROMATIN ASSEMBLY FACTOR 1 P55 SUBUNIT nucleosome binding#GO:0031491;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;histone binding#GO:0042393;binding#GO:0005488;chromatin binding#GO:0003682 protein-DNA complex organization#GO:0071824;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;cellular component organization#GO:0016043;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;protein-containing complex organization#GO:0043933;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;chromatin remodeling#GO:0006338;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000020336.1|UniProtKB=H2XRL4 H2XRL4 LOC100186011 PTHR23050:SF536 CALCIUM BINDING PROTEIN EF-HAND DOMAIN-CONTAINING PROTEIN cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488 calmodulin-related#PC00061 B cell activation#P00010>Calmodulin#P00375;Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Calmodulin#P00755;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Phosphorylase b kinase#P00716;T cell activation#P00053>Calmodulin#P01305 CIOIN|Ensembl=ENSCING00000003116.3|UniProtKB=F6RCT7 F6RCT7 LOC113474384 PTHR11071:SF561 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE D-RELATED peptidyl-prolyl cis-trans isomerase activity#GO:0003755;isomerase activity#GO:0016853;catalytic activity, acting on a protein#GO:0140096;binding#GO:0005488;catalytic activity#GO:0003824;peptide binding#GO:0042277;amide binding#GO:0033218 macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein peptidyl-prolyl isomerization#GO:0000413;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein folding#GO:0006457;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 chaperone#PC00072 CIOIN|Ensembl=ENSCING00000024958.1|UniProtKB=H2XLD2 H2XLD2 PTHR16165:SF5 NXPE FAMILY MEMBER NXPE FAMILY MEMBER 3 CIOIN|Ensembl=ENSCING00000007750.3|UniProtKB=Q4H3K3 Q4H3K3 Ci-Fli_ERG2 PTHR11849:SF304 ETS DNA-BINDING PROTEIN D-ETS-3 transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 CIOIN|Ensembl=ENSCING00000023452.1|UniProtKB=F6XUL4 F6XUL4 PTHR43969:SF9 GLUTATHIONE S TRANSFERASE D10, ISOFORM A-RELATED GLUTATHIONE S TRANSFERASE D10, ISOFORM A-RELATED glutathione transferase activity#GO:0004364;transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824 sulfur compound metabolic process#GO:0006790;nitrogen compound metabolic process#GO:0006807;peptide metabolic process#GO:0006518;cellular modified amino acid metabolic process#GO:0006575;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular process#GO:0009987;glutathione metabolic process#GO:0006749;amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000006709.3|UniProtKB=F7AR48 F7AR48 PTHR23333:SF4 UBX DOMAIN CONTAINING PROTEIN UBX DOMAIN-CONTAINING PROTEIN 11 protein binding#GO:0005515;ubiquitin-like protein binding#GO:0032182;binding#GO:0005488;ubiquitin binding#GO:0043130 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 protein-binding activity modulator#PC00095 CIOIN|Ensembl=ENSCING00000004639.3|UniProtKB=F6RMU1 F6RMU1 PTHR10527:SF1 IMPORTIN BETA IMPORTIN SUBUNIT BETA-1 signal sequence binding#GO:0005048;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277 cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;protein localization to nucleus#GO:0034504;nitrogen compound transport#GO:0071705;establishment of protein localization to organelle#GO:0072594;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;protein import into nucleus#GO:0006606;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;protein localization to organelle#GO:0033365;intracellular transport#GO:0046907;nuclear transport#GO:0051169;import into nucleus#GO:0051170 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transporter#PC00227 CIOIN|Ensembl=ENSCING00000016466.2|UniProtKB=F6Z630 F6Z630 PTHR11567:SF211 ACID PHOSPHATASE-RELATED PROSTATIC ACID PHOSPHATASE hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 cellular metabolic process#GO:0044237;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;dephosphorylation#GO:0016311;metabolic process#GO:0008152 metabolite interconversion enzyme#PC00262;phosphatase#PC00181 CIOIN|Ensembl=ENSCING00000012282.2|UniProtKB=F7BEQ8 F7BEQ8 PTHR23254:SF15 EIF4G DOMAIN PROTEIN POLYADENYLATE-BINDING PROTEIN-INTERACTING PROTEIN 1 nucleic acid binding#GO:0003676;translation regulator activity#GO:0045182;translation regulator activity, nucleic acid binding#GO:0090079;binding#GO:0005488;organic cyclic compound binding#GO:0097159 regulation of protein metabolic process#GO:0051246;regulation of amide metabolic process#GO:0034248;regulation of nitrogen compound metabolic process#GO:0051171;regulation of translational initiation#GO:0006446;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biosynthetic process#GO:0009889;post-transcriptional regulation of gene expression#GO:0010608;biological regulation#GO:0065007;regulation of translation#GO:0006417;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000004587.3|UniProtKB=F6WPY5 F6WPY5 LOC100178162 PTHR10534:SF2 PYRIDOXAL KINASE PYRIDOXAL KINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301 cellular aromatic compound metabolic process#GO:0006725;organic hydroxy compound metabolic process#GO:1901615;heterocycle metabolic process#GO:0046483;organophosphate biosynthetic process#GO:0090407;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic hydroxy compound biosynthetic process#GO:1901617;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;heterocycle biosynthetic process#GO:0018130;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;pyridine-containing compound metabolic process#GO:0072524;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;small molecule biosynthetic process#GO:0044283;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 kinase#PC00137 Vitamin B6 metabolism#P02787>Pyridoxal kinase#P03244;Pyridoxal phosphate salvage pathway#P02770>Pyridoxal kinase#P03121;Pyridoxal phosphate salvage pathway#P02770>Pyridoxamine kinase#P03122 CIOIN|Ensembl=ENSCING00000009539.3|UniProtKB=F6UWX3 F6UWX3 LOC100187162 PTHR23073:SF31 26S PROTEASOME REGULATORY SUBUNIT 26S PROTEASOME REGULATORY SUBUNIT 10B ATP-dependent activity#GO:0140657 regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;protein catabolic process#GO:0030163;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of cellular component organization#GO:0051128;regulation of RNA biosynthetic process#GO:2001141;modification-dependent macromolecule catabolic process#GO:0043632;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of cellular component biogenesis#GO:0044087;proteolysis#GO:0006508;proteasomal protein catabolic process#GO:0010498;positive regulation of biological process#GO:0048518;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;response to endoplasmic reticulum stress#GO:0034976;macromolecule metabolic process#GO:0043170;ERAD pathway#GO:0036503;response to organonitrogen compound#GO:0010243;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;ubiquitin-dependent protein catabolic process#GO:0006511;response to nitrogen compound#GO:1901698;response to stress#GO:0006950;regulation of cellular process#GO:0050794;cellular response to stress#GO:0033554;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of transcription by RNA polymerase II#GO:0006357;organonitrogen compound catabolic process#GO:1901565;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of protein-containing complex assembly#GO:0043254;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;catabolic process#GO:0009056;regulation of gene expression#GO:0010468;organic substance catabolic process#GO:1901575;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular component biogenesis#GO:0044089;protein metabolic process#GO:0019538;metabolic process#GO:0008152;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;regulation of DNA-templated transcription#GO:0006355;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;organonitrogen compound metabolic process#GO:1901564;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;regulation of cellular biosynthetic process#GO:0031326;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;positive regulation of RNA metabolic process#GO:0051254 cytoplasm#GO:0005737;peptidase complex#GO:1905368;protein-containing complex#GO:0032991;proteasome accessory complex#GO:0022624;proteasome regulatory particle#GO:0005838;catalytic complex#GO:1902494;endopeptidase complex#GO:1905369;proteasome complex#GO:0000502;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 protease#PC00190;protein modifying enzyme#PC00260 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489 CIOIN|Ensembl=ENSCING00000003949.3|UniProtKB=F6ZL94 F6ZL94 LOC100181041 PTHR10807:SF73 MYOTUBULARIN-RELATED LD06050P hydrolase activity, acting on ester bonds#GO:0016788;phosphatase binding#GO:0019902;phosphatase activity#GO:0016791;binding#GO:0005488;catalytic activity#GO:0003824;phosphatidylinositol-3,5-bisphosphate phosphatase activity#GO:0106018;hydrolase activity#GO:0016787;enzyme binding#GO:0019899;protein binding#GO:0005515;protein phosphatase binding#GO:0019903;phosphoric ester hydrolase activity#GO:0042578 lipid metabolic process#GO:0006629;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of catabolic process#GO:0009894;lipid modification#GO:0030258;phospholipid metabolic process#GO:0006644;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;glycerolipid metabolic process#GO:0046486;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;phospholipid dephosphorylation#GO:0046839;phosphatidylinositol dephosphorylation#GO:0046856;regulation of autophagy#GO:0010506;negative regulation of cellular catabolic process#GO:0031330;cellular metabolic process#GO:0044237;glycerophospholipid metabolic process#GO:0006650;phosphatidylinositol metabolic process#GO:0046488;negative regulation of metabolic process#GO:0009892;regulation of cellular catabolic process#GO:0031329;negative regulation of autophagy#GO:0010507;cellular process#GO:0009987;primary metabolic process#GO:0044238;negative regulation of catabolic process#GO:0009895;regulation of cellular process#GO:0050794;dephosphorylation#GO:0016311;biological regulation#GO:0065007;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;phosphatase#PC00181 CIOIN|Ensembl=ENSCING00000009410.3|UniProtKB=F6TM19 F6TM19 LOC100178377 PTHR10372:SF27 PLAKOPHILLIN-RELATED ADHERENS JUNCTION PROTEIN P120 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cell junction#GO:0030054;membrane-bounded organelle#GO:0043227;adherens junction#GO:0005912;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 intermediate filament binding protein#PC00130;intermediate filament#PC00129 CIOIN|Ensembl=ENSCING00000004854.3|UniProtKB=F6TYP3 F6TYP3 PTHR10924:SF6 MAJOR FACILITATOR SUPERFAMILY PROTEIN-RELATED SOLUTE CARRIER FAMILY 49 MEMBER A3 cellular anatomical entity#GO:0110165;membrane#GO:0016020 secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000009622.3|UniProtKB=F6ZUU0 F6ZUU0 PTHR24031:SF2 RNA HELICASE ATP-DEPENDENT RNA HELICASE DDX55 intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA helicase#PC00032 CIOIN|Ensembl=ENSCING00000021379.1|UniProtKB=H2Y169 H2Y169 PTHR18884:SF126 SEPTIN SEPTIN-7 GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824 localization#GO:0051179;cell division#GO:0051301;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;cytoskeleton-dependent cytokinesis#GO:0061640;cell cycle process#GO:0022402;cell cycle#GO:0007049;cellular process#GO:0009987;cytokinesis#GO:0000910;protein localization#GO:0008104 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;cell division site#GO:0032153;cell cortex#GO:0005938;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085 CIOIN|Ensembl=ENSCING00000002098.3|UniProtKB=F6ZRL9 F6ZRL9 LOC100175118 PTHR14191:SF3 PDZ DOMAIN CONTAINING PROTEIN NA(+)_H(+) EXCHANGE REGULATORY COFACTOR-LIKE PROTEIN NRFL-1 protein-membrane adaptor activity#GO:0043495;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 localization#GO:0051179;protein localization to plasma membrane#GO:0072659;protein localization to cell periphery#GO:1990778;localization within membrane#GO:0051668;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;protein localization to membrane#GO:0072657;cellular process#GO:0009987;protein localization#GO:0008104 plasma membrane region#GO:0098590;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;apical part of cell#GO:0045177;plasma membrane#GO:0005886;apical plasma membrane#GO:0016324 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000001721.3|UniProtKB=F6TVX2 F6TVX2 mT PTHR11267:SF199 T-BOX PROTEIN-RELATED T-BOX PROTEIN 36-RELATED sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cell fate commitment#GO:0045165;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;cell fate specification#GO:0001708;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;Rel homology transcription factor#PC00252;immunoglobulin fold transcription factor#PC00251 CIOIN|Ensembl=ENSCING00000000362.3|UniProtKB=F6VRH3 F6VRH3 LOC100183259 PTHR19858:SF0 WD40 REPEAT PROTEIN PERIODIC TRYPTOPHAN PROTEIN 2 HOMOLOG cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;RNA processing#GO:0006396;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;protein-RNA complex assembly#GO:0022618;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;ribosome biogenesis#GO:0042254;non-membrane-bounded organelle assembly#GO:0140694;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;protein-RNA complex organization#GO:0071826;maturation of SSU-rRNA#GO:0030490;ribosomal small subunit biogenesis#GO:0042274 membrane-enclosed lumen#GO:0031974;small-subunit processome#GO:0032040;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;nuclear lumen#GO:0031981;90S preribosome#GO:0030686;nuclear protein-containing complex#GO:0140513 CIOIN|Ensembl=ENSCING00000022168.1|UniProtKB=H2Y306 H2Y306 PTHR22768:SF0 DNA REPLICATION COMPLEX GINS PROTEIN PSF3 DNA REPLICATION COMPLEX GINS PROTEIN PSF3 cellular aromatic compound metabolic process#GO:0006725;nuclear DNA replication#GO:0033260;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;cell cycle process#GO:0022402;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;mitotic cell cycle process#GO:1903047;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mitotic cell cycle#GO:0000278;mitotic DNA replication initiation#GO:1902975;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;mitotic DNA replication#GO:1902969;DNA-templated DNA replication#GO:0006261;cell cycle#GO:0007049;DNA replication#GO:0006260;DNA replication initiation#GO:0006270;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259;cell cycle DNA replication#GO:0044786 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-DNA complex#GO:0032993;DNA replication preinitiation complex#GO:0031261;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular anatomical structure#GO:0005622;GINS complex#GO:0000811;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 CIOIN|Ensembl=ENSCING00000023683.1|UniProtKB=H2XV07 H2XV07 LOC100187411 PTHR11616:SF321 SODIUM/CHLORIDE DEPENDENT TRANSPORTER SODIUM-DEPENDENT NUTRIENT AMINO ACID TRANSPORTER 1-RELATED inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;organic acid:sodium symporter activity#GO:0005343;organic acid transmembrane transporter activity#GO:0005342;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;organic anion transmembrane transporter activity#GO:0008514;monoatomic cation transmembrane transporter activity#GO:0008324;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;amino acid:sodium symporter activity#GO:0005283;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;metal ion transmembrane transporter activity#GO:0046873;active monoatomic ion transmembrane transporter activity#GO:0022853;amino acid transmembrane transporter activity#GO:0015171;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;organic anion transport#GO:0015711;amino acid transport#GO:0006865;organic acid transport#GO:0015849;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;amino acid import across plasma membrane#GO:0089718;carboxylic acid transmembrane transport#GO:1905039;localization#GO:0051179;organic substance transport#GO:0071702;import across plasma membrane#GO:0098739;amino acid transmembrane transport#GO:0003333;sodium ion transport#GO:0006814;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transport#GO:0006812;organic acid transmembrane transport#GO:1903825;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;import into cell#GO:0098657;sodium ion transmembrane transport#GO:0035725 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 primary active transporter#PC00068;transporter#PC00227 Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>CHT1#P01084 CIOIN|Ensembl=ENSCING00000025066.1|UniProtKB=H2XK76 H2XK76 PTHR45740:SF17 POLY [ADP-RIBOSE] POLYMERASE POLY [ADP-RIBOSE] POLYMERASE TANKYRASE-2-LIKE transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;pentosyltransferase activity#GO:0016763 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000005227.3|UniProtKB=F6YI57 F6YI57 PTHR45883:SF2 HSC70-INTERACTING PROTEIN HSC70-INTERACTING PROTEIN protein binding#GO:0005515;heat shock protein binding#GO:0031072;protein-folding chaperone binding#GO:0051087;binding#GO:0005488;Hsp70 protein binding#GO:0030544 macromolecule biosynthetic process#GO:0009059;chaperone-mediated protein folding#GO:0061077;chaperone cofactor-dependent protein refolding#GO:0051085;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein folding#GO:0006457;'de novo' protein folding#GO:0006458;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 CIOIN|Ensembl=ENSCING00000019222.1|UniProtKB=H2XV08 H2XV08 LOC100186070 PTHR24020:SF87 COLLAGEN ALPHA COLLAGEN ALPHA-1(VI) CHAIN-LIKE external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 CIOIN|Ensembl=ENSCING00000007276.3|UniProtKB=F6SVR6 F6SVR6 LOC100180557 PTHR28671:SF3 COILED-COIL DOMAIN-CONTAINING PROTEIN 169 COILED-COIL DOMAIN-CONTAINING PROTEIN 169 CIOIN|Ensembl=ENSCING00000009557.3|UniProtKB=F6U7Z2 F6U7Z2 LOC100184880 PTHR23074:SF17 AAA DOMAIN-CONTAINING FIDGETIN-LIKE PROTEIN 1 pyrophosphatase activity#GO:0016462;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;ATP hydrolysis activity#GO:0016887 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 CIOIN|Ensembl=ENSCING00000018224.1|UniProtKB=H2XK66 H2XK66 LOC100179671 PTHR14679:SF1 GEM-ASSOCIATED PROTEIN 7 GEM-ASSOCIATED PROTEIN 7 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;RNA processing#GO:0006396;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;protein-RNA complex assembly#GO:0022618;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;spliceosomal snRNP assembly#GO:0000387;organic substance metabolic process#GO:0071704;mRNA splicing, via spliceosome#GO:0000398;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;protein-containing complex organization#GO:0043933;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;ribonucleoprotein complex biogenesis#GO:0022613;mRNA processing#GO:0006397;protein-RNA complex organization#GO:0071826;RNA splicing, via transesterification reactions#GO:0000375 protein-containing complex#GO:0032991;Sm-like protein family complex#GO:0120114 CIOIN|Ensembl=ENSCING00000009615.3|UniProtKB=F7ACY9 F7ACY9 LOC100184759 PTHR36978:SF4 P-LOOP CONTAINING NUCLEOTIDE TRIPHOSPHATE HYDROLASE P-LOOP CONTAINING NUCLEOSIDE TRIPHOSPHATE HYDROLASE PROTEIN metabolite interconversion enzyme#PC00262;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000007225.3|UniProtKB=F6VKZ4 F6VKZ4 PTHR23405:SF4 MAINTENANCE OF KILLER 16 MAK16 PROTEIN-RELATED PROTEIN MAK16 HOMOLOG cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;ribosomal large subunit biogenesis#GO:0042273;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;maturation of 5.8S rRNA#GO:0000460;maturation of LSU-rRNA#GO:0000470;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;preribosome, large subunit precursor#GO:0030687;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;nuclear lumen#GO:0031981 CIOIN|Ensembl=ENSCING00000007427.3|UniProtKB=F7B7V5 F7B7V5 LOC100185679 PTHR11245:SF6 STANNIOCALCIN DUF19 DOMAIN-CONTAINING PROTEIN inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;intracellular monoatomic cation homeostasis#GO:0030003;homeostatic process#GO:0042592;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic ion homeostasis#GO:0006873;chemical homeostasis#GO:0048878;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;intracellular calcium ion homeostasis#GO:0006874;monoatomic ion homeostasis#GO:0050801 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 peptide hormone#PC00179 CIOIN|Ensembl=ENSCING00000020253.1|UniProtKB=H2Y167 H2Y167 zf(tim10_ddp)-2 PTHR19338:SF0 TRANSLOCASE OF INNER MITOCHONDRIAL MEMBRANE 13 HOMOLOG MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM13 CIOIN|Ensembl=ENSCING00000019291.1|UniProtKB=H2XTT0 H2XTT0 LOC100185215 PTHR13292:SF0 AUTOPHAGY-RELATED PROTEIN 101 AUTOPHAGY-RELATED PROTEIN 101 enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;binding#GO:0005488;kinase binding#GO:0019900 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;macroautophagy#GO:0016236;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular process#GO:0009987;organelle assembly#GO:0070925;process utilizing autophagic mechanism#GO:0061919;cellular component organization or biogenesis#GO:0071840;vacuole organization#GO:0007033;organelle organization#GO:0006996;catabolic process#GO:0009056;autophagosome assembly#GO:0000045;autophagy#GO:0006914;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;phagophore assembly site#GO:0000407;catalytic complex#GO:1902494;transferase complex#GO:1990234;serine/threonine protein kinase complex#GO:1902554;protein kinase complex#GO:1902911;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695 CIOIN|Ensembl=ENSCING00000009037.3|UniProtKB=F6R798 F6R798 PTHR10110:SF98 SODIUM/HYDROGEN EXCHANGER SODIUM_HYDROGEN EXCHANGER secondary active transmembrane transporter activity#GO:0015291;inorganic molecular entity transmembrane transporter activity#GO:0015318;antiporter activity#GO:0015297;transmembrane transporter activity#GO:0022857;potassium ion transmembrane transporter activity#GO:0015079;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;proton transmembrane transporter activity#GO:0015078;metal cation:proton antiporter activity#GO:0051139;active monoatomic ion transmembrane transporter activity#GO:0022853;monoatomic cation transmembrane transporter activity#GO:0008324;monoatomic ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;inorganic cation transmembrane transporter activity#GO:0022890;transporter activity#GO:0005215 regulation of intracellular pH#GO:0051453;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;homeostatic process#GO:0042592;inorganic ion transmembrane transport#GO:0098660;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;cellular process#GO:0009987;intracellular chemical homeostasis#GO:0055082;monoatomic ion homeostasis#GO:0050801;localization#GO:0051179;regulation of pH#GO:0006885;import across plasma membrane#GO:0098739;sodium ion transport#GO:0006814;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;intracellular monoatomic cation homeostasis#GO:0030003;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;monoatomic cation transport#GO:0006812;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion transport#GO:0006811;regulation of cellular pH#GO:0030641;import into cell#GO:0098657;monoatomic cation transmembrane transport#GO:0098655;sodium ion transmembrane transport#GO:0035725;potassium ion transport#GO:0006813 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000021399.1|UniProtKB=H2XQK9 H2XQK9 PTHR10887:SF364 DNA2/NAM7 HELICASE FAMILY REGULATOR OF NONSENSE TRANSCRIPTS 1 catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;helicase activity#GO:0004386;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;heterocycle catabolic process#GO:0046700;RNA metabolic process#GO:0016070;nucleobase-containing compound metabolic process#GO:0006139;cellular nitrogen compound catabolic process#GO:0044270;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;mRNA catabolic process#GO:0006402;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;organic substance catabolic process#GO:1901575;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;negative regulation of biosynthetic process#GO:0009890;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;nuclear-transcribed mRNA catabolic process#GO:0000956;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;nuclear-transcribed mRNA catabolic process, nonsense-mediated decay#GO:0000184;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;nucleobase-containing compound catabolic process#GO:0034655;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 RNA helicase#PC00032 CIOIN|Ensembl=ENSCING00000007044.3|UniProtKB=F6ZCC7 F6ZCC7 PTHR32083:SF34 CILIA AND FLAGELLA-ASSOCIATED PROTEIN 58-RELATED COILED-COIL DOMAIN-CONTAINING PROTEIN 146 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 structural protein#PC00211 CIOIN|Ensembl=ENSCING00000008071.3|UniProtKB=F6Z781 F6Z781 PTHR11073:SF2 CALRETICULIN AND CALNEXIN CALRETICULIN cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488 protein catabolic process#GO:0030163;gene expression#GO:0010467;organonitrogen compound catabolic process#GO:1901565;biosynthetic process#GO:0009058;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;macromolecule catabolic process#GO:0009057;response to endoplasmic reticulum stress#GO:0034976;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein maturation#GO:0051604;ERAD pathway#GO:0036503;cellular biosynthetic process#GO:0044249;response to organonitrogen compound#GO:0010243;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;protein folding#GO:0006457;cellular response to stress#GO:0033554 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 chaperone#PC00072 CIOIN|Ensembl=ENSCING00000011877.2|UniProtKB=F6Z1X1 F6Z1X1 LOC113474003 PTHR24305:SF166 CYTOCHROME P450 CYTOCHROME P450 12A4, MITOCHONDRIAL-RELATED oxygenase#PC00177 CIOIN|Ensembl=ENSCING00000020809.1|UniProtKB=H2Y0X5 H2Y0X5 PTHR11820:SF7 ACYLPYRUVASE ACYLPYRUVASE FAHD1, MITOCHONDRIAL hydrolase activity#GO:0016787;catalytic activity#GO:0003824 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000018427.1|UniProtKB=H2XYU7 H2XYU7 PTHR20873:SF0 L-SERYL-TRNA(SEC) KINASE L-SERYL-TRNA(SEC) KINASE tRNA binding#GO:0000049;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;transferase activity#GO:0016740;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 CIOIN|Ensembl=ENSCING00000018266.1|UniProtKB=H2XLS9 H2XLS9 PTHR33936:SF24 PROTEIN CBG17840 C2H2-TYPE DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000011420.2|UniProtKB=F7AX27 F7AX27 LOC100176776 PTHR23089:SF18 HISTIDINE TRIAD HIT PROTEIN ADENOSINE 5'-MONOPHOSPHORAMIDASE HINT2 hydrolase activity#GO:0016787;catalytic activity#GO:0003824 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 nucleotide phosphatase#PC00173 CIOIN|Ensembl=ENSCING00000016152.2|UniProtKB=F6SU13 F6SU13 rl32 PTHR23413:SF1 60S RIBOSOMAL PROTEIN L32 AND DNA-DIRECTED RNA POLYMERASE II, SUBUNIT N RIBOSOMAL PROTEIN L32 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic large ribosomal subunit#GO:0022625;large ribosomal subunit#GO:0015934;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000007451.3|UniProtKB=F6YJ36 F6YJ36 PTHR24256:SF470 TRYPTASE-RELATED INACTIVE CLIP DOMAIN-CONTAINING SERINE PROTEASE A30 serine protease#PC00203;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000018814.1|UniProtKB=H2Y143 H2Y143 LOC100181469 PTHR28652:SF2 TRANSMEMBRANE PROTEIN 59-LIKE PROTEIN TRANSMEMBRANE PROTEIN 59-LIKE PROTEIN CIOIN|Ensembl=ENSCING00000008864.3|UniProtKB=F6R2V7 F6R2V7 PTHR13146:SF0 FAMILY NOT NAMED SOLUTE CARRIER FAMILY 35 MEMBER F6 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;membrane#GO:0016020;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000003956.3|UniProtKB=F6ZLA6 F6ZLA6 PTHR23503:SF132 SOLUTE CARRIER FAMILY 2 SOLUTE CARRIER FAMILY 2, FACILITATED GLUCOSE TRANSPORTER MEMBER 5-LIKE transmembrane transporter activity#GO:0022857;sugar transmembrane transporter activity#GO:0051119;transporter activity#GO:0005215;carbohydrate transmembrane transporter activity#GO:0015144 localization#GO:0051179;organic substance transport#GO:0071702;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;organic anion transport#GO:0015711;transport#GO:0006810;vitamin transport#GO:0051180;glucose transmembrane transport#GO:1904659;cellular process#GO:0009987;carbohydrate transmembrane transport#GO:0034219;carbohydrate transport#GO:0008643 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000021430.1|UniProtKB=H2XK55 H2XK55 PTHR13174:SF3 D-GLUCURONYL C5-EPIMERASE D-GLUCURONYL C5-EPIMERASE racemase and epimerase activity, acting on carbohydrates and derivatives#GO:0016857;isomerase activity#GO:0016853;catalytic activity#GO:0003824 glycoprotein biosynthetic process#GO:0009101;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;sulfur compound metabolic process#GO:0006790;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;proteoglycan metabolic process#GO:0006029;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;proteoglycan biosynthetic process#GO:0030166;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 isomerase#PC00135;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000011546.2|UniProtKB=F6TCG6 F6TCG6 LOC100175995 PTHR15857:SF0 COMM DOMAIN CONTAINING PROTEIN 2 COMM DOMAIN-CONTAINING PROTEIN 2 CIOIN|Ensembl=ENSCING00000005326.3|UniProtKB=F7BPC9 F7BPC9 PTHR46370:SF1 GPALPP MOTIFS-CONTAINING PROTEIN 1 GPALPP MOTIFS-CONTAINING PROTEIN 1 CIOIN|Ensembl=ENSCING00000012821.2|UniProtKB=F6W3K8 F6W3K8 LOC100179402 PTHR23291:SF50 BAX INHIBITOR-RELATED PROTEIN LIFEGUARD 4 cellular anatomical entity#GO:0110165;membrane#GO:0016020 ion channel#PC00133;transporter#PC00227 CIOIN|Ensembl=ENSCING00000001453.3|UniProtKB=F6VBZ6 F6VBZ6 PTHR14513:SF0 PROTECTION OF TELOMERES 1 PROTECTION OF TELOMERES PROTEIN 1 sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;single-stranded telomeric DNA binding#GO:0043047;molecular function regulator activity#GO:0098772;single-stranded DNA binding#GO:0003697;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;telomeric DNA binding#GO:0042162;enzyme inhibitor activity#GO:0004857;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234 cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of nitrogen compound metabolic process#GO:0051171;telomere organization#GO:0032200;regulation of DNA metabolic process#GO:0051052;regulation of cellular component organization#GO:0051128;regulation of telomere maintenance#GO:0032204;regulation of catalytic activity#GO:0050790;nucleobase-containing compound metabolic process#GO:0006139;telomere maintenance#GO:0000723;regulation of biological process#GO:0050789;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;regulation of molecular function#GO:0065009;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA metabolic process#GO:0051053;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of chromosome organization#GO:0033044;heterocycle metabolic process#GO:0046483;negative regulation of biosynthetic process#GO:0009890;telomere capping#GO:0016233;macromolecule metabolic process#GO:0043170;regulation of organelle organization#GO:0033043;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of transferase activity#GO:0051338;negative regulation of catalytic activity#GO:0043086;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;negative regulation of molecular function#GO:0044092;DNA metabolic process#GO:0006259 nuclear telomere cap complex#GO:0000783;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-DNA complex#GO:0032993;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome, telomeric region#GO:0000781;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;chromosomal region#GO:0098687;nuclear protein-containing complex#GO:0140513 DNA metabolism protein#PC00009 CIOIN|Ensembl=ENSCING00000009968.3|UniProtKB=A0A1W2WP76 A0A1W2WP76 LOC100181445 PTHR31898:SF1 TRANSMEMBRANE PROTEIN 136 TLC DOMAIN-CONTAINING PROTEIN 5 CIOIN|Ensembl=ENSCING00000003585.3|UniProtKB=F6Y8A2 F6Y8A2 LOC100181177 PTHR44329:SF291 SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED PROTEIN KINASE DOMAIN-CONTAINING PROTEIN MAP kinase kinase kinase activity#GO:0004709;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000002787.3|UniProtKB=F6XMZ3 F6XMZ3 LOC100185077 PTHR47174:SF3 BRIDGING INTEGRATOR 3 BRIDGING INTEGRATOR 3 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000007327.3|UniProtKB=F6YKG6 F6YKG6 LOC100175070 PTHR45981:SF3 LD02310P LD02310P transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein polyubiquitination#GO:0000209;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000009319.3|UniProtKB=F6ZMG2 F6ZMG2 PTHR12103:SF38 5'-NUCLEOTIDASE DOMAIN-CONTAINING 5'-NUCLEOTIDASE DOMAIN-CONTAINING PROTEIN 1 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;5'-nucleotidase activity#GO:0008253;catalytic activity#GO:0003824;nucleotidase activity#GO:0008252;phosphoric ester hydrolase activity#GO:0042578 nucleotide phosphatase#PC00173;phosphatase#PC00181;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000008159.3|UniProtKB=F6UR44 F6UR44 PTHR48041:SF78 ABC TRANSPORTER G FAMILY MEMBER 28 ABC TRANSPORTER EXPRESSED IN TRACHEA, ISOFORM A transmembrane transporter activity#GO:0022857;primary active transmembrane transporter activity#GO:0015399;ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 localization#GO:0051179;cellular process#GO:0009987;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 ATP-binding cassette (ABC) transporter#PC00003;transporter#PC00227 CIOIN|Ensembl=ENSCING00000007321.3|UniProtKB=F6Z382 F6Z382 LOC100178050 PTHR42985:SF45 SODIUM-COUPLED MONOCARBOXYLATE TRANSPORTER SODIUM_IODIDE COTRANSPORTER-LIKE symporter activity#GO:0015293;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 localization#GO:0051179;monoatomic cation transport#GO:0006812;sodium ion transport#GO:0006814;metal ion transport#GO:0030001;establishment of localization#GO:0051234;monoatomic ion transport#GO:0006811;transport#GO:0006810 secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000007805.3|UniProtKB=F6WHS2 F6WHS2 LOC100178371 PTHR31516:SF17 STABILIZER OF AXONEMAL MICROTUBULES 2 STABILIZER OF AXONEMAL MICROTUBULES 2 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;microtubule binding#GO:0008017;tubulin binding#GO:0015631;binding#GO:0005488 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 CIOIN|Ensembl=ENSCING00000006903.2|UniProtKB=F6YAA4 F6YAA4 PTHR12121:SF37 CARBON CATABOLITE REPRESSOR PROTEIN 4 2',5'-PHOSPHODIESTERASE 12 catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;catalytic activity#GO:0003824;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters#GO:0016796;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity#GO:0016787;3'-5'-RNA exonuclease activity#GO:0000175;3'-5' exonuclease activity#GO:0008408;exonuclease activity#GO:0004527;RNA nuclease activity#GO:0004540 negative regulation of gene expression#GO:0010629;regulation of catabolic process#GO:0009894;heterocycle catabolic process#GO:0046700;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;nucleobase-containing compound metabolic process#GO:0006139;RNA destabilization#GO:0050779;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;regulation of RNA stability#GO:0043487;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;positive regulation of mRNA catabolic process#GO:0061014;regulation of cellular process#GO:0050794;post-transcriptional regulation of gene expression#GO:0010608;positive regulation of catabolic process#GO:0009896;mRNA destabilization#GO:0061157;nucleobase-containing compound catabolic process#GO:0034655;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;regulation of mRNA stability#GO:0043488;RNA metabolic process#GO:0016070;positive regulation of cellular catabolic process#GO:0031331;cellular nitrogen compound catabolic process#GO:0044270;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;mRNA catabolic process#GO:0006402;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;regulation of gene expression#GO:0010468;organic substance catabolic process#GO:1901575;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;positive regulation of mRNA metabolic process#GO:1903313;heterocycle metabolic process#GO:0046483;negative regulation of biosynthetic process#GO:0009890;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;positive regulation of RNA metabolic process#GO:0051254 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 mRNA polyadenylation factor#PC00146 CIOIN|Ensembl=ENSCING00000024813.1|UniProtKB=F6XLJ0 F6XLJ0 PTHR11481:SF60 IMMUNOGLOBULIN FC RECEPTOR IG-LIKE DOMAIN-CONTAINING PROTEIN external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 CIOIN|Ensembl=ENSCING00000012330.2|UniProtKB=F7ABS5 F7ABS5 LOC100184287 PTHR13720:SF13 WD-40 REPEAT PROTEIN CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 251 membrane-bounded organelle#GO:0043227;motile cilium#GO:0031514;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;cilium#GO:0005929;organelle#GO:0043226 cytoskeletal protein#PC00085;microtubule or microtubule-binding cytoskeletal protein#PC00157 CIOIN|Ensembl=ENSCING00000007955.3|UniProtKB=F6Z839 F6Z839 PTHR22984:SF25 SERINE/THREONINE-PROTEIN KINASE PIM PROTEIN KINASE DOMAIN-CONTAINING PROTEIN transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;phosphorylation#GO:0016310;protein phosphorylation#GO:0006468;cellular process#GO:0009987;protein metabolic process#GO:0019538;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000007700.3|UniProtKB=F6RW91 F6RW91 PTHR45623:SF14 CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 3-RELATED-RELATED CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 1 ATP-dependent activity, acting on DNA#GO:0008094;nucleic acid binding#GO:0003676;binding#GO:0005488;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;ribonucleoside triphosphate phosphatase activity#GO:0017111;ATP hydrolysis activity#GO:0016887;histone binding#GO:0042393;pyrophosphatase activity#GO:0016462;ATP-dependent activity#GO:0140657;chromatin binding#GO:0003682;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity, acting on DNA#GO:0140097;protein-containing complex binding#GO:0044877 cellular component organization or biogenesis#GO:0071840;protein-DNA complex organization#GO:0071824;nucleosome organization#GO:0034728;protein-containing complex organization#GO:0043933;chromatin organization#GO:0006325;cellular component organization#GO:0016043;chromatin remodeling#GO:0006338;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 CIOIN|Ensembl=ENSCING00000001514.3|UniProtKB=F6S888 F6S888 PTHR36978:SF4 P-LOOP CONTAINING NUCLEOTIDE TRIPHOSPHATE HYDROLASE P-LOOP CONTAINING NUCLEOSIDE TRIPHOSPHATE HYDROLASE PROTEIN metabolite interconversion enzyme#PC00262;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000008392.3|UniProtKB=F6XSG2 F6XSG2 LOC100179722 PTHR23040:SF1 FAMILY NOT NAMED OUTER DYNEIN ARM-DOCKING COMPLEX SUBUNIT 4 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000007605.3|UniProtKB=F6ZJN8 F6ZJN8 PTHR10666:SF458 UBIQUITIN POLYUBIQUITIN-C nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159;ubiquitin-like protein ligase binding#GO:0044389;protein binding#GO:0005515;enzyme binding#GO:0019899;ubiquitin protein ligase binding#GO:0031625 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;protein modification by small protein conjugation#GO:0032446;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000007078.3|UniProtKB=F6USH9 F6USH9 PTHR11911:SF111 INOSINE-5-MONOPHOSPHATE DEHYDROGENASE RELATED INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 ribonucleoside triphosphate metabolic process#GO:0009199;cellular aromatic compound metabolic process#GO:0006725;nucleoside triphosphate metabolic process#GO:0009141;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;nucleotide biosynthetic process#GO:0009165;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;purine nucleoside triphosphate biosynthetic process#GO:0009145;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;purine ribonucleoside triphosphate metabolic process#GO:0009205;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;ribonucleoside triphosphate biosynthetic process#GO:0009201;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;nucleoside triphosphate biosynthetic process#GO:0009142;organophosphate metabolic process#GO:0019637;purine nucleoside triphosphate metabolic process#GO:0009144;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 dehydrogenase#PC00092;oxidoreductase#PC00176 De novo purine biosynthesis#P02738>IMP dehydrogenase#P02895 CIOIN|Ensembl=ENSCING00000004730.3|UniProtKB=F6PRY2 F6PRY2 PTHR21737:SF4 POLYGLUTAMINE BINDING PROTEIN 1/MARVEL MEMBRANE-ASSOCIATING DOMAIN CONTAINING 3 SPLICING FACTOR CACTIN cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;mRNA cis splicing, via spliceosome#GO:0045292;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000001909.2|UniProtKB=F7A2M7 F7A2M7 LOC100183291 PTHR46600:SF1 THAP DOMAIN-CONTAINING THAP DOMAIN-CONTAINING PROTEIN 1 zinc finger transcription factor#PC00244 CIOIN|Ensembl=ENSCING00000006525.3|UniProtKB=F6PQL4 F6PQL4 LOC100175647 PTHR11557:SF0 PORPHOBILINOGEN DEAMINASE PORPHOBILINOGEN DEAMINASE transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824 tetrapyrrole metabolic process#GO:0033013;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;pigment metabolic process#GO:0042440;porphyrin-containing compound metabolic process#GO:0006778;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;heterocycle biosynthetic process#GO:0018130;heme biosynthetic process#GO:0006783;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;pigment biosynthetic process#GO:0046148;aromatic compound biosynthetic process#GO:0019438;organic substance metabolic process#GO:0071704;heme metabolic process#GO:0042168;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 deaminase#PC00088;metabolite interconversion enzyme#PC00262;hydrolase#PC00121 Heme biosynthesis#P02746>Hydroxymethylbilane synthase#P02983 CIOIN|Ensembl=ENSCING00000004805.3|UniProtKB=F6R9H9 F6R9H9 LOC100177047 PTHR11547:SF63 ARGININE OR CREATINE KINASE CREATINE KINASE M-TYPE transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301 organophosphate biosynthetic process#GO:0090407;nitrogen compound metabolic process#GO:0006807;cellular modified amino acid metabolic process#GO:0006575;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;organophosphate metabolic process#GO:0019637;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;metabolic process#GO:0008152;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 amino acid kinase#PC00045 CIOIN|Ensembl=ENSCING00000011316.2|UniProtKB=F6XJ57 F6XJ57 PTHR12570:SF65 FAMILY NOT NAMED MAGNESIUM TRANSPORTER NIPA9-RELATED localization#GO:0051179;monoatomic cation transport#GO:0006812;metal ion transport#GO:0030001;establishment of localization#GO:0051234;monoatomic ion transport#GO:0006811;transport#GO:0006810 cellular anatomical entity#GO:0110165;membrane#GO:0016020 secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000020265.1|UniProtKB=H2XUU0 H2XUU0 PTHR43675:SF8 ARSENITE METHYLTRANSFERASE ARSENITE METHYLTRANSFERASE methyltransferase activity#GO:0008168;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824 methyltransferase#PC00155;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000023656.1|UniProtKB=H2Y164 H2Y164 PTHR43851:SF3 FAMILY NOT NAMED COENZYME Q8 CIOIN|Ensembl=ENSCING00000003010.3|UniProtKB=F6QF82 F6QF82 LOC100180927 PTHR36978:SF4 P-LOOP CONTAINING NUCLEOTIDE TRIPHOSPHATE HYDROLASE P-LOOP CONTAINING NUCLEOSIDE TRIPHOSPHATE HYDROLASE PROTEIN metabolite interconversion enzyme#PC00262;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000006921.3|UniProtKB=F6VP00 F6VP00 LOC100180112 PTHR10048:SF34 PHOSPHATIDYLINOSITOL KINASE PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE 3-KINASE CATALYTIC SUBUNIT GAMMA ISOFORM transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301;lipid kinase activity#GO:0001727 lipid metabolic process#GO:0006629;signal transduction#GO:0007165;phospholipid biosynthetic process#GO:0008654;organophosphate biosynthetic process#GO:0090407;phosphatidylinositol biosynthetic process#GO:0006661;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;lipid biosynthetic process#GO:0008610;phosphatidylinositol phosphate biosynthetic process#GO:0046854;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;glycerolipid metabolic process#GO:0046486;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;signaling#GO:0023052;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular response to stimulus#GO:0051716;glycerolipid biosynthetic process#GO:0045017;cellular metabolic process#GO:0044237;cell communication#GO:0007154;glycerophospholipid metabolic process#GO:0006650;phosphatidylinositol metabolic process#GO:0046488;cell motility#GO:0048870;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0043491;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;glycerophospholipid biosynthetic process#GO:0046474;biological regulation#GO:0065007;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;cell migration#GO:0016477 cytoplasm#GO:0005737;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;phosphatidylinositol 3-kinase complex#GO:0005942;catalytic complex#GO:1902494;transferase complex#GO:1990234;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695;extrinsic component of membrane#GO:0019898 kinase#PC00137 PDGF signaling pathway#P00047>PI3K#P01168;Apoptosis signaling pathway#P00006>PI3K#P00310;T cell activation#P00053>PI3K#P01322;Hypoxia response via HIF activation#P00030>PI3K#P00823;Axon guidance mediated by netrin#P00009>PI3K#P00363;EGF receptor signaling pathway#P00018>PI3K#P00557;VEGF signaling pathway#P00056>PI3K#P01413;FGF signaling pathway#P00021>PI3K#P00640;p53 pathway feedback loops 2#P04398>PI3K#P04661;Endothelin signaling pathway#P00019>PI3K#P00577;Integrin signalling pathway#P00034>PI3K#P00936;Angiogenesis#P00005>PI3K#P00236;B cell activation#P00010>PI3K#P00391;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PI3K#P00868;Ras Pathway#P04393>PI3K#P04567;p53 pathway#P00059>PI3K#P04609;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>PI3K#P00900 CIOIN|Ensembl=ENSCING00000004390.3|UniProtKB=F7AUL7 F7AUL7 PTHR12891:SF0 DNA REPAIR/TRANSCRIPTION PROTEIN MET18/MMS19 MMS19 NUCLEOTIDE EXCISION REPAIR PROTEIN HOMOLOG macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000023920.1|UniProtKB=F6QMJ1 F6QMJ1 LOC100177373 PTHR13633:SF3 MITOCHONDRIAL TRANSCRIPTION RESCUE FACTOR 1 MITOCHONDRIAL TRANSCRIPTION RESCUE FACTOR 1 CIOIN|Ensembl=ENSCING00000023242.1|UniProtKB=H2XRV7 H2XRV7 PTHR48225:SF7 HORMA DOMAIN-CONTAINING PROTEIN 1 MEIOSIS-SPECIFIC PROTEIN HOP1 CIOIN|Ensembl=ENSCING00000024178.1|UniProtKB=H2Y107 H2Y107 LOC100176234 PTHR43721:SF3 ELONGATION FACTOR TU-RELATED GTP-BINDING PROTEIN 2 nucleic acid binding#GO:0003676;translation regulator activity#GO:0045182;translation regulator activity, nucleic acid binding#GO:0090079;binding#GO:0005488;organic cyclic compound binding#GO:0097159;translation elongation factor activity#GO:0003746;translation factor activity, RNA binding#GO:0008135 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;translational elongation#GO:0006414;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 translation elongation factor#PC00222;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000002167.3|UniProtKB=F6SSS2 F6SSS2 LOC100181599 PTHR10029:SF3 ACYLPHOSPHATASE ACYLPHOSPHATASE-RELATED pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824 hydrolase#PC00121;phosphatase#PC00181 CIOIN|Ensembl=ENSCING00000019380.1|UniProtKB=H2XY24 H2XY24 LOC100186647 PTHR12791:SF37 GOLGI SNARE BET1-RELATED BET1-LIKE PROTEIN molecular adaptor activity#GO:0060090;SNAP receptor activity#GO:0005484;protein-macromolecule adaptor activity#GO:0030674 endosomal transport#GO:0016197;cellular localization#GO:0051641;transport#GO:0006810;regulation of localization#GO:0032879;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;cytosolic transport#GO:0016482;regulation of vesicle-mediated transport#GO:0060627;retrograde transport, endosome to Golgi#GO:0042147;regulation of biological process#GO:0050789;localization#GO:0051179;regulation of transport#GO:0051049;establishment of localization#GO:0051234;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 SNARE complex#GO:0031201;cytoplasm#GO:0005737;membrane protein complex#GO:0098796;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;membrane#GO:0016020;intracellular anatomical structure#GO:0005622 SNARE protein#PC00034 CIOIN|Ensembl=ENSCING00000019687.1|UniProtKB=H2XQG5 H2XQG5 PTHR11662:SF399 SOLUTE CARRIER FAMILY 17 FI19708P1-RELATED secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000011928.2|UniProtKB=F6VB41 F6VB41 PTHR24034:SF89 EGF-LIKE DOMAIN-CONTAINING PROTEIN COMPLEMENT COMPONENT C1Q RECEPTOR extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 CIOIN|Ensembl=ENSCING00000023078.1|UniProtKB=Q5VJS0 Q5VJS0 ekn1 PTHR46492:SF1 DYNEIN ASSEMBLY FACTOR 4, AXONEMAL DYNEIN AXONEMAL ASSEMBLY FACTOR 4 cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;outer dynein arm assembly#GO:0036158;cell projection organization#GO:0030030;inner dynein arm assembly#GO:0036159;protein-containing complex assembly#GO:0065003;microtubule-based movement#GO:0007018;microtubule cytoskeleton organization#GO:0000226;cellular component organization#GO:0016043;axoneme assembly#GO:0035082;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031;cilium movement#GO:0003341;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;microtubule bundle formation#GO:0001578;axonemal dynein complex assembly#GO:0070286;cytoskeleton organization#GO:0007010;plasma membrane bounded cell projection assembly#GO:0120031 chaperone#PC00072 CIOIN|Ensembl=ENSCING00000024635.1|UniProtKB=H2XVU9 H2XVU9 LOC101242531 PTHR21146:SF0 MEF2B PROTEIN BLOC-1-RELATED COMPLEX SUBUNIT 8 p38 MAPK pathway#P05918>MEF#P06023 CIOIN|Ensembl=ENSCING00000006285.3|UniProtKB=F6V0K9 F6V0K9 LOC100179957 PTHR19282:SF551 TETRASPANIN RE08073P-RELATED cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000013279.2|UniProtKB=F7BLT9 F7BLT9 PTHR45570:SF2 CARBOXYLIC ESTER HYDROLASE ACETYLCHOLINESTERASE 1-LIKE metabolite interconversion enzyme#PC00262;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000021714.1|UniProtKB=H2Y0I5 H2Y0I5 PTHR13914:SF29 PROLINE OXIDASE HYDROXYPROLINE DEHYDROGENASE nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;flavin adenine dinucleotide binding#GO:0050660;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167;oxidoreductase activity#GO:0016491 oxoacid metabolic process#GO:0043436;proteinogenic amino acid metabolic process#GO:0170039;dicarboxylic acid metabolic process#GO:0043648;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;amino acid catabolic process#GO:0009063;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;nitrogen compound metabolic process#GO:0006807;glutamate metabolic process#GO:0006536;alpha-amino acid metabolic process#GO:1901605;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;carboxylic acid metabolic process#GO:0019752;L-amino acid metabolic process#GO:0170033;amino acid metabolic process#GO:0006520;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 oxidase#PC00175;oxidoreductase#PC00176 Huntington disease#P00029>Proline oxidase#G01529 CIOIN|Ensembl=ENSCING00000003785.3|UniProtKB=F7AW82 F7AW82 PTHR22589:SF113 CARNITINE O-ACYLTRANSFERASE CARNITINE O-PALMITOYLTRANSFERASE 1, LIVER ISOFORM-LIKE palmitoyltransferase activity#GO:0016409;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;O-acyltransferase activity#GO:0008374 oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;fatty acid metabolic process#GO:0006631;nitrogen compound metabolic process#GO:0006807;cellular modified amino acid metabolic process#GO:0006575;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transferase#PC00220;acyltransferase#PC00042;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000019105.1|UniProtKB=H2XWX7 H2XWX7 PTHR22906:SF43 PROPERDIN PROPERDIN CIOIN|Ensembl=ENSCING00000013725.2|UniProtKB=F6SPV5 F6SPV5 PTHR11685:SF441 RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING RBR-TYPE E3 UBIQUITIN TRANSFERASE ubiquitin-like protein conjugating enzyme binding#GO:0044390;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;enzyme binding#GO:0019899;protein binding#GO:0005515;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;protein polyubiquitination#GO:0000209;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000020880.1|UniProtKB=F6SNZ5 F6SNZ5 PTHR23023:SF226 DIMETHYLANILINE MONOOXYGENASE FLAVIN-CONTAINING MONOOXYGENASE oxygenase#PC00177;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000005399.2|UniProtKB=F6ZSI5 F6ZSI5 PTHR15261:SF4 THROMBOSPONDIN-TYPE LAMININ G DOMAIN AND EAR REPEAT-CONTAINING THROMBOSPONDIN-TYPE LAMININ G DOMAIN AND EAR REPEAT-CONTAINING PROTEIN regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 intercellular signal molecule#PC00207 CIOIN|Ensembl=ENSCING00000009569.3|UniProtKB=F6TJS8 F6TJS8 PTHR45725:SF3 FORMIN HOMOLOGY 2 FAMILY MEMBER DELPHILIN CIOIN|Ensembl=ENSCING00000003762.3|UniProtKB=F6TIY7 F6TIY7 PTHR24012:SF877 RNA BINDING PROTEIN BRUNO 1, ISOFORM B-RELATED RNA binding#GO:0003723;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159;mRNA 3'-UTR binding#GO:0003730 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;RNA processing#GO:0006396;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;protein-RNA complex assembly#GO:0022618;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;regulation of mRNA processing#GO:0050684;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular component organization#GO:0016043;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;mRNA splice site recognition#GO:0006376;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;regulation of RNA splicing#GO:0043484;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;protein-containing complex organization#GO:0043933;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;ribonucleoprotein complex biogenesis#GO:0022613;biological regulation#GO:0065007;mRNA processing#GO:0006397;protein-RNA complex organization#GO:0071826;RNA splicing, via transesterification reactions#GO:0000375;spliceosomal complex assembly#GO:0000245;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;regulation of metabolic process#GO:0019222;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000003158.3|UniProtKB=F6QIY7 F6QIY7 PTHR11849:SF182 ETS SAM POINTED DOMAIN-CONTAINING ETS TRANSCRIPTION FACTOR transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 PDGF signaling pathway#P00047>Ets#P01167 CIOIN|Ensembl=ENSCING00000022486.1|UniProtKB=H2XUV4 H2XUV4 PTHR24115:SF578 KINESIN-RELATED KINESIN-LIKE PROTEIN KIFC1 pyrophosphatase activity#GO:0016462;cytoskeletal protein binding#GO:0008092;microtubule motor activity#GO:0003777;tubulin binding#GO:0015631;ATP-dependent activity#GO:0140657;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;cytoskeletal motor activity#GO:0003774;microtubule binding#GO:0008017;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;ribonucleoside triphosphate phosphatase activity#GO:0017111;ATP hydrolysis activity#GO:0016887 microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;microtubule associated complex#GO:0005875;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 CIOIN|Ensembl=ENSCING00000018002.1|UniProtKB=H2XSR0 H2XSR0 PTHR24412:SF172 KELCH PROTEIN KELCH-LIKE PROTEIN 10 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000001145.3|UniProtKB=F6YV15 F6YV15 PTHR19423:SF1 SH3 DOMAIN-BINDING PROTEIN 5 SH3 DOMAIN-BINDING PROTEIN 5 enzyme inhibitor activity#GO:0004857;protein kinase regulator activity#GO:0019887;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;protein kinase inhibitor activity#GO:0004860 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;signaling#GO:0023052 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000018722.1|UniProtKB=H2XL96 H2XL96 PTHR22911:SF6 ACYL-MALONYL CONDENSING ENZYME-RELATED SOLUTE CARRIER FAMILY 35 MEMBER G1 cellular anatomical entity#GO:0110165;membrane#GO:0016020 transporter#PC00227 CIOIN|Ensembl=ENSCING00000020245.1|UniProtKB=H2XL09 H2XL09 LOC100180595 PTHR33966:SF1 PROTEIN ODR-4 HOMOLOG PROTEIN ODR-4 HOMOLOG localization#GO:0051179;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;cellular process#GO:0009987;macromolecule localization#GO:0033036;protein localization#GO:0008104 cellular anatomical entity#GO:0110165;endomembrane system#GO:0012505 CIOIN|Ensembl=ENSCING00000005716.3|UniProtKB=F6WPE8 F6WPE8 ephrina-d PTHR11304:SF29 EPHRIN EPHRIN protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 neuron projection guidance#GO:0097485;signal transduction#GO:0007165;neurogenesis#GO:0022008;cell projection organization#GO:0030030;developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cellular anatomical entity morphogenesis#GO:0032989;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;axon guidance#GO:0007411;anatomical structure morphogenesis#GO:0009653;neuron differentiation#GO:0030182;axonogenesis#GO:0007409;plasma membrane bounded cell projection morphogenesis#GO:0120039;signaling#GO:0023052;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;multicellular organism development#GO:0007275;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;cell communication#GO:0007154;cellular process#GO:0009987;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;neuron projection development#GO:0031175;axon development#GO:0061564;enzyme-linked receptor protein signaling pathway#GO:0007167;cell morphogenesis involved in neuron differentiation#GO:0048667;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 membrane-bound signaling molecule#PC00152;intercellular signal molecule#PC00207 CIOIN|Ensembl=ENSCING00000001994.3|UniProtKB=F6XFP6 F6XFP6 PTHR22776:SF89 MARVEL-CONTAINING POTENTIAL LIPID RAFT-ASSOCIATED PROTEIN CKLF-LIKE MARVEL TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN 7 cellular anatomical entity#GO:0110165;membrane#GO:0016020 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000014454.2|UniProtKB=F6YAV6 F6YAV6 PTHR46297:SF1 ZINC FINGER CCCH-TYPE WITH G PATCH DOMAIN-CONTAINING PROTEIN ZINC FINGER CCCH-TYPE WITH G PATCH DOMAIN-CONTAINING PROTEIN cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription repressor activity#GO:0001217;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of biosynthetic process#GO:0009890;negative regulation of RNA metabolic process#GO:0051253;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000006814.3|UniProtKB=F6UMH6 F6UMH6 PTHR22883:SF23 ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN PALMITOYLTRANSFERASE ZDHHC6 palmitoyltransferase activity#GO:0016409;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular localization#GO:0051641;macromolecule localization#GO:0033036;macromolecule modification#GO:0043412;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;biosynthetic process#GO:0009058;establishment of protein localization#GO:0045184;establishment of protein localization to membrane#GO:0090150;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;protein palmitoylation#GO:0018345;protein metabolic process#GO:0019538;protein lipidation#GO:0006497;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;localization within membrane#GO:0051668;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein localization to membrane#GO:0072657;organonitrogen compound biosynthetic process#GO:1901566;protein targeting#GO:0006605;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;protein acylation#GO:0043543;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;lipoprotein biosynthetic process#GO:0042158;protein localization#GO:0008104;primary metabolic process#GO:0044238;localization#GO:0051179;protein targeting to membrane#GO:0006612;cellular macromolecule localization#GO:0070727;lipoprotein metabolic process#GO:0042157 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000022762.1|UniProtKB=H2Y0H4 H2Y0H4 LOC100186336 PTHR16557:SF2 ALKYLATED DNA REPAIR PROTEIN ALKB-RELATED NUCLEIC ACID DIOXYGENASE ALKBH1 ferrous iron binding#GO:0008198;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;transition metal ion binding#GO:0046914;catalytic activity, acting on a nucleic acid#GO:0140640;metal ion binding#GO:0046872;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity#GO:0016491;cation binding#GO:0043169;catalytic activity, acting on RNA#GO:0140098;demethylase activity#GO:0032451;iron ion binding#GO:0005506;dioxygenase activity#GO:0051213;catalytic activity, acting on DNA#GO:0140097;ion binding#GO:0043167 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;DNA modification#GO:0006304;macromolecule metabolic process#GO:0043170;RNA modification#GO:0009451;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;DNA demethylation#GO:0080111;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 DNA metabolism protein#PC00009 CIOIN|Ensembl=ENSCING00000014307.2|UniProtKB=F6UNF1 F6UNF1 PTHR15907:SF182 DUF614 FAMILY PROTEIN-RELATED PROTEIN PLANT CADMIUM RESISTANCE 1-RELATED CIOIN|Ensembl=ENSCING00000011428.2|UniProtKB=F7ADT2 F7ADT2 LOC100183844 PTHR13382:SF67 MITOCHONDRIAL ATP SYNTHASE COUPLING FACTOR B SCF E3 UBIQUITIN LIGASE COMPLEX F-BOX PROTEIN POF2 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ATP synthase#PC00002;primary active transporter#PC00068;transporter#PC00227 CIOIN|Ensembl=ENSCING00000006593.3|UniProtKB=F6QW33 F6QW33 PTHR11347:SF228 CYCLIC NUCLEOTIDE PHOSPHODIESTERASE HIGH AFFINITY CGMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 9A hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;cyclic-nucleotide phosphodiesterase activity#GO:0004112;phosphoric diester hydrolase activity#GO:0008081;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;cellular process#GO:0009987;cAMP-mediated signaling#GO:0019933;signaling#GO:0023052;cyclic-nucleotide-mediated signaling#GO:0019935 phosphodiesterase#PC00185 CIOIN|Ensembl=ENSCING00000024101.1|UniProtKB=A0A1W5BJ20 A0A1W5BJ20 PTHR12642:SF0 RIBOSOME BIOGENESIS PROTEIN NSA2 HOMOLOG RIBOSOME BIOGENESIS PROTEIN NSA2 HOMOLOG cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;ribosomal large subunit biogenesis#GO:0042273;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;maturation of 5.8S rRNA#GO:0000460;maturation of LSU-rRNA#GO:0000470;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;preribosome, large subunit precursor#GO:0030687;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;nuclear lumen#GO:0031981 CIOIN|Ensembl=ENSCING00000022628.1|UniProtKB=H2XPJ9 H2XPJ9 LOC100183994 PTHR10730:SF53 PROCOLLAGEN-LYSINE,2-OXOGLUTARATE 5-DIOXYGENASE/GLYCOSYLTRANSFERASE 25 FAMILY MEMBER GLYCOSYLTRANSFERASE 25 FAMILY MEMBER protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000014282.2|UniProtKB=F6VE25 F6VE25 PTHR24024:SF19 PULMONARY SURFACTANT-ASSOCIATED PROTEIN A FARMER, ISOFORM H extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 surfactant#PC00212;structural protein#PC00211 CIOIN|Ensembl=ENSCING00000005040.3|UniProtKB=F6SMQ3 F6SMQ3 PTHR24039:SF58 FIBRILLIN-RELATED EGF-LIKE DOMAIN-CONTAINING PROTEIN extracellular matrix structural protein#PC00103 CIOIN|Ensembl=ENSCING00000006139.3|UniProtKB=F6V3Q5 F6V3Q5 LOC100177266 PTHR47978:SF21 FAMILY NOT NAMED RAS-RELATED PROTEIN RAB-26 GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;anion binding#GO:0043168;ion binding#GO:0043167 regulation of biological process#GO:0050789;regulation of transport#GO:0051049;regulation of secretion#GO:0051046;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of localization#GO:0032879;regulation of secretion by cell#GO:1903530;regulation of vesicle-mediated transport#GO:0060627;regulation of exocytosis#GO:0017157 cytoplasm#GO:0005737;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 small GTPase#PC00208;G-protein#PC00020 CIOIN|Ensembl=ENSCING00000001993.3|UniProtKB=F6XFZ5 F6XFZ5 LOC100175516 PTHR44215:SF1 WD REPEAT-CONTAINING PROTEIN 75 WD REPEAT-CONTAINING PROTEIN 75 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of transcription by RNA polymerase I#GO:0045943;regulation of transcription by RNA polymerase I#GO:0006356;positive regulation of RNA biosynthetic process#GO:1902680;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of RNA biosynthetic process#GO:2001141;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of RNA metabolic process#GO:0051254;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000005031.3|UniProtKB=F6Z7S0 F6Z7S0 PTHR11458:SF0 DELTA-AMINOLEVULINIC ACID DEHYDRATASE DELTA-AMINOLEVULINIC ACID DEHYDRATASE cation binding#GO:0043169;carbon-oxygen lyase activity#GO:0016835;small molecule binding#GO:0036094;zinc ion binding#GO:0008270;hydro-lyase activity#GO:0016836;binding#GO:0005488;catalytic activity#GO:0003824;transition metal ion binding#GO:0046914;metal ion binding#GO:0046872;lyase activity#GO:0016829;ion binding#GO:0043167 tetrapyrrole metabolic process#GO:0033013;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;pigment metabolic process#GO:0042440;porphyrin-containing compound metabolic process#GO:0006778;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;heterocycle biosynthetic process#GO:0018130;heme biosynthetic process#GO:0006783;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;pigment biosynthetic process#GO:0046148;aromatic compound biosynthetic process#GO:0019438;organic substance metabolic process#GO:0071704;heme metabolic process#GO:0042168;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 dehydratase#PC00091;lyase#PC00144 Heme biosynthesis#P02746>porphobilinogen synthase#P02979 CIOIN|Ensembl=ENSCING00000005249.3|UniProtKB=F6V993 F6V993 PTHR24115:SF997 KINESIN-RELATED KINESIN-LIKE PROTEIN UNC-104 pyrophosphatase activity#GO:0016462;cytoskeletal protein binding#GO:0008092;microtubule motor activity#GO:0003777;tubulin binding#GO:0015631;ATP-dependent activity#GO:0140657;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;cytoskeletal motor activity#GO:0003774;microtubule binding#GO:0008017;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;ribonucleoside triphosphate phosphatase activity#GO:0017111;ATP hydrolysis activity#GO:0016887 microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;microtubule associated complex#GO:0005875;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 CIOIN|Ensembl=ENSCING00000006442.3|UniProtKB=Q4H372 Q4H372 Ci-MTA PTHR10865:SF29 METASTASIS-ASSOCIATED PROTEIN AND MESODERM INDUCTION EARLY RESPONSE PROTEIN METASTASIS ASSOCIATED 1-LIKE, ISOFORM D molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;histone deacetylase binding#GO:0042826;transcription corepressor activity#GO:0003714;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;transcription coactivator activity#GO:0003713;enzyme binding#GO:0019899;protein binding#GO:0005515 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of biosynthetic process#GO:0009890;negative regulation of RNA metabolic process#GO:0051253;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of biosynthetic process#GO:0009889;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-DNA complex#GO:0032993;catalytic complex#GO:1902494;chromatin#GO:0000785;nucleoplasm#GO:0005654;ATPase complex#GO:1904949;intracellular organelle lumen#GO:0070013;SWI/SNF superfamily-type complex#GO:0070603;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;histone deacetylase complex#GO:0000118;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116 p53 pathway#P00059>MTA2#P04615 CIOIN|Ensembl=ENSCING00000025006.1|UniProtKB=H2XVZ1 H2XVZ1 LOC100186645 PTHR10252:SF5 HISTONE-LIKE TRANSCRIPTION FACTOR CCAAT-RELATED DR1-ASSOCIATED COREPRESSOR sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;core promoter sequence-specific DNA binding#GO:0001046;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218 CIOIN|Ensembl=ENSCING00000007989.3|UniProtKB=F6W4Z8 F6W4Z8 LOC100182135 PTHR45961:SF6 IP21249P IP21249P Oxidative stress response#P00046>MKP5#P01131 CIOIN|Ensembl=ENSCING00000007168.3|UniProtKB=F6ZB59 F6ZB59 PTHR46745:SF1 TSC22 DOMAIN FAMILY PROTEIN 1 TSC22 DOMAIN FAMILY PROTEIN 1 regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of apoptotic process#GO:0042981;regulation of cell population proliferation#GO:0042127;negative regulation of programmed cell death#GO:0043069;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;positive regulation of cell population proliferation#GO:0008284;negative regulation of apoptotic process#GO:0043066;negative regulation of cellular process#GO:0048523;positive regulation of biological process#GO:0048518;regulation of programmed cell death#GO:0043067;positive regulation of cellular process#GO:0048522 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000021041.1|UniProtKB=H2XNY0 H2XNY0 PTHR19957:SF83 SYNTAXIN SYNTAXIN-16 molecular adaptor activity#GO:0060090;protein binding#GO:0005515;SNAP receptor activity#GO:0005484;binding#GO:0005488;SNARE binding#GO:0000149;protein-macromolecule adaptor activity#GO:0030674 vesicle fusion#GO:0006906;cellular localization#GO:0051641;organelle localization#GO:0051640;macromolecule localization#GO:0033036;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;membrane fusion#GO:0061025;establishment of localization#GO:0051234;organelle organization#GO:0006996;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;vesicle organization#GO:0016050;intracellular transport#GO:0046907;organelle fusion#GO:0048284 cytoplasm#GO:0005737;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;SNARE complex#GO:0031201;cellular anatomical entity#GO:0110165;membrane#GO:0016020;intracellular anatomical structure#GO:0005622 SNARE protein#PC00034;membrane traffic protein#PC00150 Nicotinic acetylcholine receptor signaling pathway#P00044>SNARE Complex#P01091;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>SNARE Complex#P01079 CIOIN|Ensembl=ENSCING00000008254.3|UniProtKB=Q1RL96 Q1RL96 Ci-ZF(C2H2)-129 PTHR12958:SF3 FRIEND OF GATA2-RELATED ZINC FINGER PROTEIN USH positive regulation of nitrogen compound metabolic process#GO:0051173;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;heart development#GO:0007507;positive regulation of RNA biosynthetic process#GO:1902680;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;animal organ development#GO:0048513;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;positive regulation of biological process#GO:0048518;negative regulation of cellular process#GO:0048523;cellular developmental process#GO:0048869;circulatory system development#GO:0072359;negative regulation of biosynthetic process#GO:0009890;regulation of DNA-templated transcription#GO:0006355;multicellular organism development#GO:0007275;negative regulation of metabolic process#GO:0009892;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;negative regulation of nitrogen compound metabolic process#GO:0051172;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;positive regulation of RNA metabolic process#GO:0051254;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 gene-specific transcriptional regulator#PC00264;transcription cofactor#PC00217 CIOIN|Ensembl=ENSCING00000007599.3|UniProtKB=H2XR58 H2XR58 PTHR10695:SF46 DEPHOSPHO-COA KINASE-RELATED BIFUNCTIONAL COENZYME A SYNTHASE-RELATED transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301 cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 kinase#PC00137 Coenzyme A biosynthesis#P02736>Pantetheine-phosphate adenyltransferase#P02886;Coenzyme A biosynthesis#P02736>Dephospho-CoA kinase#P02884 CIOIN|Ensembl=ENSCING00000003672.3|UniProtKB=F7AD85 F7AD85 PTHR11475:SF4 OXIDASE/PEROXIDASE CHORION PEROXIDASE oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;antioxidant activity#GO:0016209;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 peroxidase#PC00180;metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000013647.2|UniProtKB=F6UBW4 F6UBW4 PTHR36978:SF4 P-LOOP CONTAINING NUCLEOTIDE TRIPHOSPHATE HYDROLASE P-LOOP CONTAINING NUCLEOSIDE TRIPHOSPHATE HYDROLASE PROTEIN metabolite interconversion enzyme#PC00262;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000019428.1|UniProtKB=H2XSM7 H2XSM7 LOC101242180 PTHR10924:SF4 MAJOR FACILITATOR SUPERFAMILY PROTEIN-RELATED GH15861P tetrapyrrole binding#GO:0046906;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;binding#GO:0005488;organic cyclic compound binding#GO:0097159;heme binding#GO:0020037 localization#GO:0051179;organic substance transport#GO:0071702;metal ion transport#GO:0030001;establishment of localization#GO:0051234;transport#GO:0006810;monoatomic cation transport#GO:0006812;nitrogen compound transport#GO:0071705;iron ion transport#GO:0006826;transition metal ion transport#GO:0000041;monoatomic ion transport#GO:0006811 cellular anatomical entity#GO:0110165;membrane#GO:0016020 secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000002596.3|UniProtKB=F7B363 F7B363 PTHR11475:SF144 OXIDASE/PEROXIDASE NAD(P)H OXIDASE (H2O2-FORMING) oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;antioxidant activity#GO:0016209;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 peroxidase#PC00180;metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000009302.3|UniProtKB=F7A6I3 F7A6I3 PTHR11486:SF140 FIBROBLAST GROWTH FACTOR EGL-17 molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;binding#GO:0005488;growth factor activity#GO:0008083;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;growth factor receptor binding#GO:0070851;protein binding#GO:0005515;signaling receptor binding#GO:0005102;fibroblast growth factor receptor binding#GO:0005104 positive regulation of gene expression#GO:0010628;regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;positive regulation of cell population proliferation#GO:0008284;positive regulation of protein modification process#GO:0031401;regulation of intracellular signal transduction#GO:1902531;response to fibroblast growth factor#GO:0071774;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;regulation of cell migration#GO:0030334;anatomical structure morphogenesis#GO:0009653;regulation of signal transduction#GO:0009966;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;cellular developmental process#GO:0048869;cellular response to endogenous stimulus#GO:0071495;positive regulation of phosphorus metabolic process#GO:0010562;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;positive regulation of cell communication#GO:0010647;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;fibroblast growth factor receptor signaling pathway#GO:0008543;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;regulation of locomotion#GO:0040012;response to growth factor#GO:0070848;animal organ development#GO:0048513;regulation of signaling#GO:0023051;developmental process#GO:0032502;positive regulation of MAPK cascade#GO:0043410;positive regulation of response to stimulus#GO:0048584;positive regulation of biosynthetic process#GO:0009891;cell differentiation#GO:0030154;response to endogenous stimulus#GO:0009719;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of intracellular signal transduction#GO:1902533;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;signaling#GO:0023052;regulation of cell communication#GO:0010646;positive regulation of protein phosphorylation#GO:0001934;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;regulation of cell population proliferation#GO:0042127;regulation of cell motility#GO:2000145;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;cellular response to growth factor stimulus#GO:0071363;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;animal organ morphogenesis#GO:0009887;cellular response to fibroblast growth factor stimulus#GO:0044344 cytoplasm#GO:0005737;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576;intracellular anatomical structure#GO:0005622 intercellular signal molecule#PC00207;growth factor#PC00112 CIOIN|Ensembl=ENSCING00000017600.2|UniProtKB=F6VVB7 F6VVB7 PTHR10177:SF344 CYCLINS G1_S-SPECIFIC CYCLIN-E protein kinase regulator activity#GO:0019887;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;enzyme regulator activity#GO:0030234 regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;mitotic cell cycle phase transition#GO:0044772;regulation of nitrogen compound metabolic process#GO:0051171;cell cycle G1/S phase transition#GO:0044843;cell cycle process#GO:0022402;positive regulation of cell cycle#GO:0045787;positive regulation of cell cycle G1/S phase transition#GO:1902808;regulation of catalytic activity#GO:0050790;mitotic cell cycle process#GO:1903047;G1/S transition of mitotic cell cycle#GO:0000082;regulation of phosphorus metabolic process#GO:0051174;regulation of biological process#GO:0050789;mitotic cell cycle#GO:0000278;regulation of molecular function#GO:0065009;positive regulation of cell cycle process#GO:0090068;positive regulation of mitotic cell cycle#GO:0045931;regulation of protein serine/threonine kinase activity#GO:0071900;regulation of G1/S transition of mitotic cell cycle#GO:2000045;positive regulation of biological process#GO:0048518;regulation of cyclin-dependent protein serine/threonine kinase activity#GO:0000079;regulation of kinase activity#GO:0043549;regulation of protein kinase activity#GO:0045859;regulation of mitotic cell cycle phase transition#GO:1901990;regulation of cell cycle phase transition#GO:1901987;cellular process#GO:0009987;cell cycle phase transition#GO:0044770;regulation of cell cycle process#GO:0010564;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of macromolecule metabolic process#GO:0060255;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;regulation of phosphorylation#GO:0042325;regulation of mitotic cell cycle#GO:0007346;regulation of transferase activity#GO:0051338;regulation of cell cycle G1/S phase transition#GO:1902806;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 microtubule organizing center#GO:0005815;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;serine/threonine protein kinase complex#GO:1902554;protein kinase complex#GO:1902911;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856 kinase activator#PC00138 Cell cycle#P00013>CdkC#P00489;p53 pathway#P00059>Cyclin E#P04610;p53 pathway feedback loops 2#P04398>cyclin E#P04664;Cell cycle#P00013>Cyclin E#P00483 CIOIN|Ensembl=ENSCING00000006849.3|UniProtKB=F7AFK4 F7AFK4 PTHR11309:SF126 FRIZZLED FRIZZLED-2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;protein binding#GO:0005515;Wnt-protein binding#GO:0017147;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;non-canonical Wnt signaling pathway#GO:0035567;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;cell-cell signaling by wnt#GO:0198738;canonical Wnt signaling pathway#GO:0060070;cell-cell signaling#GO:0007267;signaling#GO:0023052;Wnt signaling pathway#GO:0016055 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Wnt signaling pathway#P00057>Frizzled#P01428;Cadherin signaling pathway#P00012>Frizzled#P00475;Alzheimer disease-presenilin pathway#P00004>Frizzled#P00119 CIOIN|Ensembl=ENSCING00000010157.3|UniProtKB=H2XU50 H2XU50 LOC100175001 PTHR21245:SF2 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN RNA-BINDING PROTEIN 18-RELATED nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000006987.3|UniProtKB=F6SY72 F6SY72 PTHR11829:SF206 FORKHEAD BOX PROTEIN FORKHEAD BOX PROTEIN Q1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;anatomical structure morphogenesis#GO:0009653;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 CIOIN|Ensembl=ENSCING00000006841.3|UniProtKB=F7AFY1 F7AFY1 PTHR11616:SF289 SODIUM/CHLORIDE DEPENDENT TRANSPORTER TRANSPORTER secondary active monocarboxylate transmembrane transporter activity#GO:0015355;inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;organic acid:sodium symporter activity#GO:0005343;organic acid transmembrane transporter activity#GO:0005342;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;chloride transmembrane transporter activity#GO:0015108;organic anion transmembrane transporter activity#GO:0008514;monoatomic cation transmembrane transporter activity#GO:0008324;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;amino acid:sodium symporter activity#GO:0005283;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;metal ion transmembrane transporter activity#GO:0046873;active monoatomic ion transmembrane transporter activity#GO:0022853;monoatomic anion transmembrane transporter activity#GO:0008509;monocarboxylic acid transmembrane transporter activity#GO:0008028;amino acid transmembrane transporter activity#GO:0015171;inorganic anion transmembrane transporter activity#GO:0015103;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;organic anion transport#GO:0015711;amino acid transport#GO:0006865;organic acid transport#GO:0015849;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;localization#GO:0051179;organic substance transport#GO:0071702;sodium ion transport#GO:0006814;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;sodium ion transmembrane transport#GO:0035725 cell projection#GO:0042995;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 primary active transporter#PC00068;transporter#PC00227 CIOIN|Ensembl=ENSCING00000001646.3|UniProtKB=F6YIY8 F6YIY8 LOC100182572 PTHR12821:SF0 BYSTIN BYSTIN snoRNA binding#GO:0030515;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;preribosome, small subunit precursor#GO:0030688;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;nuclear lumen#GO:0031981 CIOIN|Ensembl=ENSCING00000008827.3|UniProtKB=F7BIS1 F7BIS1 PTHR10048:SF22 PHOSPHATIDYLINOSITOL KINASE PHOSPHATIDYLINOSITOL 4-KINASE BETA transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301;lipid kinase activity#GO:0001727 lipid metabolic process#GO:0006629;signal transduction#GO:0007165;phospholipid biosynthetic process#GO:0008654;organophosphate biosynthetic process#GO:0090407;phosphatidylinositol biosynthetic process#GO:0006661;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;lipid biosynthetic process#GO:0008610;phosphatidylinositol phosphate biosynthetic process#GO:0046854;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;glycerolipid metabolic process#GO:0046486;intracellular signal transduction#GO:0035556;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;glycerolipid biosynthetic process#GO:0045017;cellular metabolic process#GO:0044237;cell communication#GO:0007154;glycerophospholipid metabolic process#GO:0006650;phosphatidylinositol metabolic process#GO:0046488;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;glycerophospholipid biosynthetic process#GO:0046474;biological regulation#GO:0065007;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;membrane#GO:0016020;intracellular anatomical structure#GO:0005622 kinase#PC00137 CIOIN|Ensembl=ENSCING00000020010.1|UniProtKB=F6QQ72 F6QQ72 PTHR11474:SF126 TYROSINASE FAMILY MEMBER TYROSINASE-LIKE PROTEIN TYR-1-RELATED oxygenase#PC00177;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000018514.1|UniProtKB=H2XSU1 H2XSU1 PTHR11599:SF59 PROTEASOME SUBUNIT ALPHA/BETA PROTEASOME SUBUNIT BETA TYPE-1 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;peptidase complex#GO:1905368;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;proteasome complex#GO:0000502;membrane-bounded organelle#GO:0043227;endopeptidase complex#GO:1905369;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protease#PC00190;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000012519.2|UniProtKB=F7BDQ8 F7BDQ8 PTHR15665:SF1 ASTEROID PROTEIN PROTEIN ASTEROID HOMOLOG 1 CIOIN|Ensembl=ENSCING00000001609.3|UniProtKB=F6RZL7 F6RZL7 LOC100175433 PTHR16296:SF2 UNCHARACTERIZED HYPOTHALAMUS PROTEIN HT007 TRANSMEMBRANE PROTEIN 126A cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrial respiratory chain complex I assembly#GO:0032981;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;mitochondrion organization#GO:0007005;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000003426.3|UniProtKB=F6XLK3 F6XLK3 LOC100174998 PTHR43128:SF16 L-2-HYDROXYCARBOXYLATE DEHYDROGENASE (NAD(P)(+)) L-LACTATE DEHYDROGENASE oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 organic hydroxy compound metabolic process#GO:1901615;oxoacid metabolic process#GO:0043436;cellular metabolic process#GO:0044237;cellular process#GO:0009987;carboxylic acid metabolic process#GO:0019752;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000020168.1|UniProtKB=H2Y1J7 H2Y1J7 PTHR23238:SF31 RNA BINDING PROTEIN GH13594P-RELATED molecular adaptor activity#GO:0060090;transcription regulator activity#GO:0140110;nucleic acid binding#GO:0003676;transcription coregulator activity#GO:0003712;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159;protein-macromolecule adaptor activity#GO:0030674 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000009912.3|UniProtKB=F6RAE2 F6RAE2 PTHR24637:SF420 COLLAGEN NEMATODE CUTICLE COLLAGEN N-TERMINAL DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000008673.3|UniProtKB=F6ZF50 F6ZF50 LOC100183439 PTHR24068:SF33 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2Q 2 ISOFORM 1 ubiquitin-like protein conjugating enzyme activity#GO:0061650;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin conjugating enzyme activity#GO:0061631;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein polyubiquitination#GO:0000209;post-translational protein modification#GO:0043687;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000025068.1|UniProtKB=Q256Z9 Q256Z9 b3galt6 PTHR11214:SF3 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE BETA-1,3-GALACTOSYLTRANSFERASE 6 transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824 cytoplasm#GO:0005737;bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;Golgi membrane#GO:0000139;membrane#GO:0016020;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111 CIOIN|Ensembl=ENSCING00000012553.2|UniProtKB=F7AB05 F7AB05 LOC100184431 PTHR14845:SF0 COILED-COIL DOMAIN-CONTAINING 166 DUF4515 DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000005560.3|UniProtKB=F6USX3 F6USX3 PTHR10887:SF433 DNA2/NAM7 HELICASE FAMILY DNA REPLICATION ATP-DEPENDENT HELICASE_NUCLEASE DNA2 hydrolase activity, acting on ester bonds#GO:0016788;DNA endonuclease activity#GO:0004520;nuclease activity#GO:0004518;catalytic activity#GO:0003824;endonuclease activity#GO:0004519;hydrolase activity#GO:0016787;catalytic activity, acting on a nucleic acid#GO:0140640;DNA nuclease activity#GO:0004536;catalytic activity, acting on DNA#GO:0140097 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;DNA-templated DNA replication#GO:0006261;replication fork processing#GO:0031297;DNA replication#GO:0006260;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 RNA helicase#PC00032 DNA replication#P00017>Hel#P00532 CIOIN|Ensembl=ENSCING00000007963.3|UniProtKB=F6Z833 F6Z833 PTHR10868:SF1 SIGMA 1-TYPE OPIOID RECEPTOR-RELATED SIGMA NON-OPIOID INTRACELLULAR RECEPTOR 1 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transmembrane signal receptor#PC00197 CIOIN|Ensembl=ENSCING00000001873.2|UniProtKB=F6T6D5 F6T6D5 LOC100185973 PTHR22802:SF379 C-TYPE LECTIN SUPERFAMILY MEMBER CHONDROITIN SULFATE PROTEOGLYCAN 2 ISOFORM X1 membrane traffic protein#PC00150 CIOIN|Ensembl=ENSCING00000020812.1|UniProtKB=H2XRS3 H2XRS3 LOC100180269 PTHR23183:SF0 NOP14 NUCLEOLAR PROTEIN 14 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;maturation of SSU-rRNA#GO:0030490;ribosomal small subunit biogenesis#GO:0042274;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;small-subunit processome#GO:0032040;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;preribosome, small subunit precursor#GO:0030688;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;nuclear lumen#GO:0031981;90S preribosome#GO:0030686;nuclear protein-containing complex#GO:0140513 RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000023294.1|UniProtKB=H2XRK4 H2XRK4 PTHR10751:SF29 GUANYLATE BINDING PROTEIN ATLASTIN GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;ion binding#GO:0043167;anion binding#GO:0043168 heterotrimeric G-protein#PC00117;G-protein#PC00020 CIOIN|Ensembl=ENSCING00000007953.3|UniProtKB=F6Z8E9 F6Z8E9 LOC100182982 PTHR12812:SF0 HEPARAN SULFATE 6-O-SULFOTRANSFERASE 3 HEPARAN-SULFATE 6-O-SULFOTRANSFERASE sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824 glycoprotein biosynthetic process#GO:0009101;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;sulfur compound metabolic process#GO:0006790;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;proteoglycan metabolic process#GO:0006029;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;proteoglycan biosynthetic process#GO:0030166;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000019126.1|UniProtKB=H2XXT4 H2XXT4 PTHR10334:SF591 CYSTEINE-RICH SECRETORY PROTEIN-RELATED GLIOMA PATHOGENESIS-RELATED PROTEIN 1-LIKE extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 defense/immunity protein#PC00090 CIOIN|Ensembl=ENSCING00000011809.2|UniProtKB=F6S021 F6S021 PTHR43248:SF3 2-SUCCINYL-6-HYDROXY-2,4-CYCLOHEXADIENE-1-CARBOXYLATE SYNTHASE AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN metabolite interconversion enzyme#PC00262;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000007337.3|UniProtKB=F6XYT3 F6XYT3 PTHR43243:SF4 INNER MEMBRANE TRANSPORTER YGJI-RELATED CATIONIC AMINO ACID TRANSPORTER 4 transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;amino acid transmembrane transporter activity#GO:0015171;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215;organic acid transmembrane transporter activity#GO:0005342 localization#GO:0051179;organic substance transport#GO:0071702;establishment of localization#GO:0051234;amino acid transport#GO:0006865;organic anion transport#GO:0015711;organic acid transport#GO:0015849;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942 amino acid transporter#PC00046;transporter#PC00227 CIOIN|Ensembl=ENSCING00000023987.1|UniProtKB=H2XMY1 H2XMY1 LOC100180457 PTHR12465:SF0 UBIQUITIN SPECIFIC PROTEASE HOMOLOG 49 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 20 transcription coactivator activity#GO:0003713;molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;protein-macromolecule adaptor activity#GO:0030674 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;mediator complex#GO:0016592;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000004012.3|UniProtKB=F6VXL3 F6VXL3 LOC100187076 PTHR13710:SF105 DNA HELICASE RECQ FAMILY MEMBER ATP-DEPENDENT DNA HELICASE Q1 ATP-dependent activity, acting on DNA#GO:0008094;3'-5' DNA helicase activity#GO:0043138;helicase activity#GO:0004386;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;DNA helicase activity#GO:0003678;catalytic activity, acting on DNA#GO:0140097 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;DNA geometric change#GO:0032392;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;DNA conformation change#GO:0071103;nucleic acid metabolic process#GO:0090304;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;response to stress#GO:0006950;organelle organization#GO:0006996;chromosome organization#GO:0051276;nitrogen compound metabolic process#GO:0006807;DNA duplex unwinding#GO:0032508;cellular response to stress#GO:0033554;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259;metabolic process#GO:0008152 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;chromosome#GO:0005694;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA helicase#PC00011;DNA metabolism protein#PC00009 CIOIN|Ensembl=ENSCING00000005810.3|UniProtKB=F6RGF8 F6RGF8 PTHR13793:SF150 PHD FINGER PROTEINS PHD FINGER PROTEIN 14 regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 zinc finger transcription factor#PC00244 CIOIN|Ensembl=ENSCING00000009619.3|UniProtKB=F7ACM5 F7ACM5 LOC100182343 PTHR11618:SF13 TRANSCRIPTION INITIATION FACTOR IIB-RELATED TRANSCRIPTION INITIATION FACTOR IIB cellular aromatic compound metabolic process#GO:0006725;DNA-templated transcription#GO:0006351;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;gene expression#GO:0010467;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;DNA-templated transcription initiation#GO:0006352;aromatic compound biosynthetic process#GO:0019438;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 protein-containing complex#GO:0032991;protein-DNA complex#GO:0032993 general transcription factor#PC00259 Transcription regulation by bZIP transcription factor#P00055>TFIIB#P01397;General transcription regulation#P00023>TFIIB#P00668 CIOIN|Ensembl=ENSCING00000009517.3|UniProtKB=F6WWY7 F6WWY7 PTHR21345:SF3 SPIRE PROTEIN SPIRE cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;cell division#GO:0051301;organelle localization#GO:0051640;membrane organization#GO:0061024;cellular process involved in reproduction in multicellular organism#GO:0022412;nuclear division#GO:0000280;transport#GO:0006810;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;protein-containing complex assembly#GO:0065003;actin filament polymerization#GO:0030041;cytokinetic process#GO:0032506;actin filament-based process#GO:0030029;membrane invagination#GO:0010324;establishment of localization#GO:0051234;meiotic cell cycle process#GO:1903046;supramolecular fiber organization#GO:0097435;cytoskeleton-dependent cytokinesis#GO:0061640;actin filament organization#GO:0007015;reproductive process#GO:0022414;cytoskeleton organization#GO:0007010;establishment of organelle localization#GO:0051656;cytokinesis#GO:0000910;spindle localization#GO:0051653;multicellular organismal reproductive process#GO:0048609;cellular component assembly#GO:0022607;gamete generation#GO:0007276;multicellular organism reproduction#GO:0032504;meiotic cell cycle#GO:0051321;vesicle-mediated transport#GO:0016192;actin polymerization or depolymerization#GO:0008154;cellular component organization#GO:0016043;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;establishment of spindle localization#GO:0051293;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;reproduction#GO:0000003;microtubule-based process#GO:0007017;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;meiotic nuclear division#GO:0140013;sexual reproduction#GO:0019953;protein polymerization#GO:0051258;cell cycle#GO:0007049;multicellular organismal process#GO:0032501;establishment of localization in cell#GO:0051649;organelle fission#GO:0048285;intracellular transport#GO:0046907;actin cytoskeleton organization#GO:0030036 intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;organelle membrane#GO:0031090;cell periphery#GO:0071944;cell cortex#GO:0005938;cellular anatomical entity#GO:0110165;vesicle membrane#GO:0012506;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cytoplasmic vesicle membrane#GO:0030659 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 CIOIN|Ensembl=ENSCING00000002604.3|UniProtKB=F6TQR9 F6TQR9 LOC113474070 PTHR12001:SF55 GERANYLGERANYL PYROPHOSPHATE SYNTHASE ALL TRANS-POLYPRENYL-DIPHOSPHATE SYNTHASE PDSS2 prenyltransferase activity#GO:0004659;transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;cellular process#GO:0009987;isoprenoid metabolic process#GO:0006720;primary metabolic process#GO:0044238;isoprenoid biosynthetic process#GO:0008299;ubiquinone biosynthetic process#GO:0006744;small molecule biosynthetic process#GO:0044283;cellular lipid metabolic process#GO:0044255;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000013133.2|UniProtKB=F6ZH72 F6ZH72 LOC100175439 PTHR13255:SF0 ATAXIN-10 ATAXIN-10 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000019260.1|UniProtKB=F6YR02 F6YR02 PTHR18866:SF33 CARBOXYLASE:PYRUVATE/ACETYL-COA/PROPIONYL-COA CARBOXYLASE METHYLCROTONOYL-COA CARBOXYLASE SUBUNIT ALPHA, MITOCHONDRIAL-RELATED ligase#PC00142 Methylmalonyl pathway#P02755>Propionyl-CoA carboxylase#P03033 CIOIN|Ensembl=ENSCING00000021693.1|UniProtKB=H2XTV5 H2XTV5 PTHR24104:SF47 E3 UBIQUITIN-PROTEIN LIGASE NHLRC1-RELATED E3 UBIQUITIN-PROTEIN LIGASE NHLRC1 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein polyubiquitination#GO:0000209;proteasomal protein catabolic process#GO:0010498;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000003348.3|UniProtKB=F7BMH5 F7BMH5 PTHR23322:SF6 FAS-ASSOCIATED PROTEIN UBX DOMAIN-CONTAINING PROTEIN 7 protein binding#GO:0005515;ubiquitin-like protein binding#GO:0032182;binding#GO:0005488;ubiquitin binding#GO:0043130 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000011683.2|UniProtKB=F6SSW4 F6SSW4 LOC100178841 PTHR11712:SF336 POLYKETIDE SYNTHASE-RELATED 3-OXOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE, MITOCHONDRIAL transferase activity#GO:0016740;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity#GO:0003824 organic acid biosynthetic process#GO:0016053;lipid metabolic process#GO:0006629;oxoacid metabolic process#GO:0043436;monocarboxylic acid biosynthetic process#GO:0072330;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;fatty acid metabolic process#GO:0006631;small molecule biosynthetic process#GO:0044283;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;fatty acid biosynthetic process#GO:0006633;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 CIOIN|Ensembl=ENSCING00000002022.3|UniProtKB=F6W6I5 F6W6I5 PTHR24347:SF412 SERINE/THREONINE-PROTEIN KINASE SERINE_THREONINE-PROTEIN KINASE H1 HOMOLOG-RELATED non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CaMK#P00847;Ionotropic glutamate receptor pathway#P00037>CaMKII#P01023 CIOIN|Ensembl=ENSCING00000007356.3|UniProtKB=F6VTM3 F6VTM3 PTHR10972:SF200 OXYSTEROL-BINDING PROTEIN-RELATED OXYSTEROL-BINDING PROTEIN-RELATED PROTEIN 9 binding#GO:0005488;organic cyclic compound binding#GO:0097159;sterol transporter activity#GO:0015248;steroid binding#GO:0005496;sterol binding#GO:0032934;lipid binding#GO:0008289;lipid transporter activity#GO:0005319;transporter activity#GO:0005215 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;membrane#GO:0016020;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transfer/carrier protein#PC00219 CIOIN|Ensembl=ENSCING00000009192.3|UniProtKB=F6YLX3 F6YLX3 PTHR15603:SF4 SH3 DOMAIN-CONTAINING PROTEIN SH3 DOMAIN-BINDING PROTEIN 4-LIKE cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000017480.2|UniProtKB=F6VLY9 F6VLY9 PTHR20920:SF5 RPE-SPONDIN SMB DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000007876.3|UniProtKB=F6TGX2 F6TGX2 PTHR11259:SF1 RAS-RELATED GTP BINDING RAG/GTR YEAST RAS-RELATED GTP-BINDING PROTEIN GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of catabolic process#GO:0009894;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;response to extracellular stimulus#GO:0009991;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;cellular response to starvation#GO:0009267;positive regulation of TOR signaling#GO:0032008;regulation of signal transduction#GO:0009966;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;negative regulation of cellular process#GO:0048523;cellular response to extracellular stimulus#GO:0031668;regulation of cell communication#GO:0010646;positive regulation of TORC1 signaling#GO:1904263;cellular response to stimulus#GO:0051716;regulation of TORC1 signaling#GO:1903432;regulation of autophagy#GO:0010506;negative regulation of cellular catabolic process#GO:0031330;negative regulation of metabolic process#GO:0009892;cell communication#GO:0007154;response to nutrient levels#GO:0031667;regulation of cellular catabolic process#GO:0031329;negative regulation of autophagy#GO:0010507;cellular process#GO:0009987;regulation of TOR signaling#GO:0032006;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;response to stress#GO:0006950;negative regulation of catabolic process#GO:0009895;regulation of cellular process#GO:0050794;cellular response to nutrient levels#GO:0031669;response to starvation#GO:0042594;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;cellular response to external stimulus#GO:0071496;cellular response to stress#GO:0033554;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;lysosome#GO:0005764;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;lytic vacuole#GO:0000323;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 small GTPase#PC00208;G-protein#PC00020 CIOIN|Ensembl=ENSCING00000012739.2|UniProtKB=F7A9D2 F7A9D2 PTHR46252:SF3 BRORIN FAMILY MEMBER KIELIN_CHORDIN-LIKE PROTEIN regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;negative regulation of response to stimulus#GO:0048585;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;regulation of BMP signaling pathway#GO:0030510;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;negative regulation of BMP signaling pathway#GO:0030514;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cellular response to growth factor stimulus#GO:0090287;negative regulation of signal transduction#GO:0009968;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648 receptor complex#GO:0043235;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;plasma membrane signaling receptor complex#GO:0098802;monoatomic ion channel complex#GO:0034702;extracellular region#GO:0005576;transporter complex#GO:1990351;plasma membrane protein complex#GO:0098797;transmembrane transporter complex#GO:1902495;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 CIOIN|Ensembl=ENSCING00000008838.3|UniProtKB=F7B0A7 F7B0A7 PTHR11547:SF57 ARGININE OR CREATINE KINASE PHOSPHAGEN KINASE C-TERMINAL DOMAIN-CONTAINING PROTEIN transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301 organophosphate biosynthetic process#GO:0090407;nitrogen compound metabolic process#GO:0006807;cellular modified amino acid metabolic process#GO:0006575;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;organophosphate metabolic process#GO:0019637;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;metabolic process#GO:0008152;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 amino acid kinase#PC00045 CIOIN|Ensembl=ENSCING00000016481.2|UniProtKB=F6YN96 F6YN96 PTHR13620:SF104 3-5 EXONUCLEASE EXONUCLEASE 3'-5' DOMAIN-CONTAINING PROTEIN 2 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;3'-5' exonuclease activity#GO:0008408;exonuclease activity#GO:0004527;catalytic activity#GO:0003824 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000007756.3|UniProtKB=F6XTY4 F6XTY4 LOC100178569 PTHR47958:SF31 ATP-DEPENDENT RNA HELICASE DBP3 RNA HELICASE catalytic activity, acting on RNA#GO:0140098;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;helicase activity#GO:0004386;ATP-dependent activity#GO:0140657;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;catalytic activity, acting on a nucleic acid#GO:0140640;mRNA binding#GO:0003729 poly(A)+ mRNA export from nucleus#GO:0016973;mRNA export from nucleus#GO:0006406;cellular localization#GO:0051641;macromolecule biosynthetic process#GO:0009059;macromolecule localization#GO:0033036;establishment of RNA localization#GO:0051236;macromolecule metabolic process#GO:0043170;transport#GO:0006810;nucleic acid transport#GO:0050657;nitrogen compound transport#GO:0071705;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;mRNA transport#GO:0051028;RNA localization#GO:0006403;localization#GO:0051179;organic substance transport#GO:0071702;nuclear export#GO:0051168;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;RNA transport#GO:0050658;nucleobase-containing compound transport#GO:0015931;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;nuclear transport#GO:0051169;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytoplasmic stress granule#GO:0010494;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464;intracellular anatomical structure#GO:0005622 RNA helicase#PC00032 CIOIN|Ensembl=ENSCING00000000064.3|UniProtKB=F6V725 F6V725 PTHR14063:SF1 PROTEIN LIN-7 HOMOLOG PDZ DOMAIN-CONTAINING PROTEIN 11 establishment or maintenance of cell polarity#GO:0007163;cellular localization#GO:0051641;establishment or maintenance of epithelial cell apical/basal polarity#GO:0045197;macromolecule localization#GO:0033036;transport#GO:0006810;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;secretion#GO:0046903;neurotransmitter transport#GO:0006836;synaptic signaling#GO:0099536;signal release#GO:0023061;establishment or maintenance of apical/basal cell polarity#GO:0035088;cell-cell signaling#GO:0007267;signaling#GO:0023052;secretion by cell#GO:0032940;neurotransmitter secretion#GO:0007269;localization within membrane#GO:0051668;protein localization to membrane#GO:0072657;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;protein localization#GO:0008104;protein localization to cell periphery#GO:1990778;localization#GO:0051179;cellular macromolecule localization#GO:0070727;signal release from synapse#GO:0099643;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;establishment or maintenance of bipolar cell polarity#GO:0061245;export from cell#GO:0140352 basal plasma membrane#GO:0009925;synapse#GO:0045202;anchoring junction#GO:0070161;cell-cell junction#GO:0005911;basolateral plasma membrane#GO:0016323;cell junction#GO:0030054;plasma membrane region#GO:0098590;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;basal part of cell#GO:0045178;membrane#GO:0016020;plasma membrane#GO:0005886 cell junction protein#PC00070 CIOIN|Ensembl=ENSCING00000011971.2|UniProtKB=F6SK91 F6SK91 LOC113474072 PTHR10344:SF1 THYMIDYLATE KINASE THYMIDYLATE KINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;phosphotransferase activity, phosphate group as acceptor#GO:0016776 cellular aromatic compound metabolic process#GO:0006725;nucleoside triphosphate metabolic process#GO:0009141;pyrimidine nucleotide metabolic process#GO:0006220;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;pyrimidine-containing compound metabolic process#GO:0072527;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;nucleoside diphosphate metabolic process#GO:0009132;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;nucleoside triphosphate biosynthetic process#GO:0009142;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 nucleotide kinase#PC00172 De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>dTMP kinase#P02916 CIOIN|Ensembl=ENSCING00000014032.2|UniProtKB=F6RGU6 F6RGU6 LOC100177426 PTHR45692:SF1 G_PROTEIN_RECEP_F2_4 DOMAIN-CONTAINING PROTEIN G-PROTEIN COUPLED RECEPTORS FAMILY 2 PROFILE 2 DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000011866.1|UniProtKB=F6Z2B7 F6Z2B7 PTHR34221:SF1 HYPOTHETICAL PROTEIN LOC691189 SUBFAMILY NOT NAMED CIOIN|Ensembl=ENSCING00000012189.2|UniProtKB=F6TU49 F6TU49 PTHR11049:SF16 ACYL COENZYME A THIOESTER HYDROLASE PROTEIN VDLD hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;fatty acyl-CoA hydrolase activity#GO:0047617;catalytic activity#GO:0003824;thiolester hydrolase activity#GO:0016790 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;acyl-CoA metabolic process#GO:0006637;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;amide metabolic process#GO:0043603;purine nucleotide metabolic process#GO:0006163;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;nucleobase-containing small molecule metabolic process#GO:0055086 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 esterase#PC00097 CIOIN|Ensembl=ENSCING00000002533.3|UniProtKB=F6VVK4 F6VVK4 zf(ring)-24 PTHR10044:SF139 INHIBITOR OF APOPTOSIS DEATH-ASSOCIATED INHIBITOR OF APOPTOSIS 2 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protease inhibitor#PC00191 CIOIN|Ensembl=ENSCING00000002706.3|UniProtKB=F6UDW5 F6UDW5 PTHR47167:SF4 SERINE/THREONINE-PROTEIN KINASE TAO1-LIKE PROTEIN SERINE_THREONINE-PROTEIN KINASE TAO transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;phosphorylation#GO:0016310;protein phosphorylation#GO:0006468;cellular process#GO:0009987;protein metabolic process#GO:0019538;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000001299.3|UniProtKB=F6WWK0 F6WWK0 PTHR19846:SF0 WD40 REPEAT PROTEIN PRE-MRNA PROCESSING FACTOR 4 RNA splicing factor#PC00148;RNA metabolism protein#PC00031;RNA processing factor#PC00147 mRNA splicing#P00058>U4#P01476;mRNA splicing#P00058>U6#P01473 CIOIN|Ensembl=ENSCING00000024701.1|UniProtKB=H2XPA7 H2XPA7 LOC100184518 PTHR43691:SF11 URIDINE PHOSPHORYLASE FI09636P-RELATED cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 nucleotide kinase#PC00172 Salvage pyrimidine ribonucleotides#P02775>Uridine phosphorylase#P03152 CIOIN|Ensembl=ENSCING00000021096.1|UniProtKB=H2XMQ4 H2XMQ4 LOC100182286 PTHR43963:SF4 CARBONYL REDUCTASE 1-RELATED CARBONYL REDUCTASE (NADPH) oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 reductase#PC00198;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000002534.3|UniProtKB=F6XRF6 F6XRF6 PTHR45632:SF27 LD33804P KELCH-LIKE PROTEIN 9 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000003721.3|UniProtKB=F6W841 F6W841 PTHR44329:SF262 SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED RAF HOMOLOG SERINE_THREONINE-PROTEIN KINASE RAF MAP kinase kinase kinase activity#GO:0004709;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;MAPK cascade#GO:0000165;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;cellular process#GO:0009987;signaling#GO:0023052 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 VEGF signaling pathway#P00056>Raf#P01417;EGF receptor signaling pathway#P00018>Raf-1#P00560;PDGF signaling pathway#P00047>Raf#P01161;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Raf-1#P00843;Angiogenesis#P00005>Raf#P00243;Endothelin signaling pathway#P00019>Raf-1#P00587 CIOIN|Ensembl=ENSCING00000009475.3|UniProtKB=F7AEY7 F7AEY7 LOC100176942 PTHR14145:SF2 26S PROTESOME SUBUNIT 6 COP9 SIGNALOSOME COMPLEX SUBUNIT 1 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;COP9 signalosome#GO:0008180;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000001216.3|UniProtKB=F6SYV7 F6SYV7 PTHR14009:SF1 LEUCINE ZIPPER-EF-HAND CONTAINING TRANSMEMBRANE PROTEIN MITOCHONDRIAL PROTON_CALCIUM EXCHANGER PROTEIN intracellular monoatomic cation homeostasis#GO:0030003;homeostatic process#GO:0042592;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic ion homeostasis#GO:0006873;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;intracellular chemical homeostasis#GO:0055082;monoatomic ion homeostasis#GO:0050801 secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000011300.2|UniProtKB=F6XKF8 F6XKF8 LOC778698 PTHR24340:SF82 HOMEOBOX PROTEIN NKX HOMEOBOX PROTEIN VND sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 CIOIN|Ensembl=ENSCING00000025061.1|UniProtKB=H2XXW6 H2XXW6 LOC100181080 PTHR45791:SF1 CALCIUM AND INTEGRIN BINDING FAMILY MEMBER 2 CALCIUM AND INTEGRIN BINDING FAMILY MEMBER 1 CIOIN|Ensembl=ENSCING00000003118.4|UniProtKB=F6RD37 F6RD37 LOC100175171 PTHR21319:SF53 RING FINGER AND CHY ZINC FINGER DOMAIN-CONTAINING PROTEIN 1 RING FINGER AND CHY ZINC FINGER DOMAIN-CONTAINING PROTEIN 1 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 P53 pathway feedback loops 1#P04392>Pirh-2#P04538;P53 pathway feedback loops 1#P04392>Pirh-2#G04684 CIOIN|Ensembl=ENSCING00000008538.3|UniProtKB=F6YD09 F6YD09 PTHR45655:SF2 GUANYLATE CYCLASE SOLUBLE SUBUNIT BETA-2 GUANYLATE CYCLASE SOLUBLE SUBUNIT BETA-1 lyase activity#GO:0016829;cyclase activity#GO:0009975;phosphorus-oxygen lyase activity#GO:0016849;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;signal transduction#GO:0007165;cyclic nucleotide metabolic process#GO:0009187;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;response to abiotic stimulus#GO:0009628;signaling#GO:0023052;purine nucleotide metabolic process#GO:0006163;response to oxygen levels#GO:0070482;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cell communication#GO:0007154;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cGMP-mediated signaling#GO:0019934;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;response to stimulus#GO:0050896;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;cGMP biosynthetic process#GO:0006182;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleotide biosynthetic process#GO:0009152;cyclic-nucleotide-mediated signaling#GO:0019935;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622 guanylate cyclase#PC00114 Gonadotropin-releasing hormone receptor pathway#P06664>GC#P06726;Endothelin signaling pathway#P00019>Guanylate cyclase#P00581 CIOIN|Ensembl=ENSCING00000009166.3|UniProtKB=F6Z5E6 F6Z5E6 PTHR43718:SF2 LON PROTEASE LON PROTEASE HOMOLOG, MITOCHONDRIAL hydrolase activity#GO:0016787;peptidase activity#GO:0008233;ATP-dependent activity#GO:0140657;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule catabolic process#GO:0009057;protein quality control for misfolded or incompletely synthesized proteins#GO:0006515;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;catabolic process#GO:0009056;organonitrogen compound catabolic process#GO:1901565;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 serine protease#PC00203;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000004318.4|UniProtKB=F7BNX7 F7BNX7 LOC100184905 PTHR31363:SF0 TRAF3-INTERACTING PROTEIN 1 TRAF3-INTERACTING PROTEIN 1 regulation of microtubule-based process#GO:0032886;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;cell projection organization#GO:0030030;transport#GO:0006810;microtubule-based movement#GO:0007018;regulation of cellular component organization#GO:0051128;plasma membrane bounded cell projection organization#GO:0120036;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;establishment of localization#GO:0051234;cytoskeleton-dependent intracellular transport#GO:0030705;regulation of microtubule cytoskeleton organization#GO:0070507;cellular component assembly#GO:0022607;cilium assembly#GO:0060271;regulation of organelle organization#GO:0033043;cellular component organization#GO:0016043;cellular process#GO:0009987;transport along microtubule#GO:0010970;intraciliary transport#GO:0042073;cell projection assembly#GO:0030031;organelle assembly#GO:0070925;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;microtubule-based transport#GO:0099111;microtubule-based process#GO:0007017;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;protein-containing complex localization#GO:0031503 axoneme#GO:0005930;microtubule organizing center#GO:0005815;cytoplasmic region#GO:0099568;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intraciliary transport particle B#GO:0030992;microtubule cytoskeleton#GO:0015630;ciliary basal body#GO:0036064;ciliary plasm#GO:0097014;plasma membrane bounded cell projection cytoplasm#GO:0032838;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cytoskeleton#GO:0005856;cilium#GO:0005929;intraciliary transport particle#GO:0030990 CIOIN|Ensembl=ENSCING00000018174.1|UniProtKB=H2Y1B6 H2Y1B6 LOC100185836 PTHR11711:SF322 ADP RIBOSYLATION FACTOR-RELATED ADP-RIBOSYLATION FACTOR 6 carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167 cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 G-protein#PC00020 Integrin signalling pathway#P00034>Arf6#P00919;Huntington disease#P00029>ARF#P00786 CIOIN|Ensembl=ENSCING00000023066.1|UniProtKB=H2XTB5 H2XTB5 LOC100185942 PTHR11267:SF204 T-BOX PROTEIN-RELATED SPADETAIL sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cell fate commitment#GO:0045165;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;cell fate specification#GO:0001708;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;Rel homology transcription factor#PC00252;immunoglobulin fold transcription factor#PC00251 CIOIN|Ensembl=ENSCING00000002913.3|UniProtKB=F6SCE7 F6SCE7 PTHR12161:SF5 IST1 FAMILY MEMBER IST1 HOMOLOG localization#GO:0051179;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;cellular process#GO:0009987;macromolecule localization#GO:0033036;protein localization#GO:0008104 CIOIN|Ensembl=ENSCING00000019879.1|UniProtKB=H2Y1S4 H2Y1S4 PTHR24064:SF577 SOLUTE CARRIER FAMILY 22 MEMBER GH09241P secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000003597.3|UniProtKB=F6UYA6 F6UYA6 PTHR18934:SF91 ATP-DEPENDENT RNA HELICASE PRE-MRNA-SPLICING FACTOR ATP-DEPENDENT RNA HELICASE PRP16 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;helicase activity#GO:0004386;ATP-dependent activity#GO:0140657;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;catalytic activity, acting on a nucleic acid#GO:0140640 cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 RNA helicase#PC00032 CIOIN|Ensembl=ENSCING00000013667.2|UniProtKB=F6PY90 F6PY90 PTHR10627:SF69 SCP160 PROTEIN BICAUDAL C RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000002540.3|UniProtKB=F6XQX8 F6XQX8 PTHR24056:SF472 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE 4, ISOFORM A transferase activity#GO:0016740;cyclin-dependent protein kinase activity#GO:0097472;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;cyclin-dependent protein serine/threonine kinase activity#GO:0004693;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;protein binding#GO:0005515;cyclin binding#GO:0030332;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 signal transduction#GO:0007165;mitotic cell cycle phase transition#GO:0044772;macromolecule modification#GO:0043412;cell cycle G1/S phase transition#GO:0044843;cell cycle process#GO:0022402;protein modification process#GO:0036211;mitotic cell cycle process#GO:1903047;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;G1/S transition of mitotic cell cycle#GO:0000082;regulation of biological process#GO:0050789;mitotic cell cycle#GO:0000278;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;phosphorylation#GO:0016310;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;regulation of cell cycle G2/M phase transition#GO:1902749;regulation of mitotic cell cycle phase transition#GO:1901990;macromolecule metabolic process#GO:0043170;regulation of cell cycle phase transition#GO:1901987;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular process#GO:0009987;cell cycle phase transition#GO:0044770;primary metabolic process#GO:0044238;regulation of cell cycle process#GO:0010564;response to stimulus#GO:0050896;regulation of cellular biosynthetic process#GO:0031326;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;regulation of G2/M transition of mitotic cell cycle#GO:0010389;regulation of mitotic cell cycle#GO:0007346;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;protein kinase complex#GO:1902911;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695 non-receptor serine/threonine protein kinase#PC00167 CIOIN|Ensembl=ENSCING00000011487.2|UniProtKB=F6XHB2 F6XHB2 PTHR46134:SF3 DRONGO, ISOFORM F ARFGAP WITH FG REPEATS 1 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;membrane#GO:0016020;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000001956.3|UniProtKB=F6XTQ1 F6XTQ1 LOC100186125 PTHR10293:SF73 GLUTAREDOXIN FAMILY MEMBER GLUTAREDOXIN-3 inorganic ion homeostasis#GO:0098771;intracellular iron ion homeostasis#GO:0006879;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;homeostatic process#GO:0042592;intracellular monoatomic ion homeostasis#GO:0006873;chemical homeostasis#GO:0048878;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;monoatomic ion homeostasis#GO:0050801 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 reductase#PC00198;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000009519.3|UniProtKB=F6WWX5 F6WWX5 PTHR12542:SF41 EXOCYST COMPLEX PROTEIN EXO70 EXOCYST COMPLEX COMPONENT 7 localization#GO:0051179;exocytosis#GO:0006887;establishment of localization#GO:0051234;secretion#GO:0046903;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;export from cell#GO:0140352;secretion by cell#GO:0032940 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;vesicle tethering complex#GO:0099023;exocyst#GO:0000145;cell cortex#GO:0005938;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150 CIOIN|Ensembl=ENSCING00000006011.3|UniProtKB=F6SGR7 F6SGR7 PTHR46131:SF1 SD08549P SD08549P purine nucleotide transmembrane transporter activity#GO:0015216;nucleobase-containing compound transmembrane transporter activity#GO:0015932;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000018252.1|UniProtKB=H2XLA5 H2XLA5 PTHR11571:SF222 GLUTATHIONE S-TRANSFERASE GLUTATHIONE TRANSFERASE glutathione transferase activity#GO:0004364;transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824 sulfur compound metabolic process#GO:0006790;nitrogen compound metabolic process#GO:0006807;peptide metabolic process#GO:0006518;cellular modified amino acid metabolic process#GO:0006575;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular process#GO:0009987;glutathione metabolic process#GO:0006749;amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000004370.3|UniProtKB=F7BDW7 F7BDW7 PTHR24327:SF81 HOMEOBOX PROTEIN HOMEOTIC PROTEIN DISTAL-LESS-RELATED sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 homeodomain transcription factor#PC00119 CIOIN|Ensembl=ENSCING00000006451.3|UniProtKB=F6PGX9 F6PGX9 PTHR24223:SF443 ATP-BINDING CASSETTE SUB-FAMILY C MULTIDRUG-RESISTANCE LIKE PROTEIN 1, ISOFORM I transmembrane transporter activity#GO:0022857;primary active transmembrane transporter activity#GO:0015399;ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 localization#GO:0051179;establishment of localization#GO:0051234;cellular process#GO:0009987;transmembrane transport#GO:0055085;transport#GO:0006810 cellular anatomical entity#GO:0110165;membrane#GO:0016020 ATP-binding cassette (ABC) transporter#PC00003;transporter#PC00227 CIOIN|Ensembl=ENSCING00000008280.3|UniProtKB=A0A1W5BG44 A0A1W5BG44 LOC100187130 PTHR12573:SF4 AT09986P-RELATED AT09986P-RELATED CIOIN|Ensembl=ENSCING00000019349.1|UniProtKB=Q4H303 Q4H303 Ci-Otx PTHR45793:SF5 HOMEOBOX PROTEIN HOMEOTIC PROTEIN OCELLILESS sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 CIOIN|Ensembl=ENSCING00000014877.2|UniProtKB=F6ZA41 F6ZA41 PTHR24248:SF195 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR D(1) DOPAMINE RECEPTOR-LIKE signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of MAPK cascade#GO:0043408;signal transduction#GO:0007165;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;cell communication#GO:0007154;cellular process#GO:0009987;regulation of intracellular signal transduction#GO:1902531;positive regulation of MAPK cascade#GO:0043410;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 CIOIN|Ensembl=ENSCING00000006359.3|UniProtKB=F6RS66 F6RS66 PTHR44167:SF33 OVARIAN-SPECIFIC SERINE/THREONINE-PROTEIN KINASE LOK-RELATED NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;DNA damage checkpoint signaling#GO:0000077;mitotic cell cycle checkpoint signaling#GO:0007093;cell cycle process#GO:0022402;negative regulation of cell cycle process#GO:0010948;mitotic cell cycle process#GO:1903047;regulation of biological process#GO:0050789;cell cycle checkpoint signaling#GO:0000075;DNA damage response#GO:0006974;mitotic cell cycle#GO:0000278;signal transduction in response to DNA damage#GO:0042770;intracellular signal transduction#GO:0035556;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;cellular response to stimulus#GO:0051716;negative regulation of cell cycle#GO:0045786;negative regulation of cell cycle phase transition#GO:1901988;regulation of cell cycle phase transition#GO:1901987;negative regulation of mitotic cell cycle#GO:0045930;cell communication#GO:0007154;cellular process#GO:0009987;regulation of cell cycle process#GO:0010564;response to stimulus#GO:0050896;DNA integrity checkpoint signaling#GO:0031570;response to stress#GO:0006950;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;mitotic DNA integrity checkpoint signaling#GO:0044774;cellular response to stress#GO:0033554;regulation of mitotic cell cycle#GO:0007346;mitotic DNA damage checkpoint signaling#GO:0044773 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000007985.3|UniProtKB=F6W510 F6W510 PTHR45905:SF1 GOLGI-LOCALIZED, GAMMA-ADAPTIN EAR CONTAINING, ARF BINDING PROTEIN GOLGI-LOCALIZED, GAMMA-ADAPTIN EAR CONTAINING, ARF BINDING PROTEIN enzyme binding#GO:0019899;protein binding#GO:0005515;small GTPase binding#GO:0031267;binding#GO:0005488 localization#GO:0051179;localization within membrane#GO:0051668;cellular localization#GO:0051641;vesicle-mediated transport to the plasma membrane#GO:0098876;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;post-Golgi vesicle-mediated transport#GO:0006892;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;Golgi to plasma membrane transport#GO:0006893;protein localization#GO:0008104 cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;Golgi apparatus subcompartment#GO:0098791;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000020992.1|UniProtKB=H2XTH9 H2XTH9 PTHR11905:SF159 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN ADAM METALLOPROTEASE metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000003694.3|UniProtKB=F6XI84 F6XI84 PTHR24115:SF191 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF9 pyrophosphatase activity#GO:0016462;cytoskeletal protein binding#GO:0008092;microtubule motor activity#GO:0003777;tubulin binding#GO:0015631;ATP-dependent activity#GO:0140657;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;cytoskeletal motor activity#GO:0003774;microtubule binding#GO:0008017;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;ribonucleoside triphosphate phosphatase activity#GO:0017111;ATP hydrolysis activity#GO:0016887 microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;microtubule associated complex#GO:0005875;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 CIOIN|Ensembl=ENSCING00000015787.2|UniProtKB=F6SJ97 F6SJ97 PTHR32026:SF10 METHYLTRANSFERASE-LIKE PROTEIN 24 METHYLTRANSFERASE-LIKE PROTEIN 24-RELATED methyltransferase#PC00155 CIOIN|Ensembl=ENSCING00000007432.3|UniProtKB=F7APB5 F7APB5 PTHR10256:SF0 SELENIDE, WATER DIKINASE INACTIVE SELENIDE, WATER DIKINASE-LIKE PROTEIN-RELATED transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301 organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;proteinogenic amino acid metabolic process#GO:0170039;proteinogenic amino acid biosynthetic process#GO:0170038;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;alpha-amino acid biosynthetic process#GO:1901607;nitrogen compound metabolic process#GO:0006807;amino acid biosynthetic process#GO:0008652;alpha-amino acid metabolic process#GO:1901605;small molecule biosynthetic process#GO:0044283;L-amino acid biosynthetic process#GO:0170034;carboxylic acid metabolic process#GO:0019752;L-amino acid metabolic process#GO:0170033;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000013597.2|UniProtKB=F6VPH3 F6VPH3 LOC100181103 PTHR43885:SF1 HALOACID DEHALOGENASE-LIKE HYDROLASE SUPERFAMILY HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G13290)-RELATED metabolite interconversion enzyme#PC00262;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000021125.1|UniProtKB=H2XJV5 H2XJV5 LOC100183075 PTHR12002:SF116 CLAUDIN CLAUDIN-11-LIKE cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cell-cell junction organization#GO:0045216;cellular component biogenesis#GO:0044085;cell-cell junction assembly#GO:0007043;cell junction organization#GO:0034330;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;cell adhesion#GO:0007155;cellular process#GO:0009987 tight junction#GO:0070160;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cell junction#GO:0030054;bicellular tight junction#GO:0005923;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;apical junction complex#GO:0043296;plasma membrane#GO:0005886 cell junction protein#PC00070;tight junction#PC00214 CIOIN|Ensembl=ENSCING00000002672.3|UniProtKB=F6XQ02 F6XQ02 LOC100182906 PTHR10188:SF41 L-ASPARAGINASE ISOASPARTYL PEPTIDASE_L-ASPARAGINASE oxoacid metabolic process#GO:0043436;proteinogenic amino acid metabolic process#GO:0170039;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;amino acid catabolic process#GO:0009063;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;nitrogen compound metabolic process#GO:0006807;alpha-amino acid metabolic process#GO:1901605;catabolic process#GO:0009056;aspartate family amino acid metabolic process#GO:0009066;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;L-amino acid metabolic process#GO:0170033;carboxylic acid metabolic process#GO:0019752;amino acid metabolic process#GO:0006520;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 protease#PC00190;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000018223.1|UniProtKB=H2XLX5 H2XLX5 PTHR31698:SF8 LYSOZYME G FAMILY MEMBER LYSOZYME G-RELATED CIOIN|Ensembl=ENSCING00000005720.3|UniProtKB=F6U2U3 F6U2U3 LOC100176897 PTHR11922:SF2 GMP SYNTHASE-RELATED GMP SYNTHASE [GLUTAMINE-HYDROLYZING] ligase activity#GO:0016874;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;purine ribonucleoside monophosphate metabolic process#GO:0009167;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;nucleotide biosynthetic process#GO:0009165;nucleoside monophosphate metabolic process#GO:0009123;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;purine nucleoside monophosphate metabolic process#GO:0009126;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;ribonucleoside monophosphate metabolic process#GO:0009161;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ligase#PC00142;metabolite interconversion enzyme#PC00262 De novo purine biosynthesis#P02738>GMP synthase#P02899 CIOIN|Ensembl=ENSCING00000004492.3|UniProtKB=F7BBQ0 F7BBQ0 LOC100177058 PTHR10381:SF11 ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT, MITOCHONDRIAL serine-type endopeptidase activity#GO:0004252;ATP-dependent activity#GO:0140657;binding#GO:0005488;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;enzyme binding#GO:0019899;protein binding#GO:0005515;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 macromolecule catabolic process#GO:0009057;protein quality control for misfolded or incompletely synthesized proteins#GO:0006515;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;catabolic process#GO:0009056;organonitrogen compound catabolic process#GO:1901565;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 protein-containing complex#GO:0032991;catalytic complex#GO:1902494 serine protease#PC00203;protease#PC00190 CIOIN|Ensembl=ENSCING00000014328.2|UniProtKB=F6TZM3 F6TZM3 PTHR11866:SF34 G-PROTEIN COUPLED RECEPTOR FAMILY 1 MEMBER G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 CIOIN|Ensembl=ENSCING00000012745.2|UniProtKB=F7A8Z2 F7A8Z2 LOC113474123 PTHR45618:SF8 MITOCHONDRIAL DICARBOXYLATE CARRIER-RELATED MITOCHONDRIAL UNCOUPLING PROTEIN 4 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 response to cold#GO:0009409;response to stimulus#GO:0050896;response to temperature stimulus#GO:0009266;response to abiotic stimulus#GO:0009628;response to stress#GO:0006950 secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000009504.3|UniProtKB=F6XKA2 F6XKA2 PTHR22808:SF1 NCL1 YEAST -RELATED NOL1/NOP2/FMU SUN DOMAIN-CONTAINING RNA CYTOSINE-C(5)-METHYLTRANSFERASE NSUN2-RELATED methyltransferase activity#GO:0008168;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;RNA modification#GO:0009451;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;methylation#GO:0032259;macromolecule methylation#GO:0043414;nitrogen compound metabolic process#GO:0006807;RNA methylation#GO:0001510;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 RNA methyltransferase#PC00033 CIOIN|Ensembl=ENSCING00000003595.3|UniProtKB=F6YVL2 F6YVL2 LOC100183862 PTHR14167:SF81 SH3 DOMAIN-CONTAINING ENDOPHILIN-A scaffold/adaptor protein#PC00226 CIOIN|Gene=RPS23|UniProtKB=Q8I7D5 Q8I7D5 RPS23 PTHR11652:SF14 30S RIBOSOMAL PROTEIN S12 FAMILY MEMBER SMALL RIBOSOMAL SUBUNIT PROTEIN US12 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic small ribosomal subunit#GO:0022627;cytosol#GO:0005829;small ribosomal subunit#GO:0015935;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000003722.3|UniProtKB=Q4H3W9 Q4H3W9 Ci-AP-2-like2 PTHR10812:SF17 TRANSCRIPTION FACTOR AP-2 TRANSCRIPTION FACTOR AP-2, ISOFORM D sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of cell population proliferation#GO:0042127;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031;general transcription factor#PC00259 CIOIN|Ensembl=ENSCING00000019194.1|UniProtKB=Q4H3B1 Q4H3B1 Ci-IRF-like-6 PTHR11949:SF53 INTERFERON REGULATORY FACTOR IRF TRYPTOPHAN PENTAD REPEAT DOMAIN-CONTAINING PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 CIOIN|Ensembl=ENSCING00000006189.3|UniProtKB=F7B1W8 F7B1W8 PTHR11178:SF1 IRON-SULFUR CLUSTER SCAFFOLD PROTEIN NFU-RELATED NFU1 IRON-SULFUR CLUSTER SCAFFOLD HOMOLOG, MITOCHONDRIAL CIOIN|Ensembl=ENSCING00000001241.3|UniProtKB=F7AEV2 F7AEV2 LOC100179260 PTHR12058:SF0 ARP2/3 COMPLEX 34 KDA SUBUNIT ACTIN-RELATED PROTEIN 2_3 COMPLEX SUBUNIT 2 cytoskeletal protein binding#GO:0008092;structural molecule activity#GO:0005198;binding#GO:0005488;actin filament binding#GO:0051015;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;structural constituent of cytoskeleton#GO:0005200;actin binding#GO:0003779 cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;Arp2/3 complex-mediated actin nucleation#GO:0034314;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;Arp2/3 protein complex#GO:0005885;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 Integrin signalling pathway#P00034>Arp2/3#P00912;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Arp2/3#P00876;Cytoskeletal regulation by Rho GTPase#P00016>ARP2/3#P00511 CIOIN|Ensembl=ENSCING00000006878.3|UniProtKB=F6YUE7 F6YUE7 PTHR18934:SF136 ATP-DEPENDENT RNA HELICASE ATP-DEPENDENT RNA HELICASE DHX35-RELATED nucleic acid binding#GO:0003676;RNA binding#GO:0003723;helicase activity#GO:0004386;ATP-dependent activity#GO:0140657;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;catalytic activity, acting on a nucleic acid#GO:0140640 cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 RNA helicase#PC00032 CIOIN|Ensembl=ENSCING00000013640.2|UniProtKB=F6UC91 F6UC91 PTHR11937:SF387 ACTIN ACTIN-LIKE PROTEIN 53D intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 actin and actin related protein#PC00039;cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 Wnt signaling pathway#P00057>NFAT Target Genes#G01559;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>F-actin#P00858;Alzheimer disease-presenilin pathway#P00004>actin#P00114;Integrin signalling pathway#P00034>Actin#P00944;Huntington disease#P00029>Actin#P00807;Nicotinic acetylcholine receptor signaling pathway#P00044>Actin#P01090;Cadherin signaling pathway#P00012>F-actin#P00470;Cytoskeletal regulation by Rho GTPase#P00016>Actin#P00512 CIOIN|Ensembl=ENSCING00000012976.2|UniProtKB=F6RB73 F6RB73 LOC100178327 PTHR22802:SF396 C-TYPE LECTIN SUPERFAMILY MEMBER C-TYPE LECTIN DOMAIN-CONTAINING PROTEIN membrane traffic protein#PC00150 CIOIN|Ensembl=ENSCING00000002638.3|UniProtKB=F7B2D4 F7B2D4 PTHR21470:SF2 RAB6-INTERACTING PROTEIN GORAB RAB6-INTERACTING GOLGIN CIOIN|Ensembl=ENSCING00000001688.3|UniProtKB=F6UJS3 F6UJS3 LOC100178722 PTHR10799:SF964 SNF2/RAD54 HELICASE FAMILY SWI_SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY A CONTAINING DEAD_H BOX 1 ATP-dependent activity, acting on DNA#GO:0008094;nucleic acid binding#GO:0003676;ATP-dependent activity#GO:0140657;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;chromatin binding#GO:0003682;DNA binding#GO:0003677;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on DNA#GO:0140097;protein-containing complex binding#GO:0044877 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-DNA complex#GO:0032993;chromosome#GO:0005694;chromatin#GO:0000785;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA helicase#PC00011;DNA metabolism protein#PC00009 CIOIN|Ensembl=ENSCING00000006972.3|UniProtKB=F6SZ94 F6SZ94 PTHR11010:SF38 PROTEASE S28 PRO-X CARBOXYPEPTIDASE-RELATED LYSOSOMAL PRO-X CARBOXYPEPTIDASE hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 serine protease#PC00203;protease#PC00190 CIOIN|Ensembl=ENSCING00000005173.3|UniProtKB=F6RWX2 F6RWX2 PTHR22298:SF29 ENDO-1,4-BETA-GLUCANASE ENDOGLUCANASE CIOIN|Ensembl=ENSCING00000012728.2|UniProtKB=L7N0U5 L7N0U5 PTHR20765:SF1 SOLUTE CARRIER FAMILY 43 MEMBER 3-RELATED EQUILIBRATIVE NUCLEOBASE TRANSPORTER 1 amino acid transporter#PC00046;secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000000065.3|UniProtKB=F6V6G1 F6V6G1 PTHR11590:SF81 PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE K-LIKE ISOFORM X4 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000007667.3|UniProtKB=F6T7J7 F6T7J7 LOC100176093 PTHR24068:SF168 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 J1 ubiquitin-like protein conjugating enzyme activity#GO:0061650;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin conjugating enzyme activity#GO:0061631;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein polyubiquitination#GO:0000209;post-translational protein modification#GO:0043687;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000005113.3|UniProtKB=F6VYC6 F6VYC6 LOC100178583 PTHR11586:SF43 TRNA-AMINOACYLATION COFACTOR ARC1 FAMILY MEMBER TYROSINE--TRNA LIGASE, CYTOPLASMIC catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on RNA#GO:0140098;ligase activity#GO:0016874;catalytic activity#GO:0003824 translational protein#PC00263 CIOIN|Ensembl=ENSCING00000006443.3|UniProtKB=F6QL27 F6QL27 PTHR14002:SF54 ENDOGLIN/TGF-BETA RECEPTOR TYPE III ZONA PELLUCIDA SPERM-BINDING PROTEIN 2 transmembrane signal receptor#PC00197 CIOIN|Ensembl=ENSCING00000019088.1|UniProtKB=H2XRC4 H2XRC4 PTHR16222:SF24 ADP-RIBOSYLGLYCOHYDROLASE ADP-RIBOSYLHYDROLASE ARH3 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000008164.3|UniProtKB=F6UQL0 F6UQL0 LOC100175542 PTHR45625:SF1 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-RELATED RING-TYPE E3 UBIQUITIN-PROTEIN LIGASE PPIL2 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;peptidyl-prolyl cis-trans isomerase activity#GO:0003755;aminoacyltransferase activity#GO:0016755;isomerase activity#GO:0016853;catalytic activity, acting on a protein#GO:0140096 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein peptidyl-prolyl isomerization#GO:0000413;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein polyubiquitination#GO:0000209;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 ribonucleoprotein complex#GO:1990904;catalytic step 2 spliceosome#GO:0071013;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chaperone#PC00072 CIOIN|Ensembl=ENSCING00000018828|UniProtKB=Q8I7D9 Q8I7D9 SEC61G PTHR12309:SF5 SEC61 GAMMA SUBUNIT PROTEIN TRANSPORT PROTEIN SEC61 SUBUNIT GAMMA protein transmembrane transporter activity#GO:0008320;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 localization within membrane#GO:0051668;cellular localization#GO:0051641;intracellular protein transmembrane transport#GO:0065002;protein localization to endoplasmic reticulum#GO:0070972;transmembrane transport#GO:0055085;macromolecule localization#GO:0033036;post-translational protein targeting to membrane, translocation#GO:0031204;protein localization to membrane#GO:0072657;transport#GO:0006810;protein transmembrane transport#GO:0071806;protein targeting#GO:0006605;nitrogen compound transport#GO:0071705;protein targeting to ER#GO:0045047;establishment of protein localization to organelle#GO:0072594;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;organic substance transport#GO:0071702;establishment of protein localization to membrane#GO:0090150;post-translational protein targeting to endoplasmic reticulum membrane#GO:0006620;protein targeting to membrane#GO:0006612;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;protein localization to organelle#GO:0033365;establishment of protein localization to endoplasmic reticulum#GO:0072599 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;endoplasmic reticulum protein-containing complex#GO:0140534;rough endoplasmic reticulum membrane#GO:0030867;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;rough endoplasmic reticulum#GO:0005791;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 primary active transporter#PC00068;transporter#PC00227 CIOIN|Ensembl=ENSCING00000008670.3|UniProtKB=F6ZFE0 F6ZFE0 vgat PTHR48017:SF206 OS05G0424000 PROTEIN-RELATED VESICULAR INHIBITORY AMINO ACID TRANSPORTER CIOIN|Ensembl=ENSCING00000005621.3|UniProtKB=F7AT31 F7AT31 LOC100187274 PTHR10104:SF20 STATHMIN STATHMIN DOMAIN-CONTAINING PROTEIN 1 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 CIOIN|Ensembl=ENSCING00000016407.2|UniProtKB=F6S473 F6S473 PTHR12369:SF17 CHONDROITIN SYNTHASE CHONDROITIN SULFATE SYNTHASE 1-LIKE transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;UDP-glycosyltransferase activity#GO:0008194 glycoprotein biosynthetic process#GO:0009101;glycosaminoglycan metabolic process#GO:0030203;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;chondroitin sulfate proteoglycan biosynthetic process#GO:0050650;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;proteoglycan metabolic process#GO:0006029;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;proteoglycan biosynthetic process#GO:0030166;nitrogen compound metabolic process#GO:0006807;aminoglycan biosynthetic process#GO:0006023;glycosaminoglycan biosynthetic process#GO:0006024;aminoglycan metabolic process#GO:0006022;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 glycosyltransferase#PC00111 CIOIN|Ensembl=ENSCING00000012616.2|UniProtKB=F6XEI5 F6XEI5 PTHR22906:SF43 PROPERDIN PROPERDIN CIOIN|Ensembl=ENSCING00000018657.1|UniProtKB=H2XX22 H2XX22 PTHR10663:SF402 GUANYL-NUCLEOTIDE EXCHANGE FACTOR MIP16918P guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 CIOIN|Ensembl=ENSCING00000022161.1|UniProtKB=H2Y3A4 H2Y3A4 PTHR24300:SF397 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 2U1 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;tetrapyrrole binding#GO:0046906;steroid hydroxylase activity#GO:0008395;oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497;heme binding#GO:0020037 response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;response to chemical#GO:0042221;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 oxygenase#PC00177;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000006006.3|UniProtKB=F6SG33 F6SG33 PTHR10196:SF69 SUGAR KINASE GLYCEROL KINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301 organic hydroxy compound metabolic process#GO:1901615;cellular metabolic process#GO:0044237;phosphorylation#GO:0016310;alcohol metabolic process#GO:0006066;cellular process#GO:0009987;carbohydrate metabolic process#GO:0005975;phosphorus metabolic process#GO:0006793;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 carbohydrate kinase#PC00065 CIOIN|Ensembl=ENSCING00000024487.1|UniProtKB=H2XMZ0 H2XMZ0 LOC100178422 PTHR10258:SF8 CALCIUM-ACTIVATED POTASSIUM CHANNEL SUBUNIT BETA CALCIUM-ACTIVATED POTASSIUM CHANNEL BK ALPHA SUBUNIT DOMAIN-CONTAINING PROTEIN monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;potassium ion transmembrane transporter activity#GO:0015079;molecular function regulator activity#GO:0098772;transporter regulator activity#GO:0141108;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;channel activity#GO:0015267;monoatomic ion-gated channel activity#GO:0022839;calcium-activated potassium channel activity#GO:0015269;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;calcium-activated cation channel activity#GO:0005227;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;potassium channel regulator activity#GO:0015459;ligand-gated monoatomic cation channel activity#GO:0099094;channel regulator activity#GO:0016247;monoatomic ion channel activity#GO:0005216;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion transmembrane transporter activity#GO:0015075;ligand-gated channel activity#GO:0022834 detection of stimulus#GO:0051606;response to stimulus#GO:0050896;response to chemical#GO:0042221;detection of chemical stimulus#GO:0009593 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;voltage-gated potassium channel complex#GO:0008076;cation channel complex#GO:0034703;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227;voltage-gated ion channel#PC00241 CIOIN|Ensembl=ENSCING00000021456.1|UniProtKB=H2XVM5 H2XVM5 PTHR23310:SF62 ACYL-COA-BINDING PROTEIN, ACBP ACYL-COA BINDING PROTEIN 1, ISOFORM A carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;amide binding#GO:0033218;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;lipid binding#GO:0008289;anion binding#GO:0043168;ion binding#GO:0043167 lipid metabolic process#GO:0006629;oxoacid metabolic process#GO:0043436;fatty acid metabolic process#GO:0006631;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular lipid metabolic process#GO:0044255;organic acid metabolic process#GO:0006082;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 transfer/carrier protein#PC00219 CIOIN|Ensembl=ENSCING00000001367.3|UniProtKB=F6SWL4 F6SWL4 PTHR10799:SF1001 SNF2/RAD54 HELICASE FAMILY BTAF (TBP-ASSOCIATED FACTOR) HOMOLOG ATP-dependent activity, acting on DNA#GO:0008094;nucleic acid binding#GO:0003676;ATP-dependent activity#GO:0140657;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on DNA#GO:0140097 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-DNA complex#GO:0032993;chromosome#GO:0005694;chromatin#GO:0000785;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA helicase#PC00011;DNA metabolism protein#PC00009 CIOIN|Ensembl=ENSCING00000019572.1|UniProtKB=H2XL14 H2XL14 PTHR12290:SF11 CORNICHON-RELATED PROTEIN CORNICHON membrane traffic protein#PC00150 CIOIN|Ensembl=ENSCING00000009106.3|UniProtKB=F6Q966 F6Q966 PTHR20765:SF1 SOLUTE CARRIER FAMILY 43 MEMBER 3-RELATED EQUILIBRATIVE NUCLEOBASE TRANSPORTER 1 amino acid transporter#PC00046;secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000020172.1|UniProtKB=H2XWM6 H2XWM6 PTHR13608:SF3 ARMADILLO-LIKE HELICAL DOMAIN-CONTAINING PROTEIN 3 ARMADILLO-LIKE HELICAL DOMAIN-CONTAINING PROTEIN 3 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000018089.1|UniProtKB=H2XTM4 H2XTM4 PTHR46074:SF5 CYSTEINE-RICH PROTEIN CRIP FAMILY MEMBER LIM DOMAIN-CONTAINING PROTEIN C cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 CIOIN|Ensembl=ENSCING00000004039.3|UniProtKB=F6RYF3 F6RYF3 neurogenin PTHR19290:SF163 BASIC HELIX-LOOP-HELIX PROTEIN NEUROGENIN-RELATED BASIC HELIX-LOOP-HELIX NEURAL TRANSCRIPTION FACTOR TAP sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of nitrogen compound metabolic process#GO:0051173;neurogenesis#GO:0022008;positive regulation of RNA biosynthetic process#GO:1902680;cell projection organization#GO:0030030;regulation of nitrogen compound metabolic process#GO:0051171;animal organ development#GO:0048513;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;neuron differentiation#GO:0030182;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;multicellular organism development#GO:0007275;cellular component organization#GO:0016043;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;anatomical structure development#GO:0048856;biological regulation#GO:0065007;neuron development#GO:0048666;multicellular organismal process#GO:0032501;positive regulation of RNA metabolic process#GO:0051254;generation of neurons#GO:0048699;sensory organ development#GO:0007423;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;basic helix-loop-helix transcription factor#PC00055 CIOIN|Ensembl=ENSCING00000013420.2|UniProtKB=F6V3K9 F6V3K9 LOC100184506 PTHR11567:SF202 ACID PHOSPHATASE-RELATED LYSOPHOSPHATIDIC ACID PHOSPHATASE TYPE 6 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 cellular metabolic process#GO:0044237;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;dephosphorylation#GO:0016311;metabolic process#GO:0008152 metabolite interconversion enzyme#PC00262;phosphatase#PC00181 CIOIN|Ensembl=ENSCING00000009081.3|UniProtKB=F6VP14 F6VP14 PTHR22957:SF27 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER 13 nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 cellular localization#GO:0051641;macromolecule localization#GO:0033036;regulation of GTPase activity#GO:0043087;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;transport#GO:0006810;activation of GTPase activity#GO:0090630;positive regulation of molecular function#GO:0044093;nitrogen compound transport#GO:0071705;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;establishment of protein localization#GO:0045184;positive regulation of hydrolase activity#GO:0051345;protein localization#GO:0008104;localization#GO:0051179;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;regulation of molecular function#GO:0065009;protein transport#GO:0015031;biological regulation#GO:0065007;regulation of hydrolase activity#GO:0051336;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 GTPase-activating protein#PC00257 CIOIN|Ensembl=ENSCING00000001808.3|UniProtKB=F6X598 F6X598 LOC100176872 PTHR13178:SF0 NADH-UBIQUINONE OXIDOREDUCTASE SGDH SUBUNIT NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 5, MITOCHONDRIAL envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;respiratory chain complex#GO:0098803;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transporter complex#GO:1990351;oxidoreductase complex#GO:1990204;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;respirasome#GO:0070469;mitochondrial respiratory chain complex I#GO:0005747;protein-containing complex#GO:0032991;mitochondrial envelope#GO:0005740;inner mitochondrial membrane protein complex#GO:0098800;transmembrane transporter complex#GO:1902495;mitochondrial respirasome#GO:0005746;membrane-bounded organelle#GO:0043227;respiratory chain complex I#GO:0045271;NADH dehydrogenase complex#GO:0030964;mitochondrial protein-containing complex#GO:0098798 oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000019950.1|UniProtKB=F6VE11 F6VE11 LOC100187272 PTHR24412:SF172 KELCH PROTEIN KELCH-LIKE PROTEIN 10 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000001572.3|UniProtKB=F6VC80 F6VC80 PTHR10937:SF0 GLUCOSAMINE--FRUCTOSE-6-PHOSPHATE AMINOTRANSFERASE, ISOMERIZING GLUTAMINE--FRUCTOSE-6-PHOSPHATE TRANSAMINASE (ISOMERIZING) transaminase activity#GO:0008483;transferase activity#GO:0016740;catalytic activity#GO:0003824 glycoprotein biosynthetic process#GO:0009101;cellular aromatic compound metabolic process#GO:0006725;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule modification#GO:0043412;protein modification process#GO:0036211;biosynthetic process#GO:0009058;nucleotide-sugar metabolic process#GO:0009225;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein glycosylation#GO:0006486;UDP-N-acetylglucosamine metabolic process#GO:0006047;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;protein N-linked glycosylation#GO:0006487;amino sugar metabolic process#GO:0006040;organophosphate metabolic process#GO:0019637;nucleobase-containing small molecule metabolic process#GO:0055086;glycosylation#GO:0070085;small molecule metabolic process#GO:0044281 transaminase#PC00216 O-antigen biosynthesis#P02757>Fructose-6-phosphate aminotransferase#P03051;N-acetylglucosamine metabolism#P02756>Fructose-6-phosphate aminotransferase#P03042;De novo purine biosynthesis#P02738>Amidophosphoribosyl transferase#P02905 CIOIN|Ensembl=ENSCING00000002567.3|UniProtKB=F6UF05 F6UF05 zf(cchc)-15 PTHR11538:SF40 PHENYLALANYL-TRNA SYNTHETASE PHENYLALANINE--TRNA LIGASE ALPHA SUBUNIT catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;ligase activity#GO:0016874;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;peptide biosynthetic process#GO:0043043;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 aminoacyl-tRNA synthetase#PC00047 CIOIN|Ensembl=ENSCING00000009086.3|UniProtKB=F6QEH8 F6QEH8 LOC100177801 PTHR13186:SF0 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 31 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 31 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;core mediator complex#GO:0070847;RNA polymerase II transcription regulator complex#GO:0090575;mediator complex#GO:0016592;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031;general transcription factor#PC00259 CIOIN|Ensembl=ENSCING00000024016.1|UniProtKB=H2XX96 H2XX96 PTHR43735:SF3 APOPTOSIS-INDUCING FACTOR 1 FERROPTOSIS SUPPRESSOR PROTEIN 1 nucleotide binding#GO:0000166;electron transfer activity#GO:0009055;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;flavin adenine dinucleotide binding#GO:0050660;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167;oxidoreductase activity#GO:0016491 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 p53 pathway#P00059>NOXA#G01572 CIOIN|Ensembl=ENSCING00000009913.2|UniProtKB=F6RAC0 F6RAC0 PTHR11339:SF386 EXTRACELLULAR MATRIX GLYCOPROTEIN RELATED HEMOLECTIN, ISOFORM A external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 extracellular matrix protein#PC00102 CIOIN|Ensembl=ENSCING00000020000.1|UniProtKB=H2XLJ6 H2XLJ6 LOC100179250 PTHR14167:SF76 SH3 DOMAIN-CONTAINING ENDOPHILIN B, ISOFORM A cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;cellular process#GO:0009987;membrane organization#GO:0061024 cellular anatomical entity#GO:0110165;membrane#GO:0016020 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000007344.3|UniProtKB=F6XYE9 F6XYE9 PTHR10454:SF232 CASPASE AT03047P-RELATED cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197;hydrolase activity#GO:0016787;cysteine-type endopeptidase activity involved in apoptotic process#GO:0097153;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 regulation of biological process#GO:0050789;positive regulation of apoptotic process#GO:0043065;positive regulation of programmed cell death#GO:0043068;regulation of apoptotic process#GO:0042981;regulation of cellular process#GO:0050794;apoptotic process#GO:0006915;biological regulation#GO:0065007;cell death#GO:0008219;programmed cell death#GO:0012501;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;regulation of programmed cell death#GO:0043067;positive regulation of cellular process#GO:0048522 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 protease#PC00190;protein modifying enzyme#PC00260 FAS signaling pathway#P00020>Caspase6#P00596;FAS signaling pathway#P00020>Pro-Caspase6#P00607 CIOIN|Ensembl=ENSCING00000001957.4|UniProtKB=F6XTJ3 F6XTJ3 PTHR45759:SF1 NUCLEOLAR GTP-BINDING PROTEIN 1 GTP-BINDING PROTEIN 4 GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111 cellular component organization or biogenesis#GO:0071840;cellular component biogenesis#GO:0044085;ribosome biogenesis#GO:0042254;cellular process#GO:0009987;ribosomal large subunit biogenesis#GO:0042273;ribonucleoprotein complex biogenesis#GO:0022613 CIOIN|Ensembl=ENSCING00000001658.3|UniProtKB=F7AEU0 F7AEU0 PTHR20929:SF11 LUNG ADENOMA SUSCEPTIBILITY 1-RELATED DYNEIN AXONEMAL INTERMEDIATE CHAIN 7 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 axoneme#GO:0005930;cytoplasmic region#GO:0099568;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;plasma membrane bounded cell projection cytoplasm#GO:0032838;ciliary plasm#GO:0097014;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cytoskeleton#GO:0005856;cilium#GO:0005929 CIOIN|Ensembl=ENSCING00000004767.3|UniProtKB=F6PM95 F6PM95 PTHR44411:SF1 THO COMPLEX SUBUNIT 6 HOMOLOG THO COMPLEX SUBUNIT 6 HOMOLOG mRNA export from nucleus#GO:0006406;cellular localization#GO:0051641;macromolecule biosynthetic process#GO:0009059;macromolecule localization#GO:0033036;establishment of RNA localization#GO:0051236;macromolecule metabolic process#GO:0043170;transport#GO:0006810;nucleic acid transport#GO:0050657;nitrogen compound transport#GO:0071705;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;mRNA transport#GO:0051028;RNA localization#GO:0006403;localization#GO:0051179;organic substance transport#GO:0071702;nuclear export#GO:0051168;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;RNA transport#GO:0050658;nucleobase-containing compound transport#GO:0015931;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;nuclear transport#GO:0051169;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;THO complex#GO:0000347;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;transcription export complex#GO:0000346;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000008189.3|UniProtKB=F6VDE1 F6VDE1 PTHR10824:SF4 ACYL-COENZYME A THIOESTERASE-RELATED ACYL-COENZYME A THIOESTERASE 1-LIKE hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;fatty acyl-CoA hydrolase activity#GO:0047617;catalytic activity#GO:0003824;thiolester hydrolase activity#GO:0016790 cellular aromatic compound metabolic process#GO:0006725;lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;amide metabolic process#GO:0043603;purine nucleotide metabolic process#GO:0006163;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;acyl-CoA metabolic process#GO:0006637;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;ribonucleotide metabolic process#GO:0009259;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;purine ribonucleotide metabolic process#GO:0009150;fatty acid metabolic process#GO:0006631;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 esterase#PC00097 CIOIN|Ensembl=ENSCING00000022355.1|UniProtKB=H2XXJ0 H2XXJ0 PTHR12372:SF6 PECANEX PECANEX-LIKE PROTEIN 4 CIOIN|Ensembl=ENSCING00000008293.3|UniProtKB=F6QCQ5 F6QCQ5 LOC100187134 PTHR12150:SF13 CLASS IV SAM-BINDING METHYLTRANSFERASE-RELATED METHYLTRANSFERASE C9ORF114-RELATED methyltransferase#PC00155 CIOIN|Ensembl=ENSCING00000004760.3|UniProtKB=F6PMM3 F6PMM3 PTHR10693:SF20 RAS GTPASE-ACTIVATING PROTEIN-BINDING PROTEIN AT27578P nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;cytosol#GO:0005829;protein-containing complex#GO:0032991;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000014677.2|UniProtKB=F6ZW37 F6ZW37 LOC100178124 PTHR43028:SF4 3'(2'),5'-BISPHOSPHATE NUCLEOTIDASE 1 INOSITOL MONOPHOSPHATASE 3 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;nucleotidase activity#GO:0008252;phosphoric ester hydrolase activity#GO:0042578 cellular anatomical entity#GO:0110165;endomembrane system#GO:0012505 phosphatase#PC00181;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000003643.3|UniProtKB=F6TJZ3 F6TJZ3 LOC100186233 PTHR24104:SF49 E3 UBIQUITIN-PROTEIN LIGASE NHLRC1-RELATED BRAIN TUMOR PROTEIN-LIKE transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein polyubiquitination#GO:0000209;proteasomal protein catabolic process#GO:0010498;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000006065.3|UniProtKB=F6ZGT8 F6ZGT8 LOC100176704 PTHR12806:SF0 EAP30 SUBUNIT OF ELL COMPLEX VACUOLAR-SORTING PROTEIN SNF8 endosomal transport#GO:0016197;cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;protein catabolic process#GO:0030163;late endosome to vacuole transport via multivesicular body sorting pathway#GO:0032511;nitrogen compound transport#GO:0071705;organonitrogen compound catabolic process#GO:1901565;late endosome to vacuole transport#GO:0045324;protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043328;establishment of protein localization#GO:0045184;ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043162;modification-dependent macromolecule catabolic process#GO:0043632;organic substance transport#GO:0071702;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;protein localization to organelle#GO:0033365;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;establishment of protein localization to vacuole#GO:0072666;modification-dependent protein catabolic process#GO:0019941;vacuolar transport#GO:0007034;macromolecule metabolic process#GO:0043170;protein localization to vacuole#GO:0072665;organonitrogen compound metabolic process#GO:1901564;establishment of protein localization to organelle#GO:0072594;vesicle-mediated transport#GO:0016192;multivesicular body sorting pathway#GO:0071985;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein localization#GO:0008104;ubiquitin-dependent protein catabolic process#GO:0006511;localization#GO:0051179;cellular macromolecule localization#GO:0070727;protein transport#GO:0015031;endosome transport via multivesicular body sorting pathway#GO:0032509;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;endosome#GO:0005768;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endosome membrane#GO:0010008;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cytoplasmic vesicle membrane#GO:0030659 CIOIN|Ensembl=ENSCING00000005501.3|UniProtKB=F7BDP7 F7BDP7 PTHR43975:SF2 ZGC:101858 EG:BACR7A4.14 PROTEIN-RELATED CIOIN|Ensembl=ENSCING00000009930.3|UniProtKB=F6R675 F6R675 LOC100176328 PTHR36978:SF4 P-LOOP CONTAINING NUCLEOTIDE TRIPHOSPHATE HYDROLASE P-LOOP CONTAINING NUCLEOSIDE TRIPHOSPHATE HYDROLASE PROTEIN metabolite interconversion enzyme#PC00262;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000007283.3|UniProtKB=F6SV73 F6SV73 PTHR13563:SF19 TRNA (GUANINE-9-) METHYLTRANSFERASE TRNA METHYLTRANSFERASE 10 HOMOLOG B tRNA binding#GO:0000049;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA modification#GO:0009451;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;tRNA modification#GO:0006400;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;macromolecule methylation#GO:0043414;tRNA methylation#GO:0030488;organic cyclic compound metabolic process#GO:1901360;methylation#GO:0032259;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;RNA methylation#GO:0001510;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA methyltransferase#PC00033 CIOIN|Ensembl=ENSCING00000008043.3|UniProtKB=F6S4F7 F6S4F7 PTHR24356:SF407 SERINE/THREONINE-PROTEIN KINASE RAC SERINE_THREONINE-PROTEIN KINASE transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular process#GO:0009987;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 VEGF signaling pathway#P00056>Akt/PKB#P01408;Angiogenesis#P00005>Akt#P00223;p53 pathway feedback loops 2#P04398>AKT#P04665;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>AKT#P00827;Hypoxia response via HIF activation#P00030>AKT#P00819;EGF receptor signaling pathway#P00018>Akt#P00551;p53 pathway#P00059>Akt#P01486;PI3 kinase pathway#P00048>PKB#P01179;FAS signaling pathway#P00020>ASK1#P00614;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>AKT#P00894;Apoptosis signaling pathway#P00006>AKT#P00260;p53 pathway by glucose deprivation#P04397>Akt#P04641;Endothelin signaling pathway#P00019>Akt#P00589;FGF signaling pathway#P00021>Akt#P00632 CIOIN|Ensembl=ENSCING00000008154.3|UniProtKB=F6VF91 F6VF91 LOC100176333 PTHR11570:SF0 S-ADENOSYLMETHIONINE DECARBOXYLASE S-ADENOSYLMETHIONINE DECARBOXYLASE PROENZYME decarboxylase#PC00089;lyase#PC00144 CIOIN|Ensembl=ENSCING00000000627.3|UniProtKB=F6RRE5 F6RRE5 LOC100184552 PTHR23050:SF518 CALCIUM BINDING PROTEIN AT16150P-RELATED cation binding#GO:0043169;small molecule binding#GO:0036094;molecular function regulator activity#GO:0098772;binding#GO:0005488;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;enzyme regulator activity#GO:0030234 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 calmodulin-related#PC00061 B cell activation#P00010>Calmodulin#P00375;Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Calmodulin#P00755;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Phosphorylase b kinase#P00716;T cell activation#P00053>Calmodulin#P01305 CIOIN|Ensembl=ENSCING00000009145.3|UniProtKB=F7BBF0 F7BBF0 PTHR43213:SF5 BIFUNCTIONAL DTTP/UTP PYROPHOSPHATASE/METHYLTRANSFERASE PROTEIN-RELATED BIFUNCTIONAL DTTP_UTP PYROPHOSPHATASE_METHYLTRANSFERASE PROTEIN-RELATED pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824 CIOIN|Ensembl=ENSCING00000022811.1|UniProtKB=H2XW65 H2XW65 LOC100175581 PTHR15090:SF0 SEQUESTOSOME 1-RELATED SEQUESTOSOME-1 K63-linked polyubiquitin modification-dependent protein binding#GO:0070530;binding#GO:0005488;protein binding#GO:0005515;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;modification-dependent protein binding#GO:0140030;polyubiquitin modification-dependent protein binding#GO:0031593;kinase binding#GO:0019900 macroautophagy#GO:0016236;mitophagy#GO:0000423;endomembrane system organization#GO:0010256;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;autophagy of mitochondrion#GO:0000422;cellular process#GO:0009987;organelle disassembly#GO:1903008;process utilizing autophagic mechanism#GO:0061919;cellular component organization or biogenesis#GO:0071840;endosome organization#GO:0007032;cellular component disassembly#GO:0022411;organelle organization#GO:0006996;catabolic process#GO:0009056;vesicle organization#GO:0016050;mitochondrion organization#GO:0007005;autophagy#GO:0006914;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;autophagosome#GO:0005776;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000023781.1|UniProtKB=H2Y184 H2Y184 LOC100183278 PTHR18916:SF85 DYNACTIN 1-RELATED MICROTUBULE-BINDING TUBULIN-FOLDING COFACTOR B cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;microtubule plus-end binding#GO:0051010;binding#GO:0005488 cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;microtubule cytoskeleton organization#GO:0000226;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cellular process#GO:0009987;cytoplasmic microtubule organization#GO:0031122 supramolecular complex#GO:0099080;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;microtubule plus-end#GO:0035371;microtubule#GO:0005874 chaperone#PC00072 CIOIN|Ensembl=ENSCING00000023749.1|UniProtKB=H2XKA1 H2XKA1 PTHR11193:SF0 SMALL NUCLEAR RIBONUCLEOPROTEIN E SMALL NUCLEAR RIBONUCLEOPROTEIN E cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;RNA processing#GO:0006396;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;protein-RNA complex assembly#GO:0022618;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;spliceosomal snRNP assembly#GO:0000387;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;protein-containing complex organization#GO:0043933;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;ribonucleoprotein complex biogenesis#GO:0022613;mRNA processing#GO:0006397;protein-RNA complex organization#GO:0071826;RNA splicing, via transesterification reactions#GO:0000375 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;U4/U6 x U5 tri-snRNP complex#GO:0046540;U1 snRNP#GO:0005685;cellular anatomical entity#GO:0110165;organelle#GO:0043226;U4 snRNP#GO:0005687;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;U5 snRNP#GO:0005682;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;spliceosomal snRNP complex#GO:0097525;small nuclear ribonucleoprotein complex#GO:0030532;pICln-Sm protein complex#GO:0034715;protein-containing complex#GO:0032991;U2 snRNP#GO:0005686;spliceosomal tri-snRNP complex#GO:0097526;precatalytic spliceosome#GO:0071011;membrane-bounded organelle#GO:0043227;Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513 RNA splicing factor#PC00148;RNA processing factor#PC00147;RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000013078.2|UniProtKB=F6XWD7 F6XWD7 PTHR22906:SF48 PROPERDIN THROMBOSPONDIN TYPE 1 DOMAIN PROTEIN CIOIN|Ensembl=ENSCING00000021601.1|UniProtKB=H2XSL2 H2XSL2 deltex PTHR12622:SF4 DELTEX-RELATED PROTEIN DELTEX transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein ubiquitination#GO:0016567;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cell communication#GO:0007154;cellular process#GO:0009987;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;nitrogen compound metabolic process#GO:0006807;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;signaling#GO:0023052;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;Notch signaling pathway#GO:0007219 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000014220.2|UniProtKB=F6Y0Y2 F6Y0Y2 PTHR24419:SF34 INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASE PROTEIN TUBE-RELATED histone modifying activity#GO:0140993;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;mitotic cell cycle#GO:0000278;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell cycle#GO:0007049;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;signaling#GO:0023052 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 Toll pathway-drosophila#P06217>PLL#P06338 CIOIN|Ensembl=ENSCING00000008348.3|UniProtKB=F7B418 F7B418 PTHR16950:SF25 ZINC TRANSPORTER SLC39A7 HISTIDINE-RICH MEMBRANE PROTEIN KE4 ZINC TRANSPORTER SLC39A7 inorganic molecular entity transmembrane transporter activity#GO:0015318;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;inorganic cation transmembrane transporter activity#GO:0022890;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075 inorganic ion homeostasis#GO:0098771;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;homeostatic process#GO:0042592;inorganic ion transmembrane transport#GO:0098660;chemical homeostasis#GO:0048878;cellular process#GO:0009987;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;monoatomic ion homeostasis#GO:0050801;localization#GO:0051179;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation transport#GO:0006812;transition metal ion transport#GO:0000041;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655 primary active transporter#PC00068;transporter#PC00227 CIOIN|Ensembl=ENSCING00000000739.3|UniProtKB=Q1RL48 Q1RL48 Ci-ZF(ZZ)-7 PTHR24202:SF53 E3 UBIQUITIN-PROTEIN LIGASE MIB2 E3 UBIQUITIN-PROTEIN LIGASE MIB1 protein ubiquitination#GO:0016567;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;transport#GO:0006810;endocytosis#GO:0006897;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;vesicle-mediated transport#GO:0016192;cell communication#GO:0007154;cellular process#GO:0009987;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;localization#GO:0051179;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;import into cell#GO:0098657;signaling#GO:0023052;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;Notch signaling pathway#GO:0007219 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000019392.1|UniProtKB=H2Y1F5 H2Y1F5 PTHR19143:SF459 FIBRINOGEN/TENASCIN/ANGIOPOEITIN FIBRINOGEN C-TERMINAL DOMAIN-CONTAINING PROTEIN external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 CIOIN|Ensembl=ENSCING00000012432.2|UniProtKB=F6VIC3 F6VIC3 LOC100181593 PTHR10809:SF6 VESICLE-ASSOCIATED MEMBRANE PROTEIN-ASSOCIATED PROTEIN AT11025P-RELATED localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organelle localization#GO:0051640;endoplasmic reticulum organization#GO:0007029;membrane organization#GO:0061024;organelle organization#GO:0006996;endomembrane system organization#GO:0010256;cellular component organization#GO:0016043;cellular process#GO:0009987 intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;plasma membrane#GO:0005886;endoplasmic reticulum membrane#GO:0005789 membrane trafficking regulatory protein#PC00151 CIOIN|Ensembl=ENSCING00000006626.3|UniProtKB=F6UP98 F6UP98 LOC100187200 PTHR10997:SF7 IMPORTIN-7, 8, 11 IMPORTIN-11 cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;protein localization to nucleus#GO:0034504;nitrogen compound transport#GO:0071705;establishment of protein localization to organelle#GO:0072594;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;protein import into nucleus#GO:0006606;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;protein localization to organelle#GO:0033365;intracellular transport#GO:0046907;nuclear transport#GO:0051169;import into nucleus#GO:0051170 envelope#GO:0031975;cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear envelope#GO:0005635;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transporter#PC00227 CIOIN|Ensembl=ENSCING00000005903.3|UniProtKB=F6ZI41 F6ZI41 LOC100185251 PTHR24300:SF397 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 2U1 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;tetrapyrrole binding#GO:0046906;steroid hydroxylase activity#GO:0008395;oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497;heme binding#GO:0020037 response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;response to chemical#GO:0042221;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 oxygenase#PC00177;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000003455.3|UniProtKB=F6UAX7 F6UAX7 LOC100175452 PTHR23139:SF9 RNA-BINDING PROTEIN SPLICING FACTOR U2AF 65 KDA SUBUNIT nucleic acid binding#GO:0003676;single-stranded RNA binding#GO:0003727;RNA binding#GO:0003723;pre-mRNA binding#GO:0036002;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;RNA processing#GO:0006396;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;protein-RNA complex assembly#GO:0022618;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;protein-containing complex organization#GO:0043933;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;ribonucleoprotein complex biogenesis#GO:0022613;mRNA processing#GO:0006397;protein-RNA complex organization#GO:0071826;RNA splicing, via transesterification reactions#GO:0000375;spliceosomal complex assembly#GO:0000245 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;U2-type spliceosomal complex#GO:0005684;nuclear speck#GO:0016607;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear body#GO:0016604;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;U2-type prespliceosome#GO:0071004;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 CIOIN|Ensembl=ENSCING00000012052.2|UniProtKB=F6Z103 F6Z103 PTHR42683:SF87 ALDEHYDE REDUCTASE ALCOHOL DEHYDROGENASE-LIKE ISOFORM X1 oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 organic hydroxy compound metabolic process#GO:1901615;alcohol metabolic process#GO:0006066;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000005235.3|UniProtKB=F6W872 F6W872 PTHR45624:SF10 MITOCHONDRIAL BASIC AMINO ACIDS TRANSPORTER-RELATED SLC (SOLUTE CARRIER) HOMOLOG transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 localization#GO:0051179;establishment of localization#GO:0051234;transport#GO:0006810 transporter#PC00227 CIOIN|Ensembl=ENSCING00000007523.3|UniProtKB=F6TWS7 F6TWS7 PTHR14437:SF2 TRANSMEMBRANE PROTEIN 168 TRANSMEMBRANE PROTEIN 168 CIOIN|Ensembl=ENSCING00000013835.2|UniProtKB=F6QL93 F6QL93 PTHR10985:SF77 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, HES-RELATED GH26014P sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of multicellular organismal process#GO:0051239;regulation of cell development#GO:0060284;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regionalization#GO:0003002;developmental process#GO:0032502;multicellular organism development#GO:0007275;regulation of RNA biosynthetic process#GO:2001141;regulation of multicellular organismal development#GO:2000026;regulation of cell differentiation#GO:0045595;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of neurogenesis#GO:0050767;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;regulation of nervous system development#GO:0051960;biological regulation#GO:0065007;anterior/posterior pattern specification#GO:0009952;multicellular organismal process#GO:0032501;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;pattern specification process#GO:0007389;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;basic helix-loop-helix transcription factor#PC00055 CIOIN|Ensembl=ENSCING00000021425.1|UniProtKB=H2XLK8 H2XLK8 LOC100182196 PTHR19300:SF61 BETA-1,4-GALACTOSYLTRANSFERASE BETA-1,4-N-ACETYLGALACTOSAMINYLTRANSFERASE galactosyltransferase activity#GO:0008378;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 glycosylation#GO:0070085;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000001867.1|UniProtKB=F6T6F5 F6T6F5 LOC100176247 PTHR12391:SF0 ARP2/3 COMPLEX 21 KD SUBUNIT ACTIN-RELATED PROTEIN 2_3 COMPLEX SUBUNIT 3 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;Arp2/3 complex-mediated actin nucleation#GO:0034314;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;Arp2/3 protein complex#GO:0005885;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 Integrin signalling pathway#P00034>Arp2/3#P00912;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Arp2/3#P00876;Cytoskeletal regulation by Rho GTPase#P00016>ARP2/3#P00511 CIOIN|Ensembl=ENSCING00000015045.2|UniProtKB=F6X4W9 F6X4W9 PTHR43511:SF4 FAMILY NOT NAMED UTP--GLUCOSE-1-PHOSPHATE URIDYLYLTRANSFERASE CIOIN|Ensembl=ENSCING00000002541.3|UniProtKB=F6XQY6 F6XQY6 PTHR11929:SF145 ALPHA- 1,3 -FUCOSYLTRANSFERASE ALPHA-(1,3)-FUCOSYLTRANSFERASE FUT-1 transferase activity#GO:0016740;fucosyltransferase activity#GO:0008417;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 glycosylation#GO:0070085;metabolic process#GO:0008152 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000014942.2|UniProtKB=F6Y6N3 F6Y6N3 PTHR45993:SF6 B-CELL LYMPHOMA/LEUKEMIA 11 C2H2-TYPE DOMAIN-CONTAINING PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 CIOIN|Ensembl=ENSCING00000022223.1|UniProtKB=Q4H2V9 Q4H2V9 Ci-RelA PTHR24169:SF25 NUCLEAR FACTOR NF-KAPPA-B PROTEIN DORSAL-RELATED IMMUNITY FACTOR DIF-RELATED DNA-binding transcription factor#PC00218;Rel homology transcription factor#PC00252;immunoglobulin fold transcription factor#PC00251 Toll pathway-drosophila#P06217>DL#P06344;Toll receptor signaling pathway#P00054>NFkappaB#P01354 CIOIN|Ensembl=ENSCING00000020337.1|UniProtKB=H2XMN4 H2XMN4 LOC100178517 PTHR10844:SF19 CAVEOLIN CAVEOLIN-2 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;membrane assembly#GO:0071709;membrane organization#GO:0061024;plasma membrane organization#GO:0007009;endomembrane system organization#GO:0010256;cellular component organization#GO:0016043;cellular process#GO:0009987 plasma membrane raft#GO:0044853;caveola#GO:0005901;plasma membrane region#GO:0098590;membrane raft#GO:0045121;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;membrane microdomain#GO:0098857;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000005733.3|UniProtKB=F6U1Z9 F6U1Z9 LOC100180314 PTHR43157:SF31 PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN-RELATED PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000005502.3|UniProtKB=F7BD94 F7BD94 PTHR15598:SF5 ENHANCER OF MRNA-DECAPPING PROTEIN 4 ENHANCER OF MRNA-DECAPPING PROTEIN 4 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;heterocycle catabolic process#GO:0046700;RNA metabolic process#GO:0016070;nucleobase-containing compound metabolic process#GO:0006139;cellular nitrogen compound catabolic process#GO:0044270;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;RNA decapping#GO:0110154;organic cyclic compound metabolic process#GO:1901360;mRNA catabolic process#GO:0006402;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;organic substance catabolic process#GO:1901575;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;negative regulation of biosynthetic process#GO:0009890;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;nuclear-transcribed mRNA catabolic process#GO:0000956;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;nucleobase-containing compound catabolic process#GO:0034655;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;P-body#GO:0000932;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464;intracellular anatomical structure#GO:0005622 RNA processing factor#PC00147;RNA metabolism protein#PC00031;mRNA capping factor#PC00145 CIOIN|Ensembl=ENSCING00000003720.3|UniProtKB=F6WUN4 F6WUN4 LOC100175766 PTHR10671:SF108 EPITHELIAL MEMBRANE PROTEIN-RELATED CLAUDIN FAMILY PROTEIN-RELATED cytoskeletal protein#PC00085 CIOIN|Ensembl=ENSCING00000015912.2|UniProtKB=F6YZB7 F6YZB7 LOC100179623 PTHR10131:SF153 TNF RECEPTOR ASSOCIATED FACTOR RING-TYPE DOMAIN-CONTAINING PROTEIN protein binding#GO:0005515;binding#GO:0005488;tumor necrosis factor receptor binding#GO:0005164;signaling receptor binding#GO:0005102;tumor necrosis factor receptor superfamily binding#GO:0032813;cytokine receptor binding#GO:0005126 regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;regulation of canonical NF-kappaB signal transduction#GO:0043122;regulation of signaling#GO:0023051;biological regulation#GO:0065007;regulation of intracellular signal transduction#GO:1902531 receptor complex#GO:0043235;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;plasma membrane signaling receptor complex#GO:0098802;plasma membrane protein complex#GO:0098797;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;cytoplasmic side of plasma membrane#GO:0009898;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000014650.2|UniProtKB=F6V6D5 F6V6D5 PTHR45887:SF1 TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT EPSILON TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT EPSILON nucleoside-triphosphatase regulator activity#GO:0060589;nucleic acid binding#GO:0003676;translation initiation factor binding#GO:0031369;translation regulator activity#GO:0045182;GTPase regulator activity#GO:0030695;binding#GO:0005488;organic cyclic compound binding#GO:0097159;molecular function regulator activity#GO:0098772;translation initiation factor activity#GO:0003743;protein binding#GO:0005515;translation regulator activity, nucleic acid binding#GO:0090079;enzyme regulator activity#GO:0030234;translation factor activity, RNA binding#GO:0008135;guanyl-nucleotide exchange factor activity#GO:0005085 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622 translation initiation factor#PC00224;translation factor#PC00223;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000013012.2|UniProtKB=F6UH59 F6UH59 LOC100182272 PTHR10426:SF88 STRICTOSIDINE SYNTHASE-RELATED ADIPOCYTE PLASMA MEMBRANE-ASSOCIATED PROTEIN HEMOMUCIN-RELATED hydrolase activity#GO:0016787;catalytic activity#GO:0003824 CIOIN|Ensembl=ENSCING00000001025.3|UniProtKB=F6W0S4 F6W0S4 LOC100177825 PTHR10846:SF8 SODIUM/POTASSIUM/CALCIUM EXCHANGER INNER MEMBRANE PROTEIN YRBG calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;antiporter activity#GO:0015297;calcium channel activity#GO:0005262;potassium ion transmembrane transporter activity#GO:0015079;sodium ion transmembrane transporter activity#GO:0015081;monoatomic cation transmembrane transporter activity#GO:0008324;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;channel activity#GO:0015267;secondary active transmembrane transporter activity#GO:0015291;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;active monoatomic ion transmembrane transporter activity#GO:0022853;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;calcium ion transmembrane transport#GO:0070588;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;homeostatic process#GO:0042592;monoatomic cation homeostasis#GO:0055080;inorganic ion transmembrane transport#GO:0098660;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;cellular process#GO:0009987;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;calcium ion transport#GO:0006816;monoatomic ion homeostasis#GO:0050801;localization#GO:0051179;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation transport#GO:0006812;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000007560.3|UniProtKB=F6T886 F6T886 LOC100182838 PTHR46120:SF4 BETAINE--HOMOCYSTEINE S-METHYLTRANSFERASE 1 HCY-BINDING DOMAIN-CONTAINING PROTEIN methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824 organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;proteinogenic amino acid metabolic process#GO:0170039;sulfur compound metabolic process#GO:0006790;proteinogenic amino acid biosynthetic process#GO:0170038;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;aspartate family amino acid biosynthetic process#GO:0009067;alpha-amino acid biosynthetic process#GO:1901607;nitrogen compound metabolic process#GO:0006807;amino acid biosynthetic process#GO:0008652;alpha-amino acid metabolic process#GO:1901605;aspartate family amino acid metabolic process#GO:0009066;small molecule biosynthetic process#GO:0044283;L-amino acid biosynthetic process#GO:0170034;carboxylic acid metabolic process#GO:0019752;L-amino acid metabolic process#GO:0170033;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 methyltransferase#PC00155;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000000417.3|UniProtKB=F7BL63 F7BL63 LOC100182710 PTHR15127:SF32 HEAVYWEIGHT, ISOFORM A HEAVYWEIGHT, ISOFORM A protein binding#GO:0005515;binding#GO:0005488 CIOIN|Ensembl=ENSCING00000003014.3|UniProtKB=F6QAG3 F6QAG3 LOC100183290 PTHR13399:SF2 TRANSLOCON-ASSOCIATED PROTEIN TRAP , GAMMA SUBUNIT TRANSLOCON-ASSOCIATED PROTEIN SUBUNIT GAMMA cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000023501.1|UniProtKB=H2XWM7 H2XWM7 zf(tim10_ddp)-1 PTHR13172:SF0 MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM9B MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM10 B envelope#GO:0031975;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;transporter complex#GO:1990351;intracellular organelle lumen#GO:0070013;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;mitochondrial intermembrane space#GO:0005758;mitochondrial protein-containing complex#GO:0098798 primary active transporter#PC00068;transporter#PC00227 CIOIN|Ensembl=ENSCING00000003888.3|UniProtKB=F6TAK3 F6TAK3 PTHR12537:SF12 RNA BINDING PROTEIN PUMILIO-RELATED MATERNAL PROTEIN PUMILIO nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of biosynthetic process#GO:0009889;regulation of cellular process#GO:0050794;post-transcriptional regulation of gene expression#GO:0010608;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000008157.3|UniProtKB=Q4H2N1 Q4H2N1 Ci-USF PTHR46117:SF3 FI24210P1 FI24210P1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 basic helix-loop-helix transcription factor#PC00055 CIOIN|Ensembl=ENSCING00000020363.1|UniProtKB=H2XZY7 H2XZY7 LOC100176948 PTHR45615:SF40 MYOSIN HEAVY CHAIN, NON-MUSCLE MYOSIN HEAVY CHAIN, NON-MUSCLE microfilament motor activity#GO:0000146;cytoskeletal protein binding#GO:0008092;ATP-dependent activity#GO:0140657;binding#GO:0005488;actin filament binding#GO:0051015;cytoskeletal motor activity#GO:0003774;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779 supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;supramolecular fiber#GO:0099512;supramolecular polymer#GO:0099081;myosin complex#GO:0016459;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Myosin#P00867;Cytoskeletal regulation by Rho GTPase#P00016>Myosin#P00522;Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 CIOIN|Ensembl=ENSCING00000016854.2|UniProtKB=F7BJP4 F7BJP4 PTHR12137:SF54 CARBOHYDRATE SULFOTRANSFERASE CARBOHYDRATE SULFOTRANSFERASE sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824 transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000022389.1|UniProtKB=H2XT72 H2XT72 PTHR15045:SF1 FUCOSE-1-PHOSPHATE GUANYLYLTRANSFERASE FUCOSE-1-PHOSPHATE GUANYLYLTRANSFERASE transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000009610.3|UniProtKB=F7ADD0 F7ADD0 PTHR48020:SF12 PROTON MYO-INOSITOL COTRANSPORTER PROTON MYO-INOSITOL COTRANSPORTER transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 localization#GO:0051179;establishment of localization#GO:0051234;cellular process#GO:0009987;transmembrane transport#GO:0055085;transport#GO:0006810 cellular anatomical entity#GO:0110165;membrane#GO:0016020 transporter#PC00227 CIOIN|Ensembl=ENSCING00000007665.3|UniProtKB=F6T7L2 F6T7L2 LOC100186300 PTHR10697:SF1 MAMMALIAN EPENDYMIN-RELATED PROTEIN 1 MAMMALIAN EPENDYMIN-RELATED PROTEIN 1 cytoplasm#GO:0005737;lysosome#GO:0005764;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;lytic vacuole#GO:0000323;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000009445.3|UniProtKB=F7BHA0 F7BHA0 LOC100186609 PTHR19375:SF144 HEAT SHOCK PROTEIN 70KDA ENDOPLASMIC RETICULUM CHAPERONE BIP signal transduction#GO:0007165;endoplasmic reticulum unfolded protein response#GO:0030968;protein catabolic process#GO:0030163;organonitrogen compound catabolic process#GO:1901565;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;response to unfolded protein#GO:0006986;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;protein metabolic process#GO:0019538;signaling#GO:0023052;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;response to organic substance#GO:0010033;macromolecule catabolic process#GO:0009057;cellular response to stimulus#GO:0051716;response to endoplasmic reticulum stress#GO:0034976;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;ERAD pathway#GO:0036503;cell communication#GO:0007154;response to organonitrogen compound#GO:0010243;cellular process#GO:0009987;cellular response to topologically incorrect protein#GO:0035967;primary metabolic process#GO:0044238;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;response to topologically incorrect protein#GO:0035966;cellular response to unfolded protein#GO:0034620;biological regulation#GO:0065007;cellular response to stress#GO:0033554 membrane-enclosed lumen#GO:0031974;endoplasmic reticulum protein-containing complex#GO:0140534;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endoplasmic reticulum lumen#GO:0005788;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783 Hsp70 family chaperone#PC00027 Parkinson disease#P00049>Hsp70#P01208;Apoptosis signaling pathway#P00006>HSP70#P00321 CIOIN|Ensembl=ENSCING00000008686.3|UniProtKB=F6XMA0 F6XMA0 LOC100176488 PTHR11353:SF26 CHAPERONIN T-COMPLEX PROTEIN 1 SUBUNIT DELTA protein binding#GO:0005515;unfolded protein binding#GO:0051082;binding#GO:0005488 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein folding#GO:0006457;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 chaperonin#PC00073 CIOIN|Ensembl=ENSCING00000009729.3|UniProtKB=F6TIT1 F6TIT1 LOC100184829 PTHR12290:SF19 CORNICHON-RELATED PROTEIN CORNICHON HOMOLOG 4 localization#GO:0051179;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;establishment of localization#GO:0051234;transport#GO:0006810;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193 COPII-coated ER to Golgi transport vesicle#GO:0030134;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;coated vesicle#GO:0030135;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 membrane traffic protein#PC00150 CIOIN|Ensembl=ENSCING00000016071.2|UniProtKB=F6VES6 F6VES6 LOC100176647 PTHR10924:SF4 MAJOR FACILITATOR SUPERFAMILY PROTEIN-RELATED GH15861P tetrapyrrole binding#GO:0046906;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;binding#GO:0005488;organic cyclic compound binding#GO:0097159;heme binding#GO:0020037 localization#GO:0051179;organic substance transport#GO:0071702;metal ion transport#GO:0030001;establishment of localization#GO:0051234;transport#GO:0006810;monoatomic cation transport#GO:0006812;nitrogen compound transport#GO:0071705;iron ion transport#GO:0006826;transition metal ion transport#GO:0000041;monoatomic ion transport#GO:0006811 cellular anatomical entity#GO:0110165;membrane#GO:0016020 secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000008000.3|UniProtKB=F6TEN3 F6TEN3 PTHR43763:SF6 XAA-PRO AMINOPEPTIDASE 1 XAA-PRO AMINOPEPTIDASE 1 protease#PC00190 CIOIN|Ensembl=ENSCING00000000060.2|UniProtKB=F6V750 F6V750 LOC100179802 PTHR24024:SF19 PULMONARY SURFACTANT-ASSOCIATED PROTEIN A FARMER, ISOFORM H extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 surfactant#PC00212;structural protein#PC00211 CIOIN|Ensembl=ENSCING00000014923.2|UniProtKB=F6Y782 F6Y782 LOC100185842 PTHR43385:SF1 RIBOFLAVIN TRANSPORTER RIBJ RIBOFLAVIN TRANSPORTER RIBJ transporter#PC00227 CIOIN|Ensembl=ENSCING00000002148.3|UniProtKB=F6SM91 F6SM91 PTHR24039:SF58 FIBRILLIN-RELATED EGF-LIKE DOMAIN-CONTAINING PROTEIN extracellular matrix structural protein#PC00103 CIOIN|Ensembl=ENSCING00000013736.2|UniProtKB=F6RRB1 F6RRB1 PTHR12675:SF12 MUSCLEBLIND-LIKE PROTEIN PROTEIN MUSCLEBLIND nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nitrogen compound metabolic process#GO:0051171;regulation of biosynthetic process#GO:0009889;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA metabolic process#GO:0051252;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 RNA splicing factor#PC00148;RNA processing factor#PC00147;RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000009049.3|UniProtKB=F6R6J0 F6R6J0 PTHR46208:SF1 MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM70 MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM70 primary active transporter#PC00068;transporter#PC00227 CIOIN|Ensembl=ENSCING00000024543.1|UniProtKB=H2Y1N3 H2Y1N3 PTHR11119:SF3 XANTHINE-URACIL / VITAMIN C PERMEASE FAMILY MEMBER LD30822P transporter#PC00227 CIOIN|Ensembl=ENSCING00000008372.3|UniProtKB=F7A1H6 F7A1H6 LOC100183351 PTHR10778:SF8 SOLUTE CARRIER FAMILY 35 MEMBER B ADENOSINE 3'-PHOSPHO 5'-PHOSPHOSULFATE TRANSPORTER 2 carbohydrate derivative transmembrane transporter activity#GO:1901505;purine nucleotide transmembrane transporter activity#GO:0015216;nucleobase-containing compound transmembrane transporter activity#GO:0015932;transmembrane transporter activity#GO:0022857;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215 localization#GO:0051179;organic substance transport#GO:0071702;organophosphate ester transport#GO:0015748;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;organic anion transport#GO:0015711;nucleobase-containing compound transport#GO:0015931;transport#GO:0006810;nitrogen compound transport#GO:0071705;cellular process#GO:0009987;carbohydrate derivative transport#GO:1901264 bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;Golgi membrane#GO:0000139;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000006470.3|UniProtKB=F6Q539 F6Q539 PTHR12358:SF111 SPHINGOSINE KINASE CERAMIDE KINASE, ISOFORM A transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;lipid kinase activity#GO:0001727 lipid metabolic process#GO:0006629;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular process#GO:0009987;sphingolipid metabolic process#GO:0006665;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;ceramide metabolic process#GO:0006672;primary metabolic process#GO:0044238;membrane lipid metabolic process#GO:0006643;nitrogen compound metabolic process#GO:0006807;phosphorylation#GO:0016310;cellular lipid metabolic process#GO:0044255;amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 kinase#PC00137 CIOIN|Ensembl=ENSCING00000016761.2|UniProtKB=F6QYL2 F6QYL2 LOC100181387 PTHR17901:SF14 MAGNESIUM-DEPENDENT PHOSPHATASE 1 MDP1 MAGNESIUM-DEPENDENT PHOSPHATASE 1 hydrolase#PC00121;phosphatase#PC00181 CIOIN|Ensembl=ENSCING00000012445.2|UniProtKB=F6UUU5 F6UUU5 PTHR11537:SF113 VOLTAGE-GATED POTASSIUM CHANNEL POTASSIUM VOLTAGE-GATED CHANNEL PROTEIN SHAKER monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;delayed rectifier potassium channel activity#GO:0005251;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated potassium channel activity#GO:0005249;transporter activity#GO:0005215;channel activity#GO:0015267;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;regulation of membrane potential#GO:0042391;action potential#GO:0001508;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;localization#GO:0051179;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;monoatomic cation transport#GO:0006812;potassium ion transmembrane transport#GO:0071805;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;potassium ion transport#GO:0006813 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;voltage-gated potassium channel complex#GO:0008076;cation channel complex#GO:0034703;plasma membrane#GO:0005886 transporter#PC00227;voltage-gated ion channel#PC00241 CIOIN|Ensembl=ENSCING00000005748.3|UniProtKB=F6PZ06 F6PZ06 LOC100185096 PTHR23073:SF13 26S PROTEASOME REGULATORY SUBUNIT 26S PROTEASOME REGULATORY SUBUNIT 7 ATP-dependent activity#GO:0140657 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 peptidase complex#GO:1905368;protein-containing complex#GO:0032991;proteasome accessory complex#GO:0022624;proteasome regulatory particle#GO:0005838;catalytic complex#GO:1902494;proteasome complex#GO:0000502;endopeptidase complex#GO:1905369;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 protease#PC00190;protein modifying enzyme#PC00260 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489 CIOIN|Ensembl=ENSCING00000003628.3|UniProtKB=F6U8D6 F6U8D6 LOC100177805 PTHR14659:SF1 ALPHA- AND GAMMA-ADAPTIN-BINDING PROTEIN P34 ALPHA- AND GAMMA-ADAPTIN-BINDING PROTEIN P34 CIOIN|Ensembl=ENSCING00000001343.3|UniProtKB=F6SXA9 F6SXA9 PTHR10267:SF0 DNA POLYMERASE SUBUNIT GAMMA-1 DNA POLYMERASE SUBUNIT GAMMA-1 hydrolase activity, acting on ester bonds#GO:0016788;DNA-directed DNA polymerase activity#GO:0003887;nuclease activity#GO:0004518;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;hydrolase activity#GO:0016787;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on DNA#GO:0140097;exonuclease activity#GO:0004527;3'-5' exonuclease activity#GO:0008408;DNA polymerase activity#GO:0034061 cellular aromatic compound metabolic process#GO:0006725;mitochondrial genome maintenance#GO:0000002;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;mitochondrial DNA metabolic process#GO:0032042;organelle organization#GO:0006996;nitrogen compound metabolic process#GO:0006807;DNA-templated DNA replication#GO:0006261;mitochondrion organization#GO:0007005;DNA replication#GO:0006260;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-directed DNA polymerase#PC00018 CIOIN|Ensembl=ENSCING00000011967.1|UniProtKB=F6SKC4 F6SKC4 PTHR46473:SF23 GH08155P GH08155P CIOIN|Ensembl=ENSCING00000007475.3|UniProtKB=A0A1W5B7P7 A0A1W5B7P7 LOC100185279 PTHR11766:SF0 TYROSYL-TRNA SYNTHETASE TYROSINE--TRNA LIGASE, MITOCHONDRIAL catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on RNA#GO:0140098;ligase activity#GO:0016874;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;tRNA metabolic process#GO:0006399;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 aminoacyl-tRNA synthetase#PC00047 CIOIN|Ensembl=ENSCING00000011480.2|UniProtKB=F6XI46 F6XI46 LOC100176530 PTHR24251:SF30 OVOCHYMASE-RELATED MEMBRANE FRIZZLED-RELATED PROTEIN serine protease#PC00203;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000022760.1|UniProtKB=H2XS68 H2XS68 PTHR45635:SF14 ADP,ATP CARRIER PROTEIN 1-RELATED-RELATED ADP_ATP TRANSLOCASE transfer/carrier protein#PC00219 CIOIN|Ensembl=ENSCING00000022199.1|UniProtKB=H2XVC8 H2XVC8 PTHR11214:SF283 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE N-ACETYLLACTOSAMINIDE BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE 4-LIKE transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;protein O-linked glycosylation#GO:0006493;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 bounding membrane of organelle#GO:0098588;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;Golgi membrane#GO:0000139;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111 CIOIN|Ensembl=ENSCING00000003849.3|UniProtKB=A0A1W2WE34 A0A1W2WE34 LOC100181108 PTHR36902:SF1 ENRICHED IN SURFACE-LABELED PROTEOME PROTEIN 9 ENRICHED IN SURFACE-LABELED PROTEOME PROTEIN 9 CIOIN|Ensembl=ENSCING00000002754.3|UniProtKB=F7AHQ4 F7AHQ4 LOC100185868 PTHR15627:SF8 NATURAL KILLER CELL-SPECIFIC ANTIGEN KLIP1 TRNA-URIDINE AMINOCARBOXYPROPYLTRANSFERASE 1 CIOIN|Ensembl=ENSCING00000000199.3|UniProtKB=F6WF92 F6WF92 LOC100176536 PTHR12312:SF16 TWISTED GASTRULATION PROTEIN HOMOLOG 1-A-RELATED TWISTED GASTRULATION PROTEIN HOMOLOG 1-A-RELATED regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of BMP signaling pathway#GO:0030510;regulation of cell communication#GO:0010646;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;regulation of signaling#GO:0023051;biological regulation#GO:0065007;regulation of cellular response to growth factor stimulus#GO:0090287 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 DPP signaling pathway#P06213>TSG#P06287;BMP/activin signaling pathway-drosophila#P06211>TSG#P06242;SCW signaling pathway#P06216>TSG#P06330;DPP-SCW signaling pathway#P06212>TSG#P06258 CIOIN|Ensembl=ENSCING00000007827.3|UniProtKB=F6XFA8 F6XFA8 LOC100176021 PTHR22624:SF49 CYSTEINE PROTEASE ATG4 CYSTEINE PROTEASE cysteine-type peptidase activity#GO:0008234;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197 microautophagy#GO:0016237;cellular component biogenesis#GO:0044085;macroautophagy#GO:0016236;macromolecule modification#GO:0043412;mitophagy#GO:0000423;protein modification process#GO:0036211;gene expression#GO:0010467;autophagy of mitochondrion#GO:0000422;biosynthetic process#GO:0009058;post-translational protein modification#GO:0043687;protein processing#GO:0016485;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;cellular component disassembly#GO:0022411;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;mitochondrion organization#GO:0007005;protein metabolic process#GO:0019538;protein lipidation#GO:0006497;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular component assembly#GO:0022607;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular component organization#GO:0016043;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organelle disassembly#GO:1903008;lipoprotein biosynthetic process#GO:0042158;primary metabolic process#GO:0044238;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;autophagosome assembly#GO:0000045;lipoprotein metabolic process#GO:0042157;autophagy#GO:0006914;piecemeal microautophagy of the nucleus#GO:0034727 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 cysteine protease#PC00081;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000023488.1|UniProtKB=H2Y3C0 H2Y3C0 PTHR11829:SF380 FORKHEAD BOX PROTEIN PROTEIN FORK HEAD sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;anatomical structure morphogenesis#GO:0009653;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 CIOIN|Ensembl=ENSCING00000000686.3|UniProtKB=F6QRZ2 F6QRZ2 PTHR22738:SF15 RASSF LD40758P regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000002866.2|UniProtKB=F6TMN3 F6TMN3 LOC100183592 PTHR10855:SF2 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 12/COP9 SIGNALOSOME COMPLEX SUBUNIT 4 COP9 SIGNALOSOME COMPLEX SUBUNIT 4 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;COP9 signalosome#GO:0008180;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622 protease#PC00190 CIOIN|Ensembl=ENSCING00000021059.1|UniProtKB=H2XLZ0 H2XLZ0 PTHR45893:SF3 POLYCOMB GROUP RING FINGER PROTEIN POLYCOMB GROUP RING FINGER PROTEIN 3 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;nuclear ubiquitin ligase complex#GO:0000152;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;PcG protein complex#GO:0031519;protein-containing complex#GO:0032991;PRC1 complex#GO:0035102;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 chromatin/chromatin-binding, or -regulatory protein#PC00077;histone modifying enzyme#PC00261 CIOIN|Ensembl=ENSCING00000009655.3|UniProtKB=F6WUQ7 F6WUQ7 PTHR10670:SF0 DNA POLYMERASE EPSILON CATALYTIC SUBUNIT A DNA POLYMERASE EPSILON CATALYTIC SUBUNIT A hydrolase activity, acting on ester bonds#GO:0016788;nucleic acid binding#GO:0003676;DNA-directed DNA polymerase activity#GO:0003887;DNA exonuclease activity, producing 5'-phosphomonoesters#GO:0016895;3'-5'-DNA exonuclease activity#GO:0008296;nuclease activity#GO:0004518;DNA exonuclease activity#GO:0004529;binding#GO:0005488;catalytic activity#GO:0003824;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters#GO:0016796;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring phosphorus-containing groups#GO:0016772;exonuclease activity#GO:0004527;transferase activity#GO:0016740;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;hydrolase activity#GO:0016787;catalytic activity, acting on DNA#GO:0140097;DNA nuclease activity#GO:0004536;3'-5' exonuclease activity#GO:0008408;DNA polymerase activity#GO:0034061 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;nucleotide-excision repair#GO:0006289;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;base-excision repair#GO:0006284;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;DNA damage response#GO:0006974;mitotic cell cycle#GO:0000278;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;DNA-templated DNA replication#GO:0006261;cell cycle#GO:0007049;cellular response to stress#GO:0033554;DNA replication#GO:0006260;metabolic process#GO:0008152;DNA strand elongation involved in DNA replication#GO:0006271;DNA metabolic process#GO:0006259;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;epsilon DNA polymerase complex#GO:0008622;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622;DNA polymerase complex#GO:0042575;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 DNA metabolism protein#PC00009 CIOIN|Ensembl=ENSCING00000000881.3|UniProtKB=F6UPL4 F6UPL4 PTHR10516:SF443 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FK506-BINDING PROTEIN 59-RELATED chaperone#PC00072 TGF-beta signaling pathway#P00052>FKBP12#P01288 CIOIN|Ensembl=ENSCING00000006310.3|UniProtKB=F6PQW3 F6PQW3 PTHR45725:SF1 FORMIN HOMOLOGY 2 FAMILY MEMBER DISHEVELLED ASSOCIATED ACTIVATOR OF MORPHOGENESIS, ISOFORM D Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 CIOIN|Ensembl=ENSCING00000014519.2|UniProtKB=H2XX27 H2XX27 LOC100177482 PTHR18875:SF8 SARCOMA ANTIGEN NY-SAR-24/CYTOSKELETAL PROTEIN SOJO COILED-COIL DOMAIN-CONTAINING PROTEIN 18 cytoskeletal protein#PC00085 CIOIN|Ensembl=ENSCING00000001497.3|UniProtKB=F6THG7 F6THG7 PTHR47456:SF6 PHD-TYPE DOMAIN-CONTAINING PROTEIN SI:DKEY-31C13.1 CIOIN|Ensembl=ENSCING00000005987.3|UniProtKB=F6VSX4 F6VSX4 PTHR11119:SF3 XANTHINE-URACIL / VITAMIN C PERMEASE FAMILY MEMBER LD30822P transporter#PC00227 CIOIN|Ensembl=ENSCING00000019704.1|UniProtKB=H2XT31 H2XT31 LOC101242218 PTHR43591:SF101 METHYLTRANSFERASE METHYLTRANSFERASE-LIKE PROTEIN 27 methyltransferase#PC00155;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000007454.3|UniProtKB=F6YJ10 F6YJ10 PTHR12898:SF1 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 24 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 24 molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;protein-macromolecule adaptor activity#GO:0030674 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of RNA metabolic process#GO:0051254;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;mediator complex#GO:0016592;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031;general transcription factor#PC00259 CIOIN|Ensembl=ENSCING00000003072.3|UniProtKB=L7N0R2 L7N0R2 PTHR19818:SF157 ZINC FINGER PROTEIN ZIC AND GLI C2H2-TYPE DOMAIN-CONTAINING PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 CIOIN|Ensembl=ENSCING00000021539.1|UniProtKB=A8WHA5 A8WHA5 clf-3 PTHR23389:SF6 CHROMOSOME TRANSMISSION FIDELITY FACTOR 18 REPLICATION FACTOR C SUBUNIT 1 DNA metabolism protein#PC00009 DNA replication#P00017>RFC#P00529 CIOIN|Ensembl=ENSCING00000005653.3|UniProtKB=F6Y1Y9 F6Y1Y9 PTHR45570:SF2 CARBOXYLIC ESTER HYDROLASE ACETYLCHOLINESTERASE 1-LIKE metabolite interconversion enzyme#PC00262;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000012556.2|UniProtKB=F7AAT5 F7AAT5 PTHR15909:SF0 39S RIBOSOMAL PROTEIN L35, MITOCHONDRIAL LARGE RIBOSOMAL SUBUNIT PROTEIN BL35M cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000012824.2|UniProtKB=F6W3D9 F6W3D9 PTHR11669:SF5 REPLICATION FACTOR C / DNA POLYMERASE III GAMMA-TAU SUBUNIT REPLICATION FACTOR C SUBUNIT 2 ATP-dependent activity, acting on DNA#GO:0008094;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on DNA#GO:0140097;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;response to stress#GO:0006950;nitrogen compound metabolic process#GO:0006807;DNA-templated DNA replication#GO:0006261;DNA replication#GO:0006260;cellular response to stress#GO:0033554;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;replication fork#GO:0005657 DNA-directed DNA polymerase#PC00018 DNA replication#P00017>RFC#P00529 CIOIN|Ensembl=ENSCING00000009052.3|UniProtKB=F6R2J6 F6R2J6 PTHR10352:SF25 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT G FOUND IN NEURONS, ISOFORM A-RELATED translation initiation factor#PC00224;translation factor#PC00223 CIOIN|Ensembl=ENSCING00000007956.3|UniProtKB=Q1RLI8 Q1RLI8 Ci-ZF(C2H2)-38 PTHR24404:SF111 ZINC FINGER PROTEIN GASTRULA ZINC FINGER PROTEIN XLCGF49.1-LIKE-RELATED sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 CIOIN|Ensembl=ENSCING00000011616.2|UniProtKB=F7AQV0 F7AQV0 PTHR13636:SF0 TRANSMEMBRANE PROTEIN 258 TRANSMEMBRANE PROTEIN 258 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226 CIOIN|Ensembl=ENSCING00000011786.2|UniProtKB=F6S909 F6S909 PTHR12560:SF0 LONGEVITY ASSURANCE FACTOR 1 LAG1 LD18904P transferase activity#GO:0016740;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity#GO:0003824;N-acyltransferase activity#GO:0016410 lipid metabolic process#GO:0006629;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;membrane lipid biosynthetic process#GO:0046467;sphingolipid metabolic process#GO:0006665;ceramide metabolic process#GO:0006672;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;membrane lipid metabolic process#GO:0006643;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;ceramide biosynthetic process#GO:0046513;cellular lipid metabolic process#GO:0044255;amide metabolic process#GO:0043603;sphingolipid biosynthetic process#GO:0030148;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000018708.1|UniProtKB=H2XXL6 H2XXL6 PTHR14928:SF16 MICRO-RNA BINDING ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 7 C3H1-TYPE DOMAIN-CONTAINING PROTEIN nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;RNA metabolic process#GO:0016070;regulatory ncRNA processing#GO:0070918;RNA processing#GO:0006396;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulatory ncRNA-mediated gene silencing#GO:0031047;miRNA processing#GO:0035196;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000014876.2|UniProtKB=F6ZA49 F6ZA49 LOC100175348 PTHR31699:SF1 NUDIX T16 FAMILY MEMBER U8 SNORNA-DECAPPING ENZYME snoRNA binding#GO:0030515;catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;nuclease activity#GO:0004518;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;endonuclease activity#GO:0004519;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity#GO:0016787;RNA nuclease activity#GO:0004540;RNA endonuclease activity#GO:0004521 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;heterocycle catabolic process#GO:0046700;RNA metabolic process#GO:0016070;nucleobase-containing compound metabolic process#GO:0006139;cellular nitrogen compound catabolic process#GO:0044270;regulation of biological process#GO:0050789;ncRNA metabolic process#GO:0034660;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;mRNA catabolic process#GO:0006402;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance catabolic process#GO:1901575;negative regulation of cellular process#GO:0048523;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;negative regulation of biosynthetic process#GO:0009890;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;nucleobase-containing compound catabolic process#GO:0034655;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000000272.3|UniProtKB=F6ZZZ6 F6ZZZ6 ci-zf(zz)-8 PTHR22870:SF398 REGULATOR OF CHROMOSOME CONDENSATION E3 UBIQUITIN-PROTEIN LIGASE HERC2 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 CIOIN|Ensembl=ENSCING00000024158.1|UniProtKB=H2XL08 H2XL08 PTHR15555:SF0 ZINC FINGER HIT DOMAIN CONTAINING PROTEIN 2 PROTEIN FON -RELATED ZINC FINGER HIT DOMAIN-CONTAINING PROTEIN 2 CIOIN|Ensembl=ENSCING00000005151.3|UniProtKB=H2XNA5 H2XNA5 PTHR23159:SF60 CENTROSOMAL PROTEIN 2 SPINDLE ASSEMBLY ABNORMAL PROTEIN 4 chromatin/chromatin-binding, or -regulatory protein#PC00077 CIOIN|Ensembl=ENSCING00000005241.3|UniProtKB=F6YH02 F6YH02 PTHR22588:SF3 VWFA DOMAIN-CONTAINING PROTEIN VWFA DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000014932.2|UniProtKB=F7AE79 F7AE79 PTHR21330:SF1 E3 SUMO-PROTEIN LIGASE NSE2 E3 SUMO-PROTEIN LIGASE NSE2 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;SUMO transferase activity#GO:0019789;SUMO ligase activity#GO:0061665;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;double-strand break repair#GO:0006302;macromolecule modification#GO:0043412;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;post-translational protein modification#GO:0043687;nucleobase-containing compound metabolic process#GO:0006139;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;recombinational repair#GO:0000725;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;protein sumoylation#GO:0016925;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;double-strand break repair via homologous recombination#GO:0000724;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;catalytic complex#GO:1902494;transferase complex#GO:1990234;condensed chromosome#GO:0000793;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000001536.3|UniProtKB=Q1RL33 Q1RL33 Ci-ZF(MYND)-12 PTHR46831:SF1 ZINC FINGER MYND DOMAIN-CONTAINING PROTEIN 19 ZINC FINGER MYND DOMAIN-CONTAINING PROTEIN 19 cytoplasm#GO:0005737;cell junction#GO:0030054;synapse#GO:0045202;cellular anatomical entity#GO:0110165;membrane#GO:0016020;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000014459.2|UniProtKB=F6YAR9 F6YAR9 PTHR12137:SF54 CARBOHYDRATE SULFOTRANSFERASE CARBOHYDRATE SULFOTRANSFERASE sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824 transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000021998.1|UniProtKB=H2XLK9 H2XLK9 LOC100183093 PTHR12817:SF0 TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 6B GEO08327P1 localization#GO:0051179;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;establishment of localization#GO:0051234;transport#GO:0006810;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193 trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231;vesicle tethering complex#GO:0099023;TRAPP complex#GO:0030008;Golgi apparatus#GO:0005794;organelle subcompartment#GO:0031984;intracellular protein-containing complex#GO:0140535;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cis-Golgi network#GO:0005801;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791 CIOIN|Ensembl=ENSCING00000014490.2|UniProtKB=F6X034 F6X034 PTHR48099:SF11 C-1-TETRAHYDROFOLATE SYNTHASE, CYTOPLASMIC-RELATED BIFUNCTIONAL METHYLENETETRAHYDROFOLATE DEHYDROGENASE_CYCLOHYDROLASE, MITOCHONDRIAL hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular modified amino acid metabolic process#GO:0006575;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;folic acid-containing compound metabolic process#GO:0006760;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262 Formyltetrahydrofolate biosynthesis#P02743>Methylene tetrahydrofolate dehydrogenase#P02952 CIOIN|Ensembl=ENSCING00000022937.1|UniProtKB=H2XWQ2 H2XWQ2 LOC100178793 PTHR13312:SF0 HIV-INDUCED PROTEIN-7-LIKE PROTEASE UBIQUITIN THIOESTERASE OTU1 cysteine-type peptidase activity#GO:0008234;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;cysteine-type deubiquitinase activity#GO:0004843 signal transduction#GO:0007165;endoplasmic reticulum unfolded protein response#GO:0030968;macromolecule modification#GO:0043412;protein catabolic process#GO:0030163;organonitrogen compound catabolic process#GO:1901565;protein modification process#GO:0036211;post-translational protein modification#GO:0043687;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;response to unfolded protein#GO:0006986;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;response to organic substance#GO:0010033;macromolecule catabolic process#GO:0009057;cellular response to stimulus#GO:0051716;response to endoplasmic reticulum stress#GO:0034976;cellular response to chemical stimulus#GO:0070887;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;cellular response to organic substance#GO:0071310;organonitrogen compound metabolic process#GO:1901564;cell communication#GO:0007154;ERAD pathway#GO:0036503;response to organonitrogen compound#GO:0010243;cellular process#GO:0009987;cellular response to topologically incorrect protein#GO:0035967;primary metabolic process#GO:0044238;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cellular response to unfolded protein#GO:0034620;response to topologically incorrect protein#GO:0035966;protein modification by small protein removal#GO:0070646;biological regulation#GO:0065007;protein deubiquitination#GO:0016579;cellular response to stress#GO:0033554 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cysteine protease#PC00081;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000008276.3|UniProtKB=F6QHP8 F6QHP8 PTHR11525:SF0 FARNESYL-PYROPHOSPHATE SYNTHETASE FARNESYL PYROPHOSPHATE SYNTHASE prenyltransferase activity#GO:0004659;transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;phospholipid biosynthetic process#GO:0008654;organophosphate biosynthetic process#GO:0090407;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;phospholipid metabolic process#GO:0006644;lipid biosynthetic process#GO:0008610;isoprenoid metabolic process#GO:0006720;phosphorus metabolic process#GO:0006793;isoprenoid biosynthetic process#GO:0008299;phosphate-containing compound metabolic process#GO:0006796;primary metabolic process#GO:0044238;terpenoid biosynthetic process#GO:0016114;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;terpenoid metabolic process#GO:0006721;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 acyltransferase#PC00042;metabolite interconversion enzyme#PC00262 Cholesterol biosynthesis#P00014>Geranyl trans-transferase#P00493 CIOIN|Ensembl=ENSCING00000022173.1|UniProtKB=H2XZ04 H2XZ04 PTHR11709:SF394 MULTI-COPPER OXIDASE FI03373P-RELATED oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 oxidase#PC00175;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000019824.1|UniProtKB=H2Y315 H2Y315 LOC113474371 PTHR12920:SF4 RYBP AND YAF2-RELATED GEO03726P1 molecular adaptor activity#GO:0060090;nucleic acid binding#GO:0003676;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;binding#GO:0005488;organic cyclic compound binding#GO:0097159;protein-macromolecule adaptor activity#GO:0030674;DNA binding#GO:0003677 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transcription cofactor#PC00217 CIOIN|Ensembl=ENSCING00000000509.3|UniProtKB=F6VQ18 F6VQ18 LOC100175413 PTHR19444:SF13 UNC-93 RELATED PROTEIN UNC-93 HOMOLOG A membrane-bound signaling molecule#PC00152 CIOIN|Ensembl=ENSCING00000010057.3|UniProtKB=F6QH02 F6QH02 PTHR23098:SF16 AGAP001331-PA-RELATED REGULATORY PROTEIN ZESTE membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000005679.3|UniProtKB=F6XD13 F6XD13 LOC100175924 PTHR34707:SF1 VIMENTIN-TYPE INTERMEDIATE FILAMENT-ASSOCIATED COILED-COIL PROTEIN VIMENTIN-TYPE INTERMEDIATE FILAMENT-ASSOCIATED COILED-COIL PROTEIN CIOIN|Ensembl=ENSCING00000000033.3|UniProtKB=F6VVP4 F6VVP4 PTHR10044:SF139 INHIBITOR OF APOPTOSIS DEATH-ASSOCIATED INHIBITOR OF APOPTOSIS 2 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protease inhibitor#PC00191 CIOIN|Ensembl=ENSCING00000004109.3|UniProtKB=C4B8X1 C4B8X1 Ci-ARM37 PTHR15599:SF1 RTDR1 RADIAL SPOKE HEAD 14 HOMOLOG CIOIN|Ensembl=ENSCING00000012632.2|UniProtKB=F6XDJ2 F6XDJ2 PTHR24089:SF59 SOLUTE CARRIER FAMILY 25 MITOCHONDRIAL THIAMINE PYROPHOSPHATE CARRIER transmembrane transporter activity#GO:0022857;organic cation transmembrane transporter activity#GO:0015101;transporter activity#GO:0005215 localization#GO:0051179;organic substance transport#GO:0071702;quaternary ammonium group transport#GO:0015697;organophosphate ester transport#GO:0015748;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;organic anion transport#GO:0015711;organic cation transport#GO:0015695;transport#GO:0006810;vitamin transport#GO:0051180;nitrogen compound transport#GO:0071705;cellular process#GO:0009987 envelope#GO:0031975;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;organelle membrane#GO:0031090;organelle inner membrane#GO:0019866;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227 mitochondrial carrier protein#PC00158;secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000014676.2|UniProtKB=F6ZW39 F6ZW39 LOC100181037 PTHR13794:SF58 ENOLASE SUPERFAMILY, MANDELATE RACEMASE MITOCHONDRIAL ENOLASE SUPERFAMILY MEMBER 1 cation binding#GO:0043169;carbon-oxygen lyase activity#GO:0016835;magnesium ion binding#GO:0000287;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;hydro-lyase activity#GO:0016836;metal ion binding#GO:0046872;lyase activity#GO:0016829;ion binding#GO:0043167 carbohydrate catabolic process#GO:0016052;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carbohydrate metabolic process#GO:0005975;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;primary metabolic process#GO:0044238 epimerase/racemase#PC00096;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000023176.1|UniProtKB=H2Y2E4 H2Y2E4 PTHR21064:SF1 AMINOGLYCOSIDE PHOSPHOTRANSFERASE DOMAIN-CONTAINING PROTEIN-RELATED HYDROXYLYSINE KINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301 CIOIN|Ensembl=ENSCING00000024358.1|UniProtKB=H2Y197 H2Y197 LOC100179460 PTHR11599:SF6 PROTEASOME SUBUNIT ALPHA/BETA PROTEASOME SUBUNIT BETA TYPE-2 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;peptidase complex#GO:1905368;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;proteasome complex#GO:0000502;membrane-bounded organelle#GO:0043227;endopeptidase complex#GO:1905369;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protease#PC00190;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000006904.3|UniProtKB=F6YA95 F6YA95 LOC100176054 PTHR10536:SF0 DNA PRIMASE SMALL SUBUNIT DNA PRIMASE SMALL SUBUNIT catalytic activity, acting on RNA#GO:0140098;5'-3' RNA polymerase activity#GO:0034062;transferase activity#GO:0016740;DNA-directed 5'-3' RNA polymerase activity#GO:0003899;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;RNA polymerase activity#GO:0097747;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring phosphorus-containing groups#GO:0016772 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA biosynthetic process#GO:0032774;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nucleobase-containing compound biosynthetic process#GO:0034654;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;DNA-templated DNA replication#GO:0006261;aromatic compound biosynthetic process#GO:0019438;DNA replication#GO:0006260;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 primase#PC00189 DNA replication#P00017>Primase#P00528 CIOIN|Ensembl=ENSCING00000013038.2|UniProtKB=F6TT24 F6TT24 PTHR35442:SF1 TRANSMEMBRANE PROTEIN 249 CATION CHANNEL SPERM-ASSOCIATED AUXILIARY SUBUNIT TMEM249 CIOIN|Ensembl=ENSCING00000004818.3|UniProtKB=F6R955 F6R955 PTHR23048:SF1 MYOSIN LIGHT CHAIN 1, 3 MYOSIN LIGHT CHAIN 4 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;myosin complex#GO:0016459;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 CIOIN|Ensembl=ENSCING00000023193.1|UniProtKB=H2Y1C4 H2Y1C4 LOC100177059 PTHR12250:SF0 PHOSPHATIDYLINOSITOL GLYCAN, CLASS N GPI ETHANOLAMINE PHOSPHATE TRANSFERASE 1 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;phospholipid biosynthetic process#GO:0008654;macromolecule modification#GO:0043412;organophosphate biosynthetic process#GO:0090407;phosphatidylinositol biosynthetic process#GO:0006661;glycolipid metabolic process#GO:0006664;protein modification process#GO:0036211;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;lipid biosynthetic process#GO:0008610;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;protein lipidation#GO:0006497;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;glycerolipid biosynthetic process#GO:0045017;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;glycerophospholipid metabolic process#GO:0006650;phosphatidylinositol metabolic process#GO:0046488;organic substance biosynthetic process#GO:1901576;liposaccharide metabolic process#GO:1903509;cellular process#GO:0009987;GPI anchor metabolic process#GO:0006505;membrane lipid biosynthetic process#GO:0046467;lipoprotein biosynthetic process#GO:0042158;primary metabolic process#GO:0044238;GPI anchor biosynthetic process#GO:0006506;carbohydrate derivative biosynthetic process#GO:1901137;membrane lipid metabolic process#GO:0006643;glycerophospholipid biosynthetic process#GO:0046474;glycolipid biosynthetic process#GO:0009247;organophosphate metabolic process#GO:0019637;lipoprotein metabolic process#GO:0042157;cellular lipid metabolic process#GO:0044255 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 extracellular matrix glycoprotein#PC00100;extracellular matrix protein#PC00102 CIOIN|Ensembl=ENSCING00000004256.3|UniProtKB=F6YFT9 F6YFT9 PTHR11547:SF23 ARGININE OR CREATINE KINASE CREATINE KINASE B-TYPE transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301 organophosphate biosynthetic process#GO:0090407;nitrogen compound metabolic process#GO:0006807;cellular modified amino acid metabolic process#GO:0006575;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;organophosphate metabolic process#GO:0019637;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;metabolic process#GO:0008152;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 amino acid kinase#PC00045 CIOIN|Ensembl=ENSCING00000020796.1|UniProtKB=H2XT77 H2XT77 PTHR22906:SF48 PROPERDIN THROMBOSPONDIN TYPE 1 DOMAIN PROTEIN CIOIN|Ensembl=ENSCING00000003456.3|UniProtKB=F6UMX9 F6UMX9 PTHR23314:SF0 SPERM-ASSOCIATED ANTIGEN 6 ARMADILLO REPEAT-CONTAINING SPERM-ASSOCIATED ANTIGEN 6 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 microtubule-based movement#GO:0007018;cellular process#GO:0009987;microtubule-based process#GO:0007017;cilium movement#GO:0003341 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 microtubule or microtubule-binding cytoskeletal protein#PC00157 CIOIN|Ensembl=ENSCING00000019974.1|UniProtKB=H2XSC3 H2XSC3 PTHR46473:SF23 GH08155P GH08155P CIOIN|Ensembl=ENSCING00000019551.1|UniProtKB=H2XYN6 H2XYN6 PTHR43223:SF2 ALKYL/ARYL-SULFATASE METALLO-BETA-LACTAMASE DOMAIN-CONTAINING PROTEIN metabolite interconversion enzyme#PC00262;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000008975.3|UniProtKB=F6PLA8 F6PLA8 PTHR11909:SF155 CASEIN KINASE-RELATED GILGAMESH, ISOFORM L transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 signal transduction#GO:0007165;macromolecule modification#GO:0043412;transport#GO:0006810;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;endocytosis#GO:0006897;cellular metabolic process#GO:0044237;vesicle-mediated transport#GO:0016192;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cell communication#GO:0007154;cellular process#GO:0009987;primary metabolic process#GO:0044238;localization#GO:0051179;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;import into cell#GO:0098657 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 Wnt signaling pathway#P00057>Casein Kinase 1#P01460;Parkinson disease#P00049>Casein kinase I#P01242 CIOIN|Ensembl=ENSCING00000020747.1|UniProtKB=H2XVV3 H2XVV3 PTHR45635:SF14 ADP,ATP CARRIER PROTEIN 1-RELATED-RELATED ADP_ATP TRANSLOCASE transfer/carrier protein#PC00219 CIOIN|Ensembl=ENSCING00000012682.2|UniProtKB=F6U3J3 F6U3J3 PTHR15454:SF56 NISCHARIN RELATED PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 7-RELATED cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000004905.3|UniProtKB=F7AQQ6 F7AQQ6 PTHR11590:SF81 PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE K-LIKE ISOFORM X4 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000009842.3|UniProtKB=F6XGP0 F6XGP0 PTHR15071:SF34 MANNOSE-6-PHOSPHATE RECEPTOR FAMILY MEMBER MRH DOMAIN-CONTAINING PROTEIN cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;Golgi apparatus subcompartment#GO:0098791;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150 CIOIN|Ensembl=ENSCING00000012379.2|UniProtKB=F6Z8R5 F6Z8R5 LOC100177307 PTHR13256:SF16 N-ACETYLTRANSFERASE 9 ALPHA_BETA-TUBULIN-N-ACETYLTRANSFERASE 9 CIOIN|Ensembl=ENSCING00000003495.3|UniProtKB=F6TM52 F6TM52 PTHR32463:SF0 L-FUCOSE KINASE L-FUCOSE KINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301 cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;biosynthetic process#GO:0009058;nucleotide-sugar metabolic process#GO:0009225;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;heterocycle metabolic process#GO:0046483;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 kinase#PC00137 CIOIN|Ensembl=ENSCING00000018786.1|UniProtKB=H2Y3R5 H2Y3R5 LOC494373 PTHR15151:SF20 PROTEIN EIGER TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 12 molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;protein binding#GO:0005515;signaling receptor binding#GO:0005102 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 CIOIN|Ensembl=ENSCING00000005549.3|UniProtKB=F6XEA5 F6XEA5 LOC100183950 PTHR24246:SF27 OLFACTORY RECEPTOR AND ADENOSINE RECEPTOR ADENOSINE RECEPTOR, ISOFORM A G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711 CIOIN|Ensembl=ENSCING00000004181.3|UniProtKB=F7B5Q2 F7B5Q2 PTHR43876:SF7 UBIQUINONE BIOSYNTHESIS MONOOXYGENASE COQ6, MITOCHONDRIAL UBIQUINONE BIOSYNTHESIS MONOOXYGENASE COQ6, MITOCHONDRIAL oxygenase#PC00177;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000022099.1|UniProtKB=H2XQT6 H2XQT6 PTHR24221:SF402 ATP-BINDING CASSETTE SUB-FAMILY B IRON-SULFUR CLUSTERS TRANSPORTER ABCB7, MITOCHONDRIAL transmembrane transporter activity#GO:0022857;primary active transmembrane transporter activity#GO:0015399;ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215 localization#GO:0051179;inorganic ion homeostasis#GO:0098771;intracellular iron ion homeostasis#GO:0006879;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;intracellular monoatomic cation homeostasis#GO:0030003;transport#GO:0006810;homeostatic process#GO:0042592;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic ion homeostasis#GO:0006873;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;cellular process#GO:0009987;chemical homeostasis#GO:0048878;monoatomic ion homeostasis#GO:0050801 envelope#GO:0031975;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;organelle membrane#GO:0031090;organelle inner membrane#GO:0019866;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227 ATP-binding cassette (ABC) transporter#PC00003;transporter#PC00227 CIOIN|Ensembl=ENSCING00000022478.1|UniProtKB=H2XPT1 H2XPT1 LOC100177854 PTHR22298:SF29 ENDO-1,4-BETA-GLUCANASE ENDOGLUCANASE CIOIN|Ensembl=ENSCING00000024555.1|UniProtKB=H2XQX1 H2XQX1 PTHR11347:SF20 CYCLIC NUCLEOTIDE PHOSPHODIESTERASE PHOSPHODIESTERASE hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;cyclic-nucleotide phosphodiesterase activity#GO:0004112;phosphoric diester hydrolase activity#GO:0008081;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;cellular process#GO:0009987;cAMP-mediated signaling#GO:0019933;signaling#GO:0023052;cyclic-nucleotide-mediated signaling#GO:0019935 phosphodiesterase#PC00185 CIOIN|Ensembl=ENSCING00000010414.3|UniProtKB=F6XZR7 F6XZR7 PTHR22884:SF498 SET DOMAIN PROTEINS HISTONE-LYSINE N-METHYLTRANSFERASE ASHH3 N-methyltransferase activity#GO:0008170;histone modifying activity#GO:0140993;transferase activity#GO:0016740;catalytic activity#GO:0003824;histone methyltransferase activity#GO:0042054;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;protein-lysine N-methyltransferase activity#GO:0016279;catalytic activity, acting on a protein#GO:0140096;lysine N-methyltransferase activity#GO:0016278;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;protein methyltransferase activity#GO:0008276 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000004205.2|UniProtKB=F7ALJ6 F7ALJ6 PTHR13091:SF0 AMPLIFIED IN BREAST CANCER 2-RELATED NONSENSE-MEDIATED MRNA DECAY FACTOR SMG8 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;heterocycle catabolic process#GO:0046700;RNA metabolic process#GO:0016070;nucleobase-containing compound metabolic process#GO:0006139;cellular nitrogen compound catabolic process#GO:0044270;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;mRNA catabolic process#GO:0006402;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;organic substance catabolic process#GO:1901575;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;negative regulation of biosynthetic process#GO:0009890;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;nuclear-transcribed mRNA catabolic process#GO:0000956;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;nuclear-transcribed mRNA catabolic process, nonsense-mediated decay#GO:0000184;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;nucleobase-containing compound catabolic process#GO:0034655;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 CIOIN|Ensembl=ENSCING00000019958.1|UniProtKB=Q1RL31 Q1RL31 Ci-ZF(FYVE)-10 PTHR46603:SF1 ABSCISSION/NOCUT CHECKPOINT REGULATOR ABSCISSION_NOCUT CHECKPOINT REGULATOR CIOIN|Ensembl=ENSCING00000011844.2|UniProtKB=F6ZL37 F6ZL37 LOC100178461 PTHR12454:SF11 TRIMERIC INTRACELLULAR CATION CHANNEL GH25683P ion channel#PC00133;transporter#PC00227 CIOIN|Ensembl=ENSCING00000022225.1|UniProtKB=H2XYF4 H2XYF4 PTHR23503:SF8 SOLUTE CARRIER FAMILY 2 FACILITATED GLUCOSE TRANSPORTER PROTEIN 1 transmembrane transporter activity#GO:0022857;sugar transmembrane transporter activity#GO:0051119;transporter activity#GO:0005215;carbohydrate transmembrane transporter activity#GO:0015144 localization#GO:0051179;organic substance transport#GO:0071702;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810;cellular process#GO:0009987;carbohydrate transmembrane transport#GO:0034219;carbohydrate transport#GO:0008643 cellular anatomical entity#GO:0110165;membrane#GO:0016020 secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000021949.1|UniProtKB=F6YF07 F6YF07 PTHR10127:SF780 DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING METALLOENDOPEPTIDASE hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000021983.1|UniProtKB=H2XM76 H2XM76 PTHR23138:SF87 RAN BINDING PROTEIN E3 SUMO-PROTEIN LIGASE RANBP2 nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 envelope#GO:0031975;cytoplasm#GO:0005737;nuclear pore#GO:0005643;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear envelope#GO:0005635;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000013719.2|UniProtKB=F6Z163 F6Z163 PTHR22906:SF43 PROPERDIN PROPERDIN CIOIN|Ensembl=ENSCING00000023742.1|UniProtKB=H2XLV9 H2XLV9 PTHR24074:SF56 CO-CHAPERONE PROTEIN DJLA LD30543P chaperone#PC00072 CIOIN|Ensembl=ENSCING00000012786.2|UniProtKB=F6XCS0 F6XCS0 PTHR23147:SF270 SERINE/ARGININE RICH SPLICING FACTOR RNA-BINDING PROTEIN RNP-1 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;nuclear speck#GO:0016607;organelle#GO:0043226;nuclear body#GO:0016604;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA splicing factor#PC00148;RNA processing factor#PC00147;RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000022596.1|UniProtKB=H2Y1Q2 H2Y1Q2 PTHR19444:SF13 UNC-93 RELATED PROTEIN UNC-93 HOMOLOG A membrane-bound signaling molecule#PC00152 CIOIN|Ensembl=ENSCING00000020506.1|UniProtKB=H2Y2D7 H2Y2D7 LOC100175410 PTHR31993:SF4 UBA-LIKE DOMAIN-CONTAINING PROTEIN 2 UBA-LIKE DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000005279.1|UniProtKB=F6UIW1 F6UIW1 PTHR10640:SF7 METHYLTHIORIBULOSE-1-PHOSPHATE DEHYDRATASE METHYLTHIORIBULOSE-1-PHOSPHATE DEHYDRATASE lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835;hydro-lyase activity#GO:0016836;catalytic activity#GO:0003824 organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;proteinogenic amino acid metabolic process#GO:0170039;sulfur compound metabolic process#GO:0006790;proteinogenic amino acid biosynthetic process#GO:0170038;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;aspartate family amino acid biosynthetic process#GO:0009067;alpha-amino acid biosynthetic process#GO:1901607;nitrogen compound metabolic process#GO:0006807;amino acid biosynthetic process#GO:0008652;alpha-amino acid metabolic process#GO:1901605;aspartate family amino acid metabolic process#GO:0009066;small molecule biosynthetic process#GO:0044283;L-amino acid biosynthetic process#GO:0170034;carboxylic acid metabolic process#GO:0019752;L-amino acid metabolic process#GO:0170033;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 dehydratase#PC00091;lyase#PC00144 CIOIN|Ensembl=ENSCING00000012486.2|UniProtKB=F6U5N1 F6U5N1 PTHR11360:SF284 MONOCARBOXYLATE TRANSPORTER EG:103B4.3 PROTEIN-RELATED transporter#PC00227 CIOIN|Ensembl=ENSCING00000006564.3|UniProtKB=F6RI21 F6RI21 PTHR11348:SF17 CONNECTIVE TISSUE GROWTH FACTOR-RELATED CCN carbohydrate derivative binding#GO:0097367;integrin binding#GO:0005178;binding#GO:0005488;heparin binding#GO:0008201;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;glycosaminoglycan binding#GO:0005539;signaling receptor binding#GO:0005102 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;positive regulation of cell differentiation#GO:0045597;cell communication#GO:0007154;cell adhesion#GO:0007155;cellular process#GO:0009987;regulation of cell differentiation#GO:0045595;positive regulation of developmental process#GO:0051094;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;biological regulation#GO:0065007;signaling#GO:0023052;positive regulation of biological process#GO:0048518 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;extracellular space#GO:0005615;extracellular region#GO:0005576 growth factor#PC00112 CIOIN|Ensembl=ENSCING00000007582.3|UniProtKB=H2XL84 H2XL84 LOC100179273 PTHR13237:SF8 SOMETHING ABOUT SILENCING PROTEIN 10-RELATED SOMETHING ABOUT SILENCING PROTEIN 10 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;maturation of SSU-rRNA#GO:0030490;ribosomal small subunit biogenesis#GO:0042274;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;small-subunit processome#GO:0032040;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;nuclear lumen#GO:0031981 RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000012090.2|UniProtKB=F6XV61 F6XV61 PTHR45704:SF16 RAS-LIKE FAMILY MEMBER 11 RAS-RELATED AND ESTROGEN-REGULATED GROWTH INHIBITOR CIOIN|Ensembl=ENSCING00000012985.2|UniProtKB=F6VV11 F6VV11 LOC100183521 PTHR36871:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 190 COILED-COIL DOMAIN-CONTAINING PROTEIN 190 CIOIN|Ensembl=ENSCING00000009822.3|UniProtKB=F6Y506 F6Y506 PTHR12080:SF117 SIGNALING LYMPHOCYTIC ACTIVATION MOLECULE CHITINASE immunoglobulin receptor superfamily#PC00124 CIOIN|Ensembl=ENSCING00000007535.3|UniProtKB=F7AVW9 F7AVW9 PTHR24115:SF1011 KINESIN-RELATED KINESIN-LIKE PROTEIN KLP98A pyrophosphatase activity#GO:0016462;cytoskeletal protein binding#GO:0008092;microtubule motor activity#GO:0003777;tubulin binding#GO:0015631;ATP-dependent activity#GO:0140657;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;cytoskeletal motor activity#GO:0003774;microtubule binding#GO:0008017;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;ribonucleoside triphosphate phosphatase activity#GO:0017111;ATP hydrolysis activity#GO:0016887 vesicle transport along microtubule#GO:0047496;cellular localization#GO:0051641;organelle localization#GO:0051640;vesicle localization#GO:0051648;transport#GO:0006810;microtubule-based movement#GO:0007018;cellular process#GO:0009987;transport along microtubule#GO:0010970;localization#GO:0051179;microtubule-based transport#GO:0099111;establishment of localization#GO:0051234;microtubule-based process#GO:0007017;establishment of vesicle localization#GO:0051650;cytoskeleton-dependent intracellular transport#GO:0030705;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;organelle transport along microtubule#GO:0072384;establishment of organelle localization#GO:0051656;vesicle cytoskeletal trafficking#GO:0099518 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;microtubule associated complex#GO:0005875;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 CIOIN|Ensembl=ENSCING00000005329.3|UniProtKB=F7BPA9 F7BPA9 LOC100178249 PTHR31340:SF5 MITOCHONDRIAL GENOME MAINTENANCE EXONUCLEASE 1 MITOCHONDRIAL GENOME MAINTENANCE EXONUCLEASE 1 hydrolase activity, acting on ester bonds#GO:0016788;DNA exonuclease activity, producing 5'-phosphomonoesters#GO:0016895;nuclease activity#GO:0004518;DNA exonuclease activity#GO:0004529;catalytic activity#GO:0003824;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters#GO:0016796;hydrolase activity#GO:0016787;catalytic activity, acting on a nucleic acid#GO:0140640;DNA nuclease activity#GO:0004536;catalytic activity, acting on DNA#GO:0140097;exonuclease activity#GO:0004527 cellular aromatic compound metabolic process#GO:0006725;mitochondrial genome maintenance#GO:0000002;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;mitochondrial DNA metabolic process#GO:0032042;organelle organization#GO:0006996;nitrogen compound metabolic process#GO:0006807;DNA-templated DNA replication#GO:0006261;mitochondrion organization#GO:0007005;DNA replication#GO:0006260;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000002266.3|UniProtKB=F6RQC5 F6RQC5 LOC100180197 PTHR31793:SF27 4-HYDROXYBENZOYL-COA THIOESTERASE FAMILY MEMBER NOVEL THIOESTERASE SUPERFAMILY DOMAIN AND SAPOSIN A-TYPE DOMAIN CONTAINING PROTEIN (0610012H03RIK) hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;fatty acyl-CoA hydrolase activity#GO:0047617;catalytic activity#GO:0003824;thiolester hydrolase activity#GO:0016790 esterase#PC00097;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000002163.3|UniProtKB=Q8T886 Q8T886 Ci-pf-rib PTHR14517:SF6 RIB43A-RELATED RE41410P cytoskeletal protein#PC00085 CIOIN|Ensembl=ENSCING00000004649.3|UniProtKB=F6RMW3 F6RMW3 LOC100179685 PTHR43920:SF5 CHLORIDE INTRACELLULAR CHANNEL, ISOFORM A CHLORIDE INTRACELLULAR CHANNEL CLIC inorganic molecular entity transmembrane transporter activity#GO:0015318;chloride channel activity#GO:0005254;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;chloride transmembrane transporter activity#GO:0015108;monoatomic anion transmembrane transporter activity#GO:0008509;inorganic anion transmembrane transporter activity#GO:0015103;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267;monoatomic ion channel activity#GO:0005216 localization#GO:0051179;chloride transport#GO:0006821;monoatomic ion transport#GO:0006811;establishment of localization#GO:0051234;inorganic anion transport#GO:0015698;monoatomic anion transport#GO:0006820;transport#GO:0006810 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;membrane#GO:0016020;intracellular anatomical structure#GO:0005622 ion channel#PC00133;transporter#PC00227 CIOIN|Ensembl=ENSCING00000007153.3|UniProtKB=A0A1W2WEN5 A0A1W2WEN5 LOC100176797 PTHR11937:SF387 ACTIN ACTIN-LIKE PROTEIN 53D intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 actin and actin related protein#PC00039;cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 Wnt signaling pathway#P00057>NFAT Target Genes#G01559;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>F-actin#P00858;Alzheimer disease-presenilin pathway#P00004>actin#P00114;Integrin signalling pathway#P00034>Actin#P00944;Huntington disease#P00029>Actin#P00807;Nicotinic acetylcholine receptor signaling pathway#P00044>Actin#P01090;Cadherin signaling pathway#P00012>F-actin#P00470;Cytoskeletal regulation by Rho GTPase#P00016>Actin#P00512 CIOIN|Ensembl=ENSCING00000008943.3|UniProtKB=F6Q6M5 F6Q6M5 PTHR15031:SF4 CARTILAGE INTERMEDIATE LAYER PROTEIN CLIP CARTILAGE INTERMEDIATE LAYER PROTEIN 1 CIOIN|Ensembl=ENSCING00000016914.2|UniProtKB=F6PN33 F6PN33 PTHR24418:SF294 TYROSINE-PROTEIN KINASE TYROSINE-PROTEIN KINASE BTK29A protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 non-receptor tyrosine protein kinase#PC00168 CIOIN|Ensembl=ENSCING00000023675.1|UniProtKB=A0A1W5BF98 A0A1W5BF98 LOC100186402 PTHR21093:SF2 DIVERGENT PROTEIN KINASE DOMAIN 1C-RELATED DIVERGENT PROTEIN KINASE DOMAIN 1C CIOIN|Ensembl=ENSCING00000002990.3|UniProtKB=F6QXX8 F6QXX8 LOC100176246 PTHR10666:SF173 UBIQUITIN NEDD8 enzyme binding#GO:0019899;protein binding#GO:0005515;ubiquitin protein ligase binding#GO:0031625;binding#GO:0005488;ubiquitin-like protein ligase binding#GO:0044389 protein neddylation#GO:0045116;regulation of proteolysis#GO:0030162;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;regulation of protein metabolic process#GO:0051246;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;regulation of nitrogen compound metabolic process#GO:0051171;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;modification-dependent macromolecule catabolic process#GO:0043632;regulation of primary metabolic process#GO:0080090;regulation of macromolecule metabolic process#GO:0060255;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;biological regulation#GO:0065007;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;proteolysis involved in protein catabolic process#GO:0051603;regulation of metabolic process#GO:0019222;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000003037.3|UniProtKB=F6Q9M1 F6Q9M1 PTHR24256:SF570 TRYPTASE-RELATED CLIP-DOMAIN SERINE PROTEASE hydrolase activity#GO:0016787;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 serine protease#PC00203;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000003542.3|UniProtKB=Q1RL32 Q1RL32 Ci-ZF(FYVE)-9 PTHR46280:SF3 PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY F MEMBER 2-RELATED PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY F MEMBER 1 HOMOLOG CIOIN|Ensembl=ENSCING00000023446.1|UniProtKB=H2XK77 H2XK77 PTHR11929:SF145 ALPHA- 1,3 -FUCOSYLTRANSFERASE ALPHA-(1,3)-FUCOSYLTRANSFERASE FUT-1 transferase activity#GO:0016740;fucosyltransferase activity#GO:0008417;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 glycosylation#GO:0070085;metabolic process#GO:0008152 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000009391.3|UniProtKB=F6UAH7 F6UAH7 PTHR13466:SF0 TEX2 PROTEIN-RELATED SMP-LTD DOMAIN-CONTAINING PROTEIN lipid binding#GO:0008289;binding#GO:0005488 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000020617.1|UniProtKB=H2XQK5 H2XQK5 PTHR10983:SF2 1-ACYLGLYCEROL-3-PHOSPHATE ACYLTRANSFERASE-RELATED ACYL-COA:LYSOPHOSPHATIDYLGLYCEROL ACYLTRANSFERASE 1 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;glycerolipid metabolic process#GO:0046486;cellular metabolic process#GO:0044237;phosphatidylinositol metabolic process#GO:0046488;organophosphate metabolic process#GO:0019637;glycerophospholipid metabolic process#GO:0006650;cellular process#GO:0009987;phospholipid metabolic process#GO:0006644;cellular lipid metabolic process#GO:0044255;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 acyltransferase#PC00042 CIOIN|Ensembl=ENSCING00000024111.1|UniProtKB=H2XUV5 H2XUV5 PTHR11258:SF11 2-5 OLIGOADENYLATE SYNTHETASE C2H2-TYPE DOMAIN-CONTAINING PROTEIN adenylyltransferase activity#GO:0070566;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;transferase activity#GO:0016740;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;nucleotidyltransferase activity#GO:0016779;transferase activity, transferring phosphorus-containing groups#GO:0016772;double-stranded RNA binding#GO:0003725 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule metabolic process#GO:0060255;regulation of molecular function#GO:0065009;regulation of nitrogen compound metabolic process#GO:0051171;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of hydrolase activity#GO:0051336;regulation of catalytic activity#GO:0050790;regulation of RNA metabolic process#GO:0051252;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 nucleotidyltransferase#PC00174 CIOIN|Ensembl=ENSCING00000003056.3|UniProtKB=F6PPP3 F6PPP3 PTHR23389:SF3 CHROMOSOME TRANSMISSION FIDELITY FACTOR 18 CHROMOSOME TRANSMISSION FIDELITY PROTEIN 18 HOMOLOG nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA metabolism protein#PC00009 CIOIN|Ensembl=ENSCING00000003814.3|UniProtKB=F6YR14 F6YR14 PTHR23503:SF132 SOLUTE CARRIER FAMILY 2 SOLUTE CARRIER FAMILY 2, FACILITATED GLUCOSE TRANSPORTER MEMBER 5-LIKE transmembrane transporter activity#GO:0022857;sugar transmembrane transporter activity#GO:0051119;transporter activity#GO:0005215;carbohydrate transmembrane transporter activity#GO:0015144 localization#GO:0051179;organic substance transport#GO:0071702;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;organic anion transport#GO:0015711;transport#GO:0006810;vitamin transport#GO:0051180;glucose transmembrane transport#GO:1904659;cellular process#GO:0009987;carbohydrate transmembrane transport#GO:0034219;carbohydrate transport#GO:0008643 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000020631.1|UniProtKB=H2XPK9 H2XPK9 PTHR23003:SF51 RNA RECOGNITION MOTIF RRM DOMAIN CONTAINING PROTEIN SERINE-ARGININE PROTEIN 55 nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA splicing factor#PC00148;RNA processing factor#PC00147;RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000008945.3|UniProtKB=F6U637 F6U637 PTHR10338:SF108 INTER-ALPHA-TRYPSIN INHIBITOR HEAVY CHAIN FAMILY MEMBER INTER-ALPHA-TRYPSIN INHIBITOR HEAVY CHAIN H4-LIKE PROTEIN protease inhibitor#PC00191;protein-binding activity modulator#PC00095 CIOIN|Ensembl=ENSCING00000015563.2|UniProtKB=F7A491 F7A491 LOC100182633 PTHR46222:SF3 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP7/14 PEPTIDYLPROLYL ISOMERASE chaperone#PC00072 CIOIN|Ensembl=ENSCING00000019310.1|UniProtKB=H2XXV9 H2XXV9 PTHR47456:SF6 PHD-TYPE DOMAIN-CONTAINING PROTEIN SI:DKEY-31C13.1 CIOIN|Ensembl=ENSCING00000000169.3|UniProtKB=F6S6I4 F6S6I4 LOC100182900 PTHR11157:SF17 FATTY ACID ACYL TRANSFERASE-RELATED ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN 6 acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824 organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;monocarboxylic acid biosynthetic process#GO:0072330;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;organic acid metabolic process#GO:0006082;membrane lipid biosynthetic process#GO:0046467;sphingolipid metabolic process#GO:0006665;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;fatty acid metabolic process#GO:0006631;membrane lipid metabolic process#GO:0006643;nitrogen compound metabolic process#GO:0006807;small molecule biosynthetic process#GO:0044283;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;sphingolipid biosynthetic process#GO:0030148;fatty acid biosynthetic process#GO:0006633;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 acyltransferase#PC00042 CIOIN|Ensembl=ENSCING00000005185.3|UniProtKB=F7B7G6 F7B7G6 LOC100184614 PTHR24031:SF96 RNA HELICASE ATP-DEPENDENT RNA HELICASE DDX56-RELATED intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA helicase#PC00032 CIOIN|Ensembl=ENSCING00000004284.3|UniProtKB=F6UG35 F6UG35 PTHR24413:SF213 SPECKLE-TYPE POZ PROTEIN FI01029P-RELATED enzyme binding#GO:0019899;protein binding#GO:0005515;ubiquitin protein ligase binding#GO:0031625;binding#GO:0005488;ubiquitin-like protein ligase binding#GO:0044389 regulation of proteolysis#GO:0030162;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;regulation of protein metabolic process#GO:0051246;macromolecule metabolic process#GO:0043170;regulation of nitrogen compound metabolic process#GO:0051171;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of biological process#GO:0050789;modification-dependent macromolecule catabolic process#GO:0043632;regulation of primary metabolic process#GO:0080090;regulation of macromolecule metabolic process#GO:0060255;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;biological regulation#GO:0065007;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;regulation of metabolic process#GO:0019222;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000024854.1|UniProtKB=F6XX55 F6XX55 PTHR24412:SF497 KELCH PROTEIN KELCH-LIKE PROTEIN 18 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000003478.3|UniProtKB=F6U9S8 F6U9S8 PTHR12654:SF0 BILE ACID BETA-GLUCOSIDASE-RELATED NON-LYSOSOMAL GLUCOSYLCERAMIDASE glucosidase#PC00108;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000001750.3|UniProtKB=F7AME7 F7AME7 PTHR23235:SF142 KRUEPPEL-LIKE TRANSCRIPTION FACTOR ZINC FINGER PROTEIN 384 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 CIOIN|Ensembl=ENSCING00000017566.2|UniProtKB=A0A1W2WA63 A0A1W2WA63 LOC100185572 PTHR22761:SF10 CHARGED MULTIVESICULAR BODY PROTEIN GH13992P endosomal transport#GO:0016197;cellular localization#GO:0051641;membrane organization#GO:0061024;vacuolar transport#GO:0007034;transport#GO:0006810;late endosome to vacuole transport via multivesicular body sorting pathway#GO:0032511;vesicle-mediated transport#GO:0016192;late endosome to vacuole transport#GO:0045324;cellular component organization#GO:0016043;cellular process#GO:0009987;multivesicular body sorting pathway#GO:0071985;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;vesicle budding from membrane#GO:0006900;establishment of localization#GO:0051234;organelle organization#GO:0006996;endosome transport via multivesicular body sorting pathway#GO:0032509;establishment of localization in cell#GO:0051649;vesicle organization#GO:0016050;intracellular transport#GO:0046907 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;endosome membrane#GO:0010008;membrane#GO:0016020;side of membrane#GO:0098552;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle membrane#GO:0030659;late endosome#GO:0005770;cytoplasmic side of plasma membrane#GO:0009898;plasma membrane#GO:0005886 membrane traffic protein#PC00150 CIOIN|Ensembl=ENSCING00000020982.1|UniProtKB=H2XSM3 H2XSM3 PTHR12394:SF12 ZYGIN LD08195P cytoplasm#GO:0005737;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;neuron projection#GO:0043005;intracellular anatomical structure#GO:0005622;axon#GO:0030424 CIOIN|Ensembl=ENSCING00000017942.1|UniProtKB=H2XQ28 H2XQ28 LOC100184420 PTHR11733:SF114 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED NEPRILYSIN hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;protein processing#GO:0016485;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000024017.1|UniProtKB=H2XU55 H2XU55 PTHR13803:SF36 SEC24-RELATED PROTEIN TYPE A VON WILLEBRAND FACTOR DOMAIN-CONTAINING PROTEIN cation binding#GO:0043169;small molecule binding#GO:0036094;zinc ion binding#GO:0008270;binding#GO:0005488;transition metal ion binding#GO:0046914;metal ion binding#GO:0046872;protein binding#GO:0005515;ion binding#GO:0043167;SNARE binding#GO:0000149 endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;membrane organization#GO:0061024;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;COPII-coated vesicle budding#GO:0090114;establishment of localization in cell#GO:0051649;vesicle organization#GO:0016050;intracellular transport#GO:0046907 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;ER to Golgi transport vesicle membrane#GO:0012507;endoplasmic reticulum exit site#GO:0070971;COPII-coated ER to Golgi transport vesicle#GO:0030134;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;coated vesicle#GO:0030135;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;vesicle coat#GO:0030120;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;transport vesicle membrane#GO:0030658;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;membrane coat#GO:0030117;coated vesicle membrane#GO:0030662;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;transport vesicle#GO:0030133;coated membrane#GO:0048475;cytoplasmic vesicle membrane#GO:0030659;endoplasmic reticulum#GO:0005783 vesicle coat protein#PC00235 CIOIN|Ensembl=ENSCING00000001858.3|UniProtKB=F6T6Y7 F6T6Y7 PTHR46754:SF1 MKI67 FHA DOMAIN-INTERACTING NUCLEOLAR PHOSPHOPROTEIN MKI67 FHA DOMAIN-INTERACTING NUCLEOLAR PHOSPHOPROTEIN nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;RNA processing#GO:0006396;gene expression#GO:0010467;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;ribosomal large subunit biogenesis#GO:0042273;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;maturation of LSU-rRNA#GO:0000470;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000020586.1|UniProtKB=H2XMZ4 H2XMZ4 LOC100182888 PTHR33887:SF6 PB1 DOMAIN-CONTAINING PROTEIN CIDE-N DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000019745.1|UniProtKB=H2Y2A8 H2Y2A8 LOC100176168 PTHR46493:SF1 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP3 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP3 chaperone#PC00072 CIOIN|Ensembl=ENSCING00000013897.2|UniProtKB=F6Q162 F6Q162 PTHR24256:SF470 TRYPTASE-RELATED INACTIVE CLIP DOMAIN-CONTAINING SERINE PROTEASE A30 serine protease#PC00203;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000023378.1|UniProtKB=H2XQ55 H2XQ55 PTHR35083:SF1 RGD1565685 PROTEIN RGD1565685 PROTEIN CIOIN|Ensembl=ENSCING00000005598.3|UniProtKB=F6TFJ1 F6TFJ1 PTHR12765:SF5 RED PROTEIN IK FACTOR CYTOKINE IK PROTEIN RED cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytokine#PC00083 CIOIN|Ensembl=ENSCING00000001828.2|UniProtKB=F6WIJ0 F6WIJ0 LOC100184340 PTHR21641:SF0 TRANSLATION INITIATION FACTOR-RELATED RNA-BINDING PROTEIN EIF1AD-RELATED membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 translation initiation factor#PC00224;translation factor#PC00223;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000023834.1|UniProtKB=H2XS56 H2XS56 PTHR24132:SF24 ANKYRIN REPEAT AND SOCS BOX PROTEIN 6 ANKYRIN REPEAT AND SOCS BOX PROTEIN 6 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000002735.3|UniProtKB=F6TPL8 F6TPL8 LOC445593 PTHR11475:SF121 OXIDASE/PEROXIDASE THYROID PEROXIDASE-LIKE oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;antioxidant activity#GO:0016209;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 peroxidase#PC00180;oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000003214.3|UniProtKB=F7BBJ9 F7BBJ9 PTHR11624:SF96 DEHYDROGENASE RELATED PYRUVATE DEHYDROGENASE E1 COMPONENT SUBUNIT BETA, MITOCHONDRIAL oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;amide metabolic process#GO:0043603;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;acyl-CoA metabolic process#GO:0006637;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;monocarboxylic acid metabolic process#GO:0032787;purine ribonucleotide metabolic process#GO:0009150;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;carboxylic acid metabolic process#GO:0019752;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 dehydrogenase#PC00092;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000008037.3|UniProtKB=F6S5D5 F6S5D5 LOC100181904 PTHR43731:SF14 RHOMBOID PROTEASE PRESENILIN-ASSOCIATED RHOMBOID-LIKE PROTEIN, MITOCHONDRIAL hydrolase activity#GO:0016787;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171 serine protease#PC00203;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000023874.1|UniProtKB=H2XRU3 H2XRU3 LOC100183183 PTHR13073:SF0 BLOC-1 COMPLEX SUBUNIT 1 BIOGENESIS OF LYSOSOME-RELATED ORGANELLES COMPLEX 1 SUBUNIT 1 localization#GO:0051179;endosomal transport#GO:0016197;cellular localization#GO:0051641;establishment of localization#GO:0051234;transport#GO:0006810;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;cellular process#GO:0009987 protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535 membrane traffic protein#PC00150 CIOIN|Ensembl=ENSCING00000013417.2|UniProtKB=F6V3M5 F6V3M5 LOC100180420 PTHR22957:SF676 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER 2B nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 regulation of molecular function#GO:0065009;regulation of GTPase activity#GO:0043087;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;activation of GTPase activity#GO:0090630;biological regulation#GO:0065007;positive regulation of molecular function#GO:0044093;regulation of hydrolase activity#GO:0051336;regulation of catalytic activity#GO:0050790;positive regulation of hydrolase activity#GO:0051345 GTPase-activating protein#PC00257 CIOIN|Ensembl=ENSCING00000005983.3|UniProtKB=F6V5U6 F6V5U6 PTHR11550:SF0 CTP SYNTHASE CTP SYNTHASE-RELATED identical protein binding#GO:0042802;ligase activity#GO:0016874;protein binding#GO:0005515;binding#GO:0005488;catalytic activity#GO:0003824 ribonucleoside triphosphate metabolic process#GO:0009199;cellular aromatic compound metabolic process#GO:0006725;nucleoside triphosphate metabolic process#GO:0009141;pyrimidine nucleotide metabolic process#GO:0006220;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;pyrimidine-containing compound metabolic process#GO:0072527;biosynthetic process#GO:0009058;nucleobase metabolic process#GO:0009112;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;nucleotide biosynthetic process#GO:0009165;pyrimidine nucleobase metabolic process#GO:0006206;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;ribonucleoside triphosphate biosynthetic process#GO:0009201;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;nucleoside triphosphate biosynthetic process#GO:0009142;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 ligase#PC00142;metabolite interconversion enzyme#PC00262 De novo pyrimidine ribonucleotides biosythesis#P02740>CTP synthase#P02931 CIOIN|Ensembl=ENSCING00000008497.3|UniProtKB=F7B2M5 F7B2M5 PTHR42765:SF1 SOLEUCYL-TRNA SYNTHETASE ISOLEUCINE--TRNA LIGASE, MITOCHONDRIAL catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;ligase activity#GO:0016874;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;peptide biosynthetic process#GO:0043043;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 aminoacyl-tRNA synthetase#PC00047;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000002113.3|UniProtKB=F6WRZ9 F6WRZ9 LOC100186693 PTHR23055:SF178 CALCIUM BINDING PROTEINS NEUROCALCIN HOMOLOG cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488 calmodulin-related#PC00061 CIOIN|Ensembl=ENSCING00000006357.3|UniProtKB=F6PQZ3 F6PQZ3 LOC100185464 PTHR15382:SF8 CTG4A-RELATED CANOPY B CIOIN|Ensembl=ENSCING00000004308.3|UniProtKB=F6TSK2 F6TSK2 LOC100187142 PTHR22600:SF21 BETA-HEXOSAMINIDASE BETA-HEXOSAMINIDASE A hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 glycosaminoglycan metabolic process#GO:0030203;carbohydrate derivative metabolic process#GO:1901135;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;aminoglycan metabolic process#GO:0006022;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;membrane#GO:0016020 glycosidase#PC00110;metabolite interconversion enzyme#PC00262;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000022094.1|UniProtKB=H2XTC6 H2XTC6 LOC100186985 PTHR11588:SF6 TUBULIN TUBULIN_FTSZ GTPASE DOMAIN-CONTAINING PROTEIN carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;structural molecule activity#GO:0005198;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167;structural constituent of cytoskeleton#GO:0005200 cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;microtubule-based process#GO:0007017;organelle organization#GO:0006996;microtubule cytoskeleton organization#GO:0000226;cytoskeleton organization#GO:0007010;cell cycle#GO:0007049;cellular component organization#GO:0016043;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622 tubulin#PC00228;microtubule or microtubule-binding cytoskeletal protein#PC00157 CIOIN|Ensembl=ENSCING00000021322.1|UniProtKB=H2XTJ6 H2XTJ6 PTHR22846:SF2 WD40 REPEAT PROTEIN F-BOX-LIKE_WD REPEAT-CONTAINING PROTEIN EBI molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714;protein-macromolecule adaptor activity#GO:0030674 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;histone deacetylase complex#GO:0000118;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 Wnt signaling pathway#P00057>Ebi#P01453 CIOIN|Ensembl=ENSCING00000016095.2|UniProtKB=F6VJ33 F6VJ33 LOC100186706 PTHR24264:SF65 TRYPSIN-RELATED SRCR DOMAIN-CONTAINING PROTEIN hydrolase activity#GO:0016787;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 serine protease#PC00203;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000024203.1|UniProtKB=H2XT20 H2XT20 PTHR46543:SF1 ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 7 ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 7 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;heterocycle catabolic process#GO:0046700;RNA metabolic process#GO:0016070;nucleobase-containing compound metabolic process#GO:0006139;cellular nitrogen compound catabolic process#GO:0044270;modification-dependent macromolecule catabolic process#GO:0043632;regulation of biological process#GO:0050789;ncRNA metabolic process#GO:0034660;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;mRNA catabolic process#GO:0006402;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance catabolic process#GO:1901575;negative regulation of cellular process#GO:0048523;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;snRNA metabolic process#GO:0016073;negative regulation of biosynthetic process#GO:0009890;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;nuclear-transcribed mRNA catabolic process#GO:0000956;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;rRNA metabolic process#GO:0016072;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;nucleobase-containing compound catabolic process#GO:0034655;polyadenylation-dependent ncRNA catabolic process#GO:0043634;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000006132.3|UniProtKB=F6V304 F6V304 LOC100180811 PTHR12281:SF32 RP42 RELATED DCN1-LIKE PROTEIN cullin family protein binding#GO:0097602;enzyme binding#GO:0019899;ubiquitin-like protein conjugating enzyme binding#GO:0044390;protein binding#GO:0005515;ubiquitin-like protein binding#GO:0032182;binding#GO:0005488 protein neddylation#GO:0045116;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;transferase complex#GO:1990234 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000025102.1|UniProtKB=H2XJJ8 H2XJJ8 PTHR48024:SF56 GEO13361P1-RELATED HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN A0 CIOIN|Ensembl=ENSCING00000003975.3|UniProtKB=F6ZBI9 F6ZBI9 PTHR11742:SF6 MANNOSYL-OLIGOSACCHARIDE ALPHA-1,2-MANNOSIDASE-RELATED MANNOSYL-OLIGOSACCHARIDE ALPHA-1,2-MANNOSIDASE IA-RELATED hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 carbohydrate derivative metabolic process#GO:1901135;macromolecule modification#GO:0043412;protein catabolic process#GO:0030163;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;glycoprotein metabolic process#GO:0009100;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;macromolecule catabolic process#GO:0009057;response to endoplasmic reticulum stress#GO:0034976;response to oxygen-containing compound#GO:1901700;macromolecule metabolic process#GO:0043170;carbohydrate derivative catabolic process#GO:1901136;organonitrogen compound metabolic process#GO:1901564;ERAD pathway#GO:0036503;response to organonitrogen compound#GO:0010243;cellular process#GO:0009987;primary metabolic process#GO:0044238;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;cellular response to stress#GO:0033554 bounding membrane of organelle#GO:0098588;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;Golgi membrane#GO:0000139;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000021006.1|UniProtKB=H2Y1C3 H2Y1C3 PTHR13356:SF0 OB FOLD NUCLEIC ACID BINDING PROTEIN-RELATED SOSS COMPLEX SUBUNIT B HOMOLOG nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;double-strand break repair via homologous recombination#GO:0000724;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;DNA damage response#GO:0006974;response to stress#GO:0006950;organic cyclic compound metabolic process#GO:1901360;response to radiation#GO:0009314;nitrogen compound metabolic process#GO:0006807;recombinational repair#GO:0000725;response to abiotic stimulus#GO:0009628;cellular response to stress#GO:0033554;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;organic substance metabolic process#GO:0071704 damaged DNA-binding protein#PC00086 CIOIN|Ensembl=ENSCING00000024330.1|UniProtKB=H2XKP7 H2XKP7 PTHR45755:SF4 FAMILY NOT NAMED ZINC TRANSPORTER 7 inorganic molecular entity transmembrane transporter activity#GO:0015318;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873 localization#GO:0051179;monoatomic cation transport#GO:0006812;metal ion transport#GO:0030001;establishment of localization#GO:0051234;monoatomic ion transport#GO:0006811;transport#GO:0006810 CIOIN|Ensembl=ENSCING00000002987.3|UniProtKB=F6QY94 F6QY94 LOC100182913 PTHR23309:SF49 3-HYDROXYACYL-COA DEHYROGENASE PEROXISOMAL BIFUNCTIONAL ENZYME oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;lipid oxidation#GO:0034440;cellular metabolic process#GO:0044237;lipid catabolic process#GO:0016042;lipid modification#GO:0030258;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;fatty acid catabolic process#GO:0009062;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;fatty acid metabolic process#GO:0006631;small molecule catabolic process#GO:0044282;fatty acid beta-oxidation#GO:0006635;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;cellular lipid metabolic process#GO:0044255;cellular lipid catabolic process#GO:0044242;carboxylic acid metabolic process#GO:0019752;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;monocarboxylic acid catabolic process#GO:0072329 dehydrogenase#PC00092;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000006853.3|UniProtKB=F6ZXE7 F6ZXE7 PTHR24412:SF272 KELCH PROTEIN KELCH-LIKE PROTEIN DIABLO scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000005536.3|UniProtKB=A0A1W5BHV7 A0A1W5BHV7 LOC100176371 PTHR45665:SF9 AQUAPORIN-8 AQUAPORIN-8 inorganic molecular entity transmembrane transporter activity#GO:0015318;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;channel activity#GO:0015267;water transmembrane transporter activity#GO:0005372 localization#GO:0051179;water transport#GO:0006833;establishment of localization#GO:0051234;fluid transport#GO:0042044;transport#GO:0006810 cellular anatomical entity#GO:0110165;membrane#GO:0016020 CIOIN|Ensembl=ENSCING00000001921.3|UniProtKB=F6ZJ69 F6ZJ69 LOC100178597 PTHR17068:SF11 MYELOID-ASSOCIATED DIFFERENTIATION MARKER MYADM FAMILY MEMBER MYELOID-ASSOCIATED DIFFERENTIATION MARKER-LIKE PROTEIN 2 CIOIN|Ensembl=ENSCING00000007815.3|UniProtKB=F6WHA2 F6WHA2 PTHR19282:SF252 TETRASPANIN TETRASPANIN cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000014912.2|UniProtKB=F6Y7W5 F6Y7W5 LOC100184985 PTHR21706:SF15 TRANSMEMBRANE PROTEIN 65 TRANSMEMBRANE PROTEIN 65 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000009949.3|UniProtKB=A0A1W5BKF1 A0A1W5BKF1 LOC101242356 PTHR35440:SF1 TESTIS-EXPRESSED PROTEIN 36 TESTIS-EXPRESSED PROTEIN 36 CIOIN|Ensembl=ENSCING00000015335.2|UniProtKB=F7AP79 F7AP79 PTHR11188:SF176 ARRESTIN DOMAIN CONTAINING PROTEIN ARRESTIN DOMAIN-CONTAINING PROTEIN 1 localization#GO:0051179;organic substance transport#GO:0071702;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;transport#GO:0006810;protein transport#GO:0015031;nitrogen compound transport#GO:0071705;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000009659.3|UniProtKB=F6WUB5 F6WUB5 PTHR21527:SF6 NUCLEOPORIN NUP35 NUCLEOPORIN NUP35 lipid binding#GO:0008289;structural molecule activity#GO:0005198;phospholipid binding#GO:0005543;structural constituent of nuclear pore#GO:0017056;binding#GO:0005488 cellular localization#GO:0051641;NLS-bearing protein import into nucleus#GO:0006607;macromolecule localization#GO:0033036;transport#GO:0006810;protein localization to nucleus#GO:0034504;nucleus organization#GO:0006997;nitrogen compound transport#GO:0071705;establishment of protein localization to organelle#GO:0072594;cellular component organization#GO:0016043;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;protein import into nucleus#GO:0006606;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;protein localization to organelle#GO:0033365;nuclear transport#GO:0051169;import into nucleus#GO:0051170 envelope#GO:0031975;nuclear pore#GO:0005643;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear envelope#GO:0005635;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;organelle envelope#GO:0031967;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transporter#PC00227 CIOIN|Ensembl=ENSCING00000014322.2|UniProtKB=F6TZY2 F6TZY2 PTHR10845:SF259 REGULATOR OF G PROTEIN SIGNALING RGS DOMAIN-CONTAINING PROTEIN-RELATED G-protein modulator#PC00022;protein-binding activity modulator#PC00095;GTPase-activating protein#PC00257 CIOIN|Ensembl=ENSCING00000000409.3|UniProtKB=F6SDZ0 F6SDZ0 PTHR18861:SF0 ELKS/RAB6-INTERACTING/CAST PROTEIN BRUCHPILOT, ISOFORM J membrane traffic protein#PC00150 CIOIN|Ensembl=ENSCING00000001656.3|UniProtKB=F6YIL9 F6YIL9 PTHR11787:SF8 RAB GDP-DISSOCIATION INHIBITOR RAB GDP DISSOCIATION INHIBITOR nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234 localization#GO:0051179;vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234;cellular process#GO:0009987;transport#GO:0006810 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 G-protein modulator#PC00022;protein-binding activity modulator#PC00095 CIOIN|Ensembl=ENSCING00000009091.3|UniProtKB=F6QE62 F6QE62 LOC100184221 PTHR12151:SF5 ELECTRON TRANSPORT PROTIN SCO1/SENC FAMILY MEMBER AT19154P cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;respiratory chain complex IV assembly#GO:0008535;mitochondrial respiratory chain complex assembly#GO:0033108;protein-containing complex organization#GO:0043933;organelle organization#GO:0006996;cytochrome complex assembly#GO:0017004;protein-containing complex assembly#GO:0065003;mitochondrial cytochrome c oxidase assembly#GO:0033617;cellular component organization#GO:0016043;mitochondrion organization#GO:0007005;cellular process#GO:0009987 oxidase#PC00175;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000021455.1|UniProtKB=H2XJW9 H2XJW9 PTHR12941:SF10 ER MEMBRANE PROTEIN COMPLEX ER MEMBRANE PROTEIN COMPLEX SUBUNIT 8_9 HOMOLOG membrane protein complex#GO:0098796;endoplasmic reticulum protein-containing complex#GO:0140534;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;EMC complex#GO:0072546;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 CIOIN|Ensembl=ENSCING00000019567.1|UniProtKB=H2XWV8 H2XWV8 PTHR10896:SF65 GALACTOSYLGALACTOSYLXYLOSYLPROTEIN 3-BETA-GLUCURONOSYLTRANSFERASE BETA-1,3-GLUCURONYLTRANSFERASE GALACTOSYLGALACTOSYLXYLOSYLPROTEIN 3-BETA-GLUCURONOSYLTRANSFERASE 3 carbohydrate metabolic process#GO:0005975;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;primary metabolic process#GO:0044238 cytoplasm#GO:0005737;bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;Golgi membrane#GO:0000139;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111 CIOIN|Ensembl=ENSCING00000004673.3|UniProtKB=F6RG85 F6RG85 PTHR10825:SF29 RING FINGER DOMAIN-CONTAINING, POLYCOMB GROUP COMPONENT POLYCOMB GROUP RING FINGER PROTEIN 1 chromatin/chromatin-binding, or -regulatory protein#PC00077;histone modifying enzyme#PC00261 CIOIN|Ensembl=ENSCING00000004894.3|UniProtKB=F7B9G3 F7B9G3 PTHR11848:SF302 TGF-BETA FAMILY TGF-BETA FAMILY PROFILE DOMAIN-CONTAINING PROTEIN molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;cytokine activity#GO:0005125;protein binding#GO:0005515;signaling receptor binding#GO:0005102 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 CIOIN|Ensembl=ENSCING00000015197.2|UniProtKB=F7BAZ7 F7BAZ7 PTHR12372:SF7 PECANEX PROTEIN PECANEX CIOIN|Ensembl=ENSCING00000020477.1|UniProtKB=H2XKV9 H2XKV9 PTHR46460:SF1 METHYLATED-DNA--PROTEIN-CYSTEINE METHYLTRANSFERASE METHYLATED-DNA--PROTEIN-CYSTEINE METHYLTRANSFERASE CIOIN|Ensembl=ENSCING00000021761.1|UniProtKB=H2Y1V2 H2Y1V2 PTHR14369:SF0 SURFEIT LOCUS PROTEIN 6 SURFEIT LOCUS PROTEIN 6 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 cellular component organization or biogenesis#GO:0071840;cellular component biogenesis#GO:0044085;ribosome biogenesis#GO:0042254;cellular process#GO:0009987;ribosomal large subunit biogenesis#GO:0042273;ribosomal small subunit biogenesis#GO:0042274;ribonucleoprotein complex biogenesis#GO:0022613 membrane-enclosed lumen#GO:0031974;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000000773.3|UniProtKB=F6PH90 F6PH90 LOC100183355 PTHR21568:SF0 TRNA PSEUDOURIDINE SYNTHASE PUS10 TRNA PSEUDOURIDINE SYNTHASE PUS10 isomerase activity#GO:0016853;intramolecular transferase activity#GO:0016866;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;tRNA metabolic process#GO:0006399;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;RNA modification#GO:0009451;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;tRNA modification#GO:0006400;primary metabolic process#GO:0044238;pseudouridine synthesis#GO:0001522;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 CIOIN|Ensembl=ENSCING00000014593.2|UniProtKB=F6TNK4 F6TNK4 PTHR24412:SF497 KELCH PROTEIN KELCH-LIKE PROTEIN 18 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000012899.2|UniProtKB=L7N0U7 L7N0U7 PTHR11783:SF43 SULFOTRANSFERASE SULT AMINE SULFOTRANSFERASE-RELATED sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824 cellular metabolic process#GO:0044237;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000002281.3|UniProtKB=F6VFM3 F6VFM3 PTHR11834:SF0 TRANSCRIPTIONAL ENHANCER FACTOR TEF RELATED PROTEIN SCALLOPED sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 CIOIN|Ensembl=ENSCING00000002410.3|UniProtKB=F6XJL4 F6XJL4 LOC100180023 PTHR46989:SF3 USP DOMAIN-CONTAINING PROTEIN USPA DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000009562.3|UniProtKB=F6TKH9 F6TKH9 PTHR11953:SF0 EXOSOME COMPLEX COMPONENT EXOSOME COMPLEX COMPONENT RRP41 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;heterocycle catabolic process#GO:0046700;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular nitrogen compound catabolic process#GO:0044270;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;organic cyclic compound metabolic process#GO:1901360;rRNA metabolic process#GO:0016072;nitrogen compound metabolic process#GO:0006807;organic cyclic compound catabolic process#GO:1901361;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;organic substance catabolic process#GO:1901575;nucleobase-containing compound catabolic process#GO:0034655;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248 RNA metabolism protein#PC00031;exoribonuclease#PC00099 CIOIN|Ensembl=ENSCING00000002999.3|UniProtKB=F6QB99 F6QB99 LOC100187271 PTHR10617:SF107 ELECTRON TRANSFER FLAVOPROTEIN-UBIQUINONE OXIDOREDUCTASE ELECTRON TRANSFER FLAVOPROTEIN-UBIQUINONE OXIDOREDUCTASE, MITOCHONDRIAL electron transfer activity#GO:0009055;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 cellular metabolic process#GO:0044237;electron transport chain#GO:0022900;cellular process#GO:0009987;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000018975.1|UniProtKB=F6W3W9 F6W3W9 PTHR10194:SF146 RAS GTPASE-ACTIVATING PROTEINS RAS GTPASE-ACTIVATING PROTEIN 1 G-protein modulator#PC00022;protein-binding activity modulator#PC00095;GTPase-activating protein#PC00257 Angiogenesis#P00005>RasGAP#P00190;Interleukin signaling pathway#P00036>RasGAP#P00975;EGF receptor signaling pathway#P00018>GAP#P00546;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>Ras#P00886;Angiogenesis#P00005>GAP#P00205;PDGF signaling pathway#P00047>RasGAP#P01152;FGF signaling pathway#P00021>RasGAP#P00646 CIOIN|Ensembl=ENSCING00000007788.3|UniProtKB=F6X3X4 F6X3X4 PTHR45618:SF9 MITOCHONDRIAL DICARBOXYLATE CARRIER-RELATED MITOCHONDRIAL 2-OXOGLUTARATE_MALATE CARRIER PROTEIN transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000021775.1|UniProtKB=F6WKM7 F6WKM7 PTHR35169:SF1 FE2OG DIOXYGENASE DOMAIN-CONTAINING PROTEIN PROLYL 4-HYDROXYLASE ALPHA SUBUNIT FE(2+) 2OG DIOXYGENASE DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000000252.3|UniProtKB=F6SGK9 F6SGK9 LOC100183765 PTHR34253:SF1 PROTEIN LLP HOMOLOG PROTEIN LLP HOMOLOG nucleic acid binding#GO:0003676;basal RNA polymerase II transcription machinery binding#GO:0001099;RNA binding#GO:0003723;protein binding#GO:0005515;basal transcription machinery binding#GO:0001098;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular developmental process#GO:0048869;developmental cell growth#GO:0048588;neuron projection extension#GO:1990138;neurogenesis#GO:0022008;developmental growth involved in morphogenesis#GO:0060560;developmental growth#GO:0048589;cell projection organization#GO:0030030;developmental process#GO:0032502;multicellular organism development#GO:0007275;growth#GO:0040007;cell morphogenesis#GO:0000902;cell projection morphogenesis#GO:0048858;cellular component organization#GO:0016043;cell growth#GO:0016049;nervous system development#GO:0007399;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;cellular anatomical entity morphogenesis#GO:0032989;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;cell differentiation#GO:0030154;system development#GO:0048731;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;neuron differentiation#GO:0030182;multicellular organismal process#GO:0032501;neuron projection morphogenesis#GO:0048812;neuron development#GO:0048666;generation of neurons#GO:0048699;plasma membrane bounded cell projection morphogenesis#GO:0120039 intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000005687.3|UniProtKB=F6XCG6 F6XCG6 LOC100186454 PTHR22840:SF12 WD REPEAT-CONTAINING PROTEIN 36 WD REPEAT-CONTAINING PROTEIN 36 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;small-subunit processome#GO:0032040;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;nuclear lumen#GO:0031981;90S preribosome#GO:0030686;nuclear protein-containing complex#GO:0140513 CIOIN|Ensembl=ENSCING00000023602.1|UniProtKB=H2XJL6 H2XJL6 PTHR43943:SF2 DEHYDROGENASE/REDUCTASE (SDR FAMILY) MEMBER 4 DEHYDROGENASE_REDUCTASE 4 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000020943.1|UniProtKB=H2XK86 H2XK86 LOC100177892 PTHR21258:SF62 DOCKING PROTEIN RELATED INSULIN RECEPTOR SUBSTRATE 1 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000024268.1|UniProtKB=H2XYT8 H2XYT8 PTHR24418:SF384 TYROSINE-PROTEIN KINASE ACTIVATED CDC42 KINASE 1 protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 non-receptor tyrosine protein kinase#PC00168 CIOIN|Ensembl=ENSCING00000009133.3|UniProtKB=F6TJS2 F6TJS2 LOC100184617 PTHR18640:SF5 SOLUTE CARRIER FAMILY 10 MEMBER 7 SODIUM_BILE ACID COTRANSPORTER 7 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000016282.1|UniProtKB=F6YPP1 F6YPP1 PTHR23301:SF0 CHITIN BINDING PERITROPHIN-A CHITIN-BINDING TYPE-2 DOMAIN-CONTAINING PROTEIN-RELATED CIOIN|Ensembl=ENSCING00000003878.2|UniProtKB=F6XGI2 F6XGI2 LOC100184283 PTHR10827:SF52 RETICULOCALBIN IP16409P cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 calmodulin-related#PC00061 CIOIN|Ensembl=ENSCING00000024808.1|UniProtKB=H2XTP7 H2XTP7 PTHR19325:SF567 COMPLEMENT COMPONENT-RELATED SUSHI DOMAIN-CONTAINING SUSHI, VON WILLEBRAND FACTOR TYPE A, EGF AND PENTRAXIN DOMAIN-CONTAINING PROTEIN 1-LIKE complement component#PC00078 CIOIN|Ensembl=ENSCING00000008057.3|UniProtKB=A0A1W5BBA5 A0A1W5BBA5 LOC100186854 PTHR46600:SF1 THAP DOMAIN-CONTAINING THAP DOMAIN-CONTAINING PROTEIN 1 zinc finger transcription factor#PC00244 CIOIN|Ensembl=ENSCING00000008737.3|UniProtKB=F6TMG7 F6TMG7 LOC100176875 PTHR23055:SF70 CALCIUM BINDING PROTEINS EF-HAND DOMAIN-CONTAINING PROTEIN cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488 calmodulin-related#PC00061 CIOIN|Ensembl=ENSCING00000014355.2|UniProtKB=F6TCH6 F6TCH6 PTHR11659:SF0 GLUTAMYL-TRNA GLN AMIDOTRANSFERASE SUBUNIT B MITOCHONDRIAL AND PROKARYOTIC PET112-RELATED GLUTAMYL-TRNA(GLN) AMIDOTRANSFERASE SUBUNIT B, MITOCHONDRIAL catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on RNA#GO:0140098;ligase activity#GO:0016874;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;tRNA metabolic process#GO:0006399;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 ligase#PC00142;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000005576.3|UniProtKB=F6U4L6 F6U4L6 PTHR12131:SF1 ATP-DEPENDENT RNA AND DNA HELICASE ATP-DEPENDENT RNA HELICASE SUPV3L1, MITOCHONDRIAL-RELATED DNA metabolism protein#PC00009 CIOIN|Ensembl=ENSCING00000017603.2|UniProtKB=H2XMK9 H2XMK9 LOC100177532 PTHR23503:SF8 SOLUTE CARRIER FAMILY 2 FACILITATED GLUCOSE TRANSPORTER PROTEIN 1 transmembrane transporter activity#GO:0022857;sugar transmembrane transporter activity#GO:0051119;transporter activity#GO:0005215;carbohydrate transmembrane transporter activity#GO:0015144 localization#GO:0051179;organic substance transport#GO:0071702;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810;cellular process#GO:0009987;carbohydrate transmembrane transport#GO:0034219;carbohydrate transport#GO:0008643 cellular anatomical entity#GO:0110165;membrane#GO:0016020 secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000012184.2|UniProtKB=F6TUA3 F6TUA3 PTHR19143:SF394 FIBRINOGEN/TENASCIN/ANGIOPOEITIN ANGIOPOIETIN-RELATED PROTEIN 3-LIKE external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 CIOIN|Ensembl=ENSCING00000002128.3|UniProtKB=F6WRR0 F6WRR0 zf(c2h2)-35 PTHR24404:SF111 ZINC FINGER PROTEIN GASTRULA ZINC FINGER PROTEIN XLCGF49.1-LIKE-RELATED sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 CIOIN|Ensembl=ENSCING00000024106.1|UniProtKB=H2XLJ5 H2XLJ5 hspa12a PTHR14187:SF46 ALPHA KINASE/ELONGATION FACTOR 2 KINASE HEAT SHOCK 70 KDA PROTEIN 12A CIOIN|Ensembl=ENSCING00000004006.3|UniProtKB=F6VY59 F6VY59 LOC100176859 PTHR33538:SF2 PROTEIN GAMETE EXPRESSED 1 PROTEIN GAMETE EXPRESSED 1 CIOIN|Ensembl=ENSCING00000012990.2|UniProtKB=F6VUE0 F6VUE0 LOC100180472 PTHR12439:SF42 PLACENTAL PROTEIN 11-RELATED ENDORIBONUCLEASE-RELATED catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a nucleic acid#GO:0140640;endonuclease activity#GO:0004519;RNA nuclease activity#GO:0004540;RNA endonuclease activity#GO:0004521 CIOIN|Ensembl=ENSCING00000019987.1|UniProtKB=H2XL17 H2XL17 PTHR16768:SF5 DOWN REGULATED IN RENAL CARCINOMA 1/TU3A FI14214P CIOIN|Ensembl=ENSCING00000019673.1|UniProtKB=H2Y0W9 H2Y0W9 PTHR21663:SF0 HYPOTHETICAL HEAT DOMAIN-CONTAINING HEAT REPEAT-CONTAINING PROTEIN 5B CIOIN|Ensembl=ENSCING00000011949.2|UniProtKB=F6V9Z4 F6V9Z4 LOC100179144 PTHR12953:SF0 MEMBRANE PROTEIN CH1 RELATED SUN DOMAIN-CONTAINING OSSIFICATION FACTOR macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein folding#GO:0006457;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;membrane#GO:0016020;intracellular anatomical structure#GO:0005622 structural protein#PC00211 CIOIN|Ensembl=ENSCING00000019340.1|UniProtKB=H2XUS6 H2XUS6 PTHR46289:SF19 52 KDA REPRESSOR OF THE INHIBITOR OF THE PROTEIN KINASE-LIKE PROTEIN-RELATED ZINC FINGER MYM-TYPE CONTAINING 1 CIOIN|Ensembl=ENSCING00000020914.1|UniProtKB=H2XZC1 H2XZC1 LOC100179691 PTHR13096:SF8 MINA53 MYC INDUCED NUCLEAR ANTIGEN RIBOSOMAL OXYGENASE 1 CIOIN|Ensembl=ENSCING00000021151.1|UniProtKB=H2XWX4 H2XWX4 LOC100183633 PTHR13177:SF4 DEATH-ASSOCIATED PROTEIN 1 GEO09647P1 protein binding#GO:0005515;binding#GO:0005488 negative regulation of cellular metabolic process#GO:0031324;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;regulation of catabolic process#GO:0009894;response to extracellular stimulus#GO:0009991;regulation of biological process#GO:0050789;cellular response to starvation#GO:0009267;apoptotic process#GO:0006915;cell death#GO:0008219;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;cellular response to extracellular stimulus#GO:0031668;cellular response to stimulus#GO:0051716;regulation of autophagy#GO:0010506;negative regulation of cellular catabolic process#GO:0031330;programmed cell death#GO:0012501;cell communication#GO:0007154;negative regulation of metabolic process#GO:0009892;response to nutrient levels#GO:0031667;negative regulation of autophagy#GO:0010507;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;apoptotic signaling pathway#GO:0097190;negative regulation of catabolic process#GO:0009895;response to stress#GO:0006950;cellular response to nutrient levels#GO:0031669;regulation of cellular process#GO:0050794;response to starvation#GO:0042594;biological regulation#GO:0065007;cellular response to external stimulus#GO:0071496;cellular response to amino acid starvation#GO:0034198;cellular response to stress#GO:0033554;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 CIOIN|Ensembl=ENSCING00000004013.3|UniProtKB=F6VAT4 F6VAT4 PTHR11972:SF191 NADPH OXIDASE FAD-BINDING FR-TYPE DOMAIN-CONTAINING PROTEIN oxidoreductase activity, acting on NAD(P)H#GO:0016651;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 cellular metabolic process#GO:0044237;response to stimulus#GO:0050896;response to stress#GO:0006950;cellular process#GO:0009987;defense response#GO:0006952;metabolic process#GO:0008152 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;plasma membrane protein complex#GO:0098797;oxidoreductase complex#GO:1990204;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 oxidase#PC00175;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000019153.1|UniProtKB=H2XLH1 H2XLH1 PTHR19143:SF458 FIBRINOGEN/TENASCIN/ANGIOPOEITIN FIBRINOGEN C-TERMINAL DOMAIN-CONTAINING PROTEIN-RELATED external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 CIOIN|Ensembl=ENSCING00000014015.2|UniProtKB=F6QW72 F6QW72 PTHR12175:SF5 AD039 HT014 THIOREDOXIN FAMILY TRP26 OS03G0795500 PROTEIN oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000004794.3|UniProtKB=F6RF92 F6RF92 PTHR21683:SF3 COILED-COIL DOMAIN-CONTAINING PROTEIN 42 LIKE-2-LIKE-RELATED CILIA AND FLAGELLA ASSOCIATED PROTEIN 100 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 CIOIN|Ensembl=ENSCING00000005384.3|UniProtKB=F7AW07 F7AW07 LOC104265895 PTHR12682:SF11 ARCHEASE PROTEIN ARCHEASE CIOIN|Ensembl=ENSCING00000011827.2|UniProtKB=F6YWD0 F6YWD0 PTHR20903:SF0 PREFOLDIN SUBUNIT 1-RELATED PREFOLDIN SUBUNIT 1 protein binding#GO:0005515;unfolded protein binding#GO:0051082;binding#GO:0005488 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein folding#GO:0006457;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 chaperone#PC00072 CIOIN|Ensembl=ENSCING00000022624.1|UniProtKB=H2XVT6 H2XVT6 PTHR21100:SF9 PREFOLDIN SUBUNIT 4 PREFOLDIN SUBUNIT 4 protein binding#GO:0005515;unfolded protein binding#GO:0051082;binding#GO:0005488 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein folding#GO:0006457;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000003096.3|UniProtKB=F6PKA1 F6PKA1 LOC100175748 PTHR11199:SF0 STROMAL ANTIGEN LD34181P-RELATED protein-containing complex binding#GO:0044877;binding#GO:0005488;chromatin binding#GO:0003682 cellular component organization or biogenesis#GO:0071840;sister chromatid cohesion#GO:0007062;organelle organization#GO:0006996;chromosome organization#GO:0051276;cell cycle process#GO:0022402;cell cycle#GO:0007049;cellular component organization#GO:0016043;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-DNA complex#GO:0032993;chromosome#GO:0005694;chromatin#GO:0000785;cohesin complex#GO:0008278;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 CIOIN|Ensembl=ENSCING00000004142.3|UniProtKB=F6UHS2 F6UHS2 LOC100186749 PTHR23359:SF206 NUCLEOTIDE KINASE UMP-CMP KINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, phosphate group as acceptor#GO:0016776;catalytic activity#GO:0003824;kinase activity#GO:0016301 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 nucleotide kinase#PC00172;kinase#PC00137 De novo pyrimidine ribonucleotides biosythesis#P02740>Uridylate kinase#P02924;De novo purine biosynthesis#P02738>Adenylate kinase#P02896;Salvage pyrimidine ribonucleotides#P02775>Cytidylate kinase#P03153 CIOIN|Ensembl=ENSCING00000019503.1|UniProtKB=H2XVR0 H2XVR0 PTHR22906:SF43 PROPERDIN PROPERDIN CIOIN|Ensembl=ENSCING00000004859.3|UniProtKB=F6YWY7 F6YWY7 PTHR10606:SF44 6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE-2,6-BISPHOSPHATASE 6-PHOSPHOFRUCTO 2-KINASE_FRUCTOSE 2,6-BISPHOSPHATASE LONG FORM hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;transferase activity, transferring phosphorus-containing groups#GO:0016772;sugar-phosphatase activity#GO:0050308;carbohydrate kinase activity#GO:0019200;kinase activity#GO:0016301;phosphoric ester hydrolase activity#GO:0042578 carbohydrate derivative metabolic process#GO:1901135;cellular metabolic process#GO:0044237;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 carbohydrate phosphatase#PC00066;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000004526.3|UniProtKB=F7A9G9 F7A9G9 zf(ring_c6hc)-6 PTHR16004:SF2 RING FINGER PROTEIN 31-RELATED E3 UBIQUITIN-PROTEIN LIGASE LUBEL acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;modification-dependent protein binding#GO:0140030;transferase activity#GO:0016740;ubiquitin-like protein binding#GO:0032182;K63-linked polyubiquitin modification-dependent protein binding#GO:0070530;ubiquitin protein ligase activity#GO:0061630;ubiquitin binding#GO:0043130;ubiquitin-like protein ligase activity#GO:0061659;protein binding#GO:0005515;catalytic activity, acting on a protein#GO:0140096;polyubiquitin modification-dependent protein binding#GO:0031593 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein polyubiquitination#GO:0000209;post-translational protein modification#GO:0043687;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000005553.3|UniProtKB=F6XE75 F6XE75 PTHR24256:SF566 TRYPTASE-RELATED PEPTIDASE S1 DOMAIN-CONTAINING PROTEIN hydrolase activity#GO:0016787;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 serine protease#PC00203;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000011418.2|UniProtKB=F7AX37 F7AX37 PTHR12181:SF12 LIPIN PHOSPHATIDATE PHOSPHATASE hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 lipid metabolic process#GO:0006629;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular lipid metabolic process#GO:0044255;organic substance metabolic process#GO:0071704;primary metabolic process#GO:0044238;metabolic process#GO:0008152 metabolite interconversion enzyme#PC00262;phosphatase#PC00181 CIOIN|Ensembl=ENSCING00000004301.3|UniProtKB=F6TSL2 F6TSL2 PTHR11675:SF126 N-ACETYLGALACTOSAMINYLTRANSFERASE RICIN B LECTIN DOMAIN-CONTAINING PROTEIN transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;UDP-glycosyltransferase activity#GO:0008194 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;protein O-linked glycosylation#GO:0006493;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000013568.2|UniProtKB=F6YBL5 F6YBL5 PTHR19965:SF82 RNA AND EXPORT FACTOR BINDING PROTEIN THO COMPLEX SUBUNIT 4 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 mRNA export from nucleus#GO:0006406;cellular localization#GO:0051641;macromolecule biosynthetic process#GO:0009059;macromolecule localization#GO:0033036;establishment of RNA localization#GO:0051236;macromolecule metabolic process#GO:0043170;transport#GO:0006810;nucleic acid transport#GO:0050657;nitrogen compound transport#GO:0071705;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;mRNA transport#GO:0051028;RNA localization#GO:0006403;localization#GO:0051179;organic substance transport#GO:0071702;nuclear export#GO:0051168;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;RNA transport#GO:0050658;nucleobase-containing compound transport#GO:0015931;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;nuclear transport#GO:0051169;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000014133.1|UniProtKB=A0A1W3JEV5 A0A1W3JEV5 LOC100178387 PTHR10784:SF0 TRANSLATION INITIATION FACTOR 6 EUKARYOTIC TRANSLATION INITIATION FACTOR 6 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;RNA processing#GO:0006396;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;ribosomal large subunit biogenesis#GO:0042273;nucleobase-containing compound metabolic process#GO:0006139;protein-RNA complex assembly#GO:0022618;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;ribosomal large subunit assembly#GO:0000027;ribosome biogenesis#GO:0042254;non-membrane-bounded organelle assembly#GO:0140694;maturation of 5.8S rRNA#GO:0000460;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular component organization#GO:0016043;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;protein-RNA complex organization#GO:0071826;maturation of LSU-rRNA#GO:0000470 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 translation initiation factor#PC00224;translation factor#PC00223 CIOIN|Ensembl=ENSCING00000000429.3|UniProtKB=F7BK08 F7BK08 LOC100177213 PTHR23512:SF3 MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 1 MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 1 CIOIN|Ensembl=ENSCING00000001595.3|UniProtKB=F6UM48 F6UM48 PTHR23359:SF247 NUCLEOTIDE KINASE CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 206 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;phosphotransferase activity, phosphate group as acceptor#GO:0016776 cellular aromatic compound metabolic process#GO:0006725;pyrimidine nucleotide metabolic process#GO:0006220;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;pyrimidine-containing compound metabolic process#GO:0072527;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;nucleoside diphosphate metabolic process#GO:0009132;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 nucleotide kinase#PC00172;kinase#PC00137 CIOIN|Ensembl=ENSCING00000005620.3|UniProtKB=F7AT36 F7AT36 PTHR13768:SF2 SOLUBLE NSF ATTACHMENT PROTEIN SNAP GAMMA-SOLUBLE NSF ATTACHMENT PROTEIN membrane traffic protein#PC00150 CIOIN|Ensembl=ENSCING00000002212.2|UniProtKB=F6ZPY6 F6ZPY6 PTHR19300:SF61 BETA-1,4-GALACTOSYLTRANSFERASE BETA-1,4-N-ACETYLGALACTOSAMINYLTRANSFERASE galactosyltransferase activity#GO:0008378;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 glycosylation#GO:0070085;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000011806.2|UniProtKB=F6S043 F6S043 LOC100185923 PTHR10357:SF179 ALPHA-AMYLASE FAMILY MEMBER NEUTRAL AND BASIC AMINO ACID TRANSPORT PROTEIN RBAT hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 carbohydrate catabolic process#GO:0016052;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carbohydrate metabolic process#GO:0005975;organic substance metabolic process#GO:0071704;primary metabolic process#GO:0044238;metabolic process#GO:0008152 amylase#PC00048;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000001049.3|UniProtKB=F6UP49 F6UP49 PTHR10407:SF15 HUNTINGTIN INTERACTING PROTEIN 1 HUNTINGTIN INTERACTING PROTEIN 1 cytoskeletal protein binding#GO:0008092;small molecule binding#GO:0036094;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;actin filament binding#GO:0051015;phospholipid binding#GO:0005543;phosphatidylinositol phosphate binding#GO:1901981;molecular adaptor activity#GO:0060090;phosphatidylinositol bisphosphate binding#GO:1902936;protein binding#GO:0005515;lipid binding#GO:0008289;clathrin binding#GO:0030276;protein-containing complex binding#GO:0044877;phosphatidylinositol binding#GO:0035091;anion binding#GO:0043168;ion binding#GO:0043167;actin binding#GO:0003779 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;transport#GO:0006810;endocytosis#GO:0006897;protein-containing complex assembly#GO:0065003;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;establishment of localization#GO:0051234;protein-containing complex organization#GO:0043933;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;import into cell#GO:0098657 intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;cortical cytoskeleton#GO:0030863;cellular anatomical entity#GO:0110165;cell cortex#GO:0005938;cell periphery#GO:0071944;cortical actin cytoskeleton#GO:0030864;organelle#GO:0043226;coated vesicle#GO:0030135;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;clathrin-coated vesicle#GO:0030136;actin cytoskeleton#GO:0015629;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856 non-motor actin binding protein#PC00165 CIOIN|Ensembl=ENSCING00000023878.1|UniProtKB=H2XKE2 H2XKE2 PTHR45670:SF1 E3 UBIQUITIN-PROTEIN LIGASE TRIP12 E3 UBIQUITIN-PROTEIN LIGASE HECTD1 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein polyubiquitination#GO:0000209;proteasomal protein catabolic process#GO:0010498;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000009031.3|UniProtKB=F6R7Q8 F6R7Q8 spata4 PTHR12509:SF8 SPERMATOGENESIS-ASSOCIATED 4-RELATED SPERMATOGENESIS-ASSOCIATED PROTEIN 4 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 biological regulation#GO:0065007;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of organelle organization#GO:0033043 axoneme#GO:0005930;cytoplasmic region#GO:0099568;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;plasma membrane bounded cell projection cytoplasm#GO:0032838;ciliary plasm#GO:0097014;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cytoskeleton#GO:0005856;cilium#GO:0005929 CIOIN|Ensembl=ENSCING00000004848.3|UniProtKB=F6TYR4 F6TYR4 PTHR23339:SF115 TYROSINE SPECIFIC PROTEIN PHOSPHATASE AND DUAL SPECIFICITY PROTEIN PHOSPHATASE PROTEIN-TYROSINE-PHOSPHATASE hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;protein tyrosine phosphatase activity#GO:0004725;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 protein phosphatase#PC00195;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000004929.3|UniProtKB=F7AQH5 F7AQH5 LOC100176899 PTHR22974:SF21 MIXED LINEAGE PROTEIN KINASE DUAL SPECIFICITY PROTEIN KINASE TTK transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 negative regulation of sister chromatid segregation#GO:0033046;cellular localization#GO:0051641;regulation of mitotic nuclear division#GO:0007088;regulation of chromosome segregation#GO:0051983;mitotic cell cycle checkpoint signaling#GO:0007093;negative regulation of chromosome organization#GO:2001251;negative regulation of mitotic nuclear division#GO:0045839;regulation of cellular component organization#GO:0051128;negative regulation of nuclear division#GO:0051784;negative regulation of mitotic sister chromatid segregation#GO:0033048;chromosome segregation#GO:0007059;regulation of biological process#GO:0050789;cell cycle checkpoint signaling#GO:0000075;mitotic cell cycle#GO:0000278;nitrogen compound metabolic process#GO:0006807;regulation of mitotic sister chromatid segregation#GO:0033047;reproductive process#GO:0022414;intracellular signal transduction#GO:0035556;negative regulation of cellular component organization#GO:0051129;organic substance metabolic process#GO:0071704;negative regulation of cell cycle#GO:0045786;meiotic cell cycle#GO:0051321;regulation of mitotic cell cycle phase transition#GO:1901990;macromolecule metabolic process#GO:0043170;regulation of organelle organization#GO:0033043;mitotic spindle assembly checkpoint signaling#GO:0007094;negative regulation of chromosome segregation#GO:0051985;regulation of cell cycle phase transition#GO:1901987;cellular metabolic process#GO:0044237;cell communication#GO:0007154;regulation of mitotic metaphase/anaphase transition#GO:0030071;primary metabolic process#GO:0044238;regulation of cell cycle process#GO:0010564;protein localization#GO:0008104;cellular macromolecule localization#GO:0070727;reproduction#GO:0000003;regulation of cellular process#GO:0050794;sexual reproduction#GO:0019953;negative regulation of metaphase/anaphase transition of cell cycle#GO:1902100;negative regulation of mitotic sister chromatid separation#GO:2000816;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;negative regulation of mitotic metaphase/anaphase transition#GO:0045841;macromolecule localization#GO:0033036;macromolecule modification#GO:0043412;regulation of chromosome separation#GO:1905818;cell cycle process#GO:0022402;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;negative regulation of cell cycle process#GO:0010948;peptidyl-serine phosphorylation#GO:0018105;mitotic cell cycle process#GO:1903047;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;negative regulation of mitotic cell cycle phase transition#GO:1901991;protein localization to kinetochore#GO:0034501;meiotic cell cycle process#GO:1903046;negative regulation of organelle organization#GO:0010639;protein localization to organelle#GO:0033365;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;regulation of chromosome organization#GO:0033044;cellular response to stimulus#GO:0051716;regulation of mitotic sister chromatid separation#GO:0010965;regulation of nuclear division#GO:0051783;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;negative regulation of cell cycle phase transition#GO:1901988;organonitrogen compound metabolic process#GO:1901564;negative regulation of mitotic cell cycle#GO:0045930;protein phosphorylation#GO:0006468;cellular process#GO:0009987;localization#GO:0051179;response to stimulus#GO:0050896;negative regulation of chromosome separation#GO:1905819;regulation of meiotic cell cycle#GO:0051445;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;peptidyl-serine modification#GO:0018209;regulation of sister chromatid segregation#GO:0033045;regulation of mitotic cell cycle#GO:0007346 supramolecular complex#GO:0099080;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;kinetochore#GO:0000776;condensed chromosome, centromeric region#GO:0000779;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;chromosomal region#GO:0098687 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000002103.3|UniProtKB=F6ZRX9 F6ZRX9 LOC100181154 PTHR10909:SF382 ELECTRON TRANSPORT OXIDOREDUCTASE ACYL-COENZYME A OXIDASE nucleotide binding#GO:0000166;fatty acid binding#GO:0005504;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;organic cyclic compound binding#GO:0097159;carboxylic acid binding#GO:0031406;nucleoside phosphate binding#GO:1901265;flavin adenine dinucleotide binding#GO:0050660;heterocyclic compound binding#GO:1901363;lipid binding#GO:0008289;anion binding#GO:0043168;ion binding#GO:0043167;organic acid binding#GO:0043177 oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;lipid oxidation#GO:0034440;cellular metabolic process#GO:0044237;homeostatic process#GO:0042592;lipid catabolic process#GO:0016042;lipid modification#GO:0030258;chemical homeostasis#GO:0048878;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;fatty acid catabolic process#GO:0009062;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;fatty acid metabolic process#GO:0006631;small molecule catabolic process#GO:0044282;fatty acid beta-oxidation#GO:0006635;lipid homeostasis#GO:0055088;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;cellular lipid metabolic process#GO:0044255;cellular lipid catabolic process#GO:0044242;carboxylic acid metabolic process#GO:0019752;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;monocarboxylic acid catabolic process#GO:0072329 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;microbody#GO:0042579;membrane-bounded organelle#GO:0043227;peroxisome#GO:0005777;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000012598.2|UniProtKB=F6Y339 F6Y339 ap-2-like1 PTHR10812:SF17 TRANSCRIPTION FACTOR AP-2 TRANSCRIPTION FACTOR AP-2, ISOFORM D sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of cell population proliferation#GO:0042127;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031;general transcription factor#PC00259 CIOIN|Ensembl=ENSCING00000023450.1|UniProtKB=H2Y3Q6 H2Y3Q6 PTHR43757:SF16 AMINOMETHYLTRANSFERASE AMINOMETHYLTRANSFERASE, MITOCHONDRIAL cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 methyltransferase#PC00155 CIOIN|Ensembl=ENSCING00000012950.2|UniProtKB=F6RGI4 F6RGI4 LOC100184231 PTHR11661:SF2 60S RIBOSOMAL PROTEIN L12 LARGE RIBOSOMAL SUBUNIT PROTEIN UL11 structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;structural molecule activity#GO:0005198;rRNA binding#GO:0019843;binding#GO:0005488;organic cyclic compound binding#GO:0097159 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic large ribosomal subunit#GO:0022625;large ribosomal subunit#GO:0015934;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000013000.2|UniProtKB=F6V6U3 F6V6U3 PTHR24256:SF570 TRYPTASE-RELATED CLIP-DOMAIN SERINE PROTEASE hydrolase activity#GO:0016787;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 serine protease#PC00203;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000008893.2|UniProtKB=F6QX34 F6QX34 LOC100181478 PTHR11353:SF94 CHAPERONIN T-COMPLEX PROTEIN 1 SUBUNIT EPSILON protein binding#GO:0005515;unfolded protein binding#GO:0051082;binding#GO:0005488 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein folding#GO:0006457;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 chaperonin#PC00073 CIOIN|Ensembl=ENSCING00000000719.3|UniProtKB=F6Q521 F6Q521 LOC100180959 PTHR12300:SF161 HVA22-LIKE PROTEINS RECEPTOR EXPRESSION-ENHANCING PROTEIN membrane traffic protein#PC00150 CIOIN|Ensembl=ENSCING00000004922.3|UniProtKB=Q5IFL5 Q5IFL5 POU-IV PTHR11636:SF70 POU DOMAIN INHIBITORY POU PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 homeodomain transcription factor#PC00119 CIOIN|Ensembl=ENSCING00000021301.1|UniProtKB=H2Y0I1 H2Y0I1 PTHR24020:SF87 COLLAGEN ALPHA COLLAGEN ALPHA-1(VI) CHAIN-LIKE external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 CIOIN|Ensembl=ENSCING00000022189.1|UniProtKB=H2Y1J2 H2Y1J2 PTHR21650:SF4 MEMBRALIN/KINETOCHORE PROTEIN NUF2 MEMBRALIN positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of protein metabolic process#GO:0051246;regulation of catabolic process#GO:0009894;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of proteasomal protein catabolic process#GO:1901800;regulation of protein catabolic process#GO:0042176;regulation of proteolysis involved in protein catabolic process#GO:1903050;positive regulation of proteolysis#GO:0045862;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;regulation of cellular response to stress#GO:0080135;positive regulation of metabolic process#GO:0009893;positive regulation of biological process#GO:0048518;regulation of proteolysis#GO:0030162;cellular response to stimulus#GO:0051716;response to endoplasmic reticulum stress#GO:0034976;positive regulation of proteolysis involved in protein catabolic process#GO:1903052;regulation of response to endoplasmic reticulum stress#GO:1905897;regulation of response to stress#GO:0080134;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of proteasomal protein catabolic process#GO:0061136;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;response to stress#GO:0006950;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;positive regulation of catabolic process#GO:0009896;cellular response to stress#GO:0033554;positive regulation of protein catabolic process#GO:0045732;regulation of metabolic process#GO:0019222 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-motor microtubule binding protein#PC00166 CIOIN|Ensembl=ENSCING00000001952.3|UniProtKB=F6XTZ6 F6XTZ6 PTHR21713:SF4 NASCENT POLYPEPTIDE ASSOCIATED COMPLEX ALPHA SUBUNIT-RELATED GH09281P-RELATED protein binding#GO:0005515;unfolded protein binding#GO:0051082;binding#GO:0005488 localization#GO:0051179;establishment of protein localization to membrane#GO:0090150;localization within membrane#GO:0051668;protein targeting to membrane#GO:0006612;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;protein localization to membrane#GO:0072657;protein targeting#GO:0006605;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 basic helix-loop-helix transcription factor#PC00055 CIOIN|Ensembl=ENSCING00000007576.3|UniProtKB=F7A4H8 F7A4H8 LOC100175858 PTHR11815:SF1 SUCCINYL-COA SYNTHETASE BETA CHAIN SUCCINATE--COA LIGASE [ADP-FORMING] SUBUNIT BETA, MITOCHONDRIAL ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877 cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;nucleobase-containing compound metabolic process#GO:0006139;energy derivation by oxidation of organic compounds#GO:0015980;phosphorus metabolic process#GO:0006793;tricarboxylic acid cycle#GO:0006099;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;amide metabolic process#GO:0043603;purine nucleotide metabolic process#GO:0006163;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;heterocycle metabolic process#GO:0046483;cellular respiration#GO:0045333;aerobic respiration#GO:0009060;acyl-CoA metabolic process#GO:0006637;generation of precursor metabolites and energy#GO:0006091;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;ribonucleotide metabolic process#GO:0009259;primary metabolic process#GO:0044238;purine ribonucleotide metabolic process#GO:0009150;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ligase#PC00142;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000021638.1|UniProtKB=H2XZ71 H2XZ71 LOC100177641 PTHR11567:SF25 ACID PHOSPHATASE-RELATED PROTEIN FRA10AC1 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 cellular metabolic process#GO:0044237;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;dephosphorylation#GO:0016311;metabolic process#GO:0008152 metabolite interconversion enzyme#PC00262;phosphatase#PC00181 CIOIN|Ensembl=ENSCING00000000050.3|UniProtKB=Q4H2Q6 Q4H2Q6 Ci-Tardbp PTHR48033:SF9 RNA-BINDING (RRM/RBD/RNP MOTIFS) FAMILY PROTEIN TAR DNA-BINDING PROTEIN 43 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of biosynthetic process#GO:0009889;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000007008.3|UniProtKB=F7AEM1 F7AEM1 PTHR45672:SF2 PROTEIN DISULFIDE-ISOMERASE C17H9.14C-RELATED PROTEIN DISULFIDE-ISOMERASE A5 isomerase activity#GO:0016853;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;protein disulfide isomerase activity#GO:0003756 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein folding#GO:0006457;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chaperone#PC00072 CIOIN|Ensembl=ENSCING00000007722.3|UniProtKB=F6ZJ76 F6ZJ76 zf(c2h2)-11 PTHR24404:SF114 ZINC FINGER PROTEIN KLUMPFUSS, ISOFORM B-RELATED C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 CIOIN|Ensembl=ENSCING00000004347.3|UniProtKB=F7BMP3 F7BMP3 LOC100181085 PTHR20855:SF3 ADIPOR/PROGESTIN RECEPTOR-RELATED LD03007P G-protein coupled receptor#PC00021 CIOIN|Ensembl=ENSCING00000012725.2|UniProtKB=F7ASV8 F7ASV8 PTHR12981:SF0 ZINC FINGER PROTEIN-LIKE 1 ZINC FINGER PROTEIN-LIKE 1 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150 CIOIN|Ensembl=ENSCING00000009548.3|UniProtKB=H2XKD1 H2XKD1 PTHR19443:SF16 HEXOKINASE HEXOKINASE TYPE 1-RELATED transferase activity, transferring phosphorus-containing groups#GO:0016772;carbohydrate kinase activity#GO:0019200;transferase activity#GO:0016740;hexokinase activity#GO:0004396;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301 monosaccharide metabolic process#GO:0005996;carbohydrate phosphorylation#GO:0046835;cellular metabolic process#GO:0044237;phosphorylation#GO:0016310;hexose metabolic process#GO:0019318;cellular process#GO:0009987;carbohydrate metabolic process#GO:0005975;glucose metabolic process#GO:0006006;phosphorus metabolic process#GO:0006793;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704 kinase#PC00137 Pentose phosphate pathway#P02762>Hexokinase#P03079;Glycolysis#P00024>Hexokinase#P00677;Fructose galactose metabolism#P02744>Hexokinase#P02966 CIOIN|Ensembl=ENSCING00000011375.2|UniProtKB=F6U831 F6U831 ubf PTHR46318:SF3 UPSTREAM BINDING TRANSCRIPTION FACTOR UPSTREAM BINDING TRANSCRIPTION FACTOR DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 General transcription by RNA polymerase I#P00022>UBF1#P00655 CIOIN|Ensembl=ENSCING00000018281.1|UniProtKB=H2XWY8 H2XWY8 PTHR21027:SF1 TRNA-SPLICING ENDONUCLEASE SUBUNIT SEN54 TRNA-SPLICING ENDONUCLEASE SUBUNIT SEN54 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;tRNA splicing, via endonucleolytic cleavage and ligation#GO:0006388;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 protein-containing complex#GO:0032991;endoribonuclease complex#GO:1902555;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;endonuclease complex#GO:1905348;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622 endoribonuclease#PC00094;RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000013467.2|UniProtKB=F6SDR2 F6SDR2 PTHR23226:SF416 ZINC FINGER AND SCAN DOMAIN-CONTAINING FI01424P C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 CIOIN|Ensembl=ENSCING00000001311.3|UniProtKB=F6WVZ0 F6WVZ0 LOC778757 PTHR10129:SF48 TRANSCRIPTION FACTOR MAF MAF-S, ISOFORM B sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;basic leucine zipper transcription factor#PC00056 CIOIN|Ensembl=ENSCING00000013046.2|UniProtKB=F6T5I8 F6T5I8 PTHR12483:SF115 SOLUTE CARRIER FAMILY 31 COPPER TRANSPORTERS COPPER TRANSPORT PROTEIN secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000014819.2|UniProtKB=F6S9R9 F6S9R9 PTHR19325:SF567 COMPLEMENT COMPONENT-RELATED SUSHI DOMAIN-CONTAINING SUSHI, VON WILLEBRAND FACTOR TYPE A, EGF AND PENTRAXIN DOMAIN-CONTAINING PROTEIN 1-LIKE complement component#PC00078 CIOIN|Ensembl=ENSCING00000000253.3|UniProtKB=F6SGI6 F6SGI6 PTHR46143:SF1 CALPAIN-7 CALPAIN-7 cysteine-type peptidase activity#GO:0008234;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;metabolic process#GO:0008152;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704 Huntington disease#P00029>Calpain#P00788 CIOIN|Ensembl=ENSCING00000019311.1|UniProtKB=H2Y0F6 H2Y0F6 LOC100183101 PTHR41161:SF1 PROTEIN NCBP2AS2 PROTEIN NCBP2AS2 CIOIN|Ensembl=ENSCING00000006377.3|UniProtKB=F7AX33 F7AX33 PTHR16517:SF7 TUBBY-RELATED PROTEIN KING TUBBY scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000006500.3|UniProtKB=F6VHP9 F6VHP9 PTHR11909:SF20 CASEIN KINASE-RELATED CASEIN KINASE I ISOFORM ALPHA transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular process#GO:0009987;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 Wnt signaling pathway#P00057>Casein Kinase 1#P01460;Hedgehog signaling pathway#P00025>Casein kinase I#P00681;Parkinson disease#P00049>Casein kinase I#P01242 CIOIN|Ensembl=ENSCING00000011645.2|UniProtKB=F6ZNF4 F6ZNF4 PTHR18945:SF865 NEUROTRANSMITTER GATED ION CHANNEL NICOTINIC ACETYLCHOLINE RECEPTOR ALPHA7, ISOFORM E ligand-gated ion channel#PC00141;ion channel#PC00133;transporter#PC00227 CIOIN|Ensembl=ENSCING00000013002.2|UniProtKB=F6V6S0 F6V6S0 PTHR21467:SF0 PROTEIN PHOSPHATASE 4 REGULATORY SUBUNIT 4 PPP4R4 SERINE_THREONINE-PROTEIN PHOSPHATASE 4 REGULATORY SUBUNIT 4 protein-binding activity modulator#PC00095;phosphatase modulator#PC00184 CIOIN|Ensembl=ENSCING00000007681.3|UniProtKB=F6T6I0 F6T6I0 LOC100176092 PTHR12411:SF586 CYSTEINE PROTEASE FAMILY C1-RELATED CATHEPSIN L-LIKE cysteine-type peptidase activity#GO:0008234;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197 macromolecule catabolic process#GO:0009057;nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;proteolysis#GO:0006508;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;catabolic process#GO:0009056;organonitrogen compound catabolic process#GO:1901565;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;primary metabolic process#GO:0044238 cytoplasm#GO:0005737;lysosome#GO:0005764;intracellular membrane-bounded organelle#GO:0043231;extracellular region#GO:0005576;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;organelle#GO:0043226;lytic vacuole#GO:0000323;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cysteine protease#PC00081;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000005833.3|UniProtKB=F6VUN5 F6VUN5 PTHR21208:SF1 ADP-DEPENDENT GLUCOKINASE ADP-DEPENDENT GLUCOKINASE carbohydrate metabolic process#GO:0005975;organic substance metabolic process#GO:0071704;primary metabolic process#GO:0044238;metabolic process#GO:0008152 transferase#PC00220;kinase#PC00137;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000021015.1|UniProtKB=H2XJU8 H2XJU8 PTHR46297:SF1 ZINC FINGER CCCH-TYPE WITH G PATCH DOMAIN-CONTAINING PROTEIN ZINC FINGER CCCH-TYPE WITH G PATCH DOMAIN-CONTAINING PROTEIN cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription repressor activity#GO:0001217;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of biosynthetic process#GO:0009890;negative regulation of RNA metabolic process#GO:0051253;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000004849.3|UniProtKB=A0A1W5BE54 A0A1W5BE54 LOC100178024 PTHR22588:SF3 VWFA DOMAIN-CONTAINING PROTEIN VWFA DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000018888.1|UniProtKB=Q4H3D9 Q4H3D9 Ci-HMG20 PTHR46040:SF3 HIGH MOBILITY GROUP PROTEIN 2 HIGH MOBILITY GROUP PROTEIN 2 regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of biosynthetic process#GO:0009889;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000000467.3|UniProtKB=F6YW41 F6YW41 LOC100183350 PTHR23231:SF17 GERM CELL-LESS PROTEIN BTB DOMAIN-CONTAINING PROTEIN ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000001162.3|UniProtKB=F6YTT5 F6YTT5 PTHR11467:SF36 HISTONE H1 HISTONE 24-RELATED nucleosome binding#GO:0031491;nucleic acid binding#GO:0003676;chromatin DNA binding#GO:0031490;binding#GO:0005488;organic cyclic compound binding#GO:0097159;chromatin binding#GO:0003682;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;protein-containing complex binding#GO:0044877 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA metabolic process#GO:0051052;chromosome condensation#GO:0030261;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;cellular process#GO:0009987;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA recombination#GO:0045910;negative regulation of DNA metabolic process#GO:0051053;regulation of DNA recombination#GO:0000018;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 CIOIN|Ensembl=ENSCING00000007889.3|UniProtKB=F6TG24 F6TG24 PTHR10730:SF45 PROCOLLAGEN-LYSINE,2-OXOGLUTARATE 5-DIOXYGENASE/GLYCOSYLTRANSFERASE 25 FAMILY MEMBER PROCOLLAGEN-LYSINE,2-OXOGLUTARATE 5-DIOXYGENASE protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000021735.1|UniProtKB=H2XR45 H2XR45 PTHR16771:SF0 26 PROTEASOME COMPLEX SUBUNIT DSS1 26S PROTEASOME COMPLEX SUBUNIT SEM1 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;double-strand break repair via homologous recombination#GO:0000724;nucleobase-containing compound metabolic process#GO:0006139;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;response to stress#GO:0006950;nitrogen compound metabolic process#GO:0006807;recombinational repair#GO:0000725;cellular response to stress#GO:0033554;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 proteasome complex#GO:0000502;endopeptidase complex#GO:1905369;peptidase complex#GO:1905368;intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;catalytic complex#GO:1902494 protease#PC00190;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000008775.3|UniProtKB=F6SZQ5 F6SZQ5 PTHR44157:SF1 DNAJ HOMOLOG SUBFAMILY C MEMBER 11 DNAJ HOMOLOG SUBFAMILY C MEMBER 11 cellular component organization or biogenesis#GO:0071840;membrane organization#GO:0061024;organelle organization#GO:0006996;cellular component organization#GO:0016043;mitochondrial membrane organization#GO:0007006;mitochondrion organization#GO:0007005;cellular process#GO:0009987;inner mitochondrial membrane organization#GO:0007007 chaperone#PC00072 CIOIN|Ensembl=ENSCING00000010527.3|UniProtKB=F7BBI5 F7BBI5 PTHR10127:SF780 DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING METALLOENDOPEPTIDASE hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000001922.3|UniProtKB=F6PRB0 F6PRB0 LOC101242568 PTHR22906:SF43 PROPERDIN PROPERDIN CIOIN|Ensembl=ENSCING00000018058.1|UniProtKB=H2XU57 H2XU57 rps13 PTHR11885:SF6 RIBOSOMAL PROTEIN S15P/S13E SMALL RIBOSOMAL SUBUNIT PROTEIN US15 structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;structural molecule activity#GO:0005198;binding#GO:0005488;organic cyclic compound binding#GO:0097159;rRNA binding#GO:0019843 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic small ribosomal subunit#GO:0022627;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;small ribosomal subunit#GO:0015935;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;ribosomal subunit#GO:0044391 ribosomal protein#PC00202;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000009654.3|UniProtKB=F7AWI9 F7AWI9 LOC100174994 PTHR28658:SF3 TRANSMEMBRANE PROTEIN 180 TRANSMEMBRANE PROTEIN 180 CIOIN|Ensembl=ENSCING00000005270.3|UniProtKB=F6V899 F6V899 PTHR14167:SF76 SH3 DOMAIN-CONTAINING ENDOPHILIN B, ISOFORM A cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;cellular process#GO:0009987;membrane organization#GO:0061024 cellular anatomical entity#GO:0110165;membrane#GO:0016020 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000008077.3|UniProtKB=F6Z761 F6Z761 PTHR11444:SF1 ASPARTATEAMMONIA/ARGININOSUCCINATE/ADENYLOSUCCINATE LYASE FUMARATE HYDRATASE, MITOCHONDRIAL carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829;catalytic activity#GO:0003824;hydro-lyase activity#GO:0016836 oxoacid metabolic process#GO:0043436;aerobic respiration#GO:0009060;cellular respiration#GO:0045333;dicarboxylic acid metabolic process#GO:0043648;generation of precursor metabolites and energy#GO:0006091;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;carboxylic acid metabolic process#GO:0019752;energy derivation by oxidation of organic compounds#GO:0015980;tricarboxylic acid cycle#GO:0006099;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 lyase#PC00144 TCA cycle#P00051>Fumarase#P01271 CIOIN|Ensembl=ENSCING00000003710.3|UniProtKB=F6XH20 F6XH20 PTHR11132:SF250 SOLUTE CARRIER FAMILY 35 SOLUTE CARRIER FAMILY 35 MEMBER E3 carbohydrate derivative transmembrane transporter activity#GO:1901505;secondary active transmembrane transporter activity#GO:0015291;antiporter activity#GO:0015297;transmembrane transporter activity#GO:0022857;nucleobase-containing compound transmembrane transporter activity#GO:0015932;nucleotide-sugar transmembrane transporter activity#GO:0005338;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215 localization#GO:0051179;cellular process#GO:0009987;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000009424.3|UniProtKB=F6TLE7 F6TLE7 PTHR43108:SF8 N-ACETYLGLUCOSAMINE-6-SULFATASE FAMILY MEMBER SD21168P metabolite interconversion enzyme#PC00262;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000002529.3|UniProtKB=F6XS17 F6XS17 LOC100175874 PTHR12283:SF6 GLUTAMINYL-PEPTIDE CYCLOTRANSFERASE GLUTAMINYL-PEPTIDE CYCLOTRANSFERASE-RELATED cation binding#GO:0043169;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;zinc ion binding#GO:0008270;transition metal ion binding#GO:0046914;metal ion binding#GO:0046872;aminoacyltransferase activity#GO:0016755;ion binding#GO:0043167;catalytic activity, acting on a protein#GO:0140096 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000001147.3|UniProtKB=F6YUA5 F6YUA5 LOC100179492 PTHR23293:SF9 FAD SYNTHETASE-RELATED FMN ADENYLYLTRANSFERASE FAD SYNTHASE adenylyltransferase activity#GO:0070566;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;organophosphate biosynthetic process#GO:0090407;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;nucleobase-containing compound biosynthetic process#GO:0034654;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086 transferase#PC00220;metabolite interconversion enzyme#PC00262 Flavin biosynthesis#P02741>FAD synthetase#P02936 CIOIN|Ensembl=ENSCING00000025018.1|UniProtKB=H2XYP7 H2XYP7 PTHR24372:SF77 GLYCOPROTEIN HORMONE RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 response to organic substance#GO:0010033;positive regulation of adenylate cyclase activity#GO:0045762;regulation of lyase activity#GO:0051339;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;cellular response to stimulus#GO:0051716;regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;cellular response to endogenous stimulus#GO:0071495;cellular response to chemical stimulus#GO:0070887;positive regulation of catalytic activity#GO:0043085;cellular response to organic substance#GO:0071310;regulation of cyclase activity#GO:0031279;positive regulation of molecular function#GO:0044093;cell communication#GO:0007154;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;positive regulation of cyclase activity#GO:0031281;hormone-mediated signaling pathway#GO:0009755;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to endogenous stimulus#GO:0009719;response to hormone#GO:0009725;cellular response to hormone stimulus#GO:0032870;response to chemical#GO:0042221;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of lyase activity#GO:0051349;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 CIOIN|Ensembl=ENSCING00000006502.3|UniProtKB=F6Q0T6 F6Q0T6 LOC100176980 PTHR20893:SF2 LD08641P LD08641P CIOIN|Ensembl=ENSCING00000013665.2|UniProtKB=F6Q301 F6Q301 PTHR21528:SF0 DEHYDRODOLICHYL DIPHOSPHATE SYNTHASE COMPLEX SUBUNIT NUS1 DEHYDRODOLICHYL DIPHOSPHATE SYNTHASE COMPLEX SUBUNIT NUS1 prenyltransferase activity#GO:0004659;transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;macromolecule modification#GO:0043412;alcohol biosynthetic process#GO:0046165;protein modification process#GO:0036211;organic hydroxy compound biosynthetic process#GO:1901617;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;organic hydroxy compound metabolic process#GO:1901615;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein glycosylation#GO:0006486;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;alcohol metabolic process#GO:0006066;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;isoprenoid metabolic process#GO:0006720;isoprenoid biosynthetic process#GO:0008299;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;small molecule biosynthetic process#GO:0044283;cellular lipid metabolic process#GO:0044255;glycosylation#GO:0070085;small molecule metabolic process#GO:0044281 intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 CIOIN|Ensembl=ENSCING00000012955.2|UniProtKB=F6RG08 F6RG08 PTHR46518:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 151 OUTER DYNEIN ARM-DOCKING COMPLEX SUBUNIT 3 cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;outer dynein arm assembly#GO:0036158;cell projection organization#GO:0030030;microtubule cytoskeleton organization#GO:0000226;microtubule-based movement#GO:0007018;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;axoneme assembly#GO:0035082;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031;cilium movement#GO:0003341;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;microtubule bundle formation#GO:0001578;axonemal dynein complex assembly#GO:0070286;cytoskeleton organization#GO:0007010;plasma membrane bounded cell projection assembly#GO:0120031 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;microtubule cytoskeleton#GO:0015630;ciliary basal body#GO:0036064;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;cilium#GO:0005929;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000018699.1|UniProtKB=H2XJV4 H2XJV4 PTHR24373:SF370 SLIT RELATED LEUCINE-RICH REPEAT NEURONAL PROTEIN FISH-LIPS, ISOFORM E external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 transmembrane signal receptor#PC00197 CIOIN|Ensembl=ENSCING00000007773.3|UniProtKB=F6XSL1 F6XSL1 PTHR21646:SF24 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE cysteine protease#PC00081;protease#PC00190 CIOIN|Ensembl=ENSCING00000002303.3|UniProtKB=F6URD6 F6URD6 PTHR11716:SF51 PHOSPHOLIPASE A2 FAMILY MEMBER PHOSPHOLIPASE A2 cation binding#GO:0043169;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;phospholipase A2 activity#GO:0004623;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;lipid binding#GO:0008289;phospholipase activity#GO:0004620;ion binding#GO:0043167;phospholipid binding#GO:0005543 lipid metabolic process#GO:0006629;cellular metabolic process#GO:0044237;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;phospholipid metabolic process#GO:0006644;cellular lipid metabolic process#GO:0044255;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 phospholipase#PC00186 CIOIN|Ensembl=ENSCING00000019361.1|UniProtKB=H2Y3G2 H2Y3G2 LOC100187268 PTHR46107:SF3 DUMPY: SHORTER THAN WILD-TYPE THIOREDOXIN DOMAIN-CONTAINING PROTEIN disulfide oxidoreductase activity#GO:0015036;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 cellular anatomical entity#GO:0110165;endomembrane system#GO:0012505 CIOIN|Ensembl=ENSCING00000011790.2|UniProtKB=H2XQR8 H2XQR8 PTHR46224:SF64 ANKYRIN REPEAT FAMILY PROTEIN IQ MOTIF AND ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 1 CIOIN|Ensembl=ENSCING00000003640.3|UniProtKB=F6TJL2 F6TJL2 PTHR10590:SF4 SODIUM/NUCLEOSIDE COTRANSPORTER SOLUTE CARRIER FAMILY 28 MEMBER 3 carbohydrate derivative transmembrane transporter activity#GO:1901505;secondary active transmembrane transporter activity#GO:0015291;nucleoside transmembrane transporter activity#GO:0005337;transmembrane transporter activity#GO:0022857;symporter activity#GO:0015293;nucleobase-containing compound transmembrane transporter activity#GO:0015932;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215 localization#GO:0051179;organic substance transport#GO:0071702;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;nucleobase-containing compound transport#GO:0015931;transport#GO:0006810;nitrogen compound transport#GO:0071705;cellular process#GO:0009987;carbohydrate derivative transport#GO:1901264 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transporter#PC00227 CIOIN|Ensembl=ENSCING00000013795.2|UniProtKB=F6RDZ8 F6RDZ8 PTHR22168:SF7 TMEM26 PROTEIN TRANSMEMBRANE PROTEIN 26-LIKE CIOIN|Ensembl=ENSCING00000008939.3|UniProtKB=F6Q9M9 F6Q9M9 PTHR11802:SF3 SERINE PROTEASE FAMILY S10 SERINE CARBOXYPEPTIDASE RETINOID-INDUCIBLE SERINE CARBOXYPEPTIDASE hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171;carboxypeptidase activity#GO:0004180 serine protease#PC00203;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000008203.3|UniProtKB=F6PJK7 F6PJK7 LOC100176388 PTHR14186:SF26 INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN-RELATED KAZAL TYPE SERINE PEPTIDASE INHIBITOR DOMAIN 1 biological regulation#GO:0065007;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;regulation of signaling#GO:0023051 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 CIOIN|Ensembl=ENSCING00000002880.3|UniProtKB=F6T0I7 F6T0I7 LOC100175702 PTHR21580:SF28 SHIPPO-1-RELATED BOREALIN N-TERMINAL DOMAIN-CONTAINING PROTEIN-RELATED structural protein#PC00211 CIOIN|Ensembl=ENSCING00000023806.1|UniProtKB=H2XR16 H2XR16 PTHR38926:SF72 F-BOX DOMAIN CONTAINING PROTEIN, EXPRESSED IM:7136021-RELATED CIOIN|Ensembl=ENSCING00000004339.3|UniProtKB=F6U857 F6U857 PTHR21315:SF2 APRATAXIN AND PNK-LIKE FACTOR-RELATED APRATAXIN AND PNK-LIKE FACTOR catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on DNA#GO:0140097;catalytic activity#GO:0003824 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;DNA damage response#GO:0006974;response to stress#GO:0006950;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular response to stress#GO:0033554;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;site of DNA damage#GO:0090734;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;site of double-strand break#GO:0035861;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000009207.3|UniProtKB=F6WNE0 F6WNE0 PTHR13140:SF703 MYOSIN UNCONVENTIONAL MYOSIN-VIIA ISOFORM X1-RELATED microfilament motor activity#GO:0000146;cytoskeletal protein binding#GO:0008092;ATP-dependent activity#GO:0140657;binding#GO:0005488;actin filament binding#GO:0051015;cytoskeletal motor activity#GO:0003774;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779 cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987 microvillus#GO:0005902;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;actin-based cell projection#GO:0098858;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 actin binding motor protein#PC00040 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 CIOIN|Ensembl=ENSCING00000020626.1|UniProtKB=H2XMU8 H2XMU8 PTHR19143:SF394 FIBRINOGEN/TENASCIN/ANGIOPOEITIN ANGIOPOIETIN-RELATED PROTEIN 3-LIKE external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 CIOIN|Ensembl=ENSCING00000019161.1|UniProtKB=H2XYR5 H2XYR5 PTHR23349:SF72 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, TWIST HLH54F sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 basic helix-loop-helix transcription factor#PC00055 CIOIN|Ensembl=ENSCING00000013820.2|UniProtKB=A0A1W2WJD9 A0A1W2WJD9 LOC100175733 PTHR12289:SF41 METAXIN RELATED FAILED AXON CONNECTIONS-RELATED transporter#PC00227 CIOIN|Ensembl=ENSCING00000008201.3|UniProtKB=F6PJL4 F6PJL4 PTHR24346:SF82 MAP/MICROTUBULE AFFINITY-REGULATING KINASE KP78A-RELATED transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;signaling#GO:0023052 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000007234.3|UniProtKB=F6VKC0 F6VKC0 PTHR20917:SF0 PNAS-RELATED CALCIUM LOAD-ACTIVATED CALCIUM CHANNEL calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;metal ion transmembrane transporter activity#GO:0046873;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267;monoatomic ion channel activity#GO:0005216 inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;homeostatic process#GO:0042592;intracellular monoatomic ion homeostasis#GO:0006873;chemical homeostasis#GO:0048878;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;monoatomic ion homeostasis#GO:0050801 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000000979.3|UniProtKB=F7AR28 F7AR28 LOC100182366 PTHR12610:SF12 SINGLE STRANDED DNA BINDING PROTEIN SEQUENCE-SPECIFIC SINGLE-STRANDED DNA-BINDING PROTEIN, ISOFORM D positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of RNA metabolic process#GO:0051254;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA metabolism protein#PC00009 CIOIN|Ensembl=ENSCING00000008877.3|UniProtKB=F6QXL1 F6QXL1 LOC100182584 PTHR46876:SF1 LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 11 LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 11 CIOIN|Ensembl=ENSCING00000000355.3|UniProtKB=F6QQ57 F6QQ57 PTHR14362:SF2 COILED-COIL DOMAIN-CONTAINING PROTEIN 81 COILED-COIL DOMAIN-CONTAINING PROTEIN 81 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000015060.2|UniProtKB=F6RSS5 F6RSS5 PTHR43115:SF4 DEHYDROGENASE/REDUCTASE SDR FAMILY MEMBER 11 DEHYDROGENASE_REDUCTASE SDR FAMILY MEMBER 11 oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000023887.1|UniProtKB=H2XNB4 H2XNB4 LOC100181997 PTHR11071:SF561 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE D-RELATED peptidyl-prolyl cis-trans isomerase activity#GO:0003755;isomerase activity#GO:0016853;catalytic activity, acting on a protein#GO:0140096;binding#GO:0005488;catalytic activity#GO:0003824;peptide binding#GO:0042277;amide binding#GO:0033218 macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein peptidyl-prolyl isomerization#GO:0000413;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein folding#GO:0006457;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 chaperone#PC00072 CIOIN|Ensembl=ENSCING00000021968.1|UniProtKB=H2XNI0 H2XNI0 PTHR24082:SF330 NUCLEAR HORMONE RECEPTOR THYROID HORMONE RECEPTOR BETA cis-regulatory region sequence-specific DNA binding#GO:0000987;signaling receptor activity#GO:0038023;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular transducer activity#GO:0060089;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;hormone-mediated signaling pathway#GO:0009755;regulation of biological process#GO:0050789;cellular response to hormone stimulus#GO:0032870;negative regulation of DNA-templated transcription#GO:0045892;positive regulation of biological process#GO:0048518;cellular developmental process#GO:0048869;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;negative regulation of metabolic process#GO:0009892;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of nitrogen compound metabolic process#GO:0051172;positive regulation of cellular process#GO:0048522;regulation of cellular process#GO:0050794;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;negative regulation of cellular metabolic process#GO:0031324;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;positive regulation of RNA biosynthetic process#GO:1902680;negative regulation of RNA biosynthetic process#GO:1902679;developmental process#GO:0032502;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of biosynthetic process#GO:0009891;cell differentiation#GO:0030154;response to endogenous stimulus#GO:0009719;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;intracellular receptor signaling pathway#GO:0030522;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;negative regulation of biosynthetic process#GO:0009890;regulation of DNA-templated transcription#GO:0006355;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;response to stimulus#GO:0050896;regulation of cellular biosynthetic process#GO:0031326;response to hormone#GO:0009725;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;positive regulation of RNA metabolic process#GO:0051254 C4 zinc finger nuclear receptor#PC00169;zinc finger transcription factor#PC00244 CIOIN|Ensembl=ENSCING00000003633.3|UniProtKB=F7AY24 F7AY24 PTHR10972:SF141 OXYSTEROL-BINDING PROTEIN-RELATED OXYSTEROL-BINDING PROTEIN binding#GO:0005488;organic cyclic compound binding#GO:0097159;steroid binding#GO:0005496;sterol transporter activity#GO:0015248;sterol binding#GO:0032934;lipid binding#GO:0008289;lipid transporter activity#GO:0005319;transporter activity#GO:0005215 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;membrane#GO:0016020;intracellular anatomical structure#GO:0005622 transfer/carrier protein#PC00219 CIOIN|Ensembl=ENSCING00000011831.2|UniProtKB=F6ZLT0 F6ZLT0 LOC100184944 PTHR48208:SF2 CENTROMERE PROTEIN I CENTROMERE PROTEIN I cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;nuclear chromosome segregation#GO:0098813;protein-DNA complex organization#GO:0071824;sister chromatid segregation#GO:0000819;nuclear division#GO:0000280;cell cycle process#GO:0022402;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;protein-DNA complex assembly#GO:0065004;cellular process#GO:0009987;mitotic cell cycle process#GO:1903047;chromosome segregation#GO:0007059;cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;organelle organization#GO:0006996;chromosome organization#GO:0051276;protein-containing complex organization#GO:0043933;cell cycle#GO:0007049;chromatin organization#GO:0006325;mitotic nuclear division#GO:0140014;organelle fission#GO:0048285;mitotic sister chromatid segregation#GO:0000070;chromatin remodeling#GO:0006338 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;kinetochore#GO:0000776;chromosome#GO:0005694;condensed chromosome, centromeric region#GO:0000779;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;chromosomal region#GO:0098687;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000005670.3|UniProtKB=H2XU01 H2XU01 LOC100183719 PTHR46037:SF1 PROTEIN ENHANCER OF SEVENLESS 2B GROWTH FACTOR RECEPTOR-BOUND PROTEIN 2 growth factor receptor binding#GO:0070851;protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of MAPK cascade#GO:0043408;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;regulation of signaling#GO:0023051;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052;regulation of intracellular signal transduction#GO:1902531 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;COP9 signalosome#GO:0008180;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513;plasma membrane#GO:0005886 Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>Grb2#P00892;FGF signaling pathway#P00021>Grb2#P00631;Angiogenesis#P00005>Grb2#P00252;EGF receptor signaling pathway#P00018>Grb2#P00550;PI3 kinase pathway#P00048>Grb2#P01178;Angiogenesis#P00005>Grb2#P00234;PDGF signaling pathway#P00047>Grb2#P01148 CIOIN|Ensembl=ENSCING00000017297.2|UniProtKB=F6UF94 F6UF94 LOC100178501 PTHR46259:SF1 ZINC FINGER CCHC-TYPE AND RNA-BINDING MOTIF-CONTAINING PROTEIN 1 ZINC FINGER CCHC-TYPE AND RNA-BINDING MOTIF-CONTAINING PROTEIN 1 CIOIN|Ensembl=ENSCING00000005272.3|UniProtKB=F6UIE4 F6UIE4 LOC100182553 PTHR10529:SF236 AP COMPLEX SUBUNIT MU AP-2 COMPLEX SUBUNIT MU localization#GO:0051179;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization#GO:0051234;import into cell#GO:0098657;transport#GO:0006810;endocytosis#GO:0006897 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150 CCKR signaling map#P06959>AP2M1#P07067 CIOIN|Ensembl=ENSCING00000008671.3|UniProtKB=F6ZF56 F6ZF56 PTHR13000:SF0 NUCLEOPORIN P54 NUCLEOPORIN P54 structural molecule activity#GO:0005198;structural constituent of nuclear pore#GO:0017056 localization within membrane#GO:0051668;cellular localization#GO:0051641;NLS-bearing protein import into nucleus#GO:0006607;macromolecule localization#GO:0033036;protein localization to membrane#GO:0072657;transport#GO:0006810;protein localization to nucleus#GO:0034504;nucleus organization#GO:0006997;nitrogen compound transport#GO:0071705;establishment of protein localization to organelle#GO:0072594;cellular component organization#GO:0016043;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;protein import into nucleus#GO:0006606;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;protein localization to organelle#GO:0033365;nuclear transport#GO:0051169;import into nucleus#GO:0051170 envelope#GO:0031975;nuclear pore#GO:0005643;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear envelope#GO:0005635;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;organelle envelope#GO:0031967;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transporter#PC00227 CIOIN|Ensembl=ENSCING00000017984.1|UniProtKB=H2Y2E8 H2Y2E8 PTHR10414:SF37 ETHANOLAMINEPHOSPHOTRANSFERASE BB IN A BOXCAR, ISOFORM C transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000007223.3|UniProtKB=F6VL61 F6VL61 LOC100185185 PTHR11772:SF23 ASPARAGINE SYNTHETASE ASPARAGINE SYNTHETASE [GLUTAMINE-HYDROLYZING] ligase activity#GO:0016874;catalytic activity#GO:0003824 organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;proteinogenic amino acid metabolic process#GO:0170039;proteinogenic amino acid biosynthetic process#GO:0170038;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;aspartate family amino acid biosynthetic process#GO:0009067;alpha-amino acid biosynthetic process#GO:1901607;nitrogen compound metabolic process#GO:0006807;amino acid biosynthetic process#GO:0008652;alpha-amino acid metabolic process#GO:1901605;aspartate family amino acid metabolic process#GO:0009066;small molecule biosynthetic process#GO:0044283;L-amino acid biosynthetic process#GO:0170034;carboxylic acid metabolic process#GO:0019752;L-amino acid metabolic process#GO:0170033;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ligase#PC00142;metabolite interconversion enzyme#PC00262 Asparagine and aspartate biosynthesis#P02730>Asparagine synthetase#P02853 CIOIN|Ensembl=ENSCING00000001931.3|UniProtKB=F6ZIM0 F6ZIM0 PTHR12374:SF63 TRANSCRIPTIONAL ADAPTOR 2 ADA2 -RELATED TRANSCRIPTIONAL ADAPTER 2-BETA molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;binding#GO:0005488;chromatin binding#GO:0003682;protein-macromolecule adaptor activity#GO:0030674;transcription coactivator activity#GO:0003713;protein-containing complex binding#GO:0044877 protein-DNA complex organization#GO:0071824;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;cellular component organization#GO:0016043;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;protein-containing complex organization#GO:0043933;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;chromatin remodeling#GO:0006338;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 SAGA-type complex#GO:0070461;histone acetyltransferase complex#GO:0000123;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;acetyltransferase complex#GO:1902493;chromatin#GO:0000785;protein-DNA complex#GO:0032993;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein acetyltransferase complex#GO:0031248;protein-containing complex#GO:0032991;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227 DNA-binding transcription factor#PC00218 CIOIN|Ensembl=ENSCING00000016350.2|UniProtKB=F6VGW8 F6VGW8 PTHR12731:SF1 TRANSLOCON-ASSOCIATED PROTEIN, DELTA SUBUNIT TRANSLOCON-ASSOCIATED PROTEIN SUBUNIT DELTA cellular anatomical entity#GO:0110165;endomembrane system#GO:0012505 CIOIN|Ensembl=ENSCING00000023904.1|UniProtKB=H2XKK8 H2XKK8 LOC100184063 PTHR16501:SF6 TRANSPORT AND GOLGI ORGANIZATION PROTEIN 11 TRANSPORT AND GOLGI ORGANIZATION PROTEIN 11 CIOIN|Ensembl=ENSCING00000005858.3|UniProtKB=F6SHG8 F6SHG8 LOC100176138 PTHR11993:SF10 NADH-UBIQUINONE OXIDOREDUCTASE 49 KDA SUBUNIT NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 2, MITOCHONDRIAL oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000014913.2|UniProtKB=F6QY65 F6QY65 PTHR15131:SF3 SMALL NUCLEAR RNA ACTIVATING COMPLEX, POLYPEPTIDE 1 SNRNA-ACTIVATING PROTEIN COMPLEX SUBUNIT 1 sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 cellular aromatic compound metabolic process#GO:0006725;DNA-templated transcription#GO:0006351;RNA metabolic process#GO:0016070;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;heterocycle metabolic process#GO:0046483;snRNA metabolic process#GO:0016073;transcription by RNA polymerase III#GO:0006383;snRNA transcription by RNA polymerase II#GO:0042795;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;ncRNA transcription#GO:0098781;aromatic compound biosynthetic process#GO:0019438;transcription by RNA polymerase II#GO:0006366 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667 CIOIN|Ensembl=ENSCING00000000478.3|UniProtKB=F6QUA3 F6QUA3 tgm2 PTHR11590:SF81 PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE K-LIKE ISOFORM X4 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000006332.3|UniProtKB=F6PXA9 F6PXA9 PTHR47961:SF12 DNA POLYMERASE THETA, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G05260)-RELATED HELICASE POLQ-LIKE DNA metabolism protein#PC00009 CIOIN|Ensembl=ENSCING00000017388.2|UniProtKB=F6X073 F6X073 PTHR10245:SF15 ENDOTHELIAL DIFFERENTIATION-RELATED FACTOR 1 MULTIPROTEIN BRIDGING FACTOR 1 ENDOTHELIAL DIFFERENTIATION-RELATED FACTOR 1 CIOIN|Ensembl=ENSCING00000013022.2|UniProtKB=A0A1W2WJ91 A0A1W2WJ91 LOC100177458 PTHR48129:SF1 60S RIBOSOMAL PROTEIN L37A LARGE RIBOSOMAL SUBUNIT PROTEIN EL43 ribosomal protein#PC00202;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000008005.2|UniProtKB=F6VHM6 F6VHM6 PTHR15913:SF0 ACID CLUSTER PROTEIN 33 MASPARDIN CIOIN|Ensembl=ENSCING00000002019.3|UniProtKB=F6W6K9 F6W6K9 PTHR21567:SF9 CLASP CLIP-ASSOCIATING PROTEIN cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cellular process#GO:0009987;microtubule-based process#GO:0007017;organelle organization#GO:0006996 supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;cytoplasmic microtubule#GO:0005881;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622 non-motor microtubule binding protein#PC00166 CIOIN|Ensembl=ENSCING00000022673.1|UniProtKB=H2XUU3 H2XUU3 PTHR10658:SF11 PHOSPHATIDYLINOSITOL TRANSFER PROTEIN VIBRATOR, ISOFORM B transporter#PC00227 CIOIN|Ensembl=ENSCING00000003901.3|UniProtKB=F6SN27 F6SN27 LOC100181797 PTHR11727:SF17 DIMETHYLADENOSINE TRANSFERASE DIMETHYLADENOSINE TRANSFERASE 1, MITOCHONDRIAL catalytic activity, acting on RNA#GO:0140098;N-methyltransferase activity#GO:0008170;transcription regulator activity#GO:0140110;transferase activity#GO:0016740;rRNA (adenine) methyltransferase activity#GO:0016433;catalytic activity#GO:0003824;catalytic activity, acting on a rRNA#GO:0140102;catalytic activity, acting on a nucleic acid#GO:0140640;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;rRNA methyltransferase activity#GO:0008649;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;RNA methyltransferase activity#GO:0008173 cellular aromatic compound metabolic process#GO:0006725;DNA-templated transcription#GO:0006351;cellular component biogenesis#GO:0044085;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;RNA modification#GO:0009451;rRNA modification#GO:0000154;mitochondrial gene expression#GO:0140053;RNA processing#GO:0006396;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;mitochondrial transcription#GO:0006390;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;DNA-templated transcription initiation#GO:0006352;ribosome biogenesis#GO:0042254;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;mitochondrial RNA metabolic process#GO:0000959;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular component organization or biogenesis#GO:0071840;rRNA methylation#GO:0031167;nucleic acid metabolic process#GO:0090304;macromolecule methylation#GO:0043414;nucleobase-containing compound biosynthetic process#GO:0034654;methylation#GO:0032259;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;aromatic compound biosynthetic process#GO:0019438;RNA methylation#GO:0001510 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA methyltransferase#PC00033 CIOIN|Ensembl=ENSCING00000004321.3|UniProtKB=F7BNT4 F7BNT4 LOC100175204 PTHR13580:SF9 TGF-BETA INDUCED APOPTOSIS PROTEIN AXIN1 UP-REGULATED 1, ISOFORM A sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000002496.3|UniProtKB=F7AKB5 F7AKB5 PTHR24348:SF65 SERINE/THREONINE-PROTEIN KINASE UNC-51-RELATED SERINE_THREONINE-PROTEIN KINASE ULK3 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 microautophagy#GO:0016237;cellular component biogenesis#GO:0044085;regulation of catabolic process#GO:0009894;macroautophagy#GO:0016236;macromolecule modification#GO:0043412;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;autophagy of mitochondrion#GO:0000422;response to extracellular stimulus#GO:0009991;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;cellular component disassembly#GO:0022411;nitrogen compound metabolic process#GO:0006807;catabolic process#GO:0009056;phosphorylation#GO:0016310;mitochondrion organization#GO:0007005;protein metabolic process#GO:0019538;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular component assembly#GO:0022607;macromolecule metabolic process#GO:0043170;regulation of autophagy#GO:0010506;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cellular component organization#GO:0016043;response to nutrient levels#GO:0031667;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;organelle disassembly#GO:1903008;primary metabolic process#GO:0044238;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;reticulophagy#GO:0061709;response to stress#GO:0006950;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;response to starvation#GO:0042594;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;autophagosome assembly#GO:0000045;piecemeal microautophagy of the nucleus#GO:0034727;autophagy#GO:0006914;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;phagophore assembly site#GO:0000407;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;autophagosome#GO:0005776;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 CIOIN|Ensembl=ENSCING00000002630.3|UniProtKB=F7B2P5 F7B2P5 PTHR24372:SF77 GLYCOPROTEIN HORMONE RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 response to organic substance#GO:0010033;positive regulation of adenylate cyclase activity#GO:0045762;regulation of lyase activity#GO:0051339;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;cellular response to stimulus#GO:0051716;regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;cellular response to endogenous stimulus#GO:0071495;cellular response to chemical stimulus#GO:0070887;positive regulation of catalytic activity#GO:0043085;cellular response to organic substance#GO:0071310;regulation of cyclase activity#GO:0031279;positive regulation of molecular function#GO:0044093;cell communication#GO:0007154;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;positive regulation of cyclase activity#GO:0031281;hormone-mediated signaling pathway#GO:0009755;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to endogenous stimulus#GO:0009719;response to hormone#GO:0009725;cellular response to hormone stimulus#GO:0032870;response to chemical#GO:0042221;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of lyase activity#GO:0051349;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 CIOIN|Ensembl=ENSCING00000024962.1|UniProtKB=H2Y331 H2Y331 PTHR35577:SF2 CYSTEINE-RICH, ACIDIC INTEGRAL MEMBRANE PROTEIN-RELATED DYNEIN HEAVY CHAIN CIOIN|Ensembl=ENSCING00000022969.1|UniProtKB=H2Y1W6 H2Y1W6 PTHR12147:SF22 METALLOPEPTIDASE M28 FAMILY MEMBER ENDOPLASMIC RETICULUM METALLOPEPTIDASE 1 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;metabolic process#GO:0008152;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704 metalloprotease#PC00153;protease#PC00190 CIOIN|Ensembl=ENSCING00000006154.3|UniProtKB=F6SDP7 F6SDP7 PTHR11903:SF39 PROSTAGLANDIN G/H SYNTHASE PROSTAGLANDIN G_H SYNTHASE 2-LIKE oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;dioxygenase activity#GO:0051213 long-chain fatty acid metabolic process#GO:0001676;organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;monocarboxylic acid biosynthetic process#GO:0072330;icosanoid metabolic process#GO:0006690;cellular metabolic process#GO:0044237;icosanoid biosynthetic process#GO:0046456;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;prostaglandin metabolic process#GO:0006693;fatty acid metabolic process#GO:0006631;unsaturated fatty acid metabolic process#GO:0033559;unsaturated fatty acid biosynthetic process#GO:0006636;small molecule biosynthetic process#GO:0044283;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;fatty acid biosynthetic process#GO:0006633;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;neuron projection#GO:0043005;intracellular anatomical structure#GO:0005622 oxygenase#PC00177;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000000461.3|UniProtKB=F6YWB6 F6YWB6 PTHR17972:SF0 NUCLEOLAR RNA-ASSOCIATED PROTEIN NUCLEOLAR PROTEIN 6 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;macromolecule localization#GO:0033036;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;transport#GO:0006810;RNA processing#GO:0006396;nucleic acid transport#GO:0050657;nitrogen compound transport#GO:0071705;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA localization#GO:0006403;organic substance transport#GO:0071702;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;RNA transport#GO:0050658;ribosome biogenesis#GO:0042254;nuclear transport#GO:0051169;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;establishment of RNA localization#GO:0051236;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;nuclear export#GO:0051168;rRNA metabolic process#GO:0016072;nucleocytoplasmic transport#GO:0006913;nucleobase-containing compound transport#GO:0015931;ribonucleoprotein complex biogenesis#GO:0022613;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405 membrane-enclosed lumen#GO:0031974;small-subunit processome#GO:0032040;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;preribosome#GO:0030684;nuclear protein-containing complex#GO:0140513;90S preribosome#GO:0030686 RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000019594.1|UniProtKB=H2Y0B3 H2Y0B3 PTHR23423:SF17 ORGANIC SOLUTE TRANSPORTER-RELATED IP17403P localization#GO:0051179;establishment of localization#GO:0051234;transport#GO:0006810 cellular anatomical entity#GO:0110165;membrane#GO:0016020 transporter#PC00227 CIOIN|Ensembl=ENSCING00000004445.3|UniProtKB=F6XE85 F6XE85 LOC100180692 PTHR43580:SF2 OXIDOREDUCTASE GLYR1-RELATED CYTOKINE-LIKE NUCLEAR FACTOR N-PAC oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000016222.2|UniProtKB=F6ZRG6 F6ZRG6 LOC100180840 PTHR11716:SF106 PHOSPHOLIPASE A2 FAMILY MEMBER PHOSPHOLIPASE A2 A2-ACTITOXIN-UCS2A-LIKE cation binding#GO:0043169;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;phospholipase A2 activity#GO:0004623;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;lipid binding#GO:0008289;phospholipase activity#GO:0004620;ion binding#GO:0043167;phospholipid binding#GO:0005543 lipid metabolic process#GO:0006629;cellular metabolic process#GO:0044237;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;phospholipid metabolic process#GO:0006644;cellular lipid metabolic process#GO:0044255;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 phospholipase#PC00186 CIOIN|Ensembl=ENSCING00000021889.1|UniProtKB=H2XRP2 H2XRP2 LOC100185912 PTHR42861:SF29 CALCIUM-TRANSPORTING ATPASE SECRETORY PATHWAY CALCIUM ATPASE, ISOFORM G calcium ion transmembrane transporter activity#GO:0015085;inorganic molecular entity transmembrane transporter activity#GO:0015318;transmembrane transporter activity#GO:0022857;primary active transmembrane transporter activity#GO:0015399;ATP-dependent activity#GO:0140657;metal ion transmembrane transporter activity#GO:0046873;active monoatomic ion transmembrane transporter activity#GO:0022853;P-type ion transporter activity#GO:0015662;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;ATPase-coupled transmembrane transporter activity#GO:0042626;monoatomic cation transmembrane transporter activity#GO:0008324;monoatomic ion transmembrane transporter activity#GO:0015075;inorganic cation transmembrane transporter activity#GO:0022890;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;calcium ion transmembrane transport#GO:0070588;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;homeostatic process#GO:0042592;monoatomic cation homeostasis#GO:0055080;inorganic ion transmembrane transport#GO:0098660;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;cellular process#GO:0009987;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;calcium ion transport#GO:0006816;monoatomic ion homeostasis#GO:0050801;localization#GO:0051179;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation transport#GO:0006812;transition metal ion transport#GO:0000041;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 primary active transporter#PC00068;transporter#PC00227 CIOIN|Ensembl=ENSCING00000000013.3|UniProtKB=F6WI10 F6WI10 PTHR45935:SF21 PROTEIN ZBED8-RELATED DUF4371 DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000012949.2|UniProtKB=F6RGJ1 F6RGJ1 LOC100186615 PTHR22811:SF59 TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN GOLD DOMAIN-CONTAINING PROTEIN-RELATED endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;Golgi organization#GO:0007030;macromolecule localization#GO:0033036;transport#GO:0006810;endomembrane system organization#GO:0010256;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;organelle organization#GO:0006996;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 COPII-coated ER to Golgi transport vesicle#GO:0030134;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;cellular anatomical entity#GO:0110165;organelle#GO:0043226;coated vesicle#GO:0030135;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;endoplasmic reticulum#GO:0005783;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793 vesicle coat protein#PC00235 CIOIN|Ensembl=ENSCING00000005855.3|UniProtKB=Q4H2Q1 Q4H2Q1 Ci-Tgfbr-Ib PTHR23255:SF71 TRANSFORMING GROWTH FACTOR-BETA RECEPTOR TYPE I AND II RECEPTOR PROTEIN SERINE_THREONINE KINASE transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular response to endogenous stimulus#GO:0071495;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;response to growth factor#GO:0070848;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;response to stimulus#GO:0050896;response to endogenous stimulus#GO:0009719;cellular response to growth factor stimulus#GO:0071363;nitrogen compound metabolic process#GO:0006807;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 receptor complex#GO:0043235;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 serine/threonine protein kinase receptor#PC00205 Wnt signaling pathway#P00057>TGFbetaactivated Kinase-1#P01442;Activin beta signaling pathway#P06210>BABO#P06231;ALP23B signaling pathway#P06209>BABO#P06220;MYO signaling pathway#P06215>BABO#P06310;TGF-beta signaling pathway#P00052>TGFbetareceptor I#P01278;TGF-beta signaling pathway#P00052>TGFbetareceptors#P01283;BMP/activin signaling pathway-drosophila#P06211>TGFbetaR I#P06241;TGF-beta signaling pathway#P00052>TGFbetareceptor II#P01277 CIOIN|Ensembl=ENSCING00000004159.3|UniProtKB=F7BQA9 F7BQA9 LOC100186257 PTHR11679:SF71 VESICLE PROTEIN SORTING-ASSOCIATED SEC1 FAMILY DOMAIN-CONTAINING PROTEIN 2 cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907 membrane trafficking regulatory protein#PC00151 CIOIN|Ensembl=ENSCING00000008123.3|UniProtKB=F6Y2X0 F6Y2X0 gp130-like PTHR23037:SF35 CYTOKINE RECEPTOR FIBRONECTIN TYPE-III DOMAIN-CONTAINING PROTEIN transmembrane signal receptor#PC00197 CIOIN|Ensembl=ENSCING00000002112.3|UniProtKB=A0A1W2WD79 A0A1W2WD79 LOC100178974 PTHR45740:SF17 POLY [ADP-RIBOSE] POLYMERASE POLY [ADP-RIBOSE] POLYMERASE TANKYRASE-2-LIKE transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;pentosyltransferase activity#GO:0016763 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000000311.3|UniProtKB=F6ZFW2 F6ZFW2 LOC100183684 PTHR45744:SF2 TYROSINE AMINOTRANSFERASE TYROSINE AMINOTRANSFERASE transaminase#PC00216 Tyrosine biosynthesis#P02784>Aromatic amino acid aminotransferase#P03213 CIOIN|Ensembl=ENSCING00000019393.1|UniProtKB=H2XSI3 H2XSI3 PTHR23426:SF65 FERREDOXIN/ADRENODOXIN FERREDOXIN-2, MITOCHONDRIAL cellular metabolic process#GO:0044237;electron transport chain#GO:0022900;cellular process#GO:0009987;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152 oxidoreductase#PC00176 Vitamin D metabolism and pathway#P04396>FDX#P04607 CIOIN|Ensembl=ENSCING00000012815.2|UniProtKB=F6WPK3 F6WPK3 LOC100176852 PTHR16255:SF1 REQUIRED FOR MEIOTIC NUCLEAR DIVISION PROTEIN 1 HOMOLOG REQUIRED FOR MEIOTIC NUCLEAR DIVISION PROTEIN 1 HOMOLOG CIOIN|Ensembl=ENSCING00000010123.3|UniProtKB=F6PIE8 F6PIE8 LOC100184440 PTHR45683:SF3 MITOCHONDRIAL NICOTINAMIDE ADENINE DINUCLEOTIDE TRANSPORTER 1-RELATED-RELATED MITOCHONDRIAL FOLATE TRANSPORTER_CARRIER amide transmembrane transporter activity#GO:0042887;nucleobase-containing compound transmembrane transporter activity#GO:0015932;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215;organic acid transmembrane transporter activity#GO:0005342 transmembrane transport#GO:0055085;dicarboxylic acid transport#GO:0006835;organic anion transport#GO:0015711;organic acid transport#GO:0015849;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942;cellular process#GO:0009987;carboxylic acid transmembrane transport#GO:1905039;mitochondrial transport#GO:0006839;amide transport#GO:0042886;localization#GO:0051179;organic substance transport#GO:0071702;establishment of localization#GO:0051234;vitamin transport#GO:0051180;organic acid transmembrane transport#GO:1903825;mitochondrial transmembrane transport#GO:1990542 transporter#PC00227 CIOIN|Ensembl=ENSCING00000019540.1|UniProtKB=F7BHT5 F7BHT5 PTHR11461:SF211 SERINE PROTEASE INHIBITOR, SERPIN GH10112P-RELATED protease inhibitor#PC00191 CIOIN|Ensembl=ENSCING00000009888.3|UniProtKB=F6PV82 F6PV82 PTHR24253:SF176 TRANSMEMBRANE PROTEASE SERINE CORIN, ISOFORM B serine protease#PC00203;protease#PC00190 CIOIN|Ensembl=ENSCING00000017522.2|UniProtKB=H2XR80 H2XR80 PTHR10579:SF172 CALCIUM-ACTIVATED CHLORIDE CHANNEL REGULATOR CALCIUM-ACTIVATED CHLORIDE CHANNEL REGULATOR 4 PRECURSOR-RELATED ion channel#PC00133;transporter#PC00227 CIOIN|Ensembl=ENSCING00000018447.1|UniProtKB=H2XJV8 H2XJV8 PTHR42650:SF1 TAIL-ANCHORED PROTEIN INSERTION RECEPTOR WRB GUIDED ENTRY OF TAIL-ANCHORED PROTEINS FACTOR 1 protein-membrane adaptor activity#GO:0043495;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 protein insertion into ER membrane#GO:0045048;localization within membrane#GO:0051668;cellular localization#GO:0051641;endoplasmic reticulum organization#GO:0007029;macromolecule localization#GO:0033036;membrane organization#GO:0061024;protein localization to membrane#GO:0072657;endomembrane system organization#GO:0010256;cellular component organization#GO:0016043;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of protein localization to membrane#GO:0090150;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;organelle organization#GO:0006996;protein localization to organelle#GO:0033365;protein insertion into membrane#GO:0051205 cytoplasm#GO:0005737;endoplasmic reticulum protein-containing complex#GO:0140534;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000013178.2|UniProtKB=F6YEZ2 F6YEZ2 PTHR23282:SF142 APICAL ENDOSOMAL GLYCOPROTEIN PRECURSOR. MAM DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000022391.1|UniProtKB=H2Y0G9 H2Y0G9 PTHR15653:SF0 STRIATIN CONNECTOR OF KINASE TO AP-1, ISOFORM E CIOIN|Ensembl=ENSCING00000019877.1|UniProtKB=H2Y1B2 H2Y1B2 PTHR47979:SF38 DRAB11-RELATED GH01619P GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;ion binding#GO:0043167;anion binding#GO:0043168 localization#GO:0051179;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization#GO:0051234;transport#GO:0006810 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 small GTPase#PC00208 PDGF signaling pathway#P00047>Ras#P01154 CIOIN|Ensembl=ENSCING00000001918.3|UniProtKB=F7ATN8 F7ATN8 PTHR23138:SF94 RAN BINDING PROTEIN RAN BINDING PROTEIN 1 nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 envelope#GO:0031975;cytoplasm#GO:0005737;nuclear pore#GO:0005643;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear envelope#GO:0005635;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000018425.1|UniProtKB=H2XNP4 H2XNP4 LOC778651 PTHR24416:SF525 TYROSINE-PROTEIN KINASE RECEPTOR INSULIN-LIKE RECEPTOR signaling receptor activity#GO:0038023;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;molecular transducer activity#GO:0060089;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672;transmembrane signaling receptor activity#GO:0004888 signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;positive regulation of cellular metabolic process#GO:0031325;developmental process#GO:0032502;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;regulation of molecular function#GO:0065009;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;positive regulation of phosphorylation#GO:0042327;cellular response to stimulus#GO:0051716;positive regulation of catalytic activity#GO:0043085;multicellular organism development#GO:0007275;positive regulation of phosphorus metabolic process#GO:0010562;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphate metabolic process#GO:0045937;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;multicellular organismal process#GO:0032501;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 receptor complex#GO:0043235;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Insulin/IGF pathway-protein kinase B signaling cascade#P00033>INSR IGF-R IRR#P00895;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>INSR IGF-R IRR#P00885;PI3 kinase pathway#P00048>IR#P01187;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>Insulin IGF#P00882 CIOIN|Ensembl=ENSCING00000024715.1|UniProtKB=H2Y3Q7 H2Y3Q7 PTHR45710:SF26 C-TYPE LECTIN DOMAIN-CONTAINING PROTEIN 180 RH26557P defense/immunity protein#PC00090 CIOIN|Ensembl=ENSCING00000019511.1|UniProtKB=F7A801 F7A801 PTHR45752:SF199 LEUCINE-RICH REPEAT-CONTAINING SUBFAMILY NOT NAMED scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000018020.1|UniProtKB=H2XRI8 H2XRI8 PTHR11176:SF57 BOULE-RELATED PROTEIN BOULE RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000010868.3|UniProtKB=F6WQG9 F6WQG9 PTHR43674:SF2 NITRILASE C965.09-RELATED BETA-UREIDOPROPIONASE hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824 hydrolase#PC00121 Pyrimidine Metabolism#P02771>Beta-Ureidopropionase#P03127 CIOIN|Ensembl=ENSCING00000022799.1|UniProtKB=H2XWJ0 H2XWJ0 PTHR12268:SF14 E3 UBIQUITIN-PROTEIN LIGASE KCMF1 DYSTROPHIN-1 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000009609.3|UniProtKB=F7ADD9 F7ADD9 PTHR24023:SF1112 COLLAGEN ALPHA COL_CUTICLE_N DOMAIN-CONTAINING PROTEIN-RELATED structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;external encapsulating structure organization#GO:0045229;extracellular matrix organization#GO:0030198 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;extracellular region#GO:0005576 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 Integrin signalling pathway#P00034>Collagen#P00922 CIOIN|Ensembl=ENSCING00000005899.3|UniProtKB=F6SHX3 F6SHX3 PTHR24248:SF200 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR 5-HYDROXYTRYPTAMINE RECEPTOR 1B-LIKE ISOFORM X1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of MAPK cascade#GO:0043408;signal transduction#GO:0007165;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;cell communication#GO:0007154;cellular process#GO:0009987;regulation of intracellular signal transduction#GO:1902531;positive regulation of MAPK cascade#GO:0043410;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 CIOIN|Ensembl=ENSCING00000008885.3|UniProtKB=F6QXC2 F6QXC2 PTHR22846:SF2 WD40 REPEAT PROTEIN F-BOX-LIKE_WD REPEAT-CONTAINING PROTEIN EBI molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714;protein-macromolecule adaptor activity#GO:0030674 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;histone deacetylase complex#GO:0000118;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 Wnt signaling pathway#P00057>Ebi#P01453 CIOIN|Ensembl=ENSCING00000008036.3|UniProtKB=F6S5F0 F6S5F0 PTHR24039:SF52 FIBRILLIN-RELATED EGF-LIKE DOMAIN-CONTAINING PROTEIN extracellular matrix structural protein#PC00103 CIOIN|Ensembl=ENSCING00000003891.3|UniProtKB=F6SM21 F6SM21 PTHR24412:SF451 KELCH PROTEIN KELCH-LIKE PROTEIN 20 scaffold/adaptor protein#PC00226 Apoptosis signaling pathway#P00006>Smac/Diablo#P00309 CIOIN|Ensembl=ENSCING00000018030.1|UniProtKB=H2XVP1 H2XVP1 PTHR23140:SF0 RNA PROCESSING PROTEIN LD23810P U2 SNRNP-ASSOCIATED SURP MOTIF-CONTAINING PROTEIN nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031;RNA processing factor#PC00147 CIOIN|Ensembl=ENSCING00000008927.3|UniProtKB=F6QA93 F6QA93 LOC100176440 PTHR23320:SF158 MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MS4A -RELATED CREB-BINDING PROTEIN-LIKE ISOFORM X1 transporter#PC00227 CIOIN|Ensembl=ENSCING00000008072.3|UniProtKB=F6ZPT5 F6ZPT5 LOC100178394 PTHR15537:SF2 F-BOX ONLY PROTEIN 7 F-BOX ONLY PROTEIN 7 CIOIN|Ensembl=ENSCING00000018887.1|UniProtKB=H2Y0V2 H2Y0V2 LOC100186103 PTHR34179:SF1 TUMOR PROTEIN P53-INDUCIBLE PROTEIN 13 TUMOR PROTEIN P53-INDUCIBLE PROTEIN 13 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000019532.1|UniProtKB=Q4H367 Q4H367 Ci-Mlx PTHR15741:SF37 BASIC HELIX-LOOP-HELIX ZIP TRANSCRIPTION FACTOR LD38259P sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218 CIOIN|Ensembl=ENSCING00000011577.2|UniProtKB=F6SPF7 F6SPF7 PTHR10024:SF377 SYNAPTOTAGMIN SYNAPTOTAGMIN-15-LIKE ISOFORM X1 cation binding#GO:0043169;small molecule binding#GO:0036094;binding#GO:0005488;phosphatidylserine binding#GO:0001786;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;protein binding#GO:0005515;clathrin binding#GO:0030276;lipid binding#GO:0008289;ion binding#GO:0043167;phospholipid binding#GO:0005543;SNARE binding#GO:0000149 localization#GO:0051179;regulated exocytosis#GO:0045055;exocytosis#GO:0006887;establishment of localization#GO:0051234;secretion#GO:0046903;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;calcium-ion regulated exocytosis#GO:0017156;export from cell#GO:0140352;secretion by cell#GO:0032940 intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;transport vesicle#GO:0030133;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 membrane trafficking regulatory protein#PC00151 CIOIN|Ensembl=ENSCING00000022721.1|UniProtKB=H2XNZ7 H2XNZ7 LOC100182516 PTHR11210:SF2 RING BOX E3 UBIQUITIN-PROTEIN LIGASE RBX1 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;cullin family protein binding#GO:0097602;protein binding#GO:0005515;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cullin-RING ubiquitin ligase complex#GO:0031461;catalytic complex#GO:1902494;transferase complex#GO:1990234;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000012343.2|UniProtKB=F6ZTS3 F6ZTS3 LOC100184892 PTHR16284:SF13 PROTEIN CDV3 HOMOLOG PROTEIN CDV3 HOMOLOG cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000003689.3|UniProtKB=F6XHQ2 F6XHQ2 PTHR13803:SF4 SEC24-RELATED PROTEIN SECRETORY 24CD, ISOFORM C cation binding#GO:0043169;small molecule binding#GO:0036094;zinc ion binding#GO:0008270;binding#GO:0005488;transition metal ion binding#GO:0046914;metal ion binding#GO:0046872;protein binding#GO:0005515;ion binding#GO:0043167;SNARE binding#GO:0000149 endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;membrane organization#GO:0061024;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;COPII-coated vesicle budding#GO:0090114;establishment of localization in cell#GO:0051649;vesicle organization#GO:0016050;intracellular transport#GO:0046907 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;ER to Golgi transport vesicle membrane#GO:0012507;endoplasmic reticulum exit site#GO:0070971;COPII-coated ER to Golgi transport vesicle#GO:0030134;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;coated vesicle#GO:0030135;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;vesicle coat#GO:0030120;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;transport vesicle membrane#GO:0030658;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;membrane coat#GO:0030117;coated vesicle membrane#GO:0030662;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;transport vesicle#GO:0030133;coated membrane#GO:0048475;cytoplasmic vesicle membrane#GO:0030659;endoplasmic reticulum#GO:0005783 vesicle coat protein#PC00235 CIOIN|Ensembl=ENSCING00000002605.3|UniProtKB=F7B383 F7B383 LOC100180451 PTHR43464:SF19 METHYLTRANSFERASE UBIQUINONE BIOSYNTHESIS O-METHYLTRANSFERASE, MITOCHONDRIAL methyltransferase activity#GO:0008168;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824 methyltransferase#PC00155;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000024339.1|UniProtKB=H2XZ13 H2XZ13 PTHR20920:SF5 RPE-SPONDIN SMB DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000004577.3|UniProtKB=F6XBW4 F6XBW4 LOC104266814 PTHR11711:SF322 ADP RIBOSYLATION FACTOR-RELATED ADP-RIBOSYLATION FACTOR 6 carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167 cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 G-protein#PC00020 Integrin signalling pathway#P00034>Arf6#P00919;Huntington disease#P00029>ARF#P00786 CIOIN|Ensembl=ENSCING00000004093.3|UniProtKB=H2XTB4 H2XTB4 LOC100179591 PTHR28658:SF1 TRANSMEMBRANE PROTEIN 180 MAJOR FACILITATOR SUPERFAMILY DOMAIN CONTAINING 13B CIOIN|Ensembl=ENSCING00000006419.3|UniProtKB=F6QRL6 F6QRL6 PTHR23220:SF122 INTEGRIN ALPHA INTEGRIN ALPHA-PS1 cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;integrin binding#GO:0005178;binding#GO:0005488;signaling receptor binding#GO:0005102 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cell adhesion mediated by integrin#GO:0033627;cell-cell adhesion#GO:0098609;cell communication#GO:0007154;cell adhesion#GO:0007155;cell-substrate adhesion#GO:0031589;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cell-matrix adhesion#GO:0007160;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;integrin-mediated signaling pathway#GO:0007229;biological regulation#GO:0065007;signaling#GO:0023052 receptor complex#GO:0043235;membrane protein complex#GO:0098796;external side of plasma membrane#GO:0009897;cell surface#GO:0009986;protein-containing complex#GO:0032991;plasma membrane signaling receptor complex#GO:0098802;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 cell adhesion molecule#PC00069;integrin#PC00126 Integrin signalling pathway#P00034>Integrin alpha#P00941 CIOIN|Ensembl=ENSCING00000011767.2|UniProtKB=F6T9U4 F6T9U4 PTHR31021:SF1 ADENOMATOSIS POLYPOSIS COLI DOWN-REGULATED 1 CHROMOSOME UNDETERMINED SCAFFOLD_56, WHOLE GENOME SHOTGUN SEQUENCE CIOIN|Ensembl=ENSCING00000024654.1|UniProtKB=H2XTG5 H2XTG5 LOC100179293 PTHR28625:SF1 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 35 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 35 regulation of microtubule-based process#GO:0032886;positive regulation of organelle organization#GO:0010638;regulation of plasma membrane bounded cell projection assembly#GO:0120032;regulation of organelle organization#GO:0033043;regulation of cellular component organization#GO:0051128;regulation of plasma membrane bounded cell projection organization#GO:0120035;positive regulation of cell cycle#GO:0045787;regulation of cilium assembly#GO:1902017;positive regulation of cellular process#GO:0048522;regulation of cell cycle process#GO:0010564;regulation of biological process#GO:0050789;regulation of centrosome cycle#GO:0046605;regulation of cytoskeleton organization#GO:0051493;regulation of cellular process#GO:0050794;regulation of cellular component biogenesis#GO:0044087;positive regulation of cell cycle process#GO:0090068;regulation of cell projection assembly#GO:0060491;regulation of organelle assembly#GO:1902115;regulation of cell projection organization#GO:0031344;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;regulation of centriole replication#GO:0046599;regulation of cell cycle#GO:0051726;positive regulation of cellular component biogenesis#GO:0044089;positive regulation of biological process#GO:0048518;regulation of centrosome duplication#GO:0010824 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;centriole#GO:0005814;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 phosphatase modulator#PC00184 CIOIN|Ensembl=ENSCING00000019051.1|UniProtKB=H2Y178 H2Y178 PTHR11461:SF211 SERINE PROTEASE INHIBITOR, SERPIN GH10112P-RELATED protease inhibitor#PC00191 CIOIN|Ensembl=ENSCING00000007325.3|UniProtKB=F6YKG0 F6YKG0 PTHR21222:SF1 MIT DOMAIN-CONTAINING PROTEIN 1 MIT DOMAIN-CONTAINING PROTEIN 1 CIOIN|Ensembl=ENSCING00000007031.3|UniProtKB=F6ZW95 F6ZW95 LOC100183624 PTHR13465:SF3 UPF0183 PROTEIN PROTEIN BROAD-MINDED organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782;cellular component assembly#GO:0022607;non-motile cilium assembly#GO:1905515;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cell projection organization#GO:0030030;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031 CIOIN|Ensembl=ENSCING00000008999.3|UniProtKB=Q4H2W8 Q4H2W8 Ci-Prox-B PTHR12198:SF0 HOMEOBOX PROTEIN PROSPERO/PROX-1/CEH-26 HOMEOBOX PROTEIN PROSPERO sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 CIOIN|Ensembl=ENSCING00000003686.3|UniProtKB=F6XIK7 F6XIK7 PTHR46257:SF3 TYROSINE-PROTEIN PHOSPHATASE CORKSCREW TYROSINE-PROTEIN PHOSPHATASE CORKSCREW hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;protein tyrosine phosphatase activity#GO:0004725;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;protein binding#GO:0005515;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;peptidyl-tyrosine dephosphorylation#GO:0035335;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;developmental process#GO:0032502;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein dephosphorylation#GO:0006470;cellular metabolic process#GO:0044237;cell communication#GO:0007154;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cell differentiation#GO:0030154;mitotic cell cycle#GO:0000278;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;dephosphorylation#GO:0016311;biological regulation#GO:0065007;cell cycle#GO:0007049;intracellular signal transduction#GO:0035556;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 protein phosphatase#PC00195;protein modifying enzyme#PC00260 FGF signaling pathway#P00021>SHP2#P00647;Interferon-gamma signaling pathway#P00035>PTP#P00960 CIOIN|Ensembl=ENSCING00000021175.1|UniProtKB=H2XWG7 H2XWG7 PTHR12838:SF0 U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 11 U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 11-RELATED membrane-enclosed lumen#GO:0031974;small-subunit processome#GO:0032040;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;nuclear lumen#GO:0031981 RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000008550.3|UniProtKB=F6XP43 F6XP43 PTHR24418:SF447 TYROSINE-PROTEIN KINASE TYROSINE PROTEIN-KINASE SRC-1 protein tyrosine kinase activity#GO:0004713;non-membrane spanning protein tyrosine kinase activity#GO:0004715;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein binding#GO:0005515;catalytic activity, acting on a protein#GO:0140096;signaling receptor binding#GO:0005102;kinase activity#GO:0016301;protein kinase activity#GO:0004672 response to external biotic stimulus#GO:0043207;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;immune response#GO:0006955;developmental process#GO:0032502;cell communication#GO:0007154;cellular process#GO:0009987;defense response to symbiont#GO:0140546;regulation of biological process#GO:0050789;immune system process#GO:0002376;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;cell differentiation#GO:0030154;enzyme-linked receptor protein signaling pathway#GO:0007167;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological process involved in interspecies interaction between organisms#GO:0044419;biological regulation#GO:0065007;innate immune response#GO:0045087;defense response#GO:0006952;signaling#GO:0023052;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169 non-receptor tyrosine protein kinase#PC00168 Parkinson disease#P00049>Src kinase#P01230;Integrin signalling pathway#P00034>Src#P00940 CIOIN|Ensembl=ENSCING00000009126.3|UniProtKB=F6S3G5 F6S3G5 PTHR12563:SF17 GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE DIHYDROXYACETONE PHOSPHATE ACYLTRANSFERASE transferase#PC00220;acyltransferase#PC00042;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000021119.1|UniProtKB=F6RVU9 F6RVU9 PTHR24034:SF209 EGF-LIKE DOMAIN-CONTAINING PROTEIN EGF-LIKE DOMAIN-CONTAINING PROTEIN extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 CIOIN|Ensembl=ENSCING00000015829.2|UniProtKB=F6RVA1 F6RVA1 LOC100180258 PTHR34927:SF1 IQ DOMAIN-CONTAINING PROTEIN K IQ DOMAIN-CONTAINING PROTEIN K CIOIN|Ensembl=ENSCING00000008556.2|UniProtKB=F6XP52 F6XP52 siat4 PTHR46032:SF2 ALPHA-2,3-SIALYLTRANSFERASE ST3GAL I ISOFORM X1 GAL BETA 1,3-GALNAC ALPHA-2,3-SIALYL TRANSFERASE-RELATED transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000020408.1|UniProtKB=H2XWA4 H2XWA4 LOC100187497 PTHR16231:SF4 COMM DOMAIN-CONTAINING PROTEIN 4-8 FAMILY MEMBER COMM DOMAIN-CONTAINING PROTEIN 4 CIOIN|Ensembl=ENSCING00000005750.3|UniProtKB=F6PZI7 F6PZI7 PTHR23349:SF68 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, TWIST FI14601P sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 basic helix-loop-helix transcription factor#PC00055 CIOIN|Ensembl=ENSCING00000017017.2|UniProtKB=F7A0I1 F7A0I1 LOC100176740 PTHR19134:SF527 RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 7 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;protein tyrosine phosphatase activity#GO:0004725;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 protein phosphatase#PC00195;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000009092.3|UniProtKB=F6QE53 F6QE53 LOC100185029 PTHR12825:SF0 BNIP1-RELATED VESICLE TRANSPORT PROTEIN SEC20 localization#GO:0051179;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization#GO:0051234;Golgi vesicle transport#GO:0048193;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;transport#GO:0006810 cytoplasm#GO:0005737;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;SNARE complex#GO:0031201;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000005703.3|UniProtKB=F6WQ28 F6WQ28 LOC100185509 PTHR31367:SF5 CYTOSOLIC 5'-NUCLEOTIDASE 1 FAMILY MEMBER CYTOSOLIC 5'-NUCLEOTIDASE 1A CIOIN|Ensembl=ENSCING00000020658.1|UniProtKB=H2Y288 H2Y288 LOC100181824 PTHR12858:SF1 RIBOSOME BIOGENESIS PROTEIN PRE-RRNA-PROCESSING PROTEIN TSR1 HOMOLOG snoRNA binding#GO:0030515;GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;nucleic acid binding#GO:0003676;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;RNA binding#GO:0003723;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;anion binding#GO:0043168;ion binding#GO:0043167 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;RNA processing#GO:0006396;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;ribosome biogenesis#GO:0042254;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;maturation of SSU-rRNA#GO:0030490;ribosomal small subunit biogenesis#GO:0042274 preribosome, small subunit precursor#GO:0030688;ribonucleoprotein complex#GO:1990904;preribosome#GO:0030684;protein-containing complex#GO:0032991 CIOIN|Ensembl=ENSCING00000022650.1|UniProtKB=H2XS20 H2XS20 LOC100175182 PTHR24031:SF301 RNA HELICASE ATP-DEPENDENT RNA HELICASE DDX18 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;RNA processing#GO:0006396;gene expression#GO:0010467;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;ribosomal large subunit biogenesis#GO:0042273;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;maturation of LSU-rRNA#GO:0000470;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA helicase#PC00032 CIOIN|Ensembl=ENSCING00000002888.3|UniProtKB=A0A1W5B6R5 A0A1W5B6R5 LOC100181185 PTHR13261:SF0 BRCA2 AND CDKN1A INTERACTING PROTEIN BRCA2 AND CDKN1A-INTERACTING PROTEIN membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000012532.2|UniProtKB=F7AV79 F7AV79 PTHR46139:SF3 ALKALINE CERAMIDASE ALKALINE CERAMIDASE lipid metabolic process#GO:0006629;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;lipid catabolic process#GO:0016042;cellular process#GO:0009987;sphingolipid metabolic process#GO:0006665;ceramide metabolic process#GO:0006672;primary metabolic process#GO:0044238;membrane lipid metabolic process#GO:0006643;nitrogen compound metabolic process#GO:0006807;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;cellular lipid metabolic process#GO:0044255;sphingolipid catabolic process#GO:0030149;amide metabolic process#GO:0043603;cellular lipid catabolic process#GO:0044242;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 CIOIN|Ensembl=ENSCING00000021607.1|UniProtKB=H2XRL8 H2XRL8 PTHR13059:SF13 HMG-BOX TRANSCRIPTION FACTOR BBX PROTEIN CAPICUA HOMOLOG sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 HMG box transcription factor#PC00024 CIOIN|Ensembl=ENSCING00000005358.3|UniProtKB=Q4H358 Q4H358 Ci-Nemo-Like PTHR24055:SF484 MITOGEN-ACTIVATED PROTEIN KINASE MITOGEN-ACTIVATED PROTEIN KINASE transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;signaling#GO:0023052 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Wnt signaling pathway#P00057>Nemo-like Kinase#P01449 CIOIN|Ensembl=ENSCING00000004338.3|UniProtKB=F7BMV4 F7BMV4 LOC100184308 PTHR46790:SF1 CENTROMERE PROTEIN N CENTROMERE PROTEIN N membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000005490.3|UniProtKB=F7AUQ0 F7AUQ0 PTHR10037:SF288 VOLTAGE-GATED CATION CHANNEL CALCIUM AND SODIUM SODIUM CHANNEL PROTEIN PARA monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;sodium channel activity#GO:0005272;monoatomic cation transmembrane transporter activity#GO:0008324;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;channel activity#GO:0015267;monoatomic ion channel activity#GO:0005216;inorganic cation transmembrane transporter activity#GO:0022890 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;membrane depolarization#GO:0051899;transport#GO:0006810;regulation of membrane potential#GO:0042391;system process#GO:0003008;action potential#GO:0001508;nervous system process#GO:0050877;cell communication#GO:0007154;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;localization#GO:0051179;sodium ion transport#GO:0006814;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;monoatomic cation transport#GO:0006812;multicellular organismal process#GO:0032501;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;sodium ion transmembrane transport#GO:0035725 membrane protein complex#GO:0098796;sodium channel complex#GO:0034706;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;cation channel complex#GO:0034703;plasma membrane#GO:0005886 transporter#PC00227;voltage-gated ion channel#PC00241 CIOIN|Ensembl=ENSCING00000006306.3|UniProtKB=F6Q4K7 F6Q4K7 PTHR10394:SF3 40S RIBOSOMAL PROTEIN S8 SMALL RIBOSOMAL SUBUNIT PROTEIN ES8 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;maturation of SSU-rRNA#GO:0030490;ribosomal small subunit biogenesis#GO:0042274;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic small ribosomal subunit#GO:0022627;cytosol#GO:0005829;small ribosomal subunit#GO:0015935;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000004230.3|UniProtKB=F6YGI4 F6YGI4 PTHR45706:SF4 TYROSINE-PROTEIN PHOSPHATASE TYROSINE-PROTEIN PHOSPHATASE hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;protein tyrosine phosphatase activity#GO:0004725;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 protein phosphatase#PC00195;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000012650.1|UniProtKB=F6URX9 F6URX9 LOC100184213 PTHR22776:SF97 MARVEL-CONTAINING POTENTIAL LIPID RAFT-ASSOCIATED PROTEIN RE01453P cellular anatomical entity#GO:0110165;membrane#GO:0016020 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000003475.3|UniProtKB=F6UAP7 F6UAP7 PTHR44200:SF1 DNAJ HOMOLOG SUBFAMILY C MEMBER 7 DNAJ HOMOLOG SUBFAMILY C MEMBER 7 chaperone#PC00072 CIOIN|Ensembl=ENSCING00000009875.3|UniProtKB=F6XFB8 F6XFB8 LOC100183890 PTHR15454:SF73 NISCHARIN RELATED DYNEIN AXONEMAL LIGHT CHAIN 1 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000014922.1|UniProtKB=F6Y790 F6Y790 PTHR45704:SF16 RAS-LIKE FAMILY MEMBER 11 RAS-RELATED AND ESTROGEN-REGULATED GROWTH INHIBITOR CIOIN|Ensembl=ENSCING00000010080.3|UniProtKB=Q4H3M1 Q4H3M1 Ci-EphrinA-b PTHR11304:SF29 EPHRIN EPHRIN protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 neuron projection guidance#GO:0097485;signal transduction#GO:0007165;neurogenesis#GO:0022008;cell projection organization#GO:0030030;developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cellular anatomical entity morphogenesis#GO:0032989;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;axon guidance#GO:0007411;anatomical structure morphogenesis#GO:0009653;neuron differentiation#GO:0030182;axonogenesis#GO:0007409;plasma membrane bounded cell projection morphogenesis#GO:0120039;signaling#GO:0023052;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;multicellular organism development#GO:0007275;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;cell communication#GO:0007154;cellular process#GO:0009987;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;neuron projection development#GO:0031175;axon development#GO:0061564;enzyme-linked receptor protein signaling pathway#GO:0007167;cell morphogenesis involved in neuron differentiation#GO:0048667;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 membrane-bound signaling molecule#PC00152;intercellular signal molecule#PC00207 CIOIN|Ensembl=ENSCING00000000827.3|UniProtKB=F6R1S7 F6R1S7 LOC100180277 PTHR21676:SF6 PROTEIN STUM PROTEIN STUM CIOIN|Ensembl=ENSCING00000015295.2|UniProtKB=F6TGC0 F6TGC0 PTHR15710:SF160 E3 UBIQUITIN-PROTEIN LIGASE PRAJA E3 UBIQUITIN-PROTEIN LIGASE RNF181 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000021231.1|UniProtKB=H2XQV4 H2XQV4 PTHR47266:SF31 ENDONUCLEASE-RELATED RNA-DIRECTED DNA POLYMERASE CIOIN|Ensembl=ENSCING00000019865.1|UniProtKB=H2XU41 H2XU41 LOC100175802 PTHR10681:SF128 THIOREDOXIN PEROXIDASE THIOREDOXIN-DEPENDENT PEROXIDE REDUCTASE, MITOCHONDRIAL oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;antioxidant activity#GO:0016209;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;response to stress#GO:0006950;catabolic process#GO:0009056;cellular metabolic process#GO:0044237;homeostatic process#GO:0042592;response to oxidative stress#GO:0006979;cellular process#GO:0009987;cellular response to stress#GO:0033554;cellular homeostasis#GO:0019725;cellular catabolic process#GO:0044248;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 peroxidase#PC00180;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000006586.3|UniProtKB=A0A1W3JW59 A0A1W3JW59 LOC100178586 PTHR12443:SF9 TRANSLOCATION PROTEIN SEC62 TRANSLOCATION PROTEIN SEC62 localization within membrane#GO:0051668;cellular localization#GO:0051641;intracellular protein transmembrane transport#GO:0065002;protein localization to endoplasmic reticulum#GO:0070972;transmembrane transport#GO:0055085;macromolecule localization#GO:0033036;post-translational protein targeting to membrane, translocation#GO:0031204;protein localization to membrane#GO:0072657;transport#GO:0006810;protein transmembrane transport#GO:0071806;protein targeting#GO:0006605;nitrogen compound transport#GO:0071705;protein targeting to ER#GO:0045047;establishment of protein localization to organelle#GO:0072594;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;organic substance transport#GO:0071702;establishment of protein localization to membrane#GO:0090150;post-translational protein targeting to endoplasmic reticulum membrane#GO:0006620;protein targeting to membrane#GO:0006612;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;protein localization to organelle#GO:0033365;establishment of protein localization to endoplasmic reticulum#GO:0072599 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000004860.3|UniProtKB=F6TCC8 F6TCC8 PTHR24256:SF545 TRYPTASE-RELATED INACTIVE SERINE PROTEASE 54 hydrolase activity#GO:0016787;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 serine protease#PC00203;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000000142.3|UniProtKB=H2XZP0 H2XZP0 PTHR19143:SF458 FIBRINOGEN/TENASCIN/ANGIOPOEITIN FIBRINOGEN C-TERMINAL DOMAIN-CONTAINING PROTEIN-RELATED external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 CIOIN|Ensembl=ENSCING00000001229.3|UniProtKB=F6YYF3 F6YYF3 LOC100178185 PTHR14519:SF5 VITAMIN K EPOXIDE REDUCTASE COMPLEX, SUBUNIT 1 VITAMIN K EPOXIDE REDUCTASE COMPLEX SUBUNIT 1-LIKE PROTEIN 1 catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular process#GO:0009987;protein metabolic process#GO:0019538;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000023252.1|UniProtKB=H2Y1D7 H2Y1D7 PTHR13232:SF10 NAD(P)H-HYDRATE EPIMERASE NAD(P)H-HYDRATE EPIMERASE epimerase/racemase#PC00096;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000011372.2|UniProtKB=F6Y011 F6Y011 LOC100186038 PTHR22604:SF105 OXIDOREDUCTASES TRANS-1,2-DIHYDROBENZENE-1,2-DIOL DEHYDROGENASE oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000000723.3|UniProtKB=A0A1W3JEY8 A0A1W3JEY8 LOC100180640 PTHR45699:SF3 60S ACIDIC RIBOSOMAL PROTEIN P0 LARGE RIBOSOMAL SUBUNIT PROTEIN UL10 structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;structural molecule activity#GO:0005198;rRNA binding#GO:0019843;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular component biogenesis#GO:0044085;peptide metabolic process#GO:0006518;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;ribosomal large subunit biogenesis#GO:0042273;translation#GO:0006412;protein-RNA complex assembly#GO:0022618;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;ribosomal large subunit assembly#GO:0000027;ribosome biogenesis#GO:0042254;non-membrane-bounded organelle assembly#GO:0140694;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular component assembly#GO:0022607;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cytoplasmic translation#GO:0002181;cellular component organization#GO:0016043;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;peptide biosynthetic process#GO:0043043;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;ribonucleoprotein complex biogenesis#GO:0022613;protein-RNA complex organization#GO:0071826 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic large ribosomal subunit#GO:0022625;large ribosomal subunit#GO:0015934;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000024559.1|UniProtKB=F6UZ77 F6UZ77 PTHR11482:SF6 ARGININE/DIAMINOPIMELATE/ORNITHINE DECARBOXYLASE ORNITHINE DECARBOXYLASE 1-RELATED lyase activity#GO:0016829;carboxy-lyase activity#GO:0016831;carbon-carbon lyase activity#GO:0016830;catalytic activity#GO:0003824 amine metabolic process#GO:0009308;oxoacid metabolic process#GO:0043436;biogenic amine metabolic process#GO:0006576;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;polyamine metabolic process#GO:0006595;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;alpha-amino acid metabolic process#GO:1901605;polyamine biosynthetic process#GO:0006596;carboxylic acid metabolic process#GO:0019752;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 decarboxylase#PC00089 Ornithine degradation#P02758>Ornithine decarboxylase#P03053 CIOIN|Ensembl=ENSCING00000020672.1|UniProtKB=H2Y2F5 H2Y2F5 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE SSU-1 sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824 cellular metabolic process#GO:0044237;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000020573.1|UniProtKB=H2XYG3 H2XYG3 LOC100176100 PTHR12126:SF11 NADH-UBIQUINONE OXIDOREDUCTASE 39 KDA SUBUNIT-RELATED NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 9, MITOCHONDRIAL protein-containing complex binding#GO:0044877;binding#GO:0005488 cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;ubiquinone biosynthetic process#GO:0006744;small molecule biosynthetic process#GO:0044283;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000022897.1|UniProtKB=H2XY03 H2XY03 PTHR42938:SF22 FORMATE DEHYDROGENASE 1 D-3-PHOSPHOGLYCERATE DEHYDROGENASE oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 Serine glycine biosynthesis#P02776>Phosphoglycerate dehydrogenase#P03160 CIOIN|Ensembl=ENSCING00000008629.3|UniProtKB=F6T1L5 F6T1L5 PTHR11559:SF424 CARBOXYLESTERASE CARBOXYLESTERASE 1D-LIKE ISOFORM X1 esterase#PC00097;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000006812.3|UniProtKB=F6UMK0 F6UMK0 LOC100176264 PTHR24256:SF570 TRYPTASE-RELATED CLIP-DOMAIN SERINE PROTEASE hydrolase activity#GO:0016787;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 serine protease#PC00203;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000012550.2|UniProtKB=F7AB24 F7AB24 PTHR43173:SF19 ABC1 FAMILY PROTEIN AARF DOMAIN-CONTAINING PROTEIN KINASE 1 ATP-binding cassette (ABC) transporter#PC00003;transporter#PC00227 CIOIN|Ensembl=ENSCING00000005057.3|UniProtKB=F7A4J9 F7A4J9 PTHR47368:SF2 NUMB PID DOMAIN-CONTAINING PROTEIN cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000009585.3|UniProtKB=F6SXQ6 F6SXQ6 PTHR46241:SF1 ARMADILLO REPEAT-CONTAINING PROTEIN 4 ARMC4 OUTER DYNEIN ARM-DOCKING COMPLEX SUBUNIT 2 CIOIN|Ensembl=ENSCING00000015443.2|UniProtKB=F6WRW7 F6WRW7 PTHR43969:SF9 GLUTATHIONE S TRANSFERASE D10, ISOFORM A-RELATED GLUTATHIONE S TRANSFERASE D10, ISOFORM A-RELATED glutathione transferase activity#GO:0004364;transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824 sulfur compound metabolic process#GO:0006790;nitrogen compound metabolic process#GO:0006807;peptide metabolic process#GO:0006518;cellular modified amino acid metabolic process#GO:0006575;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular process#GO:0009987;glutathione metabolic process#GO:0006749;amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000021801.1|UniProtKB=H2XMS0 H2XMS0 LOC100178742 PTHR28664:SF4 TIGHT JUNCTION-ASSOCIATED PROTEIN 1 TIGHT JUNCTION-ASSOCIATED PROTEIN 1 tight junction#PC00214 CIOIN|Ensembl=ENSCING00000023880.1|UniProtKB=H2XLT4 H2XLT4 PTHR23024:SF24 ARYLACETAMIDE DEACETYLASE ALPHA_BETA HYDROLASE FOLD-3 DOMAIN-CONTAINING PROTEIN deacetylase#PC00087;metabolite interconversion enzyme#PC00262;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000005308.3|UniProtKB=F7BQ69 F7BQ69 PTHR12864:SF3 RAN BINDING PROTEIN 9-RELATED GLUCOSE-INDUCED DEGRADATION PROTEIN 8 HOMOLOG macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000024843.1|UniProtKB=F6Y7H6 F6Y7H6 PTHR11723:SF17 DNA-BINDING PROTEIN INHIBITOR PROTEIN EXTRA-MACROCHAETAE negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;rhythmic process#GO:0048511;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;regulation of biosynthetic process#GO:0009889;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;cellular developmental process#GO:0048869;circadian rhythm#GO:0007623;negative regulation of biosynthetic process#GO:0009890;regulation of DNA-templated transcription#GO:0006355;negative regulation of metabolic process#GO:0009892;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;circadian regulation of gene expression#GO:0032922;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218 CIOIN|Ensembl=ENSCING00000011666.2|UniProtKB=F6X8W4 F6X8W4 PTHR45620:SF15 PDF RECEPTOR-LIKE PROTEIN-RELATED DIURETIC HORMONE 44 RECEPTOR 1-RELATED signaling receptor activity#GO:0038023;peptide hormone binding#GO:0017046;binding#GO:0005488;peptide binding#GO:0042277;amide binding#GO:0033218;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled peptide receptor activity#GO:0008528;hormone binding#GO:0042562;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 CIOIN|Ensembl=ENSCING00000005047.3|UniProtKB=F6SM68 F6SM68 LOC100182206 PTHR43220:SF18 FAMILY NOT NAMED TRANSMEMBRANE PROTEIN 41B CIOIN|Ensembl=ENSCING00000004775.3|UniProtKB=F6PLQ2 F6PLQ2 PTHR23119:SF51 DISCS LARGE DISKS LARGE 1 TUMOR SUPPRESSOR PROTEIN enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;binding#GO:0005488;kinase binding#GO:0019900 establishment or maintenance of cell polarity#GO:0007163;localization within membrane#GO:0051668;cellular localization#GO:0051641;establishment or maintenance of epithelial cell apical/basal polarity#GO:0045197;macromolecule localization#GO:0033036;protein localization to membrane#GO:0072657;developmental process#GO:0032502;multicellular organism development#GO:0007275;cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987;protein localization#GO:0008104;localization#GO:0051179;embryo development#GO:0009790;cellular macromolecule localization#GO:0070727;anatomical structure development#GO:0048856;establishment or maintenance of apical/basal cell polarity#GO:0035088;multicellular organismal process#GO:0032501;receptor clustering#GO:0043113;establishment or maintenance of bipolar cell polarity#GO:0061245;protein-containing complex localization#GO:0031503 basal plasma membrane#GO:0009925;basolateral plasma membrane#GO:0016323;cell junction#GO:0030054;plasma membrane region#GO:0098590;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;basal part of cell#GO:0045178;membrane#GO:0016020;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000010029.3|UniProtKB=A0A1W3JF81 A0A1W3JF81 LOC100175631 PTHR23430:SF426 HISTONE H2A HISTONE H2A nucleosome binding#GO:0031491;nucleic acid binding#GO:0003676;chromatin DNA binding#GO:0031490;binding#GO:0005488;organic cyclic compound binding#GO:0097159;chromatin binding#GO:0003682;DNA binding#GO:0003677;protein-containing complex binding#GO:0044877 negative regulation of gene expression#GO:0010629;negative regulation of cellular metabolic process#GO:0031324;protein-DNA complex organization#GO:0071824;negative regulation of biological process#GO:0048519;negative regulation of biosynthetic process#GO:0009890;heterochromatin formation#GO:0031507;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;negative regulation of gene expression, epigenetic#GO:0045814;cellular process#GO:0009987;epigenetic regulation of gene expression#GO:0040029;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;negative regulation of macromolecule biosynthetic process#GO:0010558;heterochromatin organization#GO:0070828;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;protein-containing complex organization#GO:0043933;regulation of cellular process#GO:0050794;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;chromatin remodeling#GO:0006338;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 CIOIN|Ensembl=ENSCING00000009792.4|UniProtKB=F6ZSN0 F6ZSN0 LOC100183899 PTHR13460:SF0 FAMILY NOT NAMED MALECTIN cellular anatomical entity#GO:0110165;membrane#GO:0016020 CIOIN|Ensembl=ENSCING00000001392.3|UniProtKB=F6ZBC2 F6ZBC2 LOC100175710 PTHR21588:SF18 COILED-COIL-HELIX-COILED-COIL-HELIX DOMAIN CONTAINING 6 MICOS COMPLEX SUBUNIT MIC19 cellular component organization or biogenesis#GO:0071840;membrane organization#GO:0061024;organelle organization#GO:0006996;cellular component organization#GO:0016043;mitochondrial membrane organization#GO:0007006;mitochondrion organization#GO:0007005;cellular process#GO:0009987;inner mitochondrial membrane organization#GO:0007007 envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial envelope#GO:0005740;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227;mitochondrial protein-containing complex#GO:0098798 CIOIN|Ensembl=ENSCING00000007957.3|UniProtKB=F6Z7L9 F6Z7L9 PTHR11986:SF18 AMINOTRANSFERASE CLASS III ORNITHINE AMINOTRANSFERASE, MITOCHONDRIAL small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;identical protein binding#GO:0042802;heterocyclic compound binding#GO:1901363;protein binding#GO:0005515;ion binding#GO:0043167;anion binding#GO:0043168 transaminase#PC00216 CIOIN|Ensembl=ENSCING00000023464.1|UniProtKB=H2XLP5 H2XLP5 PTHR22702:SF1 PROTEASE-ASSOCIATED DOMAIN-CONTAINING PROTEIN PROTEASE-ASSOCIATED DOMAIN-CONTAINING PROTEIN 1 CIOIN|Ensembl=ENSCING00000003458.3|UniProtKB=F6UAZ6 F6UAZ6 PTHR11615:SF258 NITRATE, FORMATE, IRON DEHYDROGENASE CYTOSOLIC FE-S CLUSTER ASSEMBLY FACTOR CG17683-RELATED dehydrogenase#PC00092;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000003654.3|UniProtKB=F7AXY8 F7AXY8 PTHR19139:SF199 AQUAPORIN TRANSPORTER MIP17260P cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 transporter#PC00227 CIOIN|Ensembl=ENSCING00000015368.2|UniProtKB=F7A5P0 F7A5P0 LOC100179922 PTHR24412:SF497 KELCH PROTEIN KELCH-LIKE PROTEIN 18 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000023277.1|UniProtKB=H2XNL8 H2XNL8 PTHR10763:SF23 CELL DIVISION CONTROL PROTEIN 6-RELATED ORIGIN RECOGNITION COMPLEX SUBUNIT 1 sequence-specific double-stranded DNA binding#GO:1990837;DNA replication origin binding#GO:0003688;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690 cellular aromatic compound metabolic process#GO:0006725;negative regulation of biological process#GO:0048519;signal transduction#GO:0007165;mitotic cell cycle checkpoint signaling#GO:0007093;cell cycle process#GO:0022402;negative regulation of cell cycle process#GO:0010948;nucleobase-containing compound metabolic process#GO:0006139;mitotic cell cycle process#GO:1903047;regulation of biological process#GO:0050789;cell cycle checkpoint signaling#GO:0000075;negative regulation of mitotic cell cycle phase transition#GO:1901991;mitotic cell cycle#GO:0000278;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;DNA-templated DNA replication#GO:0006261;mitotic DNA replication checkpoint signaling#GO:0033314;intracellular signal transduction#GO:0035556;negative regulation of cellular process#GO:0048523;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;regulation of cell cycle G2/M phase transition#GO:1902749;negative regulation of cell cycle G2/M phase transition#GO:1902750;regulation of mitotic cell cycle phase transition#GO:1901990;macromolecule metabolic process#GO:0043170;negative regulation of cell cycle#GO:0045786;regulation of cell cycle phase transition#GO:1901987;negative regulation of cell cycle phase transition#GO:1901988;cellular metabolic process#GO:0044237;cell communication#GO:0007154;negative regulation of mitotic cell cycle#GO:0045930;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;regulation of cell cycle process#GO:0010564;response to stimulus#GO:0050896;DNA integrity checkpoint signaling#GO:0031570;nucleic acid metabolic process#GO:0090304;negative regulation of G2/M transition of mitotic cell cycle#GO:0010972;DNA replication checkpoint signaling#GO:0000076;regulation of cellular process#GO:0050794;mitotic G2/M transition checkpoint#GO:0044818;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;regulation of G2/M transition of mitotic cell cycle#GO:0010389;mitotic DNA integrity checkpoint signaling#GO:0044774;DNA replication#GO:0006260;DNA replication initiation#GO:0006270;regulation of mitotic cell cycle#GO:0007346;DNA metabolic process#GO:0006259 origin recognition complex#GO:0000808;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;nuclear origin of replication recognition complex#GO:0005664;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 DNA metabolism protein#PC00009;replication origin binding protein#PC00199 CIOIN|Ensembl=ENSCING00000019669.1|UniProtKB=H2XX08 H2XX08 PTHR45632:SF3 LD33804P KELCH-LIKE PROTEIN 32 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000005033.3|UniProtKB=F6SM76 F6SM76 PTHR42884:SF31 PROPROTEIN CONVERTASE SUBTILISIN/KEXIN-RELATED PROPROTEIN CONVERTASE SUBTILISIN_KEXIN TYPE 5 hydrolase activity#GO:0016787;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;regulation of hormone levels#GO:0010817;cellular process#GO:0009987;protein processing#GO:0016485;primary metabolic process#GO:0044238;hormone metabolic process#GO:0042445;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;biological regulation#GO:0065007;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 bounding membrane of organelle#GO:0098588;trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791;Golgi membrane#GO:0000139 serine protease#PC00203;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000008819.3|UniProtKB=F7BJ31 F7BJ31 LOC100184680 PTHR31553:SF1 NF-KAPPA-B ESSENTIAL MODULATOR NF-KAPPA-B ESSENTIAL MODULATOR protein binding#GO:0005515;K63-linked polyubiquitin modification-dependent protein binding#GO:0070530;binding#GO:0005488;polyubiquitin modification-dependent protein binding#GO:0031593;modification-dependent protein binding#GO:0140030 regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;regulation of canonical NF-kappaB signal transduction#GO:0043122;regulation of signaling#GO:0023051;biological regulation#GO:0065007;regulation of intracellular signal transduction#GO:1902531 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000003683.3|UniProtKB=F6ZUK5 F6ZUK5 PTHR46514:SF3 AMPHIPHYSIN AMPHIPHYSIN lipid binding#GO:0008289;phospholipid binding#GO:0005543;binding#GO:0005488 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 CIOIN|Ensembl=ENSCING00000013662.2|UniProtKB=F6TNP4 F6TNP4 PTHR15036:SF56 PIKACHURIN-LIKE PROTEIN KON-TIKI, ISOFORM B cell adhesion molecule#PC00069 CIOIN|Ensembl=ENSCING00000008690.3|UniProtKB=F6WZZ7 F6WZZ7 PTHR11920:SF494 GUANYLYL CYCLASE ATRIAL NATRIURETIC PEPTIDE RECEPTOR 2 adenylate cyclase activity#GO:0004016;signaling receptor activity#GO:0038023;cyclase activity#GO:0009975;phosphorus-oxygen lyase activity#GO:0016849;catalytic activity#GO:0003824;lyase activity#GO:0016829;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653 cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;signal transduction#GO:0007165;cyclic nucleotide metabolic process#GO:0009187;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;signaling#GO:0023052;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cell communication#GO:0007154;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;response to stimulus#GO:0050896;ribonucleotide biosynthetic process#GO:0009260;enzyme-linked receptor protein signaling pathway#GO:0007167;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;cGMP biosynthetic process#GO:0006182;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 guanylate cyclase#PC00114 Gonadotropin-releasing hormone receptor pathway#P06664>Npr2#P06796;Endothelin signaling pathway#P00019>Guanylate cyclase#P00581 CIOIN|Ensembl=ENSCING00000019527.1|UniProtKB=H2Y236 H2Y236 PTHR36978:SF4 P-LOOP CONTAINING NUCLEOTIDE TRIPHOSPHATE HYDROLASE P-LOOP CONTAINING NUCLEOSIDE TRIPHOSPHATE HYDROLASE PROTEIN metabolite interconversion enzyme#PC00262;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000000707.3|UniProtKB=F6Q5E4 F6Q5E4 PTHR11668:SF300 SERINE/THREONINE PROTEIN PHOSPHATASE SERINE_THREONINE-PROTEIN PHOSPHATASE hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;protein serine/threonine phosphatase activity#GO:0004722;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein phosphatase#PC00195;protein modifying enzyme#PC00260 Nicotine pharmacodynamics pathway#P06587>PPP1CA#P06602;Dopamine receptor mediated signaling pathway#P05912>Protein Phosphatase-1#P05969 CIOIN|Ensembl=ENSCING00000011623.2|UniProtKB=F7AGV8 F7AGV8 PTHR13539:SF3 CALMODULIN-LYSINE N-METHYLTRANSFERASE CALMODULIN-LYSINE N-METHYLTRANSFERASE protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000003474.3|UniProtKB=F6UAV0 F6UAV0 LOC100181148 PTHR19957:SF139 SYNTAXIN SYNTAXIN-17 molecular adaptor activity#GO:0060090;protein binding#GO:0005515;SNAP receptor activity#GO:0005484;binding#GO:0005488;SNARE binding#GO:0000149;protein-macromolecule adaptor activity#GO:0030674 vesicle fusion#GO:0006906;cellular localization#GO:0051641;organelle localization#GO:0051640;macromolecule localization#GO:0033036;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;membrane fusion#GO:0061025;exocytosis#GO:0006887;establishment of localization#GO:0051234;organelle organization#GO:0006996;secretion#GO:0046903;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;vesicle organization#GO:0016050;intracellular transport#GO:0046907;export from cell#GO:0140352;secretion by cell#GO:0032940;organelle fusion#GO:0048284 cytoplasm#GO:0005737;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;SNARE complex#GO:0031201;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 SNARE protein#PC00034;membrane traffic protein#PC00150 CIOIN|Ensembl=ENSCING00000003459.3|UniProtKB=A0A1W2WF05 A0A1W2WF05 LOC100186746 PTHR12866:SF2 UBIQUITIN-LIKE-CONJUGATING ENZYME ATG3 UBIQUITIN-LIKE-CONJUGATING ENZYME ATG3 ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;macroautophagy#GO:0016236;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;autophagy of mitochondrion#GO:0000422;cellular process#GO:0009987;organelle disassembly#GO:1903008;organelle assembly#GO:0070925;process utilizing autophagic mechanism#GO:0061919;cellular component organization or biogenesis#GO:0071840;vacuole organization#GO:0007033;cellular component disassembly#GO:0022411;organelle organization#GO:0006996;autophagosome assembly#GO:0000045;catabolic process#GO:0009056;mitochondrion organization#GO:0007005;autophagy#GO:0006914;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;phagophore assembly site#GO:0000407;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000007837.3|UniProtKB=F6WSZ7 F6WSZ7 PTHR12948:SF3 NEDD8 ULTIMATE BUSTER-1 BS4 PROTEIN NEDD8 ULTIMATE BUSTER 1 regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of proteolysis#GO:0030162;regulation of catabolic process#GO:0009894;regulation of protein metabolic process#GO:0051246;regulation of macromolecule metabolic process#GO:0060255;regulation of nitrogen compound metabolic process#GO:0051171;biological regulation#GO:0065007;regulation of proteolysis involved in protein catabolic process#GO:1903050;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;regulation of metabolic process#GO:0019222 CIOIN|Ensembl=ENSCING00000009185.3|UniProtKB=F6YM02 F6YM02 LOC100181968 PTHR10882:SF0 DIPHTHINE SYNTHASE DIPHTHINE METHYL ESTER SYNTHASE methyltransferase#PC00155 CIOIN|Ensembl=ENSCING00000006267.3|UniProtKB=F6V276 F6V276 PTHR19282:SF551 TETRASPANIN RE08073P-RELATED cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000012555.2|UniProtKB=F7AAW0 F7AAW0 LOC100187300 PTHR45752:SF187 LEUCINE-RICH REPEAT-CONTAINING LEUCINE-RICH REPEAT AND IQ DOMAIN-CONTAINING PROTEIN 4 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000008022.3|UniProtKB=F6TF50 F6TF50 PTHR14017:SF1 LYSINE-SPECIFIC DEMETHYLASE LD02225P cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;chromatin DNA binding#GO:0031490;binding#GO:0005488;organic cyclic compound binding#GO:0097159;chromatin binding#GO:0003682;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;protein-containing complex binding#GO:0044877 regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of biosynthetic process#GO:0009889;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 chromatin/chromatin-binding, or -regulatory protein#PC00077 CIOIN|Ensembl=ENSCING00000001529.3|UniProtKB=F6Z3Y4 F6Z3Y4 LOC100182616 PTHR23308:SF28 NUCLEAR INHIBITOR OF PROTEIN PHOSPHATASE-1 NUCLEAR INHIBITOR OF PROTEIN PHOSPHATASE 1 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 RNA splicing factor#PC00148;RNA processing factor#PC00147 CIOIN|Ensembl=ENSCING00000012171.2|UniProtKB=F6TV26 F6TV26 LOC101243330 PTHR13822:SF7 ATP SYNTHASE DELTA/EPSILON CHAIN ATP SYNTHASE SUBUNIT DELTA, MITOCHONDRIAL monoatomic cation channel activity#GO:0005261;ligase activity#GO:0016874;inorganic molecular entity transmembrane transporter activity#GO:0015318;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;catalytic activity#GO:0003824;proton transmembrane transporter activity#GO:0015078;proton channel activity#GO:0015252;proton-transporting ATP synthase activity, rotational mechanism#GO:0046933;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;inorganic cation transmembrane transporter activity#GO:0022890;channel activity#GO:0015267;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 cellular aromatic compound metabolic process#GO:0006725;ribonucleoside triphosphate metabolic process#GO:0009199;nucleoside triphosphate metabolic process#GO:0009141;carbohydrate derivative metabolic process#GO:1901135;ATP biosynthetic process#GO:0006754;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ATP metabolic process#GO:0046034;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;purine nucleoside triphosphate biosynthetic process#GO:0009145;heterocycle metabolic process#GO:0046483;purine ribonucleoside triphosphate metabolic process#GO:0009205;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;ribonucleoside triphosphate biosynthetic process#GO:0009201;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;proton motive force-driven ATP synthesis#GO:0015986;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;nucleoside triphosphate biosynthetic process#GO:0009142;organophosphate metabolic process#GO:0019637;purine nucleoside triphosphate metabolic process#GO:0009144;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;ATPase complex#GO:1904949;organelle inner membrane#GO:0019866;mitochondrial proton-transporting ATP synthase complex#GO:0005753;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;proton-transporting two-sector ATPase complex#GO:0016469;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial envelope#GO:0005740;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227;proton-transporting ATP synthase complex#GO:0045259;mitochondrial protein-containing complex#GO:0098798 ATP synthase#PC00002;primary active transporter#PC00068;transporter#PC00227 CIOIN|Ensembl=ENSCING00000021590.1|UniProtKB=H2XK17 H2XK17 PTHR20953:SF3 KINASE-RELATED P-LOOP CONTAINING NUCLEOSIDE TRIPHOSPHATE HYDROLASES SUPERFAMILY PROTEIN CIOIN|Ensembl=ENSCING00000004358.3|UniProtKB=F7B4P8 F7B4P8 PTHR11109:SF7 GTP CYCLOHYDROLASE I GTP CYCLOHYDROLASE 1 carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;zinc ion binding#GO:0008270;binding#GO:0005488;catalytic activity#GO:0003824;transition metal ion binding#GO:0046914;metal ion binding#GO:0046872;cation binding#GO:0043169;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167 cellular aromatic compound metabolic process#GO:0006725;organic hydroxy compound metabolic process#GO:1901615;heterocycle metabolic process#GO:0046483;alcohol biosynthetic process#GO:0046165;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic hydroxy compound biosynthetic process#GO:1901617;alcohol metabolic process#GO:0006066;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;heterocycle biosynthetic process#GO:0018130;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;aromatic compound biosynthetic process#GO:0019438;small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 Tetrahydrofolate biosynthesis#P02742>GTP cyclohydrolase#P02951 CIOIN|Ensembl=ENSCING00000004084.3|UniProtKB=Q1RLH6 Q1RLH6 Ci-ZF(C2HC)-1 PTHR12247:SF131 POLYCOMB GROUP PROTEIN LD05287P protein binding#GO:0005515;protein-containing complex binding#GO:0044877;histone binding#GO:0042393;binding#GO:0005488;chromatin binding#GO:0003682 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of biosynthetic process#GO:0009890;negative regulation of RNA metabolic process#GO:0051253;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of metabolic process#GO:0009892;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 CIOIN|Ensembl=ENSCING00000020353.1|UniProtKB=H2XNX9 H2XNX9 PTHR24039:SF56 FIBRILLIN-RELATED FIBRILLIN-2-LIKE extracellular matrix structural protein#PC00103 CIOIN|Ensembl=ENSCING00000025218.1|UniProtKB=Q8HIN0 Q8HIN0 NADH4 PTHR43507:SF20 NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 4 NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 4 oxidoreductase activity, acting on NAD(P)H#GO:0016651;NADH dehydrogenase activity#GO:0003954;small molecule binding#GO:0036094;oxidoreductase activity#GO:0016491;binding#GO:0005488;catalytic activity#GO:0003824 aerobic respiration#GO:0009060;cellular respiration#GO:0045333;transmembrane transport#GO:0055085;proton transmembrane transport#GO:1902600;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;generation of precursor metabolites and energy#GO:0006091;cellular metabolic process#GO:0044237;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;energy derivation by oxidation of organic compounds#GO:0015980;localization#GO:0051179;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;metabolic process#GO:0008152 envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;respiratory chain complex#GO:0098803;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transporter complex#GO:1990351;oxidoreductase complex#GO:1990204;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;respirasome#GO:0070469;mitochondrial respiratory chain complex I#GO:0005747;protein-containing complex#GO:0032991;mitochondrial envelope#GO:0005740;mitochondrial respirasome#GO:0005746;transmembrane transporter complex#GO:1902495;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227;respiratory chain complex I#GO:0045271;NADH dehydrogenase complex#GO:0030964;mitochondrial protein-containing complex#GO:0098798 oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000013908.2|UniProtKB=H2XSS1 H2XSS1 PTHR18853:SF10 FORKHEAD-ASSOCIATED DOMAIN-CONTAINING PROTEIN 1-RELATED FHA DOMAIN-CONTAINING PROTEIN helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 CIOIN|Ensembl=ENSCING00000001372.3|UniProtKB=F6SAA4 F6SAA4 LOC100181702 PTHR11210:SF60 RING BOX RING-BOX PROTEIN 2 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;cullin family protein binding#GO:0097602;protein binding#GO:0005515;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cullin-RING ubiquitin ligase complex#GO:0031461;catalytic complex#GO:1902494;transferase complex#GO:1990234;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000018486.1|UniProtKB=H2Y1B1 H2Y1B1 PTHR15934:SF2 RNA 2',3'-CYCLIC PHOSPHODIESTERASE A-KINASE ANCHOR PROTEIN 7-LIKE PHOSPHOESTERASE DOMAIN-CONTAINING PROTEIN protein kinase A binding#GO:0051018;protein kinase A regulatory subunit binding#GO:0034237;protein binding#GO:0005515;binding#GO:0005488 regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;regulation of signaling#GO:0023051;biological regulation#GO:0065007;regulation of intracellular signal transduction#GO:1902531 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 RNA processing factor#PC00147;RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000019102.1|UniProtKB=H2XLR4 H2XLR4 PTHR12263:SF0 VACUOLAR ATP SYNTHASE SUBUNIT H V-TYPE PROTON ATPASE SUBUNIT localization#GO:0051179;establishment of localization#GO:0051234;cellular process#GO:0009987;transmembrane transport#GO:0055085;transport#GO:0006810 ATP synthase#PC00002;transporter#PC00227 CIOIN|Ensembl=ENSCING00000012257.2|UniProtKB=F7ALU8 F7ALU8 LOC100176140 PTHR24168:SF21 KN MOTIF AND ANKYRIN REPEAT DOMAIN-CONTAINING KANK, ISOFORM D regulation of anatomical structure size#GO:0090066;negative regulation of protein polymerization#GO:0032272;negative regulation of biological process#GO:0048519;regulation of actin filament length#GO:0030832;regulation of organelle organization#GO:0033043;regulation of actin filament organization#GO:0110053;regulation of cellular component organization#GO:0051128;cellular component organization#GO:0016043;regulation of actin polymerization or depolymerization#GO:0008064;cellular process#GO:0009987;regulation of actin filament polymerization#GO:0030833;regulation of cellular component size#GO:0032535;negative regulation of supramolecular fiber organization#GO:1902904;regulation of supramolecular fiber organization#GO:1902903;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of cytoskeleton organization#GO:0051493;regulation of protein-containing complex assembly#GO:0043254;regulation of biological quality#GO:0065008;regulation of cellular process#GO:0050794;regulation of cellular component biogenesis#GO:0044087;negative regulation of actin filament polymerization#GO:0030837;negative regulation of organelle organization#GO:0010639;biological regulation#GO:0065007;regulation of actin cytoskeleton organization#GO:0032956;negative regulation of protein-containing complex assembly#GO:0031333;regulation of actin filament-based process#GO:0032970;negative regulation of cellular component organization#GO:0051129;regulation of protein polymerization#GO:0032271;negative regulation of cytoskeleton organization#GO:0051494;negative regulation of cellular process#GO:0048523 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-motor actin binding protein#PC00165 CIOIN|Ensembl=ENSCING00000005046.3|UniProtKB=F6SMP7 F6SMP7 PTHR19444:SF13 UNC-93 RELATED PROTEIN UNC-93 HOMOLOG A membrane-bound signaling molecule#PC00152 CIOIN|Ensembl=ENSCING00000002399.3|UniProtKB=F6T3H3 F6T3H3 LOC100181607 PTHR46989:SF3 USP DOMAIN-CONTAINING PROTEIN USPA DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000003473.3|UniProtKB=F6TMY0 F6TMY0 PTHR20875:SF2 EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 6-RELATED EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 6 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 calmodulin-related#PC00061 CIOIN|Ensembl=ENSCING00000001954.3|UniProtKB=F6XTZ0 F6XTZ0 PTHR12566:SF9 CYTOPLASMIC POLYADENYLATION ELEMENT BINDING PROTEIN CPEB CYTOPLASMIC POLYADENYLATION ELEMENT-BINDING PROTEIN 1 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;translation regulator activity#GO:0045182;binding#GO:0005488;organic cyclic compound binding#GO:0097159;ribonucleoprotein complex binding#GO:0043021;ribosome binding#GO:0043022;mRNA binding#GO:0003729;protein-containing complex binding#GO:0044877;translation regulator activity, nucleic acid binding#GO:0090079;translation factor activity, RNA binding#GO:0008135;mRNA 3'-UTR binding#GO:0003730 negative regulation of gene expression#GO:0010629;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;negative regulation of biosynthetic process#GO:0009890;regulation of amide metabolic process#GO:0034248;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of translation#GO:0017148;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;post-transcriptional regulation of gene expression#GO:0010608;biological regulation#GO:0065007;regulation of translation#GO:0006417;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;synapse#GO:0045202;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;neuron projection#GO:0043005;cell junction#GO:0030054;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 mRNA polyadenylation factor#PC00146;RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000022296.1|UniProtKB=A0A1W3JHE2 A0A1W3JHE2 LOC100186557 PTHR36474:SF1 PROTEIN LIAT1 PROTEIN LIAT1 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 CIOIN|Ensembl=ENSCING00000000466.3|UniProtKB=F6YW52 F6YW52 LOC100179981 PTHR12002:SF116 CLAUDIN CLAUDIN-11-LIKE cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cell-cell junction organization#GO:0045216;cellular component biogenesis#GO:0044085;cell-cell junction assembly#GO:0007043;cell junction organization#GO:0034330;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;cell adhesion#GO:0007155;cellular process#GO:0009987 tight junction#GO:0070160;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cell junction#GO:0030054;bicellular tight junction#GO:0005923;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;apical junction complex#GO:0043296;plasma membrane#GO:0005886 cell junction protein#PC00070;tight junction#PC00214 CIOIN|Ensembl=ENSCING00000006222.3|UniProtKB=F6YW80 F6YW80 PTHR31859:SF9 TETRATRICOPEPTIDE REPEAT PROTEIN 39 FAMILY MEMBER TETRATRICOPEPTIDE REPEAT PROTEIN 39B CIOIN|Ensembl=ENSCING00000023672.1|UniProtKB=H2XQM6 H2XQM6 PTHR14336:SF15 TANDEM PH DOMAIN CONTAINING PROTEIN DUAL ADAPTER FOR PHOSPHOTYROSINE AND 3-PHOSPHOTYROSINE AND 3-PHOSPHOINOSITIDE CIOIN|Ensembl=ENSCING00000002232.3|UniProtKB=F6Z6H7 F6Z6H7 LOC100179894 PTHR13710:SF120 DNA HELICASE RECQ FAMILY MEMBER BIFUNCTIONAL 3'-5' EXONUCLEASE_ATP-DEPENDENT HELICASE WRN ATP-dependent activity, acting on DNA#GO:0008094;3'-5' DNA helicase activity#GO:0043138;helicase activity#GO:0004386;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;DNA helicase activity#GO:0003678;catalytic activity, acting on DNA#GO:0140097 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;double-strand break repair#GO:0006302;nucleobase-containing compound metabolic process#GO:0006139;DNA geometric change#GO:0032392;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;recombinational repair#GO:0000725;DNA duplex unwinding#GO:0032508;DNA-templated DNA replication#GO:0006261;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;DNA unwinding involved in DNA replication#GO:0006268;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;double-strand break repair via homologous recombination#GO:0000724;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;DNA conformation change#GO:0071103;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;organelle organization#GO:0006996;chromosome organization#GO:0051276;cellular response to stress#GO:0033554;DNA replication#GO:0006260;DNA metabolic process#GO:0006259 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA helicase#PC00011;DNA metabolism protein#PC00009 p53 pathway#P00059>WRN#P04617 CIOIN|Ensembl=ENSCING00000014217.2|UniProtKB=F6YKY6 F6YKY6 PTHR13826:SF14 INTESTINAL TREFOIL FACTOR-RELATED TREFOIL FACTOR 2 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 CIOIN|Ensembl=ENSCING00000018672.1|UniProtKB=H2XLE0 H2XLE0 PTHR45749:SF14 FAMILY NOT NAMED TTF-TYPE DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000022039.1|UniProtKB=H2XLH6 H2XLH6 PTHR24347:SF393 SERINE/THREONINE-PROTEIN KINASE SPAGHETTI-SQUASH ACTIVATOR, ISOFORM C transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>MLCK#P00877;Cytoskeletal regulation by Rho GTPase#P00016>MLCK#P00514 CIOIN|Ensembl=ENSCING00000010069.3|UniProtKB=F6QD44 F6QD44 PTHR21178:SF8 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 61 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 61 structural protein#PC00211 CIOIN|Ensembl=ENSCING00000009621.3|UniProtKB=F6ZV29 F6ZV29 PTHR24412:SF466 KELCH PROTEIN RING CANAL KELCH PROTEIN scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000011411.2|UniProtKB=F7AXH3 F7AXH3 PTHR34828:SF1 TESTIS-EXPRESSED PROTEIN 45 TESTIS-EXPRESSED PROTEIN 45 CIOIN|Ensembl=ENSCING00000003060.3|UniProtKB=F6PPN6 F6PPN6 LOC100186455 PTHR14002:SF20 ENDOGLIN/TGF-BETA RECEPTOR TYPE III ZONA PELLUCIDA-LIKE DOMAIN-CONTAINING PROTEIN 1 transmembrane signal receptor#PC00197 CIOIN|Ensembl=ENSCING00000022913.1|UniProtKB=H2XW85 H2XW85 PTHR11559:SF424 CARBOXYLESTERASE CARBOXYLESTERASE 1D-LIKE ISOFORM X1 esterase#PC00097;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000021136.1|UniProtKB=H2XU88 H2XU88 PTHR13950:SF9 RABCONNECTIN-RELATED RABCONNECTIN-3A regulation of intracellular pH#GO:0051453;regulation of pH#GO:0006885;regulation of biological quality#GO:0065008;intracellular monoatomic cation homeostasis#GO:0030003;biological regulation#GO:0065007;intracellular pH reduction#GO:0051452;monoatomic cation homeostasis#GO:0055080;homeostatic process#GO:0042592;intracellular monoatomic ion homeostasis#GO:0006873;chemical homeostasis#GO:0048878;vacuolar acidification#GO:0007035;cellular homeostasis#GO:0019725;regulation of cellular pH#GO:0030641;intracellular chemical homeostasis#GO:0055082;monoatomic ion homeostasis#GO:0050801 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000000338.3|UniProtKB=H2XKS6 H2XKS6 LOC100175738 PTHR10759:SF0 60S RIBOSOMAL PROTEIN L34 60S RIBOSOMAL PROTEIN L34 ribosomal protein#PC00202;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000004068.3|UniProtKB=F7B6D7 F7B6D7 PTHR15666:SF1 COMM DOMAIN CONTAINING PROTEIN 5 COMM DOMAIN-CONTAINING PROTEIN 5 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein-binding activity modulator#PC00095 CIOIN|Ensembl=ENSCING00000006922.3|UniProtKB=F6WAK8 F6WAK8 LOC100176883 PTHR15852:SF54 PLASTID TRANSCRIPTIONALLY ACTIVE PROTEIN PROTEIN SSUH2 HOMOLOG CIOIN|Ensembl=ENSCING00000008657.3|UniProtKB=F6ZY44 F6ZY44 LOC100185889 PTHR11476:SF7 HISTIDYL-TRNA SYNTHETASE HISTIDINE--TRNA LIGASE aminoacyl-tRNA synthetase#PC00047;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000009101.3|UniProtKB=F6Q9B5 F6Q9B5 LOC100178741 PTHR11547:SF57 ARGININE OR CREATINE KINASE PHOSPHAGEN KINASE C-TERMINAL DOMAIN-CONTAINING PROTEIN transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301 organophosphate biosynthetic process#GO:0090407;nitrogen compound metabolic process#GO:0006807;cellular modified amino acid metabolic process#GO:0006575;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;organophosphate metabolic process#GO:0019637;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;metabolic process#GO:0008152;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 amino acid kinase#PC00045 CIOIN|Ensembl=ENSCING00000008166.3|UniProtKB=F6UQ99 F6UQ99 PTHR45758:SF20 MITOFERRIN-1-RELATED MITOFERRIN-2 inorganic molecular entity transmembrane transporter activity#GO:0015318;transmembrane transporter activity#GO:0022857;monoatomic cation transmembrane transporter activity#GO:0008324;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;inorganic cation transmembrane transporter activity#GO:0022890;metal ion transmembrane transporter activity#GO:0046873 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;iron ion transmembrane transport#GO:0034755;mitochondrial transport#GO:0006839;localization#GO:0051179;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transport#GO:0006812;iron ion transport#GO:0006826;transition metal ion transport#GO:0000041;monoatomic ion transport#GO:0006811;mitochondrial transmembrane transport#GO:1990542;monoatomic cation transmembrane transport#GO:0098655 envelope#GO:0031975;cytoplasm#GO:0005737;mitochondrial membrane#GO:0031966;intracellular membrane-bounded organelle#GO:0043231;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000000498.3|UniProtKB=F6VQ85 F6VQ85 PTHR13986:SF8 PROTEIN LYSINE HYDROXYLATION COMPLEX COMPONENT PROLYL 3-HYDROXYLASE 1-LIKE PROTEIN collagen binding#GO:0005518;protein-containing complex binding#GO:0044877;binding#GO:0005488 cellular component organization or biogenesis#GO:0071840;extracellular structure organization#GO:0043062;external encapsulating structure organization#GO:0045229;supramolecular fiber organization#GO:0097435;collagen fibril organization#GO:0030199;cellular component organization#GO:0016043;cellular process#GO:0009987;extracellular matrix organization#GO:0030198 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000022654.1|UniProtKB=H2XRG7 H2XRG7 PTHR42760:SF83 SHORT-CHAIN DEHYDROGENASES/REDUCTASES FAMILY MEMBER (3R)-3-HYDROXYACYL-COA DEHYDROGENASE oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 organic acid biosynthetic process#GO:0016053;lipid metabolic process#GO:0006629;oxoacid metabolic process#GO:0043436;monocarboxylic acid biosynthetic process#GO:0072330;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;fatty acid metabolic process#GO:0006631;small molecule biosynthetic process#GO:0044283;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;fatty acid biosynthetic process#GO:0006633;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000018116.1|UniProtKB=H2XK93 H2XK93 LOC100178835 PTHR13100:SF10 CELL GROWTH-REGULATING NUCLEOLAR PROTEIN LYAR CELL GROWTH-REGULATING NUCLEOLAR PROTEIN nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;cellular component biogenesis#GO:0044085;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;negative regulation of RNA biosynthetic process#GO:1902679;regulation of transcription by RNA polymerase II#GO:0006357;RNA processing#GO:0006396;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;ribosome biogenesis#GO:0042254;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;regulation of DNA-templated transcription#GO:0006355;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;negative regulation of metabolic process#GO:0009892;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;rRNA metabolic process#GO:0016072;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;ribonucleoprotein complex biogenesis#GO:0022613;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA processing factor#PC00147 CIOIN|Ensembl=ENSCING00000020374.1|UniProtKB=H2XZI2 H2XZI2 PTHR23516:SF1 SAM (S-ADENOSYL METHIONINE) TRANSPORTER MOLYBDATE-ANION TRANSPORTER cellular anatomical entity#GO:0110165;membrane#GO:0016020 transporter#PC00227 CIOIN|Ensembl=ENSCING00000008954.3|UniProtKB=F6Q601 F6Q601 PTHR43134:SF1 SIGNAL RECOGNITION PARTICLE RECEPTOR SUBUNIT ALPHA SIGNAL RECOGNITION PARTICLE RECEPTOR SUBUNIT ALPHA GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;binding#GO:0005488;catalytic activity#GO:0003824;ribonucleoprotein complex binding#GO:0043021;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;protein-containing complex binding#GO:0044877;ribonucleoside triphosphate phosphatase activity#GO:0017111 localization#GO:0051179;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;protein targeting#GO:0006605;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104 cellular anatomical entity#GO:0110165;membrane#GO:0016020 G-protein#PC00020 CIOIN|Ensembl=ENSCING00000007286.3|UniProtKB=F6SUS9 F6SUS9 PTHR11835:SF34 DECARBOXYLATING DEHYDROGENASES-ISOCITRATE, ISOPROPYLMALATE, TARTRATE ISOCITRATE DEHYDROGENASE [NAD] SUBUNIT ALPHA, MITOCHONDRIAL oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 organic hydroxy compound metabolic process#GO:1901615;oxoacid metabolic process#GO:0043436;aerobic respiration#GO:0009060;cellular respiration#GO:0045333;generation of precursor metabolites and energy#GO:0006091;cellular metabolic process#GO:0044237;alcohol metabolic process#GO:0006066;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;energy derivation by oxidation of organic compounds#GO:0015980;tricarboxylic acid cycle#GO:0006099;primary metabolic process#GO:0044238;secondary alcohol metabolic process#GO:1902652;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 dehydrogenase#PC00092;oxidoreductase#PC00176 Leucine biosynthesis#P02749>3-Isopropylmalate dehydrogenase#P03001 CIOIN|Ensembl=ENSCING00000024952.1|UniProtKB=H2XRQ0 H2XRQ0 PTHR15427:SF50 EMILIN ELASTIN MICROFIBRIL INTERFACE-LOCATED PROTEIN ELASTIN MICROFIBRIL INTERFACER COMPLEMENT C1Q TUMOR NECROSIS FACTOR-RELATED PROTEIN 2-LIKE scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000019431.1|UniProtKB=H2XYR8 H2XYR8 PTHR11559:SF424 CARBOXYLESTERASE CARBOXYLESTERASE 1D-LIKE ISOFORM X1 esterase#PC00097;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000009009.2|UniProtKB=Q7YT70 Q7YT70 LOC445704 PTHR24072:SF192 RHO FAMILY GTPASE CDC42 HOMOLOG GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;enzyme binding#GO:0019899;ribonucleoside triphosphate phosphatase activity#GO:0017111;kinase binding#GO:0019900;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;heterocyclic compound binding#GO:1901363;protein kinase binding#GO:0019901;anion binding#GO:0043168;ion binding#GO:0043167 small GTPase#PC00208 TGF-beta signaling pathway#P00052>Ras-GDP#P01291;Huntington disease#P00029>Rac#P00775;Cytoskeletal regulation by Rho GTPase#P00016>Cdc42#P00515;Ras Pathway#P04393>Cdc42#P04569;p38 MAPK pathway#P05918>Cdc42#P06041;TGF-beta signaling pathway#P00052>Ras-GTP#P01280;Axon guidance mediated by netrin#P00009>cdc42#P00364;Integrin signalling pathway#P00034>Cdc42#P00938;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Cdc42#P00834;Axon guidance mediated by Slit/Robo#P00008>Cdc42#P00349;FGF signaling pathway#P00021>Rac#P00645 CIOIN|Ensembl=ENSCING00000009595.3|UniProtKB=F7AWZ4 F7AWZ4 PTHR46527:SF1 NUCLEOPORIN-LIKE PROTEIN 2 NUCLEOPORIN NUP42 transporter#PC00227 CIOIN|Ensembl=ENSCING00000001960.3|UniProtKB=Q4H301 Q4H301 Ci-p53_p73-a PTHR11447:SF16 CELLULAR TUMOR ANTIGEN P53 P53 PROTEIN LONG FORM VARIANT 1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 P53-like transcription factor#PC00253;immunoglobulin fold transcription factor#PC00251 Huntington disease#P00029>p53#P00797 CIOIN|Ensembl=ENSCING00000008981.3|UniProtKB=F6PKV2 F6PKV2 PTHR24068:SF144 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 C-RELATED ubiquitin-like protein conjugating enzyme activity#GO:0061650;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin conjugating enzyme activity#GO:0061631;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 regulation of chromosome segregation#GO:0051983;macromolecule modification#GO:0043412;protein catabolic process#GO:0030163;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;regulation of cellular component organization#GO:0051128;post-translational protein modification#GO:0043687;regulation of biological process#GO:0050789;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;protein polyubiquitination#GO:0000209;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of chromosome organization#GO:0033044;macromolecule catabolic process#GO:0009057;protein ubiquitination#GO:0016567;modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation or removal#GO:0070647;regulation of mitotic cell cycle phase transition#GO:1901990;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;regulation of organelle organization#GO:0033043;regulation of cell cycle phase transition#GO:1901987;organonitrogen compound metabolic process#GO:1901564;regulation of mitotic metaphase/anaphase transition#GO:0030071;regulation of cell cycle process#GO:0010564;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;anaphase-promoting complex-dependent catabolic process#GO:0031145;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;regulation of sister chromatid segregation#GO:0033045;regulation of mitotic cell cycle#GO:0007346 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 Ubiquitin proteasome pathway#P00060>E2#P01491 CIOIN|Ensembl=ENSCING00000003177.3|UniProtKB=F6QDX7 F6QDX7 LOC100178412 PTHR11440:SF97 LECITHIN-CHOLESTEROL ACYLTRANSFERASE-RELATED BCDNA.GH02384 acyltransferase#PC00042 CIOIN|Ensembl=ENSCING00000000849.2|UniProtKB=F6R0T4 F6R0T4 PTHR19143:SF459 FIBRINOGEN/TENASCIN/ANGIOPOEITIN FIBRINOGEN C-TERMINAL DOMAIN-CONTAINING PROTEIN external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 CIOIN|Ensembl=ENSCING00000024451.1|UniProtKB=H2XZI8 H2XZI8 PTHR10174:SF225 ALPHA-TOCOPHEROL TRANSFER PROTEIN-RELATED ALPHA-TOCOPHEROL TRANSFER PROTEIN phosphatidylinositol bisphosphate binding#GO:1902936;lipid binding#GO:0008289;phosphatidylinositol binding#GO:0035091;phospholipid binding#GO:0005543;phosphatidylinositol phosphate binding#GO:1901981;binding#GO:0005488 cellular anatomical entity#GO:0110165;membrane#GO:0016020 transfer/carrier protein#PC00219 CIOIN|Ensembl=ENSCING00000009745.3|UniProtKB=F6TIF0 F6TIF0 PTHR11388:SF160 ORGANIC ANION TRANSPORTER SOLUTE CARRIER ORGANIC ANION TRANSPORTER FAMILY MEMBER secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 localization#GO:0051179;organic substance transport#GO:0071702;establishment of localization#GO:0051234;organic anion transport#GO:0015711;transport#GO:0006810 basal plasma membrane#GO:0009925;basolateral plasma membrane#GO:0016323;plasma membrane region#GO:0098590;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;basal part of cell#GO:0045178;plasma membrane#GO:0005886 transporter#PC00227 CIOIN|Ensembl=ENSCING00000008248.3|UniProtKB=F6QZL4 F6QZL4 PTHR46091:SF3 BLR7054 PROTEIN AMINE OXIDASE DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000000910.3|UniProtKB=F6U144 F6U144 PTHR46182:SF2 FI19480P1 FI19480P1 cell differentiation#GO:0030154;cellular developmental process#GO:0048869;system development#GO:0048731;neurogenesis#GO:0022008;anatomical structure development#GO:0048856;neuron migration#GO:0001764;multicellular organism development#GO:0007275;developmental process#GO:0032502;multicellular organismal process#GO:0032501;cell motility#GO:0048870;generation of neurons#GO:0048699;cellular process#GO:0009987;nervous system development#GO:0007399;cell migration#GO:0016477 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000004899.3|UniProtKB=F7B997 F7B997 PTHR11566:SF67 DYNAMIN DYNAMIN-LIKE 120 KDA PROTEIN, MITOCHONDRIAL GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;microtubule binding#GO:0008017;ribonucleoside triphosphate phosphatase activity#GO:0017111 mitochondrial fusion#GO:0008053;organelle localization#GO:0051640;transport#GO:0006810;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;organelle organization#GO:0006996;organelle fission#GO:0048285;mitochondrion organization#GO:0007005;peroxisome organization#GO:0007031;import into cell#GO:0098657;mitochondrial fission#GO:0000266;organelle fusion#GO:0048284 envelope#GO:0031975;membrane-enclosed lumen#GO:0031974;supramolecular complex#GO:0099080;mitochondrial membrane#GO:0031966;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;organelle membrane#GO:0031090;supramolecular polymer#GO:0099081;mitochondrion#GO:0005739;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;mitochondrial envelope#GO:0005740;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;mitochondrial intermembrane space#GO:0005758;cytoskeleton#GO:0005856;microtubule#GO:0005874 membrane traffic protein#PC00150 CIOIN|Ensembl=ENSCING00000018801.1|UniProtKB=Q1RL67 Q1RL67 Ci-ZF(C2H2)-138 PTHR24393:SF163 ZINC FINGER PROTEIN GASTRULA ZINC FINGER PROTEIN XLCGF7.1-LIKE DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 CIOIN|Ensembl=ENSCING00000008787.3|UniProtKB=E7FIZ4 E7FIZ4 nAChR PTHR18945:SF924 NEUROTRANSMITTER GATED ION CHANNEL NEURONAL ACETYLCHOLINE RECEPTOR SUBUNIT BETA-4-LIKE ISOFORM X1 transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;signaling receptor activity#GO:0038023;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;neurotransmitter receptor activity#GO:0030594;ligand-gated monoatomic ion channel activity#GO:0015276;transporter activity#GO:0005215;channel activity#GO:0015267;transmembrane signaling receptor activity#GO:0004888;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;molecular transducer activity#GO:0060089;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;ligand-gated channel activity#GO:0022834 response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;transmembrane transport#GO:0055085;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;membrane depolarization#GO:0051899;transport#GO:0006810;regulation of membrane potential#GO:0042391;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to nitrogen compound#GO:1901699;localization#GO:0051179;regulation of biological process#GO:0050789;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;cellular response to oxygen-containing compound#GO:1901701;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;synaptic signaling#GO:0099536;monoatomic ion transport#GO:0006811;signaling#GO:0023052;cell-cell signaling#GO:0007267;acetylcholine receptor signaling pathway#GO:0095500 membrane protein complex#GO:0098796;synapse#GO:0045202;plasma membrane signaling receptor complex#GO:0098802;transporter complex#GO:1990351;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;receptor complex#GO:0043235;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;neuron projection#GO:0043005;transmembrane transporter complex#GO:1902495;cell projection#GO:0042995;plasma membrane#GO:0005886 ligand-gated ion channel#PC00141;ion channel#PC00133;transporter#PC00227 CIOIN|Ensembl=ENSCING00000007041.3|UniProtKB=F6ZVH3 F6ZVH3 PTHR10183:SF379 CALPAIN CALPAIN-5 cysteine protease#PC00081;protease#PC00190 Huntington disease#P00029>Calpain#P00788 CIOIN|Ensembl=ENSCING00000019447.1|UniProtKB=H2XZ79 H2XZ79 PTHR24372:SF77 GLYCOPROTEIN HORMONE RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 response to organic substance#GO:0010033;positive regulation of adenylate cyclase activity#GO:0045762;regulation of lyase activity#GO:0051339;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;cellular response to stimulus#GO:0051716;regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;cellular response to endogenous stimulus#GO:0071495;cellular response to chemical stimulus#GO:0070887;positive regulation of catalytic activity#GO:0043085;cellular response to organic substance#GO:0071310;regulation of cyclase activity#GO:0031279;positive regulation of molecular function#GO:0044093;cell communication#GO:0007154;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;positive regulation of cyclase activity#GO:0031281;hormone-mediated signaling pathway#GO:0009755;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to endogenous stimulus#GO:0009719;response to hormone#GO:0009725;cellular response to hormone stimulus#GO:0032870;response to chemical#GO:0042221;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of lyase activity#GO:0051349;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 CIOIN|Ensembl=ENSCING00000021243.1|UniProtKB=H2XXZ1 H2XXZ1 LOC100179085 PTHR12373:SF0 ENHANCER OF RUDIMENTARY ERH ENHANCER OF RUDIMENTARY HOMOLOG DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 CIOIN|Ensembl=ENSCING00000013429.2|UniProtKB=F6V362 F6V362 LOC100183372 PTHR11955:SF147 FATTY ACID BINDING PROTEIN FATTY ACID-BINDING PROTEIN, LIVER-LIKE fatty acid binding#GO:0005504;small molecule binding#GO:0036094;binding#GO:0005488;carboxylic acid binding#GO:0031406;lipid binding#GO:0008289;ion binding#GO:0043167;organic acid binding#GO:0043177;anion binding#GO:0043168 localization#GO:0051179;monocarboxylic acid transport#GO:0015718;organic substance transport#GO:0071702;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;organic anion transport#GO:0015711;fatty acid transport#GO:0015908;organic acid transport#GO:0015849;transport#GO:0006810;carboxylic acid transport#GO:0046942;lipid localization#GO:0010876;lipid transport#GO:0006869 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transfer/carrier protein#PC00219 CIOIN|Ensembl=ENSCING00000016392.2|UniProtKB=F6S536 F6S536 PTHR47456:SF6 PHD-TYPE DOMAIN-CONTAINING PROTEIN SI:DKEY-31C13.1 CIOIN|Ensembl=ENSCING00000014653.2|UniProtKB=H2XWF5 H2XWF5 PTHR45617:SF170 LEUCINE RICH REPEAT FAMILY PROTEIN MIP14966P scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000007772.3|UniProtKB=F6XT42 F6XT42 PTHR24058:SF28 DUAL SPECIFICITY PROTEIN KINASE SERINE_THREONINE-PROTEIN KINASE MINIBRAIN transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;peptidyl-amino acid modification#GO:0018193;cellular process#GO:0009987;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;peptidyl-threonine phosphorylation#GO:0018107;nitrogen compound metabolic process#GO:0006807;peptidyl-serine modification#GO:0018209;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000001879.3|UniProtKB=F6SJE3 F6SJE3 PTHR13025:SF6 EF-HAND DOMAIN-CONTAINING PROTEIN D EF-HAND DOMAIN-CONTAINING PROTEIN-RELATED cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488 calmodulin-related#PC00061 CIOIN|Ensembl=ENSCING00000018211.1|UniProtKB=H2XLU9 H2XLU9 LOC113474045 PTHR12040:SF0 ANTI-SILENCING PROTEIN 1 HISTONE CHAPERONE ASF1 protein binding#GO:0005515;binding#GO:0005488;histone binding#GO:0042393 cellular component organization or biogenesis#GO:0071840;chromatin organization#GO:0006325;protein-DNA complex organization#GO:0071824;cellular component organization#GO:0016043;cellular process#GO:0009987;protein-containing complex organization#GO:0043933 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-DNA complex#GO:0032993;chromosome#GO:0005694;chromatin#GO:0000785;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 CIOIN|Ensembl=ENSCING00000017275.2|UniProtKB=F7AIB9 F7AIB9 PTHR10826:SF1 COMPLEMENT COMPONENT 1 COMPLEMENT COMPONENT 1 Q SUBCOMPONENT-BINDING PROTEIN, MITOCHONDRIAL complement component#PC00078 CIOIN|Ensembl=ENSCING00000021737.1|UniProtKB=H2Y1I4 H2Y1I4 PTHR10971:SF2 MRNA EXPORT FACTOR AND BUB3 DYNEIN AXONEMAL ASSEMBLY FACTOR 10 protein binding#GO:0005515;ubiquitin-like protein binding#GO:0032182;binding#GO:0005488;ubiquitin binding#GO:0043130 RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000020692.1|UniProtKB=A0A1W5BDZ3 A0A1W5BDZ3 LOC100187414 PTHR48036:SF6 SPLICING FACTOR (PAD-1), PUTATIVE (AFU_ORTHOLOGUE AFUA_1G15810)-RELATED RNA BINDING MOTIF PROTEIN 39B ISOFORM X1-RELATED ribonucleoprotein complex binding#GO:0043021;protein-containing complex binding#GO:0044877;binding#GO:0005488 RNA splicing factor#PC00148;RNA processing factor#PC00147 CIOIN|Ensembl=ENSCING00000008709.3|UniProtKB=F6WCD3 F6WCD3 PTHR24185:SF1 CALCIUM-INDEPENDENT PHOSPHOLIPASE A2-GAMMA CALCIUM-INDEPENDENT PHOSPHOLIPASE A2-GAMMA hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;phospholipase activity#GO:0004620;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;oxoacid metabolic process#GO:0043436;fatty acid metabolic process#GO:0006631;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular lipid metabolic process#GO:0044255;organic acid metabolic process#GO:0006082;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;membrane#GO:0016020 phospholipase#PC00186;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000020773.1|UniProtKB=H2XPH1 H2XPH1 PTHR15904:SF17 FAM13 RHO-GAP DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000000425.3|UniProtKB=F7AYX3 F7AYX3 PTHR31434:SF2 S PHASE CYCLIN A-ASSOCIATED PROTEIN IN THE ENDOPLASMIC RETICULUM S PHASE CYCLIN A-ASSOCIATED PROTEIN IN THE ENDOPLASMIC RETICULUM CIOIN|Ensembl=ENSCING00000021705.1|UniProtKB=H2XLC1 H2XLC1 PTHR28570:SF3 ASPARTYL AMINOPEPTIDASE ASPARTYL AMINOPEPTIDASE metalloprotease#PC00153;protease#PC00190 CIOIN|Ensembl=ENSCING00000013048.2|UniProtKB=F6T5H3 F6T5H3 PTHR24208:SF166 LIM/HOMEOBOX PROTEIN LHX LIM HOMEOBOX TRANSCRIPTION FACTOR 1 ALPHA, ISOFORM B sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 homeodomain transcription factor#PC00119 CIOIN|Ensembl=ENSCING00000000685.3|UniProtKB=F6QRG3 F6QRG3 LOC100176030 PTHR12848:SF16 REGULATORY-ASSOCIATED PROTEIN OF MTOR REGULATORY-ASSOCIATED PROTEIN OF MTOR molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 signal transduction#GO:0007165;regulation of catabolic process#GO:0009894;regulation of cellular component organization#GO:0051128;regulation of growth#GO:0040008;response to extracellular stimulus#GO:0009991;cellular response to nitrogen compound#GO:1901699;regulation of biological process#GO:0050789;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;cellular response to starvation#GO:0009267;intracellular signal transduction#GO:0035556;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of cell growth#GO:0001558;TOR signaling#GO:0031929;cellular response to extracellular stimulus#GO:0031668;positive regulation of growth#GO:0045927;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;cellular response to endogenous stimulus#GO:0071495;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;regulation of autophagy#GO:0010506;response to organonitrogen compound#GO:0010243;cell communication#GO:0007154;response to nutrient levels#GO:0031667;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;response to nitrogen compound#GO:1901698;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;cellular response to nutrient levels#GO:0031669;regulation of cellular process#GO:0050794;cellular response to organonitrogen compound#GO:0071417;response to starvation#GO:0042594;biological regulation#GO:0065007;cellular response to external stimulus#GO:0071496;cellular response to stress#GO:0033554;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;intracellular protein-containing complex#GO:0140535;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000009290.3|UniProtKB=F7B9W5 F7B9W5 LOC100186570 PTHR44390:SF1 CENTROSOMAL PROTEIN OF 41 KDA CENTROSOMAL PROTEIN OF 41 KDA organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cell projection organization#GO:0030030;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;microtubule cytoskeleton#GO:0015630;ciliary basal body#GO:0036064;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cilium#GO:0005929;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000024702.1|UniProtKB=H2XKH7 H2XKH7 PTHR24251:SF30 OVOCHYMASE-RELATED MEMBRANE FRIZZLED-RELATED PROTEIN serine protease#PC00203;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000015376.2|UniProtKB=F6YI87 F6YI87 LOC100181220 PTHR42961:SF2 IRON-SULFUR PROTEIN NUBPL IRON-SULFUR PROTEIN NUBPL small molecule binding#GO:0036094;binding#GO:0005488;iron-sulfur cluster binding#GO:0051536 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;iron-sulfur cluster assembly#GO:0016226;cellular component organization#GO:0016043;cellular process#GO:0009987 CIOIN|Ensembl=ENSCING00000010617.3|UniProtKB=F7BMM1 F7BMM1 LOC100179613 PTHR36978:SF4 P-LOOP CONTAINING NUCLEOTIDE TRIPHOSPHATE HYDROLASE P-LOOP CONTAINING NUCLEOSIDE TRIPHOSPHATE HYDROLASE PROTEIN metabolite interconversion enzyme#PC00262;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000014590.2|UniProtKB=F6SYM5 F6SYM5 PTHR23235:SF150 KRUEPPEL-LIKE TRANSCRIPTION FACTOR KRUEPPEL-LIKE FACTOR LUNA sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 CIOIN|Ensembl=ENSCING00000015164.2|UniProtKB=F6XYN0 F6XYN0 LOC100176296 PTHR24412:SF172 KELCH PROTEIN KELCH-LIKE PROTEIN 10 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000011670.2|UniProtKB=F6X8U3 F6X8U3 PTHR16039:SF1 HAUS AUGMIN-LIKE COMPLEX SUBUNIT 2 HAUS AUGMIN-LIKE COMPLEX SUBUNIT 2 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;cellular process#GO:0009987;microtubule polymerization or depolymerization#GO:0031109;chromosome segregation#GO:0007059;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule polymerization#GO:0046785;microtubule-based process#GO:0007017;protein-containing complex organization#GO:0043933;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;protein polymerization#GO:0051258;spindle assembly#GO:0051225;cell cycle#GO:0007049;cytoskeleton organization#GO:0007010;spindle organization#GO:0007051;non-membrane-bounded organelle assembly#GO:0140694;microtubule nucleation#GO:0007020 supramolecular complex#GO:0099080;spindle microtubule#GO:0005876;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;mitotic spindle#GO:0072686;microtubule cytoskeleton#GO:0015630;cytoskeleton#GO:0005856;microtubule#GO:0005874;spindle#GO:0005819 CIOIN|Ensembl=ENSCING00000011357.2|UniProtKB=F6U973 F6U973 PTHR43975:SF2 ZGC:101858 EG:BACR7A4.14 PROTEIN-RELATED CIOIN|Ensembl=ENSCING00000007491.3|UniProtKB=F6X7W0 F6X7W0 LOC100186950 PTHR11835:SF60 DECARBOXYLATING DEHYDROGENASES-ISOCITRATE, ISOPROPYLMALATE, TARTRATE ISOCITRATE DEHYDROGENASE [NAD] SUBUNIT, MITOCHONDRIAL oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 organic hydroxy compound metabolic process#GO:1901615;oxoacid metabolic process#GO:0043436;aerobic respiration#GO:0009060;cellular respiration#GO:0045333;generation of precursor metabolites and energy#GO:0006091;cellular metabolic process#GO:0044237;alcohol metabolic process#GO:0006066;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;energy derivation by oxidation of organic compounds#GO:0015980;tricarboxylic acid cycle#GO:0006099;primary metabolic process#GO:0044238;secondary alcohol metabolic process#GO:1902652;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 dehydrogenase#PC00092;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000006716.3|UniProtKB=Q1RL25 Q1RL25 Ci-ZF(UBP)-3 PTHR21646:SF5 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE-RELATED cysteine protease#PC00081;protease#PC00190 CIOIN|Ensembl=ENSCING00000012733.2|UniProtKB=F7A9P4 F7A9P4 PTHR20959:SF1 TRANSPORT AND GOLGI ORGANIZATION PROTEIN 6 FAMILY MEMBER TRANSPORT AND GOLGI ORGANIZATION PROTEIN 6 HOMOLOG cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;nitrogen compound transport#GO:0071705;protein secretion#GO:0009306;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;establishment of protein localization to extracellular region#GO:0035592;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;secretion#GO:0046903;protein transport#GO:0015031;protein localization to extracellular region#GO:0071692;export from cell#GO:0140352;secretion by cell#GO:0032940 CIOIN|Ensembl=ENSCING00000001445.3|UniProtKB=F6W768 F6W768 PTHR10454:SF232 CASPASE AT03047P-RELATED cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197;hydrolase activity#GO:0016787;cysteine-type endopeptidase activity involved in apoptotic process#GO:0097153;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 regulation of biological process#GO:0050789;positive regulation of apoptotic process#GO:0043065;positive regulation of programmed cell death#GO:0043068;regulation of apoptotic process#GO:0042981;regulation of cellular process#GO:0050794;apoptotic process#GO:0006915;biological regulation#GO:0065007;cell death#GO:0008219;programmed cell death#GO:0012501;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;regulation of programmed cell death#GO:0043067;positive regulation of cellular process#GO:0048522 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 protease#PC00190;protein modifying enzyme#PC00260 FAS signaling pathway#P00020>Caspase6#P00596;FAS signaling pathway#P00020>Pro-Caspase6#P00607 CIOIN|Ensembl=ENSCING00000005585.3|UniProtKB=F7BBW9 F7BBW9 LOC100185471 PTHR43742:SF9 TRIMETHYLAMINE-N-OXIDE REDUCTASE TETRATHIONATE REDUCTASE SUBUNIT A reductase#PC00198;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000020664.1|UniProtKB=Q1RL43 Q1RL43 Ci-ZF(C2H2)-170 PTHR23235:SF142 KRUEPPEL-LIKE TRANSCRIPTION FACTOR ZINC FINGER PROTEIN 384 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 CIOIN|Ensembl=ENSCING00000007909.3|UniProtKB=F7AAC1 F7AAC1 PTHR15327:SF0 MICROFIBRIL-ASSOCIATED PROTEIN MICROFIBRILLAR-ASSOCIATED PROTEIN 1 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;U2-type spliceosomal complex#GO:0005684;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 extracellular matrix protein#PC00102 CIOIN|Ensembl=ENSCING00000020368.1|UniProtKB=H2XS38 H2XS38 LOC100176688 PTHR22826:SF211 RHO GUANINE EXCHANGE FACTOR-RELATED LD43457P nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;guanyl-nucleotide exchange factor activity#GO:0005085 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 CIOIN|Ensembl=ENSCING00000001417.3|UniProtKB=F6YSA0 F6YSA0 PTHR23064:SF83 TROPONIN EF-HAND DOMAIN-CONTAINING PROTEIN multicellular organismal process#GO:0032501;nervous system process#GO:0050877;skeletal muscle contraction#GO:0003009;striated muscle contraction#GO:0006941;muscle system process#GO:0003012;muscle contraction#GO:0006936;system process#GO:0003008 supramolecular complex#GO:0099080;cellular anatomical entity#GO:0110165;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;contractile fiber#GO:0043292;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;sarcomere#GO:0030017;cytoskeleton#GO:0005856;myofibril#GO:0030016 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 CIOIN|Ensembl=ENSCING00000004225.3|UniProtKB=F6YGL5 F6YGL5 LOC100187059 PTHR10984:SF25 ENDOPLASMIC RETICULUM-GOLGI INTERMEDIATE COMPARTMENT PROTEIN ENDOPLASMIC RETICULUM-GOLGI INTERMEDIATE COMPARTMENT PROTEIN 3 cytoplasm#GO:0005737;COPII-coated ER to Golgi transport vesicle#GO:0030134;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cellular anatomical entity#GO:0110165;coated vesicle#GO:0030135;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000001951.3|UniProtKB=F6U9P7 F6U9P7 PTHR13615:SF3 GLYCOSYLTRANSFERASE-LIKE 1 GLYCOSYLTRANSFERASE-LIKE DOMAIN-CONTAINING PROTEIN 1 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000007386.3|UniProtKB=F6UKS5 F6UKS5 PTHR45653:SF10 DEDICATOR OF CYTOKINESIS MYOBLAST CITY, ISOFORM B nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;binding#GO:0005488;molecular function regulator activity#GO:0098772;enzyme binding#GO:0019899;protein binding#GO:0005515;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;guanyl-nucleotide exchange factor activity#GO:0005085 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 Integrin signalling pathway#P00034>Dock180#P00930 CIOIN|Ensembl=ENSCING00000005847.3|UniProtKB=F6VW40 F6VW40 PTHR16453:SF9 WD40 DOMAIN-CONTAINING PROTEIN MIO FAMILY MEMBER GATOR COMPLEX PROTEIN MIOS cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000007544.3|UniProtKB=F6T8P3 F6T8P3 PTHR43382:SF2 PROLYL-TRNA SYNTHETASE BIFUNCTIONAL GLUTAMATE_PROLINE--TRNA LIGASE catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;ligase activity#GO:0016874;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;peptide biosynthetic process#GO:0043043;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;intracellular protein-containing complex#GO:0140535;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622 aminoacyl-tRNA synthetase#PC00047;translational protein#PC00263 Heme biosynthesis#P02746>Glutamyl-tRNA-synthetase#P02977 CIOIN|Ensembl=ENSCING00000019033.1|UniProtKB=H2XWZ6 H2XWZ6 LOC100183691 PTHR13180:SF0 SMALL MEMBRANE PROTEIN-RELATED TRANSMEMBRANE PROTEIN 50A endosomal transport#GO:0016197;establishment of protein localization to vacuole#GO:0072666;cellular localization#GO:0051641;macromolecule localization#GO:0033036;protein targeting to vacuole#GO:0006623;vacuolar transport#GO:0007034;transport#GO:0006810;protein localization to vacuole#GO:0072665;late endosome to vacuole transport via multivesicular body sorting pathway#GO:0032511;protein targeting#GO:0006605;nitrogen compound transport#GO:0071705;late endosome to vacuole transport#GO:0045324;establishment of protein localization to organelle#GO:0072594;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;multivesicular body sorting pathway#GO:0071985;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;endosome transport via multivesicular body sorting pathway#GO:0032509;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;protein localization to organelle#GO:0033365;intracellular transport#GO:0046907 CIOIN|Ensembl=ENSCING00000005556.3|UniProtKB=F6VGI1 F6VGI1 PTHR12277:SF194 ALPHA/BETA HYDROLASE DOMAIN-CONTAINING PROTEIN FI04476P hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;phospholipase activity#GO:0004620;catalytic activity#GO:0003824;lysophospholipase activity#GO:0004622 lipid metabolic process#GO:0006629;neutral lipid catabolic process#GO:0046461;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;glycerophospholipid metabolic process#GO:0006650;glycerolipid catabolic process#GO:0046503;lipid catabolic process#GO:0016042;glycerophospholipid catabolic process#GO:0046475;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;acylglycerol metabolic process#GO:0006639;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate catabolic process#GO:0046434;acylglycerol catabolic process#GO:0046464;phosphate-containing compound metabolic process#GO:0006796;neutral lipid metabolic process#GO:0006638;glycerolipid metabolic process#GO:0046486;nitrogen compound metabolic process#GO:0006807;cellular modified amino acid metabolic process#GO:0006575;phospholipid catabolic process#GO:0009395;catabolic process#GO:0009056;organophosphate metabolic process#GO:0019637;organic substance catabolic process#GO:1901575;cellular lipid metabolic process#GO:0044255;cellular lipid catabolic process#GO:0044242;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 serine protease#PC00203;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000002571.3|UniProtKB=F6UEZ5 F6UEZ5 chat PTHR22589:SF14 CARNITINE O-ACYLTRANSFERASE CHOLINE O-ACETYLTRANSFERASE transferase activity#GO:0016740;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acetyltransferase activity#GO:0016407;catalytic activity#GO:0003824;O-acyltransferase activity#GO:0008374 trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;regulation of biological process#GO:0050789;anterograde trans-synaptic signaling#GO:0098916;chemical synaptic transmission#GO:0007268;nitrogen compound metabolic process#GO:0006807;synaptic signaling#GO:0099536;biological regulation#GO:0065007;neuromuscular synaptic transmission#GO:0007274;signaling#GO:0023052;cell-cell signaling#GO:0007267;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;neuron projection#GO:0043005;intracellular anatomical structure#GO:0005622 transferase#PC00220;acyltransferase#PC00042;metabolite interconversion enzyme#PC00262 Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>CAT#P01076;Nicotinic acetylcholine receptor signaling pathway#P00044>CAT#P01087;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>CAT#P01063 CIOIN|Ensembl=ENSCING00000002796.3|UniProtKB=F6XMP8 F6XMP8 PTHR24012:SF491 RNA BINDING PROTEIN LD36772P-RELATED nucleic acid binding#GO:0003676;single-stranded RNA binding#GO:0003727;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159;mRNA binding#GO:0003729;poly(A) binding#GO:0008143;mRNA 3'-UTR binding#GO:0003730 cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000000956.3|UniProtKB=K9J6P3 K9J6P3 PTHR24276:SF91 POLYSERASE-RELATED AT26814P-RELATED hydrolase activity#GO:0016787;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171 serine protease#PC00203;protease#PC00190 CIOIN|Ensembl=ENSCING00000019614.1|UniProtKB=H2Y1V5 H2Y1V5 LOC100178190 PTHR46002:SF5 EG:114D9.1 PROTEIN-RELATED EF-HAND DOMAIN-CONTAINING PROTEIN-RELATED regulation of sodium ion transmembrane transporter activity#GO:2000649;regulation of monoatomic ion transmembrane transport#GO:0034765;regulation of transmembrane transport#GO:0034762;regulation of sodium ion transport#GO:0002028;regulation of metal ion transport#GO:0010959;positive regulation of molecular function#GO:0044093;regulation of localization#GO:0032879;positive regulation of transport#GO:0051050;regulation of monoatomic cation transmembrane transport#GO:1904062;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;positive regulation of transporter activity#GO:0032411;regulation of transport#GO:0051049;regulation of cellular process#GO:0050794;regulation of molecular function#GO:0065009;biological regulation#GO:0065007;regulation of monoatomic ion transmembrane transporter activity#GO:0032412;regulation of transmembrane transporter activity#GO:0022898;regulation of monoatomic ion transport#GO:0043269;regulation of transporter activity#GO:0032409;positive regulation of biological process#GO:0048518 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 CIOIN|Ensembl=ENSCING00000024912.1|UniProtKB=H2XV16 H2XV16 PTHR12081:SF18 TRANSCRIPTION FACTOR E2F TRANSCRIPTION FACTOR E2F2-RELATED sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 p53 pathway feedback loops 2#P04398>E2F-1#P04652;p53 pathway#P00059>E2F-1#P04627;Cell cycle#P00013>E2F#P00488 CIOIN|Ensembl=ENSCING00000003650.3|UniProtKB=F7AY10 F7AY10 LOC100178300 PTHR31129:SF2 GLYCOPROTEIN HORMONE ALPHA-2 GLYCOPROTEIN HORMONE ALPHA-2 protein binding#GO:0005515;binding#GO:0005488;hormone receptor binding#GO:0051427;signaling receptor binding#GO:0005102 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 peptide hormone#PC00179 CIOIN|Ensembl=ENSCING00000002863.3|UniProtKB=F6TMW1 F6TMW1 PTHR23339:SF26 TYROSINE SPECIFIC PROTEIN PHOSPHATASE AND DUAL SPECIFICITY PROTEIN PHOSPHATASE DUAL SPECIFICITY PROTEIN PHOSPHATASE 23 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;protein tyrosine phosphatase activity#GO:0004725;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cell projection organization#GO:0030030;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 protein phosphatase#PC00195;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000000585.3|UniProtKB=F6PXS4 F6PXS4 LOC100184407 PTHR12318:SF0 TESTOSTERONE-REGULATED PROTEIN RP2 ACYL-COENZYME A DIPHOSPHATASE NUDT19 CIOIN|Ensembl=ENSCING00000024040.1|UniProtKB=H2Y371 H2Y371 PTHR23164:SF30 EARLY ENDOSOME ANTIGEN 1 EARLY ENDOSOME ANTIGEN 1 membrane trafficking regulatory protein#PC00151 CIOIN|Ensembl=ENSCING00000009105.3|UniProtKB=F6Q982 F6Q982 PTHR31331:SF1 LCCL DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_5G08630) CYSTEINE RICH SECRETORY PROTEIN LCCL DOMAIN CONTAINING 2 CIOIN|Ensembl=ENSCING00000024877.1|UniProtKB=H2XL05 H2XL05 LOC100182395 PTHR15588:SF9 LSM1 U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM8 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;mRNA splicing, via spliceosome#GO:0000398;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 U6 snRNP#GO:0005688;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;U4/U6 x U5 tri-snRNP complex#GO:0046540;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;spliceosomal snRNP complex#GO:0097525;small nuclear ribonucleoprotein complex#GO:0030532;protein-containing complex#GO:0032991;spliceosomal tri-snRNP complex#GO:0097526;membrane-bounded organelle#GO:0043227;precatalytic spliceosome#GO:0071011;Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513 RNA splicing factor#PC00148;RNA processing factor#PC00147 CIOIN|Ensembl=ENSCING00000008253.3|UniProtKB=F6QZH0 F6QZH0 PTHR24356:SF163 SERINE/THREONINE-PROTEIN KINASE 3-PHOSPHOINOSITIDE-DEPENDENT PROTEIN KINASE 1-RELATED transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular process#GO:0009987;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PDK1#P00831;Ras Pathway#P04393>PDK#P04555;CCKR signaling map#P06959>PDPK1#P07162;PI3 kinase pathway#P00048>PDK1 ACT#P01190;PI3 kinase pathway#P00048>PDK1#P01196;p53 pathway feedback loops 2#P04398>PDK1/2#P04656;p53 pathway#P00059>PDK1/2#P04616;Interleukin signaling pathway#P00036>PDK1/2#P00985;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>PDK1/2#P00903;PDGF signaling pathway#P00047>PDK1/2#P01164;PI3 kinase pathway#P00048>P110ACT#P01177 CIOIN|Ensembl=ENSCING00000020212.1|UniProtKB=H2XR12 H2XR12 PTHR22958:SF1 GLYCEROPHOSPHORYL DIESTER PHOSPHODIESTERASE GLYCEROPHOSPHOCHOLINE PHOSPHODIESTERASE GPCPD1 lipid metabolic process#GO:0006629;cellular metabolic process#GO:0044237;glycerophospholipid metabolic process#GO:0006650;glycerolipid catabolic process#GO:0046503;glycerophospholipid catabolic process#GO:0046475;lipid catabolic process#GO:0016042;cellular process#GO:0009987;phospholipid metabolic process#GO:0006644;phosphorus metabolic process#GO:0006793;organophosphate catabolic process#GO:0046434;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;phospholipid catabolic process#GO:0009395;catabolic process#GO:0009056;organophosphate metabolic process#GO:0019637;organic substance catabolic process#GO:1901575;cellular lipid metabolic process#GO:0044255;cellular lipid catabolic process#GO:0044242;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 phosphodiesterase#PC00185;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000001011.3|UniProtKB=F6Y0I3 F6Y0I3 LOC100175722 PTHR21113:SF4 AGAP001705-PA CHITIN-BINDING TYPE-4 DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000001771.3|UniProtKB=F6PX70 F6PX70 LOC100182499 PTHR23213:SF368 FORMIN-RELATED HISTONE H3-K79 METHYLTRANSFERASE CIOIN|Ensembl=ENSCING00000007814.3|UniProtKB=F6WH82 F6WH82 LOC100183539 PTHR43247:SF1 PHOSPHOSERINE AMINOTRANSFERASE PHOSPHOSERINE AMINOTRANSFERASE transferase activity#GO:0016740;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;transaminase activity#GO:0008483;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167 organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;proteinogenic amino acid metabolic process#GO:0170039;proteinogenic amino acid biosynthetic process#GO:0170038;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;alpha-amino acid biosynthetic process#GO:1901607;nitrogen compound metabolic process#GO:0006807;amino acid biosynthetic process#GO:0008652;alpha-amino acid metabolic process#GO:1901605;small molecule biosynthetic process#GO:0044283;L-amino acid biosynthetic process#GO:0170034;carboxylic acid metabolic process#GO:0019752;L-amino acid metabolic process#GO:0170033;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 transaminase#PC00216 Pyridoxal-5-phosphate biosynthesis#P02759>Phosphohydroxythreonine aminotransferase#P03058;Vitamin B6 metabolism#P02787>Phosphoserine transaminase#P03227;Serine glycine biosynthesis#P02776>Phosphoserine aminotransferase#P03157 CIOIN|Ensembl=ENSCING00000024773.1|UniProtKB=H2XJZ7 H2XJZ7 LOC100182401 PTHR13664:SF0 BECLIN 1-ASSOCIATED AUTOPHAGY-RELATED KEY REGULATOR BECLIN 1-ASSOCIATED AUTOPHAGY-RELATED KEY REGULATOR protein-membrane adaptor activity#GO:0043495;molecular adaptor activity#GO:0060090;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;enzyme regulator activity#GO:0030234;protein-macromolecule adaptor activity#GO:0030674 cellular component biogenesis#GO:0044085;organelle localization#GO:0051640;macroautophagy#GO:0016236;mitophagy#GO:0000423;autophagy of mitochondrion#GO:0000422;response to extracellular stimulus#GO:0009991;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;cellular component disassembly#GO:0022411;cellular response to starvation#GO:0009267;catabolic process#GO:0009056;mitochondrion organization#GO:0007005;autophagosome maturation#GO:0097352;cellular response to extracellular stimulus#GO:0031668;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;cellular component assembly#GO:0022607;cellular response to stimulus#GO:0051716;protein-containing complex disassembly#GO:0032984;cellular metabolic process#GO:0044237;cell communication#GO:0007154;cellular component organization#GO:0016043;response to nutrient levels#GO:0031667;cellular process#GO:0009987;organelle disassembly#GO:1903008;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;response to stress#GO:0006950;organelle organization#GO:0006996;cellular response to nutrient levels#GO:0031669;protein-containing complex organization#GO:0043933;response to starvation#GO:0042594;cellular response to external stimulus#GO:0071496;autophagosome assembly#GO:0000045;cellular response to stress#GO:0033554;autophagy#GO:0006914 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;phosphatidylinositol 3-kinase complex#GO:0005942;transferase complex#GO:1990234;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;phosphatidylinositol 3-kinase complex, class III#GO:0035032;intracellular organelle#GO:0043229;autophagosome#GO:0005776;transferase complex, transferring phosphorus-containing groups#GO:0061695;extrinsic component of membrane#GO:0019898;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;phagophore assembly site#GO:0000407;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227 CIOIN|Ensembl=ENSCING00000009267.3|UniProtKB=F6S1K1 F6S1K1 LOC100181858 PTHR12743:SF0 CYTOCHROME C1 HEME LYASE HOLOCYTOCHROME C-TYPE SYNTHASE lyase activity#GO:0016829;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein-containing complex assembly#GO:0065003;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular component organization#GO:0016043;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nitrogen compound metabolic process#GO:0006807;protein-containing complex organization#GO:0043933;cytochrome complex assembly#GO:0017004;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 lyase#PC00144 CIOIN|Ensembl=ENSCING00000005180.3|UniProtKB=F6RXY6 F6RXY6 LOC100176802 PTHR10574:SF406 NETRIN/LAMININ-RELATED LAMININ SUBUNIT ALPHA 5 animal organ morphogenesis#GO:0009887;anatomical structure morphogenesis#GO:0009653;tissue development#GO:0009888;anatomical structure development#GO:0048856;animal organ development#GO:0048513;developmental process#GO:0032502 extracellular matrix protein#PC00102 Integrin signalling pathway#P00034>Laminin#P00947 CIOIN|Ensembl=ENSCING00000005544.3|UniProtKB=F6XER0 F6XER0 LOC100186910 PTHR11060:SF0 PROTEIN MEMO1 PROTEIN MEMO1 CIOIN|Ensembl=ENSCING00000011331.2|UniProtKB=F6UXZ8 F6UXZ8 PTHR23349:SF57 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, TWIST FACTOR IN THE GERMLINE ALPHA sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 basic helix-loop-helix transcription factor#PC00055 CIOIN|Ensembl=ENSCING00000003797.3|UniProtKB=F7ACJ3 F7ACJ3 LOC100180398 PTHR22957:SF498 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN RAB-GAP TBC DOMAIN-CONTAINING PROTEIN nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 regulation of molecular function#GO:0065009;regulation of GTPase activity#GO:0043087;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;activation of GTPase activity#GO:0090630;biological regulation#GO:0065007;positive regulation of molecular function#GO:0044093;regulation of hydrolase activity#GO:0051336;regulation of catalytic activity#GO:0050790;positive regulation of hydrolase activity#GO:0051345 GTPase-activating protein#PC00257 CIOIN|Ensembl=ENSCING00000008558.3|UniProtKB=F6XP34 F6XP34 LOC100178746 PTHR45871:SF1 N-ACETYLGLUCOSAMINYL-PHOSPHATIDYLINOSITOL BIOSYNTHETIC PROTEIN PHOSPHATIDYLINOSITOL N-ACETYLGLUCOSAMINYLTRANSFERASE SUBUNIT A CIOIN|Ensembl=ENSCING00000022311.1|UniProtKB=H2XPJ1 H2XPJ1 PTHR10209:SF881 OXIDOREDUCTASE, 2OG-FE II OXYGENASE FAMILY PROTEIN FI07970P-RELATED oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000015968.2|UniProtKB=F6X3H1 F6X3H1 LOC778836 PTHR24339:SF67 HOMEOBOX PROTEIN EMX-RELATED GNOT1 HOMEODOMAIN PROTEIN-RELATED sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;neurogenesis#GO:0022008;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;multicellular organism development#GO:0007275;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;system development#GO:0048731;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;neuron differentiation#GO:0030182;multicellular organismal process#GO:0032501;central nervous system development#GO:0007417;regulation of macromolecule biosynthetic process#GO:0010556;generation of neurons#GO:0048699;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 CIOIN|Ensembl=ENSCING00000007855.3|UniProtKB=F6W5S5 F6W5S5 PTHR11662:SF399 SOLUTE CARRIER FAMILY 17 FI19708P1-RELATED secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000002634.3|UniProtKB=F6ZJF3 F6ZJF3 PTHR33664:SF1 RCG26366 DYNEIN AXONEMAL ASSEMBLY FACTOR 9 CIOIN|Ensembl=ENSCING00000001500.3|UniProtKB=F6SW03 F6SW03 PTHR23333:SF20 UBX DOMAIN CONTAINING PROTEIN NSFL1 COFACTOR P47 protein binding#GO:0005515;ubiquitin-like protein binding#GO:0032182;binding#GO:0005488;ubiquitin binding#GO:0043130 cellular component biogenesis#GO:0044085;macroautophagy#GO:0016236;membrane organization#GO:0061024;protein catabolic process#GO:0030163;nucleus organization#GO:0006997;endomembrane system organization#GO:0010256;organonitrogen compound catabolic process#GO:1901565;modification-dependent macromolecule catabolic process#GO:0043632;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;membrane assembly#GO:0071709;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nuclear membrane organization#GO:0071763;cellular catabolic process#GO:0044248;cellular component assembly#GO:0022607;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;Golgi organization#GO:0007030;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular process#GO:0009987;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;membrane fusion#GO:0061025;organelle organization#GO:0006996;autophagosome assembly#GO:0000045;nuclear envelope organization#GO:0006998;autophagy#GO:0006914 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein-binding activity modulator#PC00095 CIOIN|Ensembl=ENSCING00000011966.1|UniProtKB=F6SKD3 F6SKD3 PTHR24369:SF211 ANTIGEN BSP, PUTATIVE-RELATED LEUCINE-RICH REPEAT-CONTAINING PROTEIN 15-LIKE cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 CIOIN|Ensembl=ENSCING00000009617.3|UniProtKB=F7ACX7 F7ACX7 LOC100187104 PTHR11977:SF131 VILLIN GELSOLIN-LIKE DOMAIN-CONTAINING PROTEIN cytoskeletal protein binding#GO:0008092;phosphatidylinositol bisphosphate binding#GO:1902936;small molecule binding#GO:0036094;phosphatidylinositol-4,5-bisphosphate binding#GO:0005546;binding#GO:0005488;actin filament binding#GO:0051015;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;lipid binding#GO:0008289;ion binding#GO:0043167;phosphatidylinositol binding#GO:0035091;anion binding#GO:0043168;phosphatidylinositol phosphate binding#GO:1901981;phospholipid binding#GO:0005543;actin binding#GO:0003779 negative regulation of protein polymerization#GO:0032272;negative regulation of protein depolymerization#GO:1901880;negative regulation of biological process#GO:0048519;negative regulation of actin filament depolymerization#GO:0030835;regulation of cellular component organization#GO:0051128;regulation of actin polymerization or depolymerization#GO:0008064;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;actin filament-based process#GO:0030029;regulation of protein-containing complex assembly#GO:0043254;regulation of biological quality#GO:0065008;regulation of cellular component biogenesis#GO:0044087;supramolecular fiber organization#GO:0097435;negative regulation of organelle organization#GO:0010639;negative regulation of protein-containing complex disassembly#GO:0043242;actin filament organization#GO:0007015;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;regulation of actin filament-based process#GO:0032970;barbed-end actin filament capping#GO:0051016;negative regulation of cellular component organization#GO:0051129;regulation of protein polymerization#GO:0032271;negative regulation of cellular process#GO:0048523;regulation of anatomical structure size#GO:0090066;regulation of actin filament length#GO:0030832;regulation of organelle organization#GO:0033043;regulation of actin filament organization#GO:0110053;actin polymerization or depolymerization#GO:0008154;regulation of protein-containing complex disassembly#GO:0043244;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of actin filament polymerization#GO:0030833;regulation of cellular component size#GO:0032535;negative regulation of supramolecular fiber organization#GO:1902904;regulation of supramolecular fiber organization#GO:1902903;cellular component organization or biogenesis#GO:0071840;regulation of protein depolymerization#GO:1901879;organelle organization#GO:0006996;regulation of actin filament depolymerization#GO:0030834;regulation of cellular process#GO:0050794;negative regulation of actin filament polymerization#GO:0030837;biological regulation#GO:0065007;negative regulation of protein-containing complex assembly#GO:0031333;actin cytoskeleton organization#GO:0030036;negative regulation of cytoskeleton organization#GO:0051494 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-motor actin binding protein#PC00165 CIOIN|Ensembl=ENSCING00000024743.1|UniProtKB=H2XWE7 H2XWE7 r35a PTHR10902:SF0 60S RIBOSOMAL PROTEIN L35A LARGE RIBOSOMAL SUBUNIT PROTEIN EL33 ribosomal protein#PC00202;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000024835.1|UniProtKB=H2XJQ5 H2XJQ5 LOC100183792 PTHR23097:SF181 TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER CASPASE-8-LIKE transmembrane signal receptor#PC00197 CIOIN|Ensembl=ENSCING00000014344.2|UniProtKB=F6TYZ7 F6TYZ7 PTHR14647:SF87 GALACTOSE-3-O-SULFOTRANSFERASE PUTATIVE-RELATED transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000019093.1|UniProtKB=F6WT44 F6WT44 LOC100187393 PTHR24264:SF65 TRYPSIN-RELATED SRCR DOMAIN-CONTAINING PROTEIN hydrolase activity#GO:0016787;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 serine protease#PC00203;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000012787.1|UniProtKB=F6XCN2 F6XCN2 LOC100177011 PTHR13323:SF4 LATE ENDOSOMAL/LYSOSOMAL MP1 INTERACTING PROTEIN RAGULATOR COMPLEX PROTEIN LAMTOR2 positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;cellular response to nitrogen compound#GO:1901699;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;positive regulation of TOR signaling#GO:0032008;regulation of signal transduction#GO:0009966;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;response to organonitrogen compound#GO:0010243;cellular process#GO:0009987;regulation of TOR signaling#GO:0032006;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cellular response to organonitrogen compound#GO:0071417;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007 CIOIN|Ensembl=ENSCING00000002263.3|UniProtKB=F6XLX0 F6XLX0 PTHR24345:SF91 SERINE/THREONINE-PROTEIN KINASE PLK SERINE_THREONINE-PROTEIN KINASE PLK4 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000003302.3|UniProtKB=A0A1W3JH18 A0A1W3JH18 kcc PTHR11827:SF73 SOLUTE CARRIER FAMILY 12, CATION COTRANSPORTERS KAZACHOC, ISOFORM G inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium ion transmembrane transporter activity#GO:0015079;symporter activity#GO:0015293;chloride transmembrane transporter activity#GO:0015108;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;active monoatomic ion transmembrane transporter activity#GO:0022853;monoatomic anion transmembrane transporter activity#GO:0008509;inorganic anion transmembrane transporter activity#GO:0015103;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294 inorganic ion homeostasis#GO:0098771;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;chloride transmembrane transport#GO:1902476;inorganic ion transmembrane transport#GO:0098660;cellular homeostasis#GO:0019725;inorganic anion transmembrane transport#GO:0098661;import across plasma membrane#GO:0098739;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;monoatomic cation transport#GO:0006812;inorganic anion transport#GO:0015698;potassium ion transport#GO:0006813;regulation of anatomical structure size#GO:0090066;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;monoatomic anion transmembrane transport#GO:0098656;chloride transport#GO:0006821;homeostatic process#GO:0042592;monoatomic cation homeostasis#GO:0055080;cellular component organization#GO:0016043;cellular process#GO:0009987;chemical homeostasis#GO:0048878;regulation of cellular component size#GO:0032535;monoatomic ion homeostasis#GO:0050801;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;regulation of cell size#GO:0008361;monoatomic ion transmembrane transport#GO:0034220;monoatomic anion transport#GO:0006820;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;import into cell#GO:0098657;potassium ion import across plasma membrane#GO:1990573 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000000722.3|UniProtKB=F6Q5A8 F6Q5A8 PTHR16027:SF9 DILUTE DOMAIN-CONTAINING PROTEIN YPR089W RAS-ASSOCIATING AND DILUTE DOMAIN-CONTAINING PROTEIN enzyme binding#GO:0019899;protein binding#GO:0005515;binding#GO:0005488 CIOIN|Ensembl=ENSCING00000022958.1|UniProtKB=H2Y0K5 H2Y0K5 PTHR48034:SF26 TRANSFORMER-2 SEX-DETERMINING PROTEIN-RELATED DAZ ASSOCIATED PROTEIN 1 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 positive regulation of gene expression#GO:0010628;positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of mRNA metabolic process#GO:1903313;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;biological regulation#GO:0065007;regulation of mRNA processing#GO:0050684;regulation of gene expression#GO:0010468;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule biosynthetic process#GO:0010556;regulation of mRNA splicing, via spliceosome#GO:0048024;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000020084.1|UniProtKB=H2XU06 H2XU06 PTHR19134:SF527 RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 7 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;protein tyrosine phosphatase activity#GO:0004725;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 protein phosphatase#PC00195;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000018087.1|UniProtKB=H2XRC2 H2XRC2 PTHR13826:SF14 INTESTINAL TREFOIL FACTOR-RELATED TREFOIL FACTOR 2 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 CIOIN|Ensembl=ENSCING00000004446.3|UniProtKB=F6XE89 F6XE89 PTHR31584:SF1 TUMOR PROTEIN P53-INDUCIBLE PROTEIN 11 TUMOR PROTEIN P53-INDUCIBLE PROTEIN 11 CIOIN|Ensembl=ENSCING00000009513.3|UniProtKB=F6XJ08 F6XJ08 LOC100185662 PTHR42918:SF9 LYSYL-TRNA SYNTHETASE LYSINE--TRNA LIGASE catalytic activity, acting on RNA#GO:0140098;tRNA binding#GO:0000049;ligase activity#GO:0016874;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;catalytic activity, acting on a nucleic acid#GO:0140640 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;peptide biosynthetic process#GO:0043043;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 aminoacyl-tRNA synthetase#PC00047;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000011448.2|UniProtKB=F7ACP0 F7ACP0 PTHR19277:SF161 PENTRAXIN LAMININ G DOMAIN-CONTAINING PROTEIN scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000003026.3|UniProtKB=F6QAI3 F6QAI3 PTHR16165:SF5 NXPE FAMILY MEMBER NXPE FAMILY MEMBER 3 CIOIN|Ensembl=ENSCING00000018384.1|UniProtKB=H2XP47 H2XP47 PTHR13809:SF27 GUANINE NUCLEOTIDE-BINDING PROTEIN GAMMA SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN SUBUNIT GAMMA protein binding#GO:0005515;binding#GO:0005488 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;plasma membrane protein complex#GO:0098797;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;cytoplasmic side of plasma membrane#GO:0009898;extrinsic component of membrane#GO:0019898;plasma membrane#GO:0005886 heterotrimeric G-protein#PC00117;G-protein#PC00020 Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>G-Protein#P01085;5HT2 type receptor mediated signaling pathway#P04374>G-protein#P04416;Cortocotropin releasing factor receptor signaling pathway#P04380>G-Protein#P04458;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>G-Protein#P01073;Metabotropic glutamate receptor group II pathway#P00040>G-protein#P01047 CIOIN|Ensembl=ENSCING00000003912.3|UniProtKB=F6TI55 F6TI55 PTHR12988:SF6 SPHINGOMYELIN PHOSPHODIESTERASE 4 SPHINGOMYELIN PHOSPHODIESTERASE 4 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;phosphoric diester hydrolase activity#GO:0008081;phospholipase activity#GO:0004620;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 lipid metabolic process#GO:0006629;organonitrogen compound catabolic process#GO:1901565;lipid catabolic process#GO:0016042;glycerophospholipid catabolic process#GO:0046475;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;lipid biosynthetic process#GO:0008610;sphingolipid metabolic process#GO:0006665;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;sphingolipid catabolic process#GO:0030149;cellular lipid catabolic process#GO:0044242;amide metabolic process#GO:0043603;sphingolipid biosynthetic process#GO:0030148;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;glycerophospholipid metabolic process#GO:0006650;cellular biosynthetic process#GO:0044249;glycerolipid catabolic process#GO:0046503;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;membrane lipid biosynthetic process#GO:0046467;ceramide metabolic process#GO:0006672;organophosphate catabolic process#GO:0046434;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;membrane lipid metabolic process#GO:0006643;ceramide biosynthetic process#GO:0046513;phospholipid catabolic process#GO:0009395;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255 phosphodiesterase#PC00185;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000005020.3|UniProtKB=F6TXQ6 F6TXQ6 PTHR42778:SF1 2-AMINOETHYLPHOSPHONATE--PYRUVATE TRANSAMINASE 2-AMINOETHYLPHOSPHONATE--PYRUVATE TRANSAMINASE transaminase#PC00216;transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000006781.3|UniProtKB=F6VEB2 F6VEB2 LOC100179970 PTHR19920:SF0 WD40 PROTEIN CIAO1 CYTOSOLIC IRON-SULFUR PROTEIN ASSEMBLY PROTEIN CIAO1-RELATED cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;iron-sulfur cluster assembly#GO:0016226;cellular component organization#GO:0016043;cellular process#GO:0009987 protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535 CIOIN|Ensembl=ENSCING00000014293.2|UniProtKB=F6VDJ9 F6VDJ9 PTHR11011:SF45 MALE STERILITY PROTEIN 2-RELATED FATTY ACYL-COA REDUCTASE CG8306-RELATED oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;lipid metabolic process#GO:0006629;heterocycle metabolic process#GO:0046483;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;acyl-CoA metabolic process#GO:0006637;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;amide metabolic process#GO:0043603;purine nucleotide metabolic process#GO:0006163;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;nucleobase-containing small molecule metabolic process#GO:0055086 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000019116.1|UniProtKB=H2XZU9 H2XZU9 LOC100185991 PTHR23350:SF0 PEROXISOME ASSEMBLY PROTEIN 10 PEROXISOME BIOGENESIS FACTOR 10 cellular localization#GO:0051641;intracellular protein transmembrane transport#GO:0065002;transmembrane transport#GO:0055085;macromolecule localization#GO:0033036;protein import into peroxisome matrix#GO:0016558;transport#GO:0006810;protein transmembrane transport#GO:0071806;nitrogen compound transport#GO:0071705;establishment of protein localization to organelle#GO:0072594;cellular component organization#GO:0016043;cellular process#GO:0009987;protein transmembrane import into intracellular organelle#GO:0044743;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;organelle organization#GO:0006996;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;protein localization to organelle#GO:0033365;peroxisome organization#GO:0007031 bounding membrane of organelle#GO:0098588;peroxisomal membrane#GO:0005778;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;peroxisome#GO:0005777;microbody#GO:0042579;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chaperone#PC00072 CIOIN|Ensembl=ENSCING00000024012.1|UniProtKB=H2XQR7 H2XQR7 PTHR43078:SF6 UDP-GLUCURONIC ACID DECARBOXYLASE-RELATED UDP-GLUCURONIC ACID DECARBOXYLASE 1 nucleotide binding#GO:0000166;carboxy-lyase activity#GO:0016831;carbon-carbon lyase activity#GO:0016830;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;lyase activity#GO:0016829;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 decarboxylase#PC00089;lyase#PC00144 CIOIN|Ensembl=ENSCING00000019252.1|UniProtKB=A0A1W5BA34 A0A1W5BA34 LOC100181796 PTHR11504:SF0 CYTOCHROME C OXIDASE POLYPEPTIDE VIA CYTOCHROME C OXIDASE SUBUNIT enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 mitochondrial ATP synthesis coupled electron transport#GO:0042775;aerobic respiration#GO:0009060;cellular respiration#GO:0045333;respiratory electron transport chain#GO:0022904;generation of precursor metabolites and energy#GO:0006091;aerobic electron transport chain#GO:0019646;oxidative phosphorylation#GO:0006119;electron transport chain#GO:0022900;ATP synthesis coupled electron transport#GO:0042773;cellular metabolic process#GO:0044237;cellular process#GO:0009987;mitochondrial electron transport, cytochrome c to oxygen#GO:0006123;energy derivation by oxidation of organic compounds#GO:0015980;metabolic process#GO:0008152 oxidase#PC00175;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000004605.3|UniProtKB=A0A1W2WAR8 A0A1W2WAR8 LOC100183249 PTHR23418:SF0 ACIREDUCTONE DIOXYGENASE ACIREDUCTONE DIOXYGENASE oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;dioxygenase activity#GO:0051213 oxoacid metabolic process#GO:0043436;proteinogenic amino acid metabolic process#GO:0170039;sulfur compound metabolic process#GO:0006790;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;alpha-amino acid metabolic process#GO:1901605;aspartate family amino acid metabolic process#GO:0009066;carboxylic acid metabolic process#GO:0019752;L-amino acid metabolic process#GO:0170033;amino acid metabolic process#GO:0006520;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152 oxygenase#PC00177;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000024311.1|UniProtKB=H2XYI5 H2XYI5 PTHR12385:SF14 CHOLINE TRANSPORTER-LIKE (SLC FAMILY 44) CHOLINE TRANSPORTER-LIKE 2 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 localization#GO:0051179;establishment of localization#GO:0051234;cellular process#GO:0009987;transmembrane transport#GO:0055085;transport#GO:0006810 cellular anatomical entity#GO:0110165;membrane#GO:0016020 secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000007316.3|UniProtKB=F6Z3E3 F6Z3E3 LOC100179743 PTHR21197:SF0 UDP-GALACTOPYRANOSE MUTASE UDP-GALACTOPYRANOSE MUTASE nucleotide binding#GO:0000166;small molecule binding#GO:0036094;intramolecular transferase activity#GO:0016866;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;flavin adenine dinucleotide binding#GO:0050660;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;isomerase activity#GO:0016853;ion binding#GO:0043167 mutase#PC00160 O-antigen biosynthesis#P02757>UDP-galacto-pyranose mutase#P03048 CIOIN|Ensembl=ENSCING00000017898.1|UniProtKB=H2Y299 H2Y299 zf(dhhc)-2 PTHR24166:SF48 ROLLING PEBBLES, ISOFORM B PROTEIN VAPYRIN scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000001128.3|UniProtKB=F6Z509 F6Z509 LOC100187247 PTHR12019:SF9 LAMINA-ASSOCIATED POLYPEPTIDE THYMOPOIETIN THYMOPOIETIN peptide hormone#PC00179 CIOIN|Ensembl=ENSCING00000023401.1|UniProtKB=H2XLF0 H2XLF0 LOC100186293 PTHR14453:SF67 PARP/ZINC FINGER CCCH TYPE DOMAIN CONTAINING PROTEIN POLY [ADP-RIBOSE] POLYMERASE molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714;protein-macromolecule adaptor activity#GO:0030674 negative regulation of gene expression#GO:0010629;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of biosynthetic process#GO:0009890;negative regulation of metabolic process#GO:0009892;regulation of biological process#GO:0050789;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000005380.3|UniProtKB=F7BEC5 F7BEC5 kcnq1 PTHR11537:SF274 VOLTAGE-GATED POTASSIUM CHANNEL POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY KQT MEMBER 1 monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;binding#GO:0005488;calmodulin binding#GO:0005516;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated potassium channel activity#GO:0005249;transporter activity#GO:0005215;channel activity#GO:0015267;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;protein binding#GO:0005515;monoatomic ion channel activity#GO:0005216;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion transmembrane transporter activity#GO:0015075 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;regulation of membrane potential#GO:0042391;action potential#GO:0001508;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;localization#GO:0051179;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;export from cell#GO:0140352;potassium ion transport#GO:0006813 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;voltage-gated potassium channel complex#GO:0008076;cation channel complex#GO:0034703;plasma membrane#GO:0005886 transporter#PC00227;voltage-gated ion channel#PC00241 CIOIN|Ensembl=ENSCING00000009750.3|UniProtKB=F7ABX1 F7ABX1 LOC100185339 PTHR11256:SF48 BCL-2 RELATED BCL-2-RELATED OVARIAN KILLER PROTEIN protein binding#GO:0005515;binding#GO:0005488 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0043280;intrinsic apoptotic signaling pathway in response to DNA damage#GO:0008630;signal transduction#GO:0007165;positive regulation of cysteine-type endopeptidase activity#GO:2001056;regulation of protein metabolic process#GO:0051246;apoptotic mitochondrial changes#GO:0008637;regulation of cysteine-type endopeptidase activity#GO:2000116;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;positive regulation of proteolysis#GO:0045862;regulation of biological process#GO:0050789;activation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0006919;DNA damage response#GO:0006974;positive regulation of metabolic process#GO:0009893;regulation of molecular function#GO:0065009;apoptotic process#GO:0006915;cell death#GO:0008219;regulation of hydrolase activity#GO:0051336;mitochondrion organization#GO:0007005;intracellular signal transduction#GO:0035556;positive regulation of biological process#GO:0048518;positive regulation of peptidase activity#GO:0010952;signaling#GO:0023052;regulation of proteolysis#GO:0030162;cellular response to stimulus#GO:0051716;positive regulation of catalytic activity#GO:0043085;programmed cell death#GO:0012501;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of hydrolase activity#GO:0051345;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;intrinsic apoptotic signaling pathway#GO:0097193;apoptotic signaling pathway#GO:0097190;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;response to stress#GO:0006950;extrinsic apoptotic signaling pathway#GO:0097191;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of endopeptidase activity#GO:0052548;regulation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0043281;regulation of peptidase activity#GO:0052547;release of cytochrome c from mitochondria#GO:0001836;cellular response to stress#GO:0033554;positive regulation of endopeptidase activity#GO:0010950;regulation of metabolic process#GO:0019222 bounding membrane of organelle#GO:0098588;envelope#GO:0031975;mitochondrial membrane#GO:0031966;mitochondrial outer membrane#GO:0005741;intracellular membrane-bounded organelle#GO:0043231;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867 Apoptosis signaling pathway#P00006>Bok#P00261 CIOIN|Ensembl=ENSCING00000004962.3|UniProtKB=F6WLA0 F6WLA0 PTHR43715:SF1 GDP-MANNOSE 4,6-DEHYDRATASE GDP-MANNOSE 4,6 DEHYDRATASE dehydratase#PC00091;lyase#PC00144 Mannose metabolism#P02752>GDP-Mannose 4,6-dehydratase#P03015 CIOIN|Ensembl=ENSCING00000021967.1|UniProtKB=H2XM96 H2XM96 PTHR13295:SF4 GLUTAMATE CYSTEINE LIGASE REGULATORY SUBUNIT GLUTAMATE--CYSTEINE LIGASE REGULATORY SUBUNIT enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 sulfur compound metabolic process#GO:0006790;positive regulation of catalytic activity#GO:0043085;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;positive regulation of molecular function#GO:0044093;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;glutathione metabolic process#GO:0006749;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;regulation of molecular function#GO:0065009;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;cellular modified amino acid metabolic process#GO:0006575;biological regulation#GO:0065007;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622 ligase#PC00142;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000006731.3|UniProtKB=F6YKX8 F6YKX8 LOC100177118 PTHR11363:SF5 60S RIBOSOMAL PROTEIN L3-RELATED LARGE RIBOSOMAL SUBUNIT PROTEIN UL3 structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;structural molecule activity#GO:0005198;binding#GO:0005488;organic cyclic compound binding#GO:0097159 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic large ribosomal subunit#GO:0022625;large ribosomal subunit#GO:0015934;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000023642.1|UniProtKB=H2XLC9 H2XLC9 LOC100178257 PTHR33802:SF1 SI:CH211-161H7.5-RELATED XK-RELATED PROTEIN CIOIN|Ensembl=ENSCING00000006880.3|UniProtKB=F6Y9W3 F6Y9W3 PTHR11616:SF241 SODIUM/CHLORIDE DEPENDENT TRANSPORTER SODIUM- AND CHLORIDE-DEPENDENT GLYCINE TRANSPORTER 2 inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;organic acid:sodium symporter activity#GO:0005343;organic acid transmembrane transporter activity#GO:0005342;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;organic anion transmembrane transporter activity#GO:0008514;monoatomic cation transmembrane transporter activity#GO:0008324;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;amino acid:sodium symporter activity#GO:0005283;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;metal ion transmembrane transporter activity#GO:0046873;active monoatomic ion transmembrane transporter activity#GO:0022853;amino acid transmembrane transporter activity#GO:0015171;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;organic anion transport#GO:0015711;amino acid transport#GO:0006865;organic acid transport#GO:0015849;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;amino acid import across plasma membrane#GO:0089718;carboxylic acid transmembrane transport#GO:1905039;localization#GO:0051179;organic substance transport#GO:0071702;import across plasma membrane#GO:0098739;amino acid transmembrane transport#GO:0003333;sodium ion transport#GO:0006814;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transport#GO:0006812;organic acid transmembrane transport#GO:1903825;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;import into cell#GO:0098657;sodium ion transmembrane transport#GO:0035725 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 primary active transporter#PC00068;transporter#PC00227 CIOIN|Ensembl=ENSCING00000002023.3|UniProtKB=Q4H3S1 Q4H3S1 Ci-COUP PTHR24083:SF46 NUCLEAR HORMONE RECEPTOR STEROID RECEPTOR SEVEN-UP, ISOFORM A cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;signaling receptor activity#GO:0038023;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular transducer activity#GO:0060089;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C4 zinc finger nuclear receptor#PC00169;zinc finger transcription factor#PC00244 CIOIN|Ensembl=ENSCING00000000891.3|UniProtKB=F6UPC7 F6UPC7 LOC100181568 PTHR23105:SF101 RIBOSOMAL PROTEIN L7AE FAMILY MEMBER LARGE RIBOSOMAL SUBUNIT PROTEIN UL1 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic large ribosomal subunit#GO:0022625;large ribosomal subunit#GO:0015934;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202 CIOIN|Ensembl=ENSCING00000024509.1|UniProtKB=H2XX05 H2XX05 PTHR23226:SF375 ZINC FINGER AND SCAN DOMAIN-CONTAINING C2H2-TYPE DOMAIN-CONTAINING PROTEIN-RELATED sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 CIOIN|Ensembl=ENSCING00000005058.3|UniProtKB=F7A5A0 F7A5A0 LOC100183816 PTHR10540:SF6 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT F-RELATED EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT F nucleic acid binding#GO:0003676;translation initiation factor binding#GO:0031369;translation regulator activity#GO:0045182;binding#GO:0005488;organic cyclic compound binding#GO:0097159;translation initiation factor activity#GO:0003743;protein binding#GO:0005515;translation regulator activity, nucleic acid binding#GO:0090079;translation factor activity, RNA binding#GO:0008135 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;translational initiation#GO:0006413;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;eukaryotic translation initiation factor 3 complex#GO:0005852;intracellular anatomical structure#GO:0005622 translation initiation factor#PC00224;translation factor#PC00223 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489;Cell cycle#P00013>Proteasome#P00480 CIOIN|Ensembl=ENSCING00000019172.1|UniProtKB=H2Y3I1 H2Y3I1 PTHR46454:SF18 DYNEIN AXONEMAL HEAVY CHAIN 7-RELATED DYNEIN HEAVY CHAIN REGION D6 P-LOOP DOMAIN-CONTAINING PROTEIN microtubule or microtubule-binding cytoskeletal protein#PC00157 CIOIN|Ensembl=ENSCING00000004503.3|UniProtKB=F7ATS3 F7ATS3 LOC100186237 PTHR45937:SF1 ASPARAGINE SYNTHETASE DOMAIN-CONTAINING PROTEIN 1 ASPARAGINE SYNTHETASE DOMAIN-CONTAINING PROTEIN 1 CIOIN|Ensembl=ENSCING00000022724.1|UniProtKB=H2Y323 H2Y323 LOC100176662 PTHR13931:SF2 UBIQUITINATION FACTOR E4 UBIQUITIN CONJUGATION FACTOR E4 B transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 macromolecule modification#GO:0043412;protein catabolic process#GO:0030163;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;post-translational protein modification#GO:0043687;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;protein polyubiquitination#GO:0000209;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;protein ubiquitination#GO:0016567;macromolecule catabolic process#GO:0009057;response to endoplasmic reticulum stress#GO:0034976;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;ERAD pathway#GO:0036503;response to organonitrogen compound#GO:0010243;cellular process#GO:0009987;primary metabolic process#GO:0044238;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;cellular response to stress#GO:0033554 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000000315.3|UniProtKB=F6YXT8 F6YXT8 LOC100184027 PTHR12189:SF2 MRNA GUANINE-7- METHYLTRANSFERASE MRNA CAP GUANINE-N7 METHYLTRANSFERASE catalytic activity, acting on RNA#GO:0140098;N-methyltransferase activity#GO:0008170;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;RNA methyltransferase activity#GO:0008173 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;mRNA processing#GO:0006397;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031;RNA methyltransferase#PC00033 CIOIN|Ensembl=ENSCING00000013155.2|UniProtKB=F6YXW3 F6YXW3 PTHR15228:SF25 SPERMATHECAL PHYSIOLOGY VARIANT F-BAR DOMAIN-CONTAINING PROTEIN nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 regulation of molecular function#GO:0065009;regulation of GTPase activity#GO:0043087;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;activation of GTPase activity#GO:0090630;biological regulation#GO:0065007;positive regulation of molecular function#GO:0044093;regulation of hydrolase activity#GO:0051336;regulation of catalytic activity#GO:0050790;positive regulation of hydrolase activity#GO:0051345 G-protein modulator#PC00022;GTPase-activating protein#PC00257 CIOIN|Ensembl=ENSCING00000002723.3|UniProtKB=F6UCW1 F6UCW1 LOC100187015 PTHR12983:SF9 RING FINGER 10 FAMILY MEMBER E3 UBIQUITIN-PROTEIN LIGASE RNF10 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of RNA metabolic process#GO:0051254;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 CIOIN|Ensembl=ENSCING00000021267.1|UniProtKB=H2XYE6 H2XYE6 PTHR12835:SF5 BIOTIN PROTEIN LIGASE BIOTIN--PROTEIN LIGASE ligase activity#GO:0016874;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ligase#PC00142;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000012504.2|UniProtKB=F6S5U6 F6S5U6 PTHR24412:SF500 KELCH PROTEIN CHROMOSOME UNDETERMINED SCAFFOLD_42, WHOLE GENOME SHOTGUN SEQUENCE scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000000421.3|UniProtKB=F7BL16 F7BL16 isl PTHR24204:SF8 INSULIN GENE ENHANCER PROTEIN TAILUP, ISOFORM A cellular developmental process#GO:0048869;neurogenesis#GO:0022008;cell projection organization#GO:0030030;multicellular organism development#GO:0007275;developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;cell fate commitment#GO:0045165;cellular process#GO:0009987;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cellular anatomical entity morphogenesis#GO:0032989;cell fate specification#GO:0001708;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;cell differentiation#GO:0030154;system development#GO:0048731;neuron projection development#GO:0031175;axon development#GO:0061564;cell morphogenesis involved in neuron differentiation#GO:0048667;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;neuron differentiation#GO:0030182;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;axonogenesis#GO:0007409;plasma membrane bounded cell projection morphogenesis#GO:0120039;generation of neurons#GO:0048699 CIOIN|Ensembl=ENSCING00000005889.3|UniProtKB=F6WJH6 F6WJH6 PTHR13847:SF200 SARCOSINE DEHYDROGENASE-RELATED SARCOSINE DEHYDROGENASE, MITOCHONDRIAL oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 oxoacid metabolic process#GO:0043436;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;amino acid catabolic process#GO:0009063;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;nitrogen compound metabolic process#GO:0006807;cellular modified amino acid metabolic process#GO:0006575;alpha-amino acid metabolic process#GO:1901605;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;carboxylic acid metabolic process#GO:0019752;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 dehydrogenase#PC00092;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000002830.3|UniProtKB=F6WYT3 F6WYT3 PTHR12586:SF1 CDP-DIACYLGLYCEROL--SERINE O-PHOSPHATIDYLTRANSFERASE CDP-DIACYLGLYCEROL--GLYCEROL-3-PHOSPHATE 3-PHOSPHATIDYLTRANSFERASE, MITOCHONDRIAL transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000019520.1|UniProtKB=Q4H2R5 Q4H2R5 Ci-SPT4 PTHR12882:SF1 SUPPRESSOR OF TY 4 TRANSCRIPTION ELONGATION FACTOR SPT4 basal RNA polymerase II transcription machinery binding#GO:0001099;RNA polymerase binding#GO:0070063;binding#GO:0005488;RNA polymerase core enzyme binding#GO:0043175;RNA polymerase II complex binding#GO:0000993;protein binding#GO:0005515;enzyme binding#GO:0019899;basal transcription machinery binding#GO:0001098 cellular aromatic compound metabolic process#GO:0006725;DNA-templated transcription#GO:0006351;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;DNA-templated transcription elongation#GO:0006354;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;RNA biosynthetic process#GO:0032774;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nucleobase-containing compound biosynthetic process#GO:0034654;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;aromatic compound biosynthetic process#GO:0019438;transcription elongation by RNA polymerase II#GO:0006368;transcription by RNA polymerase II#GO:0006366;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;transcription elongation factor complex#GO:0008023;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031;general transcription factor#PC00259 CIOIN|Ensembl=ENSCING00000012939.2|UniProtKB=F6RH63 F6RH63 PTHR10845:SF259 REGULATOR OF G PROTEIN SIGNALING RGS DOMAIN-CONTAINING PROTEIN-RELATED G-protein modulator#PC00022;protein-binding activity modulator#PC00095;GTPase-activating protein#PC00257 CIOIN|Ensembl=ENSCING00000000677.3|UniProtKB=F6QSB8 F6QSB8 LOC100182061 PTHR11571:SF150 GLUTATHIONE S-TRANSFERASE GLUTATHIONE S-TRANSFERASE glutathione transferase activity#GO:0004364;transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824 sulfur compound metabolic process#GO:0006790;nitrogen compound metabolic process#GO:0006807;peptide metabolic process#GO:0006518;cellular modified amino acid metabolic process#GO:0006575;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular process#GO:0009987;glutathione metabolic process#GO:0006749;amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000016837.2|UniProtKB=F6QC95 F6QC95 PTHR13869:SF24 MYELIN P0 RELATED BASEMENT MEMBRANE-SPECIFIC HEPARAN SULFATE PROTEOGLYCAN CORE PROTEIN-LIKE myelin protein#PC00161;structural protein#PC00211 CIOIN|Ensembl=ENSCING00000005629.3|UniProtKB=F7ASK1 F7ASK1 LOC100177721 PTHR13720:SF14 WD-40 REPEAT PROTEIN CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 52 cytoskeletal protein#PC00085;microtubule or microtubule-binding cytoskeletal protein#PC00157 CIOIN|Ensembl=ENSCING00000018352.1|UniProtKB=H2XNF7 H2XNF7 PTHR19300:SF61 BETA-1,4-GALACTOSYLTRANSFERASE BETA-1,4-N-ACETYLGALACTOSAMINYLTRANSFERASE galactosyltransferase activity#GO:0008378;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 glycosylation#GO:0070085;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000024610.1|UniProtKB=H2XRC1 H2XRC1 PTHR14256:SF3 NADH-UBIQUINONE OXIDOREDUCTASE MLRQ SUBUNIT NORMAL MUCOSA OF ESOPHAGUS-SPECIFIC GENE 1 PROTEIN envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;respiratory chain complex#GO:0098803;cytochrome complex#GO:0070069;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;respirasome#GO:0070469;protein-containing complex#GO:0032991;mitochondrial envelope#GO:0005740;inner mitochondrial membrane protein complex#GO:0098800;mitochondrial respirasome#GO:0005746;membrane-bounded organelle#GO:0043227;respiratory chain complex IV#GO:0045277;mitochondrial protein-containing complex#GO:0098798 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000023918.1|UniProtKB=Q1RL57 Q1RL57 Ci-ZF(MYND)-8 PTHR10237:SF14 DEFORMED EPIDERMAL AUTOREGULATORY FACTOR 1 HOMOLOG SUPPRESSIN MYND-TYPE DOMAIN-CONTAINING PROTEIN transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 zinc finger transcription factor#PC00244 CIOIN|Ensembl=ENSCING00000008217.3|UniProtKB=F6RU53 F6RU53 PTHR13793:SF164 PHD FINGER PROTEINS ALHAMBRA, ISOFORM P nucleosome binding#GO:0031491;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;chromatin binding#GO:0003682;histone binding#GO:0042393 regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 zinc finger transcription factor#PC00244 CIOIN|Ensembl=ENSCING00000016548.2|UniProtKB=F6VGB1 F6VGB1 PTHR23382:SF1 MALATE DEHYDROGENASE MALATE DEHYDROGENASE 1B-RELATED oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 cellular aromatic compound metabolic process#GO:0006725;dicarboxylic acid metabolic process#GO:0043648;pyridine nucleotide metabolic process#GO:0019362;nucleobase-containing compound metabolic process#GO:0006139;energy derivation by oxidation of organic compounds#GO:0015980;phosphorus metabolic process#GO:0006793;tricarboxylic acid cycle#GO:0006099;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;pyridine-containing compound metabolic process#GO:0072524;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular respiration#GO:0045333;aerobic respiration#GO:0009060;oxoacid metabolic process#GO:0043436;generation of precursor metabolites and energy#GO:0006091;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;nicotinamide nucleotide metabolic process#GO:0046496;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;carboxylic acid metabolic process#GO:0019752;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 dehydrogenase#PC00092;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000019394.1|UniProtKB=H2XZJ6 H2XZJ6 PTHR13395:SF6 SISTER CHROMATID COHESION PROTEIN DCC1-RELATED SISTER CHROMATID COHESION PROTEIN DCC1 cellular component organization or biogenesis#GO:0071840;sister chromatid cohesion#GO:0007062;mitotic sister chromatid cohesion#GO:0007064;organelle organization#GO:0006996;chromosome organization#GO:0051276;cell cycle process#GO:0022402;cell cycle#GO:0007049;cellular component organization#GO:0016043;cellular process#GO:0009987 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-DNA complex#GO:0032993;chromatin#GO:0000785;chromosome, centromeric region#GO:0000775;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;chromosomal region#GO:0098687;nuclear protein-containing complex#GO:0140513 DNA metabolism protein#PC00009;replication origin binding protein#PC00199 CIOIN|Ensembl=ENSCING00000021218.1|UniProtKB=H2XT55 H2XT55 PTHR21435:SF1 MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM29 MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM29 cellular localization#GO:0051641;protein insertion into mitochondrial inner membrane#GO:0045039;macromolecule localization#GO:0033036;membrane organization#GO:0061024;transport#GO:0006810;nitrogen compound transport#GO:0071705;establishment of protein localization#GO:0045184;organic substance transport#GO:0071702;establishment of protein localization to membrane#GO:0090150;establishment of localization#GO:0051234;protein targeting to mitochondrion#GO:0006626;mitochondrion organization#GO:0007005;protein localization to organelle#GO:0033365;localization within membrane#GO:0051668;protein localization to membrane#GO:0072657;protein targeting#GO:0006605;establishment of protein localization to organelle#GO:0072594;cellular component organization#GO:0016043;cellular process#GO:0009987;protein localization to mitochondrion#GO:0070585;protein localization#GO:0008104;inner mitochondrial membrane organization#GO:0007007;mitochondrial transport#GO:0006839;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;organelle organization#GO:0006996;establishment of protein localization to mitochondrion#GO:0072655;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;mitochondrial membrane organization#GO:0007006 envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial envelope#GO:0005740;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227;mitochondrial protein-containing complex#GO:0098798 CIOIN|Ensembl=ENSCING00000008049.3|UniProtKB=F6S4V6 F6S4V6 PTHR45870:SF2 TUBULIN MONOGLYCYLASE TTLL3 TUBULIN MONOGLYCYLASE TTLL3 ligase activity#GO:0016874;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000013776.1|UniProtKB=F6RFD4 F6RFD4 PTHR16165:SF5 NXPE FAMILY MEMBER NXPE FAMILY MEMBER 3 CIOIN|Ensembl=ENSCING00000022101.1|UniProtKB=H2XVR3 H2XVR3 LOC100180565 PTHR12652:SF50 PEROXISOMAL BIOGENESIS FACTOR 11 PEROXIN 11 cellular component organization or biogenesis#GO:0071840;organelle fission#GO:0048285;cellular component organization#GO:0016043;cellular process#GO:0009987;organelle organization#GO:0006996;peroxisome organization#GO:0007031 peroxisomal membrane#GO:0005778;cytoplasm#GO:0005737;bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;microbody#GO:0042579;peroxisome#GO:0005777;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000013523.2|UniProtKB=F7B0Z3 F7B0Z3 PTHR19444:SF13 UNC-93 RELATED PROTEIN UNC-93 HOMOLOG A membrane-bound signaling molecule#PC00152 CIOIN|Ensembl=ENSCING00000003802.3|UniProtKB=F6ZTL8 F6ZTL8 PTHR23233:SF84 SAL-LIKE PROTEIN FI23031P1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 CIOIN|Ensembl=ENSCING00000014562.2|UniProtKB=F6UZ38 F6UZ38 PTHR45704:SF15 RAS-LIKE FAMILY MEMBER 11 SMALL MONOMERIC GTPASE CIOIN|Ensembl=ENSCING00000020724.1|UniProtKB=H2XLZ4 H2XLZ4 PTHR11829:SF388 FORKHEAD BOX PROTEIN FORK HEAD DOMAIN-CONTAINING PROTEIN L1-RELATED sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;anatomical structure morphogenesis#GO:0009653;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 CIOIN|Ensembl=ENSCING00000017452.2|UniProtKB=A0A1W2WCG1 A0A1W2WCG1 LOC108949278 PTHR10064:SF0 60S RIBOSOMAL PROTEIN L22 FI24544P1-RELATED structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;structural molecule activity#GO:0005198;binding#GO:0005488;organic cyclic compound binding#GO:0097159 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cytoplasmic translation#GO:0002181;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;translation#GO:0006412;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 ribosomal protein#PC00202;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000003970.3|UniProtKB=F6Z2T6 F6Z2T6 LOC100180182 PTHR31501:SF7 CALCIUM RELEASE-ACTIVATED CALCIUM CHANNEL PROTEIN 1 CALCIUM RELEASE-ACTIVATED CALCIUM CHANNEL PROTEIN 1 ion channel#PC00133;transporter#PC00227 CIOIN|Ensembl=ENSCING00000017293.2|UniProtKB=F7A0C5 F7A0C5 PTHR15197:SF0 COILIN P80 COILIN nucleic acid binding#GO:0003676;RNA binding#GO:0003723;snRNA binding#GO:0017069;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;RNA processing#GO:0006396;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;protein-RNA complex assembly#GO:0022618;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;spliceosomal snRNP assembly#GO:0000387;organic substance metabolic process#GO:0071704;mRNA splicing, via spliceosome#GO:0000398;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;protein-containing complex organization#GO:0043933;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;ribonucleoprotein complex biogenesis#GO:0022613;mRNA processing#GO:0006397;protein-RNA complex organization#GO:0071826;RNA splicing, via transesterification reactions#GO:0000375 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear body#GO:0016604;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA metabolism protein#PC00009 CIOIN|Ensembl=ENSCING00000023499.1|UniProtKB=H2XX63 H2XX63 PTHR13030:SF8 NUDIX HYDROLASE ADP-RIBOSE PYROPHOSPHATASE, MITOCHONDRIAL metabolite interconversion enzyme#PC00262;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000011466.2|UniProtKB=H2XMQ8 H2XMQ8 PTHR11787:SF4 RAB GDP-DISSOCIATION INHIBITOR CHM, RAB ESCORT PROTEIN 1 localization#GO:0051179;establishment of localization#GO:0051234;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;transport#GO:0006810;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;vesicle-mediated transport#GO:0016192;cellular metabolic process#GO:0044237;cellular process#GO:0009987;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 G-protein modulator#PC00022;protein-binding activity modulator#PC00095 CIOIN|Ensembl=ENSCING00000019577.1|UniProtKB=H2XWE8 H2XWE8 LOC100177985 PTHR10165:SF103 LIPID PHOSPHATE PHOSPHATASE PHOSPHOLIPID PHOSPHATASE HOMOLOG 1.2 HOMOLOG hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 phospholipid dephosphorylation#GO:0046839;lipid metabolic process#GO:0006629;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cellular metabolic process#GO:0044237;cell communication#GO:0007154;lipid modification#GO:0030258;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;dephosphorylation#GO:0016311;biological regulation#GO:0065007;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;signaling#GO:0023052;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 phosphatase#PC00181;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000022396.1|UniProtKB=H2XW37 H2XW37 PTHR21522:SF32 PROTON CHANNEL OTOP OTOPETRIN-2 monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;proton transmembrane transporter activity#GO:0015078;proton channel activity#GO:0015252;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267;monoatomic ion channel activity#GO:0005216 localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;proton transmembrane transport#GO:1902600;monoatomic ion transmembrane transport#GO:0034220;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;monoatomic cation transport#GO:0006812;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655 cellular anatomical entity#GO:0110165;membrane#GO:0016020 transporter#PC00227 CIOIN|Ensembl=ENSCING00000010055.3|UniProtKB=F6VUF1 F6VUF1 PTHR12027:SF91 WNT RELATED PROTO-ONCOGENE WNT-1 molecular function activator activity#GO:0140677;binding#GO:0005488;molecular function regulator activity#GO:0098772;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;cytokine activity#GO:0005125;G protein-coupled receptor binding#GO:0001664;signaling receptor binding#GO:0005102 cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;neurogenesis#GO:0022008;developmental process#GO:0032502;multicellular organism development#GO:0007275;cell communication#GO:0007154;cell fate commitment#GO:0045165;cell-cell signaling by wnt#GO:0198738;nervous system development#GO:0007399;cellular process#GO:0009987;regulation of biological process#GO:0050789;system development#GO:0048731;response to stimulus#GO:0050896;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;neuron differentiation#GO:0030182;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;cell-cell signaling#GO:0007267;signaling#GO:0023052;canonical Wnt signaling pathway#GO:0060070;Wnt signaling pathway#GO:0016055 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 intercellular signal molecule#PC00207 Wnt signaling pathway#P00057>Wnt#P01444;Alzheimer disease-presenilin pathway#P00004>Wnt#P00142;Angiogenesis#P00005>Wnt#P00206;Cadherin signaling pathway#P00012>Wnt#P00474 CIOIN|Ensembl=ENSCING00000006577.3|UniProtKB=F6R1D0 F6R1D0 LOC100178790 PTHR34524:SF15 CALCYPHOSIN EF-HAND DOMAIN-CONTAINING PROTEIN calmodulin-related#PC00061 CIOIN|Ensembl=ENSCING00000003869.3|UniProtKB=F6XGT0 F6XGT0 LOC100185418 PTHR11711:SF427 ADP RIBOSYLATION FACTOR-RELATED ADP-RIBOSYLATION FACTOR carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167 cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 G-protein#PC00020 CIOIN|Ensembl=ENSCING00000022415.1|UniProtKB=H2XUJ8 H2XUJ8 LOC100175328 PTHR14336:SF15 TANDEM PH DOMAIN CONTAINING PROTEIN DUAL ADAPTER FOR PHOSPHOTYROSINE AND 3-PHOSPHOTYROSINE AND 3-PHOSPHOINOSITIDE CIOIN|Ensembl=ENSCING00000002035.3|UniProtKB=F6TGA3 F6TGA3 PTHR35170:SF1 PROTEIN DD3-3 PROTEIN DD3-3 CIOIN|Ensembl=ENSCING00000006531.3|UniProtKB=F6PH17 F6PH17 PTHR11214:SF394 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE HEXOSYLTRANSFERASE transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;protein O-linked glycosylation#GO:0006493;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;aminoglycan biosynthetic process#GO:0006023;aminoglycan metabolic process#GO:0006022;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 bounding membrane of organelle#GO:0098588;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;Golgi membrane#GO:0000139;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111 CIOIN|Ensembl=ENSCING00000005342.3|UniProtKB=F7B5A5 F7B5A5 PTHR10997:SF9 IMPORTIN-7, 8, 11 IMPORTIN-9 cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;protein localization to nucleus#GO:0034504;nitrogen compound transport#GO:0071705;establishment of protein localization to organelle#GO:0072594;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;protein import into nucleus#GO:0006606;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;protein localization to organelle#GO:0033365;intracellular transport#GO:0046907;nuclear transport#GO:0051169;import into nucleus#GO:0051170 envelope#GO:0031975;cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear envelope#GO:0005635;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transporter#PC00227 CIOIN|Ensembl=ENSCING00000006981.3|UniProtKB=F6SYI7 F6SYI7 LOC100183100 PTHR30543:SF21 CHROMATE REDUCTASE NAD(P)H-DEPENDENT FMN REDUCTASE LOT6 nucleotide binding#GO:0000166;carbohydrate derivative binding#GO:0097367;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;anion binding#GO:0043168 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000019005.1|UniProtKB=F6QK12 F6QK12 PTHR24264:SF54 TRYPSIN-RELATED PEPTIDASE S1 DOMAIN-CONTAINING PROTEIN hydrolase activity#GO:0016787;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 serine protease#PC00203;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000000348.3|UniProtKB=F6WDR9 F6WDR9 tgfbr-iia PTHR23255:SF98 TRANSFORMING GROWTH FACTOR-BETA RECEPTOR TYPE I AND II SERINE_THREONINE-PROTEIN KINASE RECEPTOR signaling receptor activity#GO:0038023;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;protein kinase activity#GO:0004672;transmembrane signaling receptor activity#GO:0004888;transferase activity#GO:0016740;transmembrane receptor protein kinase activity#GO:0019199;transmembrane receptor protein serine/threonine kinase activity#GO:0004675;protein serine/threonine kinase activity#GO:0004674;molecular transducer activity#GO:0060089;activin binding#GO:0048185;protein-containing complex binding#GO:0044877;catalytic activity, acting on a protein#GO:0140096 signal transduction#GO:0007165;macromolecule modification#GO:0043412;response to growth factor#GO:0070848;protein modification process#GO:0036211;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;response to endogenous stimulus#GO:0009719;nitrogen compound metabolic process#GO:0006807;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;cellular response to endogenous stimulus#GO:0071495;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cell communication#GO:0007154;cellular process#GO:0009987;activin receptor signaling pathway#GO:0032924;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;cellular response to growth factor stimulus#GO:0071363;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007 receptor complex#GO:0043235;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;plasma membrane signaling receptor complex#GO:0098802;catalytic complex#GO:1902494;transferase complex#GO:1990234;plasma membrane protein complex#GO:0098797;serine/threonine protein kinase complex#GO:1902554;protein kinase complex#GO:1902911;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;transferase complex, transferring phosphorus-containing groups#GO:0061695 serine/threonine protein kinase receptor#PC00205 GBB signaling pathway#P06214>PUT#P06304;DPP signaling pathway#P06213>PUT#P06277;ALP23B signaling pathway#P06209>PUT#P06218;BMP/activin signaling pathway-drosophila#P06211>TGFbetaR II#P06255;TGF-beta signaling pathway#P00052>TGFbetareceptors#P01283;SCW signaling pathway#P06216>PUT#P06320;TGF-beta signaling pathway#P00052>TGFbetareceptor II#P01277;Activin beta signaling pathway#P06210>PUT#P06229;DPP-SCW signaling pathway#P06212>PUT#P06270 CIOIN|Ensembl=ENSCING00000008013.3|UniProtKB=F6VH72 F6VH72 PTHR12967:SF0 PROTEIN SHQ1 HOMOLOG PROTEIN SHQ1 HOMOLOG protein binding#GO:0005515;unfolded protein binding#GO:0051082;binding#GO:0005488 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;protein-RNA complex assembly#GO:0022618;cellular component biogenesis#GO:0044085;protein-containing complex organization#GO:0043933;ribonucleoprotein complex biogenesis#GO:0022613;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;protein-RNA complex organization#GO:0071826;cellular process#GO:0009987 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000024695.1|UniProtKB=F6XU26 F6XU26 ci-zf(c3h_u1like)-1 PTHR16465:SF0 NUCLEASE-RELATED ZINC FINGER MATRIN-TYPE PROTEIN 5 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;U12-type spliceosomal complex#GO:0005689;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000019036.1|UniProtKB=H2XUX7 H2XUX7 PTHR19444:SF13 UNC-93 RELATED PROTEIN UNC-93 HOMOLOG A membrane-bound signaling molecule#PC00152 CIOIN|Ensembl=ENSCING00000009015.3|UniProtKB=H2XZE5 H2XZE5 PTHR15574:SF40 WD REPEAT DOMAIN-CONTAINING FAMILY WD AND TETRATRICOPEPTIDE REPEATS PROTEIN 1 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of biosynthetic process#GO:0009890;negative regulation of metabolic process#GO:0009892;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of cellular process#GO:0050794;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of lipid metabolic process#GO:0019216;regulation of lipid biosynthetic process#GO:0046890;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;negative regulation of cellular biosynthetic process#GO:0031327 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;cullin-RING ubiquitin ligase complex#GO:0031461;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;Cul4-RING E3 ubiquitin ligase complex#GO:0080008 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000012540.2|UniProtKB=F7AUG3 F7AUG3 PTHR11214:SF283 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE N-ACETYLLACTOSAMINIDE BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE 4-LIKE transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;protein O-linked glycosylation#GO:0006493;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 bounding membrane of organelle#GO:0098588;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;Golgi membrane#GO:0000139;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111 CIOIN|Ensembl=ENSCING00000014075.2|UniProtKB=F6SCX5 F6SCX5 tgfbr-ic PTHR23255:SF71 TRANSFORMING GROWTH FACTOR-BETA RECEPTOR TYPE I AND II RECEPTOR PROTEIN SERINE_THREONINE KINASE transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular response to endogenous stimulus#GO:0071495;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;response to growth factor#GO:0070848;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;response to stimulus#GO:0050896;response to endogenous stimulus#GO:0009719;cellular response to growth factor stimulus#GO:0071363;nitrogen compound metabolic process#GO:0006807;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 receptor complex#GO:0043235;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 serine/threonine protein kinase receptor#PC00205 Wnt signaling pathway#P00057>TGFbetaactivated Kinase-1#P01442;Activin beta signaling pathway#P06210>BABO#P06231;ALP23B signaling pathway#P06209>BABO#P06220;MYO signaling pathway#P06215>BABO#P06310;TGF-beta signaling pathway#P00052>TGFbetareceptor I#P01278;TGF-beta signaling pathway#P00052>TGFbetareceptors#P01283;BMP/activin signaling pathway-drosophila#P06211>TGFbetaR I#P06241;TGF-beta signaling pathway#P00052>TGFbetareceptor II#P01277 CIOIN|Ensembl=ENSCING00000009503.3|UniProtKB=F6Y8H4 F6Y8H4 PTHR43655:SF2 ATP-DEPENDENT PROTEASE AFG3 LIKE MATRIX AAA PEPTIDASE SUBUNIT 2, ISOFORM A metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000007558.3|UniProtKB=F6T8A4 F6T8A4 PTHR16140:SF0 NON-STRUCTURAL MAINTENANCE OF CHROMOSOMES ELEMENT 4 NON-STRUCTURAL MAINTENANCE OF CHROMOSOMES ELEMENT 4 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;DNA damage response#GO:0006974;response to stress#GO:0006950;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular response to stress#GO:0033554;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;catalytic complex#GO:1902494;transferase complex#GO:1990234;condensed chromosome#GO:0000793;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000017920.1|UniProtKB=H2XQF1 H2XQF1 LOC104266244 PTHR46009:SF1 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN VTA1 HOMOLOG VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN VTA1 HOMOLOG localization#GO:0051179;endosomal transport#GO:0016197;cellular localization#GO:0051641;establishment of localization#GO:0051234;vacuolar transport#GO:0007034;transport#GO:0006810;endosome transport via multivesicular body sorting pathway#GO:0032509;late endosome to vacuole transport via multivesicular body sorting pathway#GO:0032511;late endosome to vacuole transport#GO:0045324;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;cellular process#GO:0009987;multivesicular body sorting pathway#GO:0071985 cytoplasm#GO:0005737;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cellular anatomical entity#GO:0110165;organelle#GO:0043226;late endosome#GO:0005770;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150 CIOIN|Ensembl=ENSCING00000004468.3|UniProtKB=F6U4H3 F6U4H3 PTHR43107:SF22 LONG-CHAIN FATTY ACID TRANSPORT PROTEIN VERY LONG-CHAIN ACYL-COA SYNTHETASE long-chain fatty acid-CoA ligase activity#GO:0004467;ligase activity#GO:0016874;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;ATP-dependent activity#GO:0140657;organic acid transmembrane transporter activity#GO:0005342;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877;monocarboxylic acid transmembrane transporter activity#GO:0008028;organic anion transmembrane transporter activity#GO:0008514;lipid transporter activity#GO:0005319;transporter activity#GO:0005215 long-chain fatty acid metabolic process#GO:0001676;oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;monocarboxylic acid transport#GO:0015718;macromolecule localization#GO:0033036;organic anion transport#GO:0015711;organic acid transport#GO:0015849;fatty acid transport#GO:0015908;transport#GO:0006810;carboxylic acid transport#GO:0046942;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;lipid transport#GO:0006869;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;localization#GO:0051179;organic substance transport#GO:0071702;fatty acid metabolic process#GO:0006631;establishment of localization#GO:0051234;lipid localization#GO:0010876;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;import into cell#GO:0098657;long-chain fatty acid transport#GO:0015909;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000011757.2|UniProtKB=F6TAA1 F6TAA1 LOC100125887 PTHR24044:SF417 NOTCH LIGAND FAMILY MEMBER WEARY, ISOFORM B protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 intercellular signal molecule#PC00207 CIOIN|Ensembl=ENSCING00000015232.2|UniProtKB=F6VBY8 F6VBY8 LOC100183814 PTHR11875:SF7 TESTIS-SPECIFIC Y-ENCODED PROTEIN AT14585P-RELATED protein binding#GO:0005515;protein-containing complex binding#GO:0044877;histone binding#GO:0042393;binding#GO:0005488;chromatin binding#GO:0003682 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;protein-DNA complex organization#GO:0071824;nucleosome organization#GO:0034728;nucleosome assembly#GO:0006334;protein-containing complex organization#GO:0043933;protein-containing complex assembly#GO:0065003;chromatin organization#GO:0006325;cellular component organization#GO:0016043;protein-DNA complex assembly#GO:0065004;chromatin remodeling#GO:0006338;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 CIOIN|Ensembl=ENSCING00000017701.2|UniProtKB=H2XT39 H2XT39 PTHR19960:SF11 TEKTIN TEKTIN cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cell projection organization#GO:0030030;microtubule-based movement#GO:0007018;cilium or flagellum-dependent cell motility#GO:0001539;cell motility#GO:0048870;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031;cilium movement involved in cell motility#GO:0060294;cilium movement#GO:0003341;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cilium-dependent cell motility#GO:0060285;microtubule-based process#GO:0007017;organelle organization#GO:0006996;plasma membrane bounded cell projection assembly#GO:0120031 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 CIOIN|Ensembl=ENSCING00000016316.2|UniProtKB=F6ZSB0 F6ZSB0 LOC100179329 PTHR10146:SF14 PROLINE SYNTHETASE CO-TRANSCRIBED BACTERIAL HOMOLOG PROTEIN PYRIDOXAL PHOSPHATE HOMEOSTASIS PROTEIN heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000024077.1|UniProtKB=H2XSD2 H2XSD2 PTHR13284:SF4 GH01354P C2H2-TYPE DOMAIN-CONTAINING PROTEIN nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159;ribonucleoprotein complex binding#GO:0043021;mRNA binding#GO:0003729;protein-containing complex binding#GO:0044877;mRNA 3'-UTR binding#GO:0003730 cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000016031.2|UniProtKB=F6Q4H4 F6Q4H4 LOC100182493 PTHR19969:SF19 SH2-SH3 ADAPTOR PROTEIN-RELATED SH2 DOMAIN-CONTAINING PROTEIN molecular adaptor activity#GO:0060090;signaling adaptor activity#GO:0035591;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;protein tyrosine kinase binding#GO:1990782;receptor tyrosine kinase binding#GO:0030971;signaling receptor binding#GO:0005102;kinase binding#GO:0019900 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cell motility#GO:0048870;cellular process#GO:0009987;cell migration#GO:0016477;signaling#GO:0023052 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000012422.2|UniProtKB=F6R8L5 F6R8L5 PTHR11102:SF147 SEL-1-LIKE PROTEIN SEL1L ADAPTOR SUBUNIT OF ERAD E3 UBIQUITIN LIGASE response to organic substance#GO:0010033;macromolecule catabolic process#GO:0009057;cellular response to stimulus#GO:0051716;response to endoplasmic reticulum stress#GO:0034976;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;response to organonitrogen compound#GO:0010243;ERAD pathway#GO:0036503;cellular process#GO:0009987;primary metabolic process#GO:0044238;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;cellular response to stress#GO:0033554;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000022437.1|UniProtKB=H2XWP1 H2XWP1 PTHR24064:SF577 SOLUTE CARRIER FAMILY 22 MEMBER GH09241P secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000000633.3|UniProtKB=F6RQS4 F6RQS4 LOC100177452 PTHR12604:SF2 KU AUTOANTIGEN DNA HELICASE X-RAY REPAIR CROSS-COMPLEMENTING PROTEIN 6 telomeric DNA binding#GO:0042162;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;double-strand break repair#GO:0006302;telomere organization#GO:0032200;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;telomere maintenance#GO:0000723;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;double-strand break repair via nonhomologous end joining#GO:0006303;nucleic acid metabolic process#GO:0090304;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;response to stress#GO:0006950;organelle organization#GO:0006996;chromosome organization#GO:0051276;nitrogen compound metabolic process#GO:0006807;cellular response to stress#GO:0033554;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259;metabolic process#GO:0008152 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA helicase#PC00011;DNA metabolism protein#PC00009 CIOIN|Ensembl=ENSCING00000009571.3|UniProtKB=F6TJQ3 F6TJQ3 PTHR10924:SF4 MAJOR FACILITATOR SUPERFAMILY PROTEIN-RELATED GH15861P tetrapyrrole binding#GO:0046906;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;binding#GO:0005488;organic cyclic compound binding#GO:0097159;heme binding#GO:0020037 localization#GO:0051179;organic substance transport#GO:0071702;metal ion transport#GO:0030001;establishment of localization#GO:0051234;transport#GO:0006810;monoatomic cation transport#GO:0006812;nitrogen compound transport#GO:0071705;iron ion transport#GO:0006826;transition metal ion transport#GO:0000041;monoatomic ion transport#GO:0006811 cellular anatomical entity#GO:0110165;membrane#GO:0016020 secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000022669.1|UniProtKB=H2XQ20 H2XQ20 PTHR15160:SF1 VON HIPPEL-LINDAU PROTEIN VON HIPPEL-LINDAU DISEASE TUMOR SUPPRESSOR ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 Hypoxia response via HIF activation#P00030>VHL#P00816 CIOIN|Ensembl=ENSCING00000002386.3|UniProtKB=F6QZE9 F6QZE9 LOC100175648 PTHR21250:SF0 PRE-RRNA-PROCESSING PROTEIN TSR2 HOMOLOG PRE-RRNA-PROCESSING PROTEIN TSR2 HOMOLOG cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;maturation of SSU-rRNA#GO:0030490;ribosomal small subunit biogenesis#GO:0042274;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000004101.3|UniProtKB=F6YGW9 F6YGW9 PTHR21245:SF15 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN RRM DOMAIN-CONTAINING PROTEIN nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000021650.1|UniProtKB=H2XT65 H2XT65 PTHR13847:SF150 SARCOSINE DEHYDROGENASE-RELATED OXIDOREDUCTASE TDA3-RELATED cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 dehydrogenase#PC00092;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000000577.3|UniProtKB=F6PYE4 F6PYE4 LOC100186896 PTHR23113:SF327 GUANINE NUCLEOTIDE EXCHANGE FACTOR EXCHANGE PROTEIN DIRECTLY ACTIVATED BY CAMP, ISOFORM E nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;small GTPase-mediated signal transduction#GO:0007264;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;Ras protein signal transduction#GO:0007265;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 CIOIN|Ensembl=ENSCING00000007217.3|UniProtKB=F6W713 F6W713 PTHR13036:SF0 BETA1,4 MANNOSYLTRANSFERASE CHITOBIOSYLDIPHOSPHODOLICHOL BETA-MANNOSYLTRANSFERASE mannosyltransferase activity#GO:0000030;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111 CIOIN|Ensembl=ENSCING00000020975.1|UniProtKB=H2XX60 H2XX60 PTHR13439:SF0 CT120 PROTEIN TOPOISOMERASE I DAMAGE AFFECTED PROTEIN 4 lipid homeostasis#GO:0055088;homeostatic process#GO:0042592;chemical homeostasis#GO:0048878 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000015965.2|UniProtKB=F6X3J8 F6X3J8 LOC100180402 PTHR14320:SF2 COILED-COIL DOMAIN-CONTAINING PROTEIN 181 COILED-COIL DOMAIN-CONTAINING PROTEIN 181 CIOIN|Ensembl=ENSCING00000005792.3|UniProtKB=F6RME1 F6RME1 PTHR28584:SF1 FAMILY WITH SEQUENCE SIMILARITY 228 MEMBER A PROTEIN FAM228B CIOIN|Ensembl=ENSCING00000023366.1|UniProtKB=H2Y012 H2Y012 PTHR24373:SF370 SLIT RELATED LEUCINE-RICH REPEAT NEURONAL PROTEIN FISH-LIPS, ISOFORM E external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 transmembrane signal receptor#PC00197 CIOIN|Ensembl=ENSCING00000002789.3|UniProtKB=F6ZYB8 F6ZYB8 PTHR10340:SF58 SPHINGOMYELIN PHOSPHODIESTERASE SPHINGOMYELIN PHOSPHODIESTERASE A phosphodiesterase#PC00185;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000006339.3|UniProtKB=F6QJY0 F6QJY0 PTHR24023:SF1096 COLLAGEN ALPHA COLLAGEN ALPHA-1(I) CHAIN-LIKE structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;external encapsulating structure organization#GO:0045229;extracellular matrix organization#GO:0030198 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;extracellular region#GO:0005576 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 CIOIN|Ensembl=ENSCING00000023337.1|UniProtKB=H2XM06 H2XM06 LOC100180170 PTHR44147:SF2 DEHYDROGENASE/REDUCTASE SDR FAMILY MEMBER 1 DEHYDROGENASE_REDUCTASE SDR FAMILY MEMBER 1 dehydrogenase#PC00092;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000008961.3|UniProtKB=F6Q5L9 F6Q5L9 PTHR24115:SF802 KINESIN-RELATED KINESIN-LIKE PROTEIN UNC-104 pyrophosphatase activity#GO:0016462;cytoskeletal protein binding#GO:0008092;microtubule motor activity#GO:0003777;tubulin binding#GO:0015631;ATP-dependent activity#GO:0140657;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;cytoskeletal motor activity#GO:0003774;microtubule binding#GO:0008017;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;ribonucleoside triphosphate phosphatase activity#GO:0017111;ATP hydrolysis activity#GO:0016887 vesicle transport along microtubule#GO:0047496;cellular localization#GO:0051641;organelle localization#GO:0051640;vesicle localization#GO:0051648;transport#GO:0006810;microtubule-based movement#GO:0007018;cellular process#GO:0009987;transport along microtubule#GO:0010970;localization#GO:0051179;microtubule-based transport#GO:0099111;establishment of localization#GO:0051234;microtubule-based process#GO:0007017;establishment of vesicle localization#GO:0051650;cytoskeleton-dependent intracellular transport#GO:0030705;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;organelle transport along microtubule#GO:0072384;establishment of organelle localization#GO:0051656;vesicle cytoskeletal trafficking#GO:0099518 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;microtubule associated complex#GO:0005875;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 CIOIN|Ensembl=ENSCING00000009013.3|UniProtKB=F6RCH7 F6RCH7 PTHR46803:SF2 E3 UBIQUITIN-PROTEIN LIGASE CHIP E3 UBIQUITIN-PROTEIN LIGASE CHIP transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;protein binding#GO:0005515;aminoacyltransferase activity#GO:0016755;protein-folding chaperone binding#GO:0051087;catalytic activity, acting on a protein#GO:0140096 positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of protein metabolic process#GO:0051246;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;protein catabolic process#GO:0030163;organonitrogen compound catabolic process#GO:1901565;protein modification process#GO:0036211;post-translational protein modification#GO:0043687;positive regulation of proteolysis#GO:0045862;modification-dependent macromolecule catabolic process#GO:0043632;regulation of biological process#GO:0050789;positive regulation of metabolic process#GO:0009893;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;protein polyubiquitination#GO:0000209;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;positive regulation of biological process#GO:0048518;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;response to organic substance#GO:0010033;regulation of proteolysis#GO:0030162;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;cellular response to stimulus#GO:0051716;protein quality control for misfolded or incompletely synthesized proteins#GO:0006515;cellular response to chemical stimulus#GO:0070887;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;cellular response to organic substance#GO:0071310;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;organonitrogen compound metabolic process#GO:1901564;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;cellular response to topologically incorrect protein#GO:0035967;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;response to stress#GO:0006950;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;response to topologically incorrect protein#GO:0035966;biological regulation#GO:0065007;cellular response to stress#GO:0033554;regulation of metabolic process#GO:0019222 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 Parkinson disease#P00049>CHIP#P01214 CIOIN|Ensembl=ENSCING00000009590.3|UniProtKB=F6SXM4 F6SXM4 LOC101242470 PTHR19375:SF144 HEAT SHOCK PROTEIN 70KDA ENDOPLASMIC RETICULUM CHAPERONE BIP signal transduction#GO:0007165;endoplasmic reticulum unfolded protein response#GO:0030968;protein catabolic process#GO:0030163;organonitrogen compound catabolic process#GO:1901565;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;response to unfolded protein#GO:0006986;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;protein metabolic process#GO:0019538;signaling#GO:0023052;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;response to organic substance#GO:0010033;macromolecule catabolic process#GO:0009057;cellular response to stimulus#GO:0051716;response to endoplasmic reticulum stress#GO:0034976;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;ERAD pathway#GO:0036503;cell communication#GO:0007154;response to organonitrogen compound#GO:0010243;cellular process#GO:0009987;cellular response to topologically incorrect protein#GO:0035967;primary metabolic process#GO:0044238;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;response to topologically incorrect protein#GO:0035966;cellular response to unfolded protein#GO:0034620;biological regulation#GO:0065007;cellular response to stress#GO:0033554 membrane-enclosed lumen#GO:0031974;endoplasmic reticulum protein-containing complex#GO:0140534;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endoplasmic reticulum lumen#GO:0005788;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783 Hsp70 family chaperone#PC00027 Parkinson disease#P00049>Hsp70#P01208;Apoptosis signaling pathway#P00006>HSP70#P00321 CIOIN|Ensembl=ENSCING00000007831.4|UniProtKB=F6UK82 F6UK82 PTHR11006:SF53 PROTEIN ARGININE N-METHYLTRANSFERASE PROTEIN ARGININE N-METHYLTRANSFERASE 3 N-methyltransferase activity#GO:0008170;histone modifying activity#GO:0140993;transferase activity#GO:0016740;catalytic activity#GO:0003824;histone methyltransferase activity#GO:0042054;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a protein#GO:0140096;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;protein methyltransferase activity#GO:0008276 protein-DNA complex organization#GO:0071824;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;cellular component organization#GO:0016043;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;methylation#GO:0032259;macromolecule methylation#GO:0043414;nitrogen compound metabolic process#GO:0006807;protein-containing complex organization#GO:0043933;chromatin organization#GO:0006325;protein metabolic process#GO:0019538;chromatin remodeling#GO:0006338;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000020956.1|UniProtKB=H2XV98 H2XV98 LOC100177737 PTHR12002:SF116 CLAUDIN CLAUDIN-11-LIKE cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cell-cell junction organization#GO:0045216;cellular component biogenesis#GO:0044085;cell-cell junction assembly#GO:0007043;cell junction organization#GO:0034330;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;cell adhesion#GO:0007155;cellular process#GO:0009987 tight junction#GO:0070160;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cell junction#GO:0030054;bicellular tight junction#GO:0005923;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;apical junction complex#GO:0043296;plasma membrane#GO:0005886 cell junction protein#PC00070;tight junction#PC00214 CIOIN|Ensembl=ENSCING00000024693.1|UniProtKB=H2XKP2 H2XKP2 PTHR13342:SF2 RAGULATOR COMPLEX PROTEIN LAMTOR5 RAGULATOR COMPLEX PROTEIN LAMTOR5 nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;cellular response to nitrogen compound#GO:1901699;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;positive regulation of TOR signaling#GO:0032008;regulation of signal transduction#GO:0009966;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;positive regulation of TORC1 signaling#GO:1904263;cellular response to stimulus#GO:0051716;regulation of TORC1 signaling#GO:1903432;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;response to organonitrogen compound#GO:0010243;cellular process#GO:0009987;regulation of TOR signaling#GO:0032006;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cellular response to organonitrogen compound#GO:0071417;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;vacuolar membrane#GO:0005774;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;lytic vacuole#GO:0000323;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;lysosome#GO:0005764;membrane-bounded organelle#GO:0043227;guanyl-nucleotide exchange factor complex#GO:0032045 CIOIN|Ensembl=ENSCING00000006529.3|UniProtKB=F6PH23 F6PH23 PTHR16213:SF78 SELENOPROTEIN N SELENOPROTEIN N skeletal muscle organ development#GO:0060538;inorganic ion homeostasis#GO:0098771;cellular developmental process#GO:0048869;muscle organ development#GO:0007517;muscle cell differentiation#GO:0042692;calcium ion homeostasis#GO:0055074;animal organ development#GO:0048513;developmental process#GO:0032502;homeostatic process#GO:0042592;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;cellular process#GO:0009987;tissue development#GO:0009888;muscle tissue development#GO:0060537;monoatomic ion homeostasis#GO:0050801;muscle cell development#GO:0055001;cell development#GO:0048468;muscle structure development#GO:0061061;cell differentiation#GO:0030154;striated muscle cell differentiation#GO:0051146;anatomical structure development#GO:0048856;skeletal muscle tissue development#GO:0007519 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000002772.2|UniProtKB=F7AGU6 F7AGU6 LOC100186452 PTHR19960:SF25 TEKTIN TEKTIN-1 cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cell projection organization#GO:0030030;microtubule-based movement#GO:0007018;cilium or flagellum-dependent cell motility#GO:0001539;cell motility#GO:0048870;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031;cilium movement involved in cell motility#GO:0060294;cilium movement#GO:0003341;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cilium-dependent cell motility#GO:0060285;microtubule-based process#GO:0007017;organelle organization#GO:0006996;plasma membrane bounded cell projection assembly#GO:0120031 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 CIOIN|Ensembl=ENSCING00000003448.3|UniProtKB=F6WY01 F6WY01 PTHR13258:SF0 SYNDETIN SYNDETIN protein binding#GO:0005515;binding#GO:0005488;SNARE binding#GO:0000149 localization#GO:0051179;endosomal transport#GO:0016197;localization within membrane#GO:0051668;cellular localization#GO:0051641;vesicle-mediated transport to the plasma membrane#GO:0098876;endocytic recycling#GO:0032456;establishment of localization#GO:0051234;transport#GO:0006810;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;cellular process#GO:0009987 cytoplasm#GO:0005737;endosome#GO:0005768;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular vesicle#GO:0097708;recycling endosome#GO:0055037;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000014754.2|UniProtKB=F6W940 F6W940 PTHR44305:SF24 SI:DKEY-192D15.2-RELATED TYROSINE-PROTEIN KINASE C03B1.5-RELATED CIOIN|Ensembl=ENSCING00000005519.3|UniProtKB=F6YP78 F6YP78 PTHR11785:SF512 AMINO ACID TRANSPORTER SOBREMESA, ISOFORM B L-amino acid transmembrane transporter activity#GO:0015179;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;amino acid transmembrane transporter activity#GO:0015171;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215;organic acid transmembrane transporter activity#GO:0005342 localization#GO:0051179;organic substance transport#GO:0071702;amino acid transmembrane transport#GO:0003333;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;amino acid transport#GO:0006865;organic anion transport#GO:0015711;organic acid transport#GO:0015849;transport#GO:0006810;nitrogen compound transport#GO:0071705;organic acid transmembrane transport#GO:1903825;carboxylic acid transport#GO:0046942;cellular process#GO:0009987;carboxylic acid transmembrane transport#GO:1905039 transporter#PC00227 CIOIN|Ensembl=ENSCING00000005863.3|UniProtKB=F6UGC2 F6UGC2 PTHR14222:SF1 CONDENSIN CONDENSIN-2 COMPLEX SUBUNIT D3 protein binding#GO:0005515;histone binding#GO:0042393;binding#GO:0005488 nuclear chromosome segregation#GO:0098813;sister chromatid segregation#GO:0000819;meiotic cell cycle#GO:0051321;nuclear division#GO:0000280;cell cycle process#GO:0022402;chromosome condensation#GO:0030261;cellular component organization#GO:0016043;cellular process#GO:0009987;mitotic cell cycle process#GO:1903047;mitotic chromosome condensation#GO:0007076;chromosome segregation#GO:0007059;cellular component organization or biogenesis#GO:0071840;chromosome organization involved in meiotic cell cycle#GO:0070192;mitotic cell cycle#GO:0000278;reproduction#GO:0000003;organelle organization#GO:0006996;chromosome organization#GO:0051276;meiotic cell cycle process#GO:1903046;sexual reproduction#GO:0019953;reproductive process#GO:0022414;cell cycle#GO:0007049;mitotic nuclear division#GO:0140014;organelle fission#GO:0048285;mitotic sister chromatid segregation#GO:0000070 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;condensed chromosome, centromeric region#GO:0000779;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;chromosomal region#GO:0098687;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 CIOIN|Ensembl=ENSCING00000009008.3|UniProtKB=F6PHE6 F6PHE6 PTHR10019:SF5 SNF5 SWI_SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY B MEMBER 1 molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;protein-macromolecule adaptor activity#GO:0030674 protein-DNA complex organization#GO:0071824;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;cellular component organization#GO:0016043;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;protein-containing complex organization#GO:0043933;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;chromatin remodeling#GO:0006338;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA metabolism protein#PC00009 Wnt signaling pathway#P00057>SWI/SNF#P01435 CIOIN|Ensembl=ENSCING00000017652.2|UniProtKB=F6WZ37 F6WZ37 PTHR19970:SF0 RIBOSOMAL PROTEIN L39E LARGE RIBOSOMAL SUBUNIT PROTEIN EL39 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic large ribosomal subunit#GO:0022625;large ribosomal subunit#GO:0015934;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000001615.3|UniProtKB=F6RZA6 F6RZA6 LOC100184368 PTHR44329:SF57 SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED INTEGRIN-LINKED PROTEIN KINASE transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cell-matrix adhesion#GO:0007160;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;integrin-mediated signaling pathway#GO:0007229;substrate adhesion-dependent cell spreading#GO:0034446;cell communication#GO:0007154;cell adhesion#GO:0007155;cell-substrate adhesion#GO:0031589;cellular process#GO:0009987;signaling#GO:0023052 intracellular non-membrane-bounded organelle#GO:0043232;actomyosin#GO:0042641;stress fiber#GO:0001725;non-membrane-bounded organelle#GO:0043228;actin filament bundle#GO:0032432;actin cytoskeleton#GO:0015629;anchoring junction#GO:0070161;focal adhesion#GO:0005925;cell junction#GO:0030054;cell-substrate junction#GO:0030055;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Integrin signalling pathway#P00034>ILK#P00935 CIOIN|Ensembl=ENSCING00000002073.3|UniProtKB=F7AA31 F7AA31 PTHR24061:SF422 CALCIUM-SENSING RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTORS FAMILY 3 PROFILE DOMAIN-CONTAINING PROTEIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 CIOIN|Ensembl=ENSCING00000000395.3|UniProtKB=F6SEM6 F6SEM6 PTHR46367:SF1 ATAXIN-7-LIKE PROTEIN 3 ATAXIN-7-LIKE PROTEIN 3 transcription coactivator activity#GO:0003713;molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;protein-macromolecule adaptor activity#GO:0030674 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of RNA metabolic process#GO:0051254;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 SAGA-type complex#GO:0070461;peptidase complex#GO:1905368;histone acetyltransferase complex#GO:0000123;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;acetyltransferase complex#GO:1902493;chromatin#GO:0000785;protein-DNA complex#GO:0032993;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein acetyltransferase complex#GO:0031248;protein-containing complex#GO:0032991;chromosome#GO:0005694;SAGA complex#GO:0000124;membrane-bounded organelle#GO:0043227;DUBm complex#GO:0071819;nuclear protein-containing complex#GO:0140513 CIOIN|Ensembl=ENSCING00000003673.3|UniProtKB=F7ADC2 F7ADC2 LOC100181489 PTHR10219:SF43 GLYCOLIPID TRANSFER PROTEIN-RELATED GLYCOLIPID TRANSFER PROTEIN DOMAIN-CONTAINING PROTEIN lipid transfer activity#GO:0120013;small molecule binding#GO:0036094;binding#GO:0005488;amide binding#GO:0033218;phospholipid transporter activity#GO:0005548;lipid binding#GO:0008289;ion binding#GO:0043167;anion binding#GO:0043168;phospholipid binding#GO:0005543;transporter activity#GO:0005215;lipid transporter activity#GO:0005319 amide transport#GO:0042886;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;membrane organization#GO:0061024;transport#GO:0006810;nitrogen compound transport#GO:0071705;cellular component organization#GO:0016043;lipid localization#GO:0010876;intermembrane lipid transfer#GO:0120009;cellular process#GO:0009987;lipid transport#GO:0006869 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;membrane#GO:0016020;intracellular anatomical structure#GO:0005622 transfer/carrier protein#PC00219 CIOIN|Ensembl=ENSCING00000024379.1|UniProtKB=H2XYP9 H2XYP9 PTHR24393:SF15 ZINC FINGER PROTEIN IP01243P-RELATED DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 CIOIN|Ensembl=ENSCING00000000904.3|UniProtKB=F6U1B1 F6U1B1 PTHR11958:SF99 SODIUM/DICARBOXYLATE SYMPORTER-RELATED SODIUM-DEPENDENT EXCITATORY AMINO ACID TRANSPORTER GLT-6-RELATED inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;organic acid:sodium symporter activity#GO:0005343;organic acid transmembrane transporter activity#GO:0005342;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;L-amino acid transmembrane transporter activity#GO:0015179;organic anion transmembrane transporter activity#GO:0008514;monoatomic cation transmembrane transporter activity#GO:0008324;acidic amino acid transmembrane transporter activity#GO:0015172;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;amino acid:sodium symporter activity#GO:0005283;secondary active transmembrane transporter activity#GO:0015291;L-glutamate transmembrane transporter activity#GO:0005313;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;metal ion transmembrane transporter activity#GO:0046873;active monoatomic ion transmembrane transporter activity#GO:0022853;amino acid transmembrane transporter activity#GO:0015171;inorganic cation transmembrane transporter activity#GO:0022890;neutral L-amino acid transmembrane transporter activity#GO:0015175;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294 L-amino acid transport#GO:0015807;transmembrane transport#GO:0055085;dicarboxylic acid transport#GO:0006835;organic anion transport#GO:0015711;acidic amino acid transport#GO:0015800;amino acid transport#GO:0006865;organic acid transport#GO:0015849;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942;cellular process#GO:0009987;carboxylic acid transmembrane transport#GO:1905039;localization#GO:0051179;organic substance transport#GO:0071702;amino acid transmembrane transport#GO:0003333;establishment of localization#GO:0051234;L-alpha-amino acid transmembrane transport#GO:1902475;organic acid transmembrane transport#GO:1903825 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 primary active transporter#PC00068;transporter#PC00227 CIOIN|Ensembl=ENSCING00000013620.2|UniProtKB=F6V1C0 F6V1C0 LOC100184460 PTHR10173:SF52 METHIONINE SULFOXIDE REDUCTASE METHIONINE-R-SULFOXIDE REDUCTASE B1 oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 reductase#PC00198;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000008741.3|UniProtKB=F6TMD1 F6TMD1 PTHR12486:SF4 APRATAXIN-RELATED APRATAXIN hydrolase activity, acting on ester bonds#GO:0016788;nucleic acid binding#GO:0003676;DNA exonuclease activity, producing 5'-phosphomonoesters#GO:0016895;nuclease activity#GO:0004518;DNA exonuclease activity#GO:0004529;5'-3' exonuclease activity#GO:0008409;binding#GO:0005488;catalytic activity#GO:0003824;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters#GO:0016796;single-stranded DNA binding#GO:0003697;damaged DNA binding#GO:0003684;catalytic activity, acting on a nucleic acid#GO:0140640;double-stranded DNA binding#GO:0003690;exonuclease activity#GO:0004527;RNA binding#GO:0003723;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;hydrolase activity#GO:0016787;DNA nuclease activity#GO:0004536;catalytic activity, acting on DNA#GO:0140097;double-stranded RNA binding#GO:0003725 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;DNA damage response#GO:0006974;response to stress#GO:0006950;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular response to stress#GO:0033554;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 damaged DNA-binding protein#PC00086;DNA metabolism protein#PC00009 CIOIN|Ensembl=ENSCING00000007419.3|UniProtKB=F7B882 F7B882 PTHR11475:SF121 OXIDASE/PEROXIDASE THYROID PEROXIDASE-LIKE oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;antioxidant activity#GO:0016209;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 peroxidase#PC00180;oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000007193.3|UniProtKB=F6YRY7 F6YRY7 LOC100176493 PTHR23389:SF21 CHROMOSOME TRANSMISSION FIDELITY FACTOR 18 ATPASE FAMILY AAA DOMAIN-CONTAINING PROTEIN 5 nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA metabolism protein#PC00009 CIOIN|Ensembl=ENSCING00000003538.3|UniProtKB=Q4H3P2 Q4H3P2 Ci-DUSP8.16 PTHR10159:SF533 DUAL SPECIFICITY PROTEIN PHOSPHATASE TYROSINE-PROTEIN PHOSPHATASE VHP-1 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;protein tyrosine phosphatase activity#GO:0004725;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 regulation of MAPK cascade#GO:0043408;negative regulation of biological process#GO:0048519;peptidyl-tyrosine dephosphorylation#GO:0035335;macromolecule modification#GO:0043412;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;protein modification process#GO:0036211;regulation of intracellular signal transduction#GO:1902531;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;negative regulation of MAPK cascade#GO:0043409;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of cell communication#GO:0010646;negative regulation of response to stimulus#GO:0048585;macromolecule metabolic process#GO:0043170;negative regulation of signaling#GO:0023057;cellular metabolic process#GO:0044237;protein dephosphorylation#GO:0006470;organonitrogen compound metabolic process#GO:1901564;cellular process#GO:0009987;primary metabolic process#GO:0044238;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;dephosphorylation#GO:0016311;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 protein phosphatase#PC00195;protein modifying enzyme#PC00260 Oxidative stress response#P00046>MKP5#P01131 CIOIN|Ensembl=ENSCING00000006999.3|UniProtKB=F6SAU0 F6SAU0 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE SSU-1 sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824 cellular metabolic process#GO:0044237;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000004746.3|UniProtKB=F6PRK2 F6PRK2 nf-x-like PTHR12360:SF12 NUCLEAR TRANSCRIPTION FACTOR, X-BOX BINDING 1 NFX1 TRANSCRIPTIONAL REPRESSOR NF-X1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 zinc finger transcription factor#PC00244 CIOIN|Ensembl=ENSCING00000005514.3|UniProtKB=F6YPI9 F6YPI9 PTHR11616:SF289 SODIUM/CHLORIDE DEPENDENT TRANSPORTER TRANSPORTER secondary active monocarboxylate transmembrane transporter activity#GO:0015355;inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;organic acid:sodium symporter activity#GO:0005343;organic acid transmembrane transporter activity#GO:0005342;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;chloride transmembrane transporter activity#GO:0015108;organic anion transmembrane transporter activity#GO:0008514;monoatomic cation transmembrane transporter activity#GO:0008324;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;amino acid:sodium symporter activity#GO:0005283;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;metal ion transmembrane transporter activity#GO:0046873;active monoatomic ion transmembrane transporter activity#GO:0022853;monoatomic anion transmembrane transporter activity#GO:0008509;monocarboxylic acid transmembrane transporter activity#GO:0008028;amino acid transmembrane transporter activity#GO:0015171;inorganic anion transmembrane transporter activity#GO:0015103;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;organic anion transport#GO:0015711;amino acid transport#GO:0006865;organic acid transport#GO:0015849;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;localization#GO:0051179;organic substance transport#GO:0071702;sodium ion transport#GO:0006814;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;sodium ion transmembrane transport#GO:0035725 cell projection#GO:0042995;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 primary active transporter#PC00068;transporter#PC00227 CIOIN|Ensembl=ENSCING00000014965.2|UniProtKB=F6UWC7 F6UWC7 LOC100186735 PTHR10671:SF108 EPITHELIAL MEMBRANE PROTEIN-RELATED CLAUDIN FAMILY PROTEIN-RELATED cytoskeletal protein#PC00085 CIOIN|Ensembl=ENSCING00000003677.3|UniProtKB=F6ZV03 F6ZV03 PTHR12385:SF96 CHOLINE TRANSPORTER-LIKE (SLC FAMILY 44) CHOLINE TRANSPORTER-LIKE PROTEIN transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 localization#GO:0051179;establishment of localization#GO:0051234;cellular process#GO:0009987;transmembrane transport#GO:0055085;transport#GO:0006810 cellular anatomical entity#GO:0110165;membrane#GO:0016020 secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000004880.3|UniProtKB=F6SP32 F6SP32 LOC100180728 PTHR19865:SF0 U3 SMALL NUCLEOLAR RNA INTERACTING PROTEIN 2 U3 SMALL NUCLEOLAR RNA-INTERACTING PROTEIN 2 snoRNA binding#GO:0030515;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 small-subunit processome#GO:0032040;ribonucleoprotein complex#GO:1990904;preribosome#GO:0030684;protein-containing complex#GO:0032991 CIOIN|Ensembl=ENSCING00000012229.2|UniProtKB=F6ZNW9 F6ZNW9 LOC100175831 PTHR24300:SF397 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 2U1 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;tetrapyrrole binding#GO:0046906;steroid hydroxylase activity#GO:0008395;oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497;heme binding#GO:0020037 response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;response to chemical#GO:0042221;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 oxygenase#PC00177;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000008173.3|UniProtKB=F6UQ68 F6UQ68 PTHR46242:SF1 ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 9 ZCCHC9 ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 9 intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000009945.3|UniProtKB=F6R5M7 F6R5M7 LOC100181286 PTHR12480:SF41 ARGININE DEMETHYLASE AND LYSYL-HYDROXYLASE JMJD JMJC DOMAIN-CONTAINING PROTEIN sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;dioxygenase activity#GO:0051213;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity#GO:0016491 positive regulation of gene expression#GO:0010628;positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of protein metabolic process#GO:0051246;regulation of amide metabolic process#GO:0034248;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;protein modification process#GO:0036211;regulation of cellular component organization#GO:0051128;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;protein hydroxylation#GO:0018126;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;positive regulation of biological process#GO:0048518;positive regulation of translation#GO:0045727;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;regulation of protein-containing complex disassembly#GO:0043244;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;positive regulation of protein metabolic process#GO:0051247;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;post-transcriptional regulation of gene expression#GO:0010608;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;regulation of translation#GO:0006417;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000010987.3|UniProtKB=F7AYH7 F7AYH7 LOC100180437 PTHR12242:SF1 OS02G0130600 PROTEIN-RELATED MYND-TYPE DOMAIN-CONTAINING PROTEIN cellular anatomical entity#GO:0110165;membrane#GO:0016020 CIOIN|Ensembl=ENSCING00000001800.3|UniProtKB=F6X5P6 F6X5P6 LOC108949611 PTHR21183:SF18 RIBOSOMAL PROTEIN L47, MITOCHONDRIAL-RELATED LARGE RIBOSOMAL SUBUNIT PROTEIN UL29M structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;mitochondrial gene expression#GO:0140053;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;mitochondrial translation#GO:0032543;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;mitochondrial large ribosomal subunit#GO:0005762;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;mitochondrial ribosome#GO:0005761;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;ribosomal subunit#GO:0044391;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;organellar ribosome#GO:0000313;protein-containing complex#GO:0032991;large ribosomal subunit#GO:0015934;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;ribosome#GO:0005840;mitochondrial protein-containing complex#GO:0098798 ribosomal protein#PC00202;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000003986.3|UniProtKB=F6VAS2 F6VAS2 LOC100186064 PTHR45619:SF12 SERINE/THREONINE-PROTEIN PHOSPHATASE PP2A-RELATED SERINE_THREONINE-PROTEIN PHOSPHATASE 2A CATALYTIC SUBUNIT ALPHA ISOFORM hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;protein serine/threonine phosphatase activity#GO:0004722;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 cell cycle#GO:0007049;mitotic cell cycle#GO:0000278;cellular process#GO:0009987 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 protein phosphatase#PC00195;protein modifying enzyme#PC00260 p53 pathway#P00059>PP2A#P04630;Wnt signaling pathway#P00057>PP2A#P01438;p53 pathway feedback loops 2#P04398>PP2A-C#P04659;p53 pathway by glucose deprivation#P04397>PP2A-C#P04643;FGF signaling pathway#P00021>PP2A#P00629;EGF receptor signaling pathway#P00018>PP2A#P00547 CIOIN|Ensembl=ENSCING00000021069.1|UniProtKB=H2XLC2 H2XLC2 PTHR11134:SF3 ADAPTOR COMPLEX SUBUNIT BETA FAMILY MEMBER AP COMPLEX SUBUNIT BETA localization#GO:0051179;vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234;cellular process#GO:0009987;transport#GO:0006810 membrane traffic protein#PC00150 CIOIN|Ensembl=ENSCING00000004167.3|UniProtKB=F7BPM3 F7BPM3 PTHR23322:SF1 FAS-ASSOCIATED PROTEIN FAS-ASSOCIATED FACTOR 2 protein binding#GO:0005515;ubiquitin-like protein binding#GO:0032182;binding#GO:0005488;ubiquitin binding#GO:0043130 response to organic substance#GO:0010033;macromolecule catabolic process#GO:0009057;cellular response to stimulus#GO:0051716;response to endoplasmic reticulum stress#GO:0034976;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;response to organonitrogen compound#GO:0010243;ERAD pathway#GO:0036503;cellular process#GO:0009987;primary metabolic process#GO:0044238;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;cellular response to stress#GO:0033554;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000021036.1|UniProtKB=H2Y2K5 H2Y2K5 PTHR13710:SF105 DNA HELICASE RECQ FAMILY MEMBER ATP-DEPENDENT DNA HELICASE Q1 ATP-dependent activity, acting on DNA#GO:0008094;3'-5' DNA helicase activity#GO:0043138;helicase activity#GO:0004386;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;DNA helicase activity#GO:0003678;catalytic activity, acting on DNA#GO:0140097 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;DNA geometric change#GO:0032392;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;DNA conformation change#GO:0071103;nucleic acid metabolic process#GO:0090304;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;response to stress#GO:0006950;organelle organization#GO:0006996;chromosome organization#GO:0051276;nitrogen compound metabolic process#GO:0006807;DNA duplex unwinding#GO:0032508;cellular response to stress#GO:0033554;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259;metabolic process#GO:0008152 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;chromosome#GO:0005694;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA helicase#PC00011;DNA metabolism protein#PC00009 CIOIN|Ensembl=ENSCING00000019961.1|UniProtKB=H2XSE0 H2XSE0 PTHR14002:SF20 ENDOGLIN/TGF-BETA RECEPTOR TYPE III ZONA PELLUCIDA-LIKE DOMAIN-CONTAINING PROTEIN 1 transmembrane signal receptor#PC00197 CIOIN|Ensembl=ENSCING00000021414.1|UniProtKB=H2XJJ4 H2XJJ4 LOC100187458 PTHR35269:SF1 SMALL VCP/P97-INTERACTING PROTEIN SMALL VCP_P97-INTERACTING PROTEIN negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;regulation of catabolic process#GO:0009894;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of protein catabolic process#GO:0042177;positive regulation of cellular metabolic process#GO:0031325;positive regulation of cellular catabolic process#GO:0031331;regulation of localization#GO:0032879;regulation of cellular component organization#GO:0051128;regulation of protein catabolic process#GO:0042176;regulation of proteolysis involved in protein catabolic process#GO:1903050;regulation of biological process#GO:0050789;negative regulation of proteasomal protein catabolic process#GO:1901799;regulation of cellular response to stress#GO:0080135;regulation of transport#GO:0051049;positive regulation of metabolic process#GO:0009893;regulation of protein-containing complex assembly#GO:0043254;regulation of cellular component biogenesis#GO:0044087;negative regulation of cellular component organization#GO:0051129;regulation of protein transport#GO:0051223;positive regulation of biological process#GO:0048518;negative regulation of cellular process#GO:0048523;regulation of protein localization#GO:0032880;regulation of proteolysis#GO:0030162;negative regulation of response to stimulus#GO:0048585;regulation of response to endoplasmic reticulum stress#GO:1905897;regulation of autophagy#GO:0010506;regulation of response to stress#GO:0080134;negative regulation of metabolic process#GO:0009892;negative regulation of transport#GO:0051051;negative regulation of protein metabolic process#GO:0051248;negative regulation of proteolysis#GO:0045861;regulation of cellular catabolic process#GO:0031329;regulation of cellular localization#GO:0060341;negative regulation of nitrogen compound metabolic process#GO:0051172;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of proteasomal protein catabolic process#GO:0061136;regulation of response to stimulus#GO:0048583;negative regulation of catabolic process#GO:0009895;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;positive regulation of catabolic process#GO:0009896;negative regulation of protein-containing complex assembly#GO:0031333;positive regulation of autophagy#GO:0010508;negative regulation of proteolysis involved in protein catabolic process#GO:1903051;regulation of metabolic process#GO:0019222;regulation of establishment of protein localization#GO:0070201;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;endoplasmic reticulum membrane#GO:0005789 CIOIN|Ensembl=ENSCING00000012624.2|UniProtKB=F6ZDT9 F6ZDT9 LOC100178859 PTHR23050:SF485 CALCIUM BINDING PROTEIN RE52086P cation binding#GO:0043169;small molecule binding#GO:0036094;molecular function regulator activity#GO:0098772;binding#GO:0005488;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;enzyme regulator activity#GO:0030234 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 calmodulin-related#PC00061 CIOIN|Ensembl=ENSCING00000013369.2|UniProtKB=F6YE69 F6YE69 PTHR33963:SF2 MKRN2 OPPOSITE STRAND PROTEIN MKRN2 OPPOSITE STRAND PROTEIN CIOIN|Ensembl=ENSCING00000013359.2|UniProtKB=F6YWN9 F6YWN9 PTHR12322:SF53 DOUBLESEX AND MAB-3 RELATED TRANSCRIPTION FACTOR DMRT DOUBLESEX-MAB RELATED 11E sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;sex differentiation#GO:0007548;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;developmental process involved in reproduction#GO:0003006;regulation of primary metabolic process#GO:0080090;reproduction#GO:0000003;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;reproductive process#GO:0022414;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218 CIOIN|Ensembl=ENSCING00000021762.1|UniProtKB=H2XUG5 H2XUG5 PTHR10192:SF5 MOLYBDOPTERIN BIOSYNTHESIS PROTEIN GEPHYRIN transferase activity#GO:0016740;catalytic activity#GO:0003824 heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;organophosphate biosynthetic process#GO:0090407;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;organophosphate metabolic process#GO:0019637;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000004808.3|UniProtKB=A0A1W5BAI1 A0A1W5BAI1 LOC100187409 PTHR14557:SF5 PROTEIN C7ORF21 UBIQUITIN-LIKE DOMAIN-CONTAINING PROTEIN response to organic substance#GO:0010033;macromolecule catabolic process#GO:0009057;cellular response to stimulus#GO:0051716;response to endoplasmic reticulum stress#GO:0034976;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;response to organonitrogen compound#GO:0010243;ERAD pathway#GO:0036503;cellular process#GO:0009987;primary metabolic process#GO:0044238;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;cellular response to stress#GO:0033554;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 CIOIN|Ensembl=ENSCING00000010816.3|UniProtKB=F6WXL3 F6WXL3 PTHR24412:SF497 KELCH PROTEIN KELCH-LIKE PROTEIN 18 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000006063.3|UniProtKB=F6ZGT0 F6ZGT0 LOC100175773 PTHR14221:SF0 WD REPEAT DOMAIN 44 WD REPEAT-CONTAINING PROTEIN 44 CIOIN|Ensembl=ENSCING00000006823.3|UniProtKB=F7B0A1 F7B0A1 PTHR24039:SF58 FIBRILLIN-RELATED EGF-LIKE DOMAIN-CONTAINING PROTEIN extracellular matrix structural protein#PC00103 CIOIN|Ensembl=ENSCING00000002422.3|UniProtKB=F7B4M1 F7B4M1 PTHR11309:SF99 FRIZZLED FRIZZLED-4 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;protein binding#GO:0005515;Wnt-protein binding#GO:0017147;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;non-canonical Wnt signaling pathway#GO:0035567;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;cell-cell signaling by wnt#GO:0198738;canonical Wnt signaling pathway#GO:0060070;cell-cell signaling#GO:0007267;signaling#GO:0023052;Wnt signaling pathway#GO:0016055 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;extracellular space#GO:0005615;membrane#GO:0016020;extracellular region#GO:0005576;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Wnt signaling pathway#P00057>Frizzled#P01428;Cadherin signaling pathway#P00012>Frizzled#P00475 CIOIN|Ensembl=ENSCING00000014230|UniProtKB=F6Y089 F6Y089 PTHR11067:SF9 INOSINE TRIPHOSPHATE PYROPHOSPHATASE/HAM1 PROTEIN INOSINE TRIPHOSPHATE PYROPHOSPHATASE pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;nucleoside triphosphate metabolic process#GO:0009141;heterocycle metabolic process#GO:0046483;nucleoside phosphate catabolic process#GO:1901292;heterocycle catabolic process#GO:0046700;nucleoside triphosphate catabolic process#GO:0009143;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate catabolic process#GO:0046434;phosphate-containing compound metabolic process#GO:0006796;cellular nitrogen compound catabolic process#GO:0044270;aromatic compound catabolic process#GO:0019439;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;organic cyclic compound catabolic process#GO:1901361;catabolic process#GO:0009056;organophosphate metabolic process#GO:0019637;organic substance catabolic process#GO:1901575;nucleobase-containing compound catabolic process#GO:0034655;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248;nucleobase-containing small molecule metabolic process#GO:0055086 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 nucleotide phosphatase#PC00173 Thiamin metabolism#P02780>Nucleoside triphosphatase#P03180 CIOIN|Ensembl=ENSCING00000008568.3|UniProtKB=F6X0T1 F6X0T1 LOC100177232 PTHR14309:SF10 EXPRESSED PROTEIN PH DOMAIN-CONTAINING PROTEIN biological regulation#GO:0065007;regulation of biological process#GO:0050789;regulation of cell differentiation#GO:0045595;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794 cellular anatomical entity#GO:0110165;membrane#GO:0016020 CIOIN|Ensembl=ENSCING00000019378.1|UniProtKB=H2XY22 H2XY22 LOC100187443 PTHR24320:SF226 RETINOL DEHYDROGENASE RETINOL DEHYDROGENASE 11 dehydrogenase#PC00092;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000008395.3|UniProtKB=F6XR12 F6XR12 LOC100175965 PTHR11229:SF8 50S RIBOSOMAL PROTEIN L3 LARGE RIBOSOMAL SUBUNIT PROTEIN UL3M structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;mitochondrial large ribosomal subunit#GO:0005762;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;mitochondrial ribosome#GO:0005761;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;ribosomal subunit#GO:0044391;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;organellar ribosome#GO:0000313;protein-containing complex#GO:0032991;large ribosomal subunit#GO:0015934;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;ribosome#GO:0005840;mitochondrial protein-containing complex#GO:0098798 ribosomal protein#PC00202;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000007069.3|UniProtKB=F6WW70 F6WW70 PTHR46173:SF1 CCA TRNA NUCLEOTIDYLTRANSFERASE 1, MITOCHONDRIAL CCA TRNA NUCLEOTIDYLTRANSFERASE 1, MITOCHONDRIAL tRNA binding#GO:0000049;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;tRNA metabolic process#GO:0006399;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 RNA processing factor#PC00147;RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000014984.2|UniProtKB=F6VM24 F6VM24 LOC100186787 PTHR10036:SF3 CD59 GLYCOPROTEIN PROTEIN SLEEPLESS-RELATED CIOIN|Ensembl=ENSCING00000020428.1|UniProtKB=H2XKU1 H2XKU1 PTHR15344:SF12 CDC42 EFFECTOR PROTEIN BORG CRIB DOMAIN-CONTAINING PROTEIN enzyme binding#GO:0019899;protein binding#GO:0005515;small GTPase binding#GO:0031267;binding#GO:0005488 positive regulation of organelle organization#GO:0010638;regulation of plasma membrane bounded cell projection assembly#GO:0120032;regulation of anatomical structure morphogenesis#GO:0022603;regulation of cellular component organization#GO:0051128;regulation of actin polymerization or depolymerization#GO:0008064;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;regulation of protein-containing complex assembly#GO:0043254;regulation of cell shape#GO:0008360;regulation of biological quality#GO:0065008;regulation of cellular component biogenesis#GO:0044087;regulation of actin cytoskeleton organization#GO:0032956;regulation of actin filament-based process#GO:0032970;positive regulation of cellular component biogenesis#GO:0044089;regulation of protein polymerization#GO:0032271;positive regulation of biological process#GO:0048518;regulation of anatomical structure size#GO:0090066;regulation of actin filament length#GO:0030832;regulation of organelle organization#GO:0033043;regulation of actin filament organization#GO:0110053;cellular component organization#GO:0016043;regulation of plasma membrane bounded cell projection organization#GO:0120035;cellular process#GO:0009987;positive regulation of protein polymerization#GO:0032273;regulation of actin filament polymerization#GO:0030833;regulation of cellular component size#GO:0032535;positive regulation of cellular process#GO:0048522;regulation of supramolecular fiber organization#GO:1902903;cellular component organization or biogenesis#GO:0071840;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;regulation of cell projection assembly#GO:0060491;regulation of cell projection organization#GO:0031344;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;membrane#GO:0016020;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000024246.1|UniProtKB=H2XSY0 H2XSY0 PTHR10283:SF82 SOLUTE CARRIER FAMILY 13 MEMBER SOLUTE CARRIER FAMILY 13 MEMBER 2 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 localization#GO:0051179;establishment of localization#GO:0051234;cellular process#GO:0009987;transmembrane transport#GO:0055085;transport#GO:0006810 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000006324.3|UniProtKB=F6Q3L6 F6Q3L6 PTHR12621:SF7 CYSTEINE AND HISTIDINE-RICH DOMAIN CHORD -CONTAINING PROTEIN CYSTEINE AND HISTIDINE-RICH DOMAIN-CONTAINING PROTEIN 1 cation binding#GO:0043169;metal ion binding#GO:0046872;ion binding#GO:0043167;small molecule binding#GO:0036094;zinc ion binding#GO:0008270;binding#GO:0005488;transition metal ion binding#GO:0046914 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000007943.3|UniProtKB=F6ZRC6 F6ZRC6 PTHR11732:SF506 ALDO/KETO REDUCTASE ALDO-KETO REDUCTASE 1B, ISOFORM C-RELATED oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 reductase#PC00198;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000002029.3|UniProtKB=F6W615 F6W615 PTHR32026:SF10 METHYLTRANSFERASE-LIKE PROTEIN 24 METHYLTRANSFERASE-LIKE PROTEIN 24-RELATED methyltransferase#PC00155 CIOIN|Ensembl=ENSCING00000010654.3|UniProtKB=F6SD85 F6SD85 yb1_2_3 PTHR11544:SF60 COLD SHOCK DOMAIN CONTAINING PROTEINS LD37574P nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159 regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of biosynthetic process#GO:0009889;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 CIOIN|Ensembl=ENSCING00000006086.3|UniProtKB=F6YXK7 F6YXK7 LOC100185458 PTHR11886:SF35 DYNEIN LIGHT CHAIN DYNEIN LIGHT CHAIN protein binding#GO:0005515;binding#GO:0005488 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;microtubule cytoskeleton#GO:0015630;dynein complex#GO:0030286;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic dynein complex#GO:0005868;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;microtubule or microtubule-binding cytoskeletal protein#PC00157 Huntington disease#P00029>Dynein complex#P00774 CIOIN|Ensembl=ENSCING00000002015.3|UniProtKB=F6WSS9 F6WSS9 LOC100181975 PTHR46458:SF1 BLR2807 PROTEIN GEO09476P1 transporter#PC00227 CIOIN|Ensembl=ENSCING00000008944.3|UniProtKB=F7A786 F7A786 LOC100179531 PTHR23248:SF63 PHOSPHOLIPID SCRAMBLASE-RELATED PHOSPHOLIPID SCRAMBLASE phospholipid transporter activity#GO:0005548;transporter activity#GO:0005215;lipid transporter activity#GO:0005319 organophosphate ester transport#GO:0015748;macromolecule localization#GO:0033036;membrane organization#GO:0061024;plasma membrane organization#GO:0007009;transport#GO:0006810;plasma membrane phospholipid scrambling#GO:0017121;endomembrane system organization#GO:0010256;cellular component organization#GO:0016043;regulation of membrane lipid distribution#GO:0097035;phospholipid transport#GO:0015914;cellular process#GO:0009987;lipid transport#GO:0006869;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;biological regulation#GO:0065007;lipid translocation#GO:0034204;lipid localization#GO:0010876;phospholipid translocation#GO:0045332 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transporter#PC00227 CIOIN|Ensembl=ENSCING00000015927.2|UniProtKB=F6XTD6 F6XTD6 PTHR12381:SF56 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN U FAMILY MEMBER B30.2_SPRY DOMAIN-CONTAINING PROTEIN-RELATED nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;alternative mRNA splicing, via spliceosome#GO:0000380;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000006330.3|UniProtKB=F6PY05 F6PY05 PTHR36978:SF4 P-LOOP CONTAINING NUCLEOTIDE TRIPHOSPHATE HYDROLASE P-LOOP CONTAINING NUCLEOSIDE TRIPHOSPHATE HYDROLASE PROTEIN metabolite interconversion enzyme#PC00262;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000014946.2|UniProtKB=F6VKK3 F6VKK3 LOC100180662 PTHR22761:SF5 CHARGED MULTIVESICULAR BODY PROTEIN CHARGED MULTIVESICULAR BODY PROTEIN 6 endosomal transport#GO:0016197;cellular localization#GO:0051641;membrane organization#GO:0061024;vacuolar transport#GO:0007034;transport#GO:0006810;late endosome to vacuole transport via multivesicular body sorting pathway#GO:0032511;vesicle-mediated transport#GO:0016192;late endosome to vacuole transport#GO:0045324;cellular component organization#GO:0016043;cellular process#GO:0009987;multivesicular body sorting pathway#GO:0071985;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;vesicle budding from membrane#GO:0006900;establishment of localization#GO:0051234;organelle organization#GO:0006996;endosome transport via multivesicular body sorting pathway#GO:0032509;establishment of localization in cell#GO:0051649;vesicle organization#GO:0016050;intracellular transport#GO:0046907 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endosome membrane#GO:0010008;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle membrane#GO:0030659;late endosome#GO:0005770 membrane traffic protein#PC00150 CIOIN|Ensembl=ENSCING00000004105.3|UniProtKB=Q4H383 Q4H383 Ci-MAPKK1_2 PTHR48013:SF31 DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 5-RELATED DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE DSOR1 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;MAPK cascade#GO:0000165;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;cellular process#GO:0009987;signaling#GO:0023052 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 EGF receptor signaling pathway#P00018>MEK1-2#P00559;Endothelin signaling pathway#P00019>MEK#P00572;FGF signaling pathway#P00021>MEK1-2#P00642;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>MEK#P00891;PDGF signaling pathway#P00047>MEK#P01162 CIOIN|Ensembl=ENSCING00000014372.2|UniProtKB=F7AG43 F7AG43 LOC100178177 PTHR45715:SF6 ATPASE H+-TRANSPORTING V1 SUBUNIT E1A-RELATED V-TYPE PROTON ATPASE SUBUNIT E inorganic molecular entity transmembrane transporter activity#GO:0015318;transmembrane transporter activity#GO:0022857;primary active transmembrane transporter activity#GO:0015399;ATP-dependent activity#GO:0140657;proton transmembrane transporter activity#GO:0015078;active monoatomic ion transmembrane transporter activity#GO:0022853;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;ATPase-coupled transmembrane transporter activity#GO:0042626;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;active transmembrane transporter activity#GO:0022804;monoatomic ion transmembrane transporter activity#GO:0015075;inorganic cation transmembrane transporter activity#GO:0022890 CIOIN|Ensembl=ENSCING00000009451.3|UniProtKB=A0A1W3JFF0 A0A1W3JFF0 gla1 PTHR24416:SF564 TYROSINE-PROTEIN KINASE RECEPTOR MACROPHAGE-STIMULATING PROTEIN RECEPTOR signaling receptor activity#GO:0038023;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;molecular transducer activity#GO:0060089;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672;transmembrane signaling receptor activity#GO:0004888 signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;positive regulation of cellular metabolic process#GO:0031325;developmental process#GO:0032502;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;nervous system development#GO:0007399;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;system development#GO:0048731;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;regulation of molecular function#GO:0065009;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;positive regulation of phosphorylation#GO:0042327;cellular response to stimulus#GO:0051716;positive regulation of catalytic activity#GO:0043085;multicellular organism development#GO:0007275;positive regulation of phosphorus metabolic process#GO:0010562;cell communication#GO:0007154;cell motility#GO:0048870;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphate metabolic process#GO:0045937;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;multicellular organismal process#GO:0032501;cell migration#GO:0016477;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 receptor complex#GO:0043235;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 CIOIN|Ensembl=ENSCING00000015951.2|UniProtKB=F6X4K3 F6X4K3 PTHR20371:SF1 ENOLASE-PHOSPHATASE E1 ENOLASE-PHOSPHATASE E1 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;proteinogenic amino acid metabolic process#GO:0170039;sulfur compound metabolic process#GO:0006790;proteinogenic amino acid biosynthetic process#GO:0170038;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;aspartate family amino acid biosynthetic process#GO:0009067;alpha-amino acid biosynthetic process#GO:1901607;nitrogen compound metabolic process#GO:0006807;amino acid biosynthetic process#GO:0008652;alpha-amino acid metabolic process#GO:1901605;aspartate family amino acid metabolic process#GO:0009066;small molecule biosynthetic process#GO:0044283;L-amino acid biosynthetic process#GO:0170034;carboxylic acid metabolic process#GO:0019752;L-amino acid metabolic process#GO:0170033;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 phosphatase#PC00181;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000006665.3|UniProtKB=F6TD21 F6TD21 PTHR14340:SF9 MICROFIBRIL-ASSOCIATED GLYCOPROTEIN 3 FIBRONECTIN TYPE-III DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000020310.1|UniProtKB=H2XYW0 H2XYW0 PTHR10540:SF7 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT F-RELATED 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 7 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 endopeptidase complex#GO:1905369;proteasome complex#GO:0000502;peptidase complex#GO:1905368;intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;catalytic complex#GO:1902494 translation initiation factor#PC00224;translation factor#PC00223 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489;Cell cycle#P00013>Proteasome#P00480 CIOIN|Ensembl=ENSCING00000014306.2|UniProtKB=F6UAF0 F6UAF0 LOC101242267 PTHR11071:SF561 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE D-RELATED peptidyl-prolyl cis-trans isomerase activity#GO:0003755;isomerase activity#GO:0016853;catalytic activity, acting on a protein#GO:0140096;binding#GO:0005488;catalytic activity#GO:0003824;peptide binding#GO:0042277;amide binding#GO:0033218 macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein peptidyl-prolyl isomerization#GO:0000413;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein folding#GO:0006457;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 chaperone#PC00072 CIOIN|Ensembl=ENSCING00000006311.3|UniProtKB=F6RJV3 F6RJV3 PTHR43153:SF1 ELECTRON TRANSFER FLAVOPROTEIN ALPHA ELECTRON TRANSFER FLAVOPROTEIN SUBUNIT ALPHA, MITOCHONDRIAL nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;flavin adenine dinucleotide binding#GO:0050660;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167 oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;lipid oxidation#GO:0034440;cellular metabolic process#GO:0044237;lipid catabolic process#GO:0016042;lipid modification#GO:0030258;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;fatty acid catabolic process#GO:0009062;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;fatty acid metabolic process#GO:0006631;small molecule catabolic process#GO:0044282;fatty acid beta-oxidation#GO:0006635;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;cellular lipid metabolic process#GO:0044255;cellular lipid catabolic process#GO:0044242;carboxylic acid metabolic process#GO:0019752;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;monocarboxylic acid catabolic process#GO:0072329 oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000008277.3|UniProtKB=F6QHN7 F6QHN7 LOC100180789 PTHR11767:SF102 INWARD RECTIFIER POTASSIUM CHANNEL INWARDLY RECTIFYING POTASSIUM CHANNEL 1, ISOFORM F monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated potassium channel activity#GO:0005249;channel activity#GO:0015267;transporter activity#GO:0005215;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;ligand-gated monoatomic cation channel activity#GO:0099094;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;ligand-gated channel activity#GO:0022834 regulation of monoatomic ion transmembrane transport#GO:0034765;regulation of transmembrane transport#GO:0034762;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;regulation of localization#GO:0032879;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;localization#GO:0051179;regulation of biological process#GO:0050789;import across plasma membrane#GO:0098739;regulation of transport#GO:0051049;establishment of localization#GO:0051234;regulation of cellular process#GO:0050794;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;monoatomic cation transport#GO:0006812;regulation of monoatomic ion transport#GO:0043269;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;import into cell#GO:0098657;potassium ion transport#GO:0006813;potassium ion import across plasma membrane#GO:1990573 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 CIOIN|Ensembl=ENSCING00000007515.3|UniProtKB=F6UJL9 F6UJL9 PTHR10161:SF14 TARTRATE-RESISTANT ACID PHOSPHATASE TYPE 5 TARTRATE-RESISTANT ACID PHOSPHATASE TYPE 5 hydrolase#PC00121;phosphatase#PC00181 CIOIN|Ensembl=ENSCING00000010025.3|UniProtKB=H2Y2D4 H2Y2D4 PTHR34349:SF1 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 32 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 32 phosphatase binding#GO:0019902;enzyme binding#GO:0019899;protein binding#GO:0005515;binding#GO:0005488 protein-binding activity modulator#PC00095;phosphatase modulator#PC00184 CIOIN|Ensembl=ENSCING00000007543.2|UniProtKB=F6T957 F6T957 PTHR10648:SF4 SERINE/THREONINE-PROTEIN PHOSPHATASE PP2A 65 KDA REGULATORY SUBUNIT PROTEIN PHOSPHATASE 2 (FORMERLY 2A), REGULATORY SUBUNIT A, BETA ISOFORM-RELATED phosphatase regulator activity#GO:0019208;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;protein phosphatase regulator activity#GO:0019888 macromolecule modification#GO:0043412;nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;dephosphorylation#GO:0016311;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein dephosphorylation#GO:0006470;cellular metabolic process#GO:0044237;protein metabolic process#GO:0019538;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;protein serine/threonine phosphatase complex#GO:0008287;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 phosphatase modulator#PC00184 FGF signaling pathway#P00021>PP2A#P00629 CIOIN|Ensembl=ENSCING00000004050.3|UniProtKB=F6RWR9 F6RWR9 PTHR23189:SF102 RNA RECOGNITION MOTIF-CONTAINING FI21126P1-RELATED membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000023671.1|UniProtKB=H2XRA5 H2XRA5 PTHR24373:SF398 SLIT RELATED LEUCINE-RICH REPEAT NEURONAL PROTEIN LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 6 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 transmembrane signal receptor#PC00197 CIOIN|Ensembl=ENSCING00000001869.3|UniProtKB=F6SJF0 F6SJF0 LOC100186307 PTHR11082:SF31 TRNA-DIHYDROURIDINE SYNTHASE TRNA-DIHYDROURIDINE(20A_20B) SYNTHASE [NAD(P)+]-LIKE catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on RNA#GO:0140098;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor#GO:0016628 RNA processing factor#PC00147 CIOIN|Ensembl=ENSCING00000023793.1|UniProtKB=H2Y3B6 H2Y3B6 PTHR11576:SF22 ZONA PELLUCIDA SPERM-BINDING PROTEIN 3 ONCOPROTEIN INDUCED TRANSCRIPT 3 CIOIN|Ensembl=ENSCING00000015922.2|UniProtKB=F6YZ79 F6YZ79 PTHR23407:SF1 ATPASE INHIBITOR/5-FORMYLTETRAHYDROFOLATE CYCLO-LIGASE 5-FORMYLTETRAHYDROFOLATE CYCLO-LIGASE ligase activity#GO:0016874;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;folic acid-containing compound metabolic process#GO:0006760;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;heterocycle biosynthetic process#GO:0018130;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular modified amino acid metabolic process#GO:0006575;cellular nitrogen compound biosynthetic process#GO:0044271;aromatic compound biosynthetic process#GO:0019438;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 ligase#PC00142;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000018776.1|UniProtKB=H2XPS0 H2XPS0 PTHR22802:SF379 C-TYPE LECTIN SUPERFAMILY MEMBER CHONDROITIN SULFATE PROTEOGLYCAN 2 ISOFORM X1 membrane traffic protein#PC00150 CIOIN|Ensembl=ENSCING00000012817.2|UniProtKB=F6W3Q9 F6W3Q9 LOC100179350 PTHR43157:SF31 PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN-RELATED PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000010144.3|UniProtKB=F6PI58 F6PI58 PTHR31094:SF2 RIKEN CDNA 2310061I04 GENE RIKEN CDNA 2310061I04 GENE CIOIN|Ensembl=ENSCING00000006055.3|UniProtKB=F6ZZC3 F6ZZC3 PTHR13604:SF0 DC12-RELATED ABASIC SITE PROCESSING PROTEIN HMCES CIOIN|Ensembl=ENSCING00000012299.2|UniProtKB=A0A1W5BC53 A0A1W5BC53 PTHR16146:SF46 INTELECTIN INTELECTIN-1A-RELATED CIOIN|Ensembl=ENSCING00000015022.2|UniProtKB=F6U734 F6U734 PTHR10117:SF54 TRANSIENT RECEPTOR POTENTIAL CHANNEL TRANSIENT RECEPTOR POTENTIAL-GAMMA PROTEIN calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;calcium channel activity#GO:0005262;small molecule binding#GO:0036094;binding#GO:0005488;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;anion binding#GO:0043168;ion binding#GO:0043167;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;alcohol binding#GO:0043178 inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;calcium ion transmembrane transport#GO:0070588;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;homeostatic process#GO:0042592;monoatomic cation homeostasis#GO:0055080;inorganic ion transmembrane transport#GO:0098660;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;cellular process#GO:0009987;regulation of cytosolic calcium ion concentration#GO:0051480;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;calcium ion transport#GO:0006816;monoatomic ion homeostasis#GO:0050801;localization#GO:0051179;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation transport#GO:0006812;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;cation channel complex#GO:0034703;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 Alzheimer disease-presenilin pathway#P00004>Capacitative calcium channels#P00124 CIOIN|Ensembl=ENSCING00000004658.3|UniProtKB=F6RHA1 F6RHA1 LOC100177411 PTHR11093:SF2 RUVB-RELATED REPTIN AND PONTIN RUVB-LIKE 2 ATP-dependent activity, acting on DNA#GO:0008094;catalytic activity, acting on a nucleic acid#GO:0140640;DNA helicase activity#GO:0003678;catalytic activity, acting on DNA#GO:0140097;helicase activity#GO:0004386;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;protein-DNA complex organization#GO:0071824;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;protein-RNA complex assembly#GO:0022618;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;protein-containing complex organization#GO:0043933;regulation of biosynthetic process#GO:0009889;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;ribonucleoprotein complex biogenesis#GO:0022613;biological regulation#GO:0065007;chromatin organization#GO:0006325;protein-RNA complex organization#GO:0071826;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;chromatin remodeling#GO:0006338;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 Ino80 complex#GO:0031011;histone acetyltransferase complex#GO:0000123;acetyltransferase complex#GO:1902493;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;NuA4 histone acetyltransferase complex#GO:0035267;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;non-membrane-bounded organelle#GO:0043228;chromosome#GO:0005694;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;protein-DNA complex#GO:0032993;transferase complex#GO:1990234;INO80-type complex#GO:0097346;intracellular organelle lumen#GO:0070013;ATPase complex#GO:1904949;SWI/SNF superfamily-type complex#GO:0070603;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;protein acetyltransferase complex#GO:0031248;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;histone deacetylase complex#GO:0000118;nuclear lumen#GO:0031981;Swr1 complex#GO:0000812;nuclear protein-containing complex#GO:0140513 CIOIN|Ensembl=ENSCING00000013207.2|UniProtKB=F6VSN5 F6VSN5 PTHR24034:SF195 EGF-LIKE DOMAIN-CONTAINING PROTEIN EGF-LIKE DOMAIN-CONTAINING PROTEIN extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 CIOIN|Ensembl=ENSCING00000022006.1|UniProtKB=H2XXX5 H2XXX5 PTHR18945:SF924 NEUROTRANSMITTER GATED ION CHANNEL NEURONAL ACETYLCHOLINE RECEPTOR SUBUNIT BETA-4-LIKE ISOFORM X1 transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;signaling receptor activity#GO:0038023;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;neurotransmitter receptor activity#GO:0030594;ligand-gated monoatomic ion channel activity#GO:0015276;transporter activity#GO:0005215;channel activity#GO:0015267;transmembrane signaling receptor activity#GO:0004888;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;molecular transducer activity#GO:0060089;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;ligand-gated channel activity#GO:0022834 response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;transmembrane transport#GO:0055085;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;membrane depolarization#GO:0051899;transport#GO:0006810;regulation of membrane potential#GO:0042391;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to nitrogen compound#GO:1901699;localization#GO:0051179;regulation of biological process#GO:0050789;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;cellular response to oxygen-containing compound#GO:1901701;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;synaptic signaling#GO:0099536;monoatomic ion transport#GO:0006811;signaling#GO:0023052;cell-cell signaling#GO:0007267;acetylcholine receptor signaling pathway#GO:0095500 membrane protein complex#GO:0098796;synapse#GO:0045202;plasma membrane signaling receptor complex#GO:0098802;transporter complex#GO:1990351;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;receptor complex#GO:0043235;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;neuron projection#GO:0043005;transmembrane transporter complex#GO:1902495;cell projection#GO:0042995;plasma membrane#GO:0005886 ligand-gated ion channel#PC00141;ion channel#PC00133;transporter#PC00227 CIOIN|Ensembl=ENSCING00000020677.1|UniProtKB=H2XJI9 H2XJI9 PTHR46064:SF1 QUEUINE TRNA-RIBOSYLTRANSFERASE ACCESSORY SUBUNIT 2 QUEUINE TRNA-RIBOSYLTRANSFERASE ACCESSORY SUBUNIT 2 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;tRNA metabolic process#GO:0006399;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;RNA modification#GO:0009451;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;tRNA modification#GO:0006400;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 RNA processing factor#PC00147;RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000007409.3|UniProtKB=F6RYU3 F6RYU3 PTHR43313:SF36 SHORT-CHAIN DEHYDROGENASE/REDUCTASE FAMILY 9C D-BETA-HYDROXYBUTYRATE DEHYDROGENASE, MITOCHONDRIAL catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 lipid metabolic process#GO:0006629;steroid metabolic process#GO:0008202;organic cyclic compound metabolic process#GO:1901360;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;primary metabolic process#GO:0044238 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000005406.3|UniProtKB=Q4H356 Q4H356 Ci-Neuralized-a PTHR12429:SF6 NEURALIZED PROTEIN NEURALIZED transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000021110.1|UniProtKB=A0A1W5B7N8 A0A1W5B7N8 LOC100183764 PTHR11699:SF302 ALDEHYDE DEHYDROGENASE-RELATED ALDEHYDE DEHYDROGENASE 2-RELATED oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 dehydrogenase#PC00092;oxidoreductase#PC00176 5-Hydroxytryptamine degredation#P04372>Aldehyde Dehydrogenase#P04402 CIOIN|Ensembl=ENSCING00000001074.3|UniProtKB=F7B0M6 F7B0M6 LOC100180029 PTHR45710:SF26 C-TYPE LECTIN DOMAIN-CONTAINING PROTEIN 180 RH26557P defense/immunity protein#PC00090 CIOIN|Ensembl=ENSCING00000007444.3|UniProtKB=F6SNN1 F6SNN1 LOC100184979 PTHR22806:SF0 NUCLEOPORIN NUP37 P37 -RELATED NUCLEOPORIN NUP37 envelope#GO:0031975;nuclear pore#GO:0005643;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;organelle envelope#GO:0031967;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transporter#PC00227 CIOIN|Ensembl=ENSCING00000021531.1|UniProtKB=H2XTN5 H2XTN5 LOC100182802 PTHR22747:SF18 NUCLEOPLASMIN GEO09167P1-RELATED chaperone#PC00072 CIOIN|Ensembl=ENSCING00000005133.3|UniProtKB=F6VBD5 F6VBD5 PTHR15071:SF17 MANNOSE-6-PHOSPHATE RECEPTOR FAMILY MEMBER CATION-INDEPENDENT MANNOSE-6-PHOSPHATE RECEPTOR growth factor binding#GO:0019838;protein binding#GO:0005515;binding#GO:0005488 localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;vacuolar transport#GO:0007034;transport#GO:0006810;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;cellular process#GO:0009987;lysosomal transport#GO:0007041 trans-Golgi network#GO:0005802;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;organelle subcompartment#GO:0031984;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791;late endosome#GO:0005770;plasma membrane#GO:0005886 membrane traffic protein#PC00150 Apoptosis signaling pathway#P00006>IGFR2#P00282;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>INSR IGF-R IRR#P00895;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>INSR IGF-R IRR#P00885 CIOIN|Ensembl=ENSCING00000024319.1|UniProtKB=H2Y360 H2Y360 PTHR10502:SF233 ANNEXIN ANNEXIN B9 lipid binding#GO:0008289;phospholipid binding#GO:0005543;binding#GO:0005488;phosphatidylserine binding#GO:0001786 localization#GO:0051179;endosomal transport#GO:0016197;cellular localization#GO:0051641;establishment of localization#GO:0051234;transport#GO:0006810;endosome transport via multivesicular body sorting pathway#GO:0032509;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;cellular process#GO:0009987;multivesicular body sorting pathway#GO:0071985 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;vesicle membrane#GO:0012506;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 calcium-binding protein#PC00060 CIOIN|Ensembl=ENSCING00000023276.1|UniProtKB=H2XWV9 H2XWV9 PTHR31609:SF1 YDJC DEACETYLASE FAMILY MEMBER CARBOHYDRATE DEACETYLASE hydrolase activity#GO:0016787;deacetylase activity#GO:0019213;catalytic activity#GO:0003824 CIOIN|Ensembl=ENSCING00000000994.3|UniProtKB=F6YLB5 F6YLB5 PTHR24064:SF577 SOLUTE CARRIER FAMILY 22 MEMBER GH09241P secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000000893.3|UniProtKB=F6U1L2 F6U1L2 PTHR43884:SF12 ACYL-COA DEHYDROGENASE ISOVALERYL-COA DEHYDROGENASE, MITOCHONDRIAL-RELATED oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 dehydrogenase#PC00092;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000006229.3|UniProtKB=F6YVT2 F6YVT2 LOC100178391 PTHR24229:SF112 NEUROPEPTIDES RECEPTOR CHEMOKINE-LIKE RECEPTOR 1 neuropeptide binding#GO:0042923;signaling receptor activity#GO:0038023;binding#GO:0005488;peptide binding#GO:0042277;amide binding#GO:0033218;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;neuropeptide signaling pathway#GO:0007218;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;neuron projection#GO:0043005;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 CIOIN|Ensembl=ENSCING00000023884.1|UniProtKB=H2XX77 H2XX77 PTHR12962:SF1 CALCIUM-REGULATED HEAT STABLE PROTEIN CRHSP-24-RELATED COLD SHOCK DOMAIN-CONTAINING PROTEIN CG9705 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159;mRNA 3'-UTR binding#GO:0003730 regulation of mRNA stability#GO:0043488;regulation of catabolic process#GO:0009894;regulation of mRNA catabolic process#GO:0061013;regulation of nitrogen compound metabolic process#GO:0051171;regulation of cellular catabolic process#GO:0031329;regulation of RNA stability#GO:0043487;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of biological quality#GO:0065008;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;post-transcriptional regulation of gene expression#GO:0010608;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000002475.3|UniProtKB=F7B4I8 F7B4I8 LOC100178927 PTHR15031:SF4 CARTILAGE INTERMEDIATE LAYER PROTEIN CLIP CARTILAGE INTERMEDIATE LAYER PROTEIN 1 CIOIN|Ensembl=ENSCING00000002054.3|UniProtKB=F7BDH1 F7BDH1 PTHR23030:SF39 PCD6 INTERACTING PROTEIN-RELATED PROGRAMMED CELL DEATH 6-INTERACTING PROTEIN endosomal transport#GO:0016197;cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;protein catabolic process#GO:0030163;late endosome to vacuole transport via multivesicular body sorting pathway#GO:0032511;nitrogen compound transport#GO:0071705;organonitrogen compound catabolic process#GO:1901565;late endosome to vacuole transport#GO:0045324;protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043328;establishment of protein localization#GO:0045184;ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043162;modification-dependent macromolecule catabolic process#GO:0043632;organic substance transport#GO:0071702;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;protein localization to organelle#GO:0033365;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;establishment of protein localization to vacuole#GO:0072666;modification-dependent protein catabolic process#GO:0019941;vacuolar transport#GO:0007034;macromolecule metabolic process#GO:0043170;protein localization to vacuole#GO:0072665;organonitrogen compound metabolic process#GO:1901564;establishment of protein localization to organelle#GO:0072594;vesicle-mediated transport#GO:0016192;multivesicular body sorting pathway#GO:0071985;cellular process#GO:0009987;protein localization#GO:0008104;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;localization#GO:0051179;cellular macromolecule localization#GO:0070727;protein transport#GO:0015031;endosome transport via multivesicular body sorting pathway#GO:0032509;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 cytoplasm#GO:0005737;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular vesicle#GO:0097708;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150 CIOIN|Ensembl=ENSCING00000014241.2|UniProtKB=F6XBI2 F6XBI2 PTHR19282:SF519 TETRASPANIN TETRASPANIN cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000024454.1|UniProtKB=H2XYA3 H2XYA3 PTHR31281:SF3 PROTEIN FAM219A PROTEIN FAM219A CIOIN|Ensembl=ENSCING00000014933.2|UniProtKB=F6Y6X7 F6Y6X7 PTHR11721:SF3 60S RIBOSOMAL PROTEIN L27A LARGE RIBOSOMAL SUBUNIT PROTEIN UL15 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic large ribosomal subunit#GO:0022625;large ribosomal subunit#GO:0015934;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000002676.3|UniProtKB=F6XQ09 F6XQ09 LOC100186582 PTHR17583:SF0 PHOSPHOINOSITIDE 3-KINASE REGULATORY SUBUNIT 4 PHOSPHOINOSITIDE 3-KINASE REGULATORY SUBUNIT 4 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular localization#GO:0051641;establishment of protein localization to vacuole#GO:0072666;macroautophagy#GO:0016236;macromolecule localization#GO:0033036;protein targeting to vacuole#GO:0006623;vacuolar transport#GO:0007034;transport#GO:0006810;protein localization to vacuole#GO:0072665;protein targeting#GO:0006605;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;late endosome to vacuole transport#GO:0045324;establishment of protein localization to organelle#GO:0072594;cellular metabolic process#GO:0044237;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;process utilizing autophagic mechanism#GO:0061919;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein transport#GO:0015031;catabolic process#GO:0009056;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;protein localization to organelle#GO:0033365;autophagy#GO:0006914;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 membrane protein complex#GO:0098796;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;phosphatidylinositol 3-kinase complex#GO:0005942;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;organelle#GO:0043226;organelle membrane contact site#GO:0044232;phosphatidylinositol 3-kinase complex, class III#GO:0035032;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695;extrinsic component of membrane#GO:0019898;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;late endosome#GO:0005770 kinase modulator#PC00140 CIOIN|Ensembl=ENSCING00000007173.3|UniProtKB=F6ZAY7 F6ZAY7 PTHR10270:SF317 SOX TRANSCRIPTION FACTOR TRANSCRIPTION FACTOR SOX-15-RELATED DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;cell differentiation#GO:0030154;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA metabolic process#GO:0051252;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;positive regulation of RNA metabolic process#GO:0051254;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;HMG box transcription factor#PC00024 CIOIN|Ensembl=ENSCING00000009852.3|UniProtKB=F6XG93 F6XG93 PTHR24055:SF561 MITOGEN-ACTIVATED PROTEIN KINASE MITOGEN-ACTIVATED PROTEIN KINASE 7 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;signaling#GO:0023052 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 CCKR signaling map#P06959>MAPK7#P07021;EGF receptor signaling pathway#P00018>ERK1-2#P00543;Interleukin signaling pathway#P00036>ERK#P00965;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>MAPK#P00835;PDGF signaling pathway#P00047>ERK#P01143;FGF signaling pathway#P00021>ERK1-2#P00627;Interferon-gamma signaling pathway#P00035>Serine kinase#P00955;Alzheimer disease-amyloid secretase pathway#P00003>MAPK#P00099;Apoptosis signaling pathway#P00006>MAPK#P00269;TGF-beta signaling pathway#P00052>p42/p44MAPKs#P01293;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>ERK#P00889;Parkinson disease#P00049>ERK#P01211;Endothelin signaling pathway#P00019>ERK#P00566 CIOIN|Ensembl=ENSCING00000014875.2|UniProtKB=F6ZA54 F6ZA54 PTHR24229:SF112 NEUROPEPTIDES RECEPTOR CHEMOKINE-LIKE RECEPTOR 1 neuropeptide binding#GO:0042923;signaling receptor activity#GO:0038023;binding#GO:0005488;peptide binding#GO:0042277;amide binding#GO:0033218;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;neuropeptide signaling pathway#GO:0007218;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;neuron projection#GO:0043005;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 CIOIN|Ensembl=ENSCING00000023786.1|UniProtKB=H2XKE1 H2XKE1 LOC113475062 PTHR13491:SF0 ZCCHC10 PROTEIN ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 10 CIOIN|Ensembl=ENSCING00000000123.3|UniProtKB=F6SIE8 F6SIE8 LOC100177748 PTHR11616:SF289 SODIUM/CHLORIDE DEPENDENT TRANSPORTER TRANSPORTER secondary active monocarboxylate transmembrane transporter activity#GO:0015355;inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;organic acid:sodium symporter activity#GO:0005343;organic acid transmembrane transporter activity#GO:0005342;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;chloride transmembrane transporter activity#GO:0015108;organic anion transmembrane transporter activity#GO:0008514;monoatomic cation transmembrane transporter activity#GO:0008324;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;amino acid:sodium symporter activity#GO:0005283;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;metal ion transmembrane transporter activity#GO:0046873;active monoatomic ion transmembrane transporter activity#GO:0022853;monoatomic anion transmembrane transporter activity#GO:0008509;monocarboxylic acid transmembrane transporter activity#GO:0008028;amino acid transmembrane transporter activity#GO:0015171;inorganic anion transmembrane transporter activity#GO:0015103;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;organic anion transport#GO:0015711;amino acid transport#GO:0006865;organic acid transport#GO:0015849;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;localization#GO:0051179;organic substance transport#GO:0071702;sodium ion transport#GO:0006814;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;sodium ion transmembrane transport#GO:0035725 cell projection#GO:0042995;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 primary active transporter#PC00068;transporter#PC00227 CIOIN|Ensembl=ENSCING00000007853.3|UniProtKB=F6W5P6 F6W5P6 PTHR11699:SF211 ALDEHYDE DEHYDROGENASE-RELATED ALDEHYDE DEHYDROGENASE FAMILY 16 MEMBER A1 dehydrogenase#PC00092;oxidoreductase#PC00176 5-Hydroxytryptamine degredation#P04372>Aldehyde Dehydrogenase#P04402;Ornithine degradation#P02758>Aminobutyraldehyde dehydrogenase#P03055;Phenylethylamine degradation#P02766>Phenylacetaldehyde dehydrogenase#P03102 CIOIN|Ensembl=ENSCING00000003129.3|UniProtKB=A0A1W5BQH4 A0A1W5BQH4 LOC100185594 PTHR47500:SF3 EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN EF-HAND DOMAIN-CONTAINING PROTEIN calmodulin-related#PC00061 CIOIN|Ensembl=ENSCING00000014160.2|UniProtKB=H2XWF3 H2XWF3 PTHR11360:SF318 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER 12 localization#GO:0051179;organic substance transport#GO:0071702;monocarboxylic acid transport#GO:0015718;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;organic anion transport#GO:0015711;organic acid transport#GO:0015849;transport#GO:0006810;nitrogen compound transport#GO:0071705;organic acid transmembrane transport#GO:1903825;carboxylic acid transport#GO:0046942;cellular process#GO:0009987;carboxylic acid transmembrane transport#GO:1905039 transporter#PC00227 CIOIN|Ensembl=ENSCING00000000132.3|UniProtKB=F7A0S5 F7A0S5 LOC100185032 PTHR23248:SF63 PHOSPHOLIPID SCRAMBLASE-RELATED PHOSPHOLIPID SCRAMBLASE phospholipid transporter activity#GO:0005548;transporter activity#GO:0005215;lipid transporter activity#GO:0005319 organophosphate ester transport#GO:0015748;macromolecule localization#GO:0033036;membrane organization#GO:0061024;plasma membrane organization#GO:0007009;transport#GO:0006810;plasma membrane phospholipid scrambling#GO:0017121;endomembrane system organization#GO:0010256;cellular component organization#GO:0016043;regulation of membrane lipid distribution#GO:0097035;phospholipid transport#GO:0015914;cellular process#GO:0009987;lipid transport#GO:0006869;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;biological regulation#GO:0065007;lipid translocation#GO:0034204;lipid localization#GO:0010876;phospholipid translocation#GO:0045332 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transporter#PC00227 CIOIN|Ensembl=ENSCING00000021832.1|UniProtKB=F6RW80 F6RW80 PTHR24039:SF58 FIBRILLIN-RELATED EGF-LIKE DOMAIN-CONTAINING PROTEIN extracellular matrix structural protein#PC00103 CIOIN|Ensembl=ENSCING00000021421.1|UniProtKB=H2XU03 H2XU03 PTHR13428:SF12 INNER NUCLEAR MEMBRANE PROTEIN MAN1 LEM DOMAIN CONTAINING PROTEIN INNER NUCLEAR MEMBRANE PROTEIN MAN1 CIOIN|Ensembl=ENSCING00000011247.1|UniProtKB=F7AY51 F7AY51 LOC100180780 PTHR19282:SF519 TETRASPANIN TETRASPANIN cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000024212.1|UniProtKB=H2XT12 H2XT12 PTHR16089:SF40 REST COREPRESSOR COREST PROTEIN-RELATED SUPPRESSOR OF ACTIVATED EGL-4 PROTEIN 1 molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714;protein-macromolecule adaptor activity#GO:0030674 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of biosynthetic process#GO:0009890;negative regulation of RNA metabolic process#GO:0051253;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;histone deacetylase complex#GO:0000118;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 chromatin/chromatin-binding, or -regulatory protein#PC00077 CIOIN|Ensembl=ENSCING00000006871.3|UniProtKB=A0A1W2W480 A0A1W2W480 LOC100176165 PTHR12461:SF37 HYPOXIA-INDUCIBLE FACTOR 1 ALPHA INHIBITOR-RELATED JMJC DOMAIN-CONTAINING PROTEIN protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000013811.2|UniProtKB=F6QRT7 F6QRT7 PTHR45840:SF2 RHOMBOID-RELATED PROTEIN PROTEIN RHOMBOID-RELATED CIOIN|Ensembl=ENSCING00000007494.3|UniProtKB=F6XVY9 F6XVY9 PTHR45622:SF60 UBIQUITIN-PROTEIN LIGASE E3A-RELATED UBIQUITIN-PROTEIN LIGASE E3A transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 Ubiquitin proteasome pathway#P00060>E3#P01490 CIOIN|Ensembl=ENSCING00000020354.1|UniProtKB=F6UWG2 F6UWG2 LOC100177164 PTHR24264:SF65 TRYPSIN-RELATED SRCR DOMAIN-CONTAINING PROTEIN hydrolase activity#GO:0016787;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 serine protease#PC00203;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000020754.1|UniProtKB=H2Y3K9 H2Y3K9 PTHR23382:SF3 MALATE DEHYDROGENASE MALATE DEHYDROGENASE, CYTOPLASMIC oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 cellular aromatic compound metabolic process#GO:0006725;dicarboxylic acid metabolic process#GO:0043648;pyridine nucleotide metabolic process#GO:0019362;nucleobase-containing compound metabolic process#GO:0006139;energy derivation by oxidation of organic compounds#GO:0015980;phosphorus metabolic process#GO:0006793;tricarboxylic acid cycle#GO:0006099;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;pyridine-containing compound metabolic process#GO:0072524;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular respiration#GO:0045333;aerobic respiration#GO:0009060;oxoacid metabolic process#GO:0043436;generation of precursor metabolites and energy#GO:0006091;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;nicotinamide nucleotide metabolic process#GO:0046496;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;carboxylic acid metabolic process#GO:0019752;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 dehydrogenase#PC00092;oxidoreductase#PC00176 TCA cycle#P00051>Malate Dehydrogenase#P01270 CIOIN|Ensembl=ENSCING00000002872.3|UniProtKB=Q8TA66 Q8TA66 CiNut PTHR24228:SF72 B2 BRADYKININ RECEPTOR/ANGIOTENSIN II RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 G-protein coupled receptor#PC00021 CIOIN|Ensembl=ENSCING00000019819.1|UniProtKB=H2Y0J1 H2Y0J1 PTHR13132:SF29 ALPHA- 1,6 -FUCOSYLTRANSFERASE ALPHA-(1,6)-FUCOSYLTRANSFERASE transferase activity#GO:0016740;fucosyltransferase activity#GO:0008417;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein glycosylation#GO:0006486;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein N-linked glycosylation#GO:0006487;protein metabolic process#GO:0019538;glycosylation#GO:0070085;glycoprotein metabolic process#GO:0009100;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 glycosyltransferase#PC00111 Notch signaling pathway#P00045>Neurotic#P01115 CIOIN|Ensembl=ENSCING00000013632.2|UniProtKB=F6UCM8 F6UCM8 PTHR19134:SF562 RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE PROTEIN-TYROSINE-PHOSPHATASE hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;protein tyrosine phosphatase activity#GO:0004725;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 protein phosphatase#PC00195;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000004434.3|UniProtKB=F6Y3G3 F6Y3G3 PTHR11486:SF160 FIBROBLAST GROWTH FACTOR FIBROBLAST GROWTH FACTOR 22-LIKE ISOFORM X1 molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;binding#GO:0005488;growth factor activity#GO:0008083;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;growth factor receptor binding#GO:0070851;protein binding#GO:0005515;signaling receptor binding#GO:0005102;fibroblast growth factor receptor binding#GO:0005104 positive regulation of gene expression#GO:0010628;regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;positive regulation of cell population proliferation#GO:0008284;positive regulation of protein modification process#GO:0031401;regulation of intracellular signal transduction#GO:1902531;response to fibroblast growth factor#GO:0071774;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;regulation of cell migration#GO:0030334;anatomical structure morphogenesis#GO:0009653;regulation of signal transduction#GO:0009966;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;cellular developmental process#GO:0048869;cellular response to endogenous stimulus#GO:0071495;positive regulation of phosphorus metabolic process#GO:0010562;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;positive regulation of cell communication#GO:0010647;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;fibroblast growth factor receptor signaling pathway#GO:0008543;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;regulation of locomotion#GO:0040012;response to growth factor#GO:0070848;animal organ development#GO:0048513;regulation of signaling#GO:0023051;developmental process#GO:0032502;positive regulation of MAPK cascade#GO:0043410;positive regulation of response to stimulus#GO:0048584;positive regulation of biosynthetic process#GO:0009891;cell differentiation#GO:0030154;response to endogenous stimulus#GO:0009719;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of intracellular signal transduction#GO:1902533;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;signaling#GO:0023052;regulation of cell communication#GO:0010646;positive regulation of protein phosphorylation#GO:0001934;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;regulation of cell population proliferation#GO:0042127;regulation of cell motility#GO:2000145;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;cellular response to growth factor stimulus#GO:0071363;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;animal organ morphogenesis#GO:0009887;cellular response to fibroblast growth factor stimulus#GO:0044344 cytoplasm#GO:0005737;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576;intracellular anatomical structure#GO:0005622 intercellular signal molecule#PC00207;growth factor#PC00112 CIOIN|Ensembl=ENSCING00000007233.3|UniProtKB=F6VKF0 F6VKF0 PTHR13847:SF287 SARCOSINE DEHYDROGENASE-RELATED FAD-DEPENDENT OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN 1 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 dehydrogenase#PC00092;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000012434.2|UniProtKB=F6VIA9 F6VIA9 LOC100176941 PTHR11595:SF21 EF-HAND AND COILED-COIL DOMAIN-CONTAINING FAMILY MEMBER ELONGATION FACTOR 1-BETA nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;translational elongation#GO:0006414;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 translation elongation factor#PC00222;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000008576.3|UniProtKB=F6X0G2 F6X0G2 PTHR12191:SF37 SOLUTE CARRIER FAMILY 39 ZINC TRANSPORTER FOI secondary active transmembrane transporter activity#GO:0015291;inorganic molecular entity transmembrane transporter activity#GO:0015318;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;symporter activity#GO:0015293;active monoatomic ion transmembrane transporter activity#GO:0022853;organic anion transmembrane transporter activity#GO:0008514;monoatomic cation transmembrane transporter activity#GO:0008324;inorganic cation transmembrane transporter activity#GO:0022890;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;homeostatic process#GO:0042592;monoatomic cation homeostasis#GO:0055080;inorganic ion transmembrane transport#GO:0098660;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;cellular process#GO:0009987;intracellular chemical homeostasis#GO:0055082;monoatomic ion homeostasis#GO:0050801;localization#GO:0051179;import across plasma membrane#GO:0098739;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation transport#GO:0006812;transition metal ion transport#GO:0000041;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;import into cell#GO:0098657 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000008457.3|UniProtKB=F6TRN8 F6TRN8 PTHR10350:SF6 NUCLEAR PORE COMPLEX PROTEIN NUP155 NUCLEAR PORE COMPLEX PROTEIN NUP155 structural molecule activity#GO:0005198;structural constituent of nuclear pore#GO:0017056 cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;protein localization to nucleus#GO:0034504;nucleic acid transport#GO:0050657;nitrogen compound transport#GO:0071705;establishment of protein localization#GO:0045184;RNA localization#GO:0006403;organic substance transport#GO:0071702;protein import into nucleus#GO:0006606;transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery#GO:0000972;establishment of localization#GO:0051234;RNA transport#GO:0050658;protein localization to organelle#GO:0033365;nuclear transport#GO:0051169;localization within membrane#GO:0051668;establishment of RNA localization#GO:0051236;protein localization to membrane#GO:0072657;establishment of protein localization to organelle#GO:0072594;cellular component organization#GO:0016043;cellular process#GO:0009987;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;nuclear export#GO:0051168;chromosome organization#GO:0051276;organelle organization#GO:0006996;nucleocytoplasmic transport#GO:0006913;nucleobase-containing compound transport#GO:0015931;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;import into nucleus#GO:0051170 envelope#GO:0031975;nuclear pore#GO:0005643;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear envelope#GO:0005635;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;organelle envelope#GO:0031967;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transporter#PC00227 CIOIN|Ensembl=ENSCING00000022579.1|UniProtKB=H2XK60 H2XK60 LOC100181405 PTHR43884:SF12 ACYL-COA DEHYDROGENASE ISOVALERYL-COA DEHYDROGENASE, MITOCHONDRIAL-RELATED oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 dehydrogenase#PC00092;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000012298.2|UniProtKB=F7AWK4 F7AWK4 PTHR11771:SF153 LIPOXYGENASE LIPOXYGENASE DOMAIN-CONTAINING PROTEIN oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;dioxygenase activity#GO:0051213 lipid metabolic process#GO:0006629;lipid oxidation#GO:0034440;cellular metabolic process#GO:0044237;lipid modification#GO:0030258;cellular lipid metabolic process#GO:0044255;cellular process#GO:0009987;metabolic process#GO:0008152;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704 oxygenase#PC00177;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000014122.2|UniProtKB=F6SR07 F6SR07 PTHR46842:SF1 TRANSMEMBRANE PROTEIN 266 TRANSMEMBRANE PROTEIN 266 CIOIN|Ensembl=ENSCING00000011450.2|UniProtKB=F6ZUZ2 F6ZUZ2 LOC100179576 PTHR12755:SF3 CLEAVAGE/POLYADENYLATION FACTOR IA SUBUNIT CLP1P POLYNUCLEOTIDE 5'-HYDROXYL-KINASE NOL9 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 mRNA polyadenylation factor#PC00146;RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000004842.3|UniProtKB=F6YX11 F6YX11 PTHR14255:SF4 CEREBLON PROTEIN CEREBLON protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;cullin-RING ubiquitin ligase complex#GO:0031461;transferase complex#GO:1990234;Cul4-RING E3 ubiquitin ligase complex#GO:0080008 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000021789.1|UniProtKB=H2XP31 H2XP31 PTHR36982:SF4 CLCA DOMAIN-CONTAINING PROTEIN CLCA DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000004042.3|UniProtKB=F6RXS5 F6RXS5 PTHR46118:SF4 PROTEIN ABHD11 PROTEIN ABHD11 CIOIN|Ensembl=ENSCING00000014865.2|UniProtKB=F7BFW8 F7BFW8 LOC100178903 PTHR11955:SF147 FATTY ACID BINDING PROTEIN FATTY ACID-BINDING PROTEIN, LIVER-LIKE fatty acid binding#GO:0005504;small molecule binding#GO:0036094;binding#GO:0005488;carboxylic acid binding#GO:0031406;lipid binding#GO:0008289;ion binding#GO:0043167;organic acid binding#GO:0043177;anion binding#GO:0043168 localization#GO:0051179;monocarboxylic acid transport#GO:0015718;organic substance transport#GO:0071702;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;organic anion transport#GO:0015711;fatty acid transport#GO:0015908;organic acid transport#GO:0015849;transport#GO:0006810;carboxylic acid transport#GO:0046942;lipid localization#GO:0010876;lipid transport#GO:0006869 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transfer/carrier protein#PC00219 CIOIN|Ensembl=ENSCING00000000616.3|UniProtKB=F6RRS1 F6RRS1 LOC100175005 PTHR13097:SF7 TRANSCRIPTION INITIATION FACTOR IIE, ALPHA SUBUNIT GENERAL TRANSCRIPTION FACTOR IIE SUBUNIT 1 RNA metabolism protein#PC00031;general transcription factor#PC00259 General transcription regulation#P00023>TFIIE#P00666;General transcription regulation#P00023>TFIIEalpha#P00669;Transcription regulation by bZIP transcription factor#P00055>TFIIE#P01395;Transcription regulation by bZIP transcription factor#P00055>TFIIEalpha#P01398 CIOIN|Ensembl=ENSCING00000008873.3|UniProtKB=F6QY33 F6QY33 PTHR46291:SF4 C2 DOMAIN-CONTAINING PROTEIN C2 CALCIUM-DEPENDENT DOMAIN-CONTAINING PROTEIN 4C-LIKE CIOIN|Ensembl=ENSCING00000020018.1|UniProtKB=Q1RLE2 Q1RLE2 Ci-ZF(C2H2)-89 PTHR24393:SF136 ZINC FINGER PROTEIN LD28458P-RELATED DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 CIOIN|Ensembl=ENSCING00000004824.3|UniProtKB=F6R8X1 F6R8X1 LOC100183367 PTHR11093:SF6 RUVB-RELATED REPTIN AND PONTIN RUVB-LIKE 1 ATP-dependent activity, acting on DNA#GO:0008094;catalytic activity, acting on a nucleic acid#GO:0140640;DNA helicase activity#GO:0003678;catalytic activity, acting on DNA#GO:0140097;helicase activity#GO:0004386;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;protein-DNA complex organization#GO:0071824;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;protein-containing complex assembly#GO:0065003;regulation of RNA biosynthetic process#GO:2001141;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;protein-RNA complex assembly#GO:0022618;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;protein-containing complex organization#GO:0043933;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;ribonucleoprotein complex biogenesis#GO:0022613;biological regulation#GO:0065007;chromatin organization#GO:0006325;protein-RNA complex organization#GO:0071826;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;chromatin remodeling#GO:0006338;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 histone acetyltransferase complex#GO:0000123;acetyltransferase complex#GO:1902493;chromatin#GO:0000785;protein-DNA complex#GO:0032993;catalytic complex#GO:1902494;NuA4 histone acetyltransferase complex#GO:0035267;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein acetyltransferase complex#GO:0031248;protein-containing complex#GO:0032991;chromosome#GO:0005694 CIOIN|Ensembl=ENSCING00000008933.3|UniProtKB=F6QA27 F6QA27 LOC100182618 PTHR16056:SF2 REGULATOR OF MICROTUBULE DYNAMICS PROTEIN TESTIS-EXPRESSED PROTEIN 10 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 CIOIN|Ensembl=ENSCING00000009474.3|UniProtKB=F7AEZ3 F7AEZ3 LOC100187168 PTHR42881:SF2 PROLYL ENDOPEPTIDASE PROLYL ENDOPEPTIDASE hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 serine protease#PC00203;protease#PC00190 Vasopressin synthesis#P04395>Endo Peptidase#P04596 CIOIN|Ensembl=ENSCING00000005154.3|UniProtKB=F6SKY6 F6SKY6 PTHR13328:SF4 NEGATIVE ELONGATION FACTOR A NELF-A NEGATIVE ELONGATION FACTOR A CIOIN|Ensembl=ENSCING00000011486.2|UniProtKB=F6UVD1 F6UVD1 LOC100176568 PTHR44500:SF1 DNAJ HOMOLOG SUBFAMILY C MEMBER 12 DNAJ HOMOLOG SUBFAMILY C MEMBER 12 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 chaperone#PC00072 CIOIN|Ensembl=ENSCING00000001513.3|UniProtKB=F7ATI9 F7ATI9 LOC100186956 PTHR21257:SF52 DELTA(14)-STEROL REDUCTASE DELTA(14)-STEROL REDUCTASE TM7SF2 oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor#GO:0016628 sterol metabolic process#GO:0016125;organic hydroxy compound metabolic process#GO:1901615;steroid metabolic process#GO:0008202;lipid metabolic process#GO:0006629;organic cyclic compound metabolic process#GO:1901360;organic hydroxy compound biosynthetic process#GO:1901617;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;lipid biosynthetic process#GO:0008610;steroid biosynthetic process#GO:0006694;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;sterol biosynthetic process#GO:0016126;metabolic process#GO:0008152 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 reductase#PC00198;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000005070.3|UniProtKB=Q4H3L6 Q4H3L6 Ci-ERF2 PTHR11849:SF59 ETS ETS DOMAIN-CONTAINING PROTEIN transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 CIOIN|Ensembl=ENSCING00000005130.3|UniProtKB=F6VY95 F6VY95 PTHR45742:SF8 COMPLEMENT COMPONENT C6 FLOCCULATION PROTEIN FLO11 complement component#PC00078 CIOIN|Ensembl=ENSCING00000005428.3|UniProtKB=Q6XZ10 Q6XZ10 LOC445729 PTHR11730:SF60 AMMONIUM TRANSPORTER RH50, ISOFORM D inorganic molecular entity transmembrane transporter activity#GO:0015318;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;inorganic cation transmembrane transporter activity#GO:0022890;channel activity#GO:0015267 localization#GO:0051179;inorganic ion homeostasis#GO:0098771;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;nitrogen compound transport#GO:0071705;homeostatic process#GO:0042592;inorganic ion transmembrane transport#GO:0098660;chemical homeostasis#GO:0048878;cellular process#GO:0009987 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 primary active transporter#PC00068;transporter#PC00227 CIOIN|Ensembl=ENSCING00000007551.3|UniProtKB=F6T8N6 F6T8N6 PTHR24223:SF456 ATP-BINDING CASSETTE SUB-FAMILY C MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN LETHAL(2)03659 transmembrane transporter activity#GO:0022857;primary active transmembrane transporter activity#GO:0015399;ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 localization#GO:0051179;establishment of localization#GO:0051234;cellular process#GO:0009987;transmembrane transport#GO:0055085;transport#GO:0006810 cellular anatomical entity#GO:0110165;membrane#GO:0016020 ATP-binding cassette (ABC) transporter#PC00003;transporter#PC00227 CIOIN|Ensembl=ENSCING00000000968.3|UniProtKB=F6YLU7 F6YLU7 LOC100184547 PTHR24276:SF91 POLYSERASE-RELATED AT26814P-RELATED hydrolase activity#GO:0016787;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171 serine protease#PC00203;protease#PC00190 CIOIN|Ensembl=ENSCING00000010012.3|UniProtKB=Q4H3L8 Q4H3L8 Ci-EphrinB PTHR11304:SF29 EPHRIN EPHRIN protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 neuron projection guidance#GO:0097485;signal transduction#GO:0007165;neurogenesis#GO:0022008;cell projection organization#GO:0030030;developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cellular anatomical entity morphogenesis#GO:0032989;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;axon guidance#GO:0007411;anatomical structure morphogenesis#GO:0009653;neuron differentiation#GO:0030182;axonogenesis#GO:0007409;plasma membrane bounded cell projection morphogenesis#GO:0120039;signaling#GO:0023052;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;multicellular organism development#GO:0007275;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;cell communication#GO:0007154;cellular process#GO:0009987;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;neuron projection development#GO:0031175;axon development#GO:0061564;enzyme-linked receptor protein signaling pathway#GO:0007167;cell morphogenesis involved in neuron differentiation#GO:0048667;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 membrane-bound signaling molecule#PC00152;intercellular signal molecule#PC00207 CIOIN|Ensembl=ENSCING00000004641.3|UniProtKB=Q1RLH9 Q1RLH9 Ci-ZF(C2H2)-46 PTHR16515:SF59 PR DOMAIN ZINC FINGER PROTEIN PR DOMAIN ZINC FINGER PROTEIN 1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cell fate commitment#GO:0045165;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 CIOIN|Ensembl=ENSCING00000019374.1|UniProtKB=H2XUU8 H2XUU8 PTHR10332:SF88 EQUILIBRATIVE NUCLEOSIDE TRANSPORTER EQUILIBRATIVE NUCLEOSIDE TRANSPORTER 1, ISOFORM A carbohydrate derivative transmembrane transporter activity#GO:1901505;nucleobase-containing compound transmembrane transporter activity#GO:0015932;nucleoside transmembrane transporter activity#GO:0005337;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 transporter#PC00227 CIOIN|Ensembl=ENSCING00000002315.3|UniProtKB=F6PP92 F6PP92 PTHR23291:SF32 BAX INHIBITOR-RELATED BAX INHIBITOR 1 cellular anatomical entity#GO:0110165;membrane#GO:0016020 ion channel#PC00133;transporter#PC00227 Apoptosis signaling pathway#P00006>Bi1#P00277 CIOIN|Ensembl=ENSCING00000025201.1|UniProtKB=Q8HIN7 Q8HIN7 NADH2 PTHR46552:SF1 NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 2 NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 2 transmembrane transporter activity#GO:0022857;primary active transmembrane transporter activity#GO:0015399;electron transfer activity#GO:0009055;catalytic activity#GO:0003824;NADH dehydrogenase activity#GO:0003954;oxidoreductase activity, acting on NAD(P)H#GO:0016651;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804;oxidoreductase activity#GO:0016491 mitochondrial ATP synthesis coupled electron transport#GO:0042775;aerobic respiration#GO:0009060;cellular respiration#GO:0045333;mitochondrial electron transport, NADH to ubiquinone#GO:0006120;respiratory electron transport chain#GO:0022904;aerobic electron transport chain#GO:0019646;oxidative phosphorylation#GO:0006119;generation of precursor metabolites and energy#GO:0006091;electron transport chain#GO:0022900;ATP synthesis coupled electron transport#GO:0042773;cellular metabolic process#GO:0044237;cellular process#GO:0009987;energy derivation by oxidation of organic compounds#GO:0015980;metabolic process#GO:0008152 envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;respiratory chain complex#GO:0098803;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transporter complex#GO:1990351;oxidoreductase complex#GO:1990204;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;respirasome#GO:0070469;mitochondrial respiratory chain complex I#GO:0005747;protein-containing complex#GO:0032991;mitochondrial envelope#GO:0005740;mitochondrial respirasome#GO:0005746;transmembrane transporter complex#GO:1902495;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227;respiratory chain complex I#GO:0045271;NADH dehydrogenase complex#GO:0030964;mitochondrial protein-containing complex#GO:0098798 oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000002523.3|UniProtKB=F6XS97 F6XS97 PTHR23189:SF114 RNA RECOGNITION MOTIF-CONTAINING SAP DNA-BINDING DOMAIN-CONTAINING PROTEIN RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000020120.1|UniProtKB=H2XY92 H2XY92 LOC101243096 PTHR13826:SF14 INTESTINAL TREFOIL FACTOR-RELATED TREFOIL FACTOR 2 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 CIOIN|Ensembl=ENSCING00000018884.1|UniProtKB=H2XSV6 H2XSV6 PTHR11769:SF35 HYALURONIDASE HYALURONIDASE glycosaminoglycan metabolic process#GO:0030203;carbohydrate derivative metabolic process#GO:1901135;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;carbohydrate derivative catabolic process#GO:1901136;organonitrogen compound metabolic process#GO:1901564;catabolic process#GO:0009056;organonitrogen compound catabolic process#GO:1901565;aminoglycan metabolic process#GO:0006022;organic substance catabolic process#GO:1901575;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 glycosidase#PC00110;metabolite interconversion enzyme#PC00262;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000005447.3|UniProtKB=A0A1W2W7E4 A0A1W2W7E4 LOC100187383 PTHR11545:SF2 RIBOSOMAL PROTEIN L13 LARGE RIBOSOMAL SUBUNIT PROTEIN UL13M structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;structural molecule activity#GO:0005198;binding#GO:0005488;organic cyclic compound binding#GO:0097159 negative regulation of gene expression#GO:0010629;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;negative regulation of biosynthetic process#GO:0009890;regulation of amide metabolic process#GO:0034248;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of translation#GO:0017148;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;post-transcriptional regulation of gene expression#GO:0010608;biological regulation#GO:0065007;regulation of translation#GO:0006417;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000007279.3|UniProtKB=F6SVM4 F6SVM4 PTHR13022:SF0 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT 11 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT K translation regulator activity#GO:0045182;nucleic acid binding#GO:0003676;translation regulator activity, nucleic acid binding#GO:0090079;translation initiation factor activity#GO:0003743;binding#GO:0005488;organic cyclic compound binding#GO:0097159;translation factor activity, RNA binding#GO:0008135 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical entity#GO:0110165;eukaryotic translation initiation factor 3 complex#GO:0005852;intracellular anatomical structure#GO:0005622 translation initiation factor#PC00224;translation factor#PC00223;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000006792.3|UniProtKB=F6VDU4 F6VDU4 PTHR10117:SF54 TRANSIENT RECEPTOR POTENTIAL CHANNEL TRANSIENT RECEPTOR POTENTIAL-GAMMA PROTEIN calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;calcium channel activity#GO:0005262;small molecule binding#GO:0036094;binding#GO:0005488;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;anion binding#GO:0043168;ion binding#GO:0043167;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;alcohol binding#GO:0043178 inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;calcium ion transmembrane transport#GO:0070588;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;homeostatic process#GO:0042592;monoatomic cation homeostasis#GO:0055080;inorganic ion transmembrane transport#GO:0098660;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;cellular process#GO:0009987;regulation of cytosolic calcium ion concentration#GO:0051480;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;calcium ion transport#GO:0006816;monoatomic ion homeostasis#GO:0050801;localization#GO:0051179;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation transport#GO:0006812;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;cation channel complex#GO:0034703;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 Alzheimer disease-presenilin pathway#P00004>Capacitative calcium channels#P00124 CIOIN|Ensembl=ENSCING00000009030.3|UniProtKB=F6R7T5 F6R7T5 PTHR13808:SF1 CBP/P300-RELATED HISTONE ACETYLTRANSFERASE histone modifying activity#GO:0140993;nucleic acid binding#GO:0003676;acyltransferase activity#GO:0016746;peptide N-acetyltransferase activity#GO:0034212;binding#GO:0005488;catalytic activity#GO:0003824;protein-macromolecule adaptor activity#GO:0030674;transcription coactivator activity#GO:0003713;N-acyltransferase activity#GO:0016410;histone acetyltransferase activity#GO:0004402;transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;molecular adaptor activity#GO:0060090;N-acetyltransferase activity#GO:0008080;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;chromatin DNA binding#GO:0031490;transferase activity#GO:0016740;acetyltransferase activity#GO:0016407;peptide-lysine-N-acetyltransferase activity#GO:0061733;organic cyclic compound binding#GO:0097159;chromatin binding#GO:0003682;DNA binding#GO:0003677;protein-containing complex binding#GO:0044877;catalytic activity, acting on a protein#GO:0140096 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of biosynthetic process#GO:0009889;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of RNA metabolic process#GO:0051254;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 histone acetyltransferase complex#GO:0000123;acetyltransferase complex#GO:1902493;protein-DNA complex#GO:0032993;catalytic complex#GO:1902494;chromatin#GO:0000785;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein acetyltransferase complex#GO:0031248;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;chromosome#GO:0005694 histone modifying enzyme#PC00261 DPP signaling pathway#P06213>NEJ#P06284;TGF-beta signaling pathway#P00052>Co-activators corepressors#P01282;SCW signaling pathway#P06216>NEJ#P06328;GBB signaling pathway#P06214>NEJ#P06295;BMP/activin signaling pathway-drosophila#P06211>NEJ#P06246;p53 pathway#P00059>CBP#P04623;Wnt signaling pathway#P00057>CBP#P01448;Transcription regulation by bZIP transcription factor#P00055>CBP/P300#P01387;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>CREB#P00713;DPP-SCW signaling pathway#P06212>NEJ#P06260;Huntington disease#P00029>CBP#P00777 CIOIN|Ensembl=ENSCING00000009346.3|UniProtKB=F6Z3Q1 F6Z3Q1 LOC100184082 PTHR22802:SF457 C-TYPE LECTIN SUPERFAMILY MEMBER ASIALOGLYCOPROTEIN RECEPTOR-LIKE 1 membrane traffic protein#PC00150 CIOIN|Ensembl=ENSCING00000007878.3|UniProtKB=F6TGH1 F6TGH1 LOC101243528 PTHR19211:SF117 ATP-BINDING TRANSPORT PROTEIN-RELATED ATP-BINDING CASSETTE SUB-FAMILY F MEMBER 3 nucleotide binding#GO:0000166;carbohydrate derivative binding#GO:0097367;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;anion binding#GO:0043168;ATP binding#GO:0005524 translation elongation factor#PC00222;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000007195.3|UniProtKB=F6YRX2 F6YRX2 PTHR24379:SF121 KRAB AND ZINC FINGER DOMAIN-CONTAINING C2H2-TYPE DOMAIN-CONTAINING PROTEIN C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 CIOIN|Ensembl=ENSCING00000023875.1|UniProtKB=H2XMZ3 H2XMZ3 LOC101242732 PTHR24543:SF325 MULTICOPPER OXIDASE-RELATED F5_8 TYPE C DOMAIN-CONTAINING PROTEIN oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000020743.1|UniProtKB=H2XS89 H2XS89 LOC100177381 PTHR18860:SF159 14-3-3 PROTEIN 14-3-3 PROTEIN ZETA localization#GO:0051179;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular localization#GO:0051641;cellular response to stimulus#GO:0051716;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052;protein localization#GO:0008104 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 Parkinson disease#P00049>14-3-3#P01238;FGF signaling pathway#P00021>14-3-3#P00624;EGF receptor signaling pathway#P00018>14-3-3#P00539;PI3 kinase pathway#P00048>14-3-3#P01206 CIOIN|Ensembl=ENSCING00000002160.3|UniProtKB=F6QGB8 F6QGB8 LOC100177815 PTHR20648:SF0 ELONGIN-C ELONGIN-C molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;transcription elongation factor complex#GO:0008023;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031;general transcription factor#PC00259 CIOIN|Ensembl=ENSCING00000014616.2|UniProtKB=F6SBJ2 F6SBJ2 PTHR13295:SF4 GLUTAMATE CYSTEINE LIGASE REGULATORY SUBUNIT GLUTAMATE--CYSTEINE LIGASE REGULATORY SUBUNIT enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 sulfur compound metabolic process#GO:0006790;positive regulation of catalytic activity#GO:0043085;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;positive regulation of molecular function#GO:0044093;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;glutathione metabolic process#GO:0006749;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;regulation of molecular function#GO:0065009;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;cellular modified amino acid metabolic process#GO:0006575;biological regulation#GO:0065007;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622 ligase#PC00142;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000013967.2|UniProtKB=F6RNX9 F6RNX9 PTHR46012:SF2 IP22168P IP22168P UDP-xylosyltransferase activity#GO:0035252;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;xylosyltransferase activity#GO:0042285;pentosyltransferase activity#GO:0016763;UDP-glycosyltransferase activity#GO:0008194 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein glycosylation#GO:0006486;protein O-linked glycosylation#GO:0006493;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;glycosylation#GO:0070085;glycoprotein metabolic process#GO:0009100;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 CIOIN|Ensembl=ENSCING00000007724.3|UniProtKB=F6ZIT4 F6ZIT4 PTHR13902:SF67 SERINE/THREONINE-PROTEIN KINASE WNK WITH NO LYSINE -RELATED NUCLEAR RECEPTOR-BINDING PROTEIN HOMOLOG transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;nitrogen compound metabolic process#GO:0006807;biological regulation#GO:0065007;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000008712.3|UniProtKB=F6WCC6 F6WCC6 PTHR13556:SF2 TRANSCRIPTIONAL ADAPTER 3-RELATED TRANSCRIPTIONAL ADAPTER 3 transcription coactivator activity#GO:0003713;molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;protein-macromolecule adaptor activity#GO:0030674 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 SAGA-type complex#GO:0070461;peptidase complex#GO:1905368;histone acetyltransferase complex#GO:0000123;acetyltransferase complex#GO:1902493;chromatin#GO:0000785;protein-DNA complex#GO:0032993;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein acetyltransferase complex#GO:0031248;protein-containing complex#GO:0032991;chromosome#GO:0005694;SAGA complex#GO:0000124 chromatin/chromatin-binding, or -regulatory protein#PC00077;histone modifying enzyme#PC00261 CIOIN|Ensembl=ENSCING00000015385.2|UniProtKB=F6XX66 F6XX66 PTHR10026:SF13 CYCLIN LD24704P protein kinase regulator activity#GO:0019887;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207 regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 kinase activator#PC00138 CIOIN|Ensembl=ENSCING00000018026.1|UniProtKB=H2XS94 H2XS94 LOC100180782 PTHR11214:SF283 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE N-ACETYLLACTOSAMINIDE BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE 4-LIKE transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;protein O-linked glycosylation#GO:0006493;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 bounding membrane of organelle#GO:0098588;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;Golgi membrane#GO:0000139;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111 CIOIN|Ensembl=ENSCING00000024332.1|UniProtKB=H2XTU4 H2XTU4 PTHR36177:SF1 OCRE DOMAIN-CONTAINING PROTEIN OCRE DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000006956.3|UniProtKB=H2XR37 H2XR37 LOC100182146 PTHR14247:SF8 BREAST CANCER ANTI-ESTROGEN RESISTANCE PROTEIN 3 HOMOLOG-LIKE PROTEIN RAS-GEF DOMAIN-CONTAINING PROTEIN positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of protein phosphorylation#GO:0001934;positive regulation of phosphorylation#GO:0042327;regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of phosphorus metabolic process#GO:0010562;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of protein modification process#GO:0031401;positive regulation of cellular process#GO:0048522;regulation of phosphorus metabolic process#GO:0051174;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;positive regulation of protein metabolic process#GO:0051247;positive regulation of phosphate metabolic process#GO:0045937;positive regulation of metabolic process#GO:0009893;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of protein phosphorylation#GO:0001932;biological regulation#GO:0065007;regulation of phosphorylation#GO:0042325;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 CIOIN|Ensembl=ENSCING00000004887.3|UniProtKB=F6SP00 F6SP00 LOC100181454 PTHR40710:SF1 RIKEN CDNA E230025N22 GENE RIKEN CDNA E230025N22 GENE CIOIN|Ensembl=ENSCING00000023569.1|UniProtKB=H2XK64 H2XK64 PTHR23503:SF8 SOLUTE CARRIER FAMILY 2 FACILITATED GLUCOSE TRANSPORTER PROTEIN 1 transmembrane transporter activity#GO:0022857;sugar transmembrane transporter activity#GO:0051119;transporter activity#GO:0005215;carbohydrate transmembrane transporter activity#GO:0015144 localization#GO:0051179;organic substance transport#GO:0071702;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810;cellular process#GO:0009987;carbohydrate transmembrane transport#GO:0034219;carbohydrate transport#GO:0008643 cellular anatomical entity#GO:0110165;membrane#GO:0016020 secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000023636.1|UniProtKB=H2XJZ8 H2XJZ8 PTHR16165:SF5 NXPE FAMILY MEMBER NXPE FAMILY MEMBER 3 CIOIN|Ensembl=ENSCING00000009599.3|UniProtKB=Q4H2M5 Q4H2M5 Ci-Wnt3 PTHR12027:SF100 WNT RELATED PROTEIN WNT molecular function activator activity#GO:0140677;binding#GO:0005488;molecular function regulator activity#GO:0098772;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;cytokine activity#GO:0005125;G protein-coupled receptor binding#GO:0001664;signaling receptor binding#GO:0005102 cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;neurogenesis#GO:0022008;developmental process#GO:0032502;multicellular organism development#GO:0007275;cell communication#GO:0007154;cell fate commitment#GO:0045165;cell-cell signaling by wnt#GO:0198738;nervous system development#GO:0007399;cellular process#GO:0009987;regulation of biological process#GO:0050789;system development#GO:0048731;response to stimulus#GO:0050896;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;neuron differentiation#GO:0030182;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;cell-cell signaling#GO:0007267;signaling#GO:0023052;canonical Wnt signaling pathway#GO:0060070;Wnt signaling pathway#GO:0016055 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 intercellular signal molecule#PC00207 Wnt signaling pathway#P00057>Wnt#P01444;Alzheimer disease-presenilin pathway#P00004>Wnt#P00142;Cadherin signaling pathway#P00012>Wnt#P00474 CIOIN|Ensembl=ENSCING00000002138.3|UniProtKB=F6WQS9 F6WQS9 nachr PTHR18945:SF924 NEUROTRANSMITTER GATED ION CHANNEL NEURONAL ACETYLCHOLINE RECEPTOR SUBUNIT BETA-4-LIKE ISOFORM X1 transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;signaling receptor activity#GO:0038023;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;neurotransmitter receptor activity#GO:0030594;ligand-gated monoatomic ion channel activity#GO:0015276;transporter activity#GO:0005215;channel activity#GO:0015267;transmembrane signaling receptor activity#GO:0004888;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;molecular transducer activity#GO:0060089;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;ligand-gated channel activity#GO:0022834 response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;transmembrane transport#GO:0055085;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;membrane depolarization#GO:0051899;transport#GO:0006810;regulation of membrane potential#GO:0042391;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to nitrogen compound#GO:1901699;localization#GO:0051179;regulation of biological process#GO:0050789;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;cellular response to oxygen-containing compound#GO:1901701;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;synaptic signaling#GO:0099536;monoatomic ion transport#GO:0006811;signaling#GO:0023052;cell-cell signaling#GO:0007267;acetylcholine receptor signaling pathway#GO:0095500 membrane protein complex#GO:0098796;synapse#GO:0045202;plasma membrane signaling receptor complex#GO:0098802;transporter complex#GO:1990351;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;receptor complex#GO:0043235;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;neuron projection#GO:0043005;transmembrane transporter complex#GO:1902495;cell projection#GO:0042995;plasma membrane#GO:0005886 ligand-gated ion channel#PC00141;ion channel#PC00133;transporter#PC00227 CIOIN|Ensembl=ENSCING00000005665.3|UniProtKB=F6Y1N2 F6Y1N2 PTHR12785:SF6 SPLICING FACTOR 3B SPLICING FACTOR 3B SUBUNIT 2 RNA splicing factor#PC00148;RNA processing factor#PC00147 CIOIN|Ensembl=ENSCING00000007029.2|UniProtKB=F6ZWA3 F6ZWA3 PTHR12442:SF7 DYNEIN INTERMEDIATE CHAIN DYNEIN AXONEMAL INTERMEDIATE CHAIN 2 protein binding#GO:0005515;binding#GO:0005488 cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;outer dynein arm assembly#GO:0036158;cell projection organization#GO:0030030;microtubule cytoskeleton organization#GO:0000226;microtubule-based movement#GO:0007018;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;axoneme assembly#GO:0035082;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031;cilium movement#GO:0003341;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;microtubule bundle formation#GO:0001578;axonemal dynein complex assembly#GO:0070286;cytoskeleton organization#GO:0007010;plasma membrane bounded cell projection assembly#GO:0120031 axoneme#GO:0005930;outer dynein arm#GO:0036157;catalytic complex#GO:1902494;cytoplasmic region#GO:0099568;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;microtubule associated complex#GO:0005875;axonemal dynein complex#GO:0005858;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;ciliary plasm#GO:0097014;plasma membrane bounded cell projection cytoplasm#GO:0032838;membrane-bounded organelle#GO:0043227;dynein complex#GO:0030286;cell projection#GO:0042995;cytoskeleton#GO:0005856;cilium#GO:0005929 microtubule or microtubule-binding cytoskeletal protein#PC00157 Huntington disease#P00029>Dynein complex#P00774 CIOIN|Ensembl=ENSCING00000018421.1|UniProtKB=H2Y3K6 H2Y3K6 PTHR20766:SF3 LARGE NEUTRAL AMINO ACIDS TRANSPORTER SMALL SUBUNIT 4-LIKE ISOFORM X1 LARGE NEUTRAL AMINO ACIDS TRANSPORTER SMALL SUBUNIT 4-LIKE ISOFORM X1 transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;organic acid transmembrane transporter activity#GO:0005342;L-amino acid transmembrane transporter activity#GO:0015179;organic anion transmembrane transporter activity#GO:0008514;amino acid transmembrane transporter activity#GO:0015171;neutral L-amino acid transmembrane transporter activity#GO:0015175;transporter activity#GO:0005215 localization#GO:0051179;neutral amino acid transport#GO:0015804;organic substance transport#GO:0071702;establishment of localization#GO:0051234;amino acid transport#GO:0006865;organic anion transport#GO:0015711;organic acid transport#GO:0015849;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942 CIOIN|Ensembl=ENSCING00000008802.3|UniProtKB=F6SC79 F6SC79 LOC100183262 PTHR37404:SF1 HCG1796489 HCG1796489 CIOIN|Ensembl=ENSCING00000016400.2|UniProtKB=F6S4L9 F6S4L9 PTHR12458:SF7 ORF PROTEIN PROTEIN CFAP20DC CIOIN|Ensembl=ENSCING00000022078.1|UniProtKB=H2XLM3 H2XLM3 PTHR46513:SF13 VITELLOGENIN RECEPTOR-LIKE PROTEIN-RELATED-RELATED EGF-LIKE DOMAIN-CONTAINING PROTEIN transmembrane signal receptor#PC00197 CIOIN|Ensembl=ENSCING00000008962.3|UniProtKB=F6Q5L2 F6Q5L2 PTHR43462:SF1 ALANYL-TRNA EDITING PROTEIN ALANYL-TRNA EDITING PROTEIN AARSD1 RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000004987.3|UniProtKB=F6WMB2 F6WMB2 PTHR44167:SF24 OVARIAN-SPECIFIC SERINE/THREONINE-PROTEIN KINASE LOK-RELATED SERINE_THREONINE-PROTEIN KINASE CHK2 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 p53 pathway#P00059>Chk2#P01484 CIOIN|Ensembl=ENSCING00000019027.1|UniProtKB=H2XL32 H2XL32 PTHR11616:SF321 SODIUM/CHLORIDE DEPENDENT TRANSPORTER SODIUM-DEPENDENT NUTRIENT AMINO ACID TRANSPORTER 1-RELATED inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;organic acid:sodium symporter activity#GO:0005343;organic acid transmembrane transporter activity#GO:0005342;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;organic anion transmembrane transporter activity#GO:0008514;monoatomic cation transmembrane transporter activity#GO:0008324;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;amino acid:sodium symporter activity#GO:0005283;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;metal ion transmembrane transporter activity#GO:0046873;active monoatomic ion transmembrane transporter activity#GO:0022853;amino acid transmembrane transporter activity#GO:0015171;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;organic anion transport#GO:0015711;amino acid transport#GO:0006865;organic acid transport#GO:0015849;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;amino acid import across plasma membrane#GO:0089718;carboxylic acid transmembrane transport#GO:1905039;localization#GO:0051179;organic substance transport#GO:0071702;import across plasma membrane#GO:0098739;amino acid transmembrane transport#GO:0003333;sodium ion transport#GO:0006814;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transport#GO:0006812;organic acid transmembrane transport#GO:1903825;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;import into cell#GO:0098657;sodium ion transmembrane transport#GO:0035725 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 primary active transporter#PC00068;transporter#PC00227 Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>CHT1#P01084 CIOIN|Ensembl=ENSCING00000008209.3|UniProtKB=F6PIZ2 F6PIZ2 PTHR45624:SF4 MITOCHONDRIAL BASIC AMINO ACIDS TRANSPORTER-RELATED CONGESTED-LIKE TRACHEA PROTEIN-RELATED transmembrane transporter activity#GO:0022857;organic cation transmembrane transporter activity#GO:0015101;transporter activity#GO:0005215 localization#GO:0051179;mitochondrial transport#GO:0006839;organic substance transport#GO:0071702;quaternary ammonium group transport#GO:0015697;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;organic cation transport#GO:0015695;transport#GO:0006810;nitrogen compound transport#GO:0071705;cellular process#GO:0009987 envelope#GO:0031975;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transporter#PC00227 CIOIN|Ensembl=ENSCING00000009190.3|UniProtKB=F6YLY7 F6YLY7 PTHR23023:SF226 DIMETHYLANILINE MONOOXYGENASE FLAVIN-CONTAINING MONOOXYGENASE oxygenase#PC00177;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000023650.1|UniProtKB=F6QWZ9 F6QWZ9 PTHR11929:SF145 ALPHA- 1,3 -FUCOSYLTRANSFERASE ALPHA-(1,3)-FUCOSYLTRANSFERASE FUT-1 transferase activity#GO:0016740;fucosyltransferase activity#GO:0008417;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 glycosylation#GO:0070085;metabolic process#GO:0008152 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000005478.3|UniProtKB=F6WAG8 F6WAG8 LOC100186995 PTHR11941:SF54 ENOYL-COA HYDRATASE-RELATED ENOYL-COA HYDRATASE, MITOCHONDRIAL lipid metabolic process#GO:0006629;oxoacid metabolic process#GO:0043436;cellular metabolic process#GO:0044237;lipid oxidation#GO:0034440;lipid modification#GO:0030258;lipid catabolic process#GO:0016042;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;fatty acid catabolic process#GO:0009062;primary metabolic process#GO:0044238;fatty acid metabolic process#GO:0006631;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;fatty acid beta-oxidation#GO:0006635;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;cellular lipid metabolic process#GO:0044255;carboxylic acid catabolic process#GO:0046395;cellular lipid catabolic process#GO:0044242;carboxylic acid metabolic process#GO:0019752;cellular catabolic process#GO:0044248;monocarboxylic acid catabolic process#GO:0072329;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 hydratase#PC00120 Succinate to proprionate conversion#P02777>Methylmalonyl-CoA decarboxylase#P03163 CIOIN|Ensembl=ENSCING00000004820.3|UniProtKB=F6R8V3 F6R8V3 PTHR14005:SF0 EUKARYOTIC TRANSLATION INITIATION FACTOR 3, THETA SUBUNIT EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT A nucleic acid binding#GO:0003676;RNA binding#GO:0003723;translation regulator activity#GO:0045182;binding#GO:0005488;organic cyclic compound binding#GO:0097159;translation initiation factor activity#GO:0003743;mRNA binding#GO:0003729;translation regulator activity, nucleic acid binding#GO:0090079;translation factor activity, RNA binding#GO:0008135 cellular component biogenesis#GO:0044085;peptide metabolic process#GO:0006518;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;translation#GO:0006412;protein-RNA complex assembly#GO:0022618;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular component assembly#GO:0022607;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cytoplasmic translation#GO:0002181;cellular component organization#GO:0016043;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;cytoplasmic translational initiation#GO:0002183;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;cellular component organization or biogenesis#GO:0071840;peptide biosynthetic process#GO:0043043;protein-containing complex organization#GO:0043933;ribonucleoprotein complex biogenesis#GO:0022613;translational initiation#GO:0006413;protein-RNA complex organization#GO:0071826 cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;eukaryotic translation initiation factor 3 complex#GO:0005852;intracellular anatomical structure#GO:0005622 translation initiation factor#PC00224;translation factor#PC00223;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000008054.3|UniProtKB=F6S414 F6S414 PTHR35982:SF1 AGAP005361-PA SPIROCYCLASE, AVEC FAMILY CIOIN|Ensembl=ENSCING00000014583.1|UniProtKB=F6SYT5 F6SYT5 PTHR11106:SF111 GANGLIOSIDE INDUCED DIFFERENTIATION ASSOCIATED PROTEIN 2-RELATED MACRO DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000002822.3|UniProtKB=F6WZ68 F6WZ68 LOC100184096 PTHR21538:SF23 ANILLIN/RHOTEKIN RTKN ANILLIN cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cell division#GO:0051301;actomyosin contractile ring assembly#GO:0000915;cell cycle process#GO:0022402;actomyosin structure organization#GO:0031032;cellular component organization#GO:0016043;cellular process#GO:0009987;cytokinetic process#GO:0032506;mitotic cell cycle process#GO:1903047;cellular component organization or biogenesis#GO:0071840;mitotic cytokinesis#GO:0000281;mitotic cell cycle#GO:0000278;actin filament-based process#GO:0030029;organelle organization#GO:0006996;cortical cytoskeleton organization#GO:0030865;cytoskeleton-dependent cytokinesis#GO:0061640;cell cycle#GO:0007049;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;cytokinesis#GO:0000910;cortical actin cytoskeleton organization#GO:0030866;septin cytoskeleton organization#GO:0032185 actomyosin contractile ring#GO:0005826;cortical cytoskeleton#GO:0030863;cell cortex#GO:0005938;cell periphery#GO:0071944;cortical actin cytoskeleton#GO:0030864;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cell division site#GO:0032153;contractile ring#GO:0070938;cytoskeleton#GO:0005856 cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165 CIOIN|Ensembl=ENSCING00000003015.3|UniProtKB=F6QEX4 F6QEX4 zf(c2h2)-10 PTHR24390:SF244 ZINC FINGER PROTEIN LD33778P-RELATED sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 CIOIN|Ensembl=ENSCING00000005034.3|UniProtKB=F6T9R1 F6T9R1 LOC100178199 PTHR11759:SF1 40S RIBOSOMAL PROTEIN S14/30S RIBOSOMAL PROTEIN S11 40S RIBOSOMAL PROTEIN S14 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic small ribosomal subunit#GO:0022627;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;small ribosomal subunit#GO:0015935;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000007260.3|UniProtKB=F6S7U7 F6S7U7 PTHR11606:SF13 GLUTAMATE DEHYDROGENASE GLUTAMATE DEHYDROGENASE 1, MITOCHONDRIAL catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 oxoacid metabolic process#GO:0043436;proteinogenic amino acid metabolic process#GO:0170039;dicarboxylic acid metabolic process#GO:0043648;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;amino acid catabolic process#GO:0009063;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;nitrogen compound metabolic process#GO:0006807;glutamate metabolic process#GO:0006536;alpha-amino acid metabolic process#GO:1901605;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;L-amino acid metabolic process#GO:0170033;carboxylic acid metabolic process#GO:0019752;amino acid metabolic process#GO:0006520;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152 dehydrogenase#PC00092;oxidoreductase#PC00176 Glutamine glutamate conversion#P02745>Glutamate Dehydrogenase#P02967 CIOIN|Ensembl=ENSCING00000019888.1|UniProtKB=H2XJX9 H2XJX9 PTHR19282:SF504 TETRASPANIN TETRASPANIN cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000004652.3|UniProtKB=F6RMT1 F6RMT1 PTHR12856:SF0 TRANSCRIPTION INITIATION FACTOR IIH-RELATED GENERAL TRANSCRIPTION FACTOR IIH SUBUNIT 1 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;DNA-templated transcription#GO:0006351;RNA metabolic process#GO:0016070;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;DNA damage response#GO:0006974;transcription by RNA polymerase I#GO:0006360;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;cellular response to stress#GO:0033554;transcription by RNA polymerase II#GO:0006366;DNA metabolic process#GO:0006259 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;DNA-directed RNA polymerase complex#GO:0000428;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nucleoplasm#GO:0005654;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;serine/threonine protein kinase complex#GO:1902554;RNA polymerase II transcription regulator complex#GO:0090575;protein kinase complex#GO:1902911;transcription factor TFIIH core complex#GO:0000439;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622;RNA polymerase II, holoenzyme#GO:0016591;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;transcription regulator complex#GO:0005667;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;transcription factor TFIIH holo complex#GO:0005675;nuclear protein-containing complex#GO:0140513 general transcription factor#PC00259 Transcription regulation by bZIP transcription factor#P00055>TFIIH complex#P01392;General transcription regulation#P00023>TFIIH complex#P00664 CIOIN|Ensembl=ENSCING00000009432.3|UniProtKB=F6SXW5 F6SXW5 PTHR23101:SF25 RAB GDP/GTP EXCHANGE FACTOR GTPASE-ACTIVATING PROTEIN AND VPS9 DOMAIN-CONTAINING PROTEIN 1 nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;binding#GO:0005488;molecular function regulator activity#GO:0098772;enzyme binding#GO:0019899;protein binding#GO:0005515;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;guanyl-nucleotide exchange factor activity#GO:0005085 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;endocytic vesicle#GO:0030139;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 CIOIN|Ensembl=ENSCING00000016659.2|UniProtKB=F7BMK2 F7BMK2 LOC100182621 PTHR10044:SF139 INHIBITOR OF APOPTOSIS DEATH-ASSOCIATED INHIBITOR OF APOPTOSIS 2 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protease inhibitor#PC00191 CIOIN|Ensembl=ENSCING00000007806.3|UniProtKB=Q8T893 Q8T893 CALX PTHR23055:SF60 CALCIUM BINDING PROTEINS CALAXIN cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488 calmodulin-related#PC00061 CIOIN|Ensembl=ENSCING00000016265.2|UniProtKB=F6Z7E0 F6Z7E0 KATNB1 PTHR19845:SF0 KATANIN P80 SUBUNIT KATANIN P80 WD40 REPEAT-CONTAINING SUBUNIT B1 cellular component organization or biogenesis#GO:0071840;cellular component disassembly#GO:0022411;protein-containing complex disassembly#GO:0032984;microtubule-based process#GO:0007017;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;supramolecular fiber organization#GO:0097435;microtubule depolymerization#GO:0007019;microtubule cytoskeleton organization#GO:0000226;cytoskeleton organization#GO:0007010;protein depolymerization#GO:0051261;cellular component organization#GO:0016043;cellular process#GO:0009987;microtubule polymerization or depolymerization#GO:0031109 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule associated complex#GO:0005875;microtubule organizing center#GO:0005815;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000008602.3|UniProtKB=F6TPD4 F6TPD4 PTHR18966:SF422 IONOTROPIC GLUTAMATE RECEPTOR GLUTAMATE RECEPTOR 1-RELATED signaling receptor activity#GO:0038023;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;molecular transducer activity#GO:0060089;ligand-gated monoatomic ion channel activity#GO:0015276;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267;monoatomic ion channel activity#GO:0005216;ligand-gated channel activity#GO:0022834 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Ionotropic glutamate receptor pathway#P00037>Glu1#P01018;Metabotropic glutamate receptor group III pathway#P00039>A/K#P01046;Ionotropic glutamate receptor pathway#P00037>A/K#P01025;Ionotropic glutamate receptor pathway#P00037>AMPA#P01019 CIOIN|Ensembl=ENSCING00000007247.3|UniProtKB=F6VJT7 F6VJT7 PTHR11654:SF509 OLIGOPEPTIDE TRANSPORTER-RELATED SOLUTE CARRIER FAMILY 15 MEMBER 4 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 localization#GO:0051179;establishment of localization#GO:0051234;cellular process#GO:0009987;transmembrane transport#GO:0055085;transport#GO:0006810 cellular anatomical entity#GO:0110165;membrane#GO:0016020 transporter#PC00227 CIOIN|Ensembl=ENSCING00000013977.2|UniProtKB=F6RJ04 F6RJ04 PTHR11106:SF27 GANGLIOSIDE INDUCED DIFFERENTIATION ASSOCIATED PROTEIN 2-RELATED MACRO DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000004750.3|UniProtKB=F6PRI1 F6PRI1 LOC100183486 PTHR24246:SF27 OLFACTORY RECEPTOR AND ADENOSINE RECEPTOR ADENOSINE RECEPTOR, ISOFORM A G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711 CIOIN|Ensembl=ENSCING00000018856.1|UniProtKB=F6WJM1 F6WJM1 PTHR17616:SF8 YES-ASSOCIATED PROTEIN YAP1 FAMILY MEMBER TRANSCRIPTIONAL COACTIVATOR YORKIE transcription coactivator activity#GO:0003713;molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;protein-macromolecule adaptor activity#GO:0030674 positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;intracellular signal transduction#GO:0035556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;signaling#GO:0023052;cellular response to stimulus#GO:0051716;regulation of DNA-templated transcription#GO:0006355;cell communication#GO:0007154;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA metabolic process#GO:0051252;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;hippo signaling#GO:0035329;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;positive regulation of RNA metabolic process#GO:0051254;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transcription cofactor#PC00217 CIOIN|Ensembl=ENSCING00000017626.2|UniProtKB=F6ZEU6 F6ZEU6 PTHR14324:SF3 CONDENSIN-2 COMPLEX SUBUNIT H2 CONDENSIN-2 COMPLEX SUBUNIT H2 protein-containing complex binding#GO:0044877;binding#GO:0005488;chromatin binding#GO:0003682 nuclear chromosome segregation#GO:0098813;chromosome separation#GO:0051304;mitotic sister chromatid separation#GO:0051306;sister chromatid segregation#GO:0000819;meiotic cell cycle#GO:0051321;nuclear division#GO:0000280;cell cycle process#GO:0022402;chromosome condensation#GO:0030261;cellular component organization#GO:0016043;cellular process#GO:0009987;mitotic cell cycle process#GO:1903047;chromosome segregation#GO:0007059;cellular component organization or biogenesis#GO:0071840;chromosome organization involved in meiotic cell cycle#GO:0070192;mitotic cell cycle#GO:0000278;reproduction#GO:0000003;organelle organization#GO:0006996;chromosome organization#GO:0051276;meiotic cell cycle process#GO:1903046;sexual reproduction#GO:0019953;reproductive process#GO:0022414;cell cycle#GO:0007049;mitotic nuclear division#GO:0140014;organelle fission#GO:0048285;mitotic sister chromatid segregation#GO:0000070 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000024609.1|UniProtKB=H2XP52 H2XP52 PTHR24067:SF157 UBIQUITIN-CONJUGATING ENZYME E2 FI11905P ubiquitin-like protein conjugating enzyme activity#GO:0061650;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin conjugating enzyme activity#GO:0061631;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;protein polyubiquitination#GO:0000209;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000007304.3|UniProtKB=F6S765 F6S765 PTHR34105:SF1 PROLINE-, GLUTAMIC ACID- AND LEUCINE-RICH PROTEIN 1 PROLINE-, GLUTAMIC ACID- AND LEUCINE-RICH PROTEIN 1 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000002691.3|UniProtKB=F6XNX8 F6XNX8 PTHR23427:SF2 SURFEIT LOCUS PROTEIN SURFEIT LOCUS PROTEIN 1 chaperone#PC00072 CIOIN|Ensembl=ENSCING00000007114.3|UniProtKB=F6SWT2 F6SWT2 LOC100176515 PTHR10579:SF172 CALCIUM-ACTIVATED CHLORIDE CHANNEL REGULATOR CALCIUM-ACTIVATED CHLORIDE CHANNEL REGULATOR 4 PRECURSOR-RELATED ion channel#PC00133;transporter#PC00227 CIOIN|Ensembl=ENSCING00000020815.1|UniProtKB=F6VJQ1 F6VJQ1 PTHR10666:SF458 UBIQUITIN POLYUBIQUITIN-C nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159;ubiquitin-like protein ligase binding#GO:0044389;protein binding#GO:0005515;enzyme binding#GO:0019899;ubiquitin protein ligase binding#GO:0031625 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;protein modification by small protein conjugation#GO:0032446;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000007294.3|UniProtKB=F6Z3S0 F6Z3S0 PTHR11956:SF5 ARGINYL-TRNA SYNTHETASE ARGININE--TRNA LIGASE, CYTOPLASMIC catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;ligase activity#GO:0016874;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;peptide biosynthetic process#GO:0043043;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 aminoacyl-tRNA synthetase#PC00047;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000022383.1|UniProtKB=H2XPF4 H2XPF4 PTHR10984:SF30 ENDOPLASMIC RETICULUM-GOLGI INTERMEDIATE COMPARTMENT PROTEIN ENDOPLASMIC RETICULUM-GOLGI INTERMEDIATE COMPARTMENT PROTEIN 2 localization#GO:0051179;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;establishment of localization#GO:0051234;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;transport#GO:0006810;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193 cytoplasm#GO:0005737;COPII-coated ER to Golgi transport vesicle#GO:0030134;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cellular anatomical entity#GO:0110165;organelle#GO:0043226;coated vesicle#GO:0030135;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000007408.3|UniProtKB=F6W3N0 F6W3N0 PTHR43763:SF6 XAA-PRO AMINOPEPTIDASE 1 XAA-PRO AMINOPEPTIDASE 1 protease#PC00190 CIOIN|Ensembl=ENSCING00000009567.3|UniProtKB=F6TK16 F6TK16 LOC100176329 PTHR43899:SF13 RH59310P RH59310P oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 CIOIN|Ensembl=ENSCING00000001414.3|UniProtKB=F6ZA70 F6ZA70 PTHR31395:SF23 SHISA GEO05642P1 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000024331.1|UniProtKB=H2Y125 H2Y125 PTHR36978:SF4 P-LOOP CONTAINING NUCLEOTIDE TRIPHOSPHATE HYDROLASE P-LOOP CONTAINING NUCLEOSIDE TRIPHOSPHATE HYDROLASE PROTEIN metabolite interconversion enzyme#PC00262;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000000424.3|UniProtKB=F7BKQ3 F7BKQ3 PTHR14167:SF116 SH3 DOMAIN-CONTAINING CAP, ISOFORM AC scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000003622.3|UniProtKB=F6U8B5 F6U8B5 LOC100186604 PTHR10285:SF70 URIDINE KINASE URIDINE KINASE cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 nucleotide kinase#PC00172 Salvage pyrimidine ribonucleotides#P02775>Uridine kinase#P03150;Salvage pyrimidine ribonucleotides#P02775>Cytidine kinase#P03149;Salvage pyrimidine ribonucleotides#P02775>CDP kinase#P03156 CIOIN|Ensembl=ENSCING00000009053.3|UniProtKB=F6R2K7 F6R2K7 LOC100180725 PTHR13337:SF2 SUCCINATE DEHYDROGENASE SUCCINATE DEHYDROGENASE [UBIQUINONE] CYTOCHROME B SMALL SUBUNIT, MITOCHONDRIAL tetrapyrrole binding#GO:0046906;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;heme binding#GO:0020037 aerobic respiration#GO:0009060;cellular respiration#GO:0045333;aerobic electron transport chain#GO:0019646;generation of precursor metabolites and energy#GO:0006091;electron transport chain#GO:0022900;ATP synthesis coupled electron transport#GO:0042773;cellular metabolic process#GO:0044237;cellular process#GO:0009987;energy derivation by oxidation of organic compounds#GO:0015980;tricarboxylic acid cycle#GO:0006099;primary metabolic process#GO:0044238;mitochondrial ATP synthesis coupled electron transport#GO:0042775;respiratory electron transport chain#GO:0022904;oxidative phosphorylation#GO:0006119;mitochondrial electron transport, succinate to ubiquinone#GO:0006121;metabolic process#GO:0008152 envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;respiratory chain complex#GO:0098803;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;oxidoreductase complex#GO:1990204;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;respirasome#GO:0070469;protein-containing complex#GO:0032991;mitochondrial envelope#GO:0005740;mitochondrial respirasome#GO:0005746;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227;mitochondrial protein-containing complex#GO:0098798 oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000008425.3|UniProtKB=F6QPY3 F6QPY3 PTHR11474:SF126 TYROSINASE FAMILY MEMBER TYROSINASE-LIKE PROTEIN TYR-1-RELATED oxygenase#PC00177;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000012762.2|UniProtKB=F6ZQD4 F6ZQD4 PTHR12369:SF11 CHONDROITIN SYNTHASE HEXOSYLTRANSFERASE transferase activity#GO:0016740;catalytic activity#GO:0003824;glycosyltransferase activity#GO:0016757;hexosyltransferase activity#GO:0016758;UDP-glycosyltransferase activity#GO:0008194 glycosyltransferase#PC00111 CIOIN|Ensembl=ENSCING00000020004.1|UniProtKB=H2XPR3 H2XPR3 PTHR11388:SF157 ORGANIC ANION TRANSPORTER SOLUTE CARRIER ORGANIC ANION TRANSPORTER FAMILY MEMBER 2A1-LIKE secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 localization#GO:0051179;organic substance transport#GO:0071702;establishment of localization#GO:0051234;organic anion transport#GO:0015711;transport#GO:0006810 basal plasma membrane#GO:0009925;basolateral plasma membrane#GO:0016323;plasma membrane region#GO:0098590;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;basal part of cell#GO:0045178;plasma membrane#GO:0005886 transporter#PC00227 CIOIN|Ensembl=ENSCING00000009266.3|UniProtKB=D2KU21 D2KU21 Ci-GlyR PTHR18945:SF898 NEUROTRANSMITTER GATED ION CHANNEL GLUTAMATE-GATED CHLORIDE CHANNEL inorganic molecular entity transmembrane transporter activity#GO:0015318;chloride channel activity#GO:0005254;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;chloride transmembrane transporter activity#GO:0015108;ligand-gated monoatomic ion channel activity#GO:0015276;channel activity#GO:0015267;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic anion transmembrane transporter activity#GO:0008509;inorganic anion transmembrane transporter activity#GO:0015103;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;ligand-gated channel activity#GO:0022834 localization#GO:0051179;inorganic anion transmembrane transport#GO:0098661;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic anion transmembrane transport#GO:0098656;monoatomic ion transmembrane transport#GO:0034220;transport#GO:0006810;monoatomic anion transport#GO:0006820;chloride transport#GO:0006821;chloride transmembrane transport#GO:1902476;inorganic ion transmembrane transport#GO:0098660;monoatomic ion transport#GO:0006811;cellular process#GO:0009987;inorganic anion transport#GO:0015698 ligand-gated ion channel#PC00141;ion channel#PC00133;transporter#PC00227 CIOIN|Ensembl=ENSCING00000008930.3|UniProtKB=F6QA51 F6QA51 PTHR19290:SF164 BASIC HELIX-LOOP-HELIX PROTEIN NEUROGENIN-RELATED BHLH DOMAIN-CONTAINING PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of nitrogen compound metabolic process#GO:0051173;neurogenesis#GO:0022008;positive regulation of RNA biosynthetic process#GO:1902680;cell projection organization#GO:0030030;regulation of nitrogen compound metabolic process#GO:0051171;animal organ development#GO:0048513;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;neuron differentiation#GO:0030182;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;multicellular organism development#GO:0007275;cellular component organization#GO:0016043;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;anatomical structure development#GO:0048856;biological regulation#GO:0065007;neuron development#GO:0048666;multicellular organismal process#GO:0032501;positive regulation of RNA metabolic process#GO:0051254;generation of neurons#GO:0048699;sensory organ development#GO:0007423;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;basic helix-loop-helix transcription factor#PC00055 CIOIN|Ensembl=ENSCING00000005631.3|UniProtKB=F7A9K4 F7A9K4 tektinA1 PTHR19960:SF12 TEKTIN TEKTIN-4 cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cell projection organization#GO:0030030;microtubule-based movement#GO:0007018;cilium or flagellum-dependent cell motility#GO:0001539;cell motility#GO:0048870;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031;cilium movement involved in cell motility#GO:0060294;cilium movement#GO:0003341;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cilium-dependent cell motility#GO:0060285;microtubule-based process#GO:0007017;organelle organization#GO:0006996;plasma membrane bounded cell projection assembly#GO:0120031 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 CIOIN|Ensembl=ENSCING00000001450.3|UniProtKB=F6VL21 F6VL21 PTHR24355:SF18 G PROTEIN-COUPLED RECEPTOR KINASE/RIBOSOMAL PROTEIN S6 KINASE G PROTEIN-COUPLED RECEPTOR KINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;phosphorylation#GO:0016310;protein phosphorylation#GO:0006468;cellular process#GO:0009987;protein metabolic process#GO:0019538;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GPRK#P00741;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>GRK3#P05941;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GPRK#P00701;Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Rhodopsin kinase#P00750;Parkinson disease#P00049>GRK#P01234 CIOIN|Ensembl=ENSCING00000003809.3|UniProtKB=F7AB81 F7AB81 LOC100182088 PTHR10159:SF529 DUAL SPECIFICITY PROTEIN PHOSPHATASE TYROSINE-PROTEIN PHOSPHATASE DOMAIN-CONTAINING PROTEIN hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 regulation of MAPK cascade#GO:0043408;negative regulation of biological process#GO:0048519;macromolecule modification#GO:0043412;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;protein modification process#GO:0036211;regulation of intracellular signal transduction#GO:1902531;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;negative regulation of MAPK cascade#GO:0043409;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of cell communication#GO:0010646;negative regulation of response to stimulus#GO:0048585;macromolecule metabolic process#GO:0043170;negative regulation of signaling#GO:0023057;cellular metabolic process#GO:0044237;protein dephosphorylation#GO:0006470;organonitrogen compound metabolic process#GO:1901564;cellular process#GO:0009987;primary metabolic process#GO:0044238;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;dephosphorylation#GO:0016311;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 protein phosphatase#PC00195;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000006888.3|UniProtKB=F6YTX7 F6YTX7 zf(c3h)-2 PTHR12681:SF0 ZINC FINGER-CONTAINING PROTEIN P48ZNF ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 15 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cytoplasmic translation#GO:0002181;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 zinc finger transcription factor#PC00244 CIOIN|Ensembl=ENSCING00000020814.1|UniProtKB=H2Y104 H2Y104 LOC100185112 PTHR14969:SF13 SPHINGOSINE-1-PHOSPHATE PHOSPHOHYDROLASE AT30094P metabolite interconversion enzyme#PC00262;hydrolase#PC00121;phosphatase#PC00181 CIOIN|Ensembl=ENSCING00000006897.3|UniProtKB=H2XSK1 H2XSK1 PTHR23117:SF13 GUANYLATE KINASE-RELATED GUANYLATE KINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, phosphate group as acceptor#GO:0016776;catalytic activity#GO:0003824;kinase activity#GO:0016301 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 transferase#PC00220;kinase#PC00137;metabolite interconversion enzyme#PC00262 De novo purine biosynthesis#P02738>Guanylate kinase#P02904 CIOIN|Ensembl=ENSCING00000021894.1|UniProtKB=H2XTD3 H2XTD3 PTHR19325:SF567 COMPLEMENT COMPONENT-RELATED SUSHI DOMAIN-CONTAINING SUSHI, VON WILLEBRAND FACTOR TYPE A, EGF AND PENTRAXIN DOMAIN-CONTAINING PROTEIN 1-LIKE complement component#PC00078 CIOIN|Ensembl=ENSCING00000004877.3|UniProtKB=A0A1W5BDS1 A0A1W5BDS1 LOC100185146 PTHR45894:SF1 RNA-BINDING PROTEIN 8A RNA-BINDING PROTEIN 8A nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Gene=nvd-Ci-1|UniProtKB=F7J186 F7J186 nvd-Ci-1 PTHR21266:SF32 IRON-SULFUR DOMAIN CONTAINING PROTEIN CHOLESTEROL 7-DESATURASE NVD oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 oxygenase#PC00177;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000005955.3|UniProtKB=F6WFD1 F6WFD1 LOC100178614 PTHR10528:SF17 AF4/FMR2 FAMILY MEMBER AF4_FMR2 FAMILY MEMBER LILLI regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of biosynthetic process#GO:0009889;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;transcription elongation factor complex#GO:0008023;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218 CIOIN|Ensembl=ENSCING00000023741.1|UniProtKB=H2XQI3 H2XQI3 PTHR11214:SF283 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE N-ACETYLLACTOSAMINIDE BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE 4-LIKE transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;protein O-linked glycosylation#GO:0006493;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 bounding membrane of organelle#GO:0098588;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;Golgi membrane#GO:0000139;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111 CIOIN|Ensembl=ENSCING00000001628.3|UniProtKB=F7B8G2 F7B8G2 PTHR10130:SF0 PEROXISOMAL TARGETING SIGNAL 1 RECEPTOR PEX5 GH08708P signal sequence binding#GO:0005048;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277 cellular localization#GO:0051641;intracellular protein transmembrane transport#GO:0065002;transmembrane transport#GO:0055085;macromolecule localization#GO:0033036;protein import into peroxisome matrix#GO:0016558;transport#GO:0006810;protein transmembrane transport#GO:0071806;nitrogen compound transport#GO:0071705;establishment of protein localization to organelle#GO:0072594;cellular component organization#GO:0016043;cellular process#GO:0009987;protein transmembrane import into intracellular organelle#GO:0044743;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;organelle organization#GO:0006996;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;protein localization to organelle#GO:0033365;peroxisome organization#GO:0007031 bounding membrane of organelle#GO:0098588;peroxisomal membrane#GO:0005778;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;peroxisome#GO:0005777;microbody#GO:0042579;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 membrane trafficking regulatory protein#PC00151 CIOIN|Ensembl=ENSCING00000000919.3|UniProtKB=F7APS6 F7APS6 PTHR11098:SF1 NICOTINATE PHOSPHORIBOSYLTRANSFERASE NICOTINATE PHOSPHORIBOSYLTRANSFERASE ligase activity#GO:0016874;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;pyridine nucleotide metabolic process#GO:0019362;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;nucleotide biosynthetic process#GO:0009165;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;pyridine-containing compound metabolic process#GO:0072524;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;nicotinamide nucleotide metabolic process#GO:0046496;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111 CIOIN|Ensembl=ENSCING00000003209.3|UniProtKB=F6S2V8 F6S2V8 coe PTHR10747:SF38 TRANSCRIPTION FACTOR COE FAMILY MEMBER TRANSCRIPTION FACTOR COLLIER sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 P53-like transcription factor#PC00253;immunoglobulin fold transcription factor#PC00251 CIOIN|Ensembl=ENSCING00000012789.2|UniProtKB=F6XC87 F6XC87 PTHR46015:SF1 ZGC:172121 HOMOCYSTEINE S-METHYLTRANSFERASE-LIKE ISOFORM 1 methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757 organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;proteinogenic amino acid metabolic process#GO:0170039;sulfur compound metabolic process#GO:0006790;proteinogenic amino acid biosynthetic process#GO:0170038;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;aspartate family amino acid biosynthetic process#GO:0009067;alpha-amino acid biosynthetic process#GO:1901607;nitrogen compound metabolic process#GO:0006807;cellular modified amino acid metabolic process#GO:0006575;amino acid biosynthetic process#GO:0008652;alpha-amino acid metabolic process#GO:1901605;aspartate family amino acid metabolic process#GO:0009066;small molecule biosynthetic process#GO:0044283;L-amino acid biosynthetic process#GO:0170034;carboxylic acid metabolic process#GO:0019752;L-amino acid metabolic process#GO:0170033;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 Methionine biosynthesis#P02753>Homocysteine transmethylase#P03024;Formyltetrahydrofolate biosynthesis#P02743>Cobalamin dependent homocysteine transmethylase#P02953 CIOIN|Ensembl=ENSCING00000009341.3|UniProtKB=F6Z3Z5 F6Z3Z5 LOC100187183 PTHR10689:SF6 MICROSOMAL GLUTATHIONE S-TRANSFERASE 1 MICROSOMAL GLUTATHIONE S-TRANSFERASE 1 transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000004251.3|UniProtKB=F6TDN1 F6TDN1 PTHR13318:SF152 PARTNER OF PAIRED, ISOFORM B-RELATED F-BOX_LRR-REPEAT PROTEIN 4 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 SCF ubiquitin ligase complex#GO:0019005;intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;cullin-RING ubiquitin ligase complex#GO:0031461;transferase complex#GO:1990234 CIOIN|Ensembl=ENSCING00000018842.1|UniProtKB=H2XT10 H2XT10 LOC100178871 PTHR31698:SF7 LYSOZYME G FAMILY MEMBER PEPTIDASE M15C DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000005769.3|UniProtKB=F6RT01 F6RT01 PTHR10851:SF0 PYRIDOXINE-5-PHOSPHATE OXIDASE PYRIDOXINE-5'-PHOSPHATE OXIDASE oxidase#PC00175;oxidoreductase#PC00176 Pyridoxal-5-phosphate biosynthesis#P02759>Pyridoxine-5-phosphate oxidase#P03061;Pyridoxal phosphate salvage pathway#P02770>Pyridoxine-5-phosphate oxidase#P03123;Vitamin B6 metabolism#P02787>Pyridoxamine phosphate oxidase#P03236;Pyridoxal phosphate salvage pathway#P02770>Pyridoxamine-5-phosphate oxidase#P03120 CIOIN|Ensembl=ENSCING00000005018.3|UniProtKB=F6TXK0 F6TXK0 PTHR16320:SF1 SPHINGOMYELINASE FAMILY MEMBER SPHINGOMYELINASE DDB_G0288017 hydrolase activity#GO:0016787;lipase activity#GO:0016298;hydrolase activity, acting on ester bonds#GO:0016788;phospholipase activity#GO:0004620;catalytic activity#GO:0003824 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000009146.3|UniProtKB=H2XNY4 H2XNY4 PTHR15970:SF2 ELL-ASSOCIATED FACTOR EAF ELL-ASSOCIATED FACTOR EAF transcription regulator activity#GO:0140110 cellular aromatic compound metabolic process#GO:0006725;DNA-templated transcription#GO:0006351;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;DNA-templated transcription elongation#GO:0006354;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;RNA biosynthetic process#GO:0032774;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nucleobase-containing compound biosynthetic process#GO:0034654;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;aromatic compound biosynthetic process#GO:0019438;transcription elongation by RNA polymerase II#GO:0006368;transcription by RNA polymerase II#GO:0006366;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;transcription elongation factor complex#GO:0008023;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000008358.3|UniProtKB=F7AK22 F7AK22 PTHR20961:SF148 GLYCOSYLTRANSFERASE EGF DOMAIN-SPECIFIC O-LINKED N-ACETYLGLUCOSAMINE TRANSFERASE transferase activity#GO:0016740;catalytic activity#GO:0003824;glycosyltransferase activity#GO:0016757 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000006508.3|UniProtKB=F6THY1 F6THY1 PTHR12098:SF2 E3 UBIQUITIN-PROTEIN LIGASE PELLINO-RELATED PROTEIN PELLINO transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein polyubiquitination#GO:0000209;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000005979.3|UniProtKB=F6VTD9 F6VTD9 PTHR43329:SF141 EPOXIDE HYDROLASE AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN-RELATED hydrolase activity#GO:0016787;catalytic activity#GO:0003824 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000021628.1|UniProtKB=H2Y2N8 H2Y2N8 PTHR24044:SF511 NOTCH LIGAND FAMILY MEMBER EGF-LIKE DOMAIN-CONTAINING PROTEIN protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 intercellular signal molecule#PC00207 CIOIN|Ensembl=ENSCING00000008559.3|UniProtKB=F6XP19 F6XP19 PTHR24256:SF545 TRYPTASE-RELATED INACTIVE SERINE PROTEASE 54 hydrolase activity#GO:0016787;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 serine protease#PC00203;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000003845.3|UniProtKB=F6YPZ5 F6YPZ5 PTHR11616:SF289 SODIUM/CHLORIDE DEPENDENT TRANSPORTER TRANSPORTER secondary active monocarboxylate transmembrane transporter activity#GO:0015355;inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;organic acid:sodium symporter activity#GO:0005343;organic acid transmembrane transporter activity#GO:0005342;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;chloride transmembrane transporter activity#GO:0015108;organic anion transmembrane transporter activity#GO:0008514;monoatomic cation transmembrane transporter activity#GO:0008324;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;amino acid:sodium symporter activity#GO:0005283;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;metal ion transmembrane transporter activity#GO:0046873;active monoatomic ion transmembrane transporter activity#GO:0022853;monoatomic anion transmembrane transporter activity#GO:0008509;monocarboxylic acid transmembrane transporter activity#GO:0008028;amino acid transmembrane transporter activity#GO:0015171;inorganic anion transmembrane transporter activity#GO:0015103;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;organic anion transport#GO:0015711;amino acid transport#GO:0006865;organic acid transport#GO:0015849;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;localization#GO:0051179;organic substance transport#GO:0071702;sodium ion transport#GO:0006814;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;sodium ion transmembrane transport#GO:0035725 cell projection#GO:0042995;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 primary active transporter#PC00068;transporter#PC00227 CIOIN|Ensembl=ENSCING00000001634.3|UniProtKB=F6YS92 F6YS92 LOC100185786 PTHR13327:SF0 NADH-UBIQUINONE OXIDOREDUCTASE ESSS SUBUNIT, MITOCHONDRIAL PRECURSOR NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 11, MITOCHONDRIAL envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;respiratory chain complex#GO:0098803;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transporter complex#GO:1990351;oxidoreductase complex#GO:1990204;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;respirasome#GO:0070469;mitochondrial respiratory chain complex I#GO:0005747;protein-containing complex#GO:0032991;mitochondrial envelope#GO:0005740;inner mitochondrial membrane protein complex#GO:0098800;transmembrane transporter complex#GO:1902495;mitochondrial respirasome#GO:0005746;membrane-bounded organelle#GO:0043227;respiratory chain complex I#GO:0045271;NADH dehydrogenase complex#GO:0030964;mitochondrial protein-containing complex#GO:0098798 oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000019887.1|UniProtKB=Q1RL78 Q1RL78 Ci-ZF(C2H2)-135 PTHR24406:SF8 TRANSCRIPTIONAL REPRESSOR CTCFL-RELATED FI01110P-RELATED nucleic acid binding#GO:0003676;protein-containing complex binding#GO:0044877;chromatin DNA binding#GO:0031490;binding#GO:0005488;organic cyclic compound binding#GO:0097159;chromatin binding#GO:0003682;DNA binding#GO:0003677 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;chromosome#GO:0005694;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 CIOIN|Ensembl=ENSCING00000007680.3|UniProtKB=F6Z9D3 F6Z9D3 cam-k PTHR24347:SF412 SERINE/THREONINE-PROTEIN KINASE SERINE_THREONINE-PROTEIN KINASE H1 HOMOLOG-RELATED non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CaMK#P00847;Ionotropic glutamate receptor pathway#P00037>CaMKII#P01023 CIOIN|Ensembl=ENSCING00000003335.3|UniProtKB=F7A4L3 F7A4L3 PTHR42686:SF1 GH17980P-RELATED GH17980P-RELATED oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 reductase#PC00198;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000008777.3|UniProtKB=F6R0S4 F6R0S4 PTHR11937:SF571 ACTIN ACTIN, CYTOSKELETAL 1B actin and actin related protein#PC00039;cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 Integrin signalling pathway#P00034>Actin#P00944;Alzheimer disease-presenilin pathway#P00004>actin#P00114;Nicotinic acetylcholine receptor signaling pathway#P00044>Actin#P01090;Huntington disease#P00029>Actin#P00807;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>F-actin#P00858;Cadherin signaling pathway#P00012>F-actin#P00470;Cytoskeletal regulation by Rho GTPase#P00016>Actin#P00512 CIOIN|Ensembl=ENSCING00000024953.1|UniProtKB=H2XWY6 H2XWY6 LOC113474038 PTHR43591:SF101 METHYLTRANSFERASE METHYLTRANSFERASE-LIKE PROTEIN 27 methyltransferase#PC00155;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000005967.3|UniProtKB=F6VTZ3 F6VTZ3 PTHR12169:SF6 ATPASE N2B AFG1-LIKE ATPASE pyrophosphatase activity#GO:0016462;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;ATP hydrolysis activity#GO:0016887 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000016495.2|UniProtKB=F6YMT8 F6YMT8 LOC100179414 PTHR13121:SF0 GPI TRANSAMIDASE COMPONENT PIG-U PHOSPHATIDYLINOSITOL GLYCAN ANCHOR BIOSYNTHESIS CLASS U PROTEIN lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;phospholipid biosynthetic process#GO:0008654;macromolecule modification#GO:0043412;phosphatidylinositol biosynthetic process#GO:0006661;organophosphate biosynthetic process#GO:0090407;glycolipid metabolic process#GO:0006664;protein modification process#GO:0036211;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;lipid biosynthetic process#GO:0008610;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;protein lipidation#GO:0006497;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;glycerolipid biosynthetic process#GO:0045017;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;glycerophospholipid metabolic process#GO:0006650;phosphatidylinositol metabolic process#GO:0046488;organic substance biosynthetic process#GO:1901576;liposaccharide metabolic process#GO:1903509;cellular process#GO:0009987;membrane lipid biosynthetic process#GO:0046467;GPI anchor metabolic process#GO:0006505;lipoprotein biosynthetic process#GO:0042158;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;GPI anchor biosynthetic process#GO:0006506;membrane lipid metabolic process#GO:0006643;glycerophospholipid biosynthetic process#GO:0046474;glycolipid biosynthetic process#GO:0009247;organophosphate metabolic process#GO:0019637;lipoprotein metabolic process#GO:0042157;cellular lipid metabolic process#GO:0044255 membrane protein complex#GO:0098796;peptidase complex#GO:1905368;endoplasmic reticulum protein-containing complex#GO:0140534;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;endopeptidase complex#GO:1905369;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 CIOIN|Ensembl=ENSCING00000014059.2|UniProtKB=F6QP88 F6QP88 LOC100182013 PTHR46708:SF9 TENASCIN FIBRONECTIN extracellular matrix protein#PC00102 CIOIN|Ensembl=ENSCING00000004774.3|UniProtKB=F6PLY6 F6PLY6 LOC100184256 PTHR11097:SF8 EXOSOME COMPLEX EXONUCLEASE RIBOSOMAL RNA PROCESSING PROTEIN EXOSOME COMPLEX COMPONENT RRP42 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159;mRNA 3'-UTR binding#GO:0003730 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;heterocycle catabolic process#GO:0046700;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular nitrogen compound catabolic process#GO:0044270;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;organic cyclic compound metabolic process#GO:1901360;rRNA metabolic process#GO:0016072;nitrogen compound metabolic process#GO:0006807;organic cyclic compound catabolic process#GO:1901361;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;organic substance catabolic process#GO:1901575;nucleobase-containing compound catabolic process#GO:0034655;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;exosome (RNase complex)#GO:0000178;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031;exoribonuclease#PC00099 CIOIN|Ensembl=ENSCING00000023269.1|UniProtKB=H2XZ67 H2XZ67 PTHR12292:SF2 RWD DOMAIN-CONTAINING PROTEIN RWD DOMAIN-CONTAINING PROTEIN 1 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cytoplasmic translation#GO:0002181;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;translation#GO:0006412;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 CIOIN|Ensembl=ENSCING00000008887.3|UniProtKB=F6QX88 F6QX88 LOC100176974 PTHR31432:SF0 INTRAFLAGELLAR TRANSPORT PROTEIN 74 HOMOLOG INTRAFLAGELLAR TRANSPORT PROTEIN 74 HOMOLOG cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;cilium assembly#GO:0060271;cell projection organization#GO:0030030;transport#GO:0006810;microtubule-based movement#GO:0007018;cellular component organization#GO:0016043;intraciliary transport involved in cilium assembly#GO:0035735;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;transport along microtubule#GO:0010970;cell projection assembly#GO:0030031;intraciliary transport#GO:0042073;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based transport#GO:0099111;microtubule-based process#GO:0007017;establishment of localization#GO:0051234;organelle organization#GO:0006996;cytoskeleton-dependent intracellular transport#GO:0030705;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;protein-containing complex localization#GO:0031503 protein-containing complex#GO:0032991;intraciliary transport particle B#GO:0030992;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cilium#GO:0005929;intraciliary transport particle#GO:0030990 CIOIN|Ensembl=ENSCING00000006487.2|UniProtKB=F6Q1U9 F6Q1U9 PTHR22802:SF455 C-TYPE LECTIN SUPERFAMILY MEMBER C-TYPE LECTIN DOMAIN FAMILY 4 MEMBER F-LIKE membrane traffic protein#PC00150 CIOIN|Ensembl=ENSCING00000014662.1|UniProtKB=F7BHV9 F7BHV9 PTHR31139:SF6 ECTOPIC P GRANULES PROTEIN 5 HOMOLOG PROTEIN LIMB EXPRESSION 1 HOMOLOG process utilizing autophagic mechanism#GO:0061919;cellular component organization or biogenesis#GO:0071840;cellular component disassembly#GO:0022411;protein-containing complex disassembly#GO:0032984;macroautophagy#GO:0016236;protein-containing complex organization#GO:0043933;catabolic process#GO:0009056;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;autophagosome maturation#GO:0097352;cellular process#GO:0009987;autophagy#GO:0006914;cellular catabolic process#GO:0044248;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000008614.3|UniProtKB=F6T2D0 F6T2D0 LOC100187315 PTHR28608:SF1 INTEGRATOR COMPLEX SUBUNIT 2 INTEGRATOR COMPLEX SUBUNIT 2 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;snRNA metabolic process#GO:0016073;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;snRNA 3'-end processing#GO:0034472;snRNA processing#GO:0016180;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;integrator complex#GO:0032039 CIOIN|Ensembl=ENSCING00000009000.3|UniProtKB=F6UBJ3 F6UBJ3 PTHR21646:SF23 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE USP2 cysteine protease#PC00081;protease#PC00190 CIOIN|Ensembl=ENSCING00000020221.1|UniProtKB=H2XSH1 H2XSH1 PTHR35559:SF1 CHITIN-BINDING TYPE-4 DOMAIN-CONTAINING PROTEIN CHITIN-BINDING TYPE-4 DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000008609.3|UniProtKB=F6TNW3 F6TNW3 PTHR18860:SF17 14-3-3 PROTEIN 14-3-3 PROTEIN EPSILON localization#GO:0051179;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular localization#GO:0051641;cellular response to stimulus#GO:0051716;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052;protein localization#GO:0008104 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 Parkinson disease#P00049>14-3-3#P01238;FGF signaling pathway#P00021>14-3-3#P00624;EGF receptor signaling pathway#P00018>14-3-3#P00539 CIOIN|Ensembl=ENSCING00000006612|UniProtKB=Q95YJ5 Q95YJ5 CiIC3 PTHR46135:SF3 NME/NM23 FAMILY MEMBER 8 NME_NM23 FAMILY MEMBER 8 CIOIN|Ensembl=ENSCING00000021026.1|UniProtKB=H2Y3N5 H2Y3N5 PTHR10824:SF4 ACYL-COENZYME A THIOESTERASE-RELATED ACYL-COENZYME A THIOESTERASE 1-LIKE hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;fatty acyl-CoA hydrolase activity#GO:0047617;catalytic activity#GO:0003824;thiolester hydrolase activity#GO:0016790 cellular aromatic compound metabolic process#GO:0006725;lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;amide metabolic process#GO:0043603;purine nucleotide metabolic process#GO:0006163;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;acyl-CoA metabolic process#GO:0006637;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;ribonucleotide metabolic process#GO:0009259;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;purine ribonucleotide metabolic process#GO:0009150;fatty acid metabolic process#GO:0006631;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 esterase#PC00097 CIOIN|Ensembl=ENSCING00000012119.2|UniProtKB=F6V8E3 F6V8E3 PTHR45712:SF1 AGAP008170-PA NEPHROCAN extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 CIOIN|Ensembl=ENSCING00000002711.3|UniProtKB=F6UDY1 F6UDY1 LOC100179607 PTHR12064:SF94 METAL TRANSPORTER CNNM UNEXTENDED PROTEIN ion channel#PC00133;transporter#PC00227 CIOIN|Ensembl=ENSCING00000012769.2|UniProtKB=Q1RLE5 Q1RLE5 Ci-ZF(C2H2)-86 PTHR24390:SF235 ZINC FINGER PROTEIN GH09339P-RELATED sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 CIOIN|Ensembl=ENSCING00000025107.1|UniProtKB=H2XQ66 H2XQ66 LOC100177849 PTHR13254:SF0 GOLGI AUTOANTIGEN, GOLGIN SUBFAMILY A, 7 GOLGIN SUBFAMILY A MEMBER 7_ERF4 DOMAIN-CONTAINING PROTEIN cellular localization#GO:0051641;macromolecule localization#GO:0033036;macromolecule modification#GO:0043412;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;biosynthetic process#GO:0009058;establishment of protein localization#GO:0045184;establishment of protein localization to membrane#GO:0090150;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;protein palmitoylation#GO:0018345;protein metabolic process#GO:0019538;protein lipidation#GO:0006497;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;localization within membrane#GO:0051668;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein localization to membrane#GO:0072657;organonitrogen compound biosynthetic process#GO:1901566;protein targeting#GO:0006605;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;protein acylation#GO:0043543;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;lipoprotein biosynthetic process#GO:0042158;protein localization#GO:0008104;primary metabolic process#GO:0044238;localization#GO:0051179;protein targeting to membrane#GO:0006612;cellular macromolecule localization#GO:0070727;lipoprotein metabolic process#GO:0042157 protein-containing complex#GO:0032991;catalytic complex#GO:1902494;transferase complex#GO:1990234 CIOIN|Ensembl=ENSCING00000005778.3|UniProtKB=F6RHK8 F6RHK8 LOC100181655 PTHR43866:SF3 MALONATE-SEMIALDEHYDE DEHYDROGENASE METHYLMALONATE-SEMIALDEHYDE DEHYDROGENASE [ACYLATING], MITOCHONDRIAL oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;heterocycle catabolic process#GO:0046700;branched-chain amino acid metabolic process#GO:0009081;pyrimidine-containing compound metabolic process#GO:0072527;organonitrogen compound catabolic process#GO:1901565;nucleobase metabolic process#GO:0009112;nucleobase-containing compound metabolic process#GO:0006139;cellular nitrogen compound catabolic process#GO:0044270;pyrimidine nucleobase metabolic process#GO:0006206;amino acid catabolic process#GO:0009063;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;alpha-amino acid metabolic process#GO:1901605;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;pyrimidine nucleobase catabolic process#GO:0006208;organic cyclic compound catabolic process#GO:1901361;carboxylic acid metabolic process#GO:0019752;amino acid metabolic process#GO:0006520;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 dehydrogenase#PC00092;oxidoreductase#PC00176 Pyrimidine Metabolism#P02771>Methylmalonate Semialdehyde Dehydrogenase#P03124 CIOIN|Ensembl=ENSCING00000019351.1|UniProtKB=H2XN03 H2XN03 PTHR32026:SF10 METHYLTRANSFERASE-LIKE PROTEIN 24 METHYLTRANSFERASE-LIKE PROTEIN 24-RELATED methyltransferase#PC00155 CIOIN|Ensembl=ENSCING00000013892.2|UniProtKB=F6Q1Z4 F6Q1Z4 PTHR11311:SF30 SPONDIN SPONDIN-LIKE TSP1 DOMAIN-CONTAINING PROTEIN cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actin filament-based process#GO:0030029;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987;organelle organization#GO:0006996 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 CIOIN|Ensembl=ENSCING00000024618.1|UniProtKB=H2XPZ1 H2XPZ1 PTHR11328:SF28 MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 12 localization#GO:0051179;organic substance transport#GO:0071702;establishment of localization#GO:0051234;transport#GO:0006810 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 primary active transporter#PC00068;transporter#PC00227 CIOIN|Ensembl=ENSCING00000005840.3|UniProtKB=F6V7U4 F6V7U4 LOC100184847 PTHR44086:SF14 THIOSULFATE SULFURTRANSFERASE RDL2, MITOCHONDRIAL-RELATED RHODANESE DOMAIN-CONTAINING PROTEIN thiosulfate sulfurtransferase activity#GO:0004792;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824;sulfurtransferase activity#GO:0016783 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000005804.3|UniProtKB=F6RFT0 F6RFT0 PTHR11819:SF150 SOLUTE CARRIER FAMILY 5 SODIUM_MYO-INOSITOL COTRANSPORTER inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;carbohydrate transmembrane transporter activity#GO:0015144;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;sugar transmembrane transporter activity#GO:0051119;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;active transmembrane transporter activity#GO:0022804;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;active monoatomic ion transmembrane transporter activity#GO:0022853;monoatomic ion transmembrane transporter activity#GO:0015075;inorganic cation transmembrane transporter activity#GO:0022890;solute:monoatomic cation symporter activity#GO:0015294 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000020302.1|UniProtKB=H2XYL3 H2XYL3 PTHR10266:SF3 CYTOCHROME C1 CYTOCHROME C1, HEME PROTEIN, MITOCHONDRIAL ATP synthesis#P02721>Cyt bc1#P02799;FAS signaling pathway#P00020>CytochromeC#P00620;Huntington disease#P00029>Cytochrome c#P00785 CIOIN|Ensembl=ENSCING00000018414.1|UniProtKB=H2XYB0 H2XYB0 PTHR43347:SF3 ACYL-COA SYNTHETASE ACYL-COA SYNTHETASE SHORT-CHAIN FAMILY MEMBER 3, MITOCHONDRIAL ligase#PC00142 Methylcitrate cycle#P02754>Acetyl-CoA synthetase#P03030;Acetate utilization#P02722>Acetyl-CoA synthetase#P02803 CIOIN|Ensembl=ENSCING00000021405.1|UniProtKB=F6R0D6 F6R0D6 PTHR23259:SF70 RIDDLE ACCESSORY GLAND PROTEIN ACP62F-RELATED protease inhibitor#PC00191;protein-binding activity modulator#PC00095 CIOIN|Ensembl=ENSCING00000010023.3|UniProtKB=F6QI77 F6QI77 LOC100183767 PTHR12669:SF12 EUKARYOTIC TRANSLATION INITIATION FACTOR 4E-BINDING PROTEIN EUKARYOTIC TRANSLATION INITIATION FACTOR 4E-BINDING PROTEIN translation initiation factor binding#GO:0031369;protein binding#GO:0005515;binding#GO:0005488 negative regulation of gene expression#GO:0010629;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;negative regulation of biosynthetic process#GO:0009890;regulation of amide metabolic process#GO:0034248;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;regulation of translational initiation#GO:0006446;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of translation#GO:0017148;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;post-transcriptional regulation of gene expression#GO:0010608;biological regulation#GO:0065007;regulation of translation#GO:0006417;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 translation initiation factor#PC00224;translation factor#PC00223;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000011241.2|UniProtKB=F7AY96 F7AY96 PTHR43968:SF6 FAMILY NOT NAMED GLUTATHIONE S-TRANSFERASE OMEGA cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000021725.1|UniProtKB=H2XQ22 H2XQ22 PTHR24416:SF611 TYROSINE-PROTEIN KINASE RECEPTOR TYROSINE-PROTEIN KINASE TRANSMEMBRANE RECEPTOR ROR transmembrane signal receptor#PC00197 CIOIN|Ensembl=ENSCING00000005225.3|UniProtKB=F6Z0S6 F6Z0S6 LOC100180876 PTHR31180:SF2 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 107-RELATED CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 107 supramolecular complex#GO:0099080;axoneme#GO:0005930;cytoplasmic microtubule#GO:0005881;cytoplasmic region#GO:0099568;cellular anatomical entity#GO:0110165;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;ciliary plasm#GO:0097014;plasma membrane bounded cell projection cytoplasm#GO:0032838;cytoskeleton#GO:0005856;cell projection#GO:0042995;cilium#GO:0005929;microtubule#GO:0005874;axonemal microtubule#GO:0005879 CIOIN|Ensembl=ENSCING00000003614.3|UniProtKB=F6U9C5 F6U9C5 LOC100179164 PTHR11732:SF506 ALDO/KETO REDUCTASE ALDO-KETO REDUCTASE 1B, ISOFORM C-RELATED oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 reductase#PC00198;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000007374.3|UniProtKB=F6VBT4 F6VBT4 PTHR12345:SF3 SYNTENIN RELATED PDZ DOMAIN-CONTAINING PROTEIN cytoplasm#GO:0005737;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 membrane trafficking regulatory protein#PC00151 CIOIN|Ensembl=ENSCING00000016554.2|UniProtKB=F6TXB9 F6TXB9 PTHR24418:SF447 TYROSINE-PROTEIN KINASE TYROSINE PROTEIN-KINASE SRC-1 protein tyrosine kinase activity#GO:0004713;non-membrane spanning protein tyrosine kinase activity#GO:0004715;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein binding#GO:0005515;catalytic activity, acting on a protein#GO:0140096;signaling receptor binding#GO:0005102;kinase activity#GO:0016301;protein kinase activity#GO:0004672 response to external biotic stimulus#GO:0043207;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;immune response#GO:0006955;developmental process#GO:0032502;cell communication#GO:0007154;cellular process#GO:0009987;defense response to symbiont#GO:0140546;regulation of biological process#GO:0050789;immune system process#GO:0002376;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;cell differentiation#GO:0030154;enzyme-linked receptor protein signaling pathway#GO:0007167;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological process involved in interspecies interaction between organisms#GO:0044419;biological regulation#GO:0065007;innate immune response#GO:0045087;defense response#GO:0006952;signaling#GO:0023052;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169 non-receptor tyrosine protein kinase#PC00168 Parkinson disease#P00049>Src kinase#P01230;Integrin signalling pathway#P00034>Src#P00940 CIOIN|Ensembl=ENSCING00000009327.3|UniProtKB=F6ZM86 F6ZM86 PTHR10906:SF1 SECY/SEC61-ALPHA FAMILY MEMBER DSEC61ALPHA signal sequence binding#GO:0005048;protein transmembrane transporter activity#GO:0008320;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277 localization within membrane#GO:0051668;cotranslational protein targeting to membrane#GO:0006613;cellular localization#GO:0051641;intracellular protein transmembrane transport#GO:0065002;protein localization to endoplasmic reticulum#GO:0070972;transmembrane transport#GO:0055085;macromolecule localization#GO:0033036;protein localization to membrane#GO:0072657;transport#GO:0006810;protein transmembrane transport#GO:0071806;protein targeting#GO:0006605;nitrogen compound transport#GO:0071705;protein targeting to ER#GO:0045047;establishment of protein localization to organelle#GO:0072594;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;SRP-dependent cotranslational protein targeting to membrane#GO:0006614;organic substance transport#GO:0071702;establishment of protein localization to membrane#GO:0090150;protein targeting to membrane#GO:0006612;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;protein localization to organelle#GO:0033365;establishment of protein localization to endoplasmic reticulum#GO:0072599 transporter#PC00227 CIOIN|Ensembl=ENSCING00000011761.2|UniProtKB=F6WBG2 F6WBG2 PTHR12270:SF25 GLYCOSYLTRANSFERASE-RELATED GLYCOSYLTRANSFERASE-LIKE PROTEIN LARGE glucuronosyltransferase activity#GO:0015020;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194;pentosyltransferase activity#GO:0016763;xylosyltransferase activity#GO:0042285;hexosyltransferase activity#GO:0016758 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;protein O-linked glycosylation#GO:0006493;protein O-linked mannosylation#GO:0035269;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;protein mannosylation#GO:0035268;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085;mannosylation#GO:0097502 glycosyltransferase#PC00111 CIOIN|Ensembl=ENSCING00000008148.3|UniProtKB=F6VFZ2 F6VFZ2 LOC100183363 PTHR47992:SF63 PROTEIN PHOSPHATASE ALPHABET, ISOFORM E protein phosphatase#PC00195;protein modifying enzyme#PC00260 DPP-SCW signaling pathway#P06212>PPM1A#P06261;Activin beta signaling pathway#P06210>PPM1A#P06237;MYO signaling pathway#P06215>PPM1A#P06317;BMP/activin signaling pathway-drosophila#P06211>PPM1A#P06247;ALP23B signaling pathway#P06209>PPM1A#P06226;GBB signaling pathway#P06214>PPM1A#P06296;DPP signaling pathway#P06213>PPM1A#P06289;SCW signaling pathway#P06216>PPM1A#P06332 CIOIN|Ensembl=ENSCING00000023481.1|UniProtKB=H2XKW3 H2XKW3 PTHR22802:SF379 C-TYPE LECTIN SUPERFAMILY MEMBER CHONDROITIN SULFATE PROTEOGLYCAN 2 ISOFORM X1 membrane traffic protein#PC00150 CIOIN|Ensembl=ENSCING00000003100.3|UniProtKB=F6PK80 F6PK80 PTHR42790:SF19 AMINOTRANSFERASE KYNURENINE_ALPHA-AMINOADIPATE AMINOTRANSFERASE, MITOCHONDRIAL transaminase activity#GO:0008483;transferase activity#GO:0016740;catalytic activity#GO:0003824 oxoacid metabolic process#GO:0043436;nitrogen compound metabolic process#GO:0006807;alpha-amino acid metabolic process#GO:1901605;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;carboxylic acid metabolic process#GO:0019752;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 transaminase#PC00216 CIOIN|Ensembl=ENSCING00000006633.3|UniProtKB=F6U1G1 F6U1G1 LOC100182436 PTHR43170:SF5 GMP REDUCTASE GMP REDUCTASE reductase#PC00198;oxidoreductase#PC00176 De novo purine biosynthesis#P02738>IMP dehydrogenase#P02895 CIOIN|Ensembl=ENSCING00000006611.3|UniProtKB=F6QPQ3 F6QPQ3 PTHR13439:SF4 CT120 PROTEIN TLC DOMAIN-CONTAINING PROTEIN cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;membrane assembly#GO:0071709;regulation of biological quality#GO:0065008;membrane organization#GO:0061024;plasma membrane organization#GO:0007009;biological regulation#GO:0065007;lipid homeostasis#GO:0055088;endomembrane system organization#GO:0010256;homeostatic process#GO:0042592;cellular component organization#GO:0016043;regulation of membrane lipid distribution#GO:0097035;chemical homeostasis#GO:0048878;cellular process#GO:0009987 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000003872.3|UniProtKB=F6XGT9 F6XGT9 PTHR15092:SF37 POLY A -SPECIFIC RIBONUCLEASE/TARGET OF EGR1, MEMBER 1 TARGET OF EGR1 PROTEIN 1 hydrolase activity, acting on ester bonds#GO:0016788;nucleic acid binding#GO:0003676;nuclease activity#GO:0004518;binding#GO:0005488;catalytic activity#GO:0003824;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters#GO:0016796;catalytic activity, acting on a nucleic acid#GO:0140640;3'-5'-RNA exonuclease activity#GO:0000175;snRNA binding#GO:0017069;exonuclease activity#GO:0004527;catalytic activity, acting on RNA#GO:0140098;RNA binding#GO:0003723;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;3'-5' exonuclease activity#GO:0008408;RNA nuclease activity#GO:0004540 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;snRNA metabolic process#GO:0016073;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;snRNA 3'-end processing#GO:0034472;snRNA processing#GO:0016180;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear body#GO:0016604;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 mRNA polyadenylation factor#PC00146 CIOIN|Ensembl=ENSCING00000023262.1|UniProtKB=H2XVF9 H2XVF9 LOC100176190 PTHR13551:SF1 BRAIN PROTEIN I3 MEMBRANE PROTEIN BRI3 CIOIN|Ensembl=ENSCING00000018267.1|UniProtKB=H2XRH0 H2XRH0 LOC104265697 PTHR28605:SF1 CTF8, CHROMOSOME TRANSMISSION FIDELITY FACTOR 8 HOMOLOG (S. CEREVISIAE) CHROMOSOME TRANSMISSION FIDELITY FACTOR 8 CIOIN|Ensembl=ENSCING00000013317.2|UniProtKB=F6XC11 F6XC11 LOC100183112 PTHR21622:SF0 COILED-COIL-HELIX-COILED-COIL-HELIX DOMAIN CONTAINING 4 COILED-COIL-HELIX-COILED-COIL-HELIX DOMAIN CONTAINING 4 protein-disulfide reductase activity#GO:0015035;disulfide oxidoreductase activity#GO:0015036;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;protein transmembrane transport#GO:0071806;nitrogen compound transport#GO:0071705;gene expression#GO:0010467;biosynthetic process#GO:0009058;protein transmembrane import into intracellular organelle#GO:0044743;establishment of protein localization#GO:0045184;organic substance transport#GO:0071702;establishment of localization#GO:0051234;protein targeting to mitochondrion#GO:0006626;nitrogen compound metabolic process#GO:0006807;protein localization to organelle#GO:0033365;protein metabolic process#GO:0019538;mitochondrial transmembrane transport#GO:1990542;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;macromolecule biosynthetic process#GO:0009059;transmembrane transport#GO:0055085;macromolecule metabolic process#GO:0043170;protein targeting#GO:0006605;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;cellular metabolic process#GO:0044237;establishment of protein localization to organelle#GO:0072594;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;protein localization to mitochondrion#GO:0070585;protein localization#GO:0008104;primary metabolic process#GO:0044238;localization#GO:0051179;mitochondrial transport#GO:0006839;cellular macromolecule localization#GO:0070727;establishment of protein localization to mitochondrion#GO:0072655;protein folding#GO:0006457;protein transport#GO:0015031 envelope#GO:0031975;membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;mitochondrial envelope#GO:0005740;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;mitochondrial intermembrane space#GO:0005758;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000007272.3|UniProtKB=F6THM1 F6THM1 PTHR16017:SF0 GASTRULATION DEFECTIVE PROTEIN 1-RELATED WD REPEAT-CONTAINING PROTEIN 70 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;site of DNA damage#GO:0090734;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;site of double-strand break#GO:0035861;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000024114.1|UniProtKB=F6PLM8 F6PLM8 PTHR24300:SF397 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 2U1 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;tetrapyrrole binding#GO:0046906;steroid hydroxylase activity#GO:0008395;oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497;heme binding#GO:0020037 response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;response to chemical#GO:0042221;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 oxygenase#PC00177;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000012047.2|UniProtKB=F7AMX9 F7AMX9 PTHR24412:SF172 KELCH PROTEIN KELCH-LIKE PROTEIN 10 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000009006.3|UniProtKB=F6PHI7 F6PHI7 PTHR12369:SF11 CHONDROITIN SYNTHASE HEXOSYLTRANSFERASE transferase activity#GO:0016740;catalytic activity#GO:0003824;glycosyltransferase activity#GO:0016757;hexosyltransferase activity#GO:0016758;UDP-glycosyltransferase activity#GO:0008194 glycosyltransferase#PC00111 CIOIN|Ensembl=ENSCING00000022363.1|UniProtKB=H2XWK9 H2XWK9 PTHR45746:SF6 LP21163P LP21163P nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 regulation of cell communication#GO:0010646;regulation of GTPase activity#GO:0043087;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;regulation of G protein-coupled receptor signaling pathway#GO:0008277;regulation of catalytic activity#GO:0050790;positive regulation of hydrolase activity#GO:0051345;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of hydrolase activity#GO:0051336 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>RGS#P00704;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>RGS#P00731 CIOIN|Ensembl=ENSCING00000021194.1|UniProtKB=H2XLM6 H2XLM6 PTHR11963:SF4 LEUCINE AMINOPEPTIDASE-RELATED AMINOPEPTIDASE NPEPL1-RELATED hydrolase activity#GO:0016787;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 metalloprotease#PC00153;protease#PC00190 CIOIN|Ensembl=ENSCING00000001112.3|UniProtKB=F7AFU8 F7AFU8 LOC445756 PTHR18939:SF4 RIBOSOME BINDING PROTEIN-1 RIBOSOME-BINDING PROTEIN 1 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000019472.1|UniProtKB=H2XKQ7 H2XKQ7 PTHR24240:SF223 OPSIN MELATONIN RECEPTOR 1B signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 signal transduction#GO:0007165;response to light stimulus#GO:0009416;cellular response to stimulus#GO:0051716;detection of stimulus#GO:0051606;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;regulation of cellular process#GO:0050794;response to radiation#GO:0009314;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;response to abiotic stimulus#GO:0009628;signaling#GO:0023052;cellular response to light stimulus#GO:0071482 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 CIOIN|Ensembl=ENSCING00000007141.3|UniProtKB=F7BH30 F7BH30 LOC100176946 PTHR11547:SF23 ARGININE OR CREATINE KINASE CREATINE KINASE B-TYPE transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301 organophosphate biosynthetic process#GO:0090407;nitrogen compound metabolic process#GO:0006807;cellular modified amino acid metabolic process#GO:0006575;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;organophosphate metabolic process#GO:0019637;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;metabolic process#GO:0008152;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 amino acid kinase#PC00045 CIOIN|Ensembl=ENSCING00000000469.3|UniProtKB=F6YW46 F6YW46 PTHR21082:SF4 PROTEIN INTURNED PROTEIN INTURNED cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cell projection organization#GO:0030030;multicellular organism development#GO:0007275;developmental process#GO:0032502;cellular component organization#GO:0016043;cellular process#GO:0009987;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;system development#GO:0048731;organelle organization#GO:0006996;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection assembly#GO:0120031 cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;cilium#GO:0005929;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000005183.3|UniProtKB=F7B7E9 F7B7E9 PTHR43326:SF1 METHIONYL-TRNA SYNTHETASE METHIONINE--TRNA LIGASE, MITOCHONDRIAL catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;ligase activity#GO:0016874;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;peptide biosynthetic process#GO:0043043;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 aminoacyl-tRNA synthetase#PC00047;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000000481.3|UniProtKB=F6QTI2 F6QTI2 PTHR45841:SF1 MRNA TURNOVER PROTEIN 4 MRTO4 MRNA TURNOVER PROTEIN 4 HOMOLOG RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;cellular component biogenesis#GO:0044085;negative regulation of biological process#GO:0048519;heterocycle catabolic process#GO:0046700;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;RNA processing#GO:0006396;gene expression#GO:0010467;biosynthetic process#GO:0009058;ribosomal large subunit biogenesis#GO:0042273;nucleobase-containing compound metabolic process#GO:0006139;cellular nitrogen compound catabolic process#GO:0044270;regulation of biological process#GO:0050789;ncRNA metabolic process#GO:0034660;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;mRNA catabolic process#GO:0006402;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;ribosome biogenesis#GO:0042254;regulation of macromolecule biosynthetic process#GO:0010556;organic substance catabolic process#GO:1901575;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;negative regulation of metabolic process#GO:0009892;nuclear-transcribed mRNA catabolic process#GO:0000956;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;aromatic compound catabolic process#GO:0019439;regulation of macromolecule metabolic process#GO:0060255;rRNA metabolic process#GO:0016072;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;ribonucleoprotein complex biogenesis#GO:0022613;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;nucleobase-containing compound catabolic process#GO:0034655;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;preribosome, large subunit precursor#GO:0030687;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;preribosome#GO:0030684 CIOIN|Ensembl=ENSCING00000014498.2|UniProtKB=F7AZ18 F7AZ18 LOC100183087 PTHR28259:SF1 FLUORIDE EXPORT PROTEIN 1-RELATED FLUORIDE EXPORT PROTEIN 1-RELATED inorganic molecular entity transmembrane transporter activity#GO:0015318;transmembrane transporter activity#GO:0022857;monoatomic anion transmembrane transporter activity#GO:0008509;inorganic anion transmembrane transporter activity#GO:0015103;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075 localization#GO:0051179;inorganic anion transmembrane transport#GO:0098661;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic anion transmembrane transport#GO:0098656;monoatomic ion transmembrane transport#GO:0034220;monoatomic anion transport#GO:0006820;transport#GO:0006810;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 CIOIN|Ensembl=ENSCING00000003327.3|UniProtKB=Q1RLH5 Q1RLH5 Ci-ZF(C2H2)-55 PTHR15921:SF3 PRE-MRNA CLEAVAGE COMPLEX II PRE-MRNA CLEAVAGE COMPLEX 2 PROTEIN PCF11 nucleic acid binding#GO:0003676;basal RNA polymerase II transcription machinery binding#GO:0001099;RNA binding#GO:0003723;RNA polymerase binding#GO:0070063;binding#GO:0005488;organic cyclic compound binding#GO:0097159;RNA polymerase core enzyme binding#GO:0043175;RNA polymerase II complex binding#GO:0000993;enzyme binding#GO:0019899;protein binding#GO:0005515;mRNA binding#GO:0003729;basal transcription machinery binding#GO:0001098 cellular aromatic compound metabolic process#GO:0006725;DNA-templated transcription#GO:0006351;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;RNA biosynthetic process#GO:0032774;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;aromatic compound biosynthetic process#GO:0019438;transcription by RNA polymerase II#GO:0006366;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;mRNA cleavage factor complex#GO:0005849;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA processing factor#PC00147;RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000011360.2|UniProtKB=F6U930 F6U930 LOC104265415 PTHR31606:SF1 WW DOMAIN BINDING PROTEIN 2, ISOFORM E WW DOMAIN BINDING PROTEIN 2, ISOFORM E molecular adaptor activity#GO:0060090;nucleic acid binding#GO:0003676;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;chromatin DNA binding#GO:0031490;binding#GO:0005488;organic cyclic compound binding#GO:0097159;chromatin binding#GO:0003682;protein-macromolecule adaptor activity#GO:0030674;DNA binding#GO:0003677;transcription coactivator activity#GO:0003713;protein-containing complex binding#GO:0044877 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of RNA biosynthetic process#GO:2001141;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of RNA metabolic process#GO:0051254;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000022986.1|UniProtKB=Q4H2T6 Q4H2T6 Ci-Smad2_3a PTHR13703:SF25 SMAD MOTHERS AGAINST DECAPENTAPLEGIC HOMOLOG cis-regulatory region sequence-specific DNA binding#GO:0000987;SMAD binding#GO:0046332;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;protein binding#GO:0005515;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nitrogen compound metabolic process#GO:0051171;response to growth factor#GO:0070848;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;cellular response to BMP stimulus#GO:0071773;cell differentiation#GO:0030154;positive regulation of biosynthetic process#GO:0009891;response to endogenous stimulus#GO:0009719;positive regulation of metabolic process#GO:0009893;anatomical structure morphogenesis#GO:0009653;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;response to BMP#GO:0071772;regulation of macromolecule biosynthetic process#GO:0010556;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;signaling#GO:0023052;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;cellular response to endogenous stimulus#GO:0071495;regulation of DNA-templated transcription#GO:0006355;BMP signaling pathway#GO:0030509;cell communication#GO:0007154;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;activin receptor signaling pathway#GO:0032924;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular response to growth factor stimulus#GO:0071363;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;anatomical structure development#GO:0048856;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007;positive regulation of RNA metabolic process#GO:0051254;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218 MYO signaling pathway#P06215>SMOX#P06314;Activin beta signaling pathway#P06210>SMOX#P06236;ALP23B signaling pathway#P06209>SMOX#P06224;BMP/activin signaling pathway-drosophila#P06211>R-Smad#P06245;TGF-beta signaling pathway#P00052>RSmads#P01292 CIOIN|Ensembl=ENSCING00000016695.2|UniProtKB=F6RU13 F6RU13 LOC104265377 PTHR18860:SF159 14-3-3 PROTEIN 14-3-3 PROTEIN ZETA localization#GO:0051179;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular localization#GO:0051641;cellular response to stimulus#GO:0051716;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052;protein localization#GO:0008104 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 Parkinson disease#P00049>14-3-3#P01238;FGF signaling pathway#P00021>14-3-3#P00624;EGF receptor signaling pathway#P00018>14-3-3#P00539;PI3 kinase pathway#P00048>14-3-3#P01206 CIOIN|Ensembl=ENSCING00000008948.3|UniProtKB=F6Q662 F6Q662 PTHR11937:SF387 ACTIN ACTIN-LIKE PROTEIN 53D intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 actin and actin related protein#PC00039;cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 Wnt signaling pathway#P00057>NFAT Target Genes#G01559;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>F-actin#P00858;Alzheimer disease-presenilin pathway#P00004>actin#P00114;Integrin signalling pathway#P00034>Actin#P00944;Huntington disease#P00029>Actin#P00807;Nicotinic acetylcholine receptor signaling pathway#P00044>Actin#P01090;Cadherin signaling pathway#P00012>F-actin#P00470;Cytoskeletal regulation by Rho GTPase#P00016>Actin#P00512 CIOIN|Ensembl=ENSCING00000021045.1|UniProtKB=H2XL19 H2XL19 LOC100178221 PTHR19325:SF560 COMPLEMENT COMPONENT-RELATED SUSHI DOMAIN-CONTAINING SUSHI, VON WILLEBRAND FACTOR TYPE A, EGF AND PENTRAXIN DOMAIN-CONTAINING PROTEIN 1 complement component#PC00078 CIOIN|Ensembl=ENSCING00000023791.1|UniProtKB=H2XWY7 H2XWY7 LOC100176037 PTHR45615:SF27 MYOSIN HEAVY CHAIN, NON-MUSCLE MYOSIN HEAVY CHAIN, MUSCLE microfilament motor activity#GO:0000146;cytoskeletal protein binding#GO:0008092;ATP-dependent activity#GO:0140657;binding#GO:0005488;actin filament binding#GO:0051015;cytoskeletal motor activity#GO:0003774;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779 supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;supramolecular fiber#GO:0099512;supramolecular polymer#GO:0099081;myosin complex#GO:0016459;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 CIOIN|Ensembl=ENSCING00000012429.2|UniProtKB=L7N0U3 L7N0U3 PTHR12480:SF41 ARGININE DEMETHYLASE AND LYSYL-HYDROXYLASE JMJD JMJC DOMAIN-CONTAINING PROTEIN sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;dioxygenase activity#GO:0051213;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity#GO:0016491 positive regulation of gene expression#GO:0010628;positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of protein metabolic process#GO:0051246;regulation of amide metabolic process#GO:0034248;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;protein modification process#GO:0036211;regulation of cellular component organization#GO:0051128;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;protein hydroxylation#GO:0018126;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;positive regulation of biological process#GO:0048518;positive regulation of translation#GO:0045727;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;regulation of protein-containing complex disassembly#GO:0043244;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;positive regulation of protein metabolic process#GO:0051247;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;post-transcriptional regulation of gene expression#GO:0010608;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;regulation of translation#GO:0006417;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000018066.1|UniProtKB=H2Y395 H2Y395 LOC100178418 PTHR23074:SF86 AAA DOMAIN-CONTAINING SPASTIN pyrophosphatase activity#GO:0016462;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;ATP hydrolysis activity#GO:0016887 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 CIOIN|Ensembl=ENSCING00000004582.3|UniProtKB=F6WQS5 F6WQS5 LOC100180661 PTHR22166:SF12 ENDOPLASMIC RETICULUM JUNCTION FORMATION PROTEIN LUNAPARK ENDOPLASMIC RETICULUM JUNCTION FORMATION PROTEIN LUNAPARK endomembrane system organization#GO:0010256;cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;endoplasmic reticulum organization#GO:0007029;cellular process#GO:0009987;endoplasmic reticulum tubular network organization#GO:0071786;organelle organization#GO:0006996 cytoplasm#GO:0005737;endoplasmic reticulum tubular network#GO:0071782;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000001227.3|UniProtKB=H2XX04 H2XX04 PTHR43602:SF1 FAMILY NOT NAMED ENOYL-COA HYDRATASE DOMAIN-CONTAINING PROTEIN 3, MITOCHONDRIAL carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829;catalytic activity#GO:0003824;hydro-lyase activity#GO:0016836 CIOIN|Ensembl=ENSCING00000007268.3|UniProtKB=F6THL0 F6THL0 LOC100176589 PTHR11630:SF66 DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER DNA REPLICATION LICENSING FACTOR MCM4 DNA metabolism protein#PC00009 CIOIN|Ensembl=ENSCING00000006692.3|UniProtKB=F7ASB0 F7ASB0 LOC100184101 PTHR31809:SF0 BUD13 HOMOLOG BUD13 HOMOLOG nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;U2-type spliceosomal complex#GO:0005684;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000008104.3|UniProtKB=H2XN32 H2XN32 PTHR22146:SF8 CAT EYE SYNDROME CRITICAL REGION PROTEIN 6 PROTEIN FAM166B CIOIN|Ensembl=ENSCING00000007058.3|UniProtKB=F6WVU8 F6WVU8 PTHR24221:SF165 ATP-BINDING CASSETTE SUB-FAMILY B BILE SALT EXPORT PUMP transmembrane transporter activity#GO:0022857;primary active transmembrane transporter activity#GO:0015399;ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 localization#GO:0051179;cellular process#GO:0009987;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810 plasma membrane region#GO:0098590;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;apical part of cell#GO:0045177;plasma membrane#GO:0005886;apical plasma membrane#GO:0016324 ATP-binding cassette (ABC) transporter#PC00003;transporter#PC00227 CIOIN|Ensembl=ENSCING00000001163.3|UniProtKB=A0A1W3JHQ5 A0A1W3JHQ5 LOC100176476 PTHR14856:SF9 PQ-LOOP REPEAT-CONTAINING PROTEIN 1-LIKE PROTEIN PQ-LOOP REPEAT-CONTAINING PROTEIN 1 endosomal transport#GO:0016197;cellular localization#GO:0051641;organophosphate ester transport#GO:0015748;macromolecule localization#GO:0033036;membrane organization#GO:0061024;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;regulation of membrane lipid distribution#GO:0097035;phospholipid transport#GO:0015914;cellular process#GO:0009987;lipid transport#GO:0006869;cytosolic transport#GO:0016482;retrograde transport, endosome to Golgi#GO:0042147;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;biological regulation#GO:0065007;lipid translocation#GO:0034204;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;lipid localization#GO:0010876;phospholipid translocation#GO:0045332 trans-Golgi network#GO:0005802;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;organelle subcompartment#GO:0031984;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;Golgi apparatus subcompartment#GO:0098791 CIOIN|Ensembl=ENSCING00000024196.1|UniProtKB=H2XYU8 H2XYU8 PTHR12599:SF0 PTERIN-4-ALPHA-CARBINOLAMINE DEHYDRATASE PTERIN-4-ALPHA-CARBINOLAMINE DEHYDRATASE carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829;catalytic activity#GO:0003824;hydro-lyase activity#GO:0016836 dehydratase#PC00091;lyase#PC00144 CIOIN|Ensembl=ENSCING00000014284.2|UniProtKB=F6VE17 F6VE17 LOC100185254 PTHR13476:SF0 CHROMATIN MODIFICATION-RELATED PROTEIN MEAF6 CHROMATIN MODIFICATION-RELATED PROTEIN MEAF6 histone acetyltransferase complex#GO:0000123;acetyltransferase complex#GO:1902493;protein-DNA complex#GO:0032993;chromatin#GO:0000785;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein acetyltransferase complex#GO:0031248;protein-containing complex#GO:0032991;chromosome#GO:0005694 CIOIN|Ensembl=ENSCING00000002722.3|UniProtKB=F6UCV3 F6UCV3 PTHR10157:SF23 DOPAMINE BETA HYDROXYLASE RELATED MOXD1 HOMOLOG 1 hydroxylase#PC00122 CIOIN|Ensembl=ENSCING00000009494.3|UniProtKB=F6Y9F6 F6Y9F6 PTHR23032:SF13 BRO1 DOMAIN-CONTAINING PROTEIN BROX BRO1 DOMAIN-CONTAINING PROTEIN BROX CIOIN|Ensembl=ENSCING00000008329.3|UniProtKB=F7B4F4 F7B4F4 LOC100181260 PTHR15367:SF2 DNA-DIRECTED RNA POLYMERASE III DNA-DIRECTED RNA POLYMERASE III SUBUNIT nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;DNA-directed RNA polymerase complex#GO:0000428;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695;RNA polymerase complex#GO:0030880;protein-containing complex#GO:0032991;nuclear DNA-directed RNA polymerase complex#GO:0055029;RNA polymerase III complex#GO:0005666;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 RNA metabolism protein#PC00031;DNA-directed RNA polymerase#PC00019 CIOIN|Ensembl=ENSCING00000003484.3|UniProtKB=F6UA31 F6UA31 PTHR45617:SF173 LEUCINE RICH REPEAT FAMILY PROTEIN RE54577P scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000002110.3|UniProtKB=F6ZR87 F6ZR87 PTHR31740:SF2 CENTROMERE PROTEIN L CENTROMERE PROTEIN L CIOIN|Ensembl=ENSCING00000022752.1|UniProtKB=H2XYZ9 H2XYZ9 PTHR12021:SF26 THYMOSIN BETA THYMOSIN BETA cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;actin binding#GO:0003779;binding#GO:0005488;actin monomer binding#GO:0003785 negative regulation of protein polymerization#GO:0032272;cellular localization#GO:0051641;negative regulation of biological process#GO:0048519;macromolecule localization#GO:0033036;regulation of locomotion#GO:0040012;regulation of cellular component organization#GO:0051128;regulation of actin polymerization or depolymerization#GO:0008064;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;regulation of protein-containing complex assembly#GO:0043254;regulation of cell migration#GO:0030334;regulation of biological quality#GO:0065008;regulation of cellular component biogenesis#GO:0044087;negative regulation of organelle organization#GO:0010639;regulation of actin cytoskeleton organization#GO:0032956;regulation of actin filament-based process#GO:0032970;negative regulation of cellular component organization#GO:0051129;regulation of protein polymerization#GO:0032271;negative regulation of cellular process#GO:0048523;regulation of anatomical structure size#GO:0090066;regulation of cell motility#GO:2000145;regulation of actin filament length#GO:0030832;regulation of organelle organization#GO:0033043;regulation of actin filament organization#GO:0110053;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of actin filament polymerization#GO:0030833;regulation of cellular component size#GO:0032535;protein localization#GO:0008104;negative regulation of supramolecular fiber organization#GO:1902904;regulation of supramolecular fiber organization#GO:1902903;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;maintenance of location#GO:0051235;regulation of cellular process#GO:0050794;negative regulation of actin filament polymerization#GO:0030837;maintenance of location in cell#GO:0051651;biological regulation#GO:0065007;negative regulation of protein-containing complex assembly#GO:0031333;negative regulation of cytoskeleton organization#GO:0051494 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 CIOIN|Ensembl=ENSCING00000001503.3|UniProtKB=F6S8N9 F6S8N9 PTHR42693:SF47 ARYLSULFATASE FAMILY MEMBER N-ACETYLGALACTOSAMINE-6-SULFATASE hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000008158.3|UniProtKB=H2XYW2 H2XYW2 LOC100181442 PTHR11782:SF127 ADENOSINE/GUANOSINE DIPHOSPHATASE NTPASE, ISOFORM F metabolite interconversion enzyme#PC00262;nucleotide phosphatase#PC00173;phosphatase#PC00181 CIOIN|Ensembl=ENSCING00000004296.3|UniProtKB=F6TSV2 F6TSV2 PTHR10663:SF388 GUANYL-NUCLEOTIDE EXCHANGE FACTOR GOLGI-SPECIFIC BREFELDIN A-RESISTANCE GUANINE NUCLEOTIDE EXCHANGE FACTOR 1 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 CIOIN|Ensembl=ENSCING00000003293.3|UniProtKB=F6W254 F6W254 PTHR10579:SF172 CALCIUM-ACTIVATED CHLORIDE CHANNEL REGULATOR CALCIUM-ACTIVATED CHLORIDE CHANNEL REGULATOR 4 PRECURSOR-RELATED ion channel#PC00133;transporter#PC00227 CIOIN|Ensembl=ENSCING00000022218.1|UniProtKB=A0A1W5BI84 A0A1W5BI84 LOC100183282 PTHR33724:SF1 INTRAFLAGELLAR TRANSPORT PROTEIN 43 HOMOLOG INTRAFLAGELLAR TRANSPORT PROTEIN 43 HOMOLOG cilium organization#GO:0044782;cellular localization#GO:0051641;cell projection organization#GO:0030030;transport#GO:0006810;microtubule-based movement#GO:0007018;cellular component organization#GO:0016043;cellular process#GO:0009987;intraciliary retrograde transport#GO:0035721;transport along microtubule#GO:0010970;plasma membrane bounded cell projection organization#GO:0120036;intraciliary transport#GO:0042073;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;microtubule-based transport#GO:0099111;microtubule-based process#GO:0007017;establishment of localization#GO:0051234;organelle organization#GO:0006996;cytoskeleton-dependent intracellular transport#GO:0030705;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;protein-containing complex localization#GO:0031503 protein-containing complex#GO:0032991;intraciliary transport particle A#GO:0030991;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;cilium#GO:0005929;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intraciliary transport particle#GO:0030990 CIOIN|Ensembl=ENSCING00000013587.2|UniProtKB=F6XN50 F6XN50 PTHR23252:SF24 INTIMAL THICKNESS RECEPTOR-RELATED TRANSMEMBRANE PROTEIN 145 CIOIN|Ensembl=ENSCING00000006469.3|UniProtKB=F6Q558 F6Q558 LOC100185452 PTHR12800:SF4 CDC37-RELATED HSP90 CO-CHAPERONE CDC37 protein binding#GO:0005515;heat shock protein binding#GO:0031072;protein-folding chaperone binding#GO:0051087;unfolded protein binding#GO:0051082;binding#GO:0005488 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;regulation of protein stability#GO:0031647;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;protein stabilization#GO:0050821;primary metabolic process#GO:0044238;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;protein folding#GO:0006457;biological regulation#GO:0065007;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 chaperone#PC00072 CIOIN|Ensembl=ENSCING00000004414.3|UniProtKB=F6YNR2 F6YNR2 LOC100186295 PTHR43248:SF3 2-SUCCINYL-6-HYDROXY-2,4-CYCLOHEXADIENE-1-CARBOXYLATE SYNTHASE AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN metabolite interconversion enzyme#PC00262;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000012216.2|UniProtKB=F7BP51 F7BP51 PTHR15296:SF1 MEMBRANE-ASSOCIATED PROTEIN MAP17 PDZK1 INTERACTING PROTEIN 1 CIOIN|Ensembl=ENSCING00000008288.3|UniProtKB=F6QGV6 F6QGV6 PTHR46531:SF1 ZINC TRANSPORTER 6 ZINC TRANSPORTER 6 localization#GO:0051179;monoatomic cation transport#GO:0006812;transition metal ion transport#GO:0000041;metal ion transport#GO:0030001;monoatomic ion transport#GO:0006811;establishment of localization#GO:0051234;transport#GO:0006810 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transporter#PC00227 CIOIN|Ensembl=ENSCING00000006424.4|UniProtKB=F6QRJ2 F6QRJ2 LOC100185739 PTHR45671:SF10 SOLUTE CARRIER FAMILY 25 (MITOCHONDRIAL CARRIER PHOSPHATE CARRIER), MEMBER 3, LIKE-RELATED-RELATED SOLUTE CARRIER FAMILY 25 MEMBER 3 secondary active transmembrane transporter activity#GO:0015291;inorganic molecular entity transmembrane transporter activity#GO:0015318;transmembrane transporter activity#GO:0022857;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215 localization#GO:0051179;inorganic anion transmembrane transport#GO:0098661;phosphate ion transport#GO:0006817;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;inorganic anion transport#GO:0015698 envelope#GO:0031975;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;organelle membrane#GO:0031090;organelle inner membrane#GO:0019866;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227 mitochondrial carrier protein#PC00158;secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000015961.2|UniProtKB=F6X413 F6X413 LOC100175281 PTHR13280:SF17 PHOSPHOFURIN ACIDIC CLUSTER SORTING PROTEIN KRUEPPEL TARGET AT 95D, ISOFORM A CIOIN|Ensembl=ENSCING00000012687.2|UniProtKB=F6U3G5 F6U3G5 PTHR10429:SF0 DNA-3-METHYLADENINE GLYCOSYLASE DNA-3-METHYLADENINE GLYCOSYLASE catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;catalytic activity, acting on DNA#GO:0140097;DNA N-glycosylase activity#GO:0019104;catalytic activity#GO:0003824 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;base-excision repair#GO:0006284;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;DNA damage response#GO:0006974;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 DNA metabolism protein#PC00009;DNA glycosylase#PC00010 CIOIN|Ensembl=ENSCING00000018343.1|UniProtKB=F6QFH5 F6QFH5 LOC100184016 PTHR11822:SF21 NADP-SPECIFIC ISOCITRATE DEHYDROGENASE ISOCITRATE DEHYDROGENASE [NADP], MITOCHONDRIAL dehydrogenase#PC00092;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000002209.3|UniProtKB=F6ZPY9 F6ZPY9 PTHR10340:SF57 SPHINGOMYELIN PHOSPHODIESTERASE METALLOPHOS DOMAIN-CONTAINING PROTEIN phosphodiesterase#PC00185;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000010237.3|UniProtKB=F6QFG5 F6QFG5 PTHR21024:SF0 GROWTH HORMONE-INDUCIBLE SOLUBLE PROTEIN-RELATED ELECTRON TRANSFER FLAVOPROTEIN REGULATORY FACTOR 1 cellular respiration#GO:0045333;respiratory electron transport chain#GO:0022904;generation of precursor metabolites and energy#GO:0006091;cellular metabolic process#GO:0044237;electron transport chain#GO:0022900;cellular process#GO:0009987;energy derivation by oxidation of organic compounds#GO:0015980;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000011462.2|UniProtKB=F6ZUD7 F6ZUD7 PTHR22950:SF349 AMINO ACID TRANSPORTER AMINO ACID TRANSPORTER TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN L-amino acid transmembrane transporter activity#GO:0015179;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;amino acid transmembrane transporter activity#GO:0015171;organic anion transmembrane transporter activity#GO:0008514;organic acid transmembrane transporter activity#GO:0005342;transporter activity#GO:0005215 localization#GO:0051179;organic substance transport#GO:0071702;amino acid transmembrane transport#GO:0003333;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;organic anion transport#GO:0015711;amino acid transport#GO:0006865;organic acid transport#GO:0015849;transport#GO:0006810;nitrogen compound transport#GO:0071705;organic acid transmembrane transport#GO:1903825;carboxylic acid transport#GO:0046942;cellular process#GO:0009987;carboxylic acid transmembrane transport#GO:1905039 bounding membrane of organelle#GO:0098588;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;vacuolar membrane#GO:0005774;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 amino acid transporter#PC00046;transporter#PC00227 CIOIN|Ensembl=ENSCING00000016335.2|UniProtKB=F6VHE0 F6VHE0 PTHR18950:SF0 PROGESTERONE-INDUCED BLOCKING FACTOR 1 PROGESTERONE IMMUNOMODULATORY BINDING FACTOR 1 organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cell projection organization#GO:0030030;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000016143.2|UniProtKB=F6SUH2 F6SUH2 PTHR31158:SF1 DUAL OXIDASE 2 DOXA1 FACTOR-RELATED cellular anatomical entity#GO:0110165;membrane#GO:0016020 oxidase#PC00175;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000006489.3|UniProtKB=F6Q1R5 F6Q1R5 LOC100184793 PTHR11929:SF145 ALPHA- 1,3 -FUCOSYLTRANSFERASE ALPHA-(1,3)-FUCOSYLTRANSFERASE FUT-1 transferase activity#GO:0016740;fucosyltransferase activity#GO:0008417;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 glycosylation#GO:0070085;metabolic process#GO:0008152 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000021567.1|UniProtKB=H2XM43 H2XM43 PTHR13357:SF1 SH3 ADAPTER PROTEIN SPIN90 NCK INTERACTING PROTEIN WITH SH3 DOMAIN NCK-INTERACTING PROTEIN WITH SH3 DOMAIN protein-containing complex binding#GO:0044877;binding#GO:0005488 localization#GO:0051179;vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234;cellular process#GO:0009987;import into cell#GO:0098657;endocytosis#GO:0006897;transport#GO:0006810 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000007101.3|UniProtKB=F6VLU0 F6VLU0 PTHR24033:SF224 EGF-LIKE DOMAIN-CONTAINING PROTEIN C-TYPE LECTIN CIOIN|Ensembl=ENSCING00000009351.3|UniProtKB=F6XL13 F6XL13 LOC100185647 PTHR11474:SF126 TYROSINASE FAMILY MEMBER TYROSINASE-LIKE PROTEIN TYR-1-RELATED oxygenase#PC00177;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000012292.2|UniProtKB=F7BEK1 F7BEK1 PTHR21206:SF0 SLD5 PROTEIN DNA REPLICATION COMPLEX GINS PROTEIN SLD5 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;double-strand break repair via homologous recombination#GO:0000724;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;response to stress#GO:0006950;double-strand break repair via break-induced replication#GO:0000727;nitrogen compound metabolic process#GO:0006807;recombinational repair#GO:0000725;cellular response to stress#GO:0033554;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-DNA complex#GO:0032993;DNA replication preinitiation complex#GO:0031261;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular anatomical structure#GO:0005622;GINS complex#GO:0000811;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 CIOIN|Ensembl=ENSCING00000009551.3|UniProtKB=F6U8H5 F6U8H5 PTHR15722:SF7 IFT140/172-RELATED INTRAFLAGELLAR TRANSPORT PROTEIN 140 HOMOLOG cilium organization#GO:0044782;cellular localization#GO:0051641;cell projection organization#GO:0030030;transport#GO:0006810;microtubule-based movement#GO:0007018;cellular component organization#GO:0016043;intraciliary retrograde transport#GO:0035721;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;transport along microtubule#GO:0010970;intraciliary transport#GO:0042073;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;microtubule-based transport#GO:0099111;establishment of localization#GO:0051234;microtubule-based process#GO:0007017;organelle organization#GO:0006996;cytoskeleton-dependent intracellular transport#GO:0030705;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;protein-containing complex localization#GO:0031503 axoneme#GO:0005930;microtubule organizing center#GO:0005815;intraciliary transport particle A#GO:0030991;cytoplasmic region#GO:0099568;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;ciliary basal body#GO:0036064;ciliary plasm#GO:0097014;plasma membrane bounded cell projection cytoplasm#GO:0032838;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cytoskeleton#GO:0005856;cilium#GO:0005929;intraciliary transport particle#GO:0030990 structural protein#PC00211 CIOIN|Ensembl=ENSCING00000008909.3|UniProtKB=F6QBB9 F6QBB9 PTHR11949:SF53 INTERFERON REGULATORY FACTOR IRF TRYPTOPHAN PENTAD REPEAT DOMAIN-CONTAINING PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 CIOIN|Ensembl=ENSCING00000004280.3|UniProtKB=F6UGN5 F6UGN5 PTHR12262:SF0 CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 9 CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 9 negative regulation of gene expression#GO:0010629;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;negative regulation of biosynthetic process#GO:0009890;regulation of amide metabolic process#GO:0034248;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of translation#GO:0017148;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;post-transcriptional regulation of gene expression#GO:0010608;biological regulation#GO:0065007;regulation of translation#GO:0006417;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;protein-containing complex#GO:0032991;P-body#GO:0000932;CCR4-NOT complex#GO:0030014;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic ribonucleoprotein granule#GO:0036464 CIOIN|Ensembl=ENSCING00000024787.1|UniProtKB=H2XX99 H2XX99 PTHR22545:SF0 CENTROSOMAL PROTEIN OF 95 KDA CENTROSOMAL PROTEIN OF 95 KDA intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;spindle pole#GO:0000922;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;spindle#GO:0005819;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000001784.3|UniProtKB=F6X600 F6X600 LOC100182622 PTHR21091:SF169 METHYLTETRAHYDROFOLATE:HOMOCYSTEINE METHYLTRANSFERASE RELATED UROPORPHYRINOGEN DECARBOXYLASE methyltransferase#PC00155 Heme biosynthesis#P02746>Uroporphyrinogen decarboxylase#P02975 CIOIN|Ensembl=ENSCING00000006101.3|UniProtKB=F6YWU5 F6YWU5 PTHR13826:SF14 INTESTINAL TREFOIL FACTOR-RELATED TREFOIL FACTOR 2 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 CIOIN|Ensembl=ENSCING00000001184.3|UniProtKB=F6WAH3 F6WAH3 LOC100186065 PTHR19134:SF527 RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 7 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;protein tyrosine phosphatase activity#GO:0004725;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 protein phosphatase#PC00195;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000020684.1|UniProtKB=H2XNZ6 H2XNZ6 PTHR48041:SF139 ABC TRANSPORTER G FAMILY MEMBER 28 PROTEIN SCARLET transmembrane transporter activity#GO:0022857;primary active transmembrane transporter activity#GO:0015399;ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 localization#GO:0051179;establishment of localization#GO:0051234;cellular process#GO:0009987;transmembrane transport#GO:0055085;transport#GO:0006810 cellular anatomical entity#GO:0110165;membrane#GO:0016020 ATP-binding cassette (ABC) transporter#PC00003;transporter#PC00227 CIOIN|Ensembl=ENSCING00000020885.1|UniProtKB=F6TJJ0 F6TJJ0 PTHR10590:SF4 SODIUM/NUCLEOSIDE COTRANSPORTER SOLUTE CARRIER FAMILY 28 MEMBER 3 carbohydrate derivative transmembrane transporter activity#GO:1901505;secondary active transmembrane transporter activity#GO:0015291;nucleoside transmembrane transporter activity#GO:0005337;transmembrane transporter activity#GO:0022857;symporter activity#GO:0015293;nucleobase-containing compound transmembrane transporter activity#GO:0015932;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215 localization#GO:0051179;organic substance transport#GO:0071702;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;nucleobase-containing compound transport#GO:0015931;transport#GO:0006810;nitrogen compound transport#GO:0071705;cellular process#GO:0009987;carbohydrate derivative transport#GO:1901264 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transporter#PC00227 CIOIN|Ensembl=ENSCING00000003898.3|UniProtKB=F7AS27 F7AS27 PTHR15708:SF4 ACTIN BUNDLING/MISSING IN METASTASIS-RELATED FI21477P1-RELATED cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;lipid binding#GO:0008289;phospholipid binding#GO:0005543;actin binding#GO:0003779;binding#GO:0005488 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cell projection organization#GO:0030030;membrane organization#GO:0061024;cellular component organization#GO:0016043;cellular process#GO:0009987;cell projection assembly#GO:0030031 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;side of membrane#GO:0098552;cytoplasmic side of plasma membrane#GO:0009898;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 CIOIN|Ensembl=ENSCING00000023278.1|UniProtKB=H2XRF2 H2XRF2 LOC100184789 PTHR12232:SF0 SH3 DOMAIN-BINDING GLUTAMIC ACID-RICH-LIKE PROTEIN THIOREDOXIN DOMAIN-CONTAINING PROTEIN cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000004360.3|UniProtKB=F6S6A5 F6S6A5 LOC100185699 PTHR12588:SF0 MYOINOSITOL OXYGENASE INOSITOL OXYGENASE oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497 organic hydroxy compound metabolic process#GO:1901615;small molecule catabolic process#GO:0044282;catabolic process#GO:0009056;alcohol metabolic process#GO:0006066;organic substance catabolic process#GO:1901575;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704 oxygenase#PC00177;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000000615.3|UniProtKB=F6RS06 F6RS06 LOC100182215 PTHR21028:SF2 SI:CH211-156B7.4 CYTH DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000007174.3|UniProtKB=F6ZAX9 F6ZAX9 PTHR10404:SF81 N-ACETYLATED-ALPHA-LINKED ACIDIC DIPEPTIDASE N-ACETYLATED ALPHA-LINKED ACIDIC DIPEPTIDASE 2 hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;carboxypeptidase activity#GO:0004180 metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000023589.1|UniProtKB=H2Y1J8 H2Y1J8 PTHR34490:SF1 PROTEIN CBG12054-RELATED GALAXIN-LIKE CIOIN|Ensembl=ENSCING00000002599.3|UniProtKB=F6TQT4 F6TQT4 LOC100182760 PTHR12544:SF29 GLUTAMINASE GLUTAMINASE hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824 dicarboxylic acid metabolic process#GO:0043648;proteinogenic amino acid biosynthetic process#GO:0170038;organonitrogen compound catabolic process#GO:1901565;biosynthetic process#GO:0009058;carboxylic acid biosynthetic process#GO:0046394;amino acid catabolic process#GO:0009063;nitrogen compound metabolic process#GO:0006807;glutamate metabolic process#GO:0006536;amino acid biosynthetic process#GO:0008652;alpha-amino acid metabolic process#GO:1901605;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;L-amino acid metabolic process#GO:0170033;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248;organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;proteinogenic amino acid metabolic process#GO:0170039;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;alpha-amino acid biosynthetic process#GO:1901607;L-amino acid biosynthetic process#GO:0170034;small molecule biosynthetic process#GO:0044283;carboxylic acid metabolic process#GO:0019752;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000012680.2|UniProtKB=F6U3K8 F6U3K8 LOC100181040 PTHR43015:SF1 D-RIBITOL-5-PHOSPHATE CYTIDYLYLTRANSFERASE D-RIBITOL-5-PHOSPHATE CYTIDYLYLTRANSFERASE transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000000018.3|UniProtKB=F6WHJ7 F6WHJ7 PTHR22168:SF3 TMEM26 PROTEIN TRANSMEMBRANE PROTEIN 26 CIOIN|Ensembl=ENSCING00000013288.2|UniProtKB=F6UK15 F6UK15 PTHR13844:SF7 SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY D BRAHMA-ASSOCIATED PROTEIN OF 60 KDA regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;catalytic complex#GO:1902494;ATPase complex#GO:1904949;SWI/SNF superfamily-type complex#GO:0070603;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;SWI/SNF complex#GO:0016514;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 chromatin/chromatin-binding, or -regulatory protein#PC00077 Wnt signaling pathway#P00057>SWI/SNF#P01435 CIOIN|Ensembl=ENSCING00000021075.1|UniProtKB=H2Y3L9 H2Y3L9 LOC100182620 PTHR23105:SF38 RIBOSOMAL PROTEIN L7AE FAMILY MEMBER NHP2-LIKE PROTEIN 1 ribosomal protein#PC00202 CIOIN|Ensembl=ENSCING00000023837.1|UniProtKB=H2Y2A0 H2Y2A0 PTHR23249:SF15 TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 4 localization#GO:0051179;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;establishment of localization#GO:0051234;transport#GO:0006810;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987 protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535;vesicle tethering complex#GO:0099023;TRAPP complex#GO:0030008 membrane traffic protein#PC00150 CIOIN|Ensembl=ENSCING00000008738.3|UniProtKB=F6TMF8 F6TMF8 PTHR46105:SF28 AGAP004733-PA ZINC FINGER PROTEIN 37-LIKE sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 CIOIN|Ensembl=ENSCING00000021400.1|UniProtKB=Q1RL59 Q1RL59 Ci-ZF(ZZ)-4 PTHR12268:SF14 E3 UBIQUITIN-PROTEIN LIGASE KCMF1 DYSTROPHIN-1 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000005127.3|UniProtKB=F6VYB4 F6VYB4 LOC100176263 PTHR16650:SF6 C21ORF13-RELATED GH21622P cilium organization#GO:0044782;cellular localization#GO:0051641;cell projection organization#GO:0030030;transport#GO:0006810;microtubule-based movement#GO:0007018;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;transport along microtubule#GO:0010970;intraciliary transport#GO:0042073;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;microtubule-based transport#GO:0099111;establishment of localization#GO:0051234;microtubule-based process#GO:0007017;organelle organization#GO:0006996;cytoskeleton-dependent intracellular transport#GO:0030705;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;protein-containing complex localization#GO:0031503 axoneme#GO:0005930;cytoplasmic region#GO:0099568;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;plasma membrane bounded cell projection cytoplasm#GO:0032838;membrane-bounded organelle#GO:0043227;ciliary plasm#GO:0097014;cytoskeleton#GO:0005856;cell projection#GO:0042995;cilium#GO:0005929 CIOIN|Ensembl=ENSCING00000022254.1|UniProtKB=H2XTC9 H2XTC9 LOC100178367 PTHR10562:SF56 SMALL UBIQUITIN-RELATED MODIFIER SMALL UBIQUITIN-RELATED MODIFIER enzyme binding#GO:0019899;protein binding#GO:0005515;binding#GO:0005488;ubiquitin-like protein ligase binding#GO:0044389 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;protein sumoylation#GO:0016925;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000018771.1|UniProtKB=H2XPG6 H2XPG6 LOC100175761 PTHR45622:SF76 UBIQUITIN-PROTEIN LIGASE E3A-RELATED HECT AND RLD DOMAIN CONTAINING E3 UBIQUITIN LIGASE 4, ISOFORM C transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000006653.3|UniProtKB=A0A140TAT7 A0A140TAT7 LOC100176513 PTHR11680:SF28 SERINE HYDROXYMETHYLTRANSFERASE SERINE HYDROXYMETHYLTRANSFERASE, MITOCHONDRIAL transferase activity#GO:0016740;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;heterocyclic compound binding#GO:1901363;transferase activity, transferring one-carbon groups#GO:0016741;anion binding#GO:0043168;ion binding#GO:0043167 cellular aromatic compound metabolic process#GO:0006725;organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;proteinogenic amino acid metabolic process#GO:0170039;heterocycle metabolic process#GO:0046483;proteinogenic amino acid biosynthetic process#GO:0170038;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;folic acid-containing compound metabolic process#GO:0006760;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;organic cyclic compound metabolic process#GO:1901360;alpha-amino acid biosynthetic process#GO:1901607;nitrogen compound metabolic process#GO:0006807;cellular modified amino acid metabolic process#GO:0006575;amino acid biosynthetic process#GO:0008652;alpha-amino acid metabolic process#GO:1901605;small molecule biosynthetic process#GO:0044283;L-amino acid biosynthetic process#GO:0170034;carboxylic acid metabolic process#GO:0019752;L-amino acid metabolic process#GO:0170033;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 methyltransferase#PC00155;metabolite interconversion enzyme#PC00262 Serine glycine biosynthesis#P02776>Glycine hydroxymethyltransferase#P03158 CIOIN|Ensembl=ENSCING00000017598.2|UniProtKB=F6ZF81 F6ZF81 PTHR14002:SF20 ENDOGLIN/TGF-BETA RECEPTOR TYPE III ZONA PELLUCIDA-LIKE DOMAIN-CONTAINING PROTEIN 1 transmembrane signal receptor#PC00197 CIOIN|Ensembl=ENSCING00000005410.3|UniProtKB=F6Z9J5 F6Z9J5 PTHR13083:SF3 WD REPEAT-CONTAINING PROTEIN 91 WD REPEAT-CONTAINING PROTEIN 91 enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207 localization#GO:0051179;endosomal transport#GO:0016197;cellular localization#GO:0051641;establishment of localization#GO:0051234;transport#GO:0006810;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;cellular process#GO:0009987;early endosome to late endosome transport#GO:0045022 bounding membrane of organelle#GO:0098588;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;early endosome#GO:0005769;late endosome membrane#GO:0031902;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endosome membrane#GO:0010008;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;early endosome membrane#GO:0031901;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle membrane#GO:0030659;late endosome#GO:0005770 CIOIN|Ensembl=ENSCING00000004066.3|UniProtKB=A0A1W5B5J3 A0A1W5B5J3 LOC100187185 PTHR24291:SF201 CYTOCHROME P450 FAMILY 4 CYTOCHROME P450, FAMILY 4, SUBFAMILY B, POLYPEPTIDE 7 oxygenase#PC00177;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000018496.1|UniProtKB=H2XKD8 H2XKD8 PTHR12884:SF0 60S RIBOSOMAL PROTEIN L29 60S RIBOSOMAL PROTEIN L29 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cytoplasmic translation#GO:0002181;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic large ribosomal subunit#GO:0022625;large ribosomal subunit#GO:0015934;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000013017.2|UniProtKB=A0A1W2WP07 A0A1W2WP07 LOC100179092 PTHR10934:SF2 60S RIBOSOMAL PROTEIN L18 LARGE RIBOSOMAL SUBUNIT PROTEIN EL18 structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;structural molecule activity#GO:0005198;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic large ribosomal subunit#GO:0022625;large ribosomal subunit#GO:0015934;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;ribosomal subunit#GO:0044391 ribosomal protein#PC00202;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000001926.3|UniProtKB=F6ZJ39 F6ZJ39 PTHR13815:SF7 GOLGIN-84 GOLGIN SUBFAMILY A MEMBER 5 localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;Golgi organization#GO:0007030;establishment of localization#GO:0051234;intra-Golgi vesicle-mediated transport#GO:0006891;organelle organization#GO:0006996;transport#GO:0006810;endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193 bounding membrane of organelle#GO:0098588;Golgi cisterna#GO:0031985;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;Golgi stack#GO:0005795;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791;Golgi membrane#GO:0000139 CIOIN|Ensembl=ENSCING00000007521.3|UniProtKB=F6UJ07 F6UJ07 PTHR16306:SF0 TRANSLIN-ASSOCIATED FACTOR X-INTERACTING PROTEIN 1 TRANSLIN-ASSOCIATED FACTOR X-INTERACTING PROTEIN 1 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000003656.3|UniProtKB=F7AXL0 F7AXL0 PTHR45857:SF4 FORMIN-LIKE PROTEIN FORMIN-LIKE PROTEIN CIOIN|Ensembl=ENSCING00000009650.3|UniProtKB=F6WVA9 F6WVA9 PTHR12002:SF116 CLAUDIN CLAUDIN-11-LIKE cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cell-cell junction organization#GO:0045216;cellular component biogenesis#GO:0044085;cell-cell junction assembly#GO:0007043;cell junction organization#GO:0034330;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;cell adhesion#GO:0007155;cellular process#GO:0009987 tight junction#GO:0070160;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cell junction#GO:0030054;bicellular tight junction#GO:0005923;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;apical junction complex#GO:0043296;plasma membrane#GO:0005886 cell junction protein#PC00070;tight junction#PC00214 CIOIN|Gene=CTM1|UniProtKB=Q07068 Q07068 CTM1 PTHR19269:SF45 TROPOMYOSIN TROPOMYOSIN-1, ISOFORMS 33_34 cytoskeletal protein#PC00085;actin binding motor protein#PC00040 CIOIN|Ensembl=ENSCING00000007203.3|UniProtKB=F6Y836 F6Y836 PTHR24082:SF509 NUCLEAR HORMONE RECEPTOR NUCLEAR RECEPTOR SUBFAMILY 1, GROUP H, MEMBER 3 cis-regulatory region sequence-specific DNA binding#GO:0000987;signaling receptor activity#GO:0038023;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular transducer activity#GO:0060089;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of nitrogen compound metabolic process#GO:0051173;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;positive regulation of RNA biosynthetic process#GO:1902680;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA-templated transcription#GO:0045892;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;positive regulation of biological process#GO:0048518;negative regulation of cellular process#GO:0048523;cellular developmental process#GO:0048869;negative regulation of biosynthetic process#GO:0009890;regulation of DNA-templated transcription#GO:0006355;negative regulation of metabolic process#GO:0009892;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;negative regulation of nitrogen compound metabolic process#GO:0051172;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;positive regulation of RNA metabolic process#GO:0051254;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C4 zinc finger nuclear receptor#PC00169;zinc finger transcription factor#PC00244 CIOIN|Ensembl=ENSCING00000002360.3|UniProtKB=F6RAB3 F6RAB3 PTHR10625:SF36 HISTONE DEACETYLASE HDAC1-RELATED HISTONE DEACETYLASE 3 histone modifying activity#GO:0140993;histone deacetylase activity#GO:0004407;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;deacetylase activity#GO:0019213;catalytic activity, acting on a protein#GO:0140096 protein-DNA complex organization#GO:0071824;cellular component organization#GO:0016043;cellular process#GO:0009987;epigenetic regulation of gene expression#GO:0040029;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;protein-containing complex organization#GO:0043933;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;chromatin remodeling#GO:0006338;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 Wnt signaling pathway#P00057>Histone deacetylase#P01472 CIOIN|Ensembl=ENSCING00000000389.3|UniProtKB=A0A1W2W3I8 A0A1W2W3I8 LOC100184108 PTHR10024:SF203 SYNAPTOTAGMIN C2 DOMAIN-CONTAINING PROTEIN cation binding#GO:0043169;small molecule binding#GO:0036094;binding#GO:0005488;phosphatidylserine binding#GO:0001786;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;protein binding#GO:0005515;clathrin binding#GO:0030276;lipid binding#GO:0008289;ion binding#GO:0043167;phospholipid binding#GO:0005543;SNARE binding#GO:0000149 localization#GO:0051179;regulated exocytosis#GO:0045055;exocytosis#GO:0006887;establishment of localization#GO:0051234;secretion#GO:0046903;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;calcium-ion regulated exocytosis#GO:0017156;export from cell#GO:0140352;secretion by cell#GO:0032940 intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;transport vesicle#GO:0030133;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 membrane trafficking regulatory protein#PC00151 CIOIN|Ensembl=ENSCING00000023348.1|UniProtKB=H2XWC1 H2XWC1 PTHR22811:SF184 TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN 10 vesicle coat protein#PC00235 CIOIN|Ensembl=ENSCING00000000320.3|UniProtKB=F6ZFI0 F6ZFI0 PTHR15508:SF8 RIBOSOMAL PROTEIN S6 KINASE LD24550P non-receptor serine/threonine protein kinase#PC00167 CIOIN|Ensembl=ENSCING00000021253.1|UniProtKB=H2Y2I6 H2Y2I6 PTHR31331:SF1 LCCL DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_5G08630) CYSTEINE RICH SECRETORY PROTEIN LCCL DOMAIN CONTAINING 2 CIOIN|Ensembl=ENSCING00000009247.3|UniProtKB=F6W0Z5 F6W0Z5 PTHR14191:SF27 PDZ DOMAIN CONTAINING PROTEIN MICROTUBULE ASSOCIATED SERINE_THREONINE KINASE FAMILY MEMBER 4 protein-membrane adaptor activity#GO:0043495;molecular adaptor activity#GO:0060090;protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102;protein-macromolecule adaptor activity#GO:0030674 localization#GO:0051179;protein localization to plasma membrane#GO:0072659;protein localization to cell periphery#GO:1990778;localization within membrane#GO:0051668;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;protein localization to membrane#GO:0072657;cellular process#GO:0009987;protein localization#GO:0008104 plasma membrane region#GO:0098590;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;apical part of cell#GO:0045177;plasma membrane#GO:0005886;apical plasma membrane#GO:0016324 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000016307.2|UniProtKB=F6X3P4 F6X3P4 PTHR43289:SF33 MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 20-RELATED SERINE_THREONINE KINASE 31 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;peptidyl-amino acid modification#GO:0018193;cellular process#GO:0009987;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;nitrogen compound metabolic process#GO:0006807;peptidyl-serine modification#GO:0018209;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000022239.1|UniProtKB=H2XUP4 H2XUP4 LOC100185800 PTHR43639:SF1 OXIDOREDUCTASE, SHORT-CHAIN DEHYDROGENASE/REDUCTASE FAMILY (AFU_ORTHOLOGUE AFUA_5G02870) SHORT-CHAIN DEHYDROGENASE_REDUCTASE FAMILY PROTEIN oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000015555.2|UniProtKB=F6SL89 F6SL89 PTHR43735:SF3 APOPTOSIS-INDUCING FACTOR 1 FERROPTOSIS SUPPRESSOR PROTEIN 1 nucleotide binding#GO:0000166;electron transfer activity#GO:0009055;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;flavin adenine dinucleotide binding#GO:0050660;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167;oxidoreductase activity#GO:0016491 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 p53 pathway#P00059>NOXA#G01572 CIOIN|Ensembl=ENSCING00000020178.1|UniProtKB=H2XM38 H2XM38 PTHR35252:SF1 RETINITIS PIGMENTOSA 9 PROTEIN RETINITIS PIGMENTOSA 9 PROTEIN CIOIN|Ensembl=ENSCING00000004898.3|UniProtKB=A0A1W3JNN9 A0A1W3JNN9 LOC100176025 PTHR24349:SF243 SERINE/THREONINE-PROTEIN KINASE CALCIUM_CALMODULIN-DEPENDENT PROTEIN KINASE TYPE IV transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;protein binding#GO:0005515;calmodulin binding#GO:0005516;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular process#GO:0009987;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 CCKR signaling map#P06959>CaMKIV#P07198 CIOIN|Ensembl=ENSCING00000018430.1|UniProtKB=H2XZI9 H2XZI9 LOC100186613 PTHR46830:SF1 TRANSFERASE, PUTATIVE-RELATED ALPHA-1,4-N-ACETYLGLUCOSAMINYLTRANSFERASE transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000010041.3|UniProtKB=F6QHL8 F6QHL8 LOC100182077 PTHR31882:SF11 TNFAIP3-INTERACTING PROTEIN COILED COIL FAMILY MEMBER HDA1 COMPLEX SUBUNIT 2 regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 CIOIN|Ensembl=ENSCING00000008795.3|UniProtKB=F6SCR3 F6SCR3 LOC100186431 PTHR12463:SF0 OXYGENASE-RELATED ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE ALKB HOMOLOG 4 demethylase activity#GO:0032451;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 oxygenase#PC00177 CIOIN|Ensembl=ENSCING00000016632.2|UniProtKB=F6PX18 F6PX18 PTHR22906:SF49 PROPERDIN COADHESIN-LIKE CIOIN|Ensembl=ENSCING00000019791.1|UniProtKB=H2XU53 H2XU53 PTHR19375:SF184 HEAT SHOCK PROTEIN 70KDA STRESS-70 PROTEIN, MITOCHONDRIAL Hsp70 family chaperone#PC00027 Parkinson disease#P00049>Hsp70#P01208 CIOIN|Ensembl=ENSCING00000020251.1|UniProtKB=H2XNG7 H2XNG7 LOC100178404 PTHR10036:SF3 CD59 GLYCOPROTEIN PROTEIN SLEEPLESS-RELATED CIOIN|Ensembl=ENSCING00000024585.1|UniProtKB=H2XR39 H2XR39 LOC100182094 PTHR19143:SF444 FIBRINOGEN/TENASCIN/ANGIOPOEITIN PROTEIN SCABROUS external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 CIOIN|Ensembl=ENSCING00000006639.3|UniProtKB=F6U176 F6U176 LOC100178524 PTHR46331:SF2 VALACYCLOVIR HYDROLASE VALACYCLOVIR HYDROLASE hydrolase activity#GO:0016787;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000006495.3|UniProtKB=F6Q119 F6Q119 hb3 PTHR46458:SF1 BLR2807 PROTEIN GEO09476P1 transporter#PC00227 CIOIN|Ensembl=ENSCING00000021943.1|UniProtKB=H2XTZ2 H2XTZ2 PTHR46780:SF9 PROTEIN EVA-1 D-GALACTOSIDE_L-RHAMNOSE BINDING SUEL LECTIN PROTEIN CIOIN|Ensembl=ENSCING00000023443.1|UniProtKB=F7ASG9 F7ASG9 PTHR24276:SF91 POLYSERASE-RELATED AT26814P-RELATED hydrolase activity#GO:0016787;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171 serine protease#PC00203;protease#PC00190 CIOIN|Ensembl=ENSCING00000005861.3|UniProtKB=F6UGT8 F6UGT8 LOC100183833 PTHR14845:SF5 COILED-COIL DOMAIN-CONTAINING 166 BASAL BODY-ORIENTATION FACTOR 1 CIOIN|Ensembl=ENSCING00000007816.3|UniProtKB=F6XC92 F6XC92 PTHR10527:SF5 IMPORTIN BETA IMPORTIN 5 signal sequence binding#GO:0005048;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277 cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;protein localization to nucleus#GO:0034504;nitrogen compound transport#GO:0071705;establishment of protein localization to organelle#GO:0072594;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;protein import into nucleus#GO:0006606;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;protein localization to organelle#GO:0033365;intracellular transport#GO:0046907;nuclear transport#GO:0051169;import into nucleus#GO:0051170 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transporter#PC00227 CIOIN|Ensembl=ENSCING00000002269.3|UniProtKB=F6W2I6 F6W2I6 PTHR31793:SF27 4-HYDROXYBENZOYL-COA THIOESTERASE FAMILY MEMBER NOVEL THIOESTERASE SUPERFAMILY DOMAIN AND SAPOSIN A-TYPE DOMAIN CONTAINING PROTEIN (0610012H03RIK) hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;fatty acyl-CoA hydrolase activity#GO:0047617;catalytic activity#GO:0003824;thiolester hydrolase activity#GO:0016790 esterase#PC00097;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000018107.1|UniProtKB=H2XZV8 H2XZV8 LOC100179616 PTHR11076:SF33 DNA REPAIR POLYMERASE UMUC / TRANSFERASE FAMILY MEMBER DNA POLYMERASE KAPPA DNA-directed DNA polymerase activity#GO:0003887;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on DNA#GO:0140097;DNA polymerase activity#GO:0034061 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;postreplication repair#GO:0006301;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;translesion synthesis#GO:0019985;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;nucleobase-containing compound biosynthetic process#GO:0034654;DNA biosynthetic process#GO:0071897;DNA synthesis involved in DNA repair#GO:0000731;aromatic compound biosynthetic process#GO:0019438;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259 DNA metabolism protein#PC00009 CIOIN|Ensembl=ENSCING00000012923.1|UniProtKB=F6RM44 F6RM44 LOC100178048 PTHR11955:SF156 FATTY ACID BINDING PROTEIN LIPOCALIN_CYTOSOLIC FATTY-ACID BINDING DOMAIN-CONTAINING PROTEIN fatty acid binding#GO:0005504;small molecule binding#GO:0036094;binding#GO:0005488;carboxylic acid binding#GO:0031406;lipid binding#GO:0008289;ion binding#GO:0043167;organic acid binding#GO:0043177;anion binding#GO:0043168 localization#GO:0051179;monocarboxylic acid transport#GO:0015718;organic substance transport#GO:0071702;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;organic anion transport#GO:0015711;fatty acid transport#GO:0015908;organic acid transport#GO:0015849;transport#GO:0006810;carboxylic acid transport#GO:0046942;lipid localization#GO:0010876;lipid transport#GO:0006869 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transfer/carrier protein#PC00219 CIOIN|Ensembl=ENSCING00000012271.2|UniProtKB=F6V9F0 F6V9F0 PTHR13693:SF2 CLASS II AMINOTRANSFERASE/8-AMINO-7-OXONONANOATE SYNTHASE SERINE PALMITOYLTRANSFERASE 1 palmitoyltransferase activity#GO:0016409;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824 organic hydroxy compound metabolic process#GO:1901615;lipid metabolic process#GO:0006629;alcohol biosynthetic process#GO:0046165;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic hydroxy compound biosynthetic process#GO:1901617;alcohol metabolic process#GO:0006066;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;membrane lipid biosynthetic process#GO:0046467;sphingolipid metabolic process#GO:0006665;primary metabolic process#GO:0044238;ceramide metabolic process#GO:0006672;amide biosynthetic process#GO:0043604;membrane lipid metabolic process#GO:0006643;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;ceramide biosynthetic process#GO:0046513;small molecule biosynthetic process#GO:0044283;cellular lipid metabolic process#GO:0044255;amide metabolic process#GO:0043603;sphingolipid biosynthetic process#GO:0030148;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transaminase#PC00216;transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000018967.1|UniProtKB=A0A1W5BBE3 A0A1W5BBE3 LOC100182428 PTHR24124:SF14 ANKYRIN REPEAT FAMILY A CHROMOSOME UNDETERMINED SCAFFOLD_25, WHOLE GENOME SHOTGUN SEQUENCE regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of biosynthetic process#GO:0009889;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein-binding activity modulator#PC00095 CIOIN|Ensembl=ENSCING00000022186.1|UniProtKB=H2XKN7 H2XKN7 PTHR12669:SF12 EUKARYOTIC TRANSLATION INITIATION FACTOR 4E-BINDING PROTEIN EUKARYOTIC TRANSLATION INITIATION FACTOR 4E-BINDING PROTEIN translation initiation factor binding#GO:0031369;protein binding#GO:0005515;binding#GO:0005488 negative regulation of gene expression#GO:0010629;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;negative regulation of biosynthetic process#GO:0009890;regulation of amide metabolic process#GO:0034248;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;regulation of translational initiation#GO:0006446;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of translation#GO:0017148;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;post-transcriptional regulation of gene expression#GO:0010608;biological regulation#GO:0065007;regulation of translation#GO:0006417;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 translation initiation factor#PC00224;translation factor#PC00223;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000018050.1|UniProtKB=H2Y245 H2Y245 PTHR11984:SF53 CONNEXIN GAP JUNCTION PROTEIN wide pore channel activity#GO:0022829;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;channel activity#GO:0015267 biological regulation#GO:0065007;regulation of biological process#GO:0050789;cell communication#GO:0007154;cellular process#GO:0009987;cell-cell signaling#GO:0007267;signaling#GO:0023052 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 cell junction protein#PC00070;gap junction#PC00105 CIOIN|Ensembl=ENSCING00000025035.1|UniProtKB=H2XMT7 H2XMT7 PTHR24099:SF15 E3 UBIQUITIN-PROTEIN LIGASE TRIM36-RELATED E3 UBIQUITIN-PROTEIN LIGASE TRIM9 ubiquitin-protein ligase#PC00234 CIOIN|Ensembl=ENSCING00000020536.1|UniProtKB=H2XS74 H2XS74 PTHR19969:SF8 SH2-SH3 ADAPTOR PROTEIN-RELATED ADAPTER MOLECULE CRK molecular adaptor activity#GO:0060090;signaling adaptor activity#GO:0035591;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;protein tyrosine kinase binding#GO:1990782;receptor tyrosine kinase binding#GO:0030971;signaling receptor binding#GO:0005102;kinase binding#GO:0019900 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cell motility#GO:0048870;cellular process#GO:0009987;cell migration#GO:0016477;signaling#GO:0023052 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 Integrin signalling pathway#P00034>Crk#P00933;CCKR signaling map#P06959>CRK#P07125;Angiogenesis#P00005>Crk#P00207 CIOIN|Ensembl=ENSCING00000004388.3|UniProtKB=F7AUJ3 F7AUJ3 MCM7 PTHR11630:SF26 DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER DNA REPLICATION LICENSING FACTOR MCM7 ATP-dependent activity, acting on DNA#GO:0008094;nucleic acid binding#GO:0003676;helicase activity#GO:0004386;ATP-dependent activity#GO:0140657;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;single-stranded DNA binding#GO:0003697;DNA binding#GO:0003677;catalytic activity, acting on a nucleic acid#GO:0140640;DNA helicase activity#GO:0003678;catalytic activity, acting on DNA#GO:0140097;single-stranded DNA helicase activity#GO:0017116 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;double-strand break repair#GO:0006302;nucleobase-containing compound metabolic process#GO:0006139;DNA geometric change#GO:0032392;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;recombinational repair#GO:0000725;DNA duplex unwinding#GO:0032508;DNA-templated DNA replication#GO:0006261;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;DNA unwinding involved in DNA replication#GO:0006268;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;double-strand break repair via homologous recombination#GO:0000724;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;DNA conformation change#GO:0071103;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;double-strand break repair via break-induced replication#GO:0000727;organelle organization#GO:0006996;chromosome organization#GO:0051276;cellular response to stress#GO:0033554;DNA replication#GO:0006260;DNA replication initiation#GO:0006270;DNA strand elongation involved in DNA replication#GO:0006271;DNA metabolic process#GO:0006259 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;MCM complex#GO:0042555;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA metabolism protein#PC00009 CIOIN|Ensembl=ENSCING00000005813.3|UniProtKB=F6WH63 F6WH63 LOC100181537 PTHR44598:SF2 JUNCTIONAL ADHESION MOLECULE C JUNCTIONAL ADHESION MOLECULE C cell adhesion molecule#PC00069 CIOIN|Ensembl=ENSCING00000003303.3|UniProtKB=F6W1I6 F6W1I6 PTHR24093:SF369 CATION TRANSPORTING ATPASE CALCIUM-TRANSPORTING ATPASE calcium ion transmembrane transporter activity#GO:0015085;inorganic molecular entity transmembrane transporter activity#GO:0015318;transmembrane transporter activity#GO:0022857;primary active transmembrane transporter activity#GO:0015399;ATP-dependent activity#GO:0140657;metal ion transmembrane transporter activity#GO:0046873;active monoatomic ion transmembrane transporter activity#GO:0022853;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;P-type ion transporter activity#GO:0015662;ATPase-coupled transmembrane transporter activity#GO:0042626;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;inorganic cation transmembrane transporter activity#GO:0022890;active transmembrane transporter activity#GO:0022804;monoatomic ion transmembrane transporter activity#GO:0015075 intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;organelle#GO:0043226;intracellular organelle#GO:0043229;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 primary active transporter#PC00068;transporter#PC00227 CIOIN|Ensembl=ENSCING00000009938.3|UniProtKB=F6R5Y6 F6R5Y6 LOC100178687 PTHR11360:SF313 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER 13-LIKE ISOFORM X1 transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;monocarboxylic acid transmembrane transporter activity#GO:0008028;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215;organic acid transmembrane transporter activity#GO:0005342 localization#GO:0051179;monocarboxylic acid transport#GO:0015718;organic substance transport#GO:0071702;establishment of localization#GO:0051234;organic anion transport#GO:0015711;organic acid transport#GO:0015849;transport#GO:0006810;carboxylic acid transport#GO:0046942 basal plasma membrane#GO:0009925;basolateral plasma membrane#GO:0016323;plasma membrane region#GO:0098590;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;basal part of cell#GO:0045178;plasma membrane#GO:0005886 transporter#PC00227 CIOIN|Ensembl=ENSCING00000009535.3|UniProtKB=F6UXB3 F6UXB3 LOC100183241 PTHR47980:SF24 LD44762P IP08727P-RELATED GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824 cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;nitrogen compound transport#GO:0071705;protein secretion#GO:0009306;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;establishment of protein localization to extracellular region#GO:0035592;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;exocytosis#GO:0006887;establishment of localization#GO:0051234;secretion#GO:0046903;protein transport#GO:0015031;protein localization to extracellular region#GO:0071692;export from cell#GO:0140352;secretion by cell#GO:0032940 cellular anatomical entity#GO:0110165;membrane#GO:0016020 CIOIN|Ensembl=ENSCING00000020002.1|UniProtKB=H2XK39 H2XK39 PTHR23257:SF963 SERINE-THREONINE PROTEIN KINASE AT08303P transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000003479.3|UniProtKB=F7BHP4 F7BHP4 PTHR23073:SF12 26S PROTEASOME REGULATORY SUBUNIT 26S PROTEASOME REGULATORY SUBUNIT 8 ATP-dependent activity#GO:0140657 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 peptidase complex#GO:1905368;protein-containing complex#GO:0032991;proteasome accessory complex#GO:0022624;proteasome regulatory particle#GO:0005838;catalytic complex#GO:1902494;proteasome complex#GO:0000502;endopeptidase complex#GO:1905369;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 protease#PC00190;protein modifying enzyme#PC00260 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489 CIOIN|Ensembl=ENSCING00000007488.3|UniProtKB=F6XWG9 F6XWG9 PTHR24067:SF154 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 G2 ubiquitin-like protein conjugating enzyme activity#GO:0061650;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin conjugating enzyme activity#GO:0061631;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;protein polyubiquitination#GO:0000209;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 Parkinson disease#P00049>Ubc7#P01220;Ubiquitin proteasome pathway#P00060>E2#P01491 CIOIN|Ensembl=ENSCING00000021254.1|UniProtKB=H2XN11 H2XN11 PTHR24006:SF758 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 36 cysteine-type peptidase activity#GO:0008234;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;cysteine-type deubiquitinase activity#GO:0004843 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;protein modification by small protein removal#GO:0070646;protein deubiquitination#GO:0016579;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;post-translational protein modification#GO:0043687;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cysteine protease#PC00081;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000023809.1|UniProtKB=H2XZJ1 H2XZJ1 LOC113474068 PTHR13568:SF4 FAM11A, B PROTEIN TRANSMEMBRANE PROTEIN 60 CIOIN|Ensembl=ENSCING00000001164.3|UniProtKB=F6WBA4 F6WBA4 LOC100185972 PTHR10571:SF0 UDP-N-ACETYLGLUCOSAMINE--DOLICHYL-PHOSPHATE N-ACETYLGLUCOSAMINEPHOSPHOTRANSFERASE UDP-N-ACETYLGLUCOSAMINE--DOLICHYL-PHOSPHATE N-ACETYLGLUCOSAMINEPHOSPHOTRANSFERASE transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular anatomical entity#GO:0110165;membrane#GO:0016020 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000002059.2|UniProtKB=F6TFY3 F6TFY3 LOC100183452 PTHR11071:SF561 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE D-RELATED peptidyl-prolyl cis-trans isomerase activity#GO:0003755;isomerase activity#GO:0016853;catalytic activity, acting on a protein#GO:0140096;binding#GO:0005488;catalytic activity#GO:0003824;peptide binding#GO:0042277;amide binding#GO:0033218 macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein peptidyl-prolyl isomerization#GO:0000413;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein folding#GO:0006457;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 chaperone#PC00072 CIOIN|Ensembl=ENSCING00000000442.3|UniProtKB=A0A1W5BNW0 A0A1W5BNW0 LOC100185063 PTHR15151:SF13 PROTEIN EIGER ECTODYSPLASIN-A molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;protein binding#GO:0005515;signaling receptor binding#GO:0005102 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 CIOIN|Ensembl=ENSCING00000012308.2|UniProtKB=F7AVU6 F7AVU6 PTHR11132:SF250 SOLUTE CARRIER FAMILY 35 SOLUTE CARRIER FAMILY 35 MEMBER E3 carbohydrate derivative transmembrane transporter activity#GO:1901505;secondary active transmembrane transporter activity#GO:0015291;antiporter activity#GO:0015297;transmembrane transporter activity#GO:0022857;nucleobase-containing compound transmembrane transporter activity#GO:0015932;nucleotide-sugar transmembrane transporter activity#GO:0005338;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215 localization#GO:0051179;cellular process#GO:0009987;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000006547.3|UniProtKB=F6RPC5 F6RPC5 LOC100187507 PTHR13554:SF10 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 5-RELATED 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 5 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 protease#PC00190 CIOIN|Ensembl=ENSCING00000014176.2|UniProtKB=F7A7T9 F7A7T9 PTHR16165:SF5 NXPE FAMILY MEMBER NXPE FAMILY MEMBER 3 CIOIN|Ensembl=ENSCING00000005111.3|UniProtKB=F6WJV4 F6WJV4 PTHR32075:SF6 ISWI CHROMATIN-REMODELING COMPLEX SUBUNIT YPL216W-RELATED ISWI CHROMATIN-REMODELING COMPLEX SUBUNIT YPL216W-RELATED negative regulation of gene expression#GO:0010629;negative regulation of cellular metabolic process#GO:0031324;protein-DNA complex organization#GO:0071824;negative regulation of biological process#GO:0048519;telomere organization#GO:0032200;heterochromatin formation#GO:0031507;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of cellular process#GO:0048523;negative regulation of biosynthetic process#GO:0009890;cellular component organization#GO:0016043;negative regulation of metabolic process#GO:0009892;cellular process#GO:0009987;negative regulation of gene expression, epigenetic#GO:0045814;epigenetic regulation of gene expression#GO:0040029;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component organization or biogenesis#GO:0071840;regulation of cellular biosynthetic process#GO:0031326;heterochromatin organization#GO:0070828;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;protein-containing complex organization#GO:0043933;chromosome organization#GO:0051276;organelle organization#GO:0006996;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;chromatin organization#GO:0006325;chromatin remodeling#GO:0006338;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;negative regulation of cellular biosynthetic process#GO:0031327 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 CIOIN|Ensembl=ENSCING00000000592.3|UniProtKB=F6PX32 F6PX32 PTHR13723:SF281 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE PAPILIN metalloprotease#PC00153;protease#PC00190 CIOIN|Ensembl=ENSCING00000002670.3|UniProtKB=F6YD46 F6YD46 PTHR43836:SF2 CATECHOL O-METHYLTRANSFERASE 1-RELATED CATECHOL O-METHYLTRANSFERASE 1-RELATED methyltransferase activity#GO:0008168;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;O-methyltransferase activity#GO:0008171;catalytic activity#GO:0003824 methyltransferase#PC00155;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000020763.1|UniProtKB=H2XPS3 H2XPS3 PTHR24020:SF87 COLLAGEN ALPHA COLLAGEN ALPHA-1(VI) CHAIN-LIKE external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 CIOIN|Ensembl=ENSCING00000023996.1|UniProtKB=H2XPK8 H2XPK8 PTHR21220:SF0 DNA-DEPENDENT METALLOPROTEASE SPRTN DNA-DEPENDENT METALLOPROTEASE SPRTN protein binding#GO:0005515;binding#GO:0005488;polyubiquitin modification-dependent protein binding#GO:0031593;modification-dependent protein binding#GO:0140030 response to stimulus#GO:0050896;DNA damage response#GO:0006974;cellular response to stimulus#GO:0051716;response to stress#GO:0006950;cellular process#GO:0009987;cellular response to stress#GO:0033554 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000017547.2|UniProtKB=F6ZYZ9 F6ZYZ9 LOC100177098 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE SSU-1 sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824 cellular metabolic process#GO:0044237;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000002405.3|UniProtKB=F6RKY2 F6RKY2 PTHR12684:SF2 PUTATIVE PHOSPHOTRANSFERASE TRNA 2'-PHOSPHOTRANSFERASE 1 catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000012800.2|UniProtKB=F6WQA0 F6WQA0 PTHR16024:SF28 XK-RELATED PROTEIN XK-RELATED PROTEIN cellular anatomical entity#GO:0110165;membrane#GO:0016020 secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000017495.2|UniProtKB=L7N0S5 L7N0S5 PTHR43968:SF6 FAMILY NOT NAMED GLUTATHIONE S-TRANSFERASE OMEGA cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000019087.1|UniProtKB=H2Y0M8 H2Y0M8 PTHR11003:SF291 POTASSIUM CHANNEL, SUBFAMILY K IP11374P monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated potassium channel activity#GO:0005249;channel activity#GO:0015267;transporter activity#GO:0005215;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;regulation of membrane potential#GO:0042391;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;localization#GO:0051179;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;monoatomic cation transport#GO:0006812;potassium ion transmembrane transport#GO:0071805;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;potassium ion transport#GO:0006813 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 CIOIN|Ensembl=ENSCING00000022081.1|UniProtKB=H2XLQ7 H2XLQ7 LOC100175162 PTHR15459:SF3 POLYAMINE-MODULATED FACTOR 1 POLYAMINE-MODULATED FACTOR 1 cell cycle process#GO:0022402;cell cycle#GO:0007049;cellular process#GO:0009987;chromosome segregation#GO:0007059 supramolecular complex#GO:0099080;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;outer kinetochore#GO:0000940;protein-containing complex#GO:0032991;kinetochore#GO:0000776;chromosome#GO:0005694;condensed chromosome#GO:0000793;condensed chromosome, centromeric region#GO:0000779;chromosome, centromeric region#GO:0000775;chromosomal region#GO:0098687;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000007635.3|UniProtKB=F6WIM7 F6WIM7 PTHR24064:SF577 SOLUTE CARRIER FAMILY 22 MEMBER GH09241P secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000009016.3|UniProtKB=F6RC45 F6RC45 PTHR45692:SF1 G_PROTEIN_RECEP_F2_4 DOMAIN-CONTAINING PROTEIN G-PROTEIN COUPLED RECEPTORS FAMILY 2 PROFILE 2 DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000009506.2|UniProtKB=H2XPB7 H2XPB7 LOC100179300 PTHR34524:SF6 CALCYPHOSIN CALCYPHOSINE LIKE calmodulin-related#PC00061 CIOIN|Ensembl=ENSCING00000002156.3|UniProtKB=F6QGB1 F6QGB1 PTHR47330:SF1 POLY(U)-BINDING-SPLICING FACTOR PUF60-B-RELATED POLY(U)-BINDING-SPLICING FACTOR PUF60 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;RNA processing#GO:0006396;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;protein-RNA complex assembly#GO:0022618;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;alternative mRNA splicing, via spliceosome#GO:0000380;regulation of mRNA processing#GO:0050684;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular component organization#GO:0016043;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;mRNA splice site recognition#GO:0006376;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;regulation of RNA splicing#GO:0043484;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;protein-containing complex organization#GO:0043933;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;ribonucleoprotein complex biogenesis#GO:0022613;biological regulation#GO:0065007;mRNA processing#GO:0006397;protein-RNA complex organization#GO:0071826;RNA splicing, via transesterification reactions#GO:0000375;spliceosomal complex assembly#GO:0000245;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;regulation of metabolic process#GO:0019222;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323 ribonucleoprotein complex#GO:1990904;catalytic step 2 spliceosome#GO:0071013;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;precatalytic spliceosome#GO:0071011;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622 RNA splicing factor#PC00148;RNA processing factor#PC00147 CIOIN|Ensembl=ENSCING00000020545.1|UniProtKB=H2XNZ0 H2XNZ0 PTHR10627:SF31 SCP160 DODECA-SATELLITE-BINDING PROTEIN 1, ISOFORM A nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000003434.3|UniProtKB=F6XL66 F6XL66 PTHR12601:SF6 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT EIF-3 CLUSTERED MITOCHONDRIA PROTEIN HOMOLOG cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 translation initiation factor#PC00224;translation factor#PC00223;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000005972.2|UniProtKB=F6VTY2 F6VTY2 LOC100178357 PTHR31978:SF1 INTRAFLAGELLAR TRANSPORT PROTEIN 20 HOMOLOG INTRAFLAGELLAR TRANSPORT PROTEIN 20 HOMOLOG cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;cilium assembly#GO:0060271;cell projection organization#GO:0030030;macromolecule localization#GO:0033036;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031;protein localization#GO:0008104;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;protein localization to cilium#GO:0061512;organelle organization#GO:0006996;protein localization to organelle#GO:0033365;plasma membrane bounded cell projection assembly#GO:0120031 microtubule organizing center#GO:0005815;non-motile cilium#GO:0097730;ciliary base#GO:0097546;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;ciliary basal body#GO:0036064;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;cell projection#GO:0042995;cilium#GO:0005929;intraciliary transport particle#GO:0030990 CIOIN|Ensembl=ENSCING00000012489.2|UniProtKB=F6U5L2 F6U5L2 PTHR22765:SF403 RING FINGER AND PROTEASE ASSOCIATED DOMAIN-CONTAINING RING-TYPE DOMAIN-CONTAINING PROTEIN transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000020629.1|UniProtKB=H2XQG4 H2XQG4 PTHR24253:SF176 TRANSMEMBRANE PROTEASE SERINE CORIN, ISOFORM B serine protease#PC00203;protease#PC00190 CIOIN|Ensembl=ENSCING00000013257.2|UniProtKB=F6SFR5 F6SFR5 LOC100186148 PTHR28651:SF1 TRANSMEMBRANE PROTEIN 232 TRANSMEMBRANE PROTEIN 232 CIOIN|Ensembl=ENSCING00000006282.3|UniProtKB=F6V0N3 F6V0N3 PTHR45620:SF1 PDF RECEPTOR-LIKE PROTEIN-RELATED G-PROTEIN COUPLED RECEPTORS FAMILY 2 PROFILE 2 DOMAIN-CONTAINING PROTEIN signaling receptor activity#GO:0038023;peptide hormone binding#GO:0017046;binding#GO:0005488;peptide binding#GO:0042277;amide binding#GO:0033218;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled peptide receptor activity#GO:0008528;hormone binding#GO:0042562;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 CIOIN|Ensembl=ENSCING00000007746.3|UniProtKB=F6YZZ7 F6YZZ7 PTHR11255:SF48 DIACYLGLYCEROL KINASE DIACYLGLYCEROL KINASE 1 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301;lipid kinase activity#GO:0001727 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 transferase#PC00220;kinase#PC00137;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000009407.3|UniProtKB=F6U9L3 F6U9L3 PTHR10649:SF12 ARYL HYDROCARBON RECEPTOR SPINELESS, ISOFORM C sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;signaling receptor activity#GO:0038023;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;molecular transducer activity#GO:0060089;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 receptor complex#GO:0043235;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 basic helix-loop-helix transcription factor#PC00055 CIOIN|Ensembl=ENSCING00000022840.1|UniProtKB=H2Y3S0 H2Y3S0 LOC100182496 PTHR36978:SF4 P-LOOP CONTAINING NUCLEOTIDE TRIPHOSPHATE HYDROLASE P-LOOP CONTAINING NUCLEOSIDE TRIPHOSPHATE HYDROLASE PROTEIN metabolite interconversion enzyme#PC00262;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000002090.3|UniProtKB=F7AA36 F7AA36 LOC100185700 PTHR24183:SF1 FIBRONECTIN TYPE 3 AND ANKYRIN REPEAT DOMAINS PROTEIN 1 FIBRONECTIN TYPE 3 AND ANKYRIN REPEAT DOMAINS PROTEIN 1 regulation of apoptotic process#GO:0042981;regulation of DNA-binding transcription factor activity#GO:0051090;regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;positive regulation of molecular function#GO:0044093;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-binding transcription factor activity#GO:0051091;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of programmed cell death#GO:0043067;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000007755.3|UniProtKB=F6XU45 F6XU45 LOC100184889 PTHR13306:SF6 TRANSMEMBRANE PROTEIN 138 TRANSMEMBRANE PROTEIN 138 membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;cilium#GO:0005929;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025 CIOIN|Ensembl=ENSCING00000003340.3|UniProtKB=F6S1S7 F6S1S7 LOC100182193 PTHR24073:SF858 DRAB5-RELATED DRAB5 GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824 localization#GO:0051179;organic substance transport#GO:0071702;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;transport#GO:0006810;protein transport#GO:0015031;nitrogen compound transport#GO:0071705;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104 cytoplasm#GO:0005737;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular vesicle#GO:0097708;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endocytic vesicle#GO:0030139;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 small GTPase#PC00208;G-protein#PC00020 CIOIN|Ensembl=ENSCING00000016657.2|UniProtKB=F6Z4J5 F6Z4J5 LOC100179530 PTHR22802:SF379 C-TYPE LECTIN SUPERFAMILY MEMBER CHONDROITIN SULFATE PROTEOGLYCAN 2 ISOFORM X1 membrane traffic protein#PC00150 CIOIN|Ensembl=ENSCING00000003556.3|UniProtKB=F6YT91 F6YT91 PTHR31057:SF0 E3 UFM1-PROTEIN LIGASE 1 E3 UFM1-PROTEIN LIGASE 1 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824 regulation of protein metabolic process#GO:0051246;regulation of catabolic process#GO:0009894;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;protein modification process#GO:0036211;regulation of protein catabolic process#GO:0042176;regulation of proteolysis involved in protein catabolic process#GO:1903050;post-translational protein modification#GO:0043687;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;regulation of proteolysis#GO:0030162;cellular response to stimulus#GO:0051716;response to endoplasmic reticulum stress#GO:0034976;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular process#GO:0009987;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;regulation of proteasomal protein catabolic process#GO:0061136;response to stimulus#GO:0050896;response to stress#GO:0006950;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;cellular response to stress#GO:0033554;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434;regulation of metabolic process#GO:0019222 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000021114.1|UniProtKB=H2Y2C6 H2Y2C6 PTHR10972:SF205 OXYSTEROL-BINDING PROTEIN-RELATED OXYSTEROL-BINDING PROTEIN 1 binding#GO:0005488;organic cyclic compound binding#GO:0097159;steroid binding#GO:0005496;sterol transporter activity#GO:0015248;sterol binding#GO:0032934;lipid binding#GO:0008289;lipid transporter activity#GO:0005319;transporter activity#GO:0005215 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;membrane#GO:0016020;intracellular anatomical structure#GO:0005622 transfer/carrier protein#PC00219 CIOIN|Ensembl=ENSCING00000005959.3|UniProtKB=F6XHG6 F6XHG6 PTHR10151:SF114 ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE ECTONUCLEOTIDE PYROPHOSPHATASE_PHOSPHODIESTERASE C27A7.3 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000011893.2|UniProtKB=F6W426 F6W426 PTHR20905:SF1 N-ACETYLTRANSFERASE-RELATED AT07410P-RELATED acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;N-acetyltransferase activity#GO:0008080;acyltransferase activity#GO:0016746;acetyltransferase activity#GO:0016407;catalytic activity#GO:0003824;N-acyltransferase activity#GO:0016410 acetyltransferase#PC00038 CIOIN|Ensembl=ENSCING00000007568.3|UniProtKB=F7AMH0 F7AMH0 LOC100176561 PTHR19848:SF0 WD40 REPEAT PROTEIN NOTCHLESS PROTEIN HOMOLOG 1 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;cellular process#GO:0009987;ribosomal large subunit biogenesis#GO:0042273;organelle assembly#GO:0070925;protein-RNA complex assembly#GO:0022618;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;organelle organization#GO:0006996;ribosomal large subunit assembly#GO:0000027;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;protein-RNA complex organization#GO:0071826;non-membrane-bounded organelle assembly#GO:0140694 membrane-enclosed lumen#GO:0031974;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000014976.2|UniProtKB=F6S0Y6 F6S0Y6 zf(c2h2)-23 PTHR23235:SF150 KRUEPPEL-LIKE TRANSCRIPTION FACTOR KRUEPPEL-LIKE FACTOR LUNA sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 CIOIN|Ensembl=ENSCING00000015591.2|UniProtKB=F6ZKQ1 F6ZKQ1 PTHR31393:SF2 C5ORF31 CHROMOSOME 7 OPEN READING FRAME 31 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;centrosome#GO:0005813 CIOIN|Ensembl=ENSCING00000011456.2|UniProtKB=F6ZUH0 F6ZUH0 LOC100186760 PTHR13568:SF6 FAM11A, B PROTEIN TRANSMEMBRANE PROTEIN 185A CIOIN|Ensembl=ENSCING00000003432.3|UniProtKB=F6XLA1 F6XLA1 PTHR13793:SF107 PHD FINGER PROTEINS BROMODOMAIN-CONTAINING PROTEIN HOMOLOG regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 zinc finger transcription factor#PC00244 CIOIN|Ensembl=ENSCING00000021439.1|UniProtKB=H2XYB3 H2XYB3 PTHR24221:SF654 ATP-BINDING CASSETTE SUB-FAMILY B ATP-BINDING CASSETTE SUB-FAMILY B MEMBER 6 transmembrane transporter activity#GO:0022857;primary active transmembrane transporter activity#GO:0015399;ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 localization#GO:0051179;establishment of localization#GO:0051234;cellular process#GO:0009987;transmembrane transport#GO:0055085;transport#GO:0006810 ATP-binding cassette (ABC) transporter#PC00003;transporter#PC00227 CIOIN|Ensembl=ENSCING00000009759.3|UniProtKB=F7ABC0 F7ABC0 PTHR10110:SF86 SODIUM/HYDROGEN EXCHANGER SODIUM_HYDROGEN EXCHANGER 7 secondary active transmembrane transporter activity#GO:0015291;inorganic molecular entity transmembrane transporter activity#GO:0015318;antiporter activity#GO:0015297;transmembrane transporter activity#GO:0022857;potassium ion transmembrane transporter activity#GO:0015079;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;proton transmembrane transporter activity#GO:0015078;metal cation:proton antiporter activity#GO:0051139;active monoatomic ion transmembrane transporter activity#GO:0022853;monoatomic cation transmembrane transporter activity#GO:0008324;monoatomic ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;inorganic cation transmembrane transporter activity#GO:0022890;transporter activity#GO:0005215 regulation of intracellular pH#GO:0051453;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;homeostatic process#GO:0042592;inorganic ion transmembrane transport#GO:0098660;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;cellular process#GO:0009987;intracellular chemical homeostasis#GO:0055082;monoatomic ion homeostasis#GO:0050801;localization#GO:0051179;regulation of pH#GO:0006885;import across plasma membrane#GO:0098739;sodium ion transport#GO:0006814;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;intracellular monoatomic cation homeostasis#GO:0030003;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;monoatomic cation transport#GO:0006812;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion transport#GO:0006811;regulation of cellular pH#GO:0030641;import into cell#GO:0098657;monoatomic cation transmembrane transport#GO:0098655;sodium ion transmembrane transport#GO:0035725;potassium ion transport#GO:0006813 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000007119.3|UniProtKB=F6SWB6 F6SWB6 PTHR12447:SF25 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 13 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 13C cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000018222.1|UniProtKB=H2XSX6 H2XSX6 PTHR12133:SF2 TRNA (ADENINE(58)-N(1))-METHYLTRANSFERASE TRNA (ADENINE(58)-N(1))-METHYLTRANSFERASE CATALYTIC SUBUNIT TRMT61A cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA modification#GO:0009451;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;tRNA modification#GO:0006400;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;macromolecule methylation#GO:0043414;tRNA methylation#GO:0030488;organic cyclic compound metabolic process#GO:1901360;methylation#GO:0032259;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;RNA methylation#GO:0001510;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 methyltransferase complex#GO:0034708;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031;RNA methyltransferase#PC00033 CIOIN|Ensembl=ENSCING00000018028.1|UniProtKB=H2Y192 H2Y192 PTHR22906:SF43 PROPERDIN PROPERDIN CIOIN|Ensembl=ENSCING00000007303.3|UniProtKB=F6S7F2 F6S7F2 MED16 PTHR13224:SF6 THYROID HORMONE RECEPTOR-ASSOCIATED PROTEIN-RELATED MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 16 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of RNA biosynthetic process#GO:2001141;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of RNA metabolic process#GO:0051254;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;mediator complex#GO:0016592;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000005300.3|UniProtKB=F6RUV6 F6RUV6 LOC100176751 PTHR15157:SF5 UV RADIATION RESISTANCE-ASSOCIATED GENE PROTEIN UV RADIATION RESISTANCE-ASSOCIATED GENE PROTEIN protein binding#GO:0005515;binding#GO:0005488;SNARE binding#GO:0000149 vesicle fusion#GO:0006906;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;transport#GO:0006810;protein-containing complex assembly#GO:0065003;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;membrane fusion#GO:0061025;establishment of localization#GO:0051234;protein-containing complex organization#GO:0043933;organelle organization#GO:0006996;vesicle organization#GO:0016050;organelle fusion#GO:0048284 cytoplasm#GO:0005737;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular vesicle#GO:0097708;vacuole#GO:0005773;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;lytic vacuole#GO:0000323;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000002799.3|UniProtKB=F6XMT2 F6XMT2 PTHR13533:SF1 N-ACETYLNEURAMINATE 9-O-ACETYLTRANSFERASE N-ACETYLNEURAMINATE 9-O-ACETYLTRANSFERASE acetyltransferase#PC00038 CIOIN|Ensembl=ENSCING00000009372.4|UniProtKB=F6WXT4 F6WXT4 LOC100175824 PTHR42908:SF6 TRANSLATION ELONGATION FACTOR-RELATED 116 KDA U5 SMALL NUCLEAR RIBONUCLEOPROTEIN COMPONENT GTPase activity#GO:0003924;nucleic acid binding#GO:0003676;binding#GO:0005488;catalytic activity#GO:0003824;snRNA binding#GO:0017069;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;translation regulator activity#GO:0045182;RNA binding#GO:0003723;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;translation regulator activity, nucleic acid binding#GO:0090079;translation elongation factor activity#GO:0003746;translation factor activity, RNA binding#GO:0008135 cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;peptide metabolic process#GO:0006518;RNA processing#GO:0006396;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;translation#GO:0006412;organic cyclic compound metabolic process#GO:1901360;mRNA metabolic process#GO:0016071;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;nucleic acid metabolic process#GO:0090304;peptide biosynthetic process#GO:0043043;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;translational elongation#GO:0006414 catalytic step 2 spliceosome#GO:0071013;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;U4/U6 x U5 tri-snRNP complex#GO:0046540;cytosol#GO:0005829;U2-type spliceosomal complex#GO:0005684;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;spliceosomal snRNP complex#GO:0097525;small nuclear ribonucleoprotein complex#GO:0030532;protein-containing complex#GO:0032991;spliceosomal tri-snRNP complex#GO:0097526;membrane-bounded organelle#GO:0043227;Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513 translation elongation factor#PC00222 CIOIN|Ensembl=ENSCING00000003016.3|UniProtKB=F6QBM2 F6QBM2 LOC100179323 PTHR24075:SF0 SEC63 DOMAIN-CONTAINING TRANSLOCATION PROTEIN SEC63 HOMOLOG protein transmembrane transporter activity#GO:0008320;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;binding#GO:0005488;organic cyclic compound binding#GO:0097159 localization within membrane#GO:0051668;cotranslational protein targeting to membrane#GO:0006613;cellular localization#GO:0051641;protein localization to endoplasmic reticulum#GO:0070972;macromolecule localization#GO:0033036;protein localization to membrane#GO:0072657;protein targeting#GO:0006605;protein targeting to ER#GO:0045047;establishment of protein localization to organelle#GO:0072594;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;SRP-dependent cotranslational protein targeting to membrane#GO:0006614;establishment of protein localization to membrane#GO:0090150;post-translational protein targeting to endoplasmic reticulum membrane#GO:0006620;protein targeting to membrane#GO:0006612;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein localization to organelle#GO:0033365;establishment of protein localization to endoplasmic reticulum#GO:0072599 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;endoplasmic reticulum protein-containing complex#GO:0140534;rough endoplasmic reticulum membrane#GO:0030867;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;rough endoplasmic reticulum#GO:0005791;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000001710.3|UniProtKB=F7BLG0 F7BLG0 PTHR46026:SF1 RHO-TYPE GUANINE NUCLEOTIDE EXCHANGE FACTOR, ISOFORM F RHO-TYPE GUANINE NUCLEOTIDE EXCHANGE FACTOR, ISOFORM F guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 CIOIN|Ensembl=ENSCING00000003237.3|UniProtKB=F6ZP02 F6ZP02 PTHR23142:SF1 PRE-MRNA-SPLICING FACTOR 38A-RELATED PRE-MRNA-SPLICING FACTOR 38A ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;precatalytic spliceosome#GO:0071011;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000012611.2|UniProtKB=F6XEK2 F6XEK2 LOC100185131 PTHR12461:SF42 HYPOXIA-INDUCIBLE FACTOR 1 ALPHA INHIBITOR-RELATED JMJC DOMAIN-CONTAINING PROTEIN protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000017599.2|UniProtKB=F6ZF76 F6ZF76 LOC100175853 PTHR14154:SF3 UPF0041 BRAIN PROTEIN 44-RELATED MITOCHONDRIAL PYRUVATE CARRIER transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;monocarboxylic acid transmembrane transporter activity#GO:0008028;organic anion transmembrane transporter activity#GO:0008514;organic acid transmembrane transporter activity#GO:0005342;transporter activity#GO:0005215 localization#GO:0051179;mitochondrial transport#GO:0006839;organic substance transport#GO:0071702;monocarboxylic acid transport#GO:0015718;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;organic anion transport#GO:0015711;organic acid transport#GO:0015849;transport#GO:0006810;carboxylic acid transport#GO:0046942;organic acid transmembrane transport#GO:1903825;cellular process#GO:0009987;mitochondrial transmembrane transport#GO:1990542;carboxylic acid transmembrane transport#GO:1905039 envelope#GO:0031975;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;organelle membrane#GO:0031090;organelle inner membrane#GO:0019866;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227 CIOIN|Ensembl=ENSCING00000005688|UniProtKB=Q8T888 Q8T888 DNAL1 PTHR15454:SF73 NISCHARIN RELATED DYNEIN AXONEMAL LIGHT CHAIN 1 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000007274.3|UniProtKB=F6SUT6 F6SUT6 PTHR13723:SF311 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE ADAM CYSTEINE-RICH DOMAIN-CONTAINING PROTEIN hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular component organization or biogenesis#GO:0071840;extracellular structure organization#GO:0043062;external encapsulating structure organization#GO:0045229;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;cellular component organization#GO:0016043;cellular process#GO:0009987;protein metabolic process#GO:0019538;extracellular matrix organization#GO:0030198;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944 metalloprotease#PC00153;protease#PC00190 CIOIN|Ensembl=ENSCING00000021658.1|UniProtKB=F6QDM2 F6QDM2 PTHR11571:SF230 GLUTATHIONE S-TRANSFERASE GLUTATHIONE TRANSFERASE glutathione transferase activity#GO:0004364;transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824 sulfur compound metabolic process#GO:0006790;nitrogen compound metabolic process#GO:0006807;peptide metabolic process#GO:0006518;cellular modified amino acid metabolic process#GO:0006575;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular process#GO:0009987;glutathione metabolic process#GO:0006749;amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000003877.3|UniProtKB=F6XGK4 F6XGK4 PTHR48033:SF10 RNA-BINDING (RRM/RBD/RNP MOTIFS) FAMILY PROTEIN RNA-BINDING PROTEIN SQUID nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of biosynthetic process#GO:0009889;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000003873.3|UniProtKB=F6T9M1 F6T9M1 LOC100184190 PTHR23073:SF155 26S PROTEASOME REGULATORY SUBUNIT 26S PROTEASOME REGULATORY SUBUNIT 6B ATP-dependent activity#GO:0140657 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 peptidase complex#GO:1905368;protein-containing complex#GO:0032991;proteasome accessory complex#GO:0022624;proteasome regulatory particle#GO:0005838;catalytic complex#GO:1902494;proteasome complex#GO:0000502;endopeptidase complex#GO:1905369;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 protease#PC00190;protein modifying enzyme#PC00260 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489;Ubiquitin proteasome pathway#P00060>19S proteasome#P01494 CIOIN|Ensembl=ENSCING00000004303.3|UniProtKB=F6TSM0 F6TSM0 PTHR15574:SF21 WD REPEAT DOMAIN-CONTAINING FAMILY DDB1- AND CUL4-ASSOCIATED FACTOR 8 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;cullin-RING ubiquitin ligase complex#GO:0031461;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;Cul4-RING E3 ubiquitin ligase complex#GO:0080008;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000007430.3|UniProtKB=Q69HQ7 Q69HQ7 LOC494376 PTHR23050:SF518 CALCIUM BINDING PROTEIN AT16150P-RELATED cation binding#GO:0043169;small molecule binding#GO:0036094;molecular function regulator activity#GO:0098772;binding#GO:0005488;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;enzyme regulator activity#GO:0030234 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 calmodulin-related#PC00061 B cell activation#P00010>Calmodulin#P00375;Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Calmodulin#P00755;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Phosphorylase b kinase#P00716;T cell activation#P00053>Calmodulin#P01305 CIOIN|Ensembl=ENSCING00000003099.3|UniProtKB=F6PK93 F6PK93 LOC100184784 PTHR24304:SF4 CYTOCHROME P450 FAMILY 7 CYTOCHROME P450 steroid hydroxylase activity#GO:0008395;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497 organic acid biosynthetic process#GO:0016053;organic hydroxy compound metabolic process#GO:1901615;oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;monocarboxylic acid biosynthetic process#GO:0072330;cellular metabolic process#GO:0044237;homeostatic process#GO:0042592;cellular biosynthetic process#GO:0044249;organic hydroxy compound biosynthetic process#GO:1901617;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;chemical homeostasis#GO:0048878;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;organic acid metabolic process#GO:0006082;cholesterol homeostasis#GO:0042632;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;steroid metabolic process#GO:0008202;organic cyclic compound metabolic process#GO:1901360;lipid homeostasis#GO:0055088;small molecule biosynthetic process#GO:0044283;carboxylic acid metabolic process#GO:0019752;steroid biosynthetic process#GO:0006694;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 oxygenase#PC00177;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000002114.3|UniProtKB=F6WS10 F6WS10 LOC100175701 PTHR10857:SF102 COPINE C2 DOMAIN-CONTAINING PROTEIN lipid binding#GO:0008289;phospholipid binding#GO:0005543;binding#GO:0005488 response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;cellular process#GO:0009987;response to chemical#GO:0042221 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 calcium-binding protein#PC00060 CIOIN|Ensembl=ENSCING00000005491.3|UniProtKB=F6S5L9 F6S5L9 PTHR10654:SF18 CAS SCAFFOLDING PROTEIN IP17195P regulation of biological process#GO:0050789;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cell motility#GO:0048870;cellular process#GO:0009987;cell migration#GO:0016477;signaling#GO:0023052;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 CIOIN|Ensembl=ENSCING00000013592.2|UniProtKB=F6VPK5 F6VPK5 PTHR45695:SF34 LEUCOKININ RECEPTOR-RELATED GALANIN RECEPTOR 2B-LIKE signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 CIOIN|Ensembl=ENSCING00000017152.2|UniProtKB=F6TQZ3 F6TQZ3 LOC100175055 PTHR15825:SF0 UBIQUITIN-FOLD MODIFIER 1 UBIQUITIN-FOLD MODIFIER 1 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;post-translational protein modification#GO:0043687;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000014177.2|UniProtKB=F7A7T2 F7A7T2 LOC100182675 PTHR47385:SF24 CALPONIN MUSCLE-SPECIFIC PROTEIN 20 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000009444.3|UniProtKB=F7BHB2 F7BHB2 PTHR11952:SF2 UDP- GLUCOSE PYROPHOSPHORYLASE LD24639P CIOIN|Ensembl=ENSCING00000023609.1|UniProtKB=H2Y2B5 H2Y2B5 LOC104265533 PTHR31184:SF2 HUNTINGTIN-INTERACTING PROTEIN K FAMILY MEMBER HUNTINGTIN-INTERACTING PROTEIN K regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of apoptotic process#GO:0042981;regulation of biological quality#GO:0065008;negative regulation of programmed cell death#GO:0043069;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of protein stability#GO:0031647;negative regulation of cellular process#GO:0048523;negative regulation of apoptotic process#GO:0043066;protein stabilization#GO:0050821;regulation of programmed cell death#GO:0043067 CIOIN|Ensembl=ENSCING00000011363.2|UniProtKB=F6U8R6 F6U8R6 LOC100179729 PTHR13659:SF5 AUTOSOMAL HIGHLY CONSERVED PROTEIN PROTEIN FAM8A1 CIOIN|Ensembl=ENSCING00000008279.3|UniProtKB=F6QHM7 F6QHM7 PTHR46768:SF1 TWO PORE CALCIUM CHANNEL PROTEIN 2 TWO PORE CHANNEL PROTEIN 2 monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;ligand-gated monoatomic cation channel activity#GO:0099094;sodium channel activity#GO:0005272;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;ligand-gated channel activity#GO:0022834 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;calcium-mediated signaling#GO:0019722;transport#GO:0006810;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cell communication#GO:0007154;cellular process#GO:0009987;localization#GO:0051179;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;establishment of localization#GO:0051234;regulation of cellular process#GO:0050794;biological process involved in interspecies interaction between organisms#GO:0044419;biological process involved in interaction with host#GO:0051701;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;intracellular signal transduction#GO:0035556;signaling#GO:0023052;import into cell#GO:0098657 bounding membrane of organelle#GO:0098588;lytic vacuole membrane#GO:0098852;intracellular membrane-bounded organelle#GO:0043231;vacuolar membrane#GO:0005774;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;lytic vacuole#GO:0000323;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;lysosomal membrane#GO:0005765;lysosome#GO:0005764;membrane-bounded organelle#GO:0043227 ion channel#PC00133;transporter#PC00227 CCKR signaling map#P06959>TPC1/2#P07209 CIOIN|Ensembl=ENSCING00000004269.3|UniProtKB=F6UH30 F6UH30 LOC100179963 PTHR42980:SF1 2-OXOISOVALERATE DEHYDROGENASE SUBUNIT BETA-RELATED 2-OXOISOVALERATE DEHYDROGENASE SUBUNIT BETA, MITOCHONDRIAL oxoacid metabolic process#GO:0043436;branched-chain amino acid metabolic process#GO:0009081;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;response to nutrient levels#GO:0031667;response to extracellular stimulus#GO:0009991;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;amino acid catabolic process#GO:0009063;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;response to chemical#GO:0042221;nitrogen compound metabolic process#GO:0006807;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;carboxylic acid metabolic process#GO:0019752;amino acid metabolic process#GO:0006520;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000002441.3|UniProtKB=E7FIY8 E7FIY8 nAChR PTHR18945:SF927 NEUROTRANSMITTER GATED ION CHANNEL ACETYLCHOLINE RECEPTOR SUBUNIT ALPHA-LIKE 1 transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;signaling receptor activity#GO:0038023;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;molecular transducer activity#GO:0060089;neurotransmitter receptor activity#GO:0030594;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267;monoatomic ion channel activity#GO:0005216;transporter activity#GO:0005215;ligand-gated channel activity#GO:0022834 transmembrane transport#GO:0055085;transport#GO:0006810;regulation of membrane potential#GO:0042391;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;localization#GO:0051179;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;synaptic signaling#GO:0099536;monoatomic ion transport#GO:0006811;signaling#GO:0023052;cell-cell signaling#GO:0007267 membrane protein complex#GO:0098796;synapse#GO:0045202;plasma membrane signaling receptor complex#GO:0098802;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;receptor complex#GO:0043235;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;neuron projection#GO:0043005;transmembrane transporter complex#GO:1902495;cell projection#GO:0042995;plasma membrane#GO:0005886 ligand-gated ion channel#PC00141;ion channel#PC00133;transporter#PC00227 Nicotinic acetylcholine receptor signaling pathway#P00044>alpha#P01088;Nicotinic acetylcholine receptor signaling pathway#P00044>nAChR#P01086 CIOIN|Ensembl=ENSCING00000021961.1|UniProtKB=H2XM11 H2XM11 LOC100177318 PTHR14917:SF4 SPERMATOGENESIS-ASSOCIATED PROTEIN 7 SPERMATOGENESIS-ASSOCIATED 7 microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cellular process#GO:0009987;microtubule-based process#GO:0007017;organelle organization#GO:0006996 axoneme#GO:0005930;microtubule organizing center#GO:0005815;cytoplasmic region#GO:0099568;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;ciliary basal body#GO:0036064;membrane-bounded organelle#GO:0043227;plasma membrane bounded cell projection cytoplasm#GO:0032838;ciliary plasm#GO:0097014;cell projection#GO:0042995;cytoskeleton#GO:0005856;cilium#GO:0005929 CIOIN|Ensembl=ENSCING00000000808.3|UniProtKB=F6RP84 F6RP84 irf-like-3 PTHR11949:SF53 INTERFERON REGULATORY FACTOR IRF TRYPTOPHAN PENTAD REPEAT DOMAIN-CONTAINING PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 CIOIN|Ensembl=ENSCING00000017376.2|UniProtKB=F6X0R0 F6X0R0 LOC100180259 PTHR10552:SF6 U2 SMALL NUCLEAR RIBONUCLEOPROTEIN A U2 SMALL NUCLEAR RIBONUCLEOPROTEIN A' RNA splicing factor#PC00148;RNA processing factor#PC00147 CIOIN|Ensembl=ENSCING00000022734.1|UniProtKB=H2XUI3 H2XUI3 PTHR12686:SF8 3'-5' EXORIBONUCLEASE CSL4-RELATED EXOSOME COMPLEX COMPONENT CSL4 RNA metabolism protein#PC00031;exoribonuclease#PC00099 CIOIN|Ensembl=ENSCING00000022073.1|UniProtKB=H2XX58 H2XX58 PTHR24161:SF103 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED LD20463P protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000003803.3|UniProtKB=F6ZTD1 F6ZTD1 PTHR11537:SF113 VOLTAGE-GATED POTASSIUM CHANNEL POTASSIUM VOLTAGE-GATED CHANNEL PROTEIN SHAKER monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;delayed rectifier potassium channel activity#GO:0005251;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated potassium channel activity#GO:0005249;transporter activity#GO:0005215;channel activity#GO:0015267;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated monoatomic ion channel activity#GO:0005244;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;regulation of membrane potential#GO:0042391;action potential#GO:0001508;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;localization#GO:0051179;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;monoatomic cation transport#GO:0006812;potassium ion transmembrane transport#GO:0071805;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;potassium ion transport#GO:0006813 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;voltage-gated potassium channel complex#GO:0008076;cation channel complex#GO:0034703;plasma membrane#GO:0005886 transporter#PC00227;voltage-gated ion channel#PC00241 CIOIN|Ensembl=ENSCING00000014113.2|UniProtKB=F6SRD6 F6SRD6 PTHR12327:SF0 ALPHA-TUBULIN N-ACETYLTRANSFERASE 1 ALPHA-TUBULIN N-ACETYLTRANSFERASE 1 transferase activity#GO:0016740;acyltransferase activity#GO:0016746;N-acetyltransferase activity#GO:0008080;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acetyltransferase activity#GO:0016407;peptide-lysine-N-acetyltransferase activity#GO:0061733;peptide N-acetyltransferase activity#GO:0034212;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;N-acyltransferase activity#GO:0016410 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;protein acylation#GO:0043543;protein metabolic process#GO:0019538;protein acetylation#GO:0006473;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 CIOIN|Ensembl=ENSCING00000010470.3|UniProtKB=F6QDM9 F6QDM9 PTHR11571:SF230 GLUTATHIONE S-TRANSFERASE GLUTATHIONE TRANSFERASE glutathione transferase activity#GO:0004364;transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824 sulfur compound metabolic process#GO:0006790;nitrogen compound metabolic process#GO:0006807;peptide metabolic process#GO:0006518;cellular modified amino acid metabolic process#GO:0006575;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular process#GO:0009987;glutathione metabolic process#GO:0006749;amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000004433.3|UniProtKB=F6USY0 F6USY0 PTHR24247:SF202 5-HYDROXYTRYPTAMINE RECEPTOR 5-HYDROXYTRYPTAMINE RECEPTOR 1 signaling receptor activity#GO:0038023;G protein-coupled amine receptor activity#GO:0008227;molecular transducer activity#GO:0060089;neurotransmitter receptor activity#GO:0030594;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;chemical synaptic transmission#GO:0007268;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;synaptic signaling#GO:0099536;trans-synaptic signaling#GO:0099537;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;cell-cell signaling#GO:0007267;signaling#GO:0023052 somatodendritic compartment#GO:0036477;neuron projection#GO:0043005;dendrite#GO:0030425;cell periphery#GO:0071944;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GsPCR#P00720 CIOIN|Ensembl=ENSCING00000000832.3|UniProtKB=F6R1K9 F6R1K9 LOC100176622 PTHR10556:SF37 3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE 3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE 2 oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 lipid metabolic process#GO:0006629;steroid metabolic process#GO:0008202;organic cyclic compound metabolic process#GO:1901360;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;lipid biosynthetic process#GO:0008610;steroid biosynthetic process#GO:0006694;metabolic process#GO:0008152;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704 dehydrogenase#PC00092;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000021024.1|UniProtKB=H2Y216 H2Y216 LOC100186437 PTHR10219:SF97 GLYCOLIPID TRANSFER PROTEIN-RELATED GLYCOLIPID TRANSFER PROTEIN lipid transfer activity#GO:0120013;small molecule binding#GO:0036094;binding#GO:0005488;amide binding#GO:0033218;phospholipid transporter activity#GO:0005548;lipid binding#GO:0008289;ion binding#GO:0043167;anion binding#GO:0043168;phospholipid binding#GO:0005543;transporter activity#GO:0005215;lipid transporter activity#GO:0005319 amide transport#GO:0042886;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;membrane organization#GO:0061024;transport#GO:0006810;nitrogen compound transport#GO:0071705;cellular component organization#GO:0016043;lipid localization#GO:0010876;intermembrane lipid transfer#GO:0120009;cellular process#GO:0009987;lipid transport#GO:0006869 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;membrane#GO:0016020;intracellular anatomical structure#GO:0005622 transfer/carrier protein#PC00219 CIOIN|Ensembl=ENSCING00000022286.1|UniProtKB=F6VWZ6 F6VWZ6 LOC100184554 PTHR13557:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 86 COILED-COIL DOMAIN-CONTAINING PROTEIN 86 intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000023441.1|UniProtKB=H2XM46 H2XM46 LOC100178383 PTHR12814:SF2 RNA-BINDING PROTEIN NOB1 RNA-BINDING PROTEIN NOB1 catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a nucleic acid#GO:0140640;endonuclease activity#GO:0004519;RNA nuclease activity#GO:0004540;RNA endonuclease activity#GO:0004521 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;maturation of SSU-rRNA#GO:0030490;ribosomal small subunit biogenesis#GO:0042274;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 preribosome, small subunit precursor#GO:0030688;ribonucleoprotein complex#GO:1990904;preribosome#GO:0030684;protein-containing complex#GO:0032991 CIOIN|Ensembl=ENSCING00000025148.1|UniProtKB=H2XNS1 H2XNS1 zf(c2h2)-40 PTHR15507:SF17 ZINC FINGER PROTEIN RLF C2H2-TYPE DOMAIN-CONTAINING PROTEIN nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 CIOIN|Ensembl=ENSCING00000002084.3|UniProtKB=F7AAH4 F7AAH4 PTHR10106:SF0 CYTOCHROME B561-RELATED LD36721P oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 reductase#PC00198;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000005656.3|UniProtKB=F6Y1X1 F6Y1X1 PTHR11923:SF51 SCAVENGER RECEPTOR CLASS B TYPE-1 SR-B1 LYSOSOME MEMBRANE PROTEIN 2 cargo receptor activity#GO:0038024 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 membrane trafficking regulatory protein#PC00151 CIOIN|Ensembl=ENSCING00000004570.3|UniProtKB=F6XCE2 F6XCE2 PTHR11675:SF68 N-ACETYLGALACTOSAMINYLTRANSFERASE N-ACETYLGALACTOSAMINYLTRANSFERASE 7 transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;UDP-glycosyltransferase activity#GO:0008194 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;protein O-linked glycosylation#GO:0006493;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000014023.2|UniProtKB=F6QVL5 F6QVL5 zf(u1like)-11 PTHR15491:SF9 FAMILY NOT NAMED CIP1-INTERACTING ZINC FINGER PROTEIN CIOIN|Ensembl=ENSCING00000006373.3|UniProtKB=F6RQZ5 F6RQZ5 LOC100181205 PTHR10050:SF51 DOLICHYL-PHOSPHATE-MANNOSE--PROTEIN MANNOSYLTRANSFERASE PROTEIN O-MANNOSYL-TRANSFERASE 1 mannosyltransferase activity#GO:0000030;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;protein O-linked glycosylation#GO:0006493;protein O-linked mannosylation#GO:0035269;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;protein mannosylation#GO:0035268;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085;mannosylation#GO:0097502 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000019652.1|UniProtKB=H2Y240 H2Y240 LOC100175013 PTHR12415:SF0 TYROSYL-DNA PHOSPHODIESTERASE 1 TYROSYL-DNA PHOSPHODIESTERASE 1 hydrolase activity, acting on ester bonds#GO:0016788;nucleic acid binding#GO:0003676;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;single-stranded DNA binding#GO:0003697;DNA binding#GO:0003677;hydrolase activity#GO:0016787;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on DNA#GO:0140097;double-stranded DNA binding#GO:0003690;phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;DNA damage response#GO:0006974;response to stress#GO:0006950;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular response to stress#GO:0033554;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 phosphodiesterase#PC00185;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000008250.3|UniProtKB=F6QZI8 F6QZI8 LOC100181007 PTHR46378:SF1 STEROL REGULATORY ELEMENT-BINDING PROTEIN CLEAVAGE-ACTIVATING PROTEIN STEROL REGULATORY ELEMENT-BINDING PROTEIN CLEAVAGE-ACTIVATING PROTEIN biological regulation#GO:0065007;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of lipid metabolic process#GO:0019216;regulation of lipid biosynthetic process#GO:0046890;regulation of biosynthetic process#GO:0009889;regulation of metabolic process#GO:0019222 membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 CIOIN|Ensembl=ENSCING00000004178.4|UniProtKB=F7BP62 F7BP62 PTHR12072:SF5 CWF19, CELL CYCLE CONTROL PROTEIN CWF19-LIKE PROTEIN 2 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;post-mRNA release spliceosomal complex#GO:0071014;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000014525.2|UniProtKB=F6QEY9 F6QEY9 PTHR10725:SF78 THAP DOMAIN-CONTAINING PROTEIN 9 DNA TRANSPOSASE THAP9 CIOIN|Ensembl=ENSCING00000008410.3|UniProtKB=F6XR36 F6XR36 PTHR24361:SF433 MITOGEN-ACTIVATED KINASE KINASE KINASE PROTEIN KINASE DOMAIN-CONTAINING PROTEIN transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 EGF receptor signaling pathway#P00018>MEKK1-5#P00553 CIOIN|Ensembl=ENSCING00000005718.3|UniProtKB=F6U2Y7 F6U2Y7 PTHR11304:SF29 EPHRIN EPHRIN protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 neuron projection guidance#GO:0097485;signal transduction#GO:0007165;neurogenesis#GO:0022008;cell projection organization#GO:0030030;developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cellular anatomical entity morphogenesis#GO:0032989;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;axon guidance#GO:0007411;anatomical structure morphogenesis#GO:0009653;neuron differentiation#GO:0030182;axonogenesis#GO:0007409;plasma membrane bounded cell projection morphogenesis#GO:0120039;signaling#GO:0023052;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;multicellular organism development#GO:0007275;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;cell communication#GO:0007154;cellular process#GO:0009987;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;neuron projection development#GO:0031175;axon development#GO:0061564;enzyme-linked receptor protein signaling pathway#GO:0007167;cell morphogenesis involved in neuron differentiation#GO:0048667;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 membrane-bound signaling molecule#PC00152;intercellular signal molecule#PC00207 CIOIN|Ensembl=ENSCING00000014484.2|UniProtKB=F6XM19 F6XM19 PTHR12081:SF7 TRANSCRIPTION FACTOR E2F TRANSCRIPTION FACTOR EFL-3 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 CIOIN|Ensembl=ENSCING00000009649.3|UniProtKB=F6XH64 F6XH64 PTHR15081:SF1 NUCLEAR AUTOANTIGENIC SPERM PROTEIN NASP -RELATED NUCLEAR AUTOANTIGENIC SPERM PROTEIN protein binding#GO:0005515;binding#GO:0005488;histone binding#GO:0042393 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;protein-DNA complex organization#GO:0071824;organelle organization#GO:0006996;chromosome organization#GO:0051276;protein-containing complex organization#GO:0043933;protein-containing complex assembly#GO:0065003;chromatin organization#GO:0006325;cellular component organization#GO:0016043;cellular process#GO:0009987;chromatin remodeling#GO:0006338;protein-DNA complex assembly#GO:0065004 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chaperone#PC00072 CIOIN|Ensembl=ENSCING00000018843.1|UniProtKB=H2XPX2 H2XPX2 LOC100184068 PTHR45945:SF3 REGULATOR OF G-PROTEIN SIGNALING LOCO REGULATOR OF G-PROTEIN SIGNALING LOCO nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;regulation of signaling#GO:0023051;biological regulation#GO:0065007;regulation of G protein-coupled receptor signaling pathway#GO:0008277 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 CIOIN|Ensembl=ENSCING00000003832.3|UniProtKB=H2XUE7 H2XUE7 PTHR14499:SF145 POTASSIUM CHANNEL TETRAMERIZATION DOMAIN-CONTAINING POTASSIUM CHANNEL REGULATORY PROTEIN-LIKE scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000021681.1|UniProtKB=H2XMP0 H2XMP0 PTHR19818:SF139 ZINC FINGER PROTEIN ZIC AND GLI PAIR-RULE PROTEIN ODD-PAIRED sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 CIOIN|Ensembl=ENSCING00000024395.1|UniProtKB=H2Y2S0 H2Y2S0 PTHR10037:SF288 VOLTAGE-GATED CATION CHANNEL CALCIUM AND SODIUM SODIUM CHANNEL PROTEIN PARA monoatomic cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;sodium channel activity#GO:0005272;monoatomic cation transmembrane transporter activity#GO:0008324;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;channel activity#GO:0015267;monoatomic ion channel activity#GO:0005216;inorganic cation transmembrane transporter activity#GO:0022890 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;membrane depolarization#GO:0051899;transport#GO:0006810;regulation of membrane potential#GO:0042391;system process#GO:0003008;action potential#GO:0001508;nervous system process#GO:0050877;cell communication#GO:0007154;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;localization#GO:0051179;sodium ion transport#GO:0006814;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;monoatomic cation transport#GO:0006812;multicellular organismal process#GO:0032501;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;sodium ion transmembrane transport#GO:0035725 membrane protein complex#GO:0098796;sodium channel complex#GO:0034706;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;cation channel complex#GO:0034703;plasma membrane#GO:0005886 transporter#PC00227;voltage-gated ion channel#PC00241 CIOIN|Ensembl=ENSCING00000012679.2|UniProtKB=A0A1W2W8J9 A0A1W2W8J9 LOC100178735 PTHR31525:SF1 HEME TRANSPORTER HRG1 HEME TRANSPORTER HRG1 tetrapyrrole binding#GO:0046906;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;binding#GO:0005488;organic cyclic compound binding#GO:0097159;heme binding#GO:0020037 localization#GO:0051179;organic substance transport#GO:0071702;metal ion transport#GO:0030001;establishment of localization#GO:0051234;transport#GO:0006810;monoatomic cation transport#GO:0006812;nitrogen compound transport#GO:0071705;iron ion transport#GO:0006826;transition metal ion transport#GO:0000041;monoatomic ion transport#GO:0006811 bounding membrane of organelle#GO:0098588;lytic vacuole membrane#GO:0098852;intracellular membrane-bounded organelle#GO:0043231;vacuolar membrane#GO:0005774;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;lytic vacuole#GO:0000323;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;lysosomal membrane#GO:0005765;lysosome#GO:0005764;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 transporter#PC00227 CIOIN|Ensembl=ENSCING00000014882.2|UniProtKB=F6YSG2 F6YSG2 PTHR16301:SF25 IMPACT-RELATED PROTEIN IMPACT cellular response to stimulus#GO:0051716;regulation of protein metabolic process#GO:0051246;regulation of amide metabolic process#GO:0034248;regulation of nitrogen compound metabolic process#GO:0051171;cellular process#GO:0009987;regulation of translational initiation#GO:0006446;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular biosynthetic process#GO:0031326;response to stress#GO:0006950;regulation of macromolecule metabolic process#GO:0060255;regulation of biosynthetic process#GO:0009889;regulation of cellular process#GO:0050794;post-transcriptional regulation of gene expression#GO:0010608;biological regulation#GO:0065007;regulation of translation#GO:0006417;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;cellular response to stress#GO:0033554;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000007476.3|UniProtKB=F6SPL5 F6SPL5 PTHR11157:SF17 FATTY ACID ACYL TRANSFERASE-RELATED ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN 6 acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824 organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;monocarboxylic acid biosynthetic process#GO:0072330;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;organic acid metabolic process#GO:0006082;membrane lipid biosynthetic process#GO:0046467;sphingolipid metabolic process#GO:0006665;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;fatty acid metabolic process#GO:0006631;membrane lipid metabolic process#GO:0006643;nitrogen compound metabolic process#GO:0006807;small molecule biosynthetic process#GO:0044283;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;sphingolipid biosynthetic process#GO:0030148;fatty acid biosynthetic process#GO:0006633;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 acyltransferase#PC00042 CIOIN|Ensembl=ENSCING00000006252.3|UniProtKB=F6V176 F6V176 PTHR43725:SF47 UDP-GLUCOSE 4-EPIMERASE UDP-GLUCOSE 4-EPIMERASE racemase and epimerase activity, acting on carbohydrates and derivatives#GO:0016857;isomerase activity#GO:0016853;catalytic activity#GO:0003824 monosaccharide metabolic process#GO:0005996;carbohydrate metabolic process#GO:0005975;organic substance metabolic process#GO:0071704;primary metabolic process#GO:0044238;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 epimerase/racemase#PC00096;metabolite interconversion enzyme#PC00262 Fructose galactose metabolism#P02744>UDP Glucose 4 epimerase#P02965 CIOIN|Ensembl=ENSCING00000000245.3|UniProtKB=F6SGU7 F6SGU7 PTHR10067:SF6 PHOSPHATIDYLSERINE DECARBOXYLASE PHOSPHATIDYLSERINE DECARBOXYLASE PROENZYME, MITOCHONDRIAL lyase activity#GO:0016829;carboxy-lyase activity#GO:0016831;carbon-carbon lyase activity#GO:0016830;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;phospholipid biosynthetic process#GO:0008654;organophosphate biosynthetic process#GO:0090407;glycerolipid biosynthetic process#GO:0045017;cellular metabolic process#GO:0044237;glycerophospholipid metabolic process#GO:0006650;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;phospholipid metabolic process#GO:0006644;lipid biosynthetic process#GO:0008610;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;primary metabolic process#GO:0044238;glycerolipid metabolic process#GO:0046486;glycerophospholipid biosynthetic process#GO:0046474;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 decarboxylase#PC00089 CIOIN|Ensembl=ENSCING00000005096.3|UniProtKB=F6WKP3 F6WKP3 LOC100186230 PTHR16083:SF85 LEUCINE RICH REPEAT CONTAINING PROTEIN FI16115P1 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000019181.1|UniProtKB=H2Y170 H2Y170 LOC100185496 PTHR11311:SF30 SPONDIN SPONDIN-LIKE TSP1 DOMAIN-CONTAINING PROTEIN cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actin filament-based process#GO:0030029;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987;organelle organization#GO:0006996 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 CIOIN|Ensembl=ENSCING00000012036.2|UniProtKB=F7AN60 F7AN60 PTHR10151:SF126 ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE ECTONUCLEOTIDE PYROPHOSPHATASE_PHOSPHODIESTERASE FAMILY MEMBER 7-LIKE metabolite interconversion enzyme#PC00262;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000001116.3|UniProtKB=F7AFG0 F7AFG0 PTHR24045:SF0 FAMILY NOT NAMED N-ACETYLGLUCOSAMINE-1-PHOSPHOTRANSFERASE SUBUNITS ALPHA_BETA CIOIN|Ensembl=ENSCING00000000551.3|UniProtKB=F6Q7P2 F6Q7P2 PTHR19288:SF93 4-NITROPHENYLPHOSPHATASE-RELATED FI11325P-RELATED hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 phosphatase#PC00181;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000022087.1|UniProtKB=H2Y3Q2 H2Y3Q2 PTHR13434:SF0 PROTEIN CASC3 PROTEIN CASC3 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000004862.3|UniProtKB=F6TBW4 F6TBW4 LOC778849 PTHR45762:SF3 ZINC FINGER RNA-BINDING PROTEIN ZINC-FINGER PROTEIN AT 72D, ISOFORM B RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000016454.2|UniProtKB=F6WCS0 F6WCS0 LOC100182593 PTHR13383:SF11 RIBONUCLEASE H2 SUBUNIT B RIBONUCLEASE H2 SUBUNIT B cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;heterocycle catabolic process#GO:0046700;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular nitrogen compound catabolic process#GO:0044270;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;organic cyclic compound catabolic process#GO:1901361;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;organic substance catabolic process#GO:1901575;nucleobase-containing compound catabolic process#GO:0034655;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248 membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 endoribonuclease#PC00094;RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000018683.1|UniProtKB=H2XND2 H2XND2 LOC100183936 PTHR46420:SF1 BETA-1,4-GLUCURONYLTRANSFERASE 1 BETA-1,4-GLUCURONYLTRANSFERASE 1 glucuronosyltransferase activity#GO:0015020;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;UDP-glycosyltransferase activity#GO:0008194 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;protein O-linked glycosylation#GO:0006493;protein O-linked mannosylation#GO:0035269;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;protein mannosylation#GO:0035268;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085;mannosylation#GO:0097502 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000016001.2|UniProtKB=F6WGT4 F6WGT4 LOC101242251 PTHR14568:SF8 TRANSMEMBRANE SUPERFAMILY 6 MEMBER 1/2 EXPERA DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000020359.1|UniProtKB=H2XYM9 H2XYM9 PTHR15129:SF0 SRC-ASSOCIATED ADAPTOR PROTEIN SH3 DOMAIN-CONTAINING PROTEIN cytoplasm#GO:0005737;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000005365.3|UniProtKB=F7BFE1 F7BFE1 PTHR24060:SF176 METABOTROPIC GLUTAMATE RECEPTOR MANGETOUT, ISOFORM G signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;adenylate cyclase inhibiting G protein-coupled glutamate receptor activity#GO:0001640;G protein-coupled receptor activity#GO:0004930;glutamate receptor activity#GO:0008066;transmembrane signaling receptor activity#GO:0004888 regulation of cell communication#GO:0010646;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of signaling#GO:0023051;cell communication#GO:0007154;cellular process#GO:0009987;glutamate receptor signaling pathway#GO:0007215;regulation of synaptic transmission, glutamatergic#GO:0051966;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;modulation of chemical synaptic transmission#GO:0050804;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 CIOIN|Ensembl=ENSCING00000002749.3|UniProtKB=F6VT59 F6VT59 LOC108949268 PTHR23049:SF71 MYOSIN REGULATORY LIGHT CHAIN 2 MYOSIN REGULATORY LIGHT CHAIN 1-RELATED cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;myosin binding#GO:0017022;binding#GO:0005488 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;myosin complex#GO:0016459;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 CIOIN|Ensembl=ENSCING00000005714.3|UniProtKB=F6WPI9 F6WPI9 PTHR21481:SF0 PROTEIN CLEC16A PROTEIN CLEC16A endosomal transport#GO:0016197;cellular localization#GO:0051641;regulation of catabolic process#GO:0009894;vacuolar transport#GO:0007034;regulation of autophagy#GO:0010506;regulation of organelle organization#GO:0033043;transport#GO:0006810;vesicle-mediated transport#GO:0016192;regulation of cellular component organization#GO:0051128;regulation of protein-containing complex disassembly#GO:0043244;regulation of macroautophagy#GO:0016241;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;localization#GO:0051179;regulation of biological process#GO:0050789;establishment of localization#GO:0051234;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;regulation of autophagosome maturation#GO:1901096;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;late endosome#GO:0005770;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000005753.3|UniProtKB=F6PZ15 F6PZ15 PTHR13490:SF0 MITOCHONDRIAL 28S RIBOSOMAL PROTEIN S28 SMALL RIBOSOMAL SUBUNIT PROTEIN MS35 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;mitochondrial ribosome#GO:0005761;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;ribosomal subunit#GO:0044391;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;organellar ribosome#GO:0000313;protein-containing complex#GO:0032991;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;small ribosomal subunit#GO:0015935;ribosome#GO:0005840;mitochondrial small ribosomal subunit#GO:0005763;mitochondrial protein-containing complex#GO:0098798 ribosomal protein#PC00202;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000003017.3|UniProtKB=F6QBK7 F6QBK7 PTHR13264:SF5 GCIP-INTERACTING PROTEIN P29 PRE-MRNA-SPLICING FACTOR SYF2 ribonucleoprotein complex#GO:1990904;catalytic step 2 spliceosome#GO:0071013;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;post-mRNA release spliceosomal complex#GO:0071014;spliceosomal complex#GO:0005681;Prp19 complex#GO:0000974;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000013721.2|UniProtKB=F6PML6 F6PML6 PTHR12992:SF11 NUDIX HYDROLASE MITOCHONDRIAL COENZYME A DIPHOSPHATASE NUDT8 hydrolase#PC00121;phosphatase#PC00181 CIOIN|Ensembl=ENSCING00000024154.1|UniProtKB=H2XM98 H2XM98 PTHR15929:SF0 STORE-OPERATED CALCIUM ENTRY-ASSOCIATED REGULATORY FACTOR STORE-OPERATED CALCIUM ENTRY-ASSOCIATED REGULATORY FACTOR CIOIN|Ensembl=ENSCING00000000019.3|UniProtKB=F6WHI9 F6WHI9 PTHR10598:SF0 SET1/ASH2 HISTONE METHYLTRANSFERASE COMPLEX SUBUNIT ASH2 SET1_ASH2 HISTONE METHYLTRANSFERASE COMPLEX SUBUNIT ASH2 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690 membrane-enclosed lumen#GO:0031974;histone methyltransferase complex#GO:0035097;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;methyltransferase complex#GO:0034708;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;Set1C/COMPASS complex#GO:0048188;nuclear protein-containing complex#GO:0140513 chromatin/chromatin-binding, or -regulatory protein#PC00077;histone modifying enzyme#PC00261 CIOIN|Ensembl=ENSCING00000000638.3|UniProtKB=F6RQQ8 F6RQQ8 PTHR17613:SF14 CEREBRAL PROTEIN-11-RELATED DEMENTIN, ISOFORM H cellular anatomical entity#GO:0110165;endomembrane system#GO:0012505 CIOIN|Ensembl=ENSCING00000004233.3|UniProtKB=F6YGG6 F6YGG6 LOC100177492 PTHR11831:SF1 30S 40S RIBOSOMAL PROTEIN U3 SMALL NUCLEOLAR RIBONUCLEOPROTEIN PROTEIN IMP3 snoRNA binding#GO:0030515;structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;structural molecule activity#GO:0005198;binding#GO:0005488;organic cyclic compound binding#GO:0097159;rRNA binding#GO:0019843 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;ribosomal small subunit biogenesis#GO:0042274;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;small-subunit processome#GO:0032040;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;ribosomal subunit#GO:0044391;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;preribosome#GO:0030684;small ribosomal subunit#GO:0015935;ribosome#GO:0005840;90S preribosome#GO:0030686;nuclear protein-containing complex#GO:0140513 ribosomal protein#PC00202 CIOIN|Ensembl=ENSCING00000020392.1|UniProtKB=H2XYY6 H2XYY6 LOC100175549 PTHR45679:SF6 ER DEGRADATION-ENHANCING ALPHA-MANNOSIDASE-LIKE PROTEIN 2 ER DEGRADATION-ENHANCING ALPHA-MANNOSIDASE-LIKE PROTEIN 2 hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 carbohydrate derivative metabolic process#GO:1901135;macromolecule modification#GO:0043412;protein catabolic process#GO:0030163;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;glycoprotein metabolic process#GO:0009100;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;macromolecule catabolic process#GO:0009057;response to endoplasmic reticulum stress#GO:0034976;response to oxygen-containing compound#GO:1901700;macromolecule metabolic process#GO:0043170;carbohydrate derivative catabolic process#GO:1901136;organonitrogen compound metabolic process#GO:1901564;ERAD pathway#GO:0036503;response to organonitrogen compound#GO:0010243;cellular process#GO:0009987;primary metabolic process#GO:0044238;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;cellular response to stress#GO:0033554 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000006997.3|UniProtKB=F6SAH8 F6SAH8 PTHR10196:SF57 SUGAR KINASE XYLULOSE KINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;carbohydrate kinase activity#GO:0019200;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301 organic hydroxy compound metabolic process#GO:1901615;monosaccharide metabolic process#GO:0005996;cellular metabolic process#GO:0044237;phosphorylation#GO:0016310;alcohol metabolic process#GO:0006066;cellular process#GO:0009987;carbohydrate metabolic process#GO:0005975;phosphorus metabolic process#GO:0006793;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 carbohydrate kinase#PC00065 Ascorbate degradation#P02729>L-xylulose kinase#P02849 CIOIN|Ensembl=ENSCING00000007442.3|UniProtKB=F6YII9 F6YII9 PTHR19134:SF531 RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE TYROSINE-PROTEIN PHOSPHATASE LAR hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;protein tyrosine phosphatase activity#GO:0004725;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 protein phosphatase#PC00195;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000007183.3|UniProtKB=F6ZAD3 F6ZAD3 PTHR10063:SF0 TUBERIN TUBERIN nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047;GTPase regulator activity#GO:0030695;molecular function activator activity#GO:0140677;GTPase activator activity#GO:0005096;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 GTPase-activating protein#PC00257 p53 pathway by glucose deprivation#P04397>TSC2#P04644;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>TSC2#P04494;p53 pathway by glucose deprivation#P04397>TSC2#G04706 CIOIN|Ensembl=ENSCING00000004295.3|UniProtKB=C4B8W9 C4B8W9 Ci-AK58 PTHR23359:SF167 NUCLEOTIDE KINASE ADENYLATE KINASE 8 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;nucleoside diphosphate kinase activity#GO:0004550;phosphotransferase activity, phosphate group as acceptor#GO:0016776;catalytic activity#GO:0003824;kinase activity#GO:0016301 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 nucleotide kinase#PC00172;kinase#PC00137 De novo purine biosynthesis#P02738>Adenylate kinase#P02896;Salvage pyrimidine ribonucleotides#P02775>Cytidylate kinase#P03153 CIOIN|Ensembl=ENSCING00000004635.3|UniProtKB=B1H3L8 B1H3L8 ache PTHR43918:SF12 ACETYLCHOLINESTERASE ACETYLCHOLINESTERASE 1 hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;nitrogen compound metabolic process#GO:0006807;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;extracellular space#GO:0005615;membrane#GO:0016020;extracellular region#GO:0005576;plasma membrane#GO:0005886 esterase#PC00097;hydrolase#PC00121 Nicotinic acetylcholine receptor signaling pathway#P00044>AChE#P01093;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>AChE#P01067;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>AChE#P01080 CIOIN|Ensembl=ENSCING00000022054.1|UniProtKB=H2XW68 H2XW68 LOC100187546 PTHR24260:SF132 FAMILY NOT NAMED PEPTIDASE S1 DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000004487.3|UniProtKB=F6TFC4 F6TFC4 PTHR45712:SF31 AGAP008170-PA PODOCAN extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 CIOIN|Ensembl=ENSCING00000000626.3|UniProtKB=F6RRL3 F6RRL3 LOC100175959 PTHR21141:SF5 60S ACIDIC RIBOSOMAL PROTEIN FAMILY MEMBER LARGE RIBOSOMAL SUBUNIT PROTEIN P2 ribosomal protein#PC00202;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000009862.3|UniProtKB=F6XFV9 F6XFV9 PTHR43788:SF16 DNA2/NAM7 HELICASE FAMILY MEMBER HELICASE WITH ZINC FINGER 2 catalytic activity, acting on a nucleic acid#GO:0140640;ATP-dependent activity, acting on DNA#GO:0008094;DNA helicase activity#GO:0003678;catalytic activity, acting on DNA#GO:0140097;helicase activity#GO:0004386;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824 DNA metabolism protein#PC00009 CIOIN|Ensembl=ENSCING00000009222.3|UniProtKB=F6W1Z3 F6W1Z3 LOC100177191 PTHR28360:SF1 DYNACTIN SUBUNIT 3 DYNACTIN SUBUNIT 3 cell cycle process#GO:0022402;cytoskeleton-dependent cytokinesis#GO:0061640;cell cycle#GO:0007049;cell division#GO:0051301;cellular process#GO:0009987;cytokinesis#GO:0000910 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 CIOIN|Ensembl=ENSCING00000018569.1|UniProtKB=H2XXZ3 H2XXZ3 PTHR45629:SF7 SNF2/RAD54 FAMILY MEMBER DNA EXCISION REPAIR PROTEIN ERCC-6-RELATED damaged DNA-binding protein#PC00086;DNA metabolism protein#PC00009 CIOIN|Ensembl=ENSCING00000013880.2|UniProtKB=F6QFQ6 F6QFQ6 PTHR32022:SF10 D-GLUTAMATE CYCLASE, MITOCHONDRIAL D-GLUTAMATE CYCLASE, MITOCHONDRIAL cyclase#PC00079;lyase#PC00144 CIOIN|Ensembl=ENSCING00000003927.3|UniProtKB=F7A4T6 F7A4T6 PTHR23355:SF9 RIBONUCLEASE DIS3-LIKE EXONUCLEASE 2 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;heterocycle catabolic process#GO:0046700;RNA metabolic process#GO:0016070;nucleobase-containing compound metabolic process#GO:0006139;cellular nitrogen compound catabolic process#GO:0044270;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;mRNA catabolic process#GO:0006402;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;organic substance catabolic process#GO:1901575;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;negative regulation of biosynthetic process#GO:0009890;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;nucleobase-containing compound catabolic process#GO:0034655;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 RNA metabolism protein#PC00031;exoribonuclease#PC00099 CIOIN|Ensembl=ENSCING00000001793.3|UniProtKB=F6X646 F6X646 LOC100176540 PTHR21844:SF2 AKT1 SUBSTRATE 1 PROTEIN PROLINE-RICH AKT1 SUBSTRATE 1 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;regulation of catalytic activity#GO:0050790;regulation of intracellular signal transduction#GO:1902531;negative regulation of TOR signaling#GO:0032007;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;negative regulation of protein phosphorylation#GO:0001933;negative regulation of protein modification process#GO:0031400;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;negative regulation of protein kinase activity#GO:0006469;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648;regulation of kinase activity#GO:0043549;regulation of protein kinase activity#GO:0045859;regulation of cell communication#GO:0010646;negative regulation of response to stimulus#GO:0048585;negative regulation of phosphorus metabolic process#GO:0010563;negative regulation of signaling#GO:0023057;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of TOR signaling#GO:0032006;regulation of response to stimulus#GO:0048583;regulation of primary metabolic process#GO:0080090;regulation of macromolecule metabolic process#GO:0060255;negative regulation of phosphorylation#GO:0042326;regulation of cellular process#GO:0050794;regulation of protein phosphorylation#GO:0001932;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of phosphate metabolic process#GO:0045936;negative regulation of signal transduction#GO:0009968;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;negative regulation of catalytic activity#GO:0043086;regulation of metabolic process#GO:0019222;negative regulation of molecular function#GO:0044092;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 CCKR signaling map#P06959>PRAS40#P07076 CIOIN|Ensembl=ENSCING00000018821.1|UniProtKB=H2XMI8 H2XMI8 PTHR47977:SF90 RAS-RELATED PROTEIN RAB RAS AND EF-HAND DOMAIN-CONTAINING PROTEIN HOMOLOG GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;ion binding#GO:0043167;anion binding#GO:0043168 localization#GO:0051179;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization#GO:0051234;transport#GO:0006810 small GTPase#PC00208;G-protein#PC00020 CIOIN|Ensembl=ENSCING00000013900.2|UniProtKB=F6PWD4 F6PWD4 PTHR16469:SF27 UBIQUITIN-ASSOCIATED AND SH3 DOMAIN-CONTAINING BA-RELATED UBIQUITIN-ASSOCIATED AND SH3 DOMAIN-CONTAINING BA-RELATED CIOIN|Ensembl=ENSCING00000024847.1|UniProtKB=H2XZX2 H2XZX2 PTHR15856:SF51 PHD FINGER PROTEIN 20-RELATED MBD-R2 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 histone acetyltransferase complex#GO:0000123;acetyltransferase complex#GO:1902493;chromatin#GO:0000785;protein-DNA complex#GO:0032993;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein acetyltransferase complex#GO:0031248;protein-containing complex#GO:0032991;chromosome#GO:0005694 CIOIN|Ensembl=ENSCING00000011430.2|UniProtKB=F7ADK7 F7ADK7 PTHR15644:SF2 OSTEOPETROSIS ASSOCIATED TRANSMEMBRANE PROTEIN 1 OSTEOPETROSIS-ASSOCIATED TRANSMEMBRANE PROTEIN 1 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000021348.1|UniProtKB=H2XWI6 H2XWI6 PTHR35169:SF3 FE2OG DIOXYGENASE DOMAIN-CONTAINING PROTEIN PROLYL 4-HYDROXYLASE ALPHA SUBUNIT FE(2+) 2OG DIOXYGENASE DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000001444.3|UniProtKB=F6W7B4 F6W7B4 LOC100175740 PTHR46013:SF7 VASCULAR CELL ADHESION MOLECULE 1 IG-LIKE DOMAIN-CONTAINING PROTEIN cell adhesion molecule#PC00069 CIOIN|Ensembl=ENSCING00000006662.3|UniProtKB=F6Q0G0 F6Q0G0 PTHR22572:SF104 SUGAR-1-PHOSPHATE GUANYL TRANSFERASE MANNOSE-1-PHOSPHATE GUANYLTRANSFERASE ALPHA transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 Mannose metabolism#P02752>Mannose 1-P guanylyl transferase#P03018 CIOIN|Ensembl=ENSCING00000012038.2|UniProtKB=F7AN54 F7AN54 LOC100175566 PTHR13143:SF6 TETRATRICOPEPTIDE REPEAT PROTEIN 19 TETRATRICOPEPTIDE REPEAT PROTEIN 19, MITOCHONDRIAL cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrial respiratory chain complex III assembly#GO:0034551;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;cytochrome complex assembly#GO:0017004;protein-containing complex assembly#GO:0065003;mitochondrion organization#GO:0007005;cellular component organization#GO:0016043;cellular process#GO:0009987 envelope#GO:0031975;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227 CIOIN|Ensembl=ENSCING00000004218.3|UniProtKB=F6YGN3 F6YGN3 LOC104265369 PTHR10383:SF9 SERINE INCORPORATOR SERINE INCORPORATOR, ISOFORM F cellular anatomical entity#GO:0110165;membrane#GO:0016020 protein-binding activity modulator#PC00095 CIOIN|Ensembl=ENSCING00000004195.3|UniProtKB=F7B568 F7B568 LOC100176028 PTHR15351:SF3 ERLIN (ER LIPID RAFT ASSOCIATED PROTEIN) HOMOLOG ERLIN small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;steroid binding#GO:0005496;sterol binding#GO:0032934;lipid binding#GO:0008289;alcohol binding#GO:0043178;cholesterol binding#GO:0015485 regulation of biological process#GO:0050789;SREBP signaling pathway#GO:0032933;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;response to stress#GO:0006950;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular response to stress#GO:0033554;cellular process#GO:0009987;signaling#GO:0023052 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000010545.3|UniProtKB=F6VP69 F6VP69 PTHR47615:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 158 COILED-COIL DOMAIN-CONTAINING PROTEIN 158 CIOIN|Ensembl=ENSCING00000004400.3|UniProtKB=F7AB73 F7AB73 PTHR13720:SF24 WD-40 REPEAT PROTEIN WD REPEAT-CONTAINING PROTEIN 90 cytoskeletal protein#PC00085;microtubule or microtubule-binding cytoskeletal protein#PC00157 CIOIN|Ensembl=ENSCING00000023521.1|UniProtKB=H2Y3A1 H2Y3A1 LOC100181776 PTHR12791:SF28 GOLGI SNARE BET1-RELATED BET1 HOMOLOG SNARE protein#PC00034 CIOIN|Ensembl=ENSCING00000004886.3|UniProtKB=F6SNM2 F6SNM2 PTHR13038:SF10 APG9 AUTOPHAGY 9 AUTOPHAGY-RELATED PROTEIN 9 cellular component assembly#GO:0022607;microautophagy#GO:0016237;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;macroautophagy#GO:0016236;macromolecule localization#GO:0033036;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;autophagy of mitochondrion#GO:0000422;cellular process#GO:0009987;organelle disassembly#GO:1903008;protein localization#GO:0008104;localization#GO:0051179;organelle assembly#GO:0070925;process utilizing autophagic mechanism#GO:0061919;cellular component organization or biogenesis#GO:0071840;reticulophagy#GO:0061709;vacuole organization#GO:0007033;cellular component disassembly#GO:0022411;cellular macromolecule localization#GO:0070727;organelle organization#GO:0006996;autophagosome assembly#GO:0000045;catabolic process#GO:0009056;mitochondrion organization#GO:0007005;autophagy#GO:0006914;piecemeal microautophagy of the nucleus#GO:0034727;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 cytoplasm#GO:0005737;phagophore assembly site#GO:0000407;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;autophagosome#GO:0005776;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000003315.2|UniProtKB=F6TBB0 F6TBB0 PTHR12705:SF0 ORIGIN RECOGNITION COMPLEX SUBUNIT 5 ORIGIN RECOGNITION COMPLEX SUBUNIT 5 sequence-specific double-stranded DNA binding#GO:1990837;DNA replication origin binding#GO:0003688;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;DNA-templated DNA replication#GO:0006261;DNA replication#GO:0006260;DNA replication initiation#GO:0006270;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 origin recognition complex#GO:0000808;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;nuclear origin of replication recognition complex#GO:0005664;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 DNA metabolism protein#PC00009;replication origin binding protein#PC00199 CIOIN|Ensembl=ENSCING00000008790.3|UniProtKB=F6SDB4 F6SDB4 foxm PTHR46878:SF1 FORKHEAD BOX PROTEIN M1 FORKHEAD BOX PROTEIN M1 helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 CIOIN|Ensembl=ENSCING00000007685.3|UniProtKB=F6SIL2 F6SIL2 LOC100176265 PTHR24247:SF265 5-HYDROXYTRYPTAMINE RECEPTOR MUSCARINIC ACETYLCHOLINE RECEPTOR DM1 signaling receptor activity#GO:0038023;G protein-coupled amine receptor activity#GO:0008227;molecular transducer activity#GO:0060089;neurotransmitter receptor activity#GO:0030594;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 response to organic substance#GO:0010033;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to nitrogen compound#GO:1901699;response to nitrogen compound#GO:1901698;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to oxygen-containing compound#GO:1901701;chemical synaptic transmission#GO:0007268;response to chemical#GO:0042221;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;synaptic signaling#GO:0099536;G protein-coupled receptor signaling pathway#GO:0007186;cell-cell signaling#GO:0007267;signaling#GO:0023052;acetylcholine receptor signaling pathway#GO:0095500 synapse#GO:0045202;somatodendritic compartment#GO:0036477;neuron projection#GO:0043005;cell junction#GO:0030054;dendrite#GO:0030425;cell projection#GO:0042995;cell periphery#GO:0071944;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GqPCR#P00730 CIOIN|Ensembl=ENSCING00000019585.1|UniProtKB=H2Y1A3 H2Y1A3 LOC100185013 PTHR13247:SF0 TETRATRICOPEPTIDE REPEAT PROTEIN 11 TPR REPEAT PROTEIN 11 MITOCHONDRIAL FISSION 1 PROTEIN cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;autophagy of mitochondrion#GO:0000422;cellular process#GO:0009987;organelle disassembly#GO:1903008;process utilizing autophagic mechanism#GO:0061919;cellular component organization or biogenesis#GO:0071840;cellular component disassembly#GO:0022411;organelle organization#GO:0006996;organelle fission#GO:0048285;catabolic process#GO:0009056;mitochondrion organization#GO:0007005;peroxisome organization#GO:0007031;autophagy#GO:0006914;mitochondrial fission#GO:0000266;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 envelope#GO:0031975;bounding membrane of organelle#GO:0098588;peroxisomal membrane#GO:0005778;mitochondrial membrane#GO:0031966;intracellular membrane-bounded organelle#GO:0043231;mitochondrial outer membrane#GO:0005741;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;mitochondrial envelope#GO:0005740;microbody#GO:0042579;membrane-bounded organelle#GO:0043227;peroxisome#GO:0005777;outer membrane#GO:0019867 CIOIN|Ensembl=ENSCING00000005948.3|UniProtKB=Q1RPW1 Q1RPW1 Ci-ZF(DHHC)-1 PTHR22883:SF147 ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN PALMITOYLTRANSFERASE palmitoyltransferase activity#GO:0016409;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular localization#GO:0051641;macromolecule localization#GO:0033036;macromolecule modification#GO:0043412;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;biosynthetic process#GO:0009058;establishment of protein localization#GO:0045184;establishment of protein localization to membrane#GO:0090150;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;protein palmitoylation#GO:0018345;protein metabolic process#GO:0019538;protein lipidation#GO:0006497;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;localization within membrane#GO:0051668;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein localization to membrane#GO:0072657;organonitrogen compound biosynthetic process#GO:1901566;protein targeting#GO:0006605;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;protein acylation#GO:0043543;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;lipoprotein biosynthetic process#GO:0042158;protein localization#GO:0008104;primary metabolic process#GO:0044238;localization#GO:0051179;protein targeting to membrane#GO:0006612;cellular macromolecule localization#GO:0070727;lipoprotein metabolic process#GO:0042157 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000022096.1|UniProtKB=H2Y013 H2Y013 LOC100182124 PTHR12789:SF0 DENSITY-REGULATED PROTEIN HOMOLOG DENSITY-REGULATED PROTEIN nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular component biogenesis#GO:0044085;peptide metabolic process#GO:0006518;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;translation#GO:0006412;protein-RNA complex assembly#GO:0022618;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular component assembly#GO:0022607;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cytoplasmic translation#GO:0002181;cellular component organization#GO:0016043;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;cytoplasmic translational initiation#GO:0002183;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;cellular component organization or biogenesis#GO:0071840;peptide biosynthetic process#GO:0043043;protein-containing complex organization#GO:0043933;ribonucleoprotein complex biogenesis#GO:0022613;translational initiation#GO:0006413;protein-RNA complex organization#GO:0071826 translation initiation factor#PC00224;translation factor#PC00223;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000018693.1|UniProtKB=H2XZ95 H2XZ95 s-themis-a PTHR10877:SF183 POLYCYSTIN FAMILY MEMBER AT14535P-RELATED ion channel#PC00133;transporter#PC00227 CIOIN|Ensembl=ENSCING00000024385.1|UniProtKB=H2Y130 H2Y130 PTHR11679:SF3 VESICLE PROTEIN SORTING-ASSOCIATED VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 45 cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907 cytoplasm#GO:0005737;bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;Golgi membrane#GO:0000139;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 membrane trafficking regulatory protein#PC00151 CIOIN|Ensembl=ENSCING00000005543.3|UniProtKB=F6XEU0 F6XEU0 LOC100183161 PTHR31547:SF1 MULTIVESICULAR BODY SUBUNIT 12B MULTIVESICULAR BODY SUBUNIT 12B regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;regulation of epidermal growth factor receptor signaling pathway#GO:0042058;regulation of signaling#GO:0023051;biological regulation#GO:0065007;regulation of ERBB signaling pathway#GO:1901184 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;vesicle membrane#GO:0012506;organelle#GO:0043226;membrane#GO:0016020;endosome membrane#GO:0010008;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;ESCRT I complex#GO:0000813;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cytoplasmic vesicle membrane#GO:0030659;late endosome#GO:0005770 CIOIN|Ensembl=ENSCING00000007463.3|UniProtKB=F6YIR9 F6YIR9 PTHR13129:SF4 VPRBP PROTEIN-RELATED DDB1- AND CUL4-ASSOCIATED FACTOR 1 protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cullin-RING ubiquitin ligase complex#GO:0031461;catalytic complex#GO:1902494;transferase complex#GO:1990234;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;Cul4-RING E3 ubiquitin ligase complex#GO:0080008 CIOIN|Ensembl=ENSCING00000005809.3|UniProtKB=F6V7V9 F6V7V9 PTHR10257:SF3 SERINE/THREONINE PROTEIN PHOSPHATASE 2A PP2A REGULATORY SUBUNIT B SERINE_THREONINE-PROTEIN PHOSPHATASE 2A 56 KDA REGULATORY SUBUNIT GAMMA ISOFORM protein phosphatase#PC00195;protein modifying enzyme#PC00260 Wnt signaling pathway#P00057>PP2A#P01438;FGF signaling pathway#P00021>PP2A#P00629;EGF receptor signaling pathway#P00018>PP2A#P00547 CIOIN|Ensembl=ENSCING00000005608.3|UniProtKB=F7ATT1 F7ATT1 LOC100181635 PTHR11669:SF20 REPLICATION FACTOR C / DNA POLYMERASE III GAMMA-TAU SUBUNIT REPLICATION FACTOR C SUBUNIT 4 ATP-dependent activity, acting on DNA#GO:0008094;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on DNA#GO:0140097;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;response to stress#GO:0006950;nitrogen compound metabolic process#GO:0006807;DNA-templated DNA replication#GO:0006261;DNA replication#GO:0006260;cellular response to stress#GO:0033554;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;replication fork#GO:0005657 DNA-directed DNA polymerase#PC00018 DNA replication#P00017>RFC#P00529 CIOIN|Ensembl=ENSCING00000012974.2|UniProtKB=Q1RL34 Q1RL34 Ci-Sir2-e PTHR11085:SF6 NAD-DEPENDENT PROTEIN DEACYLASE SIRTUIN-5, MITOCHONDRIAL-RELATED NAD-DEPENDENT PROTEIN DEACETYLASE SIRTUIN-2 nucleotide binding#GO:0000166;histone modifying activity#GO:0140993;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;deacetylase activity#GO:0019213;histone deacetylase activity#GO:0004407;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;anion binding#GO:0043168;catalytic activity, acting on a protein#GO:0140096 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000006227.3|UniProtKB=F6YVE9 F6YVE9 LOC100183552 PTHR24126:SF67 ANKYRIN REPEAT, PH AND SEC7 DOMAIN CONTAINING PROTEIN SECG-RELATED 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 10 RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;protein binding#GO:0005515;transcription factor binding#GO:0008134;binding#GO:0005488;DNA-binding transcription factor binding#GO:0140297 regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000024217.1|UniProtKB=H2Y061 H2Y061 PTHR42758:SF2 PHOSPHATIDYLGLYCEROL PHOSPHOLIPASE C PHOSPHATIDYLGLYCEROL PHOSPHOLIPASE C hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphoric diester hydrolase activity#GO:0008081;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 lipid metabolic process#GO:0006629;cellular metabolic process#GO:0044237;glycerophospholipid metabolic process#GO:0006650;glycerolipid catabolic process#GO:0046503;glycerophospholipid catabolic process#GO:0046475;lipid catabolic process#GO:0016042;cellular process#GO:0009987;phospholipid metabolic process#GO:0006644;phosphorus metabolic process#GO:0006793;organophosphate catabolic process#GO:0046434;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;phospholipid catabolic process#GO:0009395;catabolic process#GO:0009056;organophosphate metabolic process#GO:0019637;organic substance catabolic process#GO:1901575;cellular lipid metabolic process#GO:0044255;cellular lipid catabolic process#GO:0044242;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 phospholipase#PC00186 CIOIN|Ensembl=ENSCING00000006749.3|UniProtKB=F6Y050 F6Y050 PTHR45632:SF27 LD33804P KELCH-LIKE PROTEIN 9 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000005697.3|UniProtKB=F6WQJ1 F6WQJ1 LOC100183726 PTHR44313:SF1 DNAJ HOMOLOG SUBFAMILY C MEMBER 17 DNAJ HOMOLOG SUBFAMILY C MEMBER 17 cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;RNA processing#GO:0006396;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;mRNA metabolic process#GO:0016071;cellular component disassembly#GO:0022411;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;protein-containing complex disassembly#GO:0032984;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;protein-containing complex organization#GO:0043933;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;protein-RNA complex organization#GO:0071826;RNA splicing, via transesterification reactions#GO:0000375 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chaperone#PC00072 CIOIN|Ensembl=ENSCING00000020643.1|UniProtKB=H2XRF5 H2XRF5 PTHR23050:SF518 CALCIUM BINDING PROTEIN AT16150P-RELATED cation binding#GO:0043169;small molecule binding#GO:0036094;molecular function regulator activity#GO:0098772;binding#GO:0005488;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;enzyme regulator activity#GO:0030234 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 calmodulin-related#PC00061 B cell activation#P00010>Calmodulin#P00375;Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Calmodulin#P00755;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Phosphorylase b kinase#P00716;T cell activation#P00053>Calmodulin#P01305 CIOIN|Ensembl=ENSCING00000024819.1|UniProtKB=H2XM20 H2XM20 LOC100178761 PTHR15627:SF14 NATURAL KILLER CELL-SPECIFIC ANTIGEN KLIP1 PROTEIN YIPF3 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000012466.2|UniProtKB=F6UTV8 F6UTV8 PTHR43050:SF1 SERINE / THREONINE RACEMASE FAMILY MEMBER SERINE RACEMASE carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;magnesium ion binding#GO:0000287;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;metal ion binding#GO:0046872;isomerase activity#GO:0016853;cation binding#GO:0043169;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;lyase activity#GO:0016829;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167;ATP binding#GO:0005524 organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;alpha-amino acid biosynthetic process#GO:1901607;nitrogen compound metabolic process#GO:0006807;amino acid biosynthetic process#GO:0008652;alpha-amino acid metabolic process#GO:1901605;small molecule biosynthetic process#GO:0044283;carboxylic acid metabolic process#GO:0019752;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 epimerase/racemase#PC00096 Isoleucine biosynthesis#P02748>Threonine dehydratase#P02995 CIOIN|Ensembl=ENSCING00000006708.3|UniProtKB=F7AR57 F7AR57 LOC100181555 PTHR11161:SF0 O-ACYLTRANSFERASE O-ACYLTRANSFERASE LIKE PROTEIN acyltransferase#PC00042 CIOIN|Ensembl=ENSCING00000020987.1|UniProtKB=H2XMK3 H2XMK3 LOC100182624 PTHR22802:SF379 C-TYPE LECTIN SUPERFAMILY MEMBER CHONDROITIN SULFATE PROTEOGLYCAN 2 ISOFORM X1 membrane traffic protein#PC00150 CIOIN|Ensembl=ENSCING00000020424.1|UniProtKB=H2XXI4 H2XXI4 PTHR11461:SF211 SERINE PROTEASE INHIBITOR, SERPIN GH10112P-RELATED protease inhibitor#PC00191 CIOIN|Ensembl=ENSCING00000013167.2|UniProtKB=F6WTS0 F6WTS0 LOC100176687 PTHR23503:SF8 SOLUTE CARRIER FAMILY 2 FACILITATED GLUCOSE TRANSPORTER PROTEIN 1 transmembrane transporter activity#GO:0022857;sugar transmembrane transporter activity#GO:0051119;transporter activity#GO:0005215;carbohydrate transmembrane transporter activity#GO:0015144 localization#GO:0051179;organic substance transport#GO:0071702;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810;cellular process#GO:0009987;carbohydrate transmembrane transport#GO:0034219;carbohydrate transport#GO:0008643 cellular anatomical entity#GO:0110165;membrane#GO:0016020 secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000002322.3|UniProtKB=F6PP06 F6PP06 PTHR33504:SF2 NADH DEHYDROGENASE (UBIQUINONE) 1 BETA SUBCOMPLEX, 4 PROTEIN MFI dehydrogenase#PC00092;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000002746.3|UniProtKB=F7AHV7 F7AHV7 LOC100185648 PTHR11941:SF171 ENOYL-COA HYDRATASE-RELATED SD19268P oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;lipid oxidation#GO:0034440;cellular metabolic process#GO:0044237;lipid catabolic process#GO:0016042;lipid modification#GO:0030258;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;fatty acid catabolic process#GO:0009062;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;fatty acid metabolic process#GO:0006631;small molecule catabolic process#GO:0044282;fatty acid beta-oxidation#GO:0006635;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;cellular lipid metabolic process#GO:0044255;cellular lipid catabolic process#GO:0044242;carboxylic acid metabolic process#GO:0019752;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;monocarboxylic acid catabolic process#GO:0072329 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 hydratase#PC00120 CIOIN|Ensembl=ENSCING00000004938.3|UniProtKB=F6X9M4 F6X9M4 PTHR11616:SF182 SODIUM/CHLORIDE DEPENDENT TRANSPORTER TRANSPORTER metal ion transport#GO:0030001;transmembrane transport#GO:0055085;amino acid transport#GO:0006865;organic anion transport#GO:0015711;organic acid transport#GO:0015849;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;localization#GO:0051179;organic substance transport#GO:0071702;sodium ion transport#GO:0006814;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;sodium ion transmembrane transport#GO:0035725 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 primary active transporter#PC00068;transporter#PC00227 Adrenaline and noradrenaline biosynthesis#P00001>amine translocator#P00068 CIOIN|Ensembl=ENSCING00000007210.3|UniProtKB=F6Y7F7 F6Y7F7 PTHR12822:SF2 PROTEIN YIPF PROTEIN YIPF cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000008913.3|UniProtKB=F6QB29 F6QB29 PTHR11588:SF501 TUBULIN TUBULIN ALPHA CHAIN carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;structural molecule activity#GO:0005198;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167;structural constituent of cytoskeleton#GO:0005200 cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;microtubule-based process#GO:0007017;organelle organization#GO:0006996;microtubule cytoskeleton organization#GO:0000226;cytoskeleton organization#GO:0007010;cell cycle#GO:0007049;cellular component organization#GO:0016043;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622 tubulin#PC00228;microtubule or microtubule-binding cytoskeletal protein#PC00157 CIOIN|Ensembl=ENSCING00000007005.3|UniProtKB=F6SAD5 F6SAD5 PTHR10026:SF51 CYCLIN CYCLIN-T protein kinase activator activity#GO:0030295;protein kinase regulator activity#GO:0019887;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;protein serine/threonine kinase activator activity#GO:0043539;enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;kinase regulator activity#GO:0019207;kinase activator activity#GO:0019209 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of DNA-templated transcription, elongation#GO:0032786;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;regulation of DNA-templated transcription elongation#GO:0032784;regulation of DNA-templated transcription#GO:0006355;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA metabolic process#GO:0051252;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;positive regulation of RNA metabolic process#GO:0051254;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;serine/threonine protein kinase complex#GO:1902554;protein kinase complex#GO:1902911;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;transcription elongation factor complex#GO:0008023;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 kinase activator#PC00138 CIOIN|Ensembl=ENSCING00000005102.3|UniProtKB=F6WKD5 F6WKD5 zf(an1_a20like)-2 PTHR43788:SF8 DNA2/NAM7 HELICASE FAMILY MEMBER DNA-BINDING PROTEIN SMUBP-2 catalytic activity, acting on a nucleic acid#GO:0140640;ATP-dependent activity, acting on DNA#GO:0008094;DNA helicase activity#GO:0003678;catalytic activity, acting on DNA#GO:0140097;helicase activity#GO:0004386;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824 DNA metabolism protein#PC00009 CIOIN|Ensembl=ENSCING00000008153.3|UniProtKB=F6VFA8 F6VFA8 LOC100178657 PTHR47456:SF1 PHD-TYPE DOMAIN-CONTAINING PROTEIN PHD-TYPE DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000018274.1|UniProtKB=H2XTT8 H2XTT8 PTHR12735:SF27 BOLA-LIKE PROTEIN-RELATED BOLA-LIKE PROTEIN 2 small molecule binding#GO:0036094;binding#GO:0005488;iron-sulfur cluster binding#GO:0051536 inorganic ion homeostasis#GO:0098771;intracellular iron ion homeostasis#GO:0006879;intracellular monoatomic cation homeostasis#GO:0030003;homeostatic process#GO:0042592;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic ion homeostasis#GO:0006873;chemical homeostasis#GO:0048878;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;monoatomic ion homeostasis#GO:0050801 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000020188.1|UniProtKB=H2Y3J8 H2Y3J8 PTHR23344:SF50 GLYCEROPHOSPHORYL DIESTER PHOSPHODIESTERASE GP-PDE DOMAIN-CONTAINING PROTEIN phosphodiesterase#PC00185;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000003621.3|UniProtKB=F6U8Y1 F6U8Y1 PTHR24372:SF77 GLYCOPROTEIN HORMONE RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 response to organic substance#GO:0010033;positive regulation of adenylate cyclase activity#GO:0045762;regulation of lyase activity#GO:0051339;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;cellular response to stimulus#GO:0051716;regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;cellular response to endogenous stimulus#GO:0071495;cellular response to chemical stimulus#GO:0070887;positive regulation of catalytic activity#GO:0043085;cellular response to organic substance#GO:0071310;regulation of cyclase activity#GO:0031279;positive regulation of molecular function#GO:0044093;cell communication#GO:0007154;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;positive regulation of cyclase activity#GO:0031281;hormone-mediated signaling pathway#GO:0009755;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to endogenous stimulus#GO:0009719;response to hormone#GO:0009725;cellular response to hormone stimulus#GO:0032870;response to chemical#GO:0042221;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of lyase activity#GO:0051349;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 CIOIN|Ensembl=ENSCING00000014384.2|UniProtKB=F7AFM4 F7AFM4 PTHR12137:SF54 CARBOHYDRATE SULFOTRANSFERASE CARBOHYDRATE SULFOTRANSFERASE sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824 transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000007105.3|UniProtKB=F6VLQ0 F6VLQ0 PTHR24110:SF3 CENTROSOMAL PROTEIN OF 78 KDA CENTROSOMAL PROTEIN OF 78 KDA CIOIN|Ensembl=ENSCING00000024547.1|UniProtKB=H2XXS5 H2XXS5 PTHR12972:SF0 DOWNSTREAM NEIGHBOR OF SON PROTEIN DOWNSTREAM NEIGHBOR OF SON cellular aromatic compound metabolic process#GO:0006725;nuclear DNA replication#GO:0033260;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;cell cycle process#GO:0022402;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;DNA-templated DNA replication#GO:0006261;cell cycle#GO:0007049;DNA replication#GO:0006260;DNA metabolic process#GO:0006259;cell cycle DNA replication#GO:0044786;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000005174.3|UniProtKB=F6RY16 F6RY16 LOC100178307 PTHR11863:SF226 STEROL DESATURASE FATTY ACID HYDROXYLASE DOMAIN-CONTAINING PROTEIN 2-RELATED oxidase#PC00175;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000007185.3|UniProtKB=F6ZAA5 F6ZAA5 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE SSU-1 sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824 cellular metabolic process#GO:0044237;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000023326.1|UniProtKB=H2XWW7 H2XWW7 PTHR11216:SF31 EH DOMAIN AT21416P localization#GO:0051179;endosomal transport#GO:0016197;cellular localization#GO:0051641;establishment of localization#GO:0051234;transport#GO:0006810;endocytosis#GO:0006897;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;cellular process#GO:0009987;import into cell#GO:0098657 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 membrane traffic protein#PC00150 CIOIN|Ensembl=ENSCING00000006438.3|UniProtKB=F6PQ94 F6PQ94 LOC100184123 PTHR32465:SF0 BARDET-BIEDL SYNDROME 2 PROTEIN BARDET-BIEDL SYNDROME 2 PROTEIN organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cell projection organization#GO:0030030;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031 microtubule organizing center#GO:0005815;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;motile cilium#GO:0031514;microtubule cytoskeleton#GO:0015630;ciliary basal body#GO:0036064;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cytoskeleton#GO:0005856;BBSome#GO:0034464;cilium#GO:0005929 CIOIN|Ensembl=ENSCING00000003934.3|UniProtKB=F7A4U7 F7A4U7 LOC100185667 PTHR11506:SF41 LYSOSOME-ASSOCIATED MEMBRANE GLYCOPROTEIN LYSOSOME-ASSOCIATED MEMBRANE GLYCOPROTEIN 1-LIKE localization#GO:0051179;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;protein localization to organelle#GO:0033365;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104 bounding membrane of organelle#GO:0098588;lytic vacuole membrane#GO:0098852;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuolar membrane#GO:0005774;late endosome membrane#GO:0031902;vacuole#GO:0005773;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endosome membrane#GO:0010008;lytic vacuole#GO:0000323;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;lysosomal membrane#GO:0005765;lysosome#GO:0005764;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle membrane#GO:0030659;late endosome#GO:0005770;plasma membrane#GO:0005886 membrane trafficking regulatory protein#PC00151 CIOIN|Ensembl=ENSCING00000006983.3|UniProtKB=F6SY86 F6SY86 LOC100180749 PTHR19302:SF27 GAMMA TUBULIN COMPLEX PROTEIN GAMMA-TUBULIN COMPLEX COMPONENT 4 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;meiotic cell cycle#GO:0051321;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;cellular process#GO:0009987;microtubule polymerization or depolymerization#GO:0031109;chromosome segregation#GO:0007059;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;reproduction#GO:0000003;microtubule polymerization#GO:0046785;microtubule-based process#GO:0007017;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;supramolecular fiber organization#GO:0097435;sexual reproduction#GO:0019953;protein polymerization#GO:0051258;spindle assembly#GO:0051225;reproductive process#GO:0022414;cell cycle#GO:0007049;cytoskeleton organization#GO:0007010;spindle organization#GO:0007051;non-membrane-bounded organelle assembly#GO:0140694;microtubule nucleation#GO:0007020;cytoplasmic microtubule organization#GO:0031122 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 CIOIN|Ensembl=ENSCING00000020543.1|UniProtKB=H2XZT7 H2XZT7 PTHR10283:SF82 SOLUTE CARRIER FAMILY 13 MEMBER SOLUTE CARRIER FAMILY 13 MEMBER 2 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 localization#GO:0051179;establishment of localization#GO:0051234;cellular process#GO:0009987;transmembrane transport#GO:0055085;transport#GO:0006810 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000003910.3|UniProtKB=F6SML9 F6SML9 LOC100183358 PTHR44133:SF2 CLEAVAGE STIMULATION FACTOR SUBUNIT 1 CLEAVAGE STIMULATION FACTOR SUBUNIT 1 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;mRNA cleavage factor complex#GO:0005849;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000014316.2|UniProtKB=F6UMR8 F6UMR8 PTHR22884:SF413 SET DOMAIN PROTEINS NUCLEAR RECEPTOR BINDING SET DOMAIN PROTEIN-RELATED N-methyltransferase activity#GO:0008170;histone modifying activity#GO:0140993;transferase activity#GO:0016740;catalytic activity#GO:0003824;histone methyltransferase activity#GO:0042054;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;protein-lysine N-methyltransferase activity#GO:0016279;catalytic activity, acting on a protein#GO:0140096;lysine N-methyltransferase activity#GO:0016278;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;protein methyltransferase activity#GO:0008276 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000005986.3|UniProtKB=F6V5B4 F6V5B4 PTHR11616:SF286 SODIUM/CHLORIDE DEPENDENT TRANSPORTER SODIUM- AND CHLORIDE-DEPENDENT NEUTRAL AND BASIC AMINO ACID TRANSPORTER B(0+) inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;organic acid:sodium symporter activity#GO:0005343;organic acid transmembrane transporter activity#GO:0005342;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;organic anion transmembrane transporter activity#GO:0008514;monoatomic cation transmembrane transporter activity#GO:0008324;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;amino acid:sodium symporter activity#GO:0005283;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;branched-chain amino acid transmembrane transporter activity#GO:0015658;organic cation transmembrane transporter activity#GO:0015101;metal ion transmembrane transporter activity#GO:0046873;active monoatomic ion transmembrane transporter activity#GO:0022853;amino acid transmembrane transporter activity#GO:0015171;inorganic cation transmembrane transporter activity#GO:0022890;neutral L-amino acid transmembrane transporter activity#GO:0015175;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294 neutral amino acid transport#GO:0015804;quaternary ammonium group transport#GO:0015697;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;organic anion transport#GO:0015711;amino acid transport#GO:0006865;organic acid transport#GO:0015849;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;amino acid import across plasma membrane#GO:0089718;carboxylic acid transmembrane transport#GO:1905039;localization#GO:0051179;organic substance transport#GO:0071702;import across plasma membrane#GO:0098739;amino acid transmembrane transport#GO:0003333;sodium ion transport#GO:0006814;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;organic cation transport#GO:0015695;monoatomic cation transport#GO:0006812;organic acid transmembrane transport#GO:1903825;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655;import into cell#GO:0098657;sodium ion transmembrane transport#GO:0035725 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 primary active transporter#PC00068;transporter#PC00227 CIOIN|Ensembl=ENSCING00000007650.3|UniProtKB=F6VWX8 F6VWX8 LOC619278 PTHR10199:SF118 THROMBOSPONDIN THROMBOSPONDIN external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165 cell adhesion molecule#PC00069 CIOIN|Ensembl=ENSCING00000020273.1|UniProtKB=H2XPM7 H2XPM7 PTHR11886:SF35 DYNEIN LIGHT CHAIN DYNEIN LIGHT CHAIN protein binding#GO:0005515;binding#GO:0005488 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;microtubule cytoskeleton#GO:0015630;dynein complex#GO:0030286;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic dynein complex#GO:0005868;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;microtubule or microtubule-binding cytoskeletal protein#PC00157 Huntington disease#P00029>Dynein complex#P00774 CIOIN|Ensembl=ENSCING00000008587.3|UniProtKB=F6UDE2 F6UDE2 PTHR11929:SF145 ALPHA- 1,3 -FUCOSYLTRANSFERASE ALPHA-(1,3)-FUCOSYLTRANSFERASE FUT-1 transferase activity#GO:0016740;fucosyltransferase activity#GO:0008417;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 glycosylation#GO:0070085;metabolic process#GO:0008152 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000023236.1|UniProtKB=H2XRT6 H2XRT6 PTHR12857:SF0 CXXC MOTIF CONTAINING ZINC BINDING PROTEIN CXXC MOTIF CONTAINING ZINC BINDING PROTEIN cation binding#GO:0043169;metal ion binding#GO:0046872;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;zinc ion binding#GO:0008270;transition metal ion binding#GO:0046914 CIOIN|Ensembl=ENSCING00000007025.3|UniProtKB=F7AE45 F7AE45 PTHR46573:SF1 WD REPEAT, SAM AND U-BOX DOMAIN-CONTAINING PROTEIN 1 WD REPEAT, SAM AND U-BOX DOMAIN-CONTAINING PROTEIN 1 CIOIN|Ensembl=ENSCING00000002594.3|UniProtKB=F6Q318 F6Q318 PTHR12623:SF10 NGFI-A BINDING PROTEIN NGFI-A-BINDING PROTEIN HOMOLOG molecular adaptor activity#GO:0060090;transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;protein binding#GO:0005515;transcription factor binding#GO:0008134;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674 regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000001530.3|UniProtKB=F6Z3V6 F6Z3V6 PTHR32170:SF3 PROTEASOME ACTIVATOR COMPLEX SUBUNIT 4 PROTEASOME ACTIVATOR COMPLEX SUBUNIT 4 peptidase activator activity#GO:0016504;proteasome binding#GO:0070628;molecular function activator activity#GO:0140677;binding#GO:0005488;molecular function regulator activity#GO:0098772;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;peptidase regulator activity#GO:0061134;enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;histone binding#GO:0042393;modification-dependent protein binding#GO:0140030 macromolecule catabolic process#GO:0009057;nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;proteolysis#GO:0006508;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;catabolic process#GO:0009056;organonitrogen compound catabolic process#GO:1901565;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000008082.3|UniProtKB=F6Z6N2 F6Z6N2 PTHR13681:SF26 SURVIVAL OF MOTOR NEURON-RELATED-SPLICING FACTOR 30-RELATED SURVIVAL OF MOTOR NEURON-RELATED-SPLICING FACTOR 30 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA splicing factor#PC00148;RNA processing factor#PC00147 CIOIN|Ensembl=ENSCING00000021165.1|UniProtKB=H2XR59 H2XR59 PTHR46467:SF1 TETHER CONTAINING UBX DOMAIN FOR GLUT4 TETHER CONTAINING UBX DOMAIN FOR GLUT4 localization#GO:0051179;organic substance transport#GO:0071702;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;transport#GO:0006810;protein transport#GO:0015031;nitrogen compound transport#GO:0071705;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000004633.3|UniProtKB=F6PTH0 F6PTH0 PTHR43115:SF4 DEHYDROGENASE/REDUCTASE SDR FAMILY MEMBER 11 DEHYDROGENASE_REDUCTASE SDR FAMILY MEMBER 11 oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000019761.1|UniProtKB=H2XU43 H2XU43 PTHR24229:SF109 NEUROPEPTIDES RECEPTOR SOMATOSTATIN RECEPTOR TYPE 2-LIKE neuropeptide binding#GO:0042923;signaling receptor activity#GO:0038023;binding#GO:0005488;peptide binding#GO:0042277;amide binding#GO:0033218;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;neuropeptide signaling pathway#GO:0007218;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;neuron projection#GO:0043005;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 CIOIN|Ensembl=ENSCING00000023087.1|UniProtKB=H2Y1I1 H2Y1I1 PTHR23220:SF133 INTEGRIN ALPHA INTEGRIN ALPHA-PS2 cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;integrin binding#GO:0005178;binding#GO:0005488;signaling receptor binding#GO:0005102 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cell adhesion mediated by integrin#GO:0033627;cell-cell adhesion#GO:0098609;cell communication#GO:0007154;cell adhesion#GO:0007155;cell-substrate adhesion#GO:0031589;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cell-matrix adhesion#GO:0007160;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;integrin-mediated signaling pathway#GO:0007229;biological regulation#GO:0065007;signaling#GO:0023052 receptor complex#GO:0043235;membrane protein complex#GO:0098796;external side of plasma membrane#GO:0009897;cell surface#GO:0009986;protein-containing complex#GO:0032991;plasma membrane signaling receptor complex#GO:0098802;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 cell adhesion molecule#PC00069;integrin#PC00126 Integrin signalling pathway#P00034>Integrin alpha#P00941 CIOIN|Ensembl=ENSCING00000002194.3|UniProtKB=F6S569 F6S569 LOC100179217 PTHR24070:SF226 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY GTP-BINDING PROTEIN RHEB HOMOLOG GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;anion binding#GO:0043168;ion binding#GO:0043167 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;small GTPase-mediated signal transduction#GO:0007264;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signaling cassette#GO:0141124;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 small GTPase#PC00208;G-protein#PC00020 p53 pathway by glucose deprivation#P04397>Rheb#P04642;TGF-beta signaling pathway#P00052>Ras-GDP#P01291;TGF-beta signaling pathway#P00052>Ras-GTP#P01280 CIOIN|Ensembl=ENSCING00000013434.2|UniProtKB=F6V318 F6V318 LOC100180222 PTHR22957:SF657 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN PH DOMAIN-CONTAINING PROTEIN nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 regulation of molecular function#GO:0065009;regulation of GTPase activity#GO:0043087;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;activation of GTPase activity#GO:0090630;biological regulation#GO:0065007;positive regulation of molecular function#GO:0044093;regulation of hydrolase activity#GO:0051336;regulation of catalytic activity#GO:0050790;positive regulation of hydrolase activity#GO:0051345 GTPase-activating protein#PC00257 CIOIN|Ensembl=ENSCING00000016538.2|UniProtKB=F6Y2C5 F6Y2C5 PTHR10157:SF23 DOPAMINE BETA HYDROXYLASE RELATED MOXD1 HOMOLOG 1 hydroxylase#PC00122 CIOIN|Ensembl=ENSCING00000023946.1|UniProtKB=H2XZE6 H2XZE6 PTHR13483:SF11 BOX C_D SNORNA PROTEIN 1-RELATED ZINC FINGER HIT DOMAIN-CONTAINING PROTEIN 3 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;macromolecule localization#GO:0033036;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;RNA processing#GO:0006396;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;biosynthetic process#GO:0009058;ribosomal large subunit biogenesis#GO:0042273;nucleobase-containing compound metabolic process#GO:0006139;RNA localization#GO:0006403;protein-RNA complex assembly#GO:0022618;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;ribosome biogenesis#GO:0042254;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;protein-containing complex organization#GO:0043933;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;protein-RNA complex organization#GO:0071826;maturation of LSU-rRNA#GO:0000470 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000022362.1|UniProtKB=H2XV68 H2XV68 LOC100183409 PTHR21575:SF12 PROTEIN HID1 PROTEIN HID1 cytoplasm#GO:0005737;Golgi cisterna#GO:0031985;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;Golgi apparatus subcompartment#GO:0098791;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;Golgi stack#GO:0005795;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000010672.3|UniProtKB=F6SD48 F6SD48 PTHR42985:SF45 SODIUM-COUPLED MONOCARBOXYLATE TRANSPORTER SODIUM_IODIDE COTRANSPORTER-LIKE symporter activity#GO:0015293;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 localization#GO:0051179;monoatomic cation transport#GO:0006812;sodium ion transport#GO:0006814;metal ion transport#GO:0030001;establishment of localization#GO:0051234;monoatomic ion transport#GO:0006811;transport#GO:0006810 secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000015628.2|UniProtKB=F6UQG4 F6UQG4 PTHR23503:SF8 SOLUTE CARRIER FAMILY 2 FACILITATED GLUCOSE TRANSPORTER PROTEIN 1 transmembrane transporter activity#GO:0022857;sugar transmembrane transporter activity#GO:0051119;transporter activity#GO:0005215;carbohydrate transmembrane transporter activity#GO:0015144 localization#GO:0051179;organic substance transport#GO:0071702;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810;cellular process#GO:0009987;carbohydrate transmembrane transport#GO:0034219;carbohydrate transport#GO:0008643 cellular anatomical entity#GO:0110165;membrane#GO:0016020 secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000009357.3|UniProtKB=F6XKQ1 F6XKQ1 PTHR43327:SF10 STOMATIN-LIKE PROTEIN 2, MITOCHONDRIAL STOMATIN-LIKE PROTEIN 2, MITOCHONDRIAL transporter#PC00227 CIOIN|Ensembl=ENSCING00000001543.3|UniProtKB=F6YKT9 F6YKT9 PTHR43884:SF9 ACYL-COA DEHYDROGENASE COMPLEX I ASSEMBLY FACTOR ACAD9, MITOCHONDRIAL oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 dehydrogenase#PC00092;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000020227.1|UniProtKB=H2XMF7 H2XMF7 PTHR12081:SF18 TRANSCRIPTION FACTOR E2F TRANSCRIPTION FACTOR E2F2-RELATED sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 p53 pathway feedback loops 2#P04398>E2F-1#P04652;p53 pathway#P00059>E2F-1#P04627;Cell cycle#P00013>E2F#P00488 CIOIN|Ensembl=ENSCING00000005159.3|UniProtKB=F6PZT9 F6PZT9 LOC100185334 PTHR21443:SF0 CONSERVED OLIGOMERIC GOLGI COMPLEX COMPONENT 7 CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 7 localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;Golgi organization#GO:0007030;establishment of localization#GO:0051234;organelle organization#GO:0006996;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;transport#GO:0006810;endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;vesicle tethering complex#GO:0099023;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;Golgi transport complex#GO:0017119;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000009376.3|UniProtKB=F6WXC5 F6WXC5 klp2 PTHR24115:SF1004 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF15 pyrophosphatase activity#GO:0016462;cytoskeletal protein binding#GO:0008092;microtubule motor activity#GO:0003777;tubulin binding#GO:0015631;ATP-dependent activity#GO:0140657;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;cytoskeletal motor activity#GO:0003774;microtubule binding#GO:0008017;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;ribonucleoside triphosphate phosphatase activity#GO:0017111;ATP hydrolysis activity#GO:0016887 microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;microtubule associated complex#GO:0005875;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 CIOIN|Ensembl=ENSCING00000008143.3|UniProtKB=F6VG38 F6VG38 LOC100177362 PTHR11247:SF8 PALMITOYL-PROTEIN THIOESTERASE/DOLICHYLDIPHOSPHATASE 1 PALMITOYL-PROTEIN THIOESTERASE 1 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;thiolester hydrolase activity#GO:0016790 cytoplasm#GO:0005737;lysosome#GO:0005764;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;lytic vacuole#GO:0000323;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000020673.1|UniProtKB=H2Y017 H2Y017 PTHR31800:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 32 COILED-COIL DOMAIN-CONTAINING PROTEIN 32 cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782;cellular component organization#GO:0016043;cellular process#GO:0009987;cell projection organization#GO:0030030;organelle organization#GO:0006996;plasma membrane bounded cell projection organization#GO:0120036 CIOIN|Ensembl=ENSCING00000007342.3|UniProtKB=F6XYQ4 F6XYQ4 LOC100180339 PTHR34341:SF1 TRANSMEMBRANE PROTEIN 107 TRANSMEMBRANE PROTEIN 107 cellular component assembly#GO:0022607;non-motile cilium assembly#GO:1905515;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;cilium assembly#GO:0060271;macromolecule localization#GO:0033036;cell projection organization#GO:0030030;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031;protein localization#GO:0008104;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;protein localization to cilium#GO:0061512;organelle organization#GO:0006996;protein localization to organelle#GO:0033365;plasma membrane bounded cell projection assembly#GO:0120031 protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;cilium#GO:0005929;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;ciliary transition zone#GO:0035869 CIOIN|Ensembl=ENSCING00000012017.2|UniProtKB=Q1RLC3 Q1RLC3 Ci-ZF(TRAF_RING)-4 PTHR23059:SF4 CYSTEINE AND HISTIDINE-RICH PROTEIN 1 ZINC FINGER TRAF-TYPE-CONTAINING PROTEIN 1 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000012557.2|UniProtKB=F7AAS8 F7AAS8 LOC100184963 PTHR11153:SF14 SIDEROFLEXIN SIDEROFLEXIN-2 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 neutral amino acid transport#GO:0015804;transmembrane transport#GO:0055085;organic anion transport#GO:0015711;amino acid transport#GO:0006865;organic acid transport#GO:0015849;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942;cellular process#GO:0009987;carboxylic acid transmembrane transport#GO:1905039;mitochondrial transport#GO:0006839;localization#GO:0051179;organic substance transport#GO:0071702;amino acid transmembrane transport#GO:0003333;establishment of localization#GO:0051234;organic acid transmembrane transport#GO:1903825;mitochondrial transmembrane transport#GO:1990542 envelope#GO:0031975;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;organelle membrane#GO:0031090;organelle inner membrane#GO:0019866;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227 primary active transporter#PC00068;transporter#PC00227 CIOIN|Ensembl=ENSCING00000007593.3|UniProtKB=F7A367 F7A367 LOC100183005 PTHR46458:SF1 BLR2807 PROTEIN GEO09476P1 transporter#PC00227 CIOIN|Ensembl=ENSCING00000019868.1|UniProtKB=H2XVH9 H2XVH9 PTHR24353:SF147 CYCLIC NUCLEOTIDE-DEPENDENT PROTEIN KINASE CGMP-DEPENDENT SERINE_THREONIN PROTEIN KINASE-RELATED non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Endothelin signaling pathway#P00019>PKG#P00567 CIOIN|Ensembl=ENSCING00000020767.1|UniProtKB=H2XM03 H2XM03 PTHR47160:SF5 PUTATIVE-RELATED MULE TRANSPOSASE DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000013723.2|UniProtKB=F6PMJ3 F6PMJ3 PTHR48051:SF36 FAMILY NOT NAMED CASPASE FAMILY P20 DOMAIN-CONTAINING PROTEIN cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000007335.3|UniProtKB=F6YJQ4 F6YJQ4 LOC100185212 PTHR31698:SF7 LYSOZYME G FAMILY MEMBER PEPTIDASE M15C DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000013927.2|UniProtKB=F6PQC6 F6PQC6 PTHR12002:SF116 CLAUDIN CLAUDIN-11-LIKE cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cell-cell junction organization#GO:0045216;cellular component biogenesis#GO:0044085;cell-cell junction assembly#GO:0007043;cell junction organization#GO:0034330;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;cell adhesion#GO:0007155;cellular process#GO:0009987 tight junction#GO:0070160;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cell junction#GO:0030054;bicellular tight junction#GO:0005923;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;apical junction complex#GO:0043296;plasma membrane#GO:0005886 cell junction protein#PC00070;tight junction#PC00214 CIOIN|Ensembl=ENSCING00000006857.3|UniProtKB=A0A1W3JJK5 A0A1W3JJK5 LOC100186388 PTHR16220:SF0 WD REPEAT PROTEIN 8-RELATED WD REPEAT-CONTAINING PROTEIN WRAP73 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;nuclear chromosome segregation#GO:0098813;mitotic spindle organization#GO:0007052;sister chromatid segregation#GO:0000819;nuclear division#GO:0000280;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;cellular component organization#GO:0016043;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cellular process#GO:0009987;mitotic cell cycle process#GO:1903047;chromosome segregation#GO:0007059;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;microtubule-based process#GO:0007017;organelle organization#GO:0006996;chromosome organization#GO:0051276;mitotic spindle assembly#GO:0090307;spindle assembly#GO:0051225;cell cycle#GO:0007049;mitotic nuclear division#GO:0140014;organelle fission#GO:0048285;cytoskeleton organization#GO:0007010;spindle organization#GO:0007051;mitotic sister chromatid segregation#GO:0000070;non-membrane-bounded organelle assembly#GO:0140694 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000004063.3|UniProtKB=F7B6U2 F7B6U2 LOC100185246 PTHR24173:SF89 ANKYRIN REPEAT CONTAINING ANKYRIN REPEAT DOMAIN 29 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000001151.3|UniProtKB=F6YUM8 F6YUM8 PTHR19277:SF125 PENTRAXIN B6 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000006932.3|UniProtKB=F6VNW9 F6VNW9 LOC100180827 PTHR11742:SF55 MANNOSYL-OLIGOSACCHARIDE ALPHA-1,2-MANNOSIDASE-RELATED ENDOPLASMIC RETICULUM MANNOSYL-OLIGOSACCHARIDE 1,2-ALPHA-MANNOSIDASE hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 carbohydrate derivative metabolic process#GO:1901135;macromolecule modification#GO:0043412;protein catabolic process#GO:0030163;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;glycoprotein metabolic process#GO:0009100;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;macromolecule catabolic process#GO:0009057;response to endoplasmic reticulum stress#GO:0034976;response to oxygen-containing compound#GO:1901700;macromolecule metabolic process#GO:0043170;carbohydrate derivative catabolic process#GO:1901136;organonitrogen compound metabolic process#GO:1901564;ERAD pathway#GO:0036503;response to organonitrogen compound#GO:0010243;cellular process#GO:0009987;primary metabolic process#GO:0044238;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;cellular response to stress#GO:0033554 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000004973.3|UniProtKB=F6X915 F6X915 LOC100184659 PTHR10343:SF84 5'-AMP-ACTIVATED PROTEIN KINASE , BETA SUBUNIT 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT BETA-1 kinase modulator#PC00140 Gonadotropin-releasing hormone receptor pathway#P06664>AMPK#P06830;p53 pathway by glucose deprivation#P04397>AMPK#P04639 CIOIN|Ensembl=ENSCING00000016737.2|UniProtKB=F6QZW1 F6QZW1 PTHR48033:SF10 RNA-BINDING (RRM/RBD/RNP MOTIFS) FAMILY PROTEIN RNA-BINDING PROTEIN SQUID nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of biosynthetic process#GO:0009889;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000004052.3|UniProtKB=H2XRP0 H2XRP0 LOC100183487 PTHR39313:SF1 IM:7138239 IM:7138239 CIOIN|Ensembl=ENSCING00000023803.1|UniProtKB=H2XJN9 H2XJN9 LOC100181474 PTHR11092:SF0 SUGAR NUCLEOTIDE EPIMERASE RELATED EPIMERASE FAMILY PROTEIN SDR39U1 epimerase/racemase#PC00096;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000019092.1|UniProtKB=H2XPX9 H2XPX9 LOC100181401 PTHR11227:SF29 WD-REPEAT PROTEIN INTERACTING WITH PHOSPHOINOSIDES WIPI -RELATED WD REPEAT DOMAIN PHOSPHOINOSITIDE-INTERACTING PROTEIN 4 phosphatidylinositol-3-phosphate binding#GO:0032266;phosphatidylinositol bisphosphate binding#GO:1902936;small molecule binding#GO:0036094;binding#GO:0005488;lipid binding#GO:0008289;phosphatidylinositol binding#GO:0035091;anion binding#GO:0043168;ion binding#GO:0043167;phospholipid binding#GO:0005543;phosphatidylinositol phosphate binding#GO:1901981 cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;macroautophagy#GO:0016236;macromolecule localization#GO:0033036;macromolecule modification#GO:0043412;protein modification process#GO:0036211;autophagy of mitochondrion#GO:0000422;biosynthetic process#GO:0009058;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;cellular component disassembly#GO:0022411;nitrogen compound metabolic process#GO:0006807;catabolic process#GO:0009056;mitochondrion organization#GO:0007005;protein metabolic process#GO:0019538;protein lipidation#GO:0006497;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;cellular component assembly#GO:0022607;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organelle disassembly#GO:1903008;lipoprotein biosynthetic process#GO:0042158;protein localization#GO:0008104;primary metabolic process#GO:0044238;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;organelle organization#GO:0006996;autophagosome assembly#GO:0000045;lipoprotein metabolic process#GO:0042157;autophagy#GO:0006914 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;phagophore assembly site#GO:0000407;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;extrinsic component of membrane#GO:0019898 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000023634.1|UniProtKB=H2XPX8 H2XPX8 PTHR16134:SF119 F-BOX/TPR REPEAT PROTEIN POF3 AT02038P-RELATED ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000024784.1|UniProtKB=H2Y179 H2Y179 zf(c2h2)-49 PTHR46105:SF5 AGAP004733-PA ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 44 ISOFORM X1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 CIOIN|Ensembl=ENSCING00000013412.2|UniProtKB=F6V3X8 F6V3X8 PTHR22802:SF464 C-TYPE LECTIN SUPERFAMILY MEMBER ASIALOGLYCOPROTEIN RECEPTOR 1-LIKE ISOFORM X1 membrane traffic protein#PC00150 CIOIN|Ensembl=ENSCING00000024899.1|UniProtKB=H2XSQ5 H2XSQ5 PTHR11640:SF136 NEPHRIN NEPHRIN cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;binding#GO:0005488 cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987 cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;plasma membrane#GO:0005886 immunoglobulin superfamily cell adhesion molecule#PC00125;cell adhesion molecule#PC00069 CIOIN|Ensembl=ENSCING00000005547.3|UniProtKB=F6XEC9 F6XEC9 PTHR10845:SF259 REGULATOR OF G PROTEIN SIGNALING RGS DOMAIN-CONTAINING PROTEIN-RELATED G-protein modulator#PC00022;protein-binding activity modulator#PC00095;GTPase-activating protein#PC00257 CIOIN|Ensembl=ENSCING00000000012.3|UniProtKB=Q1RL21 Q1RL21 Ci-ZicL-1 PTHR19818:SF139 ZINC FINGER PROTEIN ZIC AND GLI PAIR-RULE PROTEIN ODD-PAIRED sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 CIOIN|Ensembl=ENSCING00000012897.2|UniProtKB=F6PTA9 F6PTA9 LOC100178053 PTHR45828:SF50 CYTOCHROME B561/FERRIC REDUCTASE TRANSMEMBRANE MUCIN-5AC-LIKE ISOFORM X1 cellular anatomical entity#GO:0110165;membrane#GO:0016020 reductase#PC00198;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000006993.3|UniProtKB=F6SBE5 F6SBE5 PTHR10075:SF100 BASIGIN RELATED FASCICLIN-2 cell adhesion molecule binding#GO:0050839;cell-cell adhesion mediator activity#GO:0098632;protein binding#GO:0005515;binding#GO:0005488 neuron projection guidance#GO:0097485;cell recognition#GO:0008037;neurogenesis#GO:0022008;cell projection organization#GO:0030030;developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cellular anatomical entity morphogenesis#GO:0032989;system development#GO:0048731;cell differentiation#GO:0030154;axon guidance#GO:0007411;anatomical structure morphogenesis#GO:0009653;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;axonogenesis#GO:0007409;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;homophilic cell adhesion via plasma membrane adhesion molecules#GO:0007156;cell-cell adhesion via plasma-membrane adhesion molecules#GO:0098742;cell-cell adhesion#GO:0098609;cellular component organization#GO:0016043;cell adhesion#GO:0007155;cell morphogenesis#GO:0000902;cellular process#GO:0009987;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;cell morphogenesis involved in neuron differentiation#GO:0048667;anatomical structure development#GO:0048856;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699 neuron projection#GO:0043005;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886;axon#GO:0030424 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000014373.2|UniProtKB=F7AG40 F7AG40 PTHR22923:SF116 CEREBELLIN-RELATED C1Q DOMAIN-CONTAINING PROTEIN scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000023909.1|UniProtKB=H2XNU9 H2XNU9 PTHR10174:SF200 ALPHA-TOCOPHEROL TRANSFER PROTEIN-RELATED RETINALDEHYDE-BINDING PROTEIN 1 phosphatidylinositol bisphosphate binding#GO:1902936;lipid binding#GO:0008289;phosphatidylinositol binding#GO:0035091;phospholipid binding#GO:0005543;phosphatidylinositol phosphate binding#GO:1901981;binding#GO:0005488 cellular anatomical entity#GO:0110165;membrane#GO:0016020 transfer/carrier protein#PC00219 CIOIN|Ensembl=ENSCING00000021551.1|UniProtKB=H2XRV4 H2XRV4 PTHR14191:SF29 PDZ DOMAIN CONTAINING PROTEIN PDZ DOMAIN-CONTAINING PROTEIN protein-membrane adaptor activity#GO:0043495;molecular adaptor activity#GO:0060090;protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102;protein-macromolecule adaptor activity#GO:0030674 localization#GO:0051179;protein localization to plasma membrane#GO:0072659;protein localization to cell periphery#GO:1990778;localization within membrane#GO:0051668;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;protein localization to membrane#GO:0072657;cellular process#GO:0009987;protein localization#GO:0008104 plasma membrane region#GO:0098590;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;apical part of cell#GO:0045177;plasma membrane#GO:0005886;apical plasma membrane#GO:0016324 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000021546.1|UniProtKB=F6YJ55 F6YJ55 PTHR11785:SF389 AMINO ACID TRANSPORTER Y+L AMINO ACID TRANSPORTER 1-LIKE L-amino acid transmembrane transporter activity#GO:0015179;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;amino acid transmembrane transporter activity#GO:0015171;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215;organic acid transmembrane transporter activity#GO:0005342 localization#GO:0051179;organic substance transport#GO:0071702;amino acid transmembrane transport#GO:0003333;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;amino acid transport#GO:0006865;organic anion transport#GO:0015711;organic acid transport#GO:0015849;transport#GO:0006810;nitrogen compound transport#GO:0071705;organic acid transmembrane transport#GO:1903825;carboxylic acid transport#GO:0046942;cellular process#GO:0009987;carboxylic acid transmembrane transport#GO:1905039 transporter#PC00227 CIOIN|Ensembl=ENSCING00000019066.1|UniProtKB=H2XTV9 H2XTV9 PTHR13449:SF2 INTEGRAL MEMBRANE PROTEIN GPR177 PROTEIN WNTLESS HOMOLOG protein binding#GO:0005515;Wnt-protein binding#GO:0017147;binding#GO:0005488 cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;nitrogen compound transport#GO:0071705;protein secretion#GO:0009306;cell communication#GO:0007154;cell-cell signaling by wnt#GO:0198738;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;regulation of biological process#GO:0050789;establishment of protein localization to extracellular region#GO:0035592;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;secretion#GO:0046903;protein transport#GO:0015031;biological regulation#GO:0065007;signal release#GO:0023061;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;protein localization to extracellular region#GO:0071692;cell-cell signaling#GO:0007267;signaling#GO:0023052;export from cell#GO:0140352;secretion by cell#GO:0032940 membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endomembrane system#GO:0012505 CIOIN|Ensembl=ENSCING00000002858.3|UniProtKB=F6WA81 F6WA81 PTHR18896:SF76 PHOSPHOLIPASE D PHOSPHOLIPASE hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;phosphoric diester hydrolase activity#GO:0008081;phospholipase activity#GO:0004620;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 lipid metabolic process#GO:0006629;cellular metabolic process#GO:0044237;lipid catabolic process#GO:0016042;cellular process#GO:0009987;phospholipid metabolic process#GO:0006644;phosphorus metabolic process#GO:0006793;organophosphate catabolic process#GO:0046434;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;phospholipid catabolic process#GO:0009395;catabolic process#GO:0009056;organophosphate metabolic process#GO:0019637;organic substance catabolic process#GO:1901575;cellular lipid metabolic process#GO:0044255;cellular lipid catabolic process#GO:0044242;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 phospholipase#PC00186 Angiogenesis#P00005>PLD#P00204 CIOIN|Ensembl=ENSCING00000023267.1|UniProtKB=H2XRK5 H2XRK5 PTHR45704:SF19 RAS-LIKE FAMILY MEMBER 11 RAS LIKE ESTROGEN REGULATED GROWTH INHIBITOR CIOIN|Ensembl=ENSCING00000021695.1|UniProtKB=H2XZY0 H2XZY0 PTHR10615:SF82 HISTONE ACETYLTRANSFERASE HISTONE ACETYLTRANSFERASE KAT8 histone modifying activity#GO:0140993;histone acetyltransferase activity#GO:0004402;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;N-acetyltransferase activity#GO:0008080;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acetyltransferase activity#GO:0016407;peptide-lysine-N-acetyltransferase activity#GO:0061733;peptide N-acetyltransferase activity#GO:0034212;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;N-acyltransferase activity#GO:0016410 histone acetyltransferase complex#GO:0000123;acetyltransferase complex#GO:1902493;protein-DNA complex#GO:0032993;chromatin#GO:0000785;catalytic complex#GO:1902494;NuA4 histone acetyltransferase complex#GO:0035267;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein acetyltransferase complex#GO:0031248;protein-containing complex#GO:0032991;chromosome#GO:0005694 chromatin/chromatin-binding, or -regulatory protein#PC00077;histone modifying enzyme#PC00261 CIOIN|Ensembl=ENSCING00000006754.3|UniProtKB=F6Y070 F6Y070 PTHR10361:SF19 SODIUM-BILE ACID COTRANSPORTER ILEAL SODIUM_BILE ACID COTRANSPORTER secondary active monocarboxylate transmembrane transporter activity#GO:0015355;inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;organic acid:sodium symporter activity#GO:0005343;organic acid transmembrane transporter activity#GO:0005342;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;bile acid transmembrane transporter activity#GO:0015125;organic anion transmembrane transporter activity#GO:0008514;monoatomic cation transmembrane transporter activity#GO:0008324;active transmembrane transporter activity#GO:0022804;lipid transporter activity#GO:0005319;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;metal ion transmembrane transporter activity#GO:0046873;active monoatomic ion transmembrane transporter activity#GO:0022853;monocarboxylic acid transmembrane transporter activity#GO:0008028;inorganic cation transmembrane transporter activity#GO:0022890;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294 localization#GO:0051179;organic hydroxy compound transport#GO:0015850;organic substance transport#GO:0071702;monocarboxylic acid transport#GO:0015718;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;organic anion transport#GO:0015711;organic acid transport#GO:0015849;transport#GO:0006810;carboxylic acid transport#GO:0046942;lipid localization#GO:0010876;bile acid and bile salt transport#GO:0015721;lipid transport#GO:0006869 primary active transporter#PC00068;transporter#PC00227 CIOIN|Ensembl=ENSCING00000022676.1|UniProtKB=H2Y033 H2Y033 LOC100182342 PTHR24064:SF577 SOLUTE CARRIER FAMILY 22 MEMBER GH09241P secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000002211.3|UniProtKB=F6ZPV8 F6ZPV8 LOC100181032 PTHR42808:SF3 HYDROXYSTEROID DEHYDROGENASE-LIKE PROTEIN 2 HYDROXYSTEROID DEHYDROGENASE-LIKE PROTEIN 2 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000019861.1|UniProtKB=H2XMT5 H2XMT5 LOC100180671 PTHR12119:SF2 UBIQUINOL-CYTOCHROME C REDUCTASE COMPLEX UBIQUINONE-BINDING PROTEIN QP-C CYTOCHROME B-C1 COMPLEX SUBUNIT 8 mitochondrial ATP synthesis coupled electron transport#GO:0042775;aerobic respiration#GO:0009060;cellular respiration#GO:0045333;respiratory electron transport chain#GO:0022904;aerobic electron transport chain#GO:0019646;oxidative phosphorylation#GO:0006119;generation of precursor metabolites and energy#GO:0006091;electron transport chain#GO:0022900;ATP synthesis coupled electron transport#GO:0042773;cellular metabolic process#GO:0044237;mitochondrial electron transport, ubiquinol to cytochrome c#GO:0006122;cellular process#GO:0009987;energy derivation by oxidation of organic compounds#GO:0015980;metabolic process#GO:0008152 envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;cytochrome complex#GO:0070069;respiratory chain complex#GO:0098803;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transporter complex#GO:1990351;oxidoreductase complex#GO:1990204;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;respirasome#GO:0070469;protein-containing complex#GO:0032991;mitochondrial envelope#GO:0005740;mitochondrial respirasome#GO:0005746;transmembrane transporter complex#GO:1902495;inner mitochondrial membrane protein complex#GO:0098800;mitochondrial respiratory chain complex III#GO:0005750;membrane-bounded organelle#GO:0043227;mitochondrial protein-containing complex#GO:0098798 oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000015730.2|UniProtKB=F6VWA2 F6VWA2 LOC100179709 PTHR23143:SF30 TRICHOHYALIN-RELATED SPERMATID ASSOCIATED LIKE actin or actin-binding cytoskeletal protein#PC00041 CIOIN|Ensembl=ENSCING00000004523.3|UniProtKB=F7A9I0 F7A9I0 LOC100179477 PTHR24372:SF77 GLYCOPROTEIN HORMONE RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 response to organic substance#GO:0010033;positive regulation of adenylate cyclase activity#GO:0045762;regulation of lyase activity#GO:0051339;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;cellular response to stimulus#GO:0051716;regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;cellular response to endogenous stimulus#GO:0071495;cellular response to chemical stimulus#GO:0070887;positive regulation of catalytic activity#GO:0043085;cellular response to organic substance#GO:0071310;regulation of cyclase activity#GO:0031279;positive regulation of molecular function#GO:0044093;cell communication#GO:0007154;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;positive regulation of cyclase activity#GO:0031281;hormone-mediated signaling pathway#GO:0009755;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to endogenous stimulus#GO:0009719;response to hormone#GO:0009725;cellular response to hormone stimulus#GO:0032870;response to chemical#GO:0042221;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of lyase activity#GO:0051349;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 CIOIN|Ensembl=ENSCING00000006155.3|UniProtKB=F6SEC8 F6SEC8 LOC100176358 PTHR11786:SF0 N-HYDROXYARYLAMINE O-ACETYLTRANSFERASE ARYLAMINE N-ACETYLTRANSFERASE 4-RELATED acetyltransferase#PC00038 CIOIN|Ensembl=ENSCING00000012592.2|UniProtKB=F6T6N4 F6T6N4 LOC100179909 PTHR12411:SF917 CYSTEINE PROTEASE FAMILY C1-RELATED CATHEPSIN L cysteine-type peptidase activity#GO:0008234;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197 macromolecule catabolic process#GO:0009057;nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;proteolysis#GO:0006508;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;catabolic process#GO:0009056;organonitrogen compound catabolic process#GO:1901565;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;primary metabolic process#GO:0044238 cytoplasm#GO:0005737;lysosome#GO:0005764;intracellular membrane-bounded organelle#GO:0043231;extracellular region#GO:0005576;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;organelle#GO:0043226;lytic vacuole#GO:0000323;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cysteine protease#PC00081;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000000730.3|UniProtKB=A0A1W3JNV5 A0A1W3JNV5 LOC100186361 PTHR10715:SF0 60S RIBOSOMAL PROTEIN L6 LARGE RIBOSOMAL SUBUNIT PROTEIN EL6 structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;structural molecule activity#GO:0005198;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular component biogenesis#GO:0044085;peptide metabolic process#GO:0006518;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;ribosomal large subunit biogenesis#GO:0042273;translation#GO:0006412;protein-RNA complex assembly#GO:0022618;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;ribosomal large subunit assembly#GO:0000027;ribosome biogenesis#GO:0042254;non-membrane-bounded organelle assembly#GO:0140694;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular component assembly#GO:0022607;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cytoplasmic translation#GO:0002181;cellular component organization#GO:0016043;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;peptide biosynthetic process#GO:0043043;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;ribonucleoprotein complex biogenesis#GO:0022613;protein-RNA complex organization#GO:0071826 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic large ribosomal subunit#GO:0022625;large ribosomal subunit#GO:0015934;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000009647.3|UniProtKB=F6XHC0 F6XHC0 PTHR43571:SF1 NADP-SPECIFIC GLUTAMATE DEHYDROGENASE 1-RELATED NADP-SPECIFIC GLUTAMATE DEHYDROGENASE 1-RELATED oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;proteinogenic amino acid metabolic process#GO:0170039;dicarboxylic acid metabolic process#GO:0043648;proteinogenic amino acid biosynthetic process#GO:0170038;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;alpha-amino acid biosynthetic process#GO:1901607;nitrogen compound metabolic process#GO:0006807;glutamate metabolic process#GO:0006536;amino acid biosynthetic process#GO:0008652;alpha-amino acid metabolic process#GO:1901605;small molecule biosynthetic process#GO:0044283;L-amino acid biosynthetic process#GO:0170034;carboxylic acid metabolic process#GO:0019752;L-amino acid metabolic process#GO:0170033;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 dehydrogenase#PC00092;oxidoreductase#PC00176 Glutamine glutamate conversion#P02745>Glutamate Dehydrogenase#P02967 CIOIN|Ensembl=ENSCING00000002308.3|UniProtKB=F6PPC0 F6PPC0 PTHR43986:SF1 ELONGATION FACTOR 1-GAMMA ELONGATION FACTOR 1-GAMMA macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;translation#GO:0006412;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;translational elongation#GO:0006414;amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000008186.3|UniProtKB=H2XJF4 H2XJF4 LOC100187164 PTHR11680:SF59 SERINE HYDROXYMETHYLTRANSFERASE SERINE HYDROXYMETHYLTRANSFERASE, CYTOSOLIC transferase activity#GO:0016740;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;heterocyclic compound binding#GO:1901363;transferase activity, transferring one-carbon groups#GO:0016741;anion binding#GO:0043168;ion binding#GO:0043167 cellular aromatic compound metabolic process#GO:0006725;organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;proteinogenic amino acid metabolic process#GO:0170039;heterocycle metabolic process#GO:0046483;proteinogenic amino acid biosynthetic process#GO:0170038;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;folic acid-containing compound metabolic process#GO:0006760;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;organic cyclic compound metabolic process#GO:1901360;alpha-amino acid biosynthetic process#GO:1901607;nitrogen compound metabolic process#GO:0006807;cellular modified amino acid metabolic process#GO:0006575;amino acid biosynthetic process#GO:0008652;alpha-amino acid metabolic process#GO:1901605;small molecule biosynthetic process#GO:0044283;L-amino acid biosynthetic process#GO:0170034;carboxylic acid metabolic process#GO:0019752;L-amino acid metabolic process#GO:0170033;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 methyltransferase#PC00155;metabolite interconversion enzyme#PC00262 Serine glycine biosynthesis#P02776>Glycine hydroxymethyltransferase#P03158 CIOIN|Ensembl=ENSCING00000013532.2|UniProtKB=F6YW02 F6YW02 PTHR10961:SF46 PEROXISOMAL SARCOSINE OXIDASE PEROXISOMAL SARCOSINE OXIDASE oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 oxidase#PC00175;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000004918.3|UniProtKB=F7B8Z4 F7B8Z4 LOC100175260 PTHR10358:SF6 ENDOSULFINE ENDOSULFINE, ISOFORM A phosphatase regulator activity#GO:0019208;molecular function regulator activity#GO:0098772;protein phosphatase regulator activity#GO:0019888;enzyme inhibitor activity#GO:0004857;phosphatase inhibitor activity#GO:0019212;molecular function inhibitor activity#GO:0140678;protein phosphatase inhibitor activity#GO:0004864;enzyme regulator activity#GO:0030234 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of phosphorus metabolic process#GO:0010563;regulation of dephosphorylation#GO:0035303;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of nitrogen compound metabolic process#GO:0051172;regulation of phosphorus metabolic process#GO:0051174;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;negative regulation of protein modification process#GO:0031400;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of phosphate metabolic process#GO:0045936;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000008611.3|UniProtKB=F6TNV1 F6TNV1 LOC100186500 PTHR24248:SF129 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 CIOIN|Gene_ORFName=ciad093d18|UniProtKB=Q4H2R2 Q4H2R2 SSRP1 PTHR45849:SF1 FACT COMPLEX SUBUNIT SSRP1 FACT COMPLEX SUBUNIT SSRP1 nucleosome binding#GO:0031491;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;chromatin binding#GO:0003682;histone binding#GO:0042393 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-DNA complex#GO:0032993;chromatin#GO:0000785;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;transcription elongation factor complex#GO:0008023;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 CIOIN|Ensembl=ENSCING00000013372.2|UniProtKB=A0A1W3JPN0 A0A1W3JPN0 LOC100182282 PTHR24104:SF59 E3 UBIQUITIN-PROTEIN LIGASE NHLRC1-RELATED TRIPARTITE MOTIF-CONTAINING PROTEIN 2-LIKE transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein polyubiquitination#GO:0000209;proteasomal protein catabolic process#GO:0010498;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000011370.2|UniProtKB=F6V693 F6V693 PTHR42985:SF45 SODIUM-COUPLED MONOCARBOXYLATE TRANSPORTER SODIUM_IODIDE COTRANSPORTER-LIKE symporter activity#GO:0015293;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 localization#GO:0051179;monoatomic cation transport#GO:0006812;sodium ion transport#GO:0006814;metal ion transport#GO:0030001;establishment of localization#GO:0051234;monoatomic ion transport#GO:0006811;transport#GO:0006810 secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000021850.1|UniProtKB=H2XY06 H2XY06 PTHR35249:SF2 DYNEIN REGULATORY COMPLEX SUBUNIT 7 DYNEIN REGULATORY COMPLEX SUBUNIT 7 cell motility#GO:0048870;cellular process#GO:0009987 membrane-bounded organelle#GO:0043227;motile cilium#GO:0031514;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;cilium#GO:0005929;organelle#GO:0043226 cytoskeletal protein#PC00085;microtubule or microtubule-binding cytoskeletal protein#PC00157 CIOIN|Ensembl=ENSCING00000003992.3|UniProtKB=F6VYK8 F6VYK8 PTHR11485:SF29 TRANSFERRIN TRANSFERRIN 2 localization#GO:0051179;metal ion transport#GO:0030001;establishment of localization#GO:0051234;transport#GO:0006810;monoatomic cation transport#GO:0006812;iron ion transport#GO:0006826;transition metal ion transport#GO:0000041;monoatomic ion transport#GO:0006811 endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;extracellular region#GO:0005576;early endosome#GO:0005769;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;endomembrane system#GO:0012505;recycling endosome#GO:0055037;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;plasma membrane#GO:0005886 transfer/carrier protein#PC00219 CIOIN|Ensembl=ENSCING00000003601.3|UniProtKB=F6UY72 F6UY72 PTHR12552:SF1 OLIGOPHRENIN 1 RHO GTPASE-ACTIVATING PROTEIN GRAF nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047;GTPase regulator activity#GO:0030695;molecular function activator activity#GO:0140677;GTPase activator activity#GO:0005096;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234 protein-binding activity modulator#PC00095;GTPase-activating protein#PC00257 PDGF signaling pathway#P00047>Rho#P01174 CIOIN|Ensembl=ENSCING00000012217.2|UniProtKB=F7BP46 F7BP46 LOC100183612 PTHR13064:SF6 TRANSMEMBRANE PROTEIN 9 FAMILY MEMBER TRANSMEMBRANE PROTEIN 9 CIOIN|Ensembl=ENSCING00000025065.1|UniProtKB=H2XW58 H2XW58 PTHR13869:SF24 MYELIN P0 RELATED BASEMENT MEMBRANE-SPECIFIC HEPARAN SULFATE PROTEOGLYCAN CORE PROTEIN-LIKE myelin protein#PC00161;structural protein#PC00211 CIOIN|Ensembl=ENSCING00000019922.1|UniProtKB=Q9NDP3 Q9NDP3 Ci-Not7 PTHR11969:SF54 MAX DIMERIZATION, MAD MAD-LIKE PROTEIN 1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 basic helix-loop-helix transcription factor#PC00055 CIOIN|Ensembl=ENSCING00000015322.2|UniProtKB=F6PKA8 F6PKA8 PTHR45753:SF6 ORNITHINE CARBAMOYLTRANSFERASE, MITOCHONDRIAL ASPARTATE CARBAMOYLTRANSFERASE transferase#PC00220;metabolite interconversion enzyme#PC00262 De novo pyrimidine ribonucleotides biosythesis#P02740>Aspartate carbamoyltransferase#P02926 CIOIN|Ensembl=ENSCING00000020642.1|UniProtKB=H2XP05 H2XP05 LOC100182967 PTHR11576:SF14 ZONA PELLUCIDA SPERM-BINDING PROTEIN 3 ZP DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000005281.3|UniProtKB=F6UIC9 F6UIC9 LOC100182107 PTHR10504:SF131 BACTERICIDAL PERMEABILITY-INCREASING BPI PROTEIN-RELATED BPI2 DOMAIN-CONTAINING PROTEIN defense/immunity protein#PC00090 CIOIN|Ensembl=ENSCING00000007471.2|UniProtKB=F6XXJ3 F6XXJ3 LOC100176282 PTHR21223:SF2 CBY1-INTERACTING BAR DOMAIN-CONTAINING PROTEIN HOMOLOG CBY1-INTERACTING BAR DOMAIN-CONTAINING PROTEIN HOMOLOG organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cell projection organization#GO:0030030;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;microtubule cytoskeleton#GO:0015630;ciliary basal body#GO:0036064;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cilium#GO:0005929;intracellular organelle#GO:0043229;ciliary transition zone#GO:0035869;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000003709.3|UniProtKB=A0A1W2W2Y7 A0A1W2W2Y7 LOC100180855 PTHR46989:SF3 USP DOMAIN-CONTAINING PROTEIN USPA DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000015007.2|UniProtKB=F6U7A5 F6U7A5 PTHR33887:SF6 PB1 DOMAIN-CONTAINING PROTEIN CIDE-N DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000020060.1|UniProtKB=H2XZX7 H2XZX7 PTHR20883:SF46 PHYTANOYL-COA DIOXYGENASE DOMAIN CONTAINING 1 PHYTANOYL-COA HYDROXYLASE oxygenase#PC00177;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000004057.3|UniProtKB=A0A1W2VZP0 A0A1W2VZP0 LOC100180332 PTHR16110:SF1 TBC1 DOMAIN FAMILY MEMBER 19 TBC1 DOMAIN FAMILY MEMBER 19 CIOIN|Ensembl=ENSCING00000014793.2|UniProtKB=F6VLD0 F6VLD0 PTHR21136:SF179 SNARE PROTEINS VESICLE ASSOCIATED MEMBRANE PROTEIN 7-RELATED molecular adaptor activity#GO:0060090;protein binding#GO:0005515;SNAP receptor activity#GO:0005484;binding#GO:0005488;SNARE binding#GO:0000149;protein-macromolecule adaptor activity#GO:0030674 vesicle fusion#GO:0006906;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;membrane fusion#GO:0061025;exocytosis#GO:0006887;establishment of localization#GO:0051234;secretion#GO:0046903;organelle organization#GO:0006996;vesicle organization#GO:0016050;export from cell#GO:0140352;organelle fusion#GO:0048284;secretion by cell#GO:0032940 SNARE complex#GO:0031201;cytoplasm#GO:0005737;membrane protein complex#GO:0098796;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;membrane#GO:0016020;intracellular anatomical structure#GO:0005622 SNARE protein#PC00034 CIOIN|Ensembl=ENSCING00000009098.3|UniProtKB=F6QDK5 F6QDK5 PTHR15422:SF45 OS05G0565100 PROTEIN CYTOCHROME B561 DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000013040.2|UniProtKB=F6TT01 F6TT01 LOC100179175 PTHR44340:SF1 DNAJ HOMOLOG SUBFAMILY C MEMBER 10 DNAJ HOMOLOG SUBFAMILY C MEMBER 10 protein-disulfide reductase activity#GO:0015035;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;binding#GO:0005488;catalytic activity#GO:0003824;protein binding#GO:0005515;disulfide oxidoreductase activity#GO:0015036;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491 response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;endoplasmic reticulum unfolded protein response#GO:0030968;response to endoplasmic reticulum stress#GO:0034976;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to topologically incorrect protein#GO:0035967;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;response to topologically incorrect protein#GO:0035966;response to unfolded protein#GO:0006986;cellular response to unfolded protein#GO:0034620;biological regulation#GO:0065007;cellular response to stress#GO:0033554;signaling#GO:0023052 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;endoplasmic reticulum lumen#GO:0005788;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chaperone#PC00072 CIOIN|Ensembl=ENSCING00000003939.3|UniProtKB=F6ZM08 F6ZM08 PTHR16777:SF2 PROTEIN ECT2 PROTEIN ECT2 cell division#GO:0051301;regulation of GTPase activity#GO:0043087;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;developmental process#GO:0032502;multicellular organism development#GO:0007275;activation of GTPase activity#GO:0090630;cell cycle process#GO:0022402;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;nervous system development#GO:0007399;mitotic cell cycle process#GO:1903047;positive regulation of hydrolase activity#GO:0051345;system development#GO:0048731;mitotic cytokinesis#GO:0000281;mitotic cell cycle#GO:0000278;regulation of molecular function#GO:0065009;anatomical structure development#GO:0048856;biological regulation#GO:0065007;cytoskeleton-dependent cytokinesis#GO:0061640;cell cycle#GO:0007049;multicellular organismal process#GO:0032501;regulation of hydrolase activity#GO:0051336;cytokinesis#GO:0000910 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cell cortex#GO:0005938;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 CIOIN|Ensembl=ENSCING00000004147.3|UniProtKB=F6UHH9 F6UHH9 PTHR47958:SF150 ATP-DEPENDENT RNA HELICASE DBP3 ATP-DEPENDENT RNA HELICASE DDX17-RELATED catalytic activity, acting on RNA#GO:0140098;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;helicase activity#GO:0004386;ATP-dependent activity#GO:0140657;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;catalytic activity, acting on a nucleic acid#GO:0140640;mRNA binding#GO:0003729 cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA helicase#PC00032 CIOIN|Ensembl=ENSCING00000004180.4|UniProtKB=F7B580 F7B580 PTHR10947:SF0 PHENYLALANYL-TRNA SYNTHETASE BETA CHAIN AND LEUCINE-RICH REPEAT-CONTAINING PROTEIN 47 PHENYLALANINE--TRNA LIGASE BETA SUBUNIT catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;ligase activity#GO:0016874;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;peptide biosynthetic process#GO:0043043;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622 aminoacyl-tRNA synthetase#PC00047;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000025012.1|UniProtKB=H2XKH3 H2XKH3 PTHR10177:SF559 CYCLINS G2_MITOTIC-SPECIFIC CYCLIN-B protein kinase regulator activity#GO:0019887;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207 regulation of protein kinase activity#GO:0045859;regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;mitotic cell cycle phase transition#GO:0044772;regulation of nitrogen compound metabolic process#GO:0051171;cell cycle process#GO:0022402;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;cell cycle phase transition#GO:0044770;mitotic cell cycle process#GO:1903047;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;regulation of primary metabolic process#GO:0080090;mitotic cell cycle#GO:0000278;regulation of macromolecule metabolic process#GO:0060255;regulation of molecular function#GO:0065009;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;regulation of protein serine/threonine kinase activity#GO:0071900;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cyclin-dependent protein serine/threonine kinase activity#GO:0000079;regulation of kinase activity#GO:0043549;regulation of cellular metabolic process#GO:0031323 microtubule organizing center#GO:0005815;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;serine/threonine protein kinase complex#GO:1902554;protein kinase complex#GO:1902911;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856 kinase activator#PC00138 Cell cycle#P00013>Cyclin B#P00486;p53 pathway#P00059>Cyclin B#P04614 CIOIN|Gene=AXP83.9|UniProtKB=Q8T880 Q8T880 AXP83.9 PTHR20929:SF11 LUNG ADENOMA SUSCEPTIBILITY 1-RELATED DYNEIN AXONEMAL INTERMEDIATE CHAIN 7 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 axoneme#GO:0005930;cytoplasmic region#GO:0099568;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;plasma membrane bounded cell projection cytoplasm#GO:0032838;ciliary plasm#GO:0097014;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cytoskeleton#GO:0005856;cilium#GO:0005929 CIOIN|Ensembl=ENSCING00000006468.3|UniProtKB=F6Q2U2 F6Q2U2 PTHR12894:SF49 CNH DOMAIN CONTAINING VAM6_VPS39-LIKE PROTEIN vesicle fusion#GO:0006906;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;process utilizing autophagic mechanism#GO:0061919;cellular component organization or biogenesis#GO:0071840;membrane fusion#GO:0061025;establishment of localization#GO:0051234;organelle organization#GO:0006996;catabolic process#GO:0009056;vesicle organization#GO:0016050;autophagy#GO:0006914;organelle fusion#GO:0048284;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;membrane#GO:0016020;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000007552.3|UniProtKB=F6T8N0 F6T8N0 PTHR19325:SF567 COMPLEMENT COMPONENT-RELATED SUSHI DOMAIN-CONTAINING SUSHI, VON WILLEBRAND FACTOR TYPE A, EGF AND PENTRAXIN DOMAIN-CONTAINING PROTEIN 1-LIKE complement component#PC00078 CIOIN|Ensembl=ENSCING00000007379.3|UniProtKB=F6UM75 F6UM75 PTHR10569:SF2 GLYCOGEN DEBRANCHING ENZYME GLYCOGEN DEBRANCHING ENZYME glucosidase activity#GO:0015926;alpha-glucosidase activity#GO:0090599;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;hexosyltransferase activity#GO:0016758 glucan metabolic process#GO:0044042;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;glycogen metabolic process#GO:0005977;generation of precursor metabolites and energy#GO:0006091;cellular metabolic process#GO:0044237;cellular process#GO:0009987;energy derivation by oxidation of organic compounds#GO:0015980;primary metabolic process#GO:0044238;polysaccharide metabolic process#GO:0005976;carbohydrate catabolic process#GO:0016052;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;energy reserve metabolic process#GO:0006112;carbohydrate metabolic process#GO:0005975;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 CIOIN|Ensembl=ENSCING00000004951.3|UniProtKB=F7A6R2 F7A6R2 LOC113474994 PTHR28366:SF1 CHROMOSOME 1 OPEN READING FRAME 131 CHROMOSOME 1 OPEN READING FRAME 131 CIOIN|Ensembl=ENSCING00000004452.3|UniProtKB=F6XDT3 F6XDT3 LOC100175447 PTHR45769:SF3 ADENOSINE KINASE ADENOSINE KINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;purine nucleobase metabolic process#GO:0006144;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase metabolic process#GO:0009112;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;purine-containing compound metabolic process#GO:0072521;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000003388.3|UniProtKB=F7A655 F7A655 PTHR22906:SF43 PROPERDIN PROPERDIN CIOIN|Ensembl=ENSCING00000019303.1|UniProtKB=H2Y318 H2Y318 LOC100184903 PTHR19307:SF14 TUMOR PROTEIN D52 TUMOR PROTEIN D52 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000008035.3|UniProtKB=Q1RL83 Q1RL83 Ci-ZF(ZZ_RING)-1 PTHR24202:SF4 E3 UBIQUITIN-PROTEIN LIGASE MIB2 E3 UBIQUITIN-PROTEIN LIGASE MIB2-RELATED protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000004586.3|UniProtKB=F6XB46 F6XB46 PTHR12186:SF2 SIKE FAMILY MEMBER FGFR1 ONCOGENE PARTNER 2 HOMOLOG CIOIN|Ensembl=ENSCING00000024707.1|UniProtKB=H2XNV6 H2XNV6 PTHR21224:SF1 INTEGRATOR COMPLEX SUBUNIT 1 INTEGRATOR COMPLEX SUBUNIT 1 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;snRNA metabolic process#GO:0016073;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;snRNA 3'-end processing#GO:0034472;snRNA processing#GO:0016180;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;integrator complex#GO:0032039 CIOIN|Ensembl=ENSCING00000018949.1|UniProtKB=H2XKR1 H2XKR1 PTHR24329:SF543 HOMEOBOX PROTEIN ARISTALESS FI01017P-RELATED sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 CIOIN|Ensembl=ENSCING00000007493.3|UniProtKB=Q1RL89 Q1RL89 Ci-ZF(C2H2)-132 PTHR23235:SF120 KRUEPPEL-LIKE TRANSCRIPTION FACTOR KRUPPEL-LIKE FACTOR 15 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 CIOIN|Ensembl=ENSCING00000002330.3|UniProtKB=F6PNQ0 F6PNQ0 PTHR24072:SF359 RHO FAMILY GTPASE RAS-RELATED PROTEIN RAC1-RELATED GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;enzyme binding#GO:0019899;ribonucleoside triphosphate phosphatase activity#GO:0017111;kinase binding#GO:0019900;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;protein kinase binding#GO:0019901;anion binding#GO:0043168;ion binding#GO:0043167 establishment or maintenance of cell polarity#GO:0007163;regulation of anatomical structure morphogenesis#GO:0022603;regulation of organelle organization#GO:0033043;regulation of cellular component organization#GO:0051128;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of cytoskeleton organization#GO:0051493;regulation of cell shape#GO:0008360;regulation of biological quality#GO:0065008;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;cortical cytoskeleton organization#GO:0030865;biological regulation#GO:0065007;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;regulation of actin filament-based process#GO:0032970 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 small GTPase#PC00208 T cell activation#P00053>rac#P01324;Huntington disease#P00029>Rac#P00775;Cytoskeletal regulation by Rho GTPase#P00016>Rac#P00523;EGF receptor signaling pathway#P00018>Rac#P00564;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Cdc42#P00834;Ras Pathway#P04393>Rac#P04559;Axon guidance mediated by netrin#P00009>Rac#P00366;Integrin signalling pathway#P00034>Rac#P00927;Axon guidance mediated by Slit/Robo#P00008>Rac#P00354;FGF signaling pathway#P00021>Rac#P00645 CIOIN|Ensembl=ENSCING00000001085.3|UniProtKB=F7B012 F7B012 PTHR24068:SF143 UBIQUITIN-CONJUGATING ENZYME E2 GEO06356P1 ubiquitin-like protein conjugating enzyme activity#GO:0061650;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin conjugating enzyme activity#GO:0061631;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;protein ubiquitination#GO:0016567;cellular response to stimulus#GO:0051716;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;postreplication repair#GO:0006301;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;post-translational protein modification#GO:0043687;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;DNA damage response#GO:0006974;organic cyclic compound metabolic process#GO:1901360;response to stress#GO:0006950;nitrogen compound metabolic process#GO:0006807;protein polyubiquitination#GO:0000209;cellular response to stress#GO:0033554;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;protein K63-linked ubiquitination#GO:0070534;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 Toll receptor signaling pathway#P00054>Uev1A#P01376;Ubiquitin proteasome pathway#P00060>E2#P01491 CIOIN|Ensembl=ENSCING00000022683.1|UniProtKB=H2XL54 H2XL54 LOC100186976 PTHR10166:SF37 VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2/DELTA-RELATED STOLID, ISOFORM H ion channel#PC00133;transporter#PC00227;voltage-gated ion channel#PC00241 CIOIN|Ensembl=ENSCING00000007314.3|UniProtKB=F6Z3G2 F6Z3G2 PTHR12461:SF27 HYPOXIA-INDUCIBLE FACTOR 1 ALPHA INHIBITOR-RELATED JMJC DOMAIN-CONTAINING PROTEIN protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000006360.2|UniProtKB=F6RS86 F6RS86 LOC100180750 PTHR24291:SF189 CYTOCHROME P450 FAMILY 4 CYTOCHROME P450 4C3-RELATED oxygenase#PC00177;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000004454.3|UniProtKB=F6USY8 F6USY8 LOC100179839 PTHR46596:SF1 SORTING NEXIN-4 SORTING NEXIN-4 phosphatidylinositol-3-phosphate binding#GO:0032266;lipid binding#GO:0008289;phosphatidylinositol binding#GO:0035091;phospholipid binding#GO:0005543;phosphatidylinositol phosphate binding#GO:1901981;binding#GO:0005488 cellular localization#GO:0051641;positive regulation of organelle organization#GO:0010638;regulation of catabolic process#GO:0009894;macromolecule localization#GO:0033036;positive regulation of cellular metabolic process#GO:0031325;transport#GO:0006810;positive regulation of cellular catabolic process#GO:0031331;nitrogen compound transport#GO:0071705;regulation of cellular component organization#GO:0051128;establishment of protein localization#GO:0045184;regulation of biological process#GO:0050789;organic substance transport#GO:0071702;positive regulation of metabolic process#GO:0009893;establishment of localization#GO:0051234;regulation of cellular component biogenesis#GO:0044087;regulation of organelle assembly#GO:1902115;positive regulation of cellular component biogenesis#GO:0044089;positive regulation of biological process#GO:0048518;regulation of autophagy#GO:0010506;regulation of organelle organization#GO:0033043;regulation of macroautophagy#GO:0016241;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;protein localization#GO:0008104;positive regulation of cellular process#GO:0048522;localization#GO:0051179;positive regulation of macroautophagy#GO:0016239;cellular macromolecule localization#GO:0070727;regulation of cellular process#GO:0050794;protein transport#GO:0015031;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;positive regulation of catabolic process#GO:0009896;positive regulation of autophagy#GO:0010508;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;endosome#GO:0005768;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;SNARE complex#GO:0031201;early endosome#GO:0005769;organelle membrane#GO:0031090;cell periphery#GO:0071944;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endosome membrane#GO:0010008;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;early endosome membrane#GO:0031901;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cytoplasmic vesicle membrane#GO:0030659;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000023315.1|UniProtKB=H2XT38 H2XT38 PTHR24366:SF161 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS TIR DOMAIN-CONTAINING PROTEIN cell adhesion molecule#PC00069;immunoglobulin superfamily cell adhesion molecule#PC00125 CIOIN|Ensembl=ENSCING00000014093.2|UniProtKB=F6TDP5 F6TDP5 PTHR45710:SF26 C-TYPE LECTIN DOMAIN-CONTAINING PROTEIN 180 RH26557P defense/immunity protein#PC00090 CIOIN|Ensembl=ENSCING00000009141.3|UniProtKB=F7BBN1 F7BBN1 asak PTHR11055:SF1 BIFUNCTIONAL 3'-PHOSPHOADENOSINE 5'-PHOSPHOSULFATE SYNTHASE PAPS SYNTHETASE, ISOFORM D transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301 Sulfate assimilation#P02778>Sulfate adenylyltransferase#P03167;Sulfate assimilation#P02778>Adenylylsulfate kinase#P03164 CIOIN|Ensembl=ENSCING00000002782.3|UniProtKB=F6ZYD9 F6ZYD9 PTHR45632:SF27 LD33804P KELCH-LIKE PROTEIN 9 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000001882.3|UniProtKB=F6SIZ4 F6SIZ4 PTHR14453:SF67 PARP/ZINC FINGER CCCH TYPE DOMAIN CONTAINING PROTEIN POLY [ADP-RIBOSE] POLYMERASE molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714;protein-macromolecule adaptor activity#GO:0030674 negative regulation of gene expression#GO:0010629;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of biosynthetic process#GO:0009890;negative regulation of metabolic process#GO:0009892;regulation of biological process#GO:0050789;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000004712.3|UniProtKB=F6QMU4 F6QMU4 PTHR10352:SF25 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT G FOUND IN NEURONS, ISOFORM A-RELATED translation initiation factor#PC00224;translation factor#PC00223 CIOIN|Ensembl=ENSCING00000013109.2|UniProtKB=F7BNU5 F7BNU5 LOC101242566 PTHR12154:SF4 GLYCOSYL TRANSFERASE-RELATED UDP-N-ACETYLGLUCOSAMINE TRANSFERASE SUBUNIT ALG14 HOMOLOG acetylglucosaminyltransferase activity#GO:0008375;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;UDP-glycosyltransferase activity#GO:0008194 glycoprotein biosynthetic process#GO:0009101;organic hydroxy compound metabolic process#GO:1901615;macromolecule glycosylation#GO:0043413;lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;alcohol metabolic process#GO:0006066;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;isoprenoid metabolic process#GO:0006720;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein N-linked glycosylation#GO:0006487;cellular lipid metabolic process#GO:0044255;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;small molecule metabolic process#GO:0044281;glycosylation#GO:0070085;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000021764.1|UniProtKB=H2XX83 H2XX83 PTHR13313:SF0 CYTOCHROME C OXIDASE SUBUNIT VIIC CYTOCHROME C OXIDASE SUBUNIT 7C, MITOCHONDRIAL mitochondrial ATP synthesis coupled electron transport#GO:0042775;aerobic respiration#GO:0009060;cellular respiration#GO:0045333;respiratory electron transport chain#GO:0022904;generation of precursor metabolites and energy#GO:0006091;aerobic electron transport chain#GO:0019646;oxidative phosphorylation#GO:0006119;electron transport chain#GO:0022900;ATP synthesis coupled electron transport#GO:0042773;cellular metabolic process#GO:0044237;cellular process#GO:0009987;mitochondrial electron transport, cytochrome c to oxygen#GO:0006123;energy derivation by oxidation of organic compounds#GO:0015980;metabolic process#GO:0008152 oxidase#PC00175;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000005469.3|UniProtKB=F6U5W6 F6U5W6 PTHR48102:SF7 ATP-DEPENDENT CLP PROTEASE ATP-BINDING SUBUNIT CLPX-LIKE, MITOCHONDRIAL-RELATED ATP-DEPENDENT CLP PROTEASE ATP-BINDING SUBUNIT CLPX-LIKE, MITOCHONDRIAL carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;ATP hydrolysis activity#GO:0016887;pyrophosphatase activity#GO:0016462;ATP-dependent activity#GO:0140657;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;anion binding#GO:0043168;ion binding#GO:0043167;ATP binding#GO:0005524 macromolecule catabolic process#GO:0009057;nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;proteolysis#GO:0006508;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;catabolic process#GO:0009056;organonitrogen compound catabolic process#GO:1901565;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;primary metabolic process#GO:0044238 protease#PC00190;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000023682.1|UniProtKB=H2Y3I0 H2Y3I0 PTHR21064:SF1 AMINOGLYCOSIDE PHOSPHOTRANSFERASE DOMAIN-CONTAINING PROTEIN-RELATED HYDROXYLYSINE KINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301 CIOIN|Ensembl=ENSCING00000003467.3|UniProtKB=F6UAY9 F6UAY9 PTHR22935:SF95 PENICILLIN-BINDING PROTEIN BETA-LACTAMASE-LIKE 1-RELATED CIOIN|Ensembl=ENSCING00000009532.3|UniProtKB=F6UXC7 F6UXC7 PTHR14928:SF16 MICRO-RNA BINDING ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 7 C3H1-TYPE DOMAIN-CONTAINING PROTEIN nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;RNA metabolic process#GO:0016070;regulatory ncRNA processing#GO:0070918;RNA processing#GO:0006396;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulatory ncRNA-mediated gene silencing#GO:0031047;miRNA processing#GO:0035196;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000014393.2|UniProtKB=F6ZXR3 F6ZXR3 PTHR44942:SF4 METHYLTRANSF_11 DOMAIN-CONTAINING PROTEIN METHYLTRANSFERASE TYPE 11 DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000014266.2|UniProtKB=K9J6P7 K9J6P7 PTHR24412:SF497 KELCH PROTEIN KELCH-LIKE PROTEIN 18 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000020493.1|UniProtKB=H2Y0D6 H2Y0D6 PTHR11984:SF53 CONNEXIN GAP JUNCTION PROTEIN wide pore channel activity#GO:0022829;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;channel activity#GO:0015267 biological regulation#GO:0065007;regulation of biological process#GO:0050789;cell communication#GO:0007154;cellular process#GO:0009987;cell-cell signaling#GO:0007267;signaling#GO:0023052 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 cell junction protein#PC00070;gap junction#PC00105 CIOIN|Ensembl=ENSCING00000008300.3|UniProtKB=F6QC37 F6QC37 LOC100178987 PTHR19325:SF560 COMPLEMENT COMPONENT-RELATED SUSHI DOMAIN-CONTAINING SUSHI, VON WILLEBRAND FACTOR TYPE A, EGF AND PENTRAXIN DOMAIN-CONTAINING PROTEIN 1 complement component#PC00078 CIOIN|Ensembl=ENSCING00000023076.1|UniProtKB=H2XZG0 H2XZG0 PTHR24012:SF719 RNA BINDING PROTEIN RNA BINDING MOTIF PROTEIN 19 nucleic acid binding#GO:0003676;single-stranded RNA binding#GO:0003727;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159;mRNA binding#GO:0003729;poly(A) binding#GO:0008143;mRNA 3'-UTR binding#GO:0003730 supramolecular complex#GO:0099080;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic ribonucleoprotein granule#GO:0036464;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein complex#GO:1990904;ribonucleoprotein granule#GO:0035770;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;cytoplasmic stress granule#GO:0010494 RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000000844.3|UniProtKB=F6TBG7 F6TBG7 PTHR13886:SF4 JNK/SAPK-ASSOCIATED PROTEIN JNK-INTERACTING PROTEIN 3 kinesin binding#GO:0019894;cytoskeletal protein binding#GO:0008092;molecular adaptor activity#GO:0060090;signaling adaptor activity#GO:0035591;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;protein binding#GO:0005515;signaling receptor complex adaptor activity#GO:0030159 localization#GO:0051179;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization#GO:0051234;transport#GO:0006810 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000001669.3|UniProtKB=F6X8B5 F6X8B5 LOC100182084 PTHR10763:SF26 CELL DIVISION CONTROL PROTEIN 6-RELATED CELL DIVISION CONTROL PROTEIN 6 HOMOLOG DNA metabolism protein#PC00009;replication origin binding protein#PC00199 CIOIN|Ensembl=ENSCING00000000505.4|UniProtKB=F6VQ10 F6VQ10 PTHR45849:SF1 FACT COMPLEX SUBUNIT SSRP1 FACT COMPLEX SUBUNIT SSRP1 nucleosome binding#GO:0031491;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;chromatin binding#GO:0003682;histone binding#GO:0042393 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-DNA complex#GO:0032993;chromatin#GO:0000785;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;transcription elongation factor complex#GO:0008023;intracellular anatomical structure#GO:0005622;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 CIOIN|Ensembl=ENSCING00000011937.2|UniProtKB=E7FIY7 E7FIY7 nAChR PTHR18945:SF927 NEUROTRANSMITTER GATED ION CHANNEL ACETYLCHOLINE RECEPTOR SUBUNIT ALPHA-LIKE 1 transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;signaling receptor activity#GO:0038023;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;molecular transducer activity#GO:0060089;neurotransmitter receptor activity#GO:0030594;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267;monoatomic ion channel activity#GO:0005216;transporter activity#GO:0005215;ligand-gated channel activity#GO:0022834 transmembrane transport#GO:0055085;transport#GO:0006810;regulation of membrane potential#GO:0042391;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;localization#GO:0051179;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;synaptic signaling#GO:0099536;monoatomic ion transport#GO:0006811;signaling#GO:0023052;cell-cell signaling#GO:0007267 membrane protein complex#GO:0098796;synapse#GO:0045202;plasma membrane signaling receptor complex#GO:0098802;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;receptor complex#GO:0043235;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;neuron projection#GO:0043005;transmembrane transporter complex#GO:1902495;cell projection#GO:0042995;plasma membrane#GO:0005886 ligand-gated ion channel#PC00141;ion channel#PC00133;transporter#PC00227 Nicotinic acetylcholine receptor signaling pathway#P00044>alpha#P01088;Nicotinic acetylcholine receptor signaling pathway#P00044>nAChR#P01086 CIOIN|Ensembl=ENSCING00000005922.3|UniProtKB=F6ZHS2 F6ZHS2 PTHR43557:SF4 APOPTOSIS-INDUCING FACTOR 1 APOPTOSIS-INDUCING FACTOR 1, MITOCHONDRIAL nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;flavin adenine dinucleotide binding#GO:0050660;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;anion binding#GO:0043168;oxidoreductase activity, acting on NAD(P)H#GO:0016651;oxidoreductase activity#GO:0016491 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;mitochondrial respiratory chain complex assembly#GO:0033108;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;protein-containing complex assembly#GO:0065003;cell death#GO:0008219;programmed cell death#GO:0012501;cellular component organization#GO:0016043;mitochondrion organization#GO:0007005;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 oxidoreductase#PC00176 Apoptosis signaling pathway#P00006>AIF#P00286 CIOIN|Ensembl=ENSCING00000013272.2|UniProtKB=F6YMZ5 F6YMZ5 PTHR10769:SF3 40S RIBOSOMAL PROTEIN S28 SMALL RIBOSOMAL SUBUNIT PROTEIN ES28 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;RNA processing#GO:0006396;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;protein-RNA complex assembly#GO:0022618;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;ribosome biogenesis#GO:0042254;non-membrane-bounded organelle assembly#GO:0140694;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;organelle organization#GO:0006996;rRNA metabolic process#GO:0016072;protein-containing complex organization#GO:0043933;ribonucleoprotein complex biogenesis#GO:0022613;protein-RNA complex organization#GO:0071826;maturation of SSU-rRNA#GO:0030490;ribosomal small subunit biogenesis#GO:0042274 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic small ribosomal subunit#GO:0022627;cytosol#GO:0005829;small ribosomal subunit#GO:0015935;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000002461.3|UniProtKB=F6Q8G4 F6Q8G4 PTHR28583:SF1 ACID AMIDASE ACID CERAMIDASE hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;catalytic activity#GO:0003824 cysteine protease#PC00081;protease#PC00190 CIOIN|Ensembl=ENSCING00000007729.3|UniProtKB=F6ZID3 F6ZID3 PTHR10177:SF347 CYCLINS G2_MITOTIC-SPECIFIC CYCLIN-B3 protein kinase regulator activity#GO:0019887;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207 regulation of protein kinase activity#GO:0045859;regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;mitotic cell cycle phase transition#GO:0044772;regulation of nitrogen compound metabolic process#GO:0051171;cell cycle process#GO:0022402;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;cell cycle phase transition#GO:0044770;mitotic cell cycle process#GO:1903047;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;regulation of primary metabolic process#GO:0080090;mitotic cell cycle#GO:0000278;regulation of macromolecule metabolic process#GO:0060255;regulation of molecular function#GO:0065009;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;regulation of protein serine/threonine kinase activity#GO:0071900;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cyclin-dependent protein serine/threonine kinase activity#GO:0000079;regulation of kinase activity#GO:0043549;regulation of cellular metabolic process#GO:0031323 microtubule organizing center#GO:0005815;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;serine/threonine protein kinase complex#GO:1902554;protein kinase complex#GO:1902911;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856 kinase activator#PC00138 Cell cycle#P00013>Cyclin B#P00486;p53 pathway#P00059>Cyclin B#P04614 CIOIN|Ensembl=ENSCING00000015059.2|UniProtKB=F6S801 F6S801 PTHR24044:SF506 NOTCH LIGAND FAMILY MEMBER NEUROGENIC LOCUS NOTCH HOMOLOG PROTEIN 2-LIKE protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 intercellular signal molecule#PC00207 CIOIN|Ensembl=ENSCING00000020653.1|UniProtKB=H2XMC8 H2XMC8 PTHR24300:SF397 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 2U1 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;tetrapyrrole binding#GO:0046906;steroid hydroxylase activity#GO:0008395;oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497;heme binding#GO:0020037 response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;response to chemical#GO:0042221;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 oxygenase#PC00177;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000006188.3|UniProtKB=Q4H2T5 Q4H2T5 Ci-Smad2_3b PTHR13703:SF25 SMAD MOTHERS AGAINST DECAPENTAPLEGIC HOMOLOG cis-regulatory region sequence-specific DNA binding#GO:0000987;SMAD binding#GO:0046332;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;protein binding#GO:0005515;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nitrogen compound metabolic process#GO:0051171;response to growth factor#GO:0070848;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;cellular response to BMP stimulus#GO:0071773;cell differentiation#GO:0030154;positive regulation of biosynthetic process#GO:0009891;response to endogenous stimulus#GO:0009719;positive regulation of metabolic process#GO:0009893;anatomical structure morphogenesis#GO:0009653;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;response to BMP#GO:0071772;regulation of macromolecule biosynthetic process#GO:0010556;intracellular signal transduction#GO:0035556;intracellular signaling cassette#GO:0141124;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;signaling#GO:0023052;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;cellular response to endogenous stimulus#GO:0071495;regulation of DNA-templated transcription#GO:0006355;BMP signaling pathway#GO:0030509;cell communication#GO:0007154;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;activin receptor signaling pathway#GO:0032924;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular response to growth factor stimulus#GO:0071363;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;anatomical structure development#GO:0048856;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007;positive regulation of RNA metabolic process#GO:0051254;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218 MYO signaling pathway#P06215>SMOX#P06314;Activin beta signaling pathway#P06210>SMOX#P06236;ALP23B signaling pathway#P06209>SMOX#P06224;BMP/activin signaling pathway-drosophila#P06211>R-Smad#P06245;TGF-beta signaling pathway#P00052>RSmads#P01292 CIOIN|Ensembl=ENSCING00000020798.1|UniProtKB=H2XXB3 H2XXB3 PTHR46763:SF1 DYNEIN REGULATORY COMPLEX PROTEIN 8 DYNEIN REGULATORY COMPLEX PROTEIN 8 microtubule or microtubule-binding cytoskeletal protein#PC00157 CIOIN|Ensembl=ENSCING00000009386.3|UniProtKB=F6WBE1 F6WBE1 LOC100180646 PTHR11130:SF0 GLUTATHIONE SYNTHETASE GLUTATHIONE SYNTHETASE ligase activity#GO:0016874;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;amide binding#GO:0033218;peptide binding#GO:0042277;ion binding#GO:0043167;anion binding#GO:0043168 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ligase#PC00142;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000008979.3|UniProtKB=F6PKL1 F6PKL1 LOC100182844 PTHR23316:SF71 IMPORTIN ALPHA IMPORTIN SUBUNIT ALPHA signal sequence binding#GO:0005048;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277 cellular localization#GO:0051641;NLS-bearing protein import into nucleus#GO:0006607;macromolecule localization#GO:0033036;transport#GO:0006810;protein localization to nucleus#GO:0034504;nitrogen compound transport#GO:0071705;establishment of protein localization to organelle#GO:0072594;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;protein import into nucleus#GO:0006606;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;protein localization to organelle#GO:0033365;nuclear transport#GO:0051169;import into nucleus#GO:0051170 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transporter#PC00227 CIOIN|Ensembl=ENSCING00000003319.3|UniProtKB=Q1RPZ2 Q1RPZ2 Ci-ZF(MATRIN)-2 PTHR23205:SF0 SPLICING FACTOR 3A SUBUNIT 2 SPLICING FACTOR 3A SUBUNIT 2 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;RNA processing#GO:0006396;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;protein-RNA complex assembly#GO:0022618;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;mRNA splicing, via spliceosome#GO:0000398;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;protein-containing complex organization#GO:0043933;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;ribonucleoprotein complex biogenesis#GO:0022613;mRNA processing#GO:0006397;protein-RNA complex organization#GO:0071826;RNA splicing, via transesterification reactions#GO:0000375;spliceosomal complex assembly#GO:0000245 catalytic step 2 spliceosome#GO:0071013;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;U2-type spliceosomal complex#GO:0005684;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;spliceosomal snRNP complex#GO:0097525;small nuclear ribonucleoprotein complex#GO:0030532;protein-containing complex#GO:0032991;U2 snRNP#GO:0005686;U2-type prespliceosome#GO:0071004;membrane-bounded organelle#GO:0043227;Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513 RNA splicing factor#PC00148;RNA processing factor#PC00147;RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000024830.1|UniProtKB=H2XQ34 H2XQ34 PTHR13768:SF8 SOLUBLE NSF ATTACHMENT PROTEIN SNAP ALPHA-SOLUBLE NSF ATTACHMENT PROTEIN syntaxin binding#GO:0019905;molecular adaptor activity#GO:0060090;protein binding#GO:0005515;binding#GO:0005488;SNARE binding#GO:0000149;protein-macromolecule adaptor activity#GO:0030674 cellular localization#GO:0051641;protein-containing complex disassembly#GO:0032984;macromolecule localization#GO:0033036;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;cellular component disassembly#GO:0022411;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein-containing complex organization#GO:0043933;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 bounding membrane of organelle#GO:0098588;cytoplasm#GO:0005737;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;vacuolar membrane#GO:0005774;SNARE complex#GO:0031201;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150 CIOIN|Ensembl=ENSCING00000024130.1|UniProtKB=H2XNB1 H2XNB1 PTHR22960:SF0 MOLYBDOPTERIN COFACTOR SYNTHESIS PROTEIN A MOLYBDENUM COFACTOR BIOSYNTHESIS PROTEIN 1 lyase activity#GO:0016829;carbon-carbon lyase activity#GO:0016830;phosphorus-oxygen lyase activity#GO:0016849;catalytic activity#GO:0003824 heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;organophosphate biosynthetic process#GO:0090407;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;organophosphate metabolic process#GO:0019637;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 CIOIN|Ensembl=ENSCING00000015366.2|UniProtKB=F7A5R9 F7A5R9 PTHR32179:SF3 NICOTINATE-NUCLEOTIDE PYROPHOSPHORYLASE [CARBOXYLATING] NICOTINATE-NUCLEOTIDE PYROPHOSPHORYLASE [CARBOXYLATING] transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;pentosyltransferase activity#GO:0016763;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;dicarboxylic acid metabolic process#GO:0043648;heterocycle catabolic process#GO:0046700;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;organonitrogen compound catabolic process#GO:1901565;purine-containing compound biosynthetic process#GO:0072522;pyridine nucleotide metabolic process#GO:0019362;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;cellular nitrogen compound catabolic process#GO:0044270;phosphate-containing compound metabolic process#GO:0006796;nucleotide biosynthetic process#GO:0009165;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;pyridine-containing compound metabolic process#GO:0072524;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;purine nucleotide metabolic process#GO:0006163;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;nicotinamide nucleotide metabolic process#GO:0046496;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;nucleobase-containing compound biosynthetic process#GO:0034654;small molecule catabolic process#GO:0044282;organic cyclic compound catabolic process#GO:1901361;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;carboxylic acid metabolic process#GO:0019752;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000007804.3|UniProtKB=F6WHS8 F6WHS8 PTHR13831:SF0 MEMBER OF THE HIR1 FAMILY OF WD-REPEAT PROTEINS PROTEIN HIRA nucleosome binding#GO:0031491;protein-containing complex binding#GO:0044877;binding#GO:0005488;chromatin binding#GO:0003682 cellular component organization or biogenesis#GO:0071840;chromatin organization#GO:0006325;protein-DNA complex organization#GO:0071824;cellular component organization#GO:0016043;cellular process#GO:0009987;chromatin remodeling#GO:0006338;protein-containing complex organization#GO:0043933 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;protein-DNA complex#GO:0032993;chromosome#GO:0005694;chromatin#GO:0000785;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 CIOIN|Ensembl=ENSCING00000014982.2|UniProtKB=F6UVK0 F6UVK0 PTHR13289:SF6 PROTEIN PHOSPHATASE 1-BINDING PROTEIN BIFOCAL MACOILIN cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 regulation of biological process#GO:0050789;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;locomotion#GO:0040011;signaling#GO:0023052;chemotaxis#GO:0006935;taxis#GO:0042330 envelope#GO:0031975;bounding membrane of organelle#GO:0098588;rough endoplasmic reticulum membrane#GO:0030867;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;nuclear membrane#GO:0031965;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;rough endoplasmic reticulum#GO:0005791;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 transporter#PC00227 CIOIN|Ensembl=ENSCING00000009136.3|UniProtKB=F6S2A1 F6S2A1 PTHR44394:SF1 BETA-ALANINE-ACTIVATING ENZYME BETA-ALANINE-ACTIVATING ENZYME ligase#PC00142 CIOIN|Ensembl=ENSCING00000014313.2|UniProtKB=F6UMV2 F6UMV2 LOC104266013 PTHR16165:SF5 NXPE FAMILY MEMBER NXPE FAMILY MEMBER 3 CIOIN|Ensembl=ENSCING00000007207.3|UniProtKB=F6Y7P7 F6Y7P7 LOC100176643 PTHR21257:SF38 DELTA(14)-STEROL REDUCTASE 7-DEHYDROCHOLESTEROL REDUCTASE oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor#GO:0016628 sterol metabolic process#GO:0016125;organic hydroxy compound metabolic process#GO:1901615;lipid metabolic process#GO:0006629;organic hydroxy compound biosynthetic process#GO:1901617;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;regulation of hormone levels#GO:0010817;lipid biosynthetic process#GO:0008610;primary metabolic process#GO:0044238;hormone metabolic process#GO:0042445;steroid metabolic process#GO:0008202;organic cyclic compound metabolic process#GO:1901360;phytosteroid metabolic process#GO:0016128;regulation of biological quality#GO:0065008;biological regulation#GO:0065007;steroid biosynthetic process#GO:0006694;metabolic process#GO:0008152;sterol biosynthetic process#GO:0016126;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 reductase#PC00198;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000009605.3|UniProtKB=F7ADR7 F7ADR7 LOC100180056 PTHR48083:SF20 MEDIUM-CHAIN SPECIFIC ACYL-COA DEHYDROGENASE, MITOCHONDRIAL-RELATED LONG-CHAIN SPECIFIC ACYL-COA DEHYDROGENASE, MITOCHONDRIAL nucleotide binding#GO:0000166;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;flavin adenine dinucleotide binding#GO:0050660;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167;oxidoreductase activity#GO:0016491 oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;lipid oxidation#GO:0034440;cellular metabolic process#GO:0044237;lipid catabolic process#GO:0016042;lipid modification#GO:0030258;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;fatty acid catabolic process#GO:0009062;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;fatty acid metabolic process#GO:0006631;small molecule catabolic process#GO:0044282;fatty acid beta-oxidation#GO:0006635;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;cellular lipid metabolic process#GO:0044255;cellular lipid catabolic process#GO:0044242;carboxylic acid metabolic process#GO:0019752;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;monocarboxylic acid catabolic process#GO:0072329 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 dehydrogenase#PC00092;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000005230.3|UniProtKB=F6YHC8 F6YHC8 PTHR10137:SF0 V-TYPE PROTON ATPASE SUBUNIT C V-TYPE PROTON ATPASE SUBUNIT C inorganic molecular entity transmembrane transporter activity#GO:0015318;transmembrane transporter activity#GO:0022857;primary active transmembrane transporter activity#GO:0015399;ATP-dependent activity#GO:0140657;proton transmembrane transporter activity#GO:0015078;active monoatomic ion transmembrane transporter activity#GO:0022853;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;ATPase-coupled transmembrane transporter activity#GO:0042626;monoatomic cation transmembrane transporter activity#GO:0008324;monoatomic ion transmembrane transporter activity#GO:0015075;inorganic cation transmembrane transporter activity#GO:0022890;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;vacuolar membrane#GO:0005774;ATPase complex#GO:1904949;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;proton-transporting two-sector ATPase complex#GO:0016469;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227 ATP synthase#PC00002;primary active transporter#PC00068;transporter#PC00227 CIOIN|Ensembl=ENSCING00000007972.3|UniProtKB=F6WRR9 F6WRR9 PTHR18957:SF0 CENTLEIN CENTLEIN cellular localization#GO:0051641;macromolecule localization#GO:0033036;cell cycle process#GO:0022402;centrosome cycle#GO:0007098;microtubule cytoskeleton organization#GO:0000226;cellular component organization#GO:0016043;cellular process#GO:0009987;microtubule organizing center organization#GO:0031023;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;microtubule-based process#GO:0007017;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;cell cycle#GO:0007049;protein localization to organelle#GO:0033365 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;centriole#GO:0005814;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000006680.3|UniProtKB=F7BAL4 F7BAL4 LOC108949460 PTHR23330:SF9 P300 TRANSCRIPTIONAL COFACTOR JMY-RELATED PROLINE-RICH PROTEIN 11 CIOIN|Ensembl=ENSCING00000012483.2|UniProtKB=F6U5S2 F6U5S2 PTHR11208:SF45 RNA-BINDING PROTEIN RELATED SPLICING FACTOR 1 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 regulation of nitrogen compound metabolic process#GO:0051171;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of RNA splicing#GO:0043484;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of mRNA processing#GO:0050684;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;regulation of mRNA metabolic process#GO:1903311 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA splicing factor#PC00148;RNA processing factor#PC00147;RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000009638.3|UniProtKB=A0A1W5B570 A0A1W5B570 LOC104265690 PTHR12271:SF66 POLY A POLYMERASE CID PAP -RELATED TERMINAL URIDYLYLTRANSFERASE TAILOR catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on RNA#GO:0140098;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;RNA 3'-end processing#GO:0031123;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 nucleotidyltransferase#PC00174 CIOIN|Ensembl=ENSCING00000010806.3|UniProtKB=F6WY52 F6WY52 PTHR19134:SF527 RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 7 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;protein tyrosine phosphatase activity#GO:0004725;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 protein phosphatase#PC00195;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000008849.3|UniProtKB=F6R407 F6R407 PTHR13213:SF2 MYB-BINDING PROTEIN 1A FAMILY MEMBER MYB-BINDING PROTEIN 1A intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 CIOIN|Ensembl=ENSCING00000016626.2|UniProtKB=F6U351 F6U351 PTHR10454:SF31 CASPASE CASPASE-7 cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197;hydrolase activity#GO:0016787;cysteine-type endopeptidase activity involved in apoptotic process#GO:0097153;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 regulation of biological process#GO:0050789;positive regulation of apoptotic process#GO:0043065;positive regulation of programmed cell death#GO:0043068;regulation of apoptotic process#GO:0042981;regulation of cellular process#GO:0050794;apoptotic process#GO:0006915;biological regulation#GO:0065007;cell death#GO:0008219;programmed cell death#GO:0012501;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;regulation of programmed cell death#GO:0043067;positive regulation of cellular process#GO:0048522 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 protease#PC00190;protein modifying enzyme#PC00260 FAS signaling pathway#P00020>Caspase7#P00595;Apoptosis signaling pathway#P00006>Caspase 7#P00300;FAS signaling pathway#P00020>Pro-Caspase7#P00605 CIOIN|Ensembl=ENSCING00000002430.3|UniProtKB=F6QH36 F6QH36 PTHR10048:SF15 PHOSPHATIDYLINOSITOL KINASE PHOSPHATIDYLINOSITOL 4-KINASE ALPHA transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301;lipid kinase activity#GO:0001727 lipid metabolic process#GO:0006629;signal transduction#GO:0007165;phospholipid biosynthetic process#GO:0008654;organophosphate biosynthetic process#GO:0090407;phosphatidylinositol biosynthetic process#GO:0006661;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;lipid biosynthetic process#GO:0008610;phosphatidylinositol phosphate biosynthetic process#GO:0046854;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;glycerolipid metabolic process#GO:0046486;intracellular signal transduction#GO:0035556;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;glycerolipid biosynthetic process#GO:0045017;cellular metabolic process#GO:0044237;cell communication#GO:0007154;glycerophospholipid metabolic process#GO:0006650;phosphatidylinositol metabolic process#GO:0046488;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;glycerophospholipid biosynthetic process#GO:0046474;biological regulation#GO:0065007;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 kinase#PC00137 CIOIN|Ensembl=ENSCING00000016550.2|UniProtKB=F6X153 F6X153 PTHR46583:SF1 REGULATOR OF G-PROTEIN SIGNALING 22 REGULATOR OF G-PROTEIN SIGNALING 22 protein binding#GO:0005515;binding#GO:0005488 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000022694.1|UniProtKB=H2XLI5 H2XLI5 PTHR45619:SF10 SERINE/THREONINE-PROTEIN PHOSPHATASE PP2A-RELATED SERINE_THREONINE-PROTEIN PHOSPHATASE 6 CATALYTIC SUBUNIT hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;protein serine/threonine phosphatase activity#GO:0004722;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 protein phosphatase#PC00195;protein modifying enzyme#PC00260 EGF receptor signaling pathway#P00018>PP2A#P00547;FGF signaling pathway#P00021>PP2A#P00629 CIOIN|Ensembl=ENSCING00000006854.3|UniProtKB=F6ZX12 F6ZX12 LOC100181830 PTHR11921:SF29 SUCCINATE DEHYDROGENASE IRON-SULFUR PROTEIN SUCCINATE DEHYDROGENASE [UBIQUINONE] IRON-SULFUR SUBUNIT, MITOCHONDRIAL cellular respiration#GO:0045333;aerobic respiration#GO:0009060;respiratory electron transport chain#GO:0022904;generation of precursor metabolites and energy#GO:0006091;cellular metabolic process#GO:0044237;electron transport chain#GO:0022900;cellular process#GO:0009987;energy derivation by oxidation of organic compounds#GO:0015980;metabolic process#GO:0008152 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000004137.3|UniProtKB=H2XRD9 H2XRD9 PTHR22957:SF645 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN LD27216P nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 regulation of molecular function#GO:0065009;regulation of GTPase activity#GO:0043087;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;activation of GTPase activity#GO:0090630;biological regulation#GO:0065007;positive regulation of molecular function#GO:0044093;regulation of hydrolase activity#GO:0051336;regulation of catalytic activity#GO:0050790;positive regulation of hydrolase activity#GO:0051345 GTPase-activating protein#PC00257 CIOIN|Ensembl=ENSCING00000020211.1|UniProtKB=H2XXH1 H2XXH1 LOC100186308 PTHR21569:SF16 RIBOSOMAL PROTEIN S9 RIBOSOMAL PROTEIN S16 structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;structural molecule activity#GO:0005198;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;maturation of SSU-rRNA#GO:0030490;ribosomal small subunit biogenesis#GO:0042274;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic small ribosomal subunit#GO:0022627;cytosol#GO:0005829;small ribosomal subunit#GO:0015935;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000019689.1|UniProtKB=H2XPD0 H2XPD0 LOC100181207 PTHR11908:SF132 XANTHINE DEHYDROGENASE ALDEHYDE OXIDASE 1-RELATED oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 oxidoreductase#PC00176 Adenine and hypoxanthine salvage pathway#P02723>Xanthine dehydrogenase#P02809;Purine metabolism#P02769>Xanthine Oxidase#P03116 CIOIN|Ensembl=ENSCING00000007375.3|UniProtKB=A0A1W2WNG5 A0A1W2WNG5 LOC100176319 PTHR23147:SF76 SERINE/ARGININE RICH SPLICING FACTOR LD40489P nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;nuclear speck#GO:0016607;organelle#GO:0043226;nuclear body#GO:0016604;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA splicing factor#PC00148;RNA processing factor#PC00147;RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000006499.3|UniProtKB=F6Q0X6 F6Q0X6 PTHR16083:SF85 LEUCINE RICH REPEAT CONTAINING PROTEIN FI16115P1 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000013819.2|UniProtKB=F6Y0G1 F6Y0G1 LOC100178052 PTHR13924:SF10 TRANSFORMING ACIDIC COILED-COIL CONTAINING PROTEIN 1/2 TRANSFORMING ACIDIC COILED-COIL PROTEIN, ISOFORM K CIOIN|Ensembl=ENSCING00000006296.3|UniProtKB=F6UCD8 F6UCD8 PTHR13780:SF35 AMP-ACTIVATED PROTEIN KINASE, GAMMA REGULATORY SUBUNIT LD22662P kinase modulator#PC00140 CIOIN|Ensembl=ENSCING00000014331.1|UniProtKB=F6TZK8 F6TZK8 LOC100175299 PTHR13966:SF5 ENDONUCLEASE RELATED ENDONUCLEASE G, MITOCHONDRIAL endonuclease activity#GO:0004519;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;catalytic activity#GO:0003824 Apoptosis signaling pathway#P00006>endoG#P00279 CIOIN|Ensembl=ENSCING00000023496.1|UniProtKB=F6ZUI8 F6ZUI8 PTHR11559:SF424 CARBOXYLESTERASE CARBOXYLESTERASE 1D-LIKE ISOFORM X1 esterase#PC00097;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000014168.2|UniProtKB=F6XEB9 F6XEB9 PTHR10454:SF31 CASPASE CASPASE-7 cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197;hydrolase activity#GO:0016787;cysteine-type endopeptidase activity involved in apoptotic process#GO:0097153;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 regulation of biological process#GO:0050789;positive regulation of apoptotic process#GO:0043065;positive regulation of programmed cell death#GO:0043068;regulation of apoptotic process#GO:0042981;regulation of cellular process#GO:0050794;apoptotic process#GO:0006915;biological regulation#GO:0065007;cell death#GO:0008219;programmed cell death#GO:0012501;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;regulation of programmed cell death#GO:0043067;positive regulation of cellular process#GO:0048522 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 protease#PC00190;protein modifying enzyme#PC00260 FAS signaling pathway#P00020>Caspase7#P00595;Apoptosis signaling pathway#P00006>Caspase 7#P00300;FAS signaling pathway#P00020>Pro-Caspase7#P00605 CIOIN|Ensembl=ENSCING00000005271.3|UniProtKB=F6V8T1 F6V8T1 PTHR32003:SF1 PROTEIN FAM199X PROTEIN FAM199X CIOIN|Ensembl=ENSCING00000012370.2|UniProtKB=F6X9C7 F6X9C7 LOC100185978 PTHR23003:SF51 RNA RECOGNITION MOTIF RRM DOMAIN CONTAINING PROTEIN SERINE-ARGININE PROTEIN 55 nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA splicing factor#PC00148;RNA processing factor#PC00147;RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000002632.3|UniProtKB=F7AJ84 F7AJ84 PTHR22762:SF54 ALPHA-GLUCOSIDASE BCDNA.GH04962 hydrolase activity#GO:0016787;glucosidase activity#GO:0015926;hydrolase activity, acting on glycosyl bonds#GO:0016798;alpha-glucosidase activity#GO:0090599;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 carbohydrate derivative metabolic process#GO:1901135;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 glucosidase#PC00108;metabolite interconversion enzyme#PC00262;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000000941.3|UniProtKB=F7BB18 F7BB18 PTHR11929:SF145 ALPHA- 1,3 -FUCOSYLTRANSFERASE ALPHA-(1,3)-FUCOSYLTRANSFERASE FUT-1 transferase activity#GO:0016740;fucosyltransferase activity#GO:0008417;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 glycosylation#GO:0070085;metabolic process#GO:0008152 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000009761.3|UniProtKB=F6ZTL3 F6ZTL3 PTHR42985:SF45 SODIUM-COUPLED MONOCARBOXYLATE TRANSPORTER SODIUM_IODIDE COTRANSPORTER-LIKE symporter activity#GO:0015293;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 localization#GO:0051179;monoatomic cation transport#GO:0006812;sodium ion transport#GO:0006814;metal ion transport#GO:0030001;establishment of localization#GO:0051234;monoatomic ion transport#GO:0006811;transport#GO:0006810 secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000018927.1|UniProtKB=H2Y0M5 H2Y0M5 PTHR46780:SF9 PROTEIN EVA-1 D-GALACTOSIDE_L-RHAMNOSE BINDING SUEL LECTIN PROTEIN CIOIN|Ensembl=ENSCING00000004387.3|UniProtKB=A0A1W5BJW2 A0A1W5BJW2 LOC100187321 PTHR20383:SF9 RNA POLYMERASE II SUBUNIT A C-TERMINAL DOMAIN PHOSPHATASE RNA POLYMERASE II SUBUNIT A C-TERMINAL DOMAIN PHOSPHATASE SSU72 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;protein serine/threonine phosphatase activity#GO:0004722;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 cellular aromatic compound metabolic process#GO:0006725;DNA-templated transcription#GO:0006351;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;RNA biosynthetic process#GO:0032774;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;aromatic compound biosynthetic process#GO:0019438;transcription by RNA polymerase II#GO:0006366;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;mRNA cleavage factor complex#GO:0005849;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;mRNA cleavage and polyadenylation specificity factor complex#GO:0005847;intracellular anatomical structure#GO:0005622 protein phosphatase#PC00195;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000013830.2|UniProtKB=F6QLF3 F6QLF3 LOC100180334 PTHR12289:SF67 METAXIN RELATED SUBFAMILY NOT NAMED cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 transporter#PC00227 CIOIN|Ensembl=ENSCING00000007142.3|UniProtKB=F7BH23 F7BH23 LOC100185622 PTHR46212:SF9 PEFLIN PROGRAMMED CELL DEATH PROTEIN 6 CIOIN|Ensembl=ENSCING00000000695.3|UniProtKB=F6QRE5 F6QRE5 LOC104266818 PTHR13869:SF24 MYELIN P0 RELATED BASEMENT MEMBRANE-SPECIFIC HEPARAN SULFATE PROTEOGLYCAN CORE PROTEIN-LIKE myelin protein#PC00161;structural protein#PC00211 CIOIN|Ensembl=ENSCING00000007736.3|UniProtKB=F6Z0B9 F6Z0B9 PTHR32022:SF10 D-GLUTAMATE CYCLASE, MITOCHONDRIAL D-GLUTAMATE CYCLASE, MITOCHONDRIAL cyclase#PC00079;lyase#PC00144 CIOIN|Ensembl=ENSCING00000014153.1|UniProtKB=F7ARA1 F7ARA1 LOC100181578 PTHR10845:SF259 REGULATOR OF G PROTEIN SIGNALING RGS DOMAIN-CONTAINING PROTEIN-RELATED G-protein modulator#PC00022;protein-binding activity modulator#PC00095;GTPase-activating protein#PC00257 CIOIN|Ensembl=ENSCING00000022498.1|UniProtKB=H2XPJ3 H2XPJ3 PTHR12356:SF18 NUCLEAR MOVEMENT PROTEIN NUDC NUDC DOMAIN-CONTAINING PROTEIN 2 protein binding#GO:0005515;unfolded protein binding#GO:0051082;binding#GO:0005488 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein folding#GO:0006457;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;microtubule or microtubule-binding cytoskeletal protein#PC00157 CIOIN|Ensembl=ENSCING00000004221.3|UniProtKB=F6ZXH6 F6ZXH6 PTHR12663:SF0 ANDROGEN INDUCED INHIBITOR OF PROLIFERATION AS3 / PDS5-RELATED PRECOCIOUS DISSOCIATION OF SISTERS 5, ISOFORM A DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;mitotic sister chromatid cohesion#GO:0007064;macromolecule metabolic process#GO:0043170;cell cycle process#GO:0022402;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;sister chromatid cohesion#GO:0007062;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;DNA damage response#GO:0006974;response to stress#GO:0006950;organic cyclic compound metabolic process#GO:1901360;organelle organization#GO:0006996;chromosome organization#GO:0051276;nitrogen compound metabolic process#GO:0006807;cell cycle#GO:0007049;cellular response to stress#GO:0033554;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 CIOIN|Ensembl=ENSCING00000024378.1|UniProtKB=H2XUB9 H2XUB9 PTHR24070:SF448 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY SCA1 COMPLEX PROTEIN PHR GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;ion binding#GO:0043167;anion binding#GO:0043168 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 small GTPase#PC00208;G-protein#PC00020 EGF receptor signaling pathway#P00018>Ras#P00552 CIOIN|Ensembl=ENSCING00000006516.3|UniProtKB=F6PV66 F6PV66 PTHR12156:SF5 PLECKSTRIN HOMOLOGY-LIKE DOMAIN, FAMILY B, MEMBER 3 FI18040P1 CIOIN|Ensembl=ENSCING00000014004.2|UniProtKB=Q0E670 Q0E670 cmas PTHR21485:SF3 HAD SUPERFAMILY MEMBERS CMAS AND KDSC N-ACYLNEURAMINATE CYTIDYLYLTRANSFERASE transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779 nucleotidyltransferase#PC00174 CIOIN|Ensembl=ENSCING00000020702.1|UniProtKB=H2XTA3 H2XTA3 PTHR24034:SF209 EGF-LIKE DOMAIN-CONTAINING PROTEIN EGF-LIKE DOMAIN-CONTAINING PROTEIN extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 CIOIN|Ensembl=ENSCING00000012157.2|UniProtKB=F6UHX2 F6UHX2 PTHR10201:SF331 MATRIX METALLOPROTEINASE MATRIX METALLOPROTEINASE-14-LIKE ISOFORM X1 hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular component organization or biogenesis#GO:0071840;extracellular structure organization#GO:0043062;external encapsulating structure organization#GO:0045229;catabolic process#GO:0009056;cellular component organization#GO:0016043;cellular process#GO:0009987;extracellular matrix organization#GO:0030198;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000009039.3|UniProtKB=F6R763 F6R763 PTHR12631:SF8 ALPHA-L-IDURONIDASE ALPHA-L-IDURONIDASE hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 glycosidase#PC00110;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000003798.3|UniProtKB=F7AC90 F7AC90 LOC100177500 PTHR35836:SF1 VCBS REPEAT-CONTAINING PROTEIN VCBS REPEAT-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000001123.3|UniProtKB=F6ZDD5 F6ZDD5 PTHR11388:SF160 ORGANIC ANION TRANSPORTER SOLUTE CARRIER ORGANIC ANION TRANSPORTER FAMILY MEMBER secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 localization#GO:0051179;organic substance transport#GO:0071702;establishment of localization#GO:0051234;organic anion transport#GO:0015711;transport#GO:0006810 basal plasma membrane#GO:0009925;basolateral plasma membrane#GO:0016323;plasma membrane region#GO:0098590;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;basal part of cell#GO:0045178;plasma membrane#GO:0005886 transporter#PC00227 CIOIN|Ensembl=ENSCING00000020821.1|UniProtKB=H2Y3J5 H2Y3J5 PTHR44942:SF4 METHYLTRANSF_11 DOMAIN-CONTAINING PROTEIN METHYLTRANSFERASE TYPE 11 DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000008895.3|UniProtKB=F6QF37 F6QF37 PTHR11846:SF0 ADENYLOSUCCINATE SYNTHETASE ADENYLOSUCCINATE SYNTHETASE ligase activity#GO:0016874;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;purine ribonucleoside monophosphate metabolic process#GO:0009167;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;nucleotide biosynthetic process#GO:0009165;nucleoside monophosphate metabolic process#GO:0009123;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;IMP metabolic process#GO:0046040;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;purine nucleoside monophosphate metabolic process#GO:0009126;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;ribonucleoside monophosphate metabolic process#GO:0009161;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ligase#PC00142;metabolite interconversion enzyme#PC00262 Wnt signaling pathway#P00057>NFAT Target Genes#G01559;De novo purine biosynthesis#P02738>Adenylosuccinate synthase#P02890 CIOIN|Ensembl=ENSCING00000008256.3|UniProtKB=Q8I7E2 Q8I7E2 erd2 PTHR10585:SF14 ER LUMEN PROTEIN RETAINING RECEPTOR ER LUMEN PROTEIN-RETAINING RECEPTOR signal sequence binding#GO:0005048;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277 endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;protein localization to endoplasmic reticulum#GO:0070972;macromolecule localization#GO:0033036;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;protein localization#GO:0008104;localization#GO:0051179;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;maintenance of location#GO:0051235;maintenance of location in cell#GO:0051651;establishment of localization in cell#GO:0051649;protein localization to organelle#GO:0033365;intracellular transport#GO:0046907 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cis-Golgi network#GO:0005801;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 membrane trafficking regulatory protein#PC00151 CIOIN|Ensembl=ENSCING00000009046.3|UniProtKB=F6XFV3 F6XFV3 PTHR13140:SF858 MYOSIN MYOSIN MOTOR DOMAIN-CONTAINING PROTEIN microfilament motor activity#GO:0000146;cytoskeletal protein binding#GO:0008092;ATP-dependent activity#GO:0140657;binding#GO:0005488;actin filament binding#GO:0051015;cytoskeletal motor activity#GO:0003774;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779 cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;membrane#GO:0016020;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 actin binding motor protein#PC00040 CIOIN|Ensembl=ENSCING00000001639.3|UniProtKB=F7APJ4 F7APJ4 tr2_4 PTHR24083:SF54 NUCLEAR HORMONE RECEPTOR NUCLEAR HORMONE RECEPTOR HR78 cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;signaling receptor activity#GO:0038023;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular transducer activity#GO:0060089;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 C4 zinc finger nuclear receptor#PC00169;zinc finger transcription factor#PC00244 CIOIN|Ensembl=ENSCING00000002962.3|UniProtKB=F6U095 F6U095 PTHR12841:SF6 PROTEIN UNC-50 HOMOLOG PROTEIN UNC-50 HOMOLOG cytoplasm#GO:0005737;bounding membrane of organelle#GO:0098588;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;Golgi membrane#GO:0000139;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000003619.3|UniProtKB=A0A1W5B8N9 A0A1W5B8N9 LOC100175192 PTHR11732:SF506 ALDO/KETO REDUCTASE ALDO-KETO REDUCTASE 1B, ISOFORM C-RELATED oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 reductase#PC00198;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000007338.3|UniProtKB=F6XZ80 F6XZ80 LOC100183513 PTHR36978:SF4 P-LOOP CONTAINING NUCLEOTIDE TRIPHOSPHATE HYDROLASE P-LOOP CONTAINING NUCLEOSIDE TRIPHOSPHATE HYDROLASE PROTEIN metabolite interconversion enzyme#PC00262;hydrolase#PC00121 CIOIN|Ensembl=ENSCING00000013233.2|UniProtKB=F6V476 F6V476 PTHR46485:SF5 LIM DOMAIN KINASE 1 CENTER DIVIDER, ISOFORM A CIOIN|Ensembl=ENSCING00000012881.2|UniProtKB=F6PUA9 F6PUA9 PTHR14074:SF16 HELICASE WITH DEATH DOMAIN-RELATED ANTIVIRAL INNATE IMMUNE RESPONSE RECEPTOR RIG-I cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000004732.3|UniProtKB=F6PWR0 F6PWR0 LOC100180468 PTHR13168:SF0 ASSOCIATE OF C-MYC AMY-1 C-MYC-BINDING PROTEIN transcription coactivator activity#GO:0003713;molecular adaptor activity#GO:0060090;transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;protein-macromolecule adaptor activity#GO:0030674 regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transcription cofactor#PC00217 PDGF signaling pathway#P00047>c-Myc#P01172 CIOIN|Ensembl=ENSCING00000005403.3|UniProtKB=F6Z916 F6Z916 PTHR18945:SF930 NEUROTRANSMITTER GATED ION CHANNEL GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT BETA-3-LIKE signaling receptor activity#GO:0038023;inorganic molecular entity transmembrane transporter activity#GO:0015318;chloride channel activity#GO:0005254;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;molecular transducer activity#GO:0060089;chloride transmembrane transporter activity#GO:0015108;monoatomic anion transmembrane transporter activity#GO:0008509;inorganic anion transmembrane transporter activity#GO:0015103;monoatomic ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267;monoatomic ion channel activity#GO:0005216;transporter activity#GO:0005215;transmembrane signaling receptor activity#GO:0004888 localization#GO:0051179;inorganic anion transmembrane transport#GO:0098661;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic anion transmembrane transport#GO:0098656;monoatomic ion transmembrane transport#GO:0034220;transport#GO:0006810;monoatomic anion transport#GO:0006820;chloride transport#GO:0006821;chloride transmembrane transport#GO:1902476;inorganic ion transmembrane transport#GO:0098660;monoatomic ion transport#GO:0006811;cellular process#GO:0009987;inorganic anion transport#GO:0015698 receptor complex#GO:0043235;protein-containing complex#GO:0032991 ligand-gated ion channel#PC00141;ion channel#PC00133;transporter#PC00227 CIOIN|Ensembl=ENSCING00000004765.3|UniProtKB=F6PMB4 F6PMB4 LOC100181542 PTHR11736:SF14 MELANOMA-ASSOCIATED ANTIGEN MAGE ANTIGEN NSE3 HOMOLOG, SMC5-SMC6 COMPLEX COMPONENT membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000022553.1|UniProtKB=H2XS53 H2XS53 LOC100179278 PTHR43675:SF8 ARSENITE METHYLTRANSFERASE ARSENITE METHYLTRANSFERASE methyltransferase activity#GO:0008168;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824 methyltransferase#PC00155;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000004340.3|UniProtKB=F7BMR9 F7BMR9 LOC100178161 PTHR12944:SF2 SOLUBLE LIVER ANTIGEN/LIVER PANCREAS ANTIGEN O-PHOSPHOSERYL-TRNA(SEC) SELENIUM TRANSFERASE tRNA binding#GO:0000049;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 regulation of protein metabolic process#GO:0051246;regulation of amide metabolic process#GO:0034248;regulation of nitrogen compound metabolic process#GO:0051171;peptide metabolic process#GO:0006518;gene expression#GO:0010467;biosynthetic process#GO:0009058;translation#GO:0006412;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;regulation of primary metabolic process#GO:0080090;peptide biosynthetic process#GO:0043043;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;post-transcriptional regulation of gene expression#GO:0010608;biological regulation#GO:0065007;regulation of translation#GO:0006417;translational elongation#GO:0006414;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 CIOIN|Ensembl=ENSCING00000006105.3|UniProtKB=F6YWK0 F6YWK0 LOC100183493 PTHR12281:SF12 RP42 RELATED DEFECTIVE IN CULLIN NEDDYLATION PROTEIN cullin family protein binding#GO:0097602;enzyme binding#GO:0019899;ubiquitin-like protein conjugating enzyme binding#GO:0044390;protein binding#GO:0005515;ubiquitin-like protein binding#GO:0032182;binding#GO:0005488 protein neddylation#GO:0045116;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;transferase complex#GO:1990234 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000012775.2|UniProtKB=F6Y1B6 F6Y1B6 LOC100185362 PTHR12489:SF19 LIPOMA HMGIC FUSION PARTNER-LIKE PROTEIN LHFPL TETRASPAN SUBFAMILY MEMBER 2 PROTEIN cellular anatomical entity#GO:0110165;membrane#GO:0016020 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000018912.1|UniProtKB=H2XXC3 H2XXC3 PTHR11040:SF140 ZINC/IRON TRANSPORTER ZRT (ZRT), IRT- (IRT-) LIKE PROTEIN TRANSPORTER inorganic molecular entity transmembrane transporter activity#GO:0015318;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;inorganic cation transmembrane transporter activity#GO:0022890;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075 localization#GO:0051179;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;monoatomic cation transport#GO:0006812;transition metal ion transport#GO:0000041;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;monoatomic ion transport#GO:0006811;monoatomic cation transmembrane transport#GO:0098655 cellular anatomical entity#GO:0110165;membrane#GO:0016020 secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000004875.3|UniProtKB=F6SPI7 F6SPI7 PTHR45752:SF76 LEUCINE-RICH REPEAT-CONTAINING FLYERS-CUP, ISOFORM F scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000012512.2|UniProtKB=F7BE54 F7BE54 PTHR31497:SF0 AUTOCRINE PROLIFERATION REPRESSOR PROTEIN A AUTOCRINE PROLIFERATION REPRESSOR PROTEIN A CIOIN|Ensembl=ENSCING00000008097.3|UniProtKB=F6YNH3 F6YNH3 PTHR21625:SF1 NYD-SP28 PROTEIN DYNEIN REGULATORY COMPLEX PROTEIN 1 regulation of microtubule-based process#GO:0032886;cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cell projection organization#GO:0030030;microtubule cytoskeleton organization#GO:0000226;cilium or flagellum-dependent cell motility#GO:0001539;protein-containing complex assembly#GO:0065003;cell motility#GO:0048870;cellular component organization#GO:0016043;axoneme assembly#GO:0035082;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031;regulation of biological process#GO:0050789;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cilium-dependent cell motility#GO:0060285;microtubule-based process#GO:0007017;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;regulation of cellular process#GO:0050794;microtubule bundle formation#GO:0001578;axonemal dynein complex assembly#GO:0070286;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;plasma membrane bounded cell projection assembly#GO:0120031 axoneme#GO:0005930;cytoplasmic region#GO:0099568;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;plasma membrane bounded cell projection cytoplasm#GO:0032838;membrane-bounded organelle#GO:0043227;ciliary plasm#GO:0097014;cytoskeleton#GO:0005856;cell projection#GO:0042995;cilium#GO:0005929 CIOIN|Ensembl=ENSCING00000009935.3|UniProtKB=F6VNF4 F6VNF4 PTHR21616:SF3 CENTROSOME SPINDLE POLE ASSOCIATED PROTEIN SUBFAMILY NOT NAMED regulation of biological process#GO:0050789;positive regulation of cell division#GO:0051781;positive regulation of cell cycle process#GO:0090068;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;positive regulation of cell cycle#GO:0045787;regulation of cell division#GO:0051302;positive regulation of biological process#GO:0048518;regulation of cytokinesis#GO:0032465;positive regulation of cellular process#GO:0048522;regulation of cell cycle process#GO:0010564 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;spindle pole#GO:0000922;microtubule organizing center#GO:0005815;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;spindle#GO:0005819;centrosome#GO:0005813;intracellular anatomical structure#GO:0005622 centromere DNA-binding protein#PC00071 CIOIN|Ensembl=ENSCING00000010459.3|UniProtKB=F6VT08 F6VT08 LOC100184477 PTHR11516:SF60 PYRUVATE DEHYDROGENASE E1 COMPONENT, ALPHA SUBUNIT BACTERIAL AND ORGANELLAR PYRUVATE DEHYDROGENASE E1 COMPONENT SUBUNIT ALPHA oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;amide metabolic process#GO:0043603;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;acyl-CoA metabolic process#GO:0006637;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;monocarboxylic acid metabolic process#GO:0032787;purine ribonucleotide metabolic process#GO:0009150;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;carboxylic acid metabolic process#GO:0019752;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 dehydrogenase#PC00092;oxidoreductase#PC00176 TCA cycle#P00051>Pyruvate Dehydrogenase#P01266;Pyruvate metabolism#P02772>Pyruvate Dehydrogenase#P03133 CIOIN|Ensembl=ENSCING00000009273.3|UniProtKB=F6S0L5 F6S0L5 PTHR12195:SF0 CYTOPLASMIC FMR1-INTERACTING PROTEIN-RELATED CYTOPLASMIC FMR1-INTERACTING PROTEIN nucleic acid binding#GO:0003676;RNA binding#GO:0003723;RNA cap binding#GO:0000339;binding#GO:0005488;organic cyclic compound binding#GO:0097159 regulation of protein metabolic process#GO:0051246;regulation of amide metabolic process#GO:0034248;regulation of nitrogen compound metabolic process#GO:0051171;developmental process#GO:0032502;cell morphogenesis#GO:0000902;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;anatomical structure morphogenesis#GO:0009653;regulation of cellular process#GO:0050794;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;post-transcriptional regulation of gene expression#GO:0010608;biological regulation#GO:0065007;regulation of translation#GO:0006417;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 Huntington disease#P00029>p53#P00797 CIOIN|Ensembl=ENSCING00000019945.1|UniProtKB=H2XT15 H2XT15 PTHR23194:SF16 PYGOPUS PROTEIN PYGOPUS Wnt signaling pathway#P00057>Pygo#P01464 CIOIN|Ensembl=ENSCING00000013096.2|UniProtKB=F6SGZ6 F6SGZ6 LOC100178072 PTHR13076:SF9 COILED-COIL AND C2 DOMAIN-CONTAINING PROTEIN 1-LIKE COILED-COIL AND C2 DOMAIN-CONTAINING PROTEIN 1-LIKE CIOIN|Ensembl=ENSCING00000004449.3|UniProtKB=F6XDV6 F6XDV6 LOC100175135 PTHR12887:SF11 NANOS PROTEIN NANOS HOMOLOG 1 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 negative regulation of gene expression#GO:0010629;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;regulation of amide metabolic process#GO:0034248;cellular process involved in reproduction in multicellular organism#GO:0022412;regulation of nitrogen compound metabolic process#GO:0051171;developmental process#GO:0032502;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;regulation of biosynthetic process#GO:0009889;reproductive process#GO:0022414;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;multicellular organismal reproductive process#GO:0048609;germ cell development#GO:0007281;cellular developmental process#GO:0048869;gamete generation#GO:0007276;negative regulation of biosynthetic process#GO:0009890;multicellular organism reproduction#GO:0032504;oogenesis#GO:0048477;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;cellular process#GO:0009987;negative regulation of nitrogen compound metabolic process#GO:0051172;cell development#GO:0048468;developmental process involved in reproduction#GO:0003006;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of translation#GO:0017148;reproduction#GO:0000003;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of macromolecule metabolic process#GO:0010605;sexual reproduction#GO:0019953;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of translation#GO:0006417;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;perinuclear region of cytoplasm#GO:0048471;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000007382.3|UniProtKB=F6ULS9 F6ULS9 PTHR15668:SF4 JM1 PROTEIN COILED-COIL DOMAIN-CONTAINING PROTEIN 22 cullin family protein binding#GO:0097602;protein binding#GO:0005515;binding#GO:0005488 positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of proteolysis#GO:0030162;regulation of protein metabolic process#GO:0051246;regulation of catabolic process#GO:0009894;positive regulation of proteolysis involved in protein catabolic process#GO:1903052;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060;regulation of proteolysis involved in protein catabolic process#GO:1903050;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of proteolysis#GO:0045862;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;positive regulation of protein metabolic process#GO:0051247;positive regulation of metabolic process#GO:0009893;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;positive regulation of catabolic process#GO:0009896;positive regulation of biological process#GO:0048518;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;regulation of metabolic process#GO:0019222 CIOIN|Ensembl=ENSCING00000022895.1|UniProtKB=H2XQH1 H2XQH1 PTHR10725:SF78 THAP DOMAIN-CONTAINING PROTEIN 9 DNA TRANSPOSASE THAP9 CIOIN|Ensembl=ENSCING00000014620.2|UniProtKB=F6SB61 F6SB61 PTHR11929:SF145 ALPHA- 1,3 -FUCOSYLTRANSFERASE ALPHA-(1,3)-FUCOSYLTRANSFERASE FUT-1 transferase activity#GO:0016740;fucosyltransferase activity#GO:0008417;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 glycosylation#GO:0070085;metabolic process#GO:0008152 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000009443.3|UniProtKB=F7BHB8 F7BHB8 PTHR22883:SF301 ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN PALMITOYLTRANSFERASE ZDHHC12 palmitoyltransferase activity#GO:0016409;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular localization#GO:0051641;macromolecule localization#GO:0033036;macromolecule modification#GO:0043412;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;biosynthetic process#GO:0009058;establishment of protein localization#GO:0045184;establishment of protein localization to membrane#GO:0090150;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;protein palmitoylation#GO:0018345;protein metabolic process#GO:0019538;protein lipidation#GO:0006497;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;localization within membrane#GO:0051668;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein localization to membrane#GO:0072657;organonitrogen compound biosynthetic process#GO:1901566;protein targeting#GO:0006605;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;protein acylation#GO:0043543;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;lipoprotein biosynthetic process#GO:0042158;protein localization#GO:0008104;primary metabolic process#GO:0044238;localization#GO:0051179;protein targeting to membrane#GO:0006612;cellular macromolecule localization#GO:0070727;lipoprotein metabolic process#GO:0042157 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000000882.3|UniProtKB=F6WZH0 F6WZH0 PTHR46698:SF6 CROSSVEINLESS 2 KIELIN_CHORDIN-LIKE PROTEIN regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;positive regulation of cellular process#GO:0048522;regulation of BMP signaling pathway#GO:0030510;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;positive regulation of cell communication#GO:0010647;regulation of cellular response to growth factor stimulus#GO:0090287;biological regulation#GO:0065007;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518 cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 CIOIN|Ensembl=ENSCING00000001307.2|UniProtKB=F6WW36 F6WW36 LOC100184861 PTHR42760:SF83 SHORT-CHAIN DEHYDROGENASES/REDUCTASES FAMILY MEMBER (3R)-3-HYDROXYACYL-COA DEHYDROGENASE oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 organic acid biosynthetic process#GO:0016053;lipid metabolic process#GO:0006629;oxoacid metabolic process#GO:0043436;monocarboxylic acid biosynthetic process#GO:0072330;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;fatty acid metabolic process#GO:0006631;small molecule biosynthetic process#GO:0044283;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;fatty acid biosynthetic process#GO:0006633;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000010608.3|UniProtKB=F6TND9 F6TND9 PTHR24412:SF172 KELCH PROTEIN KELCH-LIKE PROTEIN 10 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000000391.3|UniProtKB=F6SEQ4 F6SEQ4 LOC100181730 PTHR24096:SF149 LONG-CHAIN-FATTY-ACID--COA LIGASE AMP-BINDING DOMAIN-CONTAINING PROTEIN-RELATED ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877 metabolite interconversion enzyme#PC00262;ligase#PC00142 CIOIN|Ensembl=ENSCING00000002621.3|UniProtKB=F7B2R9 F7B2R9 PTHR43311:SF2 GLUTAMATE--TRNA LIGASE GLUTAMATE--TRNA LIGASE, MITOCHONDRIAL-RELATED catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;ligase activity#GO:0016874;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;peptide biosynthetic process#GO:0043043;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 aminoacyl-tRNA synthetase#PC00047;translational protein#PC00263 Heme biosynthesis#P02746>Glutamyl-tRNA-synthetase#P02977 CIOIN|Ensembl=ENSCING00000014899.2|UniProtKB=F6YRC1 F6YRC1 LOC100180815 PTHR12650:SF15 40S RIBOSOMAL PROTEIN S30/UBIQUITIN-LIKE PROTEIN FUBI RIBOSOMAL PROTEIN S30, ISOFORM A cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic small ribosomal subunit#GO:0022627;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;small ribosomal subunit#GO:0015935;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000001017.3|UniProtKB=F6XBM6 F6XBM6 PTHR11972:SF208 NADPH OXIDASE DUAL OXIDASE-LIKE PROTEIN oxidoreductase activity, acting on NAD(P)H#GO:0016651;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 cellular metabolic process#GO:0044237;response to stimulus#GO:0050896;response to stress#GO:0006950;cellular process#GO:0009987;defense response#GO:0006952;metabolic process#GO:0008152 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;plasma membrane protein complex#GO:0098797;oxidoreductase complex#GO:1990204;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 oxidase#PC00175;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000014405.2|UniProtKB=F6YH98 F6YH98 PTHR10378:SF19 LIM DOMAIN-BINDING PROTEIN CHIP, ISOFORM B positive regulation of nitrogen compound metabolic process#GO:0051173;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;positive regulation of RNA biosynthetic process#GO:1902680;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of RNA biosynthetic process#GO:1902679;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of transcription by RNA polymerase II#GO:0000122;positive regulation of biological process#GO:0048518;negative regulation of cellular process#GO:0048523;negative regulation of biosynthetic process#GO:0009890;regulation of DNA-templated transcription#GO:0006355;negative regulation of metabolic process#GO:0009892;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;positive regulation of RNA metabolic process#GO:0051254;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 gene-specific transcriptional regulator#PC00264;transcription cofactor#PC00217 CIOIN|Ensembl=ENSCING00000013216.2|UniProtKB=F6V5K2 F6V5K2 PTHR12626:SF0 PROGRAMMED CELL DEATH 4 PROGRAMMED CELL DEATH PROTEIN 4 translation factor#PC00223;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000002188.3|UniProtKB=F6S578 F6S578 LOC100186487 PTHR10721:SF1 MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM44 MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM44 protein binding#GO:0005515;protein-folding chaperone binding#GO:0051087;binding#GO:0005488 cellular localization#GO:0051641;transmembrane transport#GO:0055085;macromolecule localization#GO:0033036;transport#GO:0006810;protein transmembrane transport#GO:0071806;protein targeting#GO:0006605;nitrogen compound transport#GO:0071705;establishment of protein localization to organelle#GO:0072594;protein localization to mitochondrion#GO:0070585;cellular process#GO:0009987;protein transmembrane import into intracellular organelle#GO:0044743;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;mitochondrial transport#GO:0006839;organic substance transport#GO:0071702;protein import into mitochondrial matrix#GO:0030150;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein targeting to mitochondrion#GO:0006626;establishment of protein localization to mitochondrion#GO:0072655;protein transport#GO:0015031;protein localization to organelle#GO:0033365;mitochondrial transmembrane transport#GO:1990542 envelope#GO:0031975;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;organelle membrane#GO:0031090;organelle inner membrane#GO:0019866;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227 transporter#PC00227 CIOIN|Ensembl=ENSCING00000014661.2|UniProtKB=F7BHW5 F7BHW5 PTHR12716:SF8 TRANSCRIPTION INITIATION FACTOR IIE, BETA SUBUNIT TRANSCRIPTION INITIATION FACTOR IIE SUBUNIT BETA basal RNA polymerase II transcription machinery binding#GO:0001099;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;basal transcription machinery binding#GO:0001098;transcription factor binding#GO:0008134;binding#GO:0005488 cellular aromatic compound metabolic process#GO:0006725;DNA-templated transcription#GO:0006351;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;RNA biosynthetic process#GO:0032774;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;transcription initiation at RNA polymerase II promoter#GO:0006367;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nucleobase-containing compound biosynthetic process#GO:0034654;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;DNA-templated transcription initiation#GO:0006352;aromatic compound biosynthetic process#GO:0019438;transcription by RNA polymerase II#GO:0006366;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;DNA-directed RNA polymerase complex#GO:0000428;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695;RNA polymerase II, holoenzyme#GO:0016591;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;transcription regulator complex#GO:0005667;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 RNA metabolism protein#PC00031;general transcription factor#PC00259 General transcription regulation#P00023>TFIIE#P00666;Transcription regulation by bZIP transcription factor#P00055>TFIIEbeta#P01386;Transcription regulation by bZIP transcription factor#P00055>TFIIE#P01395;General transcription regulation#P00023>TFIIEbeta#P00659 CIOIN|Ensembl=ENSCING00000002969.3|UniProtKB=F6R3E1 F6R3E1 LOC100177479 PTHR11937:SF573 ACTIN ACTIN-LIKE intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 actin and actin related protein#PC00039;cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 Alzheimer disease-presenilin pathway#P00004>actin#P00114;Nicotinic acetylcholine receptor signaling pathway#P00044>Actin#P01090;Huntington disease#P00029>Actin#P00807;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>F-actin#P00858;Cadherin signaling pathway#P00012>F-actin#P00470;Cytoskeletal regulation by Rho GTPase#P00016>Actin#P00512 CIOIN|Ensembl=ENSCING00000000645.3|UniProtKB=F6RKK1 F6RKK1 PTHR24115:SF578 KINESIN-RELATED KINESIN-LIKE PROTEIN KIFC1 pyrophosphatase activity#GO:0016462;cytoskeletal protein binding#GO:0008092;microtubule motor activity#GO:0003777;tubulin binding#GO:0015631;ATP-dependent activity#GO:0140657;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;cytoskeletal motor activity#GO:0003774;microtubule binding#GO:0008017;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;ribonucleoside triphosphate phosphatase activity#GO:0017111;ATP hydrolysis activity#GO:0016887 microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;microtubule associated complex#GO:0005875;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 CIOIN|Ensembl=ENSCING00000023365.1|UniProtKB=H2Y3T6 H2Y3T6 PTHR24070:SF17 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY RAS-LIKE PROTEIN 2 GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;ion binding#GO:0043167;anion binding#GO:0043168 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 small GTPase#PC00208;G-protein#PC00020 TGF-beta signaling pathway#P00052>Ras-GDP#P01291;FGF signaling pathway#P00021>Ras#P00633;TGF-beta signaling pathway#P00052>Ras-GTP#P01280;PDGF signaling pathway#P00047>Ras#P01154;EGF receptor signaling pathway#P00018>Ras#P00552;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Ras#P00869;Ras Pathway#P04393>Ras#P04547;PI3 kinase pathway#P00048>Ras#P01182;p53 pathway feedback loops 2#P04398>Ras#P04651;Integrin signalling pathway#P00034>Ras#P00916 CIOIN|Ensembl=ENSCING00000001758.3|UniProtKB=F7A4D7 F7A4D7 PTHR48017:SF48 OS05G0424000 PROTEIN-RELATED MAHOGANY CIOIN|Ensembl=ENSCING00000003020.3|UniProtKB=F6PPP8 F6PPP8 PTHR11254:SF440 HECT DOMAIN UBIQUITIN-PROTEIN LIGASE E3 UBIQUITIN-PROTEIN LIGASE NEDD-4 ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E3#P01490 CIOIN|Ensembl=ENSCING00000005317.3|UniProtKB=F7BPR4 F7BPR4 PTHR31075:SF4 CENTROSOMAL PROTEIN OF 85 KDA CENTROSOMAL PROTEIN OF 85 KDA intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;centrosome#GO:0005813 CIOIN|Ensembl=ENSCING00000008091.3|UniProtKB=F6Z672 F6Z672 PTHR12131:SF1 ATP-DEPENDENT RNA AND DNA HELICASE ATP-DEPENDENT RNA HELICASE SUPV3L1, MITOCHONDRIAL-RELATED DNA metabolism protein#PC00009 CIOIN|Ensembl=ENSCING00000009385.3|UniProtKB=F6WBE9 F6WBE9 PTHR11130:SF0 GLUTATHIONE SYNTHETASE GLUTATHIONE SYNTHETASE ligase activity#GO:0016874;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;amide binding#GO:0033218;peptide binding#GO:0042277;ion binding#GO:0043167;anion binding#GO:0043168 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 ligase#PC00142;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000007209.3|UniProtKB=F6Y7E9 F6Y7E9 LOC101242128 PTHR11524:SF16 60S RIBOSOMAL PROTEIN L7 LARGE RIBOSOMAL SUBUNIT PROTEIN UL30 structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;structural molecule activity#GO:0005198;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;RNA processing#GO:0006396;gene expression#GO:0010467;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;ribosomal large subunit biogenesis#GO:0042273;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;maturation of LSU-rRNA#GO:0000470;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic large ribosomal subunit#GO:0022625;large ribosomal subunit#GO:0015934;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 CIOIN|Ensembl=ENSCING00000022350.1|UniProtKB=H2XRB0 H2XRB0 PTHR19444:SF13 UNC-93 RELATED PROTEIN UNC-93 HOMOLOG A membrane-bound signaling molecule#PC00152 CIOIN|Ensembl=ENSCING00000024128.1|UniProtKB=H2Y1K5 H2Y1K5 PTHR15407:SF28 FUKUTIN-RELATED RIBITOL-5-PHOSPHATE TRANSFERASE FKTN glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein glycosylation#GO:0006486;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;glycosylation#GO:0070085;glycoprotein metabolic process#GO:0009100;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 CIOIN|Ensembl=ENSCING00000014387.2|UniProtKB=A0A1W3JGQ0 A0A1W3JGQ0 LOC100186067 PTHR21236:SF2 GOLGI MEMBRANE PROTEIN YIP1 PROTEIN YIPF endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;vesicle fusion#GO:0006906;cellular localization#GO:0051641;Golgi organization#GO:0007030;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;transport#GO:0006810;endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;membrane fusion#GO:0061025;establishment of localization#GO:0051234;organelle organization#GO:0006996;establishment of localization in cell#GO:0051649;vesicle organization#GO:0016050;intracellular transport#GO:0046907;organelle fusion#GO:0048284 cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;Golgi apparatus subcompartment#GO:0098791;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 structural protein#PC00211 CIOIN|Ensembl=ENSCING00000013639.2|UniProtKB=F6Z7K7 F6Z7K7 LOC100179408 PTHR10845:SF259 REGULATOR OF G PROTEIN SIGNALING RGS DOMAIN-CONTAINING PROTEIN-RELATED G-protein modulator#PC00022;protein-binding activity modulator#PC00095;GTPase-activating protein#PC00257 CIOIN|Ensembl=ENSCING00000024446.1|UniProtKB=H2Y2K4 H2Y2K4 PTHR10572:SF24 3-HYDROXY-3-METHYLGLUTARYL-COENZYME A REDUCTASE 3-HYDROXY-3-METHYLGLUTARYL-COENZYME A REDUCTASE reductase#PC00198;oxidoreductase#PC00176 Cholesterol biosynthesis#P00014>Hydroxymethyl glutaryl CoA reductase#P00491 CIOIN|Ensembl=ENSCING00000020252.1|UniProtKB=H2XM25 H2XM25 PTHR24412:SF500 KELCH PROTEIN CHROMOSOME UNDETERMINED SCAFFOLD_42, WHOLE GENOME SHOTGUN SEQUENCE scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000011938.2|UniProtKB=F6PXZ5 F6PXZ5 LOC100184422 PTHR16230:SF3 CAPPUCCINO BIOGENESIS OF LYSOSOMAL ORGANELLES COMPLEX-1, SUBUNIT 4, CAPPUCCINO intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991 CIOIN|Ensembl=ENSCING00000004495.3|UniProtKB=A0A1W5BGR0 A0A1W5BGR0 LOC100175973 PTHR23320:SF173 MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MS4A -RELATED MARVEL DOMAIN-CONTAINING PROTEIN-RELATED transporter#PC00227 CIOIN|Ensembl=ENSCING00000006397.3|UniProtKB=F7AX01 F7AX01 PTHR42985:SF45 SODIUM-COUPLED MONOCARBOXYLATE TRANSPORTER SODIUM_IODIDE COTRANSPORTER-LIKE symporter activity#GO:0015293;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 localization#GO:0051179;monoatomic cation transport#GO:0006812;sodium ion transport#GO:0006814;metal ion transport#GO:0030001;establishment of localization#GO:0051234;monoatomic ion transport#GO:0006811;transport#GO:0006810 secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000006821.3|UniProtKB=F6TZG1 F6TZG1 PTHR10342:SF274 ARYLSULFATASE ARYLSULFATASE B CIOIN|Ensembl=ENSCING00000004211.3|UniProtKB=F6YGR5 F6YGR5 PTHR45850:SF1 SORTING NEXIN FAMILY MEMBER SORTING NEXIN 6, ISOFORM B scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000023042.1|UniProtKB=Q4H3M8 Q4H3M8 Ci-Emx PTHR24339:SF28 HOMEOBOX PROTEIN EMX-RELATED E5-RELATED sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 CIOIN|Ensembl=ENSCING00000009065.3|UniProtKB=F6R213 F6R213 PTHR32086:SF0 FANCONI ANEMIA GROUP D2 PROTEIN FANCONI ANEMIA GROUP D2 PROTEIN enzyme binding#GO:0019899;protein binding#GO:0005515;binding#GO:0005488 DNA repair#GO:0006281;DNA damage checkpoint signaling#GO:0000077;homologous chromosome segregation#GO:0045143;mitotic cell cycle checkpoint signaling#GO:0007093;nuclear division#GO:0000280;nucleobase-containing compound metabolic process#GO:0006139;chromosome segregation#GO:0007059;regulation of biological process#GO:0050789;cell cycle checkpoint signaling#GO:0000075;DNA damage response#GO:0006974;mitotic cell cycle#GO:0000278;interstrand cross-link repair#GO:0036297;nitrogen compound metabolic process#GO:0006807;meiosis I cell cycle process#GO:0061982;reproductive process#GO:0022414;intracellular signal transduction#GO:0035556;meiosis I#GO:0007127;organic substance metabolic process#GO:0071704;nuclear chromosome segregation#GO:0098813;negative regulation of cell cycle#GO:0045786;macromolecule metabolic process#GO:0043170;meiotic cell cycle#GO:0051321;homologous chromosome pairing at meiosis#GO:0007129;regulation of cell cycle phase transition#GO:1901987;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;regulation of cell cycle process#GO:0010564;cellular component organization or biogenesis#GO:0071840;response to stress#GO:0006950;reproduction#GO:0000003;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;sexual reproduction#GO:0019953;cellular response to stress#GO:0033554;cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;double-strand break repair#GO:0006302;mitotic intra-S DNA damage checkpoint signaling#GO:0031573;cell cycle process#GO:0022402;negative regulation of cell cycle process#GO:0010948;mitotic cell cycle process#GO:1903047;reciprocal homologous recombination#GO:0140527;chromosome organization involved in meiotic cell cycle#GO:0070192;organic cyclic compound metabolic process#GO:1901360;meiotic cell cycle process#GO:1903046;signal transduction in response to DNA damage#GO:0042770;reciprocal meiotic recombination#GO:0007131;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of mitotic cell cycle#GO:0045930;cellular process#GO:0009987;meiotic chromosome segregation#GO:0045132;DNA integrity checkpoint signaling#GO:0031570;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;organelle organization#GO:0006996;meiotic nuclear division#GO:0140013;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;organelle fission#GO:0048285;mitotic DNA integrity checkpoint signaling#GO:0044774;homologous recombination#GO:0035825;mitotic DNA damage checkpoint signaling#GO:0044773;regulation of mitotic cell cycle#GO:0007346;DNA metabolic process#GO:0006259 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;condensed chromosome#GO:0000793;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000021644.1|UniProtKB=F6RRT5 F6RRT5 PTHR22901:SF0 SIALATE O-ACETYLESTERASE SIALATE O-ACETYLESTERASE hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 carbohydrate metabolic process#GO:0005975;organic substance metabolic process#GO:0071704;primary metabolic process#GO:0044238;metabolic process#GO:0008152 esterase#PC00097 CIOIN|Ensembl=ENSCING00000004978.3|UniProtKB=F6X8P5 F6X8P5 PTHR12214:SF0 GC-RICH SEQUENCE DNA-BINDING FACTOR LD29489P membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 CIOIN|Ensembl=ENSCING00000023328.1|UniProtKB=H2Y3F1 H2Y3F1 LOC100181036 PTHR12128:SF66 DIHYDRODIPICOLINATE SYNTHASE 4-HYDROXY-2-OXOGLUTARATE ALDOLASE, MITOCHONDRIAL carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829;catalytic activity#GO:0003824;hydro-lyase activity#GO:0016836 lyase#PC00144 Lysine biosynthesis#P02751>Dihydrodipicolinate synthase#P03008 CIOIN|Ensembl=ENSCING00000005492.3|UniProtKB=F7BE41 F7BE41 PTHR12092:SF16 PLECKSTRIN PH DOMAIN-CONTAINING PROTEIN cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actin filament-based process#GO:0030029;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987;organelle organization#GO:0006996 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cytoskeletal protein#PC00085 CIOIN|Ensembl=ENSCING00000005587.3|UniProtKB=F6U3S7 F6U3S7 PTHR18934:SF85 ATP-DEPENDENT RNA HELICASE ATP-DEPENDENT RNA HELICASE DHX8 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;helicase activity#GO:0004386;ATP-dependent activity#GO:0140657;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;catalytic activity, acting on a nucleic acid#GO:0140640 cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;RNA processing#GO:0006396;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;mRNA metabolic process#GO:0016071;cellular component disassembly#GO:0022411;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;mRNA splicing, via spliceosome#GO:0000398;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;protein-containing complex disassembly#GO:0032984;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;protein-containing complex organization#GO:0043933;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;protein-RNA complex organization#GO:0071826;RNA splicing, via transesterification reactions#GO:0000375 ribonucleoprotein complex#GO:1990904;catalytic step 2 spliceosome#GO:0071013;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 RNA helicase#PC00032 CIOIN|Ensembl=ENSCING00000017574.2|UniProtKB=F6SPW4 F6SPW4 LOC100179046 PTHR24543:SF317 MULTICOPPER OXIDASE-RELATED LACTADHERIN oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000004989.1|UniProtKB=F6WMA6 F6WMA6 LOC100182722 PTHR24155:SF10 OSTEOCLAST-STIMULATING FACTOR 1 OSTEOCLAST-STIMULATING FACTOR 1 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 CIOIN|Ensembl=ENSCING00000002477.3|UniProtKB=F7B496 F7B496 PTHR45809:SF3 VIRAL IAP-ASSOCIATED FACTOR HOMOLOG VIRAL IAP-ASSOCIATED FACTOR HOMOLOG macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein folding#GO:0006457;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 viral or transposable element protein#PC00237 CIOIN|Ensembl=ENSCING00000009851.3|UniProtKB=F6XGA8 F6XGA8 LOC100182017 PTHR22752:SF1 G PROTEIN-COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTOR 176 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 G-protein coupled receptor#PC00021 CIOIN|Ensembl=ENSCING00000024550.1|UniProtKB=H2Y0C1 H2Y0C1 PTHR22923:SF62 CEREBELLIN-RELATED CVP18 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000025153.1|UniProtKB=H2XNP3 H2XNP3 PTHR21682:SF2 COILED-COIL DOMAIN-CONTAINING PROTEIN 149 COILED-COIL DOMAIN-CONTAINING PROTEIN 149 CIOIN|Ensembl=ENSCING00000020417.1|UniProtKB=Q1RLD4 Q1RLD4 Ci-ZF(MATRIN)-3 PTHR15491:SF9 FAMILY NOT NAMED CIP1-INTERACTING ZINC FINGER PROTEIN CIOIN|Ensembl=ENSCING00000009484.3|UniProtKB=F6YSL9 F6YSL9 LOC100175863 PTHR24211:SF22 LIM DOMAIN-CONTAINING PROTEIN TESTIN scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000019946.1|UniProtKB=H2XXL7 H2XXL7 LOC100178209 PTHR10894:SF0 NUCLEOLAR PROTEIN 5 NUCLEOLAR PROTEIN NOP5 NOP58 NUCLEOLAR PROTEIN 56 snoRNA binding#GO:0030515;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;sno(s)RNA-containing ribonucleoprotein complex#GO:0005732 RNA metabolism protein#PC00031 CIOIN|Ensembl=ENSCING00000025049.1|UniProtKB=F6W7K5 F6W7K5 PTHR11353:SF24 CHAPERONIN T-COMPLEX PROTEIN 1 SUBUNIT GAMMA protein binding#GO:0005515;unfolded protein binding#GO:0051082;binding#GO:0005488 macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein folding#GO:0006457;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;chaperonin-containing T-complex#GO:0005832;protein folding chaperone complex#GO:0101031;intracellular anatomical structure#GO:0005622 chaperonin#PC00073 CIOIN|Ensembl=ENSCING00000000273.3|UniProtKB=F7A027 F7A027 LOC100185043 PTHR12442:SF26 DYNEIN INTERMEDIATE CHAIN CYTOPLASMIC DYNEIN 2 INTERMEDIATE CHAIN 2 protein binding#GO:0005515;binding#GO:0005488 cilium organization#GO:0044782;cellular localization#GO:0051641;cell projection organization#GO:0030030;transport#GO:0006810;microtubule-based movement#GO:0007018;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;transport along microtubule#GO:0010970;intraciliary transport#GO:0042073;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;microtubule-based transport#GO:0099111;establishment of localization#GO:0051234;microtubule-based process#GO:0007017;organelle organization#GO:0006996;cytoskeleton-dependent intracellular transport#GO:0030705;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;protein-containing complex localization#GO:0031503 catalytic complex#GO:1902494;cytoplasmic region#GO:0099568;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;microtubule associated complex#GO:0005875;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;ciliary plasm#GO:0097014;plasma membrane bounded cell projection cytoplasm#GO:0032838;membrane-bounded organelle#GO:0043227;dynein complex#GO:0030286;cytoskeleton#GO:0005856;cell projection#GO:0042995;cilium#GO:0005929;cytoplasmic dynein complex#GO:0005868 microtubule or microtubule-binding cytoskeletal protein#PC00157 CIOIN|Ensembl=ENSCING00000010048.3|UniProtKB=F6QHE0 F6QHE0 socs7 PTHR10155:SF5 PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT SUPPRESSOR OF CYTOKINE SIGNALING 7 enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207 lipid metabolic process#GO:0006629;phospholipid biosynthetic process#GO:0008654;organophosphate biosynthetic process#GO:0090407;phosphatidylinositol biosynthetic process#GO:0006661;glycerolipid biosynthetic process#GO:0045017;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;phosphatidylinositol metabolic process#GO:0046488;glycerophospholipid metabolic process#GO:0006650;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;phosphatidylinositol phosphate biosynthetic process#GO:0046854;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;glycerophospholipid biosynthetic process#GO:0046474;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;phosphatidylinositol 3-kinase complex#GO:0005942;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;membrane#GO:0016020;transferase complex, transferring phosphorus-containing groups#GO:0061695;extrinsic component of membrane#GO:0019898 kinase modulator#PC00140 Interferon-gamma signaling pathway#P00035>SOCS#P00956;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>SOCS#P00879 CIOIN|Ensembl=ENSCING00000001363.3|UniProtKB=O18313 O18313 hox5 PTHR45771:SF6 HOMEOTIC PROTEIN DEFORMED HOMEOTIC PROTEIN SEX COMBS REDUCED sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;pattern specification process#GO:0007389;positive regulation of biological process#GO:0048518;regulation of DNA-templated transcription#GO:0006355;multicellular organism development#GO:0007275;regionalization#GO:0003002;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;anatomical structure development#GO:0048856;biological regulation#GO:0065007;anterior/posterior pattern specification#GO:0009952;multicellular organismal process#GO:0032501;positive regulation of RNA metabolic process#GO:0051254;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116 CIOIN|Ensembl=ENSCING00000021381.1|UniProtKB=H2XVS5 H2XVS5 PTHR45617:SF165 LEUCINE RICH REPEAT FAMILY PROTEIN COMMON DPR-INTERACTING PROTEIN-RELATED scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000003076.3|UniProtKB=F6PL57 F6PL57 PTHR45797:SF3 RAD54-LIKE TRANSCRIPTIONAL REGULATOR ATRX HOMOLOG membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000024860.1|UniProtKB=H2Y0N3 H2Y0N3 PTHR11771:SF153 LIPOXYGENASE LIPOXYGENASE DOMAIN-CONTAINING PROTEIN oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;dioxygenase activity#GO:0051213 lipid metabolic process#GO:0006629;lipid oxidation#GO:0034440;cellular metabolic process#GO:0044237;lipid modification#GO:0030258;cellular lipid metabolic process#GO:0044255;cellular process#GO:0009987;metabolic process#GO:0008152;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704 oxygenase#PC00177;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000000531.3|UniProtKB=Q86NA9 Q86NA9 ona2 PTHR11929:SF145 ALPHA- 1,3 -FUCOSYLTRANSFERASE ALPHA-(1,3)-FUCOSYLTRANSFERASE FUT-1 transferase activity#GO:0016740;fucosyltransferase activity#GO:0008417;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 glycosylation#GO:0070085;metabolic process#GO:0008152 glycosyltransferase#PC00111;transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000001553.3|UniProtKB=F6XZ43 F6XZ43 LOC100184673 PTHR19248:SF16 ATP-BINDING TRANSPORT PROTEIN-RELATED ATP-BINDING CASSETTE SUB-FAMILY E MEMBER 1 carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;transition metal ion binding#GO:0046914;metal ion binding#GO:0046872;cation binding#GO:0043169;organic cyclic compound binding#GO:0097159;iron ion binding#GO:0005506;nucleoside phosphate binding#GO:1901265;ribosome binding#GO:0043022;ribonucleoprotein complex binding#GO:0043021;heterocyclic compound binding#GO:1901363;protein-containing complex binding#GO:0044877;anion binding#GO:0043168;ion binding#GO:0043167;ATP binding#GO:0005524 protein-containing complex disassembly#GO:0032984;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular component organization#GO:0016043;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;cellular component organization or biogenesis#GO:0071840;translational termination#GO:0006415;peptide biosynthetic process#GO:0043043;cellular component disassembly#GO:0022411;protein-containing complex organization#GO:0043933;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;translational initiation#GO:0006413;protein metabolic process#GO:0019538;amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 CIOIN|Ensembl=ENSCING00000004404.3|UniProtKB=F6YPB3 F6YPB3 LOC100186853 PTHR13134:SF3 TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 13 TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 13 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;vesicle tethering complex#GO:0099023;TRAPP complex#GO:0030008;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000024157.1|UniProtKB=Q1RL63 Q1RL63 Ci-ZF(C2H2)-144 PTHR21213:SF0 GEO09665P1-RELATED ZINC FINGER PROTEIN 706 CIOIN|Ensembl=ENSCING00000004841.3|UniProtKB=F6TZ29 F6TZ29 PTHR10953:SF3 UBIQUITIN-ACTIVATING ENZYME E1 UBIQUITIN-LIKE MODIFIER-ACTIVATING ENZYME ATG7 ligase activity#GO:0016874;transferase activity#GO:0016740;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877;nucleotidyltransferase activity#GO:0016779;thiosulfate sulfurtransferase activity#GO:0004792;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity, acting on a protein#GO:0140096;sulfurtransferase activity#GO:0016783 microautophagy#GO:0016237;cellular component biogenesis#GO:0044085;macroautophagy#GO:0016236;macromolecule modification#GO:0043412;protein modification process#GO:0036211;autophagy of mitochondrion#GO:0000422;response to extracellular stimulus#GO:0009991;biosynthetic process#GO:0009058;post-translational protein modification#GO:0043687;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;cellular component disassembly#GO:0022411;cellular response to starvation#GO:0009267;nitrogen compound metabolic process#GO:0006807;catabolic process#GO:0009056;mitochondrion organization#GO:0007005;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;protein lipidation#GO:0006497;cellular response to extracellular stimulus#GO:0031668;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular component assembly#GO:0022607;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cell communication#GO:0007154;cellular component organization#GO:0016043;response to nutrient levels#GO:0031667;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organelle disassembly#GO:1903008;lipoprotein biosynthetic process#GO:0042158;primary metabolic process#GO:0044238;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;response to stress#GO:0006950;organelle organization#GO:0006996;cellular response to nutrient levels#GO:0031669;response to starvation#GO:0042594;cellular response to external stimulus#GO:0071496;autophagosome assembly#GO:0000045;lipoprotein metabolic process#GO:0042157;cellular response to stress#GO:0033554;piecemeal microautophagy of the nucleus#GO:0034727;autophagy#GO:0006914 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;phagophore assembly site#GO:0000407;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 Ubiquitin proteasome pathway#P00060>E1#P01492 CIOIN|Ensembl=ENSCING00000007154.3|UniProtKB=F7BGH4 F7BGH4 LOC100182258 PTHR24320:SF226 RETINOL DEHYDROGENASE RETINOL DEHYDROGENASE 11 dehydrogenase#PC00092;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000000317.3|UniProtKB=F6ZFV5 F6ZFV5 LOC100180785 PTHR13605:SF4 ER MEMBRANE PROTEIN COMPLEX SUBUNIT 7 ER MEMBRANE PROTEIN COMPLEX SUBUNIT 7 membrane protein complex#GO:0098796;endoplasmic reticulum protein-containing complex#GO:0140534;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;EMC complex#GO:0072546;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 CIOIN|Ensembl=ENSCING00000003040.3|UniProtKB=F6Q6W6 F6Q6W6 PTHR15362:SF7 PHOSPHATIDYLINOSITOL SYNTHASE PHOSPHATIDYLSERINE SYNTHASE 2 transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000022300.1|UniProtKB=H2XS32 H2XS32 PTHR24092:SF190 PROBABLE PHOSPHOLIPID-TRANSPORTING ATPASE PHOSPHOLIPID-TRANSPORTING ATPASE ATPase-coupled intramembrane lipid transporter activity#GO:0140326;ATP-dependent activity#GO:0140657;transporter activity#GO:0005215;lipid transporter activity#GO:0005319 organophosphate ester transport#GO:0015748;Golgi organization#GO:0007030;macromolecule localization#GO:0033036;membrane organization#GO:0061024;transport#GO:0006810;endomembrane system organization#GO:0010256;cellular component organization#GO:0016043;regulation of membrane lipid distribution#GO:0097035;phospholipid transport#GO:0015914;cellular process#GO:0009987;lipid transport#GO:0006869;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;organelle organization#GO:0006996;biological regulation#GO:0065007;lipid translocation#GO:0034204;lipid localization#GO:0010876;phospholipid translocation#GO:0045332 cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;Golgi apparatus subcompartment#GO:0098791;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 primary active transporter#PC00068;transporter#PC00227 CIOIN|Ensembl=ENSCING00000018559.1|UniProtKB=H2XMB4 H2XMB4 LOC100186918 PTHR46252:SF3 BRORIN FAMILY MEMBER KIELIN_CHORDIN-LIKE PROTEIN regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;negative regulation of response to stimulus#GO:0048585;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;regulation of BMP signaling pathway#GO:0030510;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;negative regulation of BMP signaling pathway#GO:0030514;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cellular response to growth factor stimulus#GO:0090287;negative regulation of signal transduction#GO:0009968;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648 receptor complex#GO:0043235;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;plasma membrane signaling receptor complex#GO:0098802;monoatomic ion channel complex#GO:0034702;extracellular region#GO:0005576;transporter complex#GO:1990351;plasma membrane protein complex#GO:0098797;transmembrane transporter complex#GO:1902495;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 CIOIN|Ensembl=ENSCING00000005785.3|UniProtKB=F6RNB7 F6RNB7 LOC100179883 PTHR11113:SF14 N-ACETYLGLUCOSAMINE-6-PHOSPHATE DEACETYLASE N-ACETYLGLUCOSAMINE-6-PHOSPHATE DEACETYLASE hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;deacetylase activity#GO:0019213;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824 carbohydrate derivative metabolic process#GO:1901135;carbohydrate derivative catabolic process#GO:1901136;amino sugar catabolic process#GO:0046348;amino sugar metabolic process#GO:0006040;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 deacetylase#PC00087;hydrolase#PC00121 N-acetylglucosamine metabolism#P02756>N-acetylglucosamine-6-phosphate deacetylase#P03036 CIOIN|Ensembl=ENSCING00000018265.1|UniProtKB=H2XXK2 H2XXK2 PTHR46365:SF1 COPPER TRANSPORT PROTEIN ATOX1 COPPER TRANSPORT PROTEIN ATOX1 localization#GO:0051179;monoatomic cation transport#GO:0006812;transition metal ion transport#GO:0000041;metal ion transport#GO:0030001;establishment of localization#GO:0051234;monoatomic ion transport#GO:0006811;transport#GO:0006810 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000024562.1|UniProtKB=A0A1W3JKJ9 A0A1W3JKJ9 LOC100184417 PTHR11223:SF2 EXPORTIN 1/5 EXPORTIN-1 cellular component biogenesis#GO:0044085;ribosomal subunit export from nucleus#GO:0000054;cellular localization#GO:0051641;organelle localization#GO:0051640;transport#GO:0006810;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;nuclear export#GO:0051168;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;ribonucleoprotein complex biogenesis#GO:0022613;establishment of localization in cell#GO:0051649;ribosome biogenesis#GO:0042254;intracellular transport#GO:0046907;establishment of organelle localization#GO:0051656;nuclear transport#GO:0051169;protein-containing complex localization#GO:0031503 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transporter#PC00227 CIOIN|Ensembl=ENSCING00000006673.3|UniProtKB=H2XWC3 H2XWC3 PTHR12546:SF33 FER-1-LIKE SPERM VESICLE FUSION PROTEIN FER-1 endomembrane system organization#GO:0010256;cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;cellular process#GO:0009987;membrane organization#GO:0061024;plasma membrane organization#GO:0007009 membrane trafficking regulatory protein#PC00151 CIOIN|Ensembl=ENSCING00000003371.3|UniProtKB=F7APX0 F7APX0 PTHR19853:SF1 WD REPEAT CONTAINING PROTEIN 3 WDR3 TBC1 DOMAIN FAMILY MEMBER 31 organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cell projection organization#GO:0030030;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;microtubule cytoskeleton#GO:0015630;ciliary basal body#GO:0036064;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cilium#GO:0005929;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000019274.1|UniProtKB=H2XVD5 H2XVD5 zeta PTHR11599:SF44 PROTEASOME SUBUNIT ALPHA/BETA PROTEASOME SUBUNIT BETA-RELATED hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;proteolysis involved in protein catabolic process#GO:0051603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;peptidase complex#GO:1905368;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;proteasome complex#GO:0000502;membrane-bounded organelle#GO:0043227;endopeptidase complex#GO:1905369;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 protease#PC00190;protein modifying enzyme#PC00260 Parkinson disease#P00049>20S proteasome#P01227 CIOIN|Ensembl=ENSCING00000000336.3|UniProtKB=F6WEC1 F6WEC1 LOC100185508 PTHR44267:SF1 WD REPEAT-CONTAINING PROTEIN 43 WD REPEAT-CONTAINING PROTEIN 43 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;maturation of SSU-rRNA#GO:0030490;ribosomal small subunit biogenesis#GO:0042274;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000024896.1|UniProtKB=H2XKP8 H2XKP8 PTHR22906:SF43 PROPERDIN PROPERDIN CIOIN|Ensembl=ENSCING00000009612.1|UniProtKB=F7AD14 F7AD14 PTHR12258:SF5 JANUS-A/JANUS-B BCDNA.GH02250-RELATED hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;dephosphorylation#GO:0016311;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein dephosphorylation#GO:0006470;cellular metabolic process#GO:0044237;cellular process#GO:0009987;protein metabolic process#GO:0019538;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000005421.3|UniProtKB=F6YQS6 F6YQS6 PTHR11359:SF0 AMP DEAMINASE AMP DEAMINASE hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;deaminase activity#GO:0019239;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;purine ribonucleoside monophosphate metabolic process#GO:0009167;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;nucleotide biosynthetic process#GO:0009165;nucleoside monophosphate metabolic process#GO:0009123;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;IMP metabolic process#GO:0046040;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;purine nucleoside monophosphate metabolic process#GO:0009126;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;ribonucleoside monophosphate metabolic process#GO:0009161;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;IMP biosynthetic process#GO:0006188;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 deaminase#PC00088;hydrolase#PC00121 Purine metabolism#P02769>5'-AMP Deaminase#P03117 CIOIN|Ensembl=ENSCING00000001770.3|UniProtKB=F7A3E4 F7A3E4 zf(traf_ring)-5 PTHR19865:SF2 U3 SMALL NUCLEOLAR RNA INTERACTING PROTEIN 2 F-BOX AND WD REPEAT DOMAIN-CONTAINING 11-A snoRNA binding#GO:0030515;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 small-subunit processome#GO:0032040;ribonucleoprotein complex#GO:1990904;preribosome#GO:0030684;protein-containing complex#GO:0032991 Wnt signaling pathway#P00057>betaTrCP#P01454 CIOIN|Ensembl=ENSCING00000023965.1|UniProtKB=H2XQS5 H2XQS5 PTHR43503:SF4 MCG48959-RELATED PEROXIREDOXIN-6 homeostatic process#GO:0042592;cellular homeostasis#GO:0019725 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 peroxidase#PC00180;oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000006806.3|UniProtKB=Q68A32 Q68A32 Ci-Tram1_2 PTHR12371:SF11 TRANSLOCATION ASSOCIATED MEMBRANE PROTEIN TRANSLOCATING CHAIN-ASSOCIATED MEMBRANE PROTEIN protein insertion into ER membrane#GO:0045048;localization within membrane#GO:0051668;cellular localization#GO:0051641;endoplasmic reticulum organization#GO:0007029;macromolecule localization#GO:0033036;membrane organization#GO:0061024;protein localization to membrane#GO:0072657;endomembrane system organization#GO:0010256;cellular component organization#GO:0016043;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of protein localization to membrane#GO:0090150;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;organelle organization#GO:0006996;protein localization to organelle#GO:0033365;protein insertion into membrane#GO:0051205 cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000024911.1|UniProtKB=H2XWL4 H2XWL4 LOC100176877 PTHR20905:SF1 N-ACETYLTRANSFERASE-RELATED AT07410P-RELATED acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;N-acetyltransferase activity#GO:0008080;acyltransferase activity#GO:0016746;acetyltransferase activity#GO:0016407;catalytic activity#GO:0003824;N-acyltransferase activity#GO:0016410 acetyltransferase#PC00038 CIOIN|Ensembl=ENSCING00000007565.3|UniProtKB=Q7YT71 Q7YT71 rhob PTHR24072:SF247 RHO FAMILY GTPASE RAS-LIKE GTP-BINDING PROTEIN RHO1 GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;enzyme binding#GO:0019899;ribonucleoside triphosphate phosphatase activity#GO:0017111;kinase binding#GO:0019900;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;protein kinase binding#GO:0019901;anion binding#GO:0043168;ion binding#GO:0043167 regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;regulation of cellular process#GO:0050794;regulation of organelle organization#GO:0033043;regulation of actin cytoskeleton organization#GO:0032956;biological regulation#GO:0065007;regulation of actin filament-based process#GO:0032970;regulation of cellular component organization#GO:0051128 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 small GTPase#PC00208 CIOIN|Ensembl=ENSCING00000001833.3|UniProtKB=F6VXA3 F6VXA3 PTHR11660:SF57 SOLUTE CARRIER FAMILY 40 MEMBER SOLUTE CARRIER FAMILY 40 MEMBER secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000003902.3|UniProtKB=Q967X2 Q967X2 CK2B PTHR11740:SF0 CASEIN KINASE II SUBUNIT BETA CASEIN KINASE II SUBUNIT BETA protein kinase regulator activity#GO:0019887;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;enzyme regulator activity#GO:0030234 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;transferase complex#GO:1990234;serine/threonine protein kinase complex#GO:1902554;protein kinase complex#GO:1902911;cellular anatomical entity#GO:0110165;intracellular protein-containing complex#GO:0140535;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622 kinase modulator#PC00140 Cadherin signaling pathway#P00012>Casein kinase II#P00462;Wnt signaling pathway#P00057>Casein Kinase 2#P01459;Parkinson disease#P00049>Casein kinase II#P01236 CIOIN|Ensembl=ENSCING00000012433.2|UniProtKB=F6VIB4 F6VIB4 PTHR24179:SF29 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 12 LD46604P phosphatase regulator activity#GO:0019208;enzyme inhibitor activity#GO:0004857;molecular function inhibitor activity#GO:0140678;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 phosphatase modulator#PC00184 CIOIN|Ensembl=ENSCING00000024777.1|UniProtKB=H2XPZ5 H2XPZ5 LOC100185391 PTHR16719:SF0 CYTOCHROME C OXIDASE COPPER CHAPERONE CYTOCHROME C OXIDASE COPPER CHAPERONE chaperone#PC00072 CIOIN|Ensembl=ENSCING00000009414.3|UniProtKB=F6TLX8 F6TLX8 PTHR23077:SF12 AAA-FAMILY ATPASE PEROXISOMAL ATPASE PEX1 pyrophosphatase activity#GO:0016462;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ATP hydrolysis activity#GO:0016887;ribonucleoside triphosphate phosphatase activity#GO:0017111 cellular localization#GO:0051641;intracellular protein transmembrane transport#GO:0065002;transmembrane transport#GO:0055085;macromolecule localization#GO:0033036;protein import into peroxisome matrix#GO:0016558;transport#GO:0006810;protein transmembrane transport#GO:0071806;nitrogen compound transport#GO:0071705;establishment of protein localization to organelle#GO:0072594;cellular component organization#GO:0016043;cellular process#GO:0009987;protein transmembrane import into intracellular organelle#GO:0044743;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;organelle organization#GO:0006996;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;protein localization to organelle#GO:0033365;peroxisome organization#GO:0007031 bounding membrane of organelle#GO:0098588;peroxisomal membrane#GO:0005778;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;peroxisome#GO:0005777;microbody#GO:0042579;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 primary active transporter#PC00068;transporter#PC00227 CIOIN|Ensembl=ENSCING00000012966.2|UniProtKB=F6T5A7 F6T5A7 PTHR24291:SF208 CYTOCHROME P450 FAMILY 4 SUBFAMILY NOT NAMED oxygenase#PC00177;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000003799.3|UniProtKB=F7ACI7 F7ACI7 PTHR24251:SF30 OVOCHYMASE-RELATED MEMBRANE FRIZZLED-RELATED PROTEIN serine protease#PC00203;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000019774.1|UniProtKB=H2XSC7 H2XSC7 PTHR31872:SF7 TRANSMEMBRANE PROTEIN 179 TRANSMEMBRANE PROTEIN 179B-LIKE CIOIN|Ensembl=ENSCING00000014581.2|UniProtKB=F6UB26 F6UB26 PTHR34400:SF4 FAMILY NOT NAMED MEMBRANE PROTEIN CIOIN|Ensembl=ENSCING00000000532.3|UniProtKB=F6V1J1 F6V1J1 PTHR11339:SF410 EXTRACELLULAR MATRIX GLYCOPROTEIN RELATED INTESTINAL MUCIN-LIKE PROTEIN extracellular matrix protein#PC00102 CIOIN|Ensembl=ENSCING00000001082.3|UniProtKB=F7AGK5 F7AGK5 PTHR10250:SF26 MICROSOMAL GLUTATHIONE S-TRANSFERASE GLUTATHIONE S-TRANSFERASE 3, MITOCHONDRIAL glutathione transferase activity#GO:0004364;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;antioxidant activity#GO:0016209;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 envelope#GO:0031975;cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;nuclear envelope#GO:0005635;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000002433.3|UniProtKB=F7AJJ9 F7AJJ9 PTHR19134:SF550 RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE PROTEIN-TYROSINE-PHOSPHATASE hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;protein tyrosine phosphatase activity#GO:0004725;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 protein phosphatase#PC00195;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000021663.1|UniProtKB=H2XWJ8 H2XWJ8 LOC100181042 PTHR20863:SF28 ACYL CARRIER PROTEIN ACYL CARRIER PROTEIN, MITOCHONDRIAL small molecule binding#GO:0036094;binding#GO:0005488 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 transfer/carrier protein#PC00219 CIOIN|Ensembl=ENSCING00000011544.2|UniProtKB=F6TCI5 F6TCI5 PTHR10579:SF43 CALCIUM-ACTIVATED CHLORIDE CHANNEL REGULATOR ZINC FINGER (C3HC4-TYPE RING FINGER) FAMILY PROTEIN ion channel#PC00133;transporter#PC00227 CIOIN|Ensembl=ENSCING00000000371.3|UniProtKB=F6VRS6 F6VRS6 PTHR13720:SF18 WD-40 REPEAT PROTEIN FI23230P1 cytoskeletal protein#PC00085;microtubule or microtubule-binding cytoskeletal protein#PC00157 CIOIN|Ensembl=ENSCING00000017257.2|UniProtKB=H2XRT7 H2XRT7 PTHR24300:SF397 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 2U1 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;tetrapyrrole binding#GO:0046906;steroid hydroxylase activity#GO:0008395;oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497;heme binding#GO:0020037 response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;response to chemical#GO:0042221;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 oxygenase#PC00177;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000011718.2|UniProtKB=F6W0C3 F6W0C3 PTHR42921:SF1 ACETOACETYL-COA SYNTHETASE ACETOACETYL-COA SYNTHETASE ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877 ligase#PC00142 CIOIN|Ensembl=ENSCING00000018956.1|UniProtKB=Q4H3A8 Q4H3A8 Ci-Irx-A PTHR11211:SF40 IROQUOIS-CLASS HOMEODOMAIN PROTEIN IRX MIRROR, ISOFORM C sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular developmental process#GO:0048869;neurogenesis#GO:0022008;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;multicellular organism development#GO:0007275;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;cell development#GO:0048468;system development#GO:0048731;cell differentiation#GO:0030154;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;anatomical structure development#GO:0048856;biological regulation#GO:0065007;neuron differentiation#GO:0030182;multicellular organismal process#GO:0032501;regulation of macromolecule biosynthetic process#GO:0010556;generation of neurons#GO:0048699;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 CIOIN|Ensembl=ENSCING00000004320.3|UniProtKB=F7BNC1 F7BNC1 PTHR12706:SF30 STRAWBERRY NOTCH-RELATED PROTEIN STRAWBERRY NOTCH-RELATED CIOIN|Ensembl=ENSCING00000003820.3|UniProtKB=F6Y6B3 F6Y6B3 PTHR24393:SF136 ZINC FINGER PROTEIN LD28458P-RELATED DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;double-stranded DNA binding#GO:0003690;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 CIOIN|Ensembl=ENSCING00000023006.1|UniProtKB=H2XMT6 H2XMT6 PTHR18916:SF89 DYNACTIN 1-RELATED MICROTUBULE-BINDING CAP-GLY DOMAIN-CONTAINING PROTEIN cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;microtubule plus-end binding#GO:0051010;binding#GO:0005488 cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;microtubule cytoskeleton organization#GO:0000226;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cellular process#GO:0009987;cytoplasmic microtubule organization#GO:0031122 supramolecular complex#GO:0099080;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;cell cortex#GO:0005938;cell periphery#GO:0071944;supramolecular fiber#GO:0099512;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;microtubule plus-end#GO:0035371;microtubule#GO:0005874 chaperone#PC00072 CIOIN|Ensembl=ENSCING00000023752.1|UniProtKB=H2XJZ5 H2XJZ5 PTHR21648:SF0 FLAGELLAR RADIAL SPOKE PROTEIN 3 RADIAL SPOKE HEAD PROTEIN 3 HOMOLOG membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;cilium#GO:0005929;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025 structural protein#PC00211 CIOIN|Ensembl=ENSCING00000007812.3|UniProtKB=F6WHM9 F6WHM9 PTHR46260:SF3 RING-TYPE DOMAIN-CONTAINING PROTEIN RING-TYPE DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000001998.3|UniProtKB=F6XFJ7 F6XFJ7 PTHR10694:SF129 LYSINE-SPECIFIC DEMETHYLASE LYSINE-SPECIFIC DEMETHYLASE 4B-RELATED histone modifying activity#GO:0140993;demethylase activity#GO:0032451;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;histone demethylase activity#GO:0032452;catalytic activity#GO:0003824;dioxygenase activity#GO:0051213;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491 protein-DNA complex organization#GO:0071824;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biosynthetic process#GO:0009889;protein-containing complex organization#GO:0043933;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;chromatin remodeling#GO:0006338;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077;histone modifying enzyme#PC00261 CIOIN|Ensembl=ENSCING00000020562.1|UniProtKB=H2XMU4 H2XMU4 PTHR11412:SF136 MACROGLOBULIN / COMPLEMENT CD109 ANTIGEN protease inhibitor#PC00191 CIOIN|Ensembl=ENSCING00000022780.1|UniProtKB=H2XY98 H2XY98 PTHR24253:SF162 TRANSMEMBRANE PROTEASE SERINE SERINE PROTEASE 48 serine protease#PC00203;protease#PC00190 CIOIN|Ensembl=ENSCING00000001711.3|UniProtKB=F6TWQ7 F6TWQ7 LOC100182690 PTHR19384:SF84 NITRIC OXIDE SYNTHASE-RELATED METHIONINE SYNTHASE REDUCTASE carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;oxidoreductase activity, acting on metal ions#GO:0016722;nucleoside phosphate binding#GO:1901265;flavin adenine dinucleotide binding#GO:0050660;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;anion binding#GO:0043168;oxidoreductase activity#GO:0016491 organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;proteinogenic amino acid metabolic process#GO:0170039;sulfur compound metabolic process#GO:0006790;proteinogenic amino acid biosynthetic process#GO:0170038;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;aspartate family amino acid biosynthetic process#GO:0009067;alpha-amino acid biosynthetic process#GO:1901607;nitrogen compound metabolic process#GO:0006807;amino acid biosynthetic process#GO:0008652;alpha-amino acid metabolic process#GO:1901605;aspartate family amino acid metabolic process#GO:0009066;small molecule biosynthetic process#GO:0044283;L-amino acid biosynthetic process#GO:0170034;carboxylic acid metabolic process#GO:0019752;L-amino acid metabolic process#GO:0170033;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000021524.1|UniProtKB=H2XZT9 H2XZT9 PTHR13869:SF24 MYELIN P0 RELATED BASEMENT MEMBRANE-SPECIFIC HEPARAN SULFATE PROTEOGLYCAN CORE PROTEIN-LIKE myelin protein#PC00161;structural protein#PC00211 CIOIN|Ensembl=ENSCING00000008144.3|UniProtKB=F6VG31 F6VG31 PTHR23303:SF14 CARBOXYPEPTIDASE REGULATORY REGION-CONTAINING BOS COMPLEX SUBUNIT NOMO1-RELATED cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000004440.3|UniProtKB=F6XF81 F6XF81 LOC100187036 PTHR15835:SF6 NUCLEAR-INTERACTING PARTNER OF ALK ZINC FINGER C3HC-TYPE PROTEIN 1 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000013209.2|UniProtKB=F6VSM2 F6VSM2 LOC100187058 PTHR21237:SF23 GRPE PROTEIN GRPE PROTEIN HOMOLOG, MITOCHONDRIAL nucleotide binding#GO:0000166;unfolded protein binding#GO:0051082;small molecule binding#GO:0036094;molecular function regulator activity#GO:0098772;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;protein binding#GO:0005515 primary active transporter#PC00068;transporter#PC00227 CIOIN|Ensembl=ENSCING00000006276.3|UniProtKB=F6V166 F6V166 PTHR19282:SF551 TETRASPANIN RE08073P-RELATED cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 CIOIN|Ensembl=ENSCING00000002207.3|UniProtKB=F6ZPY0 F6ZPY0 PTHR17271:SF1 PLECKSTRIN HOMOLOGY PH DOMAIN-CONTAINING PROTEIN PROTEIN OUTSPREAD cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 CIOIN|Ensembl=ENSCING00000008588.3|UniProtKB=F6UD40 F6UD40 PTHR10190:SF16 EYES ABSENT DEVELOPMENTAL PROTEIN EYES ABSENT hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;protein tyrosine phosphatase activity#GO:0004725;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of DNA repair#GO:0045739;negative regulation of biological process#GO:0048519;regulation of nitrogen compound metabolic process#GO:0051171;regulation of DNA metabolic process#GO:0051052;positive regulation of cellular metabolic process#GO:0031325;developmental process#GO:0032502;regulation of signaling#GO:0023051;regulation of apoptotic signaling pathway#GO:2001233;regulation of DNA repair#GO:0006282;regulation of biological process#GO:0050789;negative regulation of extrinsic apoptotic signaling pathway#GO:2001237;positive regulation of response to stimulus#GO:0048584;cell differentiation#GO:0030154;regulation of cellular response to stress#GO:0080135;positive regulation of metabolic process#GO:0009893;negative regulation of programmed cell death#GO:0043069;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;regulation of signal transduction#GO:0009966;positive regulation of biological process#GO:0048518;negative regulation of cell communication#GO:0010648;negative regulation of cellular process#GO:0048523;regulation of programmed cell death#GO:0043067;cellular developmental process#GO:0048869;regulation of cell communication#GO:0010646;regulation of apoptotic process#GO:0042981;negative regulation of response to stimulus#GO:0048585;negative regulation of apoptotic signaling pathway#GO:2001234;negative regulation of signaling#GO:0023057;regulation of extrinsic apoptotic signaling pathway#GO:2001236;regulation of response to stress#GO:0080134;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;negative regulation of apoptotic process#GO:0043066;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;regulation of primary metabolic process#GO:0080090;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077;histone modifying enzyme#PC00261 CIOIN|Ensembl=ENSCING00000009352.3|UniProtKB=F6XKZ6 F6XKZ6 PTHR42886:SF29 RE40534P-RELATED PUMMELIG, ISOFORM A CIOIN|Ensembl=ENSCING00000022439.1|UniProtKB=H2Y2N2 H2Y2N2 PTHR12947:SF13 AMSH-LIKE PROTEASE FI19924P1 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;protein K63-linked deubiquitination#GO:0070536;protein modification by small protein removal#GO:0070646;protein deubiquitination#GO:0016579;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;metabolic process#GO:0008152;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 metalloprotease#PC00153;protease#PC00190;protein modifying enzyme#PC00260 CIOIN|Ensembl=ENSCING00000007919.3|UniProtKB=F7AA68 F7AA68 LOC100177416 PTHR15510:SF5 SPERM-ASSOCIATED ANTIGEN 8 SPERM-ASSOCIATED ANTIGEN 8 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of DNA-templated transcription#GO:0006355;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;positive regulation of cellular biosynthetic process#GO:0031328;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of RNA metabolic process#GO:0051254;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 CIOIN|Ensembl=ENSCING00000001487.3|UniProtKB=F6THT6 F6THT6 PTHR23121:SF9 SODIUM-DEPENDENT GLUCOSE TRANSPORTER 1 SODIUM-DEPENDENT GLUCOSE TRANSPORTER 1 transmembrane transporter activity#GO:0022857;sugar transmembrane transporter activity#GO:0051119;transporter activity#GO:0005215;carbohydrate transmembrane transporter activity#GO:0015144 transporter#PC00227 CIOIN|Ensembl=ENSCING00000014567.2|UniProtKB=F6UYZ3 F6UYZ3 PTHR24637:SF420 COLLAGEN NEMATODE CUTICLE COLLAGEN N-TERMINAL DOMAIN-CONTAINING PROTEIN CIOIN|Ensembl=ENSCING00000008900.3|UniProtKB=F6VIT0 F6VIT0 LOC497242 PTHR11814:SF257 SULFATE TRANSPORTER ANION TRANSPORTER SULP-7D inorganic molecular entity transmembrane transporter activity#GO:0015318;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;organic acid transmembrane transporter activity#GO:0005342;chloride transmembrane transporter activity#GO:0015108;monoatomic anion transmembrane transporter activity#GO:0008509;organic anion transmembrane transporter activity#GO:0008514;inorganic anion transmembrane transporter activity#GO:0015103;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 transporter#PC00227 CIOIN|Ensembl=ENSCING00000018716.1|UniProtKB=H2XTW6 H2XTW6 PTHR12128:SF21 DIHYDRODIPICOLINATE SYNTHASE N-ACETYLNEURAMINATE LYASE lyase#PC00144 N-acetylglucosamine metabolism#P02756>N-acetylneuraminate lyase#P03040 CIOIN|Ensembl=ENSCING00000023320.1|UniProtKB=H2XSM1 H2XSM1 PTHR24064:SF577 SOLUTE CARRIER FAMILY 22 MEMBER GH09241P secondary carrier transporter#PC00258;transporter#PC00227 CIOIN|Ensembl=ENSCING00000008243.3|UniProtKB=H2XVW1 H2XVW1 PTHR10625:SF5 HISTONE DEACETYLASE HDAC1-RELATED HISTONE DEACETYLASE histone modifying activity#GO:0140993;histone deacetylase activity#GO:0004407;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;deacetylase activity#GO:0019213;catalytic activity, acting on a protein#GO:0140096 protein-DNA complex organization#GO:0071824;cellular component organization#GO:0016043;cellular process#GO:0009987;epigenetic regulation of gene expression#GO:0040029;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biosynthetic process#GO:0009889;protein-containing complex organization#GO:0043933;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;chromatin remodeling#GO:0006338;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;histone deacetylase complex#GO:0000118;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513 CIOIN|Ensembl=ENSCING00000023160.1|UniProtKB=H2XW88 H2XW88 LOC100180234 PTHR23089:SF33 HISTIDINE TRIAD HIT PROTEIN ADENOSINE 5'-MONOPHOSPHORAMIDASE HINT1 hydrolase activity#GO:0016787;catalytic activity#GO:0003824 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 nucleotide phosphatase#PC00173 CIOIN|Ensembl=ENSCING00000000359.3|UniProtKB=F6WDB5 F6WDB5 LOC100183575 PTHR11256:SF62 BCL-2 RELATED BCL-2 BCL-2 HOMOLOGY REGION 1-3 DOMAIN-CONTAINING PROTEIN protein binding#GO:0005515;binding#GO:0005488 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0043280;intrinsic apoptotic signaling pathway in response to DNA damage#GO:0008630;signal transduction#GO:0007165;positive regulation of cysteine-type endopeptidase activity#GO:2001056;regulation of protein metabolic process#GO:0051246;apoptotic mitochondrial changes#GO:0008637;regulation of cysteine-type endopeptidase activity#GO:2000116;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;positive regulation of proteolysis#GO:0045862;regulation of biological process#GO:0050789;activation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0006919;DNA damage response#GO:0006974;positive regulation of metabolic process#GO:0009893;regulation of molecular function#GO:0065009;apoptotic process#GO:0006915;cell death#GO:0008219;regulation of hydrolase activity#GO:0051336;mitochondrion organization#GO:0007005;intracellular signal transduction#GO:0035556;positive regulation of biological process#GO:0048518;positive regulation of peptidase activity#GO:0010952;signaling#GO:0023052;regulation of proteolysis#GO:0030162;cellular response to stimulus#GO:0051716;positive regulation of catalytic activity#GO:0043085;programmed cell death#GO:0012501;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of hydrolase activity#GO:0051345;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;intrinsic apoptotic signaling pathway#GO:0097193;apoptotic signaling pathway#GO:0097190;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;response to stress#GO:0006950;extrinsic apoptotic signaling pathway#GO:0097191;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of endopeptidase activity#GO:0052548;regulation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0043281;regulation of peptidase activity#GO:0052547;release of cytochrome c from mitochondria#GO:0001836;cellular response to stress#GO:0033554;positive regulation of endopeptidase activity#GO:0010950;regulation of metabolic process#GO:0019222 bounding membrane of organelle#GO:0098588;envelope#GO:0031975;mitochondrial membrane#GO:0031966;mitochondrial outer membrane#GO:0005741;intracellular membrane-bounded organelle#GO:0043231;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867 CIOIN|Ensembl=ENSCING00000000223.3|UniProtKB=F6T3G6 F6T3G6 PTHR13812:SF19 KETIMINE REDUCTASE MU-CRYSTALLIN KETIMINE REDUCTASE MU-CRYSTALLIN reductase#PC00198;oxidoreductase#PC00176 CIOIN|Ensembl=ENSCING00000012545.2|UniProtKB=F7AUB9 F7AUB9 PTHR46120:SF4 BETAINE--HOMOCYSTEINE S-METHYLTRANSFERASE 1 HCY-BINDING DOMAIN-CONTAINING PROTEIN methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824 organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;proteinogenic amino acid metabolic process#GO:0170039;sulfur compound metabolic process#GO:0006790;proteinogenic amino acid biosynthetic process#GO:0170038;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;aspartate family amino acid biosynthetic process#GO:0009067;alpha-amino acid biosynthetic process#GO:1901607;nitrogen compound metabolic process#GO:0006807;amino acid biosynthetic process#GO:0008652;alpha-amino acid metabolic process#GO:1901605;aspartate family amino acid metabolic process#GO:0009066;small molecule biosynthetic process#GO:0044283;L-amino acid biosynthetic process#GO:0170034;carboxylic acid metabolic process#GO:0019752;L-amino acid metabolic process#GO:0170033;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 methyltransferase#PC00155;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000003309.3|UniProtKB=F6W1A6 F6W1A6 LOC104266621 PTHR32419:SF6 GLUTATHIONYL-HYDROQUINONE REDUCTASE GLUTATHIONE S-TRANSFERASE OMEGA-LIKE 1-RELATED glutathione transferase activity#GO:0004364;transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 reductase#PC00198;metabolite interconversion enzyme#PC00262 CIOIN|Ensembl=ENSCING00000023395.1|UniProtKB=H2XW04 H2XW04 PTHR11062:SF381 EXOSTOSIN HEPARAN SULFATE GLYCOSYLTRANSFERASE -RELATED EXOSTOSIN-2 acetylglucosaminyltransferase activity#GO:0008375;glucuronosyltransferase activity#GO:0015020;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194;hexosyltransferase activity#GO:0016758 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111 CIOIN|Ensembl=ENSCING00000017054.2|UniProtKB=F6X2L1 F6X2L1 PTHR11941:SF27 ENOYL-COA HYDRATASE-RELATED ETHYLMALONYL-COA DECARBOXYLASE lipid metabolic process#GO:0006629;oxoacid metabolic process#GO:0043436;cellular metabolic process#GO:0044237;lipid oxidation#GO:0034440;lipid modification#GO:0030258;lipid catabolic process#GO:0016042;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;fatty acid catabolic process#GO:0009062;primary metabolic process#GO:0044238;fatty acid metabolic process#GO:0006631;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;fatty acid beta-oxidation#GO:0006635;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;cellular lipid metabolic process#GO:0044255;carboxylic acid catabolic process#GO:0046395;cellular lipid catabolic process#GO:0044242;carboxylic acid metabolic process#GO:0019752;cellular catabolic process#GO:0044248;monocarboxylic acid catabolic process#GO:0072329;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular anatomical structure#GO:0005622 hydratase#PC00120 Succinate to proprionate conversion#P02777>Methylmalonyl-CoA decarboxylase#P03163